Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0036 | 0.6941 | 1 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0036 | 0.6941 | 0.6941 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0036 | 0.6941 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0 | 0.5 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0036 | 0.6941 | 1 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.6941 | 0.6941 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0036 | 0.6941 | 0.6941 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0044 | 1 | 1 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0036 | 0.6941 | 0.6941 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 1 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0044 | 1 | 1 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0036 | 0.6941 | 0.6941 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0044 | 1 | 1 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0036 | 0.6941 | 0.6941 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | DNA polymerase eta | 0.0044 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0031 | 0.4775 | 0.4775 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.6941 | 0.6941 |
Echinococcus multilocularis | dna polymerase eta | 0.0044 | 1 | 1 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.6941 | 0.6941 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.6941 | 0.6941 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.6941 | 0.6941 |
Leishmania major | DNA polymerase eta, putative | 0.0044 | 1 | 1 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0036 | 0.6941 | 0.6941 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0031 | 0.4775 | 0.5 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0036 | 0.6941 | 1 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0036 | 0.6941 | 0.6941 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.6941 | 1 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0036 | 0.6941 | 0.6941 |
Leishmania major | DNA polymerase eta, putative | 0.0031 | 0.4775 | 0.4775 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0036 | 0.6941 | 0.6941 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.