Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0034 | 0.0482 | 0.0984 |
Wolbachia endosymbiont of Brugia malayi | metallo-beta-lactamase superfamily hydrolase | 0.0034 | 0.0482 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.007 | 0.0076 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0127 | 0.3476 | 0.3476 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0124 | 0.3368 | 1 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0124 | 0.3368 | 0.471 |
Echinococcus granulosus | geminin | 0.0168 | 0.4804 | 0.4804 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0034 | 0.0482 | 0.0347 |
Schistosoma mansoni | lipoxygenase | 0.0089 | 0.2245 | 0.314 |
Echinococcus granulosus | tar DNA binding protein | 0.0208 | 0.6097 | 0.6097 |
Echinococcus multilocularis | hydroxyacylglutathione hydrolase | 0.0034 | 0.0482 | 0.0482 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.007 | 0.007 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.7151 | 1 |
Trypanosoma brucei | metallo-beta-lactamase-like protein, putative | 0.0034 | 0.0482 | 0.0984 |
Trypanosoma brucei | glyoxalase II | 0.0034 | 0.0482 | 0.0984 |
Brugia malayi | Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. | 0.0034 | 0.0482 | 0.0449 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0044 | 0.0804 | 0.0703 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0044 | 0.0804 | 0.2226 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0124 | 0.3368 | 0.3597 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0034 | 0.0482 | 0.0984 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Brugia malayi | Heterochromatin protein 1 | 0.0078 | 0.1893 | 0.1989 |
Echinococcus multilocularis | muscleblind protein | 0.0158 | 0.4474 | 0.4474 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0124 | 0.3368 | 0.471 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0124 | 0.3368 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0262 | 0.7834 | 0.8481 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0057 | 0.0062 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.7151 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0262 | 0.7834 | 0.8481 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0241 | 0.7151 | 0.7151 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0124 | 0.3368 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.1893 | 0.1893 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0024 | 0.0167 | 0.0105 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0241 | 0.7164 | 0.7756 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Plasmodium vivax | unspecified product | 0.0034 | 0.0482 | 0.1248 |
Trichomonas vaginalis | A-type flavoprotein | 0.0034 | 0.0482 | 0.0347 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0047 | 0.0898 | 0.1433 |
Onchocerca volvulus | 0.012 | 0.3242 | 0.5489 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0381 | 0.0237 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0034 | 0.0482 | 0.0482 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0124 | 0.3368 | 0.3368 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0044 | 0.0804 | 0.1992 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0061 | 0.134 | 0.1385 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0211 | 0.6198 | 0.6649 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0208 | 0.6097 | 0.66 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0124 | 0.3368 | 0.3368 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0034 | 0.0482 | 0.0984 |
Trypanosoma cruzi | glyoxalase II | 0.0034 | 0.0482 | 0.1282 |
Plasmodium vivax | hydroxyacyl glutathione hydrolase, putative | 0.0034 | 0.0482 | 0.1248 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0306 | 0.9237 | 1 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0034 | 0.0482 | 0.0674 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.007 | 0.1646 | 0.1646 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0482 | 0.0674 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0241 | 0.7151 | 0.7151 |
Brugia malayi | Rhodanese-like domain containing protein | 0.012 | 0.3242 | 0.346 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0034 | 0.0482 | 0.0984 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0124 | 0.3368 | 0.3529 |
Trypanosoma brucei | hydroxyacylglutathione hydrolase, putative | 0.0034 | 0.0482 | 0.0984 |
Schistosoma mansoni | zinc finger protein | 0.0025 | 0.0202 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0963 | 0.1043 |
Brugia malayi | MH2 domain containing protein | 0.0262 | 0.7834 | 0.8469 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0124 | 0.3368 | 0.3368 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0034 | 0.0482 | 0.0482 |
Echinococcus granulosus | m phase inducer phosphatasecdc25 | 0.012 | 0.3242 | 0.3242 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0124 | 0.3368 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0381 | 0.0237 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.012 | 0.3242 | 0.3391 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0061 | 0.134 | 0.134 |
