Detailed information for compound 1031111

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 361.437 | Formula: C22H23N3O2
  • H donors: 1 H acceptors: 2 LogP: 3.17 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1c(cnc2c1cccc2)C(=O)NC1CCN(C1)Cc1ccccc1
  • InChi: 1S/C22H23N3O2/c1-27-21-18-9-5-6-10-20(18)23-13-19(21)22(26)24-17-11-12-25(15-17)14-16-7-3-2-4-8-16/h2-10,13,17H,11-12,14-15H2,1H3,(H,24,26)
  • InChiKey: NDNAGLVRQAPTRG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni tubulin subunit epsilon 0.0088 0.0843 0.1137
Onchocerca volvulus 0.0116 0.1152 0.4802
Echinococcus multilocularis tubulin subunit TubB 0.0088 0.0843 0.0843
Toxoplasma gondii cathepsin CPL 0.0013 0.0016 0.0194
Brugia malayi Receptor family ligand binding region containing protein 0.0039 0.0303 0.0408
Leishmania major alpha tubulin 0.0088 0.0843 1
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0116 0.1152 0.1152
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0042 0.0337 0.3874
Trypanosoma cruzi kinesin, putative 0.0042 0.0337 0.3874
Echinococcus granulosus tubulin alpha chain 0.0088 0.0843 0.1137
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0174 0.2064
Onchocerca volvulus 0.005 0.0425 0.177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Leishmania major beta tubulin 0.0088 0.0843 1
Brugia malayi tubulin alpha-2 chain 0.0088 0.0843 0.1137
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0148 0.1496 0.2018
Onchocerca volvulus 0.0013 0.0016 0.0068
Trypanosoma brucei kinesin, putative 0.0042 0.0337 0.3746
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0328 0.2005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.045 0.0607
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0038 0.0298 0.0928
Loa Loa (eye worm) calpain family protein 1 0.014 0.1417 0.1912
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0016 0.0022
Echinococcus granulosus calpain 5 0.0042 0.0337 0.0454
Trypanosoma cruzi cysteine peptidase, putative 0.0048 0.0402 0.4667
Trichomonas vaginalis tubulin epsilon chain, putative 0.0088 0.0843 0.2628
Loa Loa (eye worm) hypothetical protein 0.0039 0.0303 0.0408
Schistosoma mansoni thyroid hormone receptor 0.0016 0.0049 0.0066
Leishmania major alpha tubulin 0.0088 0.0843 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0518 0.0698
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0039 0.0303 0.1262
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.1054 0.1422
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0039 0.0303 0.0408
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0425 0.1323
Toxoplasma gondii beta tubulin 0.0088 0.0843 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0049 0.042 0.4877
Echinococcus multilocularis mitogen activated protein kinase 3 0.0049 0.042 0.042
Onchocerca volvulus 0.0016 0.0049 0.0205
Echinococcus multilocularis cathepsin L cysteine protease 0.0013 0.0016 0.0016
Echinococcus multilocularis tubulin alpha 3 chain 0.0088 0.0843 0.0843
Echinococcus granulosus Tubulin alpha 1 chain 0.0088 0.0843 0.1137
Echinococcus granulosus nmda type glutamate receptor 0.0039 0.0303 0.0408
Brugia malayi hypothetical protein 0.0116 0.1152 0.1554
Toxoplasma gondii beta-1 tubulin, putative 0.0088 0.0843 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0088 0.0843 0.2628
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0066
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0116 0.1152 0.1554
Brugia malayi PHD-finger family protein 0.0026 0.0161 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Echinococcus multilocularis peregrin 0.0031 0.0213 0.0213
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0116 0.1152 0.4117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0032 0.01
Leishmania major alpha tubulin 0.0088 0.0843 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0016 0.0049 0.0066
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.045 0.045
Onchocerca volvulus 0.023 0.2399 1
Echinococcus multilocularis calpain A 0.0148 0.1496 0.1496
Loa Loa (eye worm) hypothetical protein 0.005 0.0425 0.0573
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0016 0.0049 0.0066
Echinococcus granulosus glutamate receptor 2 0.0039 0.0303 0.0408
Echinococcus multilocularis tubulin alpha chain 0.0088 0.0843 0.0843
Echinococcus multilocularis tubulin subunit beta 0.0088 0.0843 0.0843
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0328 0.0255
Brugia malayi calpain family protein 1 0.014 0.1417 0.1912
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0328 0.3774
Schistosoma mansoni hypothetical protein 0.0015 0.0041 0.0056
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0116 0.1152 0.1554
Schistosoma mansoni tubulin subunit delta 0.0038 0.0298 0.0402
Schistosoma mansoni chromobox protein 0.0067 0.0618 0.0834
Mycobacterium ulcerans lipase LipD 0.0041 0.0328 0.2005
Schistosoma mansoni tubulin subunit beta 0.0088 0.0843 0.1137
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0016 0.0022
Echinococcus multilocularis beta tubulin 0.0088 0.0843 0.0843
Echinococcus multilocularis glutamate receptor 2 0.0039 0.0303 0.0303
Echinococcus granulosus cathepsin l1 0.0013 0.0016 0.0022
Trichomonas vaginalis tubulin beta chain, putative 0.0088 0.0843 0.2628
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0016 0.0051
Loa Loa (eye worm) hypothetical protein 0.0116 0.1152 0.1554
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.2094 0.2825
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0016 0.0049 0.0066
Echinococcus multilocularis tubulin alpha 0.0088 0.0843 0.0843
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0385 0.052
Echinococcus granulosus chromobox protein 1 0.0067 0.0618 0.0834
Echinococcus granulosus peregrin 0.0031 0.0213 0.0288
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0344 0.3653 0.3653
Schistosoma mansoni RAR-like nuclear receptor 0.0016 0.0049 0.0066
Trypanosoma cruzi zeta tubulin, putative 0.0038 0.0298 0.3402
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0016 0.0051
Schistosoma mansoni cpg binding protein 0.0031 0.0221 0.0299
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0016 0.0049 0.0066
Echinococcus multilocularis Tubulin alpha 1 chain 0.0088 0.0843 0.0843
Echinococcus multilocularis cysteine protease 0.0013 0.0016 0.0016
Echinococcus multilocularis para nitrobenzyl esterase 0.0116 0.1152 0.1152
Schistosoma mansoni hypothetical protein 0.005 0.0423 0.0571
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Leishmania major beta tubulin 0.0088 0.0843 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0042 0.0337 0.3874
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0455 0.0614
Mycobacterium tuberculosis Carboxylesterase LipT 0.0116 0.1152 0.4117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0383 0.0517
Echinococcus granulosus metabotropic glutamate receptor 5 0.0506 0.5425 0.732
Leishmania major delta tubulin, putative 0.0038 0.0298 0.3402
Trypanosoma brucei zeta tubulin, putative 0.0038 0.0298 0.3264
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.0892 0.1203
Echinococcus multilocularis tubulin alpha 1C chain 0.0088 0.0843 0.0843
Schistosoma mansoni tubulin subunit alpha 0.0038 0.0298 0.0402
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0193 0.1992 0.8304
Toxoplasma gondii alpha tubulin TUBA1 0.0088 0.0843 1
Echinococcus granulosus tubulin subunit TubB 0.0088 0.0843 0.1137
