Detailed information for compound 1030650

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 406.688 | Formula: C17H18Cl3NO4
  • H donors: 2 H acceptors: 2 LogP: 4.72 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)Cc1ccc(c(c1Cl)Cl)Oc1ccc(c(c1)CN)O.Cl
  • InChi: 1S/C17H17Cl2NO4.ClH/c1-2-23-15(22)8-10-3-6-14(17(19)16(10)18)24-12-4-5-13(21)11(7-12)9-20;/h3-7,21H,2,8-9,20H2,1H3;1H
  • InChiKey: HMNMWGCHGDEXIZ-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Leishmania major 4-coumarate:coa ligase-like protein 0.0077 0.0206 0.0379
Loa Loa (eye worm) ICD-1 protein 0.0031 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0039 0.0065 0.0065
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0062 0.006
Schistosoma mansoni hypothetical protein 0.0087 0.0247 0.0247
Giardia lamblia Cathepsin L precursor 0.032 0.1122 0.2843
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0762 0.2787 0.2787
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0031 0.0055
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0031 0.0053
Loa Loa (eye worm) hypothetical protein 0.0442 0.1583 0.1583
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0569 0.0567
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0065 0.012
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0065 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0065 0.0062
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0044 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0062 0.0115
Echinococcus multilocularis thioredoxin glutathione reductase 0.0087 0.0246 0.0244
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0065 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Loa Loa (eye worm) heterochromatin protein 1 0.0076 0.0202 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1401 0.5189 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2679 1 1
Toxoplasma gondii cathepsin CPC2 0.032 0.1122 0.2158
Mycobacterium ulcerans lipase LipD 0.0039 0.0065 0.307
Entamoeba histolytica acyl-coA synthetase, putative 0.0077 0.0206 0.0392
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0031 0.0028
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0287 0.0285
Brugia malayi Cathepsin L-like precursor 0.1401 0.5189 0.5189
Leishmania major basic transcription factor 3a, putative 0.0031 0.0035 0.0062
Entamoeba histolytica hypothetical protein 0.0152 0.0488 0.0937
Entamoeba histolytica cysteine proteinase, putative 0.0762 0.2787 0.5368
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0062 0.0112
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0062 0.0115
Onchocerca volvulus 0.01 0.0294 0.0563
Brugia malayi Papain family cysteine protease containing protein 0.032 0.1122 0.1121
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0062 0.006
Plasmodium vivax vivapain-2 0.1401 0.5189 1
Brugia malayi Bromodomain containing protein 0.008 0.0217 0.0217
Brugia malayi Cathepsin L-like precursor 0.1401 0.5189 0.5189
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0077 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.032 0.1122 0.2158
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0031 0.0053
Trypanosoma cruzi trypanothione reductase, putative 0.0087 0.0244 0.0242
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0062 0.0061
Echinococcus multilocularis cathepsin b 0.2679 1 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0031 0.003
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0065 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0065 0.0064
Mycobacterium tuberculosis Probable dehydrogenase 0.0198 0.0662 0.7713
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0077 0.0206 1
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0065 0.0731
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.1122 0.2158
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0156 0.0154
Echinococcus multilocularis sterol regulatory element binding protein 0.0091 0.0259 0.0257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1401 0.5189 1
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Toxoplasma gondii cathepsin CPC1 0.032 0.1122 0.2158
Echinococcus multilocularis cathepsin L cysteine protease 0.1401 0.5189 0.5188
Trypanosoma cruzi major cysteine proteinase, putative 0.032 0.1122 0.112
Leishmania major hypothetical protein, conserved 0.0039 0.0065 0.0116
Leishmania major trypanothione reductase 0.0087 0.0244 0.045
Entamoeba histolytica cysteine proteinase 1, putative 0.0762 0.2787 0.5368
Schistosoma mansoni microtubule-associated protein tau 0.0747 0.2727 0.2727
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0102 0.0102
Mycobacterium ulcerans hypothetical protein 0.0039 0.0065 0.307
Schistosoma mansoni cathepsin s 0.0442 0.1583 0.1583
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0065 0.012
Plasmodium vivax unspecified product 0.0762 0.2787 0.5368
Echinococcus multilocularis cathepsin L 0.032 0.1122 0.112