Brugia malayi | Bromodomain containing protein | 0.0046 | 0.0876 | 0.0879 |
Echinococcus granulosus | zinc phosphodiesterase | 0.0034 | 0.0482 | 0.0482 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.1893 | 0.1904 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0792 | 0.0689 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0078 | 0.1893 | 0.205 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0488 | 0.0528 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0061 | 0.134 | 0.2348 |
Brugia malayi | RNA binding protein | 0.0208 | 0.6097 | 0.6574 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.007 | 0.007 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0449 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.1893 | 0.1893 |
Onchocerca volvulus | 0.0034 | 0.0482 | 0.0712 | |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0306 | 0.9237 | 1 |
Loa Loa (eye worm) | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0521 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0609 | 0.0588 |
Echinococcus multilocularis | m phase inducer phosphatase(cdc25) | 0.012 | 0.3242 | 0.3242 |
Schistosoma mansoni | loxhd1 | 0.0021 | 0.007 | 0.0098 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0124 | 0.3368 | 0.3529 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0127 | 0.3476 | 0.3476 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0024 | 0.0167 | 0.0167 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.012 | 0.3242 | 0.9608 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0124 | 0.3368 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.3368 | 0.3646 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0609 | 0.0659 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0025 | 0.0198 | 0.0198 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0124 | 0.3368 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0241 | 0.7151 | 0.7151 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0044 | 0.0804 | 0.1992 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0167 | 0.033 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0241 | 0.7151 | 0.7151 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0118 | 0.0127 |
Chlamydia trachomatis | ribonuclease Z | 0.0034 | 0.0482 | 0.5 |
Echinococcus multilocularis | RUN | 0.0021 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3242 | 0.351 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.012 | 0.3242 | 0.3391 |
Plasmodium vivax | RNA helicase-1, putative | 0.0124 | 0.3368 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.007 | 0.007 |
Brugia malayi | Rhodanese-like domain containing protein | 0.012 | 0.3242 | 0.346 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.012 | 0.3242 | 0.3391 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.0898 | 0.0807 |
Echinococcus granulosus | RUN | 0.0021 | 0.007 | 0.007 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0158 | 0.4474 | 0.4474 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.0679 | 0.0679 |
Schistosoma mansoni | bromodomain containing protein | 0.0074 | 0.1775 | 0.2482 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.094 | 0.1314 |
Brugia malayi | ethe1-prov protein | 0.0034 | 0.0482 | 0.0449 |
Echinococcus multilocularis | tar DNA binding protein | 0.0208 | 0.6097 | 0.6097 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.007 | 0.007 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0482 | 0.0449 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.007 | 0.0098 |
Onchocerca volvulus | 0.0034 | 0.0482 | 0.0712 | |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0061 | 0.134 | 0.1874 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4804 | 0.6718 |
Loa Loa (eye worm) | doublecortin family protein | 0.0021 | 0.007 | 0.0076 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0034 | 0.0482 | 0.0984 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0124 | 0.3368 | 1 |
Echinococcus granulosus | hydroxyacylglutathione hydrolase | 0.0034 | 0.0482 | 0.0482 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0061 | 0.134 | 0.2348 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0061 | 0.134 | 0.2348 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.007 | 0.0098 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.0679 | 0.0679 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.012 | 0.3242 | 0.9608 |
Brugia malayi | TAR-binding protein | 0.0208 | 0.6097 | 0.6574 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0608 | 0.1631 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0034 | 0.0482 | 0.0347 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.0898 | 0.0807 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0034 | 0.0482 | 0.0674 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0124 | 0.3368 | 1 |