Trypanosoma brucei alpha tubulin 0.0088 0.0843 1
Leishmania major epsilon tubulin, putative 0.0088 0.0843 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0298 0.0402
Echinococcus multilocularis FTZ F1 alpha 0.0016 0.0049 0.0049
Plasmodium vivax delta tubulin, putative 0.0038 0.0298 0.353
Brugia malayi Carboxylesterase family protein 0.0688 0.7412 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0409 0.0552
Brugia malayi tubulin alpha chain - mouse 0.0088 0.0843 0.1137
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0328 0.3644
Giardia lamblia Gamma tubulin 0.0088 0.0843 0.255
Loa Loa (eye worm) hypothetical protein 0.0116 0.1152 0.1554
Echinococcus multilocularis carboxylesterase 5A 0.0688 0.7412 0.7412
Echinococcus multilocularis tubulin gamma 1 chain 0.0088 0.0843 0.0843
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0423 0.0571
Schistosoma mansoni tyrosine kinase 0.0039 0.0303 0.0408
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0067 0.0091
Trichomonas vaginalis tubulin beta chain, putative 0.0088 0.0843 0.2628
Trypanosoma brucei beta tubulin 0.0088 0.0843 1
Onchocerca volvulus 0.0011 0.000000013265 0.000000055302
Leishmania major beta tubulin 0.0088 0.0843 1
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0174 0.2064
Echinococcus multilocularis beta tubulin 0.0088 0.0843 0.0843
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0028 0.0182 0.0568
Trypanosoma cruzi epsilon tubulin, putative 0.0088 0.0843 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0088 0.0843 0.1137
Trypanosoma brucei epsilon tubulin 0.0088 0.0843 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0182 0.2007
Trichomonas vaginalis tubulin beta chain, putative 0.0088 0.0843 0.2628
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0016 0.0049 0.0066
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0291 0.0393
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0011 0.0011
Loa Loa (eye worm) alpha-tubulin 0.0088 0.0843 0.1137
Brugia malayi Cathepsin L-like precursor 0.0013 0.0016 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0016 0.0049 0.0066
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0618 0.0834
Trichomonas vaginalis spcc417.12 protein, putative 0.0116 0.1152 0.359
Loa Loa (eye worm) hypothetical protein 0.0038 0.0293 0.0396
Loa Loa (eye worm) carboxylesterase 0.0116 0.1152 0.1554
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.006 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.3209 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Schistosoma mansoni calpain-7 (C02 family) 0.0044 0.0361 0.0487
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0016 0.0049 0.0066
Brugia malayi Tubulin beta-1 chain 0.0088 0.0843 0.1137
Trypanosoma brucei zeta tubulin 0.0038 0.0298 0.3264
Loa Loa (eye worm) calpain family protein 1 0.0099 0.0959 0.1294
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0291 0.0393
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0455 0.0614
Loa Loa (eye worm) alpha-tubulin isotype 2 0.005 0.0425 0.0573
Brugia malayi hypothetical protein 0.014 0.1408 0.19
Mycobacterium ulcerans carboxylesterase, LipT 0.0116 0.1152 0.7597
Trypanosoma cruzi extracellular receptor, putative 0.0039 0.0303 0.3463
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Loa Loa (eye worm) hypothetical protein 0.0116 0.1152 0.1554
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0328 0.0443
Giardia lamblia Delta tubulin 0.0038 0.0298 0.0833
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0174 0.1907
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.3209 1
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0385 0.0385
Schistosoma mansoni tubulin subunit alpha 0.0088 0.0843 0.1137
Entamoeba histolytica tubulin alpha-1 chain 0.0088 0.0843 0.2628
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0024
Leishmania major alpha tubulin 0.0088 0.0843 1
Trypanosoma brucei beta tubulin 0.0088 0.0843 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0042 0.0337 0.3874
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0042 0.0337 0.3874
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0423 0.0571
Trichomonas vaginalis tubulin gamma chain, putative 0.0088 0.0843 0.2628
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.3209 1
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0039 0.0303 0.0408
Echinococcus granulosus GPCR family 2 0.005 0.0423 0.0571
Echinococcus multilocularis BC026374 protein (S09 family) 0.0116 0.1152 0.1152
Trypanosoma cruzi kinesin, putative 0.0042 0.0337 0.3874
Echinococcus multilocularis ecdysone induced protein 78C 0.0016 0.0049 0.0049
Echinococcus granulosus calpain A 0.0042 0.0337 0.0454
Schistosoma mansoni tubulin subunit alpha 0.0088 0.0843 0.1137
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0042 0.0337 0.3874
Brugia malayi Bromodomain containing protein 0.0074 0.0692 0.0934
Plasmodium vivax tubulin beta chain, putative 0.0088 0.0843 1
Echinococcus granulosus carboxylesterase 5A 0.0688 0.7412 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0016 0.0022
Brugia malayi Tubulin gamma chain 0.0088 0.0843 0.1137
Echinococcus granulosus tubulin alpha 1C chain 0.0088 0.0843 0.1137
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0443
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0425 0.1323
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0013 0.0016 0.0016
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0014 0.0033 0.0205
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0105 0.1034 0.1395
Plasmodium vivax SET domain protein, putative 0.003 0.0202 0.24
Loa Loa (eye worm) hypothetical protein 0.014 0.1417 0.1912
Loa Loa (eye worm) hypothetical protein 0.0157 0.1598 0.2156
Trypanosoma cruzi beta tubulin, putative 0.0088 0.0843 1
Onchocerca volvulus Huntingtin homolog 0.014 0.1408 0.587
Echinococcus multilocularis cysteine protease 0.0013 0.0016 0.0016
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0016 0.0049 0.0066
Leishmania major hypothetical protein, conserved 0.0015 0.0041 0.0302
Brugia malayi beta-lactamase 0.0041 0.0328 0.0443
Echinococcus multilocularis tubulin beta 1 chain 0.0088 0.0843 0.0843
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.042 0.1308
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0033 0.0395
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0039 0.0303 0.0303
Schistosoma mansoni tubulin subunit beta 0.0088 0.0843 0.1137
Trypanosoma cruzi cysteine peptidase, putative 0.0048 0.0402 0.4667
Trypanosoma brucei tubulin delta chain 0.0038 0.0298 0.3264
Brugia malayi PHD-finger family protein 0.0028 0.0188 0.0254
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0069 0.0215
Echinococcus granulosus para nitrobenzyl esterase 0.0116 0.1152 0.1554
Leishmania major zeta tubulin, putative 0.0038 0.0298 0.3402
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.006 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.042 0.4877
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0028 0.0182 0.0182
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0506 0.5425 0.5425
Loa Loa (eye worm) hypothetical protein 0.0028 0.0182 0.0246
Loa Loa (eye worm) tubulin alpha chain 0.0088 0.0843 0.1137
Brugia malayi calpain family protein 1 0.014 0.1417 0.1912
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0016 0.0049 0.0066
Echinococcus multilocularis acetylcholinesterase 0.0688 0.7412 0.7412
