Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0055 | 0.0121 | 0.0289 |
Brugia malayi | AMP-binding enzyme family protein | 0.0335 | 0.1216 | 0.2973 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0108 | 0.0328 | 0.0674 |
Plasmodium falciparum | acyl carrier protein | 0.0036 | 0.0047 | 0.0548 |
Onchocerca volvulus | 0.0335 | 0.1216 | 0.2622 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.014 | 0.032 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0051 | 0.0107 | 0.2083 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0358 | 0.1309 | 0.6451 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0055 | 0.0121 | 0.0289 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.0445 | 0.1102 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0138 | 0.0445 | 0.1041 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0126 | 0.04 | 0.0931 |
Schistosoma mansoni | jumonji domain containing protein | 0.008 | 0.0219 | 0.0524 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.009 | 0.0258 | 0.5988 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.038 | 0.1396 | 0.6897 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0293 | 0.1053 | 0.3955 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0126 | 0.04 | 0.0945 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0326 | 0.0763 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0237 | 0.0833 | 0.402 |
Loa Loa (eye worm) | hypothetical protein | 0.0602 | 0.2263 | 0.5514 |
Mycobacterium ulcerans | beta-lactamase | 0.0107 | 0.0326 | 0.1424 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.0667 | 0.1672 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0298 | 0.1075 | 0.4041 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0399 | 0.1468 | 0.3564 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0107 | 0.0326 | 0.0763 |
Echinococcus granulosus | peregrin | 0.0031 | 0.0026 | 0.0013 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.009 | 0.0258 | 0.0597 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.011 | 0.0337 | 0.1139 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.0256 | 0.0236 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.011 | 0.0337 | 0.1481 |
Echinococcus granulosus | GPCR family 2 | 0.0126 | 0.04 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0499 | 0.1188 |
Leishmania major | hypothetical protein, conserved | 0.013 | 0.0413 | 1 |
Loa Loa (eye worm) | fatty acid synthase | 0.0353 | 0.129 | 0.3128 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0107 | 0.0326 | 0.1424 |
Brugia malayi | beta-lactamase family protein | 0.0107 | 0.0326 | 0.0796 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.009 | 0.0258 | 0.1076 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.014 | 0.0119 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.0326 | 0.1095 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0136 | 0.0439 | 0.0419 |
Entamoeba histolytica | hypothetical protein | 0.0149 | 0.0487 | 1 |
Onchocerca volvulus | 0.0032 | 0.0032 | 0.0039 | |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks4 | 0.0055 | 0.0121 | 0.0289 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0151 | 0.0499 | 0.1175 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.014 | 0.0472 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0026 | 0.0005 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.009 | 0.0258 | 0.5834 |
Echinococcus multilocularis | muscleblind protein 1 | 0.1069 | 0.4092 | 0.408 |
Loa Loa (eye worm) | hypothetical protein | 0.1069 | 0.4092 | 1 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0108 | 0.0328 | 0.0802 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0326 | 0.0763 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.004 | 0.0045 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0026 | 0.003 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0288 | 0.1035 | 0.5049 |
Onchocerca volvulus | Acyl carrier protein, mitochondrial homolog | 0.0036 | 0.0047 | 0.0072 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0194 | 0.0379 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0101 | 0.03 | 0.028 |
Schistosoma mansoni | hypothetical protein | 0.0058 | 0.0133 | 0.0304 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0066 | 0.01 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.009 | 0.0258 | 0.0582 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0232 | 0.0816 | 0.5765 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0288 | 0.1035 | 0.5049 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0485 | 0.1153 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.014 | 0.2661 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0126 | 0.04 | 0.0977 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0123 | 0.0388 | 0.134 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0535 | 0.2003 | 0.769 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.0134 | 0.0785 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0036 | 0.0047 | 0.0154 |