Mycobacterium tuberculosis | Class a beta-lactamase BlaC | 0.0147 | 0.4138 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0241 | 0.7151 | 0.7724 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0482 | 0.0521 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0124 | 0.3368 | 0.3529 |
Echinococcus multilocularis | geminin | 0.0168 | 0.4804 | 0.4804 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0482 | 0.0674 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0044 | 0.0804 | 0.0703 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0394 | 0.0353 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0034 | 0.0482 | 0.0984 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0792 | 0.1249 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 0.1117 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3242 | 0.351 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqF | 0.0071 | 0.1667 | 0.3243 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0792 | 0.0689 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.4474 | 0.4843 |
Echinococcus multilocularis | zinc finger protein | 0.0025 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.4474 | 0.4843 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0021 | 0.007 | 0.007 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0021 | 0.007 | 0.007 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0118 | 0.0052 |
Loa Loa (eye worm) | RNA binding protein | 0.0208 | 0.6097 | 0.66 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0143 | 0.4003 | 0.429 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.094 | 0.1017 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.1893 | 0.2648 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1931 | 0.2091 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.1174 | 0.1205 |
Plasmodium falciparum | cytosolic glyoxalase II | 0.0034 | 0.0482 | 0.1248 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0034 | 0.0482 | 0.0482 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0034 | 0.0482 | 0.1282 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.1893 | 0.1893 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.1893 | 0.1893 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0023 | 0.0129 | 0.0139 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.3791 | 0.3791 |
Onchocerca volvulus | 0.012 | 0.3242 | 0.5489 | |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0061 | 0.134 | 0.2974 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0025 | 0.0198 | 0.0198 |
Onchocerca volvulus | 0.0048 | 0.094 | 0.1505 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.7151 | 1 |
Echinococcus granulosus | serine protein kinase ATM | 0.0024 | 0.0167 | 0.0167 |
Toxoplasma gondii | metallo-beta-lactamase domain-containing protein | 0.0034 | 0.0482 | 0.0984 |
Trypanosoma brucei | cleavage and polyadenylation specificity factor subunit, putative | 0.0034 | 0.0482 | 0.0984 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0034 | 0.0482 | 0.1282 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Echinococcus multilocularis | ETHE1 protein | 0.0034 | 0.0482 | 0.0482 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0044 | 0.0804 | 0.0804 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0034 | 0.0482 | 0.1282 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.1893 | 0.2648 |
Schistosoma mansoni | m-phase inducer phosphatase(cdc25) | 0.012 | 0.3242 | 0.4534 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0023 | 0.0133 | 0.0144 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.012 | 0.3242 | 0.9608 |
Echinococcus granulosus | zinc finger protein | 0.0025 | 0.0202 | 0.0202 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0143 | 0.4003 | 0.4003 |
Echinococcus granulosus | ETHE1 protein | 0.0034 | 0.0482 | 0.0482 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0034 | 0.0482 | 0.0482 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0024 | 0.0167 | 0.0233 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0034 | 0.0482 | 0.0984 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0124 | 0.3368 | 0.3368 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0792 | 0.0857 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0608 | 0.1379 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0143 | 0.4003 | 0.5598 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0061 | 0.134 | 0.134 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.1893 | 0.1904 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0449 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0124 | 0.3368 | 1 |
Trypanosoma brucei | beta lactamase | 0.0071 | 0.1667 | 0.4688 |
Schistosoma mansoni | polycystin 1-related | 0.0021 | 0.007 | 0.0098 |
Echinococcus multilocularis | zinc phosphodiesterase | 0.0034 | 0.0482 | 0.0482 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase cytoplasmic | 0.0034 | 0.0482 | 0.0521 |
Onchocerca volvulus | 0.0034 | 0.0488 | 0.0723 | |
Brugia malayi | follicle stimulating hormone receptor | 0.0241 | 0.7164 | 0.7738 |