Onchocerca volvulus Bile acid receptor homolog 0.0016 0.0049 0.0205
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.006 0.0081
Loa Loa (eye worm) tubulin beta-2A chain 0.0088 0.0843 0.1137
Loa Loa (eye worm) hypothetical protein 0.0193 0.1992 0.2687
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0373 0.3961 0.5344
Schistosoma mansoni tubulin subunit beta 0.0088 0.0843 0.1137
Echinococcus granulosus calpain 7 C02 family 0.0042 0.0337 0.0454
Brugia malayi calpain 7 0.0042 0.0337 0.0454
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0188 0.0188
Schistosoma mansoni tubulin subunit gamma 0.0088 0.0843 0.1137
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.014 0.1417 0.1912
Schistosoma mansoni thyroid hormone receptor 0.0016 0.0049 0.0066
Echinococcus granulosus acetylcholinesterase 0.0688 0.7412 1
Echinococcus multilocularis cpg binding protein 0.0031 0.0221 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Schistosoma mansoni steroid hormone receptor ad4bp 0.0016 0.0049 0.0066
Mycobacterium tuberculosis Cell division protein FtsZ 0.0038 0.0298 0.0973
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0185 0.1904 0.2569
Plasmodium vivax tubulin epsilon chain, putative 0.0088 0.0843 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0042 0.0337 0.3746
Loa Loa (eye worm) hypothetical protein 0.0105 0.1034 0.1395
Trypanosoma brucei alpha tubulin 0.0088 0.0843 1
Loa Loa (eye worm) hypothetical protein 0.014 0.1408 0.19
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0042 0.0337 0.3874
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0016 0.0049 0.0049
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0116 0.1152 0.1554
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0013 0.0016 0.0194
Giardia lamblia PHD finger protein 15 0.0028 0.0188 0.0488
Brugia malayi Bromodomain containing protein 0.0037 0.0285 0.0385
Plasmodium falciparum tubulin epsilon chain, putative 0.0088 0.0843 1
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.042 0.1308
Schistosoma mansoni neuroligin 3 (S09 family) 0.0116 0.1152 0.1554
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0174 0.2064
Schistosoma mansoni BC026374 protein (S09 family) 0.0116 0.1152 0.1554
Schistosoma mansoni tyrosine kinase 0.0039 0.0303 0.0408
Echinococcus multilocularis tubulin alpha chain 0.0088 0.0843 0.0843
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0328 0.2005
Onchocerca volvulus 0.0116 0.1152 0.4802
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0309 0.0417
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0013 0.0016 0.0022
Echinococcus multilocularis tubulin alpha chain 0.0088 0.0843 0.0843
Brugia malayi Cathepsin L-like precursor 0.0013 0.0016 0.0022
Echinococcus multilocularis tubulin delta chain 0.0038 0.0298 0.0298
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0182 0.2007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Plasmodium falciparum alpha tubulin 2 0.0088 0.0843 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0016 0.0051
Trypanosoma brucei ISWI complex protein 0.0015 0.0041 0.01
Schistosoma mansoni hypothetical protein 0.0028 0.0188 0.0254
Loa Loa (eye worm) hypothetical protein 0.0088 0.0843 0.1137
Leishmania major alpha tubulin 0.0088 0.0843 1
Trichomonas vaginalis tubulin, putative 0.0038 0.0298 0.0928
Echinococcus multilocularis Tubulin beta 2C chain 0.0088 0.0843 0.0843
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0423 0.0571
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0069 0.0215
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0328 0.0328
Loa Loa (eye worm) hypothetical protein 0.0688 0.7412 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0443
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0016 0.0049 0.0066
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0148 0.1506 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0493 0.5848
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0016 0.0051
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0066 0.009
Brugia malayi Latrophilin receptor protein 2 0.005 0.0423 0.0571
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0016 0.0049 0.0066
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0148 0.1506 1
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.042 0.1308
Brugia malayi beta-tubulin, identical 0.0088 0.0843 0.1137
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.4218 0.4218
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0284 0.0284
Brugia malayi Bromodomain containing protein 0.0031 0.0213 0.0288
Loa Loa (eye worm) hypothetical protein 0.0116 0.1152 0.1554
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0328 0.1023
Echinococcus multilocularis Tubulin beta 2C chain 0.0088 0.0843 0.0843
Schistosoma mansoni nuclear hormone receptor 0.0016 0.0049 0.0066
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0049 0.0066
Schistosoma mansoni hypothetical protein 0.005 0.0423 0.0571
Schistosoma mansoni retinoic acid receptor RXR 0.0016 0.0049 0.0066
Giardia lamblia Alpha-tubulin 0.0088 0.0843 0.255
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0016 0.0049 0.0066
Brugia malayi CXXC zinc finger family protein 0.0028 0.0184 0.0248
Loa Loa (eye worm) beta-lactamase 0.0041 0.0328 0.0443
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0293 0.0914
Brugia malayi Tubulin beta chain 0.005 0.0425 0.0573
Onchocerca volvulus 0.0039 0.0303 0.1262
Leishmania major beta tubulin 0.0088 0.0843 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0016 0.0049 0.0066
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0049 0.0066
Leishmania major hypothetical protein, conserved 0.0041 0.0328 0.3774
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0098 0.0132
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0182 0.0568
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0016 0.0049 0.0066
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0579 0.681
Brugia malayi CHD4 protein 0.0014 0.0038 0.0051
Brugia malayi hypothetical protein 0.0027 0.0174 0.0235
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0423 0.0571
Brugia malayi beta-lactamase family protein 0.0041 0.0328 0.0443
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0328 0.0443
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0016 0.0049 0.0066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0016 0.0051
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0455 0.0455
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0468 0.5002 0.6748
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0579 0.0782
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0298 0.0928
Onchocerca volvulus Huntingtin homolog 0.014 0.1408 0.587
Schistosoma mansoni metabotropic glutamate receptor 0.02 0.2075 0.2799
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.045 0.0607
Echinococcus granulosus calpain A 0.0148 0.1496 0.2018
Brugia malayi photoreceptor-specific nuclear receptor 0.0016 0.0049 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0016 0.0049 0.0066
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0328 0.1086
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0038 0.0298 0.0928
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0688 0.7412 1
Echinococcus multilocularis tubulin alpha chain 0.0088 0.0843 0.0843
Schistosoma mansoni gliotactin 0.0116 0.1152 0.1554
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0016 0.0051