Plasmodium vivax | hypothetical protein, conserved | 0.0107 | 0.0326 | 0.6336 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0021 | 0.0016 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0138 | 0.0445 | 0.0425 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0138 | 0.0445 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0121 | 0.0261 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0194 | 0.0459 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0107 | 0.0326 | 0.0749 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.0285 | 0.0692 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.0067 | 0.0164 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0107 | 0.0326 | 0.1095 |
Treponema pallidum | acyl carrier protein | 0.0036 | 0.0047 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0107 | 0.0326 | 0.1424 |
Trypanosoma cruzi | Acyl carrier protein, mitochondrial, putative | 0.0036 | 0.0047 | 0.0184 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0107 | 0.0326 | 0.0797 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0014 | 0.0035 |
Brugia malayi | beta-lactamase family protein | 0.0107 | 0.0326 | 0.0796 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0107 | 0.0326 | 0.1095 |
Mycobacterium leprae | PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 | 0.0055 | 0.0121 | 0.0376 |
Echinococcus granulosus | AMP dependent ligase | 0.0036 | 0.0047 | 0.0065 |
Brugia malayi | acyl carrier protein, mitochondrial precursor, putative | 0.0036 | 0.0047 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0326 | 0.0763 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.0026 | 0.0064 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0288 | 0.1035 | 0.5049 |
Entamoeba histolytica | hypothetical protein | 0.0149 | 0.0487 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0151 | 0.0499 | 0.0479 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0107 | 0.0326 | 0.0668 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.009 | 0.0258 | 0.1076 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0399 | 0.1468 | 0.3587 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.013 | 0.0413 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0047 | 0.0084 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.014 | 0.0292 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0079 | 0.0141 |
Schistosoma mansoni | rotamase | 0.0035 | 0.0044 | 0.0075 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0095 | 0.0279 | 0.0682 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0149 | 0.0487 | 0.1146 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0358 | 0.1309 | 0.3198 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0067 | 0.0103 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0399 | 0.1468 | 0.3587 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.0326 | 0.1095 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0151 | 0.0499 | 0.1241 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.009 | 0.0258 | 1 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0347 | 0.1266 | 0.4791 |
Echinococcus multilocularis | AMP dependent ligase | 0.0036 | 0.0047 | 0.0027 |
Mycobacterium ulcerans | thioesterase | 0.0298 | 0.1075 | 0.5255 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0298 | 0.1075 | 0.5255 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.013 | 0.0413 | 0.2824 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0138 | 0.0445 | 0.0425 |
Loa Loa (eye worm) | acyl carrier protein | 0.0165 | 0.0551 | 0.1315 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.013 | 0.0413 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0107 | 0.0326 | 0.0306 |
Onchocerca volvulus | 0.0107 | 0.0326 | 0.0679 | |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0079 | 0.013 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.009 | 0.0258 | 0.4898 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0026 | 0.0029 |
Trichomonas vaginalis | esterase, putative | 0.0107 | 0.0326 | 0.0668 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0685 | 0.259 | 1 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.038 | 0.1396 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.04 | 0.0987 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.0256 | 0.0579 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.009 | 0.0258 | 0.1076 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0347 | 0.1266 | 0.4791 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0064 | 0.0154 | 0.0343 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0107 | 0.0326 | 0.0668 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0535 | 0.2003 | 0.769 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.006 | 0.0117 |
Echinococcus multilocularis | GPCR, family 2 | 0.0126 | 0.04 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0066 | 0.0126 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0035 | 0.0044 | 0.0072 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0095 | 0.0279 | 0.0259 |
Brugia malayi | beta-lactamase | 0.0107 | 0.0326 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0326 | 0.0763 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0107 | 0.0326 | 0.766 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0107 | 0.0326 | 0.766 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0067 | 0.0103 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0026 | 0.0013 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0095 | 0.0279 | 0.5335 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.0445 | 0.1102 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0107 | 0.0326 | 0.0668 |