Trypanosoma cruzi | glyoxalase II | 0.0034 | 0.0482 | 0.1282 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0211 | 0.6198 | 0.6649 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.012 | 0.3242 | 0.3391 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Echinococcus granulosus | muscleblind protein | 0.0158 | 0.4474 | 0.4474 |
Mycobacterium ulcerans | class a beta-lactamase, BlaC | 0.0147 | 0.4138 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0241 | 0.7151 | 0.7741 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.1174 | 0.1271 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1174 | 0.1271 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0034 | 0.0482 | 0.0984 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4804 | 0.6718 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0767 | 0.083 |
Loa Loa (eye worm) | acetyltransferase | 0.0143 | 0.4003 | 0.4334 |
Onchocerca volvulus | 0.012 | 0.3242 | 0.5489 | |
Trichomonas vaginalis | cdc25c, putative | 0.012 | 0.3242 | 0.3391 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Schistosoma mansoni | hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) | 0.0034 | 0.0482 | 0.0674 |
Toxoplasma gondii | hydroxyacylglutathione hydrolase | 0.0034 | 0.0482 | 0.0984 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0129 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0482 | 0.0521 |
Trichomonas vaginalis | cdc25b, putative | 0.012 | 0.3242 | 0.3391 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0208 | 0.6097 | 0.6574 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.007 | 0.1646 | 0.1646 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.007 | 0.0076 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0198 | 0.0276 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0984 |
Loa Loa (eye worm) | TAR-binding protein | 0.0208 | 0.6097 | 0.66 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.1174 | 0.1205 |
Mycobacterium ulcerans | lipoprotein LpqF | 0.0071 | 0.1667 | 0.3243 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0201 | 0.585 | 1 |
Onchocerca volvulus | Hydroxyacylglutathione hydrolase, mitochondrial homolog | 0.0034 | 0.0482 | 0.0712 |
Echinococcus multilocularis | tumor protein p63 | 0.0329 | 1 | 1 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0124 | 0.3368 | 0.5706 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0034 | 0.0482 | 0.1282 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQF | 0.0071 | 0.1667 | 1 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase | 0.0034 | 0.0482 | 0.0521 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.0124 | 0.3368 | 0.7893 |
Schistosoma mansoni | lipoxygenase | 0.0127 | 0.3476 | 0.4861 |
Trichomonas vaginalis | cdc25b, putative | 0.012 | 0.3242 | 0.3391 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.2941 | 0.3184 |
Onchocerca volvulus | Putative hydrolase PNKD | 0.0034 | 0.0482 | 0.0712 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0609 | 0.0851 |
Onchocerca volvulus | 0.012 | 0.3242 | 0.5489 | |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0057 | 0.1209 | 0.1308 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0984 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Brugia malayi | Bromodomain containing protein | 0.0087 | 0.2196 | 0.2319 |
Brugia malayi | chromobox protein homolog 3 | 0.0044 | 0.0792 | 0.0787 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0608 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0482 | 0.0521 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0034 | 0.0482 | 0.1282 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0482 | 0.0674 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.007 | 0.0098 |
Brugia malayi | Muscleblind-like protein | 0.0158 | 0.4474 | 0.4804 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.012 | 0.3242 | 0.3391 |
Trypanosoma cruzi | glyoxalase II | 0.0034 | 0.0482 | 0.1282 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0482 | 0.0521 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0034 | 0.0482 | 0.1282 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0124 | 0.3368 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.2941 | 0.3184 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.5 ug ml-1 | In vitro minimum inhibitory concentration against E. coli J3272 (tet D efflux). | ChEMBL. | 8289194 |
MIC (functional) | = 1 ug ml-1 | In vitro minimum inhibitory concentration against E. coli UBMS 88-1 (tet B efflux). | ChEMBL. | 8289194 |
MIC (functional) | = 1 ug ml-1 | In vitro minimum inhibitory concentration against E. coli UBMS 90-4 (tet M ribosomal protection). | ChEMBL. | 8289194 |
MIC (functional) | = 2 ug ml-1 | In vitro minimum inhibitory concentration against E. coli UBMS 90-5 (sensitive). | ChEMBL. | 8289194 |
MIC (functional) | = 4 ug ml-1 | In vitro minimum inhibitory concentration against E. coli J3272 (tet C efflux). | ChEMBL. | 8289194 |
MIC (functional) | = 8 ug ml-1 | In vitro minimum inhibitory concentration against E. coli PRP-1 (tet A efflux). | ChEMBL. | 8289194 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.