Plasmodium vivax vivapain-1 0.0762 0.2787 0.5368
Brugia malayi Niemann-Pick C1 protein precursor 0.0211 0.0713 0.0713
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Toxoplasma gondii cathepsin B 0.105 0.3867 0.7452
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.032 0.1122 0.2158
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0057 0.0133 0.1528
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0089 0.0168
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0031 0.0028
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.0857 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0077 0.0206 0.0379
Trichomonas vaginalis conserved hypothetical protein 0.003 0.003 0.0055
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.022 0.0745 0.8684
Giardia lamblia Dipeptidyl-peptidase I precursor 0.032 0.1122 0.2843
Brugia malayi Papain family cysteine protease containing protein 0.0762 0.2787 0.2786
Plasmodium falciparum serine repeat antigen 6 0.032 0.1122 0.2158
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0206 1
Schistosoma mansoni chromobox protein 0.0076 0.0202 0.0202
Plasmodium falciparum serine repeat antigen 7 0.032 0.1122 0.2158
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0031 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0031 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Plasmodium falciparum serine repeat antigen 9 0.032 0.1122 0.2158
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0054 0.0121 0.1391
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0089 0.0168
Trypanosoma cruzi cysteine peptidase, putative 0.0762 0.2787 0.2785
Echinococcus multilocularis protein patched 0.0091 0.0259 0.0257
Plasmodium falciparum cysteine proteinase falcipain 3 0.1401 0.5189 1
Plasmodium vivax unspecified product 0.0442 0.1583 0.3047
Schistosoma mansoni hypothetical protein 0.0356 0.1256 0.1256
Loa Loa (eye worm) hypothetical protein 0.0442 0.1583 0.1583
Brugia malayi Papain family cysteine protease containing protein 0.0762 0.2787 0.2786
Loa Loa (eye worm) hypothetical protein 0.032 0.1122 0.1122
Trypanosoma brucei transcription factor BTF3, putative 0.0031 0.0035 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0958 0.3524 0.679
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0762 0.2787 0.2787
Leishmania major cathepsin L-like protease 0.1448 0.5366 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.032 0.1122 0.2158
Schistosoma mansoni hypothetical protein 0.0152 0.0488 0.0488
Giardia lamblia Cysteine protease 0.032 0.1122 0.2843
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.105 0.3867 0.7452
Brugia malayi Cathepsin L-like cysteine proteinase 0.0958 0.3524 0.3524
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1401 0.5189 0.5188
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1401 0.5189 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0152 0.0488 0.0486
Brugia malayi fibroinase precursor 0.032 0.1122 0.1121
Brugia malayi Glycosyl hydrolases family 31 protein 0.0173 0.0569 0.0568
Entamoeba histolytica cysteine proteinase, putative 0.1401 0.5189 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0062 0.0115
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0065 0.0065
Brugia malayi Cathepsin L-like precursor 0.1401 0.5189 0.5189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.1122 0.2158
Loa Loa (eye worm) papain family cysteine protease containing protein 0.032 0.1122 0.1122
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0054 0.0121 0.1391
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.032 0.1122 0.2158
Echinococcus multilocularis microtubule associated protein 2 0.0747 0.2727 0.2726
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0062 0.0115
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.011 0.011
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0065 0.012
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.0862 0.0861
Trypanosoma cruzi major cysteine proteinase, putative 0.0367 0.1298 0.1297
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0089 0.0168
Plasmodium vivax glutathione reductase, putative 0.0087 0.0244 0.0466
Onchocerca volvulus 0.0033 0.0043 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.1122 0.2158
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0008 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0088 0.0088
Entamoeba histolytica cysteine proteinase 2 0.0762 0.2787 0.5368
Loa Loa (eye worm) cathepsin B 0.105 0.3867 0.3867
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0039 0.0065 0.0065
Plasmodium falciparum serine repeat antigen 4 0.032 0.1122 0.2158
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.032 0.1122 0.2158
Loa Loa (eye worm) hypothetical protein 0.0034 0.0044 0.0044
Trypanosoma cruzi cysteine protease, putative 0.0762 0.2787 0.2785
Mycobacterium tuberculosis Conserved protein 0.0039 0.0065 0.0731
