Detailed information for compound 1036121

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 352.817 | Formula: C19H17ClN4O
  • H donors: 2 H acceptors: 2 LogP: 3.53 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CCC(=NN1)c1ccc(cc1)Nc1ccnc2c1cccc2.Cl
  • InChi: 1S/C19H16N4O.ClH/c24-19-10-9-16(22-23-19)13-5-7-14(8-6-13)21-18-11-12-20-17-4-2-1-3-15(17)18;/h1-8,11-12H,9-10H2,(H,20,21)(H,23,24);1H
  • InChiKey: HWACTOXPJLXVPY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0133 0.1215
Mycobacterium ulcerans hypothetical protein 0.0025 0.0027 0.0237
Schistosoma mansoni twik family of potassium channels-related 0.0066 0.0176 0.0175
Onchocerca volvulus 0.0066 0.0176 0.0938
Leishmania major hypothetical protein, conserved 0.0066 0.0176 0.1609
Onchocerca volvulus 0.0064 0.0171 0.0905
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0023 0.1112
Treponema pallidum 76K protein 0.0027 0.0036 0.087
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0049 0.0115 0.0114
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0011 0.0009
Schistosoma mansoni nuclear hormone receptor 0.002 0.0011 0.0009
Echinococcus multilocularis Smad4 0.0034 0.0061 0.0059
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0149 0.0147
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0012
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.001
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0005 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Leishmania major hypothetical protein, conserved 0.0035 0.0064 0.0557
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0064 0.0063
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0067 0.018 0.0178
Toxoplasma gondii RNA-directed DNA polymerase 0.0083 0.0237 0.4758
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0061 0.0117
Brugia malayi hypothetical protein 0.002 0.0011 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0064 0.0062
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0011 0.0043
Brugia malayi Cathepsin L-like precursor 0.0035 0.0064 0.0351
Leishmania major cathepsin L-like protease 0.0035 0.0064 0.0553
Onchocerca volvulus 0.0027 0.0036 0.0144
Echinococcus granulosus cysteine protease 0.0018 0.0003 0.0002
Leishmania major pyruvate kinase 0.0034 0.0061 0.0528
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0027 0.0352
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0053
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0064 0.085
Loa Loa (eye worm) RecQ helicase 0.0043 0.0095 0.0183
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.0706 0.6581
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0061 0.0999
Leishmania major cathepsin L-like protease 0.0035 0.0064 0.0553
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0005 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0011 0.0009
Schistosoma mansoni metabotropic glutamate receptor 0.0021 0.0015 0.0013
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0061 0.0809
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0166 0.0319
Echinococcus granulosus ATP dependent DNA helicase Q1 0.003 0.0045 0.0044
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0053 0.013 0.025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Chlamydia trachomatis pyruvate kinase 0.0034 0.0061 1
Brugia malayi Cache domain containing protein 0.0293 0.0992 0.574
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0003 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.1071 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0035 0.0064 0.0122
Brugia malayi Bromodomain containing protein 0.0073 0.0203 0.1157
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.003 0.0045 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Schistosoma mansoni lamin 0.0139 0.0438 0.0437
Brugia malayi MH1 domain containing protein 0.0019 0.0006 0.0018
Loa Loa (eye worm) hypothetical protein 0.0152 0.0486 0.0933
Onchocerca volvulus Glucosylceramidase homolog 0.0177 0.0576 0.3199
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0576 0.3227
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0015 0.0108
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0661 0.2318 0.2316
Toxoplasma gondii ion channel protein 0.0066 0.0176 0.3532
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0118 0.0364 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0171 0.3415
Loa Loa (eye worm) hypothetical protein 0.0069 0.0188 0.036
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0176 0.1622
Plasmodium vivax vivapain-2 0.0035 0.0064 0.1255
Onchocerca volvulus 0.0027 0.0036 0.0144
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0086 0.0464
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0036 0.1897
Treponema pallidum hypothetical protein 0.0027 0.0036 0.087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0086 0.0084
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0005 0.0003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0022 0.0108
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0011 0.0009
Schistosoma mansoni microtubule-associated protein tau 0.2795 1 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Trichomonas vaginalis glutaminase, putative 0.0284 0.096 0.5391
Schistosoma mansoni hypothetical protein 0.0063 0.0166 0.0164
Loa Loa (eye worm) hypothetical protein 0.004 0.0082 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.003 0.0045 0.0044
Brugia malayi RNA recognition motif domain containing protein 0.0191 0.0626 0.3614
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0005 0.0112
Plasmodium falciparum potassium channel 0.0066 0.0176 0.3532
Onchocerca volvulus 0.0066 0.0176 0.0938
Echinococcus granulosus GPCR family 2 0.0063 0.0166 0.0164
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0066 0.0176 0.1005
