Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0078 | 0.1074 | 0.1288 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0078 | 0.1074 | 0.1288 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0078 | 0.1074 | 0.1074 |
Brugia malayi | nuclear receptor NHR-88 | 0.0037 | 0.0394 | 0.0473 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0075 | 0.103 | 0.103 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0107 | 0.1562 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0097 | 0.1384 | 0.8837 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0021 | 0.0025 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0037 | 0.0394 | 0.0473 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0015 | 0.003 | 0.0166 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0078 | 0.1074 | 0.1074 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0017 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0015 | 0.003 | 0.0166 |
Schistosoma mansoni | thyroid hormone receptor | 0.019 | 0.2937 | 0.2937 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0032 | 0.032 | 0.032 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0037 | 0.0394 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Loa Loa (eye worm) | glutathione reductase | 0.0042 | 0.0487 | 0.0582 |
Mycobacterium tuberculosis | Probable reductase | 0.0097 | 0.1384 | 0.8837 |
Plasmodium falciparum | thioredoxin reductase | 0.0042 | 0.0487 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0078 | 0.1074 | 0.1074 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0037 | 0.0394 | 0.0394 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0015 | 0.003 | 0.0166 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0097 | 0.1384 | 0.8837 |
Schistosoma mansoni | jun-related protein | 0.0061 | 0.0797 | 0.0797 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0078 | 0.1074 | 0.1074 |
Echinococcus multilocularis | tumor protein p63 | 0.0302 | 0.4788 | 0.4788 |
Brugia malayi | nuclear receptor RXR | 0.0037 | 0.0394 | 0.0473 |
Echinococcus multilocularis | Ankyrin | 0.0013 | 0.0002 | 0.0002 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0166 | 0.2533 | 0.2533 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0015 | 0.003 | 0.003 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.019 | 0.2937 | 0.2937 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0158 | 0.2397 | 0.2397 |
Brugia malayi | PAS domain containing protein | 0.0054 | 0.0687 | 0.0824 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0078 | 0.1074 | 0.1074 |
Entamoeba histolytica | hypothetical protein | 0.0032 | 0.032 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0078 | 0.1074 | 0.1074 |
Brugia malayi | small heat shock protein | 0.0517 | 0.8335 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0078 | 0.1074 | 0.1286 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0107 | 0.1554 | 0.1863 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.3287 | 0.3942 |
Schistosoma mansoni | nuclear hormone receptor | 0.0037 | 0.0394 | 0.0394 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0015 | 0.003 | 0.0036 |
Echinococcus multilocularis | dna polymerase kappa | 0.0017 | 0.0073 | 0.0073 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0097 | 0.1384 | 0.8837 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0118 | 0.1731 | 0.1731 |
Entamoeba histolytica | hypothetical protein | 0.0032 | 0.032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.1723 | 0.2066 |
Trypanosoma brucei | trypanothione reductase | 0.0042 | 0.0487 | 0.8938 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0046 | 0.0541 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0107 | 0.1562 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0078 | 0.1074 | 0.1074 |
Brugia malayi | nuclear receptor NHR-67 | 0.0037 | 0.0394 | 0.0473 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0042 | 0.0487 | 0.0582 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0078 | 0.1074 | 0.1286 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0017 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0037 | 0.0394 | 0.0471 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0078 | 0.1074 | 0.1286 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0046 | 0.0541 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0041 | 0.0467 | 0.056 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0125 | 0.1853 | 0.1853 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0078 | 0.1074 | 0.1288 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0078 | 0.1074 | 0.1288 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0394 | 0.0473 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0037 | 0.0394 | 0.0394 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0037 | 0.0394 | 0.0471 |
Brugia malayi | hypothetical protein | 0.0212 | 0.3287 | 0.3943 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0017 | 0.0073 | 0.0994 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0212 | 0.3287 | 0.3287 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0078 | 0.1074 | 0.1286 |
Echinococcus multilocularis | dna polymerase eta | 0.0017 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0078 | 0.1074 | 0.1286 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0041 | 0.0467 | 0.0467 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0017 | 0.0073 | 0.1018 |
Schistosoma mansoni | survival motor neuron protein | 0.0043 | 0.0501 | 0.0501 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0015 | 0.0028 | 0.0131 |
Schistosoma mansoni | thyroid hormone receptor | 0.019 | 0.2937 | 0.2937 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1074 | 0.1286 |