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0054 0.01
Entamoeba histolytica cysteine protease, putative 0.032 0.1122 0.2158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Brugia malayi PHD-finger family protein 0.0026 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0051 0.011 0.011
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0077 0.0206 1
Treponema pallidum NADH oxidase 0.003 0.0031 0.5
Leishmania major 4-coumarate:coa ligase-like protein 0.0077 0.0206 0.0379
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0065 0.0731
Echinococcus granulosus cathepsin L 0.032 0.1122 0.112
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.032 0.1122 0.2158
Giardia lamblia Cathepsin L precursor 0.032 0.1122 0.2843
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Loa Loa (eye worm) hypothetical protein 0.0039 0.0065 0.0065
Schistosoma mansoni inositol monophosphatase 0.0036 0.0054 0.0054
Echinococcus granulosus geminin 0.0356 0.1256 0.1254
Loa Loa (eye worm) hypothetical protein 0.0077 0.0206 0.0206
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1401 0.5189 1
Giardia lamblia Cathepsin B precursor 0.032 0.1122 0.2843
Plasmodium vivax basic transcription factor 3b, putative 0.0031 0.0035 0.0064
Schistosoma mansoni patched 1 0.0091 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0039 0.0065 0.0065
Echinococcus granulosus expressed conserved protein 0.0199 0.0665 0.0663
Brugia malayi Bromodomain containing protein 0.0041 0.0071 0.007
Echinococcus multilocularis cysteine protease 0.1401 0.5189 0.5188
Entamoeba histolytica cysteine protease, putative 0.032 0.1122 0.2158
Plasmodium falciparum thioredoxin reductase 0.003 0.0031 0.0055
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.105 0.3867 0.3866
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0031 0.0053
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.032 0.1122 0.1122
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0035 0.0064
Mycobacterium ulcerans beta-lactamase 0.0039 0.0065 0.307
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0102 0.0102
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0202 0.0386
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0762 0.2787 0.5368
Leishmania major cathepsin L-like protease 0.1448 0.5366 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0198 0.0662 0.7713
Brugia malayi cahepsin L-like non-peptiedase homolog 0.032 0.1122 0.1121
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.032 0.1122 0.2158
Echinococcus granulosus cathepsin L cysteine protease 0.0762 0.2787 0.2785
Giardia lamblia Dipeptidyl-peptidase I precursor 0.032 0.1122 0.2843
Plasmodium falciparum thioredoxin reductase 0.0087 0.0244 0.0466
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0152 0.0488 0.0486
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0065 0.012
Leishmania major cathepsin L-like protease 0.1448 0.5366 1
Giardia lamblia Cathepsin B precursor 0.032 0.1122 0.2843
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0202 0.0386
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0442 0.1583 0.1583
Echinococcus multilocularis Niemann Pick C1 protein 0.0302 0.1055 0.1053
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0198 0.0662 0.8882
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0762 0.2787 0.2785
Trypanosoma cruzi cysteine proteinase, putative 0.0762 0.2787 0.2785
Entamoeba histolytica hypothetical protein 0.0152 0.0488 0.0937
Loa Loa (eye worm) hypothetical protein 0.2679 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0062 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Onchocerca volvulus 0.0039 0.0065 0.012
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.022 0.0745 1
Toxoplasma gondii ABC1 family protein 0.0039 0.0065 0.012
Loa Loa (eye worm) hypothetical protein 0.032 0.1122 0.1122
Brugia malayi Papain family cysteine protease containing protein 0.032 0.1122 0.1121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Echinococcus granulosus Protein patched homolog 1 0.0091 0.0259 0.0257
Entamoeba histolytica papain family cysteine protease domain containing protein 0.032 0.1122 0.2158
Trypanosoma cruzi cysteine peptidase, putative 0.1401 0.5189 0.5188
Schistosoma mansoni cathepsin F (C01 family) 0.1401 0.5189 0.5189
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Plasmodium falciparum serine repeat antigen 3 0.032 0.1122 0.2158
Giardia lamblia Cathepsin L precursor 0.032 0.1122 0.2843
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0065 0.0062
Brugia malayi beta-lactamase family protein 0.0039 0.0065 0.0064
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0062 0.0115
Echinococcus multilocularis chromobox protein 1 0.0076 0.0202 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Echinococcus granulosus chromobox protein 1 0.0076 0.0202 0.02
