Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | insulin-like growth factor 1 receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.4768 | 0.245 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0158 | 1 | 1 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0072 | 0.373 | 0.0953 |
Schistosoma mansoni | tyrosine kinase | 0.0072 | 0.373 | 0.0953 |
Echinococcus multilocularis | insulin receptor | 0.0158 | 1 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0072 | 0.373 | 0.0953 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0072 | 0.373 | 0.0953 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0072 | 0.373 | 0.0953 |
Schistosoma mansoni | tyrosine kinase | 0.0071 | 0.3637 | 0.0819 |
Brugia malayi | Protein kinase domain containing protein | 0.0087 | 0.486 | 0.2584 |
Schistosoma mansoni | tyrosine kinase | 0.0072 | 0.373 | 0.0953 |
Echinococcus granulosus | insulin receptor | 0.0158 | 1 | 1 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0158 | 1 | 1 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0072 | 0.373 | 0.0953 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0158 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0071 | 0.3637 | 0.0819 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0072 | 0.373 | 0.373 |
Schistosoma mansoni | tyrosine kinase | 0.0071 | 0.3637 | 0.0819 |
Schistosoma mansoni | tyrosine kinase | 0.0158 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0072 | 0.373 | 0.0953 |
Schistosoma mansoni | tyrosine kinase | 0.0158 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.3069 | 0.3069 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0072 | 0.373 | 0.373 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.