Schistosoma mansoni calpain C (C02 family) 0.0042 0.0337 0.0454
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0455 0.0614
Loa Loa (eye worm) hypothetical protein 0.0046 0.0385 0.052
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0328 0.1023
Trypanosoma brucei alpha tubulin, putative 0.005 0.0425 0.4831
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0328 0.3774
Schistosoma mansoni protein kinase 0.0039 0.0303 0.0408
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0049 0.042 0.4877
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0049 0.042 0.4877
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0184 0.0248
Leishmania major gamma-tubulin 0.0088 0.0843 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.053 0.053
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0042 0.0337 0.3874
Echinococcus multilocularis GPCR, family 3, C terminal 0.0067 0.061 0.061
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0304 0.3209 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0028 0.0182 0.0246
Onchocerca volvulus 0.0041 0.0328 0.1369
Loa Loa (eye worm) hypothetical protein 0.0116 0.1152 0.1554
Schistosoma mansoni ap endonuclease 0.0014 0.0033 0.0045
Schistosoma mansoni hypothetical protein 0.0067 0.061 0.0823
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0069 0.0215
Trichomonas vaginalis tubulin beta chain, putative 0.005 0.0425 0.1323
Onchocerca volvulus Protein ultraspiracle homolog 0.0016 0.0049 0.0205
Trypanosoma brucei alpha tubulin 0.0088 0.0843 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0349 0.0471
Loa Loa (eye worm) hypothetical protein 0.0039 0.0303 0.0408
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0042 0.0337 0.3874
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0016 0.0049 0.0049
Entamoeba histolytica tubulin alpha chain, putative 0.0088 0.0843 0.2628
Brugia malayi Papain family cysteine protease containing protein 0.0013 0.0016 0.0022
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0309 0.0309
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0284 0.2986 0.4029
Loa Loa (eye worm) tubulin beta-1 chain 0.0088 0.0843 0.1137
Giardia lamblia Beta tubulin 0.0088 0.0843 0.255
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.045 0.0607
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0069 0.0215
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0385 0.052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0088 0.0843 0.0843
Onchocerca volvulus 0.0041 0.0323 0.1348
Trypanosoma cruzi tubulin delta chain 0.0038 0.0298 0.3402
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0016 0.0049 0.0066
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.1598 0.2156
Mycobacterium tuberculosis Conserved protein 0.0041 0.0328 0.1086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Trypanosoma brucei calpain-like protein, putative 0.0042 0.0337 0.3746
Loa Loa (eye worm) BEN-1 protein 0.0088 0.0843 0.1137
Loa Loa (eye worm) hypothetical protein 0.0116 0.1152 0.1554
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0174 0.1738
Echinococcus granulosus Tubulin alpha 1 chain 0.0088 0.0843 0.1137
Leishmania major alpha tubulin 0.0088 0.0843 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0579 0.681
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0188 0.0254
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0385 0.052
Echinococcus granulosus cathepsin L cysteine proteinase 0.0013 0.0016 0.0022
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0618 0.1927
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0148 0.1506 0.5419
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0328 0.1023
Echinococcus granulosus neuroligin 0.0116 0.1152 0.1554
Echinococcus multilocularis calpain 5 0.0042 0.0337 0.0337
Echinococcus granulosus FTZ F1 alpha 0.0016 0.0049 0.0066
Echinococcus granulosus calpain 0.0042 0.0337 0.0454
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0291 0.0393
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0116 0.1152 0.359
Onchocerca volvulus 0.0013 0.0016 0.0068
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0039 0.0303 0.0408
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0049 0.042 0.4977
Schistosoma mansoni tubulin subunit beta 0.0088 0.0843 0.1137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0013 0.0016 0.0016
Trichomonas vaginalis tubulin epsilon chain, putative 0.0088 0.0843 0.2628
Onchocerca volvulus 0.0039 0.0303 0.1262
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0148 0.1496 0.2018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Loa Loa (eye worm) tubulin alpha 2 0.005 0.0425 0.0573
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0323 0.0436
Brugia malayi follicle stimulating hormone receptor 0.0241 0.2514 0.3392
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0038 0.0298 0.353
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0016 0.0051
Loa Loa (eye worm) hypothetical protein 0.0506 0.5425 0.732
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0184 0.0248
Echinococcus granulosus tubulin alpha chain 0.0088 0.0843 0.1137
Brugia malayi PHD-finger family protein 0.0013 0.0018 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0182 0.0568
Trypanosoma cruzi cysteine peptidase, putative 0.0048 0.0402 0.4667
Loa Loa (eye worm) tubulin alpha-3 chain 0.0038 0.0298 0.0402
Echinococcus granulosus tubulin beta 1 chain 0.0088 0.0843 0.1137
Brugia malayi Metabotropic glutamate receptor precursor. 0.0411 0.4384 0.5915
Toxoplasma gondii ABC1 family protein 0.0041 0.0328 0.3895
Loa Loa (eye worm) acetylcholinesterase 1 0.0688 0.7412 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0088 0.0843 0.0843
Echinococcus multilocularis chromobox protein 1 0.0067 0.0618 0.0618
Trypanosoma cruzi cruzipain precursor, putative 0.0048 0.0402 0.4667
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0038 0.0051
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0328 0.0443
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0579 0.0579
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0325 0.1012
Trichomonas vaginalis tubulin beta chain, putative 0.0088 0.0843 0.2628
Onchocerca volvulus 0.0028 0.0184 0.0766
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0013 0.0016 0.0022
Plasmodium falciparum tubulin gamma chain 0.0088 0.0843 1
Mycobacterium leprae Probable lipase LipE 0.0041 0.0328 0.0255
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0579 0.6743
Brugia malayi Pre-SET motif family protein 0.003 0.0202 0.0273
Leishmania major hypothetical protein, conserved 0.0027 0.0174 0.1907
Plasmodium falciparum tubulin beta chain 0.0088 0.0843 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0172 0.0537
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0423 0.0423
Onchocerca volvulus 0.0116 0.1152 0.4802
Trypanosoma cruzi tubulin delta chain 0.0038 0.0298 0.3402
Trichomonas vaginalis tubulin beta chain, putative 0.0088 0.0843 0.2628
Loa Loa (eye worm) tubulin beta chain 0.0038 0.0298 0.0402
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0016 0.0049 0.0066
Schistosoma mansoni ap endonuclease 0.0014 0.0033 0.0045
Echinococcus multilocularis peroxisome assembly protein 26 0.0088 0.0843 0.0843
Leishmania major beta tubulin 0.0088 0.0843 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0016 0.0049 0.0066
Echinococcus granulosus tubulin delta chain 0.0038 0.0298 0.0402