Echinococcus multilocularis chromobox protein 1 0.0076 0.0202 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.032 0.1122 0.2158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0031 0.0028
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0287 0.0286
Schistosoma mansoni hypothetical protein 0.0087 0.0247 0.0247
Toxoplasma gondii NAC domain-containing protein 0.0031 0.0035 0.0064
Leishmania major cathepsin L-like protease 0.1401 0.5189 0.967
Echinococcus multilocularis Niemann Pick C1 protein 0.0211 0.0713 0.0711
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0002 0.0002
Giardia lamblia Cathepsin L-like protease 0.032 0.1122 0.2843
Giardia lamblia Cysteine protease 0.032 0.1122 0.2843
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.1401 0.5189 0.967
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0031 0.0053
Entamoeba histolytica hypothetical protein 0.0152 0.0488 0.0937
Brugia malayi cathepsin Z-like cysteine proteinase 0.032 0.1122 0.1121
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0077 0.0144
Echinococcus granulosus cathepsin L 0.0762 0.2787 0.2785
Loa Loa (eye worm) hypothetical protein 0.1401 0.5189 0.5189
Entamoeba histolytica hypothetical protein 0.032 0.1122 0.2158
Schistosoma mansoni hypothetical protein 0.0034 0.0044 0.0044
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0062 0.0115
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0287 0.0285
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0057 0.0133 1
Giardia lamblia Cathepsin L precursor 0.032 0.1122 0.2843
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0054 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0287 0.0287
Giardia lamblia Cathepsin B precursor 0.105 0.3867 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1401 0.5189 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0287 0.0285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.1122 0.2158
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0035 0.0064
Loa Loa (eye worm) hypothetical protein 0.032 0.1122 0.1122
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0031 0.0053
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0054 0.0097
Brugia malayi cathepsin L precursor 0.032 0.1122 0.1121
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0062 0.0115
Echinococcus multilocularis transcription factor btf3 0.0031 0.0035 0.0033
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.032 0.1122 0.2158
Toxoplasma gondii cathepsin CPL 0.1401 0.5189 1
Loa Loa (eye worm) hypothetical protein 0.0958 0.3524 0.3524
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0031 0.0028
Mycobacterium tuberculosis Conserved protein 0.0039 0.0065 0.0731
Mycobacterium leprae Probable lipase LipE 0.0039 0.0065 0.0841
Plasmodium vivax vivapain-2 0.1401 0.5189 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0031 0.0055
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.1122 0.1122
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2679 1 1
Giardia lamblia Hypothetical protein 0.032 0.1122 0.2843
Loa Loa (eye worm) glutathione reductase 0.0087 0.0244 0.0244
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0054 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.1122 0.2158
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0031 0.1397
Loa Loa (eye worm) hypothetical protein 0.0057 0.0133 0.0133
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Entamoeba histolytica cysteine proteinase, putative 0.0762 0.2787 0.5368
Plasmodium falciparum serine repeat antigen 1 0.032 0.1122 0.2158
Brugia malayi Thioredoxin reductase 0.0087 0.0244 0.0243
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0287 0.0287
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.022 0.0745 0.8684
Brugia malayi beta-NAC-like protein 0.0031 0.0035 0.0035
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0173 0.0569 0.0569
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.0862 0.0861
Brugia malayi cathepsin Z-like cysteine proteinase 0.032 0.1122 0.1121
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.032 0.1122 0.2843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Loa Loa (eye worm) hypothetical protein 0.0958 0.3524 0.3524
Entamoeba histolytica cysteine protease, putative 0.032 0.1122 0.2158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0031 0.0028
Giardia lamblia Cathepsin B precursor 0.032 0.1122 0.2843
Brugia malayi Cathepsin L-like precursor 0.1401 0.5189 0.5189
Trypanosoma brucei cysteine peptidase C (CPC) 0.105 0.3867 0.7206
Brugia malayi AMP-binding enzyme family protein 0.0077 0.0206 0.0205
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0054 0.01
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.032 0.1122 0.1122
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0031 0.1397
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0215 0.0725 0.0725
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0031 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0031 0.0028