Leishmania major | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0994 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1074 | 0.1286 |
Schistosoma mansoni | hypothetical protein | 0.0061 | 0.0797 | 0.0797 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1489 | 0.1785 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0021 | 0.0023 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0015 | 0.0028 | 0.0131 |
Trypanosoma brucei | protein kinase, putative | 0.0046 | 0.0541 | 1 |
Brugia malayi | glutathione reductase | 0.0042 | 0.0487 | 0.0584 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0015 | 0.003 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0107 | 0.1554 | 0.1864 |
Leishmania major | protein kinase, putative | 0.0015 | 0.0028 | 0.0131 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0046 | 0.0541 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0994 |
Leishmania major | trypanothione reductase | 0.0042 | 0.0487 | 0.8956 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0046 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0078 | 0.1074 | 0.1286 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0078 | 0.1074 | 0.1286 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0078 | 0.1074 | 0.1288 |
Brugia malayi | nuclear hormone receptor | 0.0078 | 0.1074 | 0.1288 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0037 | 0.0394 | 0.0473 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0046 | 0.0541 | 1 |
Brugia malayi | bHLH-PAS transcription factor | 0.004 | 0.0453 | 0.0544 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0617 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0467 | 0.0558 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0467 | 0.056 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0015 | 0.0029 | 0.0029 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1074 | 0.1286 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0015 | 0.0029 | 0.0029 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0078 | 0.1074 | 0.417 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0467 | 0.056 |
Schistosoma mansoni | DNA polymerase eta | 0.0017 | 0.0073 | 0.0073 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0097 | 0.1384 | 0.8837 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0078 | 0.1074 | 0.1074 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.2024 | 0.2426 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0042 | 0.0487 | 0.2985 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0017 | 0.0073 | 0.0281 |
Brugia malayi | hypothetical protein | 0.0135 | 0.2024 | 0.2428 |
Trypanosoma brucei | unspecified product | 0.0017 | 0.0073 | 0.0843 |
Echinococcus granulosus | dna polymerase eta | 0.0017 | 0.0073 | 0.0073 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0994 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0078 | 0.1074 | 0.1286 |
Brugia malayi | Thioredoxin reductase | 0.0042 | 0.0487 | 0.0584 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0017 | 0.0073 | 0.0994 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1074 | 0.1286 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1074 | 0.1286 |
Brugia malayi | bZIP transcription factor family protein | 0.0075 | 0.103 | 0.1236 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0015 | 0.003 | 0.0166 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0078 | 0.1074 | 0.1288 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0015 | 0.003 | 0.0166 |
Brugia malayi | nuclear receptor NHR-88 | 0.0078 | 0.1074 | 0.1288 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0015 | 0.003 | 0.5 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0037 | 0.0394 | 0.0394 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0501 | 0.0501 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1497 | 0.1794 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0017 | 0.0073 | 0.0843 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0017 | 0.0073 | 0.0843 |
Echinococcus granulosus | FTZ F1 alpha | 0.0078 | 0.1074 | 0.1074 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0041 | 0.0467 | 0.0467 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0046 | 0.0541 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0212 | 0.3287 | 0.3287 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0032 | 0.032 | 0.032 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0046 | 0.0541 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0046 | 0.0541 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0467 | 0.0558 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0078 | 0.1074 | 0.1074 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0032 | 0.032 | 0.032 |
Brugia malayi | MAP kinase sur-1 | 0.0046 | 0.0541 | 0.0649 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0994 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0078 | 0.1074 | 0.1074 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0037 | 0.0394 | 0.0394 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0078 | 0.1074 | 0.1074 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0041 | 0.0467 | 0.0467 |
Brugia malayi | steroid hormone receptor | 0.0078 | 0.1074 | 0.1288 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0078 | 0.1074 | 0.1074 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0467 | 0.0558 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1074 | 0.1286 |
Onchocerca volvulus | 0.0135 | 0.2024 | 1 | |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0113 | 0.165 | 0.165 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0041 | 0.0467 | 0.056 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0037 | 0.0394 | 0.0473 |
