Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Bile acid receptor homolog | 0.0012 | 0 | 0.5 |
Brugia malayi | RNA binding protein | 0.0073 | 0.3341 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3341 | 0.3341 |
Echinococcus granulosus | tar DNA binding protein | 0.0073 | 0.3341 | 0.3341 |
Schistosoma mansoni | hypothetical protein | 0.0194 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0073 | 0.3341 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0073 | 0.3341 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.2236 | 0.6693 |
Onchocerca volvulus | 0.0012 | 0 | 0.5 | |
Brugia malayi | RNA recognition motif domain containing protein | 0.0073 | 0.3341 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.2236 | 0.2236 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0012 | 0 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.2236 | 0.2236 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0012 | 0 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0073 | 0.3341 | 0.3341 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.2236 | 0.2236 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.2236 | 0.2236 |
Loa Loa (eye worm) | TAR-binding protein | 0.0073 | 0.3341 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.2236 | 0.2236 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.2236 | 0.6693 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3341 | 0.3341 |
Schistosoma mansoni | hypothetical protein | 0.0194 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0194 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.2236 | 0.2236 |
Brugia malayi | TAR-binding protein | 0.0073 | 0.3341 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3341 | 0.3341 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3341 | 0.3341 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3341 | 0.3341 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.2236 | 0.2236 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
T1/2 (ADMET) | = 88 min | Half life in human plasma | ChEMBL. | 19398207 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.