Plasmodium falciparum serine repeat antigen 8 0.032 0.1122 0.2158
Loa Loa (eye worm) hypothetical protein 0.0057 0.0133 0.0133
Brugia malayi cathepsin F-like cysteine proteinase 0.032 0.1122 0.1121
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0077 0.0206 0.2741
Echinococcus multilocularis cathepsin L cysteine protease 0.1401 0.5189 0.5188
Toxoplasma gondii thioredoxin reductase 0.0087 0.0244 0.0466
Mycobacterium tuberculosis Conserved protein 0.0039 0.0065 0.0731
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Loa Loa (eye worm) oxidoreductase 0.0022 0.0002 0.0002
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Echinococcus multilocularis cysteine protease 0.1401 0.5189 0.5188
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0077 0.0144
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.032 0.1122 0.1122
Brugia malayi cathepsin L-like cysteine proteinase 0.032 0.1122 0.1121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0762 0.2787 0.5191
Echinococcus multilocularis cathepsin L 0.0762 0.2787 0.2785
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1401 0.5189 0.5189
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0008 0.0005
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.032 0.1122 0.1122
Plasmodium vivax acyl-CoA synthetase, putative 0.0057 0.0133 0.0252
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2679 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.032 0.1122 0.2158
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0031 0.0028
Schistosoma mansoni hypothetical protein 0.0087 0.0247 0.0247
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0062 0.0115
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1401 0.5189 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0054 0.0052
Brugia malayi Cathepsin L-like precursor 0.0442 0.1583 0.1582
Echinococcus granulosus lysosomal alpha glucosidase 0.0173 0.0569 0.0567
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.1401 0.5189 1
Entamoeba histolytica cysteine proteinase, putative 0.0762 0.2787 0.5368
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.004 0.0442
Entamoeba histolytica cysteine protease, putative 0.032 0.1122 0.2158
Trypanosoma cruzi transcription factor btf3, putative 0.0031 0.0035 0.0033
Brugia malayi chromobox protein homolog 3 0.0042 0.0077 0.0076
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.032 0.1122 0.2158
Entamoeba histolytica cysteine proteinase, putative 0.0958 0.3524 0.679
Loa Loa (eye worm) ctsf protein 0.1401 0.5189 0.5189
Plasmodium vivax serine-repeat antigen (SERA) 0.032 0.1122 0.2158
Brugia malayi hypothetical protein 0.0152 0.0488 0.0487
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.032 0.1122 0.2158
Entamoeba histolytica hypothetical protein 0.0031 0.0035 0.0064
Loa Loa (eye worm) hypothetical protein 0.0057 0.0133 0.0133
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0062 0.0115
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0031 0.0055
Echinococcus granulosus cathepsin l1 0.0958 0.3524 0.3523
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0031 0.0053
Echinococcus granulosus sterol regulatory element binding protein 0.0091 0.0259 0.0257
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0198 0.0662 0.7713
Echinococcus granulosus Niemann Pick C1 protein 0.0211 0.0713 0.0711
Loa Loa (eye worm) hypothetical protein 0.0077 0.0206 0.0206
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0206 1
Schistosoma mansoni chromobox protein 0.0076 0.0202 0.0202
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1401 0.5189 0.5188
Brugia malayi hypothetical protein 0.0251 0.0862 0.0862
Giardia lamblia Cathepsin L precursor 0.032 0.1122 0.2843
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0031 0.0053
Onchocerca volvulus Cathepsin L homolog 0.032 0.1122 0.2158
Echinococcus granulosus cathepsin L cysteine proteinase 0.1401 0.5189 0.5188
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.032 0.1122 0.2158
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1401 0.5189 1
Brugia malayi Papain family cysteine protease containing protein 0.1401 0.5189 0.5189
Plasmodium vivax thioredoxin reductase, putative 0.0087 0.0244 0.0466
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.032 0.1122 0.2158
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1401 0.5189 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.1401 0.5189 0.5188
Trypanosoma cruzi cysteine proteinase, putative 0.0762 0.2787 0.2785
Giardia lamblia Encystation-specific protease 0.032 0.1122 0.2843
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0031 0.0055
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0077 0.0206 0.2741
Giardia lamblia Cysteine protease 0.032 0.1122 0.2843
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0039 0.0065 0.0065
Leishmania major cathepsin L-like protease 0.1401 0.5189 0.967
Schistosoma mansoni cathepsin C 0.032 0.1122 0.1122