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0027 0.0141
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0056 0.0491
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0066 0.0176 0.1005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0011 0.0009
Plasmodium falciparum ataxin-2 like protein, putative 0.0155 0.0496 1
Plasmodium vivax vivapain-3 0.0018 0.0003 0.0032
Echinococcus multilocularis pyruvate kinase 0.0034 0.0061 0.0059
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0003 0.0002
Echinococcus multilocularis serotonin receptor 0.0142 0.045 0.0449
Echinococcus granulosus zinc finger protein 0.0019 0.0008 0.0006
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0005 0.0009
Brugia malayi glutaminase DH11.1 0.0284 0.096 0.5552
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0027 0.0235
Echinococcus granulosus voltage dependent calcium channel subunit 0.0661 0.2318 0.2316
Brugia malayi Cathepsin L-like precursor 0.0035 0.0064 0.0351
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0064 0.03
Entamoeba histolytica hypothetical protein 0.0025 0.003 0.154
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Schistosoma mansoni twik family of potassium channels-related 0.0066 0.0176 0.0175
Schistosoma mansoni cellular tumor antigen P53 0.0152 0.0486 0.0484
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.001
Onchocerca volvulus 0.0511 0.1777 1
Schistosoma mansoni hypothetical protein 0.002 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0033
Leishmania major hypothetical protein, conserved 0.0066 0.0176 0.1609
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0231 0.0229
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Trypanosoma brucei hypothetical protein, conserved 0.0213 0.0706 0.6581
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0005 0.0004
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0022 0.0108
Echinococcus multilocularis muscleblind protein 1 0.0302 0.1024 0.1023
Loa Loa (eye worm) RNA binding protein 0.0191 0.0626 0.1202
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0015 0.0265
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0064 0.1263
Echinococcus granulosus expressed protein 0.0118 0.0364 0.0362
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0005 0.0064
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0149 0.0475 0.4416
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.0385 0.0384
Onchocerca volvulus 0.0035 0.0064 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0171 0.0169
Echinococcus multilocularis lamin 0.0139 0.0438 0.0437
Schistosoma mansoni lipoxygenase 0.0056 0.0141 0.0139
Brugia malayi hypothetical protein 0.0155 0.0496 0.2863
Brugia malayi Muscleblind-like protein 0.0302 0.1024 0.5928
Echinococcus multilocularis twik family of potassium channels 0.0066 0.0176 0.0175
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0061 0.059
Brugia malayi Zona pellucida-like domain containing protein 0.0027 0.0036 0.0191
Schistosoma mansoni thyroid hormone receptor 0.0142 0.045 0.0449
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0064 0.0122
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0066 0.0176 0.1622
Echinococcus multilocularis ferritin 0.0118 0.0364 0.0362
Entamoeba histolytica Ran family GTPase 0.0021 0.0015 0.0665
Loa Loa (eye worm) hypothetical protein 0.0302 0.1024 0.1968
Echinococcus granulosus calcium activated potassium channel variant 0.0066 0.0176 0.0175
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0231 0.0229
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0066 0.0176 0.1005
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0011 0.0192
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0061 0.1201
Loa Loa (eye worm) TAR-binding protein 0.0191 0.0626 0.1202
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0385 0.3987
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0011 0.0009
Onchocerca volvulus 0.0035 0.0064 0.0303
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0609 0.213 0.4092
Echinococcus granulosus voltage dependent calcium channel subunit 0.1453 0.5169 0.5168
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0576 0.3227
Echinococcus granulosus geminin 0.0176 0.0574 0.0572
Plasmodium vivax unspecified product 0.0018 0.0003 0.0032
Onchocerca volvulus 0.0027 0.0036 0.0144
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0149 0.0147
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0005 0.0018
Onchocerca volvulus 0.0025 0.0027 0.0095
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0141 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0005 0.0004
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0015 0.0028
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0475 0.4416
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0005 0.0005
Schistosoma mansoni twik family of potassium channels-related 0.0066 0.0176 0.0175
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0015 0.0265
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0011 0.0043
Leishmania major ion transport protein-like protein 0.0066 0.0176 0.1609
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0064 0.0343
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0449 0.1554 0.2985
Echinococcus granulosus Smad4 0.0034 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Mycobacterium ulcerans glutaminase 0.0284 0.096 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.0166 0.0164
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0005 0.0045
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0045 0.0245
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0064 0.0553
Leishmania major pyruvate kinase 0.0034 0.0061 0.0528