Plasmodium falciparum | glutathione reductase | 0.0042 | 0.0487 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0037 | 0.0394 | 0.0394 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0042 | 0.0487 | 0.8956 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0519 | 0.0621 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1074 | 0.1286 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0046 | 0.0541 | 0.0541 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0078 | 0.1074 | 0.1288 |
Plasmodium vivax | glutathione reductase, putative | 0.0042 | 0.0487 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Schistosoma mansoni | nuclear receptor | 0.0037 | 0.0394 | 0.0394 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0017 | 0.0073 | 0.1018 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0017 | 0.0073 | 0.0281 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0078 | 0.1074 | 0.1288 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0042 | 0.0487 | 0.0487 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0078 | 0.1074 | 0.1288 |
Echinococcus granulosus | dna polymerase kappa | 0.0017 | 0.0073 | 0.0073 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0017 | 0.0073 | 0.0994 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0097 | 0.1384 | 0.8844 |
Schistosoma mansoni | single-minded | 0.0054 | 0.0687 | 0.0687 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0066 | 0.0877 | 0.0877 |
Onchocerca volvulus | 0.0044 | 0.0519 | 0.0768 | |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.032 | 0.032 |
Brugia malayi | nuclear hormone receptor | 0.0037 | 0.0394 | 0.0473 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0107 | 0.1562 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0078 | 0.1074 | 0.1074 |
Onchocerca volvulus | 0.0043 | 0.0501 | 0.0657 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0078 | 0.1074 | 0.1074 |
Echinococcus multilocularis | jun protein | 0.0075 | 0.103 | 0.103 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0046 | 0.0541 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0073 | 0.0085 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0043 | 0.0501 | 0.0601 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0118 | 0.1731 | 0.1731 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Onchocerca volvulus | 0.0059 | 0.0763 | 0.2265 | |
Brugia malayi | hypothetical protein | 0.0059 | 0.0763 | 0.0916 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0843 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0037 | 0.0394 | 0.0394 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0037 | 0.0394 | 0.0394 |
Toxoplasma gondii | thioredoxin reductase | 0.0042 | 0.0487 | 0.8938 |
Brugia malayi | Protein kinase domain containing protein | 0.0013 | 0.0007 | 0.0008 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0013 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Echinococcus multilocularis | transfer RNA-Lys | 0.004 | 0.0453 | 0.0453 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0037 | 0.0394 | 0.0394 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0046 | 0.0541 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0078 | 0.1074 | 0.1288 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0017 | 0.0073 | 0.0073 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0078 | 0.1074 | 0.1074 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0017 | 0.0073 | 0.0073 |
Brugia malayi | conserved hypotetical protein | 0.0037 | 0.0394 | 0.0473 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 0.8335 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0302 | 0.4788 | 0.4788 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0042 | 0.0487 | 0.0487 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0041 | 0.0467 | 0.0558 |
Schistosoma mansoni | nuclear hormone receptor | 0.0078 | 0.1074 | 0.1074 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Leishmania major | DNA polymerase eta, putative | 0.0017 | 0.0073 | 0.0994 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0037 | 0.0394 | 0.0394 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0017 | 0.0073 | 0.0085 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0015 | 0.003 | 0.003 |
Schistosoma mansoni | zinc finger protein | 0.0037 | 0.0394 | 0.0394 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0078 | 0.1074 | 0.1074 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0113 | 0.165 | 0.165 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0037 | 0.0394 | 0.0471 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0078 | 0.1074 | 0.417 |
Schistosoma mansoni | nuclear receptor | 0.0037 | 0.0394 | 0.0394 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0078 | 0.1074 | 0.1074 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0078 | 0.1074 | 0.1074 |
Schistosoma mansoni | coup transcription factor | 0.0078 | 0.1074 | 0.1074 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0046 | 0.0541 | 0.0541 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0066 | 0.0877 | 0.0877 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0078 | 0.1074 | 0.1074 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0046 | 0.0541 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Giardia lamblia | DINP protein human, muc B family | 0.0017 | 0.0073 | 0.0843 |
Entamoeba histolytica | hypothetical protein | 0.0032 | 0.032 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0166 | 0.2533 | 0.2533 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0107 | 0.1562 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0046 | 0.0541 | 1 |