Brugia malayi Papain family cysteine protease containing protein 0.032 0.1122 0.1121
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0065 0.0062
Loa Loa (eye worm) fibroinase 0.1401 0.5189 0.5189
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0211 0.0713 0.1371
Onchocerca volvulus 0.1401 0.5189 1
Plasmodium falciparum glutathione reductase 0.0087 0.0244 0.0466
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0054 0.01
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0762 0.2787 0.2787
Schistosoma mansoni survival motor neuron protein 0.0051 0.011 0.011
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0002 0.0002
Onchocerca volvulus 0.1401 0.5189 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0156 0.0154
Schistosoma mansoni hypothetical protein 0.0356 0.1256 0.1256
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Brugia malayi Cathepsin L-like precursor 0.1401 0.5189 0.5189
Onchocerca volvulus 0.032 0.1122 0.2158
Echinococcus granulosus cathepsin b 0.2679 1 1
Onchocerca volvulus 0.1401 0.5189 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0065 0.0731
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0762 0.2787 0.5368
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0065 0.0731
Trypanosoma cruzi cysteine peptidase, putative 0.1448 0.5366 0.5365
Onchocerca volvulus 0.0051 0.011 0.0208
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1741 0.647 0.647
Onchocerca volvulus 0.1401 0.5189 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0762 0.2787 0.5191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1401 0.5189 1
Mycobacterium ulcerans hypothetical protein 0.0077 0.0206 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0031 0.1397
Echinococcus granulosus cathepsin b 0.2679 1 1
Echinococcus granulosus microtubule associated protein 2 0.0747 0.2727 0.2726
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0198 0.0662 0.7713
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0065 0.0731
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0065 0.307
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0065 0.0731
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0077 0.0206 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0062 0.006
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.032 0.1122 0.2158
Trypanosoma cruzi cysteine peptidase, putative 0.0442 0.1583 0.1581
Entamoeba histolytica cysteine protease, putative 0.1401 0.5189 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1401 0.5189 1
Onchocerca volvulus 0.1401 0.5189 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.032 0.1122 0.1122
Onchocerca volvulus 0.0958 0.3524 0.679
Brugia malayi AMP-binding enzyme family protein 0.0077 0.0206 0.0205
Giardia lamblia Cathepsin B precursor 0.032 0.1122 0.2843
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0054 0.0097
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0031 0.0031
Plasmodium falciparum cysteine proteinase falcipain 1 0.0762 0.2787 0.5368
Onchocerca volvulus 0.1401 0.5189 1
Loa Loa (eye worm) thioredoxin reductase 0.0087 0.0244 0.0244
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0091 0.0259 0.0259
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0031 0.0333
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.105 0.3867 0.3867
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0054 0.0121 0.1391
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0054 0.0052
Giardia lamblia Cathepsin B precursor 0.105 0.3867 1
Trypanosoma cruzi cruzipain precursor, putative 0.0442 0.1583 0.1581
Leishmania major cathepsin L-like protease 0.1401 0.5189 0.967
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0065 0.0731
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.032 0.1122 0.2158
Entamoeba histolytica cysteine protease, putative 0.032 0.1122 0.2158
Trypanosoma brucei trypanothione reductase 0.0087 0.0244 0.045
Trypanosoma cruzi cruzipain precursor, putative 0.1448 0.5366 0.5365
Plasmodium vivax serine-repeat antigen (SERA), putative 0.032 0.1122 0.2158
Onchocerca volvulus 0.0039 0.0065 0.012
Onchocerca volvulus 0.0039 0.0065 0.012
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0442 0.1583 0.1582
Brugia malayi AMP-binding enzyme family protein 0.0077 0.0206 0.0205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0958 0.3524 0.679
Echinococcus multilocularis cathepsin b 0.2679 1 1
Schistosoma mansoni cathepsin S (C01 family) 0.032 0.1122 0.1122
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0054 0.01
Mycobacterium tuberculosis Probable reductase 0.0198 0.0662 0.7713
Plasmodium falciparum serine repeat antigen 5 0.032 0.1122 0.2158
Loa Loa (eye worm) hypothetical protein 0.0211 0.0713 0.0713
Giardia lamblia Hypothetical protein 0.032 0.1122 0.2843
Plasmodium falciparum basic transcription factor 3b, putative 0.0031 0.0035 0.0064
Plasmodium vivax serine-repeat antigen (SERA) 0.032 0.1122 0.2158