Brugia malayi | jmjC domain containing protein | 0.0101 | 0.03 | 0.0734 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0067 | 0.0129 |
Echinococcus granulosus | acyl carrier protein mitochondrial | 0.0036 | 0.0047 | 0.0065 |
Mycobacterium ulcerans | polyketide synthase | 0.038 | 0.1396 | 0.6897 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0067 | 0.0115 |
Brugia malayi | hypothetical protein | 0.0148 | 0.0485 | 0.1185 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0164 | 0.0546 | 0.1362 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0335 | 0.1216 | 0.4598 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0066 | 0.0111 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0151 | 0.0499 | 0.3453 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0058 | 0.0111 |
Brugia malayi | Heterochromatin protein 1 | 0.0074 | 0.0194 | 0.0473 |
Mycobacterium tuberculosis | Conserved protein | 0.0107 | 0.0326 | 0.1095 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0107 | 0.0326 | 0.0668 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0237 | 0.0833 | 0.402 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 0.0973 | 0.2352 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.038 | 0.1396 | 0.5303 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0126 | 0.04 | 0.038 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.013 | 0.0413 | 0.8179 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0088 | 0.0248 | 0.0791 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0358 | 0.1309 | 0.6451 |
Onchocerca volvulus | 0.1198 | 0.4598 | 1 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.013 | 0.0413 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0107 | 0.0326 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.0692 | 0.1661 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0149 | 0.0487 | 0.1211 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.04 | 0.0987 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0095 | 0.0279 | 0.0634 |
Brugia malayi | Pre-SET motif family protein | 0.0151 | 0.0499 | 0.122 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0279 | 0.0649 |
Echinococcus multilocularis | Acyl carrier protein, mitochondrial | 0.0036 | 0.0047 | 0.0027 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0145 | 0.0473 | 0.1674 |
Brugia malayi | hypothetical protein | 0.0084 | 0.0233 | 0.057 |
Onchocerca volvulus | 0.0107 | 0.0326 | 0.0679 | |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0358 | 0.1309 | 0.6451 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0138 | 0.0445 | 0.1087 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0335 | 0.1216 | 0.2948 |
Trichomonas vaginalis | rotamase, putative | 0.0035 | 0.0044 | 0.0052 |
Brugia malayi | Muscleblind-like protein | 0.1069 | 0.4092 | 1 |
Echinococcus multilocularis | expressed protein | 0.0035 | 0.0044 | 0.0023 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.009 | 0.0258 | 0.5834 |
Leishmania major | acyl carrier protein, putative | 0.0036 | 0.0047 | 0.0184 |
Schistosoma mansoni | hypothetical protein | 0.1024 | 0.3919 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0079 | 0.013 |
Schistosoma mansoni | hypothetical protein | 0.1024 | 0.3919 | 1 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0066 | 0.0045 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0679 | 0.2565 | 0.6269 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0257 | 0.0913 | 0.3406 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0138 | 0.0445 | 0.1055 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.0667 | 0.1672 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.009 | 0.0258 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.1069 | 0.4092 | 0.408 |
Loa Loa (eye worm) | TAR-binding protein | 0.0194 | 0.0667 | 0.1601 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.038 | 0.1396 | 0.6897 |
Brugia malayi | Pre-SET motif family protein | 0.1053 | 0.4029 | 0.9846 |
Brugia malayi | TAR-binding protein | 0.0194 | 0.0667 | 0.1631 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0237 | 0.0833 | 0.402 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.009 | 0.0258 | 0.5834 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0358 | 0.1309 | 0.4961 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0145 | 0.0475 | 0.1116 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.038 | 0.1396 | 0.6897 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0358 | 0.1309 | 0.4961 |
Echinococcus multilocularis | NADH dehydrogenase | 0.0036 | 0.0047 | 0.0027 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.009 | 0.0258 | 0.5834 |
Brugia malayi | jmjC domain containing protein | 0.0039 | 0.0058 | 0.0141 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0073 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0273 | 0.0973 | 0.2456 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0107 | 0.0326 | 0.1095 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0039 | 0.0058 | 0.0091 |