Brugia malayi | tailless protein | 0.0037 | 0.0394 | 0.0473 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0037 | 0.0394 | 0.0394 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0017 | 0.0073 | 0.0087 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0078 | 0.1074 | 0.1288 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0467 | 0.0558 |
Onchocerca volvulus | 0.0117 | 0.1723 | 0.8157 | |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0015 | 0.003 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0046 | 0.0541 | 0.0541 |
Treponema pallidum | NADH oxidase | 0.0015 | 0.003 | 0.5 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0037 | 0.0394 | 0.0394 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0017 | 0.0073 | 0.0843 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0015 | 0.0028 | 0.0131 |
Echinococcus granulosus | Ankyrin | 0.0013 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | putative regulatory protein | 0.004 | 0.0453 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0078 | 0.1074 | 0.1074 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0078 | 0.1074 | 0.1074 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0078 | 0.1074 | 0.417 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0041 | 0.0467 | 0.056 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0394 | 0.0473 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.165 | 0.165 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0015 | 0.0029 | 0.0032 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0046 | 0.0541 | 0.0647 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0017 | 0.0073 | 0.0994 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0017 | 0.0073 | 0.0843 |
Schistosoma mansoni | nuclear hormone receptor | 0.0037 | 0.0394 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1074 | 0.1286 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0097 | 0.1384 | 0.8837 |
Leishmania major | protein kinase, putative | 0.0015 | 0.0028 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0467 | 0.0558 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0078 | 0.1074 | 0.1288 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0078 | 0.1074 | 0.1288 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0103 | 0.1489 | 0.1787 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0044 | 0.0519 | 0.0519 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0046 | 0.0541 | 0.0541 |
Brugia malayi | hypothetical protein | 0.0032 | 0.032 | 0.0384 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0078 | 0.1074 | 0.1288 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0617 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0394 | 0.0471 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0046 | 0.0541 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0078 | 0.1074 | 0.1288 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0078 | 0.1074 | 0.1074 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0037 | 0.0394 | 0.0473 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0046 | 0.0541 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0078 | 0.1074 | 0.1288 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0037 | 0.0394 | 0.0394 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0015 | 0.0028 | 0.0131 |
Echinococcus granulosus | jun protein | 0.0075 | 0.103 | 0.103 |
Entamoeba histolytica | hypothetical protein | 0.0032 | 0.032 | 1 |
Onchocerca volvulus | 0.0041 | 0.0461 | 0.0411 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0041 | 0.0467 | 0.0467 |
Echinococcus granulosus | single minded 2 | 0.004 | 0.0453 | 0.0453 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0037 | 0.0394 | 0.0394 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0037 | 0.0394 | 0.0473 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0017 | 0.0073 | 0.0994 |
Brugia malayi | ecdysone receptor | 0.0037 | 0.0394 | 0.0473 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0996 | 0.1193 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0042 | 0.0487 | 1 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0037 | 0.0394 | 0.0473 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0107 | 0.1554 | 0.1863 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0078 | 0.1074 | 0.1074 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0075 | 0.103 | 0.103 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0078 | 0.1074 | 0.1288 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0015 | 0.003 | 0.003 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0015 | 0.003 | 0.0166 |
Onchocerca volvulus | 0.0078 | 0.1074 | 0.417 | |
Loa Loa (eye worm) | DR-78 | 0.0037 | 0.0394 | 0.0471 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0017 | 0.0073 | 0.0087 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
K app (binding) | = 0.009 uM | Affinity to displace radioligand [3H]-oxotremorine (OXO) at muscarinic acetylcholine receptor from rat cortical homogenate. | ChEMBL. | 2362286 |
K app (binding) | = 0.009 uM | Affinity to displace radioligand [3H]-oxotremorine (OXO) at muscarinic acetylcholine receptor from rat cortical homogenate. | ChEMBL. | 2362286 |
K app (binding) | = 0.082 uM | Ability to displace radioligand [3H]-N-methylscopolamine (NMS) at muscarinic acetylcholine receptor from rat cortical homogenate. | ChEMBL. | 2362286 |
K app (binding) | = 0.082 uM | Ability to displace radioligand [3H]-N-methylscopolamine (NMS) at muscarinic acetylcholine receptor from rat cortical homogenate. | ChEMBL. | 2362286 |
Ratio (binding) | = 9.1 | Ratio of [3H]-N-methylscopolamine (NMS) to [3H]-oxotremorine (OXO) at muscarinic acetylcholine receptor from rat cortical homogenate. | ChEMBL. | 2362286 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.