Echinococcus multilocularis microtubule associated protein 2 0.2795 1 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0025 0.0031 0.0586
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Echinococcus granulosus bloom syndrome protein 0.0043 0.0095 0.0094
Schistosoma mansoni ferritin light chain 0.0118 0.0364 0.0362
Plasmodium falciparum thrombospondin-related anonymous protein 0.0027 0.0036 0.0696
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0086 0.077
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0018 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0626 0.0624
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Giardia lamblia Hypothetical protein 0.0066 0.0176 0.7423
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0015 0.0013
Entamoeba histolytica elongation factor-2 kinase, putative 0.0027 0.0036 0.1897
Brugia malayi Importin beta-1 subunit 0.0029 0.0042 0.0225
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.032 0.1089 0.1088
Brugia malayi Cathepsin L-like precursor 0.0035 0.0064 0.0351
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.001
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0069 0.0189 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0023 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Echinococcus multilocularis voltage dependent calcium channel subunit 0.1453 0.5169 0.5168
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0064 0.1255
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0027 0.0235
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0066 0.0176 0.0976
Leishmania major calcium/potassium channel (CAKC), putative 0.0066 0.0176 0.1609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0066 0.0176 0.1622
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0027 0.035
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0118 0.0364 0.4916
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0064 0.0122
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0005 0.0009
Brugia malayi Intermediate filament tail domain containing protein 0.0139 0.0438 0.2527
Loa Loa (eye worm) CUTiclin-Like family member 0.0027 0.0036 0.0069
Schistosoma mansoni lipoxygenase 0.002 0.0011 0.001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0011 0.0043
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0064 0.03
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0061 0.0326
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0074 0.0207 0.0397
Loa Loa (eye worm) hypothetical protein 0.0678 0.2381 0.4573
Brugia malayi MH1 domain containing protein 0.0019 0.0006 0.0018
Schistosoma mansoni hypothetical protein 0.0136 0.0429 0.0428
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0027 0.0036 0.0696
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0011 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Brugia malayi beta-lactamase family protein 0.0035 0.0064 0.0354
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0027 0.0213
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0011 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0011 0.0009
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0064 0.0571
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0024 0.0046
Brugia malayi von Willebrand Factor 0.0027 0.0036 0.0191
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0001 0.0002
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0064 0.0341
Toxoplasma gondii ABC1 family protein 0.0035 0.0064 0.1263
Schistosoma mansoni twik family of potassium channels-related 0.0066 0.0176 0.0175
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0011 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0626 0.0624
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0064 0.0062
Schistosoma mansoni calcium-activated potassium channel 0.1463 0.5206 0.5205
Mycobacterium ulcerans lipase LipD 0.0035 0.0064 0.0621
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0166 0.0945
Plasmodium falciparum pyruvate kinase 0.0034 0.0061 0.1201
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0011 0.0043
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0027 0.0211
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0095 0.0094
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0027 0.0036 0.0696
Onchocerca volvulus 0.0066 0.0176 0.0938
Echinococcus granulosus metabotropic glutamate receptor 5 0.0053 0.013 0.0128
Leishmania major cathepsin L-like protease 0.0035 0.0064 0.0553
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0385 0.0384
Brugia malayi Cathepsin L-like precursor 0.0035 0.0064 0.0351
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0005 0.0015
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0086 0.077
Entamoeba histolytica hypothetical protein 0.0027 0.0036 0.1897
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0011 0.0009
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0166 0.0164
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0064 0.085
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0011 0.001
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0005 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.027 0.0909 0.526
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0011 0.0009
Leishmania major hypothetical protein, conserved 0.0213 0.0706 0.6576
Schistosoma mansoni pyruvate kinase 0.0034 0.0061 0.0059
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0064 0.0063
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0064 0.0567
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.0385 0.357
Schistosoma mansoni zinc finger protein 0.0019 0.0008 0.0006
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0064 0.0062
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.0379 0.0377
Toxoplasma gondii microneme protein MIC2 0.0027 0.0036 0.0696