Echinococcus multilocularis geminin 0.0356 0.1256 0.1254
Loa Loa (eye worm) hypothetical protein 0.0251 0.0862 0.0862
Plasmodium vivax serine-repeat antigen (SERA), putative 0.032 0.1122 0.2158
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.032 0.1122 0.1122
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Entamoeba histolytica papain family cysteine protease domain containing protein 0.032 0.1122 0.2158
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0002
Schistosoma mansoni transcription factor LCR-F1 0.0152 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0057 0.0133 0.0133
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0065 0.0116
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1401 0.5189 1
Giardia lamblia Cathepsin B precursor 0.105 0.3867 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.0958 0.3524 0.3524
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.032 0.1122 0.2158
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0259 0.0495
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1401 0.5189 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0336 0.0336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0087 0.0244 0.2825
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Entamoeba histolytica transcription factor BTF3, putative 0.0031 0.0035 0.0064
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2679 1 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0065 0.307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.032 0.1122 0.2158
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0062 0.0062
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0031 0.0055
Mycobacterium ulcerans acyl-CoA synthetase 0.0077 0.0206 1
Schistosoma mansoni alpha glucosidase 0.0038 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0091 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0043 0.008 0.008
Schistosoma mansoni bromodomain containing protein 0.0067 0.017 0.017
Echinococcus granulosus chromobox protein 1 0.0076 0.0202 0.02
Onchocerca volvulus 0.1401 0.5189 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.032 0.1122 0.1122
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0077 0.0206 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0062 0.0115
Schistosoma mansoni cathepsin F (C01 family) 0.0958 0.3524 0.3524
Trypanosoma cruzi cysteine peptidase, putative 0.1448 0.5366 0.5365
Toxoplasma gondii preprocathepsin c precursor, putative 0.032 0.1122 0.2158
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0077 0.0206 0.238
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0061 0.0059
Entamoeba histolytica cysteine protease, putative 0.032 0.1122 0.2158
Onchocerca volvulus 0.0077 0.0206 0.0392
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.1122 0.1122
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0031 0.0028
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0054 0.0052
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0061 0.0059
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.004 0.0509
Entamoeba histolytica acyl-CoA synthetase, putative 0.0077 0.0206 0.0392
Echinococcus multilocularis protein dispatched 1 0.0104 0.0307 0.0305
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.1122 0.1122
Plasmodium falciparum acyl-CoA synthetase 0.0057 0.0133 0.0252
Schistosoma mansoni cathepsin B (C01 family) 0.032 0.1122 0.1122
Loa Loa (eye worm) hypothetical protein 0.032 0.1122 0.1122
Loa Loa (eye worm) hypothetical protein 0.0049 0.0102 0.0102
Plasmodium vivax unspecified product 0.032 0.1122 0.2158
Loa Loa (eye worm) hypothetical protein 0.0077 0.0206 0.0206
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0054 0.2561
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2679 1 1
Brugia malayi CHE-14 protein 0.0091 0.0259 0.0258
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1401 0.5189 0.5189
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0035 0.0064
Echinococcus granulosus thioredoxin glutathione reductase 0.0087 0.0246 0.0244
Loa Loa (eye worm) hypothetical protein 0.0442 0.1583 0.1583
Loa Loa (eye worm) cysteine protease 0.1401 0.5189 0.5189
Loa Loa (eye worm) hypothetical protein 0.0057 0.0133 0.0133
Onchocerca volvulus Cathepsin F homolog 0.1401 0.5189 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.032 0.1122 0.1122
Loa Loa (eye worm) hypothetical protein 0.0958 0.3524 0.3524
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0062 0.0115
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.105 0.3867 0.7206
Schistosoma mansoni cathepsin F (C01 family) 0.1401 0.5189 0.5189
Loa Loa (eye worm) hypothetical protein 0.0075 0.02 0.02
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.032 0.1122 0.2158
Leishmania major cysteine peptidase A (CPA) 0.1401 0.5189 0.967
Echinococcus granulosus transcription factor btf3 0.0031 0.0035 0.0033
Giardia lamblia Cysteine protease 0.032 0.1122 0.2843