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0049 0.042 0.4877
Loa Loa (eye worm) cysteine protease 0.0013 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.0068 0.0629 0.0849
Trichomonas vaginalis tubulin gamma chain, putative 0.0038 0.0298 0.0928
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0042 0.0337 0.3874
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0116 0.1152 0.4117
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0066
Giardia lamblia Kinase, CMGC MAPK 0.0049 0.042 0.1217
Trichomonas vaginalis tubulin, putative 0.0088 0.0843 0.2628
Schistosoma mansoni hypothetical protein 0.002 0.0098 0.0132
Loa Loa (eye worm) calpain 5 0.0042 0.0337 0.0454
Trichomonas vaginalis tubulin epsilon chain, putative 0.0088 0.0843 0.2628
Echinococcus granulosus Tubulin beta 2C chain 0.0088 0.0843 0.1137
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0262 0.275 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0455 0.0455
Treponema pallidum fructose-bisphosphate aldolase 0.0304 0.3209 1
Brugia malayi Tubulin alpha chain 0.0038 0.0298 0.0402
Echinococcus granulosus tubulin alpha chain 0.0088 0.0843 0.1137
Schistosoma mansoni calpain-7 (C02 family) 0.0044 0.0361 0.0487
Brugia malayi chromobox protein homolog 3 0.0038 0.0293 0.0396
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0423 0.0423
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0088 0.0843 0.2628
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0016 0.0049 0.0066
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0385 0.052
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0188 0.0254
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0385 0.1605
Plasmodium vivax tubulin alpha chain, putative 0.0088 0.0843 1
Echinococcus granulosus tubulin beta 4A class IVa 0.0088 0.0843 0.1137
Echinococcus granulosus Tubulin beta 2C chain 0.0088 0.0843 0.1137
Onchocerca volvulus 0.0013 0.0016 0.0068
Trypanosoma brucei antigen, putative 0.0042 0.0337 0.3746
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0182 0.0568
Mycobacterium ulcerans cell division protein FtsZ 0.0038 0.0298 0.1796
Brugia malayi Tubulin beta chain 0.0038 0.0298 0.0402
Brugia malayi jmjC domain containing protein 0.0038 0.0291 0.0393
Onchocerca volvulus 0.0013 0.0016 0.0068
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0443
Trichomonas vaginalis tubulin, putative 0.005 0.0425 0.1323
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0174 0.2064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.3209 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0028 0.0182 0.0246
Trypanosoma brucei beta tubulin 0.0088 0.0843 1
Onchocerca volvulus 0.0046 0.0385 0.1605
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0202 0.0202
Brugia malayi N-terminal motif family protein 0.0193 0.1992 0.2687
Brugia malayi SET domain containing protein 0.0013 0.0018 0.0025
Echinococcus granulosus atrial natriuretic peptide receptor 0.0039 0.0303 0.0408
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0188 0.0254
Echinococcus multilocularis acetylcholinesterase 0.0688 0.7412 0.7412
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0328 0.0443
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.045 0.0607
Schistosoma mansoni Mername-AA248 (C02 family) 0.0042 0.0337 0.0454
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0039 0.0303 0.0303
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.1598 0.2156
Trypanosoma brucei protein kinase, putative 0.0049 0.042 0.477
Plasmodium vivax vivapain-2 0.0013 0.0016 0.0194
Onchocerca volvulus 0.003 0.0204 0.085
Loa Loa (eye worm) hypothetical protein 0.0688 0.7412 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.0182 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0172 0.0537
Trichomonas vaginalis tubulin epsilon chain, putative 0.0088 0.0843 0.2628
Echinococcus multilocularis GPCR, family 2 0.005 0.0423 0.0423
Leishmania major kinesin, putative 0.0042 0.0337 0.3874
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0185 0.1904 0.1904
Loa Loa (eye worm) hypothetical protein 0.0039 0.0303 0.0408
Schistosoma mansoni cpg binding protein 0.0028 0.0184 0.0248
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0579 0.0782
Echinococcus granulosus GPCR family 3 C terminal 0.0067 0.061 0.0823
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0039 0.0303 0.0408
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0033 0.0395
Onchocerca volvulus Cathepsin L homolog 0.0013 0.0016 0.0068
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0028 0.0182 0.2007
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0443
Onchocerca volvulus 0.0041 0.0328 0.1369
Plasmodium vivax tubulin gamma chain, putative 0.0088 0.0843 1
Leishmania major beta tubulin 0.0088 0.0843 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0579 0.1806
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0284 0.0384
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0443
Loa Loa (eye worm) ctsf protein 0.0013 0.0016 0.0022
Trichomonas vaginalis tubulin, putative 0.005 0.0425 0.1323
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Echinococcus granulosus alpha tubulin 0.0088 0.0843 0.1137
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0328 0.1086
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0042 0.0337 0.3874
Onchocerca volvulus 0.0013 0.0016 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0037 0.0115
Echinococcus granulosus beta tubulin 0.0088 0.0843 0.1137
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0016 0.0049 0.0066
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0052 0.045 0.0607
Giardia lamblia Beta tubulin 0.0088 0.0843 0.255
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0136 0.0183
Echinococcus multilocularis receptor type guanylyl cyclase 0.0039 0.0303 0.0303
Loa Loa (eye worm) beta-tubulin 0.0088 0.0843 0.1137
Loa Loa (eye worm) hypothetical protein 0.0037 0.0286 0.0386
Brugia malayi Steroid receptor seven-up type 2 0.0016 0.0049 0.0066
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0038 0.0298 1
Echinococcus granulosus glutamate receptor 2 0.0039 0.0303 0.0408
Echinococcus granulosus cathepsin l cysteine peptidase 0.0013 0.0016 0.0022
Onchocerca volvulus Poor gastrulation protein homolog 0.0067 0.061 0.2544
Mycobacterium tuberculosis Conserved protein 0.0041 0.0328 0.1086
Schistosoma mansoni hypothetical protein 0.0176 0.1809 0.2441
Brugia malayi calpain 5 0.0042 0.0337 0.0454
Schistosoma mansoni calpain (C02 family) 0.0042 0.0337 0.0454
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0044 0.0357 0.4118
Echinococcus granulosus dnaJ subfamily B 0.0396 0.4218 0.5691
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0033 0.0104
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0042 0.0337 0.3874
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0328 0.0443
Loa Loa (eye worm) hypothetical protein 0.005 0.0423 0.0571
Echinococcus multilocularis Chromobox protein 3 0.0011 0.000000013265 0.000000013265
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0069 0.0215
Trichomonas vaginalis tubulin beta chain, putative 0.0088 0.0843 0.2628
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0328 0.1023
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0016 0.0049 0.0049
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0455 0.0614
Loa Loa (eye worm) glutamate receptor 0.0411 0.4384 0.5915
