Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | dihydroorotate dehydrogenase | 0.0328 | 0.1582 | 1 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0328 | 0.1582 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0094 | 0.0342 | 0.0388 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0085 | 0.0292 | 0.1634 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0085 | 0.0292 | 0.1634 |
Brugia malayi | PHD-finger family protein | 0.0033 | 0.0016 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0569 | 0.5816 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.0328 | 0.1582 | 0.1576 |
Brugia malayi | nuclear receptor NHR-67 | 0.0065 | 0.0186 | 0.1142 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0137 | 0.0569 | 0.3574 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0143 | 0.0601 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0569 | 0.5816 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.0328 | 0.1582 | 0.5 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0328 | 0.1582 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0065 | 0.0186 | 0.1859 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0143 | 0.0601 | 0.3775 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0137 | 0.0569 | 0.3574 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0094 | 0.0342 | 0.1959 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0137 | 0.0569 | 0.0563 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0137 | 0.0569 | 0.0586 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0328 | 0.1582 | 1 |
Onchocerca volvulus | 0.0137 | 0.0569 | 0.5008 | |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0065 | 0.0186 | 0.1142 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0137 | 0.0569 | 0.0563 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0033 | 0.0016 | 0.0016 |
Schistosoma mansoni | thyroid hormone receptor | 0.0137 | 0.0569 | 0.0563 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0065 | 0.0186 | 0.0187 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.004 | 0.0356 |
Plasmodium vivax | glutathione reductase, putative | 0.0037 | 0.004 | 0.0219 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0033 | 0.0016 | 0.001 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.0328 | 0.1582 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0137 | 0.0569 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0227 | 0.2283 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0137 | 0.0569 | 0.0563 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0065 | 0.0186 | 0.1142 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0137 | 0.0569 | 0.3574 |
Schistosoma mansoni | nuclear receptor | 0.0065 | 0.0186 | 0.018 |
Loa Loa (eye worm) | DR-78 | 0.0065 | 0.0186 | 0.1859 |
Schistosoma mansoni | zinc finger protein | 0.0065 | 0.0186 | 0.018 |
Plasmodium falciparum | glutathione reductase | 0.0037 | 0.004 | 0.0153 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0137 | 0.0569 | 0.0563 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0033 | 0.0016 | 0.0067 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0137 | 0.0569 | 0.0569 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0137 | 0.0569 | 0.5008 |
Brugia malayi | nuclear hormone receptor | 0.0065 | 0.0186 | 0.1142 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0137 | 0.0569 | 0.3574 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0137 | 0.0569 | 0.5816 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0143 | 0.0601 | 0.0601 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0065 | 0.0186 | 0.1142 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0137 | 0.0569 | 0.0569 |
Onchocerca volvulus | 0.0243 | 0.113 | 1 | |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0137 | 0.0569 | 0.0586 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0107 | 0.0409 | 0.0419 |
Schistosoma mansoni | thyroid hormone receptor | 0.0137 | 0.0569 | 0.0563 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0143 | 0.0601 | 0.0595 |
Plasmodium vivax | hypothetical protein, conserved | 0.0033 | 0.0016 | 0.0067 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0137 | 0.0569 | 0.5816 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0065 | 0.0186 | 0.018 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0065 | 0.0186 | 0.0186 |
Schistosoma mansoni | nuclear hormone receptor | 0.0065 | 0.0186 | 0.018 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0137 | 0.0569 | 0.5816 |
Brugia malayi | nuclear receptor RXR | 0.0065 | 0.0186 | 0.1142 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0137 | 0.0569 | 0.3574 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.0328 | 0.1582 | 1 |
Brugia malayi | glutathione reductase | 0.0037 | 0.004 | 0.0219 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0137 | 0.0569 | 0.5816 |
Brugia malayi | hypothetical protein | 0.0065 | 0.0186 | 0.1142 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Brugia malayi | ecdysteroid receptor | 0.0137 | 0.0569 | 0.3574 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0137 | 0.0569 | 0.0569 |
Echinococcus granulosus | FTZ F1 alpha | 0.0137 | 0.0569 | 0.0569 |
Schistosoma mansoni | jumonji domain containing protein | 0.0085 | 0.0293 | 0.0287 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0072 | 0.0227 | 0.0221 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0132 | 0.054 | 0.0556 |
Brugia malayi | Pre-SET motif family protein | 0.0214 | 0.0974 | 0.6144 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0065 | 0.0186 | 0.1142 |
Brugia malayi | nuclear receptor NHR-88 | 0.0137 | 0.0569 | 0.3574 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0132 | 0.054 | 0.0297 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0137 | 0.0569 | 0.0586 |
Brugia malayi | Bromodomain containing protein | 0.0033 | 0.0016 | 0.0067 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0065 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.014 | 0.1382 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.0328 | 0.1582 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.0328 | 0.1582 | 0.5 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0328 | 0.1582 | 1 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.0328 | 0.1582 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0037 | 0.004 | 0.0219 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0143 | 0.0601 | 0.0595 |
Echinococcus granulosus | geminin | 0.019 | 0.0847 | 0.0847 |
Brugia malayi | nuclear receptor NHR-88 | 0.0065 | 0.0186 | 0.1142 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0227 | 0.2283 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0053 | 0.0047 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0016 | 0.001 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0065 | 0.0186 | 0.0187 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0137 | 0.0569 | 0.5816 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.0053 | 0.0297 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0132 | 0.054 | 0.5 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0065 | 0.0186 | 0.1601 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0038 | 0.0043 | 0.0043 |
Brugia malayi | ecdysone receptor | 0.0065 | 0.0186 | 0.1142 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.0053 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0569 | 0.5816 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0227 | 0.2283 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0137 | 0.0569 | 0.5816 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0128 | 0.0522 | 0.3278 |
Echinococcus multilocularis | geminin | 0.019 | 0.0847 | 0.0875 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0085 | 0.0292 | 0.1634 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0214 | 0.0974 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0085 | 0.0292 | 0.1634 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0137 | 0.0569 | 0.0586 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0143 | 0.0601 | 0.6144 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0569 | 0.5816 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0227 | 0.2283 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0137 | 0.0569 | 0.0569 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0065 | 0.0186 | 0.0186 |