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0031 0.0053
Brugia malayi Cathepsin L-like precursor 0.0958 0.3524 0.3524
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.032 0.1122 0.2158
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0031 0.0055
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0062 0.006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0033 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.032 0.1122 0.2158
Schistosoma mansoni inositol monophosphatase 0.0036 0.0054 0.0054
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.032 0.1122 0.2158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.032 0.1122 0.2158
Schistosoma mansoni alpha-glucosidase 0.0149 0.0478 0.0478
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0002 0.0002
Echinococcus granulosus cathepsin l1 0.1401 0.5189 0.5188
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0077 0.0206 0.238
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.032 0.1122 0.2158
Echinococcus multilocularis expressed conserved protein 0.0199 0.0665 0.0663
Plasmodium falciparum serine repeat antigen 2 0.032 0.1122 0.2158
Brugia malayi Heterochromatin protein 1 0.0076 0.0202 0.0202
Plasmodium falciparum glutathione reductase 0.003 0.0031 0.0055
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1401 0.5189 1
Trichomonas vaginalis esterase, putative 0.0039 0.0065 0.012
Onchocerca volvulus Cathepsin L homolog 0.1401 0.5189 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0031 0.0028
Giardia lamblia Cathepsin B precursor 0.032 0.1122 0.2843
Entamoeba histolytica cysteine proteinase, putative 0.0762 0.2787 0.5368
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Trypanosoma cruzi transcription factor btf3, putative 0.0031 0.0035 0.0033
Entamoeba histolytica acyl-CoA synthetase, putative 0.0077 0.0206 0.0392
Entamoeba histolytica cysteine protease, putative 0.0762 0.2787 0.5368
Trypanosoma cruzi cysteine peptidase, putative 0.1448 0.5366 0.5365
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0002 0.0002
Echinococcus granulosus cysteine protease 0.0762 0.2787 0.2785
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0054 0.0121 0.1391
Giardia lamblia Cathepsin L-like protease 0.032 0.1122 0.2843
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Brugia malayi Inositol-1 0.0036 0.0054 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1448 0.5366 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0057 0.0133 0.6421
Entamoeba histolytica hypothetical protein 0.0152 0.0488 0.0937
Loa Loa (eye worm) hypothetical protein 0.0042 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0087 0.0247 0.0247
Giardia lamblia Dipeptidyl-peptidase I precursor 0.032 0.1122 0.2843
Brugia malayi Cathepsin L-like precursor 0.1401 0.5189 0.5189
Loa Loa (eye worm) inositol-1 0.0036 0.0054 0.0054
Schistosoma mansoni transcription factor btf3 0.0031 0.0035 0.0035
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.1122 0.1122
Loa Loa (eye worm) beta-lactamase 0.0039 0.0065 0.0065
Plasmodium vivax vivapain-3 0.0762 0.2787 0.5368
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1005 0.3701 0.37
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.032 0.1122 0.1122
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0287 0.0285
Loa Loa (eye worm) hypothetical protein 0.0041 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.032 0.1122 0.2158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Trypanosoma brucei glucosidase, putative 0.0038 0.0062 0.0112
Onchocerca volvulus Cathepsin L homolog 0.1401 0.5189 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0569 0.0567
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0065 0.012
Echinococcus granulosus Niemann Pick C1 protein 0.0302 0.1055 0.1053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1401 0.5189 1
Brugia malayi beta-lactamase family protein 0.0039 0.0065 0.0064
Schistosoma mansoni alpha-glucosidase 0.0149 0.0478 0.0478
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0287 0.0287
Brugia malayi cathepsin L-like precursor 0.0958 0.3524 0.3524
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0054 0.0052
Brugia malayi glutathione reductase 0.0087 0.0244 0.0243
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0198 0.0662 0.7713
Mycobacterium tuberculosis Probable oxidoreductase 0.022 0.0745 0.8684
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0031 0.0055
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0065 0.0841
Brugia malayi beta-lactamase 0.0039 0.0065 0.0064
Brugia malayi cathepsin F-like cysteine proteinase 0.0442 0.1583 0.1582
Leishmania major cathepsin L-like protease 0.1401 0.5189 0.967
Trichomonas vaginalis conserved hypothetical protein 0.003 0.003 0.0055
Giardia lamblia Cathepsin L precursor 0.032 0.1122 0.2843

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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