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0202 0.24
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0303 0.0408
Brugia malayi Carboxylesterase family protein 0.0116 0.1152 0.1554
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0383 0.0383
Onchocerca volvulus 0.0099 0.0959 0.3999
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0066
Trypanosoma brucei calpain-like protein, putative 0.0042 0.0337 0.3746
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0066
Onchocerca volvulus 0.0013 0.0016 0.0068
Echinococcus multilocularis hypothetical protein 0.0088 0.0843 0.0843
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0188 0.2234
Trypanosoma cruzi tubulin gamma chain 0.0088 0.0843 1
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0049 0.0066
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0328 0.1086
Loa Loa (eye worm) hypothetical protein 0.0028 0.0188 0.0254
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0182 0.184
Trypanosoma brucei calpain-like protein, putative 0.0042 0.0337 0.3746
Loa Loa (eye worm) hypothetical protein 0.0041 0.0328 0.0443
Loa Loa (eye worm) hypothetical protein 0.0099 0.0959 0.1294
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0383 0.0517
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0039 0.0303 0.0408
Schistosoma mansoni hypothetical protein 0.005 0.0423 0.0571
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.005 0.0425 0.1323
Echinococcus granulosus receptor type guanylyl cyclase 0.0039 0.0303 0.0408
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0293 0.0914
Schistosoma mansoni hypothetical protein 0.0396 0.4218 0.5691
Loa Loa (eye worm) tubulin alpha-2 chain 0.0088 0.0843 0.1137
Echinococcus multilocularis hypothetical protein 0.0042 0.0337 0.0337
Toxoplasma gondii exonuclease III APE 0.0014 0.0033 0.0395
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0202 0.0273
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0325 0.1012
Brugia malayi alpha-tubulin 0.0088 0.0843 0.1137
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0148 0.1496 0.2018
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0105 0.0142
Trypanosoma cruzi major cysteine proteinase, putative 0.0038 0.029 0.3313
Onchocerca volvulus Alhambra homolog 0.0028 0.0188 0.0785
Leishmania major cathepsin L-like protease 0.0048 0.0402 0.4667
Schistosoma mansoni coup transcription factor 0.0016 0.0049 0.0066
Giardia lamblia Alpha-tubulin 0.0088 0.0843 0.255
Leishmania major cathepsin L-like protease 0.0048 0.0402 0.4667
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.0049 0.0066
Echinococcus granulosus tubulin subunit beta 0.0088 0.0843 0.1137
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0042 0.0337 0.3874
Leishmania major beta tubulin 0.0088 0.0843 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.006 0.0081
Loa Loa (eye worm) calpain 0.0042 0.0337 0.0454
Leishmania major beta tubulin 0.0088 0.0843 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0385 0.0385
Echinococcus multilocularis tubulin epsilon chain 0.0088 0.0843 0.0843
Loa Loa (eye worm) hypothetical protein 0.003 0.0204 0.0275
Loa Loa (eye worm) hypothetical protein 0.0046 0.0383 0.0517
Brugia malayi Cathepsin L-like precursor 0.0013 0.0016 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Schistosoma mansoni alpha tubulin 0.0088 0.0843 0.1137
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0188 0.2234
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0148 0.1496 0.1496
Loa Loa (eye worm) MBCTL1 0.0053 0.0455 0.0614
Loa Loa (eye worm) hypothetical protein 0.0099 0.0959 0.1294
Echinococcus multilocularis Tubulin alpha 1 chain 0.0088 0.0843 0.0843
Loa Loa (eye worm) fibroinase 0.0013 0.0016 0.0022
Echinococcus granulosus beta tubulin 0.0088 0.0843 0.1137
Echinococcus granulosus Tubulin beta 2C chain 0.0088 0.0843 0.1137
Leishmania major alpha tubulin 0.0088 0.0843 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.061 0.0823
Echinococcus granulosus zinc finger protein 0.0021 0.0104 0.014
Leishmania major alpha tubulin 0.0088 0.0843 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0013 0.0016 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.3209 1
Brugia malayi Receptor family ligand binding region containing protein 0.0105 0.1034 0.1395
Loa Loa (eye worm) hypothetical protein 0.0039 0.0303 0.0408
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0116 0.1152 0.1554
Trypanosoma cruzi zeta tubulin, putative 0.0038 0.0298 0.3402
Giardia lamblia Fructose-bisphosphate aldolase 0.0304 0.3209 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.1054 0.1422
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.3209 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.1152 0.1554
Echinococcus granulosus tubulin alpha chain 0.0088 0.0843 0.1137
Loa Loa (eye worm) hypothetical protein 0.014 0.1417 0.1912
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0067 0.061 0.0823
Trypanosoma cruzi epsilon tubulin, putative 0.0088 0.0843 1
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0067 0.061 0.2544
Toxoplasma gondii beta-tubulin, putative 0.0088 0.0843 1
Trichomonas vaginalis tubulin beta chain, putative 0.0088 0.0843 0.2628
Loa Loa (eye worm) hypothetical protein 0.0027 0.0174 0.0235
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0013 0.0016 0.0051
Onchocerca volvulus 0.0013 0.0016 0.0068
Loa Loa (eye worm) carboxylesterase 0.0116 0.1152 0.1554
Onchocerca volvulus 0.0116 0.1152 0.4802
Brugia malayi hypothetical protein 0.0017 0.0069 0.0094
Leishmania major beta tubulin 0.0088 0.0843 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0385 0.052
Brugia malayi Cathepsin L-like precursor 0.0013 0.0016 0.0022
Entamoeba histolytica hypothetical protein 0.0039 0.0303 0.0943
Echinococcus granulosus mitogen activated protein kinase 0.0049 0.042 0.0566
Trypanosoma brucei beta tubulin 0.0088 0.0843 1
Leishmania major alpha tubulin 0.0088 0.0843 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0303 0.0408
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0425 0.1323
Leishmania major beta tubulin 0.0088 0.0843 1
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0033 0.0104
Brugia malayi nuclear receptor NHR-88 0.0016 0.0049 0.0066
Entamoeba histolytica tubulin family protein 0.0088 0.0843 0.2628
Echinococcus granulosus tubulin alpha 3 chain 0.0088 0.0843 0.1137
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0136 0.0183
Echinococcus multilocularis Tubulin beta 2C chain 0.0088 0.0843 0.0843
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0022
Entamoeba histolytica tubulin gamma chain 0.0088 0.0843 0.2628
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0016 0.0051
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0049 0.042 0.4877
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0069 0.0215
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.005 0.0425 0.1323
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0028 0.0182 0.0246
Loa Loa (eye worm) tubulin beta chain 0.0088 0.0843 0.1137
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.3209 1
Echinococcus multilocularis nmda type glutamate receptor 0.0039 0.0303 0.0303
Brugia malayi Guanylyl cyclase protein 23 0.0039 0.0303 0.0408
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0328 0.1023
Echinococcus granulosus ecdysone induced protein 78C 0.0016 0.0049 0.0066
