Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0025 | 0.2282 | 0.2282 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.2624 | 0.2624 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2521 | 0.2521 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.2624 | 0.2624 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.2282 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.2282 | 0.5 |
Onchocerca volvulus | 0.0027 | 0.2624 | 0.5 | |
Brugia malayi | TAR-binding protein | 0.0062 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.2282 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.2282 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.2624 | 0.2624 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.2624 | 0.2624 |
Onchocerca volvulus | 0.0027 | 0.2624 | 0.5 | |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.04 | 0.04 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 1 | 1 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.2624 | 0.2624 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.2282 | 0.2282 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.2282 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.2282 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.2282 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.2282 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.