Echinococcus granulosus | geminin | 0.1024 | 0.3919 | 0.9575 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0194 | 0.0173 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0107 | 0.0326 | 0.1095 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0101 | 0.03 | 0.0687 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0358 | 0.1309 | 0.4961 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0328 | 0.1105 |
Giardia lamblia | Methyltransferase like 2 | 0.0108 | 0.0328 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0194 | 0.0667 | 0.1588 |
Onchocerca volvulus | 0.0107 | 0.0326 | 0.0679 | |
Echinococcus granulosus | NADH dehydrogenase | 0.0036 | 0.0047 | 0.0065 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0066 | 0.0111 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0034 | 0.004 | 0.0104 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.006 | 0.0117 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0107 | 0.0326 | 0.766 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.013 | 0.0413 | 1 |
Trypanosoma brucei | Acyl carrier protein, mitochondrial | 0.0036 | 0.0047 | 0.0184 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0535 | 0.2003 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0149 | 0.0487 | 1 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.009 | 0.0258 | 0.0238 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0204 | 0.0703 | 0.258 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0032 | 0.0043 |
Toxoplasma gondii | ABC1 family protein | 0.0107 | 0.0326 | 0.2188 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0326 | 0.0763 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.1053 | 0.4029 | 0.9845 |
Loa Loa (eye worm) | acyl carrier protein | 0.0036 | 0.0047 | 0.008 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0194 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.1069 | 0.4092 | 1 |
Brugia malayi | RNA binding protein | 0.0194 | 0.0667 | 0.1631 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.014 | 0.0472 |
Onchocerca volvulus | 0.0164 | 0.0546 | 0.116 | |
Mycobacterium ulcerans | hypothetical protein | 0.0107 | 0.0326 | 0.1424 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0066 | 0.0126 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0126 | 0.04 | 0.0977 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.014 | 0.0363 |
Echinococcus multilocularis | geminin | 0.1024 | 0.3919 | 0.3906 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.0667 | 0.1672 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.0158 | 0.0368 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0151 | 0.0499 | 0.0479 |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0.0026 | 0.0025 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.009 | 0.0258 | 0.1691 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0035 | 0.0044 | 0.0107 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0036 | 0.0047 | 0.0154 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0058 | 0.0133 | 0.0113 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0535 | 0.2003 | 1 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0358 | 0.1309 | 0.6451 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0194 | 0.0173 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.013 | 0.0413 | 1 |
Schistosoma mansoni | methyltransferase-related | 0.0108 | 0.0328 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0399 | 0.1468 | 0.3564 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.038 | 0.1396 | 0.5303 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0255 | 0.0904 | 0.6412 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.009 | 0.0258 | 0.063 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0113 | 0.0346 | 0.1176 |
Entamoeba histolytica | hypothetical protein | 0.0149 | 0.0487 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.014 | 0.0472 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0194 | 0.0667 | 0.1631 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0107 | 0.0326 | 0.1095 |
Brugia malayi | hypothetical protein | 0.0149 | 0.0487 | 0.1191 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0026 | 0.003 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0088 | 0.0068 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.0667 | 0.1672 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0273 | 0.0973 | 0.2379 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0358 | 0.1309 | 0.6451 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0107 | 0.0326 | 0.0797 |
Brugia malayi | hypothetical protein | 0.013 | 0.0413 | 0.1009 |
Trichomonas vaginalis | set domain proteins, putative | 0.1198 | 0.4598 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0107 | 0.0326 | 0.0763 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0107 | 0.0326 | 0.1424 |
Leishmania major | hypothetical protein, conserved | 0.0107 | 0.0326 | 0.766 |
Schistosoma mansoni | acyl carrier protein | 0.0036 | 0.0047 | 0.0084 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.006 | 0.0117 |