Entamoeba histolytica calpain large subunit domain III containing protein 0.0042 0.0337 0.1049
Trypanosoma brucei calpain-like protein, putative 0.0042 0.0337 0.3746
Schistosoma mansoni hypothetical protein 0.0176 0.1809 0.2441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Echinococcus granulosus mitogen activated protein kinase 3 0.0049 0.042 0.0566
Brugia malayi MAP kinase sur-1 0.0049 0.042 0.0566
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0016 0.0051
Brugia malayi exodeoxyribonuclease III family protein 0.0014 0.0033 0.0045
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0253 0.0253
Schistosoma mansoni hypothetical protein 0.0012 0.0011 0.0015
Trichomonas vaginalis tubulin gamma chain, putative 0.0088 0.0843 0.2628
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0049 0.042 0.477
Plasmodium vivax vivapain-2 0.0013 0.0016 0.0194
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.0033 0.0205
Schistosoma mansoni bromodomain containing protein 0.0063 0.0568 0.0766
Loa Loa (eye worm) RGC/RGC protein kinase 0.0039 0.0303 0.0408
Brugia malayi Cathepsin L-like precursor 0.0013 0.0016 0.0022
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0325 0.1354
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.045 0.0607
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0066
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0088 0.0843 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0293 0.1223
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0016 0.0049 0.0066
Leishmania major alpha tubulin 0.0088 0.0843 1
Brugia malayi Carboxylesterase family protein 0.0116 0.1152 0.1554
Trypanosoma brucei epsilon tubulin 0.0088 0.0843 1
Loa Loa (eye worm) BEN-1 protein 0.0088 0.0843 0.1137
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.042 0.1308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0069 0.0215
Brugia malayi steroid hormone receptor 0.0016 0.0049 0.0066
Echinococcus granulosus Chromobox protein 3 0.0011 0.000000013265 0.000000017897
Echinococcus granulosus tubulin alpha 1C chain 0.0088 0.0843 0.1137
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0298 0.0928
Echinococcus granulosus BC026374 protein S09 family 0.0116 0.1152 0.1554
Brugia malayi Carboxylesterase family protein 0.0688 0.7412 1
Trichomonas vaginalis esterase, putative 0.0041 0.0328 0.1023
Echinococcus granulosus chromobox protein 1 0.0067 0.0618 0.0834
Schistosoma mansoni alpha tubulin 0.0088 0.0843 0.1137
Schistosoma mansoni tubulin subunit beta 0.0088 0.0843 0.1137
Schistosoma mansoni jumonji domain containing protein 0.0073 0.0684 0.0923
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0042 0.0337 0.3874
Leishmania major beta tubulin 0.0088 0.0843 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.0049 0.0049
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0383 0.0517
Leishmania major alpha tubulin 0.0088 0.0843 1
Trypanosoma cruzi ISWI complex protein 0.0015 0.0041 0.0302
Trypanosoma brucei tubulin gamma chain 0.0088 0.0843 1
Schistosoma mansoni tubulin subunit beta 0.0038 0.0298 0.0402
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Brugia malayi Pre-SET motif family protein 0.0202 0.2094 0.2825
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0066
Echinococcus multilocularis neuroligin 0.0116 0.1152 0.1152
Loa Loa (eye worm) hypothetical protein 0.014 0.1408 0.19
Entamoeba histolytica tubulin family protein 0.0088 0.0843 0.2628
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0016 0.0049 0.0066
Trichomonas vaginalis set domain proteins, putative 0.023 0.2399 0.7476
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.053 0.0715
Trichomonas vaginalis tubulin alpha chain, putative 0.0088 0.0843 0.2628
Plasmodium falciparum cysteine proteinase falcipain 3 0.0013 0.0016 0.0194
Giardia lamblia Beta tubulin 0.0088 0.0843 0.255
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0014 0.0033 0.0205
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0385 0.052
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0304 0.3209 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.026 0.0351
Trichomonas vaginalis tubulin epsilon chain, putative 0.0038 0.0298 0.0928
Leishmania major beta tubulin 0.0088 0.0843 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0038 0.0051
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0136 0.0136
Echinococcus multilocularis glutamate receptor 2 0.0039 0.0303 0.0303
Leishmania major beta tubulin 0.0088 0.0843 1
Leishmania major cathepsin L-like protease 0.0048 0.0402 0.4667
Entamoeba histolytica protein kinase, putative 0.0042 0.0342 0.1064
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0328 0.1086
Schistosoma mansoni glutamate receptor NMDA 0.0039 0.0303 0.0408
Brugia malayi Tubulin alpha-2 chain 0.0088 0.0843 0.1137
Schistosoma mansoni acetylcholinesterase 0.0116 0.1152 0.1554
Loa Loa (eye worm) carboxylesterase 0.0688 0.7412 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.0892 0.0892
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0049 0.042 0.0566
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0291 0.0393
Trichomonas vaginalis tubulin alpha chain, putative 0.0088 0.0843 0.2628
Leishmania major beta tubulin 0.0088 0.0843 1
Schistosoma mansoni tubulin subunit alpha 0.0088 0.0843 0.1137
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0618 0.1927
Echinococcus multilocularis tubulin alpha 3 chain 0.0088 0.0843 0.0843
Brugia malayi ecdysteroid receptor 0.0016 0.0049 0.0066
Trypanosoma cruzi ISWI complex protein 0.0015 0.0041 0.0302
Echinococcus multilocularis chromobox protein 1 0.0067 0.0618 0.0618
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0052 0.045 0.0607
Echinococcus granulosus tubulin epsilon chain 0.0088 0.0843 0.1137
Echinococcus granulosus metabotropic glutamate receptor 2 0.0344 0.3653 0.4929
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0042 0.0337 0.3746
Schistosoma mansoni zinc finger protein 0.0021 0.0104 0.014
Echinococcus granulosus peroxisome assembly protein 26 0.0088 0.0843 0.1137
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0014 0.0033 0.0045
Echinococcus multilocularis zinc finger protein 0.0021 0.0104 0.0104
Leishmania major beta tubulin 0.0088 0.0843 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0013 0.0016 0.0051
Schistosoma mansoni hypothetical protein 0.005 0.0423 0.0571
Echinococcus multilocularis tubulin alpha 1C chain 0.0088 0.0843 0.0843
Schistosoma mansoni cpg binding protein 0.0031 0.0221 0.0299
Mycobacterium ulcerans hypothetical protein 0.0041 0.0328 0.2005
Echinococcus multilocularis calpain 0.0042 0.0337 0.0337
Echinococcus granulosus tubulin alpha 3 chain 0.0088 0.0843 0.1137
Echinococcus multilocularis Tubulin beta 2C chain 0.0088 0.0843 0.0843
Entamoeba histolytica cysteine protease, putative 0.0013 0.0016 0.0051
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0038 0.0038
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0016 0.0049 0.0066
Loa Loa (eye worm) glutamate receptor 0.0162 0.1651 0.2228
Echinococcus granulosus tubulin alpha 0.0088 0.0843 0.1137
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0066
Onchocerca volvulus Cathepsin F homolog 0.0013 0.0016 0.0068
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0016 0.0049 0.0066
Echinococcus multilocularis tyrosine kinase 0.0039 0.0303 0.0303
Brugia malayi mbt repeat family protein 0.0046 0.0385 0.052