Giardia lamblia | PHD finger protein 15 | 0.0033 | 0.0016 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0137 | 0.0569 | 0.0563 |
Brugia malayi | nuclear hormone receptor | 0.0137 | 0.0569 | 0.3574 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0137 | 0.0569 | 0.0586 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0137 | 0.0569 | 0.3574 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0053 | 0.0047 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0132 | 0.054 | 0.0297 |
Schistosoma mansoni | nuclear hormone receptor | 0.0137 | 0.0569 | 0.0563 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0569 | 0.5816 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0065 | 0.0186 | 0.0186 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0137 | 0.0569 | 0.3574 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.1847 | 0.9617 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0065 | 0.0186 | 0.1142 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0137 | 0.0569 | 0.0586 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.004 | 0.0219 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0137 | 0.0569 | 0.0586 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0072 | 0.0227 | 0.023 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0132 | 0.054 | 0.054 |
Schistosoma mansoni | nuclear hormone receptor | 0.0065 | 0.0186 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0033 | 0.0016 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0033 | 0.0016 | 0.0011 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0227 | 0.1403 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0143 | 0.0601 | 0.0595 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0065 | 0.0186 | 0.1142 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0143 | 0.0601 | 0.0619 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0006 | 0.0006 |
Schistosoma mansoni | nuclear receptor | 0.0065 | 0.0186 | 0.018 |
Onchocerca volvulus | 0.0065 | 0.0186 | 0.1601 | |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0569 | 0.5816 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.0847 | 0.0842 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0065 | 0.0186 | 0.0187 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0085 | 0.0292 | 0.1634 |
Echinococcus multilocularis | peregrin | 0.0033 | 0.0016 | 0.0011 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0033 | 0.0016 | 0.0067 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0137 | 0.0569 | 0.3574 |
Echinococcus granulosus | jumonji domain containing protein | 0.0045 | 0.0084 | 0.0084 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.0847 | 0.0842 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0085 | 0.0292 | 0.1634 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0137 | 0.0569 | 0.0569 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0137 | 0.0569 | 0.5008 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0137 | 0.0569 | 0.0563 |
Brugia malayi | conserved hypotetical protein | 0.0065 | 0.0186 | 0.1142 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0072 | 0.0227 | 0.0227 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0094 | 0.0342 | 0.1959 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0072 | 0.0227 | 0.1403 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0137 | 0.0569 | 0.3574 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0065 | 0.0186 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0569 | 0.5816 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0072 | 0.0227 | 0.0221 |
Brugia malayi | hypothetical protein | 0.0065 | 0.0186 | 0.1142 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.0328 | 0.1582 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0038 | 0.0043 | 0.0039 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0037 | 0.004 | 0.0219 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0072 | 0.0227 | 0.2283 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0132 | 0.054 | 0.054 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0065 | 0.0186 | 0.1859 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0143 | 0.0601 | 0.0601 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0072 | 0.0227 | 0.1403 |
Brugia malayi | steroid hormone receptor | 0.0137 | 0.0569 | 0.3574 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0107 | 0.0409 | 0.0409 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0137 | 0.0569 | 0.0563 |
Echinococcus granulosus | peregrin | 0.0033 | 0.0016 | 0.0016 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0137 | 0.0569 | 0.0563 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0067 | 0.02 | 0.2007 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0045 | 0.0084 | 0.0081 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0137 | 0.0569 | 0.3574 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0137 | 0.0569 | 0.3574 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0039 | 0.0053 | 0.0049 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0137 | 0.0569 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0065 | 0.0186 | 0.1601 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0065 | 0.0186 | 0.0186 |
Brugia malayi | tailless protein | 0.0065 | 0.0186 | 0.1142 |
Plasmodium falciparum | thioredoxin reductase | 0.0037 | 0.004 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0065 | 0.0186 | 0.1859 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0137 | 0.0569 | 0.5816 |
Brugia malayi | nuclear receptor RXR | 0.0072 | 0.0227 | 0.1403 |
Onchocerca volvulus | Alhambra homolog | 0.0033 | 0.0016 | 0.0093 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0328 | 0.1582 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0094 | 0.0342 | 0.1959 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0065 | 0.0186 | 0.0187 |
Onchocerca volvulus | 0.0065 | 0.0186 | 0.1601 | |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0132 | 0.054 | 0.0556 |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.004 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Brugia malayi | jmjC domain containing protein | 0.0107 | 0.0409 | 0.2559 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0137 | 0.0569 | 0.3574 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0137 | 0.0569 | 0.3574 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0128 | 0.0522 | 0.3127 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0016 | 0.0108 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0137 | 0.0569 | 0.3574 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0137 | 0.0569 | 0.3574 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0065 | 0.0186 | 0.0186 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0137 | 0.0569 | 0.3574 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0065 | 0.0186 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.0569 | 0.5816 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.0328 | 0.1582 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0065 | 0.0186 | 0.018 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0137 | 0.0569 | 0.5816 |
Trichomonas vaginalis | set domain proteins, putative | 0.0243 | 0.113 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0227 | 0.2283 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0137 | 0.0569 | 0.5008 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0137 | 0.0569 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0137 | 0.0569 | 0.0563 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0137 | 0.0569 | 0.0569 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0227 | 0.1403 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0186 | 0.1859 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.1919 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.