Echinococcus multilocularis | tar DNA binding protein | 0.0194 | 0.0667 | 0.0648 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0021 | 0.0016 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0194 | 0.0667 | 0.1601 |
Onchocerca volvulus | 0.0036 | 0.0047 | 0.0072 | |
Mycobacterium leprae | Probable lipase LipE | 0.0107 | 0.0326 | 0.1424 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0058 | 0.0133 | 0.0276 |
Mycobacterium ulcerans | polyketide synthase | 0.0358 | 0.1309 | 0.6451 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0151 | 0.0499 | 0.1241 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0026 | 0.0064 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.0445 | 0.1102 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.038 | 0.1396 | 0.6897 |
Brugia malayi | Phosphopantetheine attachment site family protein | 0.0036 | 0.0047 | 0.0116 |
Loa Loa (eye worm) | phosphopantetheine attachment site family protein | 0.0036 | 0.0047 | 0.008 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.0026 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.04 | 0.0945 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.006 | 0.0117 |
Brugia malayi | AMP-binding enzyme family protein | 0.011 | 0.0337 | 0.0824 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0194 | 0.0425 |
Mycobacterium ulcerans | lipase LipD | 0.0107 | 0.0326 | 0.1424 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0039 | 0.0058 | 0.0106 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.04 | 0.0987 |
Plasmodium vivax | acyl carrier protein, putative | 0.0036 | 0.0047 | 0.0448 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.038 | 0.1396 | 0.6897 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0066 | 0.0045 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0051 | 0.0031 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0036 | 0.0047 | 0.0116 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0108 | 0.0328 | 0.1105 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0136 | 0.0439 | 0.1028 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0113 | 0.0346 | 0.1529 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0107 | 0.0326 | 0.1095 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0039 | 0.0058 | 0.0111 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.038 | 0.1396 | 0.5303 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0112 | 0.024 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0107 | 0.0326 | 0.1095 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0073 | 0.0129 |
Mycobacterium ulcerans | thioesterase TesA | 0.0298 | 0.1075 | 0.5255 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0121 | 0.0261 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0107 | 0.0326 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0413 | 0.0977 |
Echinococcus granulosus | muscleblind protein | 0.1069 | 0.4092 | 1 |
Toxoplasma gondii | acyl carrier protein ACP | 0.0036 | 0.0047 | 0.0155 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0194 | 0.0379 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0044 | 0.0052 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.04 | 0.0987 |
Plasmodium vivax | hypothetical protein, conserved | 0.0051 | 0.0107 | 0.1704 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0126 | 0.04 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0326 | 0.0763 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0149 | 0.0487 | 0.0468 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0194 | 0.0425 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0126 | 0.04 | 0.038 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0358 | 0.1309 | 0.6451 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0102 | 0.0214 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.009 | 0.0258 | 0.0623 |
Schistosoma mansoni | tar DNA-binding protein | 0.0194 | 0.0667 | 0.1672 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0646 | 0.2435 | 0.528 |
Leishmania major | hypothetical protein, conserved | 0.0108 | 0.0328 | 0.7727 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.014 | 0.0828 |
Echinococcus granulosus | expressed protein | 0.0035 | 0.0044 | 0.0056 |
Onchocerca volvulus | 0.0623 | 0.2348 | 0.509 | |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks3 | 0.0055 | 0.0121 | 0.0289 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0074 | 0.0194 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0026 | 0.0029 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.014 | 0.032 |
Loa Loa (eye worm) | RNA binding protein | 0.0194 | 0.0667 | 0.1601 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.0113 | 0.0346 | 0.1529 |
Toxoplasma gondii | type I fatty acid synthase | 0.0055 | 0.0121 | 0.0691 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0181 | 0.0615 | 0.4297 |
Plasmodium vivax | SET domain protein, putative | 0.0151 | 0.0499 | 1 |
Onchocerca volvulus | 0.0148 | 0.0485 | 0.1026 | |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0066 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.0487 | 0.1211 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0066 | 0.0161 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0151 | 0.0499 | 0.1241 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.