Loa Loa (eye worm) hypothetical protein 0.0053 0.0455 0.0614
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0016 0.0051
Schistosoma mansoni hypothetical protein 0.0107 0.1054 0.1422
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0016 0.0049 0.0066
Echinococcus granulosus tubulin gamma 1 chain 0.0088 0.0843 0.1137
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0016 0.0049 0.0066
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0016 0.0049 0.0205
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0069 0.0215
Brugia malayi metabotropic glutamate receptor type 2 0.02 0.2075 0.2799
Echinococcus granulosus Tubulin beta 2C chain 0.0088 0.0843 0.1137
Echinococcus granulosus tyrosine kinase 0.0039 0.0303 0.0408
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.042 0.0566
Brugia malayi Carboxylesterase family protein 0.0116 0.1152 0.1554
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0013 0.0016 0.0051
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0328 0.1086
Brugia malayi Tubulin alpha chain 0.0088 0.0843 0.1137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0016 0.0049 0.0066
Trypanosoma brucei alpha tubulin 0.0088 0.0843 1
Schistosoma mansoni tubulin subunit beta 0.0088 0.0843 0.1137
Leishmania major extracellular receptor, putative 0.0039 0.0303 0.3463
Plasmodium falciparum phd finger protein, putative 0.0028 0.0188 0.2234
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0188 0.2234
Loa Loa (eye worm) hypothetical protein 0.0039 0.0303 0.0408
Echinococcus multilocularis ubiquitin specific protease 41 0.0028 0.0182 0.0182
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0039 0.0303 0.0303
Brugia malayi jmjC domain containing protein 0.0092 0.0892 0.1203
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0048 0.0402 0.4556
Echinococcus multilocularis calpain family protein 1, d 0.0099 0.0959 0.0959
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0039 0.0303 0.0408
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Loa Loa (eye worm) hypothetical protein 0.0016 0.0049 0.0066
Brugia malayi hypothetical protein 0.0039 0.0303 0.0408
Leishmania major beta tubulin 0.0088 0.0843 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0016 0.0049 0.0049
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0579 0.681
Echinococcus granulosus tubulin alpha chain 0.0088 0.0843 0.1137
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.045 0.045
Treponema pallidum cell division protein FtsZ 0.0038 0.0298 0.0833
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0014 0.0033 0.0104
Brugia malayi Heterochromatin protein 1 0.0067 0.0618 0.0834
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0037 0.0115
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0038 0.0051
Leishmania major beta tubulin 0.0088 0.0843 1
Brugia malayi Carboxylesterase family protein 0.0116 0.1152 0.1554
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0014 0.0033 0.0033
Echinococcus granulosus Tubulin beta 2C chain 0.0088 0.0843 0.1137
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0028 0.0182 0.0182
Trypanosoma cruzi alpha tubulin, putative 0.0088 0.0843 1
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0038 0.0298 0.353
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0028 0.0182 0.0469
Echinococcus granulosus ubiquitin specific protease 41 0.0028 0.0182 0.0246
Echinococcus granulosus geminin 0.0176 0.1809 0.2441
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0537 0.0724
Brugia malayi Tubulin alpha-2 chain 0.0088 0.0843 0.1137
Giardia lamblia Epsilon tubulin 0.0038 0.0298 0.0833
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0174 0.1907
Onchocerca volvulus 0.0041 0.0328 0.1369
Echinococcus granulosus cpg binding protein 0.0031 0.0221 0.0299
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0039 0.0303 0.0303
Brugia malayi beta-lactamase family protein 0.0041 0.0328 0.0443
Trypanosoma brucei beta tubulin 0.0088 0.0843 1
Mycobacterium ulcerans beta-lactamase 0.0041 0.0328 0.2005
Leishmania major alpha tubulin 0.0088 0.0843 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0311 0.042
Leishmania major beta tubulin 0.0088 0.0843 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.1598 0.2156
Onchocerca volvulus Cathepsin L homolog 0.0013 0.0016 0.0068
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0028 0.0182 0.0246
Loa Loa (eye worm) hypothetical protein 0.0039 0.0303 0.0408
Echinococcus multilocularis calpain 7 (C02 family) 0.0042 0.0337 0.0337
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0013 0.0016 0.0194
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0105 0.1034 0.1395
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0016 0.0049 0.0066
Echinococcus granulosus acetylcholinesterase 0.0688 0.7412 1
Schistosoma mansoni alpha tubulin 0.0088 0.0843 0.1137
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0039 0.0303 0.0303
Loa Loa (eye worm) tubulin beta-4 chain 0.0088 0.0843 0.1137
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0241 0.2514 0.3392
Plasmodium vivax calpain, putative 0.0042 0.0337 0.3993
Toxoplasma gondii alpha-tubulin I, putative 0.0088 0.0843 1
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0328 0.1086
Schistosoma mansoni zinc finger protein 0.0015 0.0041 0.0056
Loa Loa (eye worm) tubulin alpha 2 0.005 0.0425 0.0573
Echinococcus multilocularis Tubulin beta 2C chain 0.0088 0.0843 0.0843
Brugia malayi Cell division protein ftsZ 0.0038 0.0298 0.0402
Loa Loa (eye worm) tubulin gamma chain 0.0088 0.0843 0.1137
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0016 0.0049 0.0049
Brugia malayi nuclear hormone receptor 0.0016 0.0049 0.0066
Loa Loa (eye worm) tubulin alpha chain 0.0088 0.0843 0.1137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0016 0.0051
Loa Loa (eye worm) hypothetical protein 0.0039 0.0303 0.0408
Loa Loa (eye worm) steroid hormone receptor 0.0016 0.0049 0.0066
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0016 0.0049 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.3209 1
Schistosoma mansoni chromobox protein 0.0067 0.0618 0.0834
Brugia malayi mbt repeat family protein 0.0046 0.0385 0.052
Plasmodium vivax tubulin alpha chain, putative 0.0088 0.0843 1
Plasmodium falciparum alpha tubulin 1 0.0088 0.0843 1
Trypanosoma brucei epsilon tubulin 0.0088 0.0843 1
Plasmodium falciparum tubulin delta chain, putative 0.0038 0.0298 0.353
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0579 0.0782
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0328 0.3895
Brugia malayi Cathepsin L-like precursor 0.0013 0.0016 0.0022
Echinococcus multilocularis tubulin alpha chain 0.0088 0.0843 0.0843
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0328 0.1086
Echinococcus multilocularis geminin 0.0176 0.1809 0.1809
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.026 0.026
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0014 0.0033 0.0045
Schistosoma mansoni metabotropic glutamate receptor 0.0344 0.3653 0.4929
Loa Loa (eye worm) alpha-tubulin 0.0088 0.0843 0.1137
Echinococcus multilocularis mitogen activated protein kinase 0.0049 0.042 0.042
Onchocerca volvulus 0.0116 0.1152 0.4802
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0579 0.0782
Mycobacterium tuberculosis Conserved protein 0.0041 0.0328 0.1086

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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