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0576 0.3227
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0414 0.3851
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0005 0.0135
Echinococcus multilocularis thyroid hormone receptor alpha 0.0142 0.045 0.0449
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0017 0.013
Echinococcus multilocularis calcium activated potassium channel variant 0.0066 0.0176 0.0175
Schistosoma mansoni ferritin 0.0118 0.0364 0.0362
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.0166 0.0164
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0066 0.0176 0.0175
Loa Loa (eye worm) hypothetical protein 0.0142 0.045 0.0865
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0027 0.1399
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.003 0.025
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.061 0.342
Loa Loa (eye worm) hypothetical protein 0.0302 0.1024 0.1968
Echinococcus multilocularis tar DNA binding protein 0.0191 0.0626 0.0624
Brugia malayi Pre-SET motif family protein 0.0449 0.1554 0.9003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0011 0.0009
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0066 0.0176 0.1005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0011 0.0043
Brugia malayi TAR-binding protein 0.0191 0.0626 0.3614
Echinococcus granulosus tar DNA binding protein 0.0191 0.0626 0.0624
Brugia malayi Cathepsin L-like precursor 0.0023 0.0023 0.0112
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Echinococcus granulosus tumor protein p63 0.1038 0.3674 0.3673
Mycobacterium ulcerans ion transport protein 0.0066 0.0176 0.1797
Echinococcus granulosus twik family of potassium channels 0.0066 0.0176 0.0175
Brugia malayi MH2 domain containing protein 0.0034 0.0061 0.0334
Plasmodium vivax ataxin-2 like protein, putative 0.0155 0.0496 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.003 0.0045 0.0884
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.003 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.003 0.015
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.0385 0.7756
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0626 0.0624
Leishmania major GTP-binding protein, putative 0.0021 0.0015 0.0093
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0005 0.0004
Schistosoma mansoni intermediate filament proteins 0.0139 0.0438 0.0437
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0081
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0066 0.0176 0.1005
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0033 0.0627
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0024 0.1207
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0149 0.0475 0.4407
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0066 0.0176 0.1005
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0036 0.0191
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0064 0.085
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0005 0.0112
Plasmodium vivax potassium channel, putative 0.0066 0.0176 0.3532
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0036 0.0191
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0005 0.0018
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0005 0.0018
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0066 0.0176 0.0339
Trichomonas vaginalis ferritin, putative 0.0118 0.0364 0.2034
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0064 0.0063
Schistosoma mansoni ferritin 0.0118 0.0364 0.0362
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0027 0.0352
Trypanosoma cruzi cruzipain precursor, putative 0.0132 0.0414 0.3851
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0011 0.0021
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0085 0.1682
Trichomonas vaginalis esterase, putative 0.0035 0.0064 0.0343
Echinococcus granulosus importin subunit beta 1 0.0029 0.0042 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0045 0.0884
Echinococcus granulosus cathepsin l1 0.0035 0.0064 0.0062
Schistosoma mansoni hypothetical protein 0.0341 0.1167 0.1166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0011 0.0009
Brugia malayi RNA binding protein 0.0191 0.0626 0.3614
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0027 0.0237
Echinococcus granulosus potassium channel subfamily K 8 0.0066 0.0176 0.0175
Schistosoma mansoni DNA helicase recq5 0.003 0.0045 0.0044
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0066 0.0176 0.2372
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0005 0.0003
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0064 0.109
Loa Loa (eye worm) beta-lactamase 0.0035 0.0064 0.0123
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0043
Plasmodium vivax vivapain-2 0.0035 0.0064 0.1255
Brugia malayi RNA, U transporter 1 0.0081 0.0232 0.1327
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0036 0.0191
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0634 0.222 0.2219
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0036 0.0696
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0027 0.0213
Schistosoma mansoni ran 0.0021 0.0015 0.0013
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0576 0.3227
Mycobacterium tuberculosis Conserved protein 0.0035 0.0064 0.085
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0086 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0231 0.0229
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0162 0.016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Loa Loa (eye worm) hypothetical protein 0.011 0.0336 0.0645
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Brugia malayi Doublecortin family protein 0.002 0.0011 0.0046
Plasmodium falciparum potassium channel 0.0066 0.0176 0.3532
Schistosoma mansoni smad1 5 8 and 0.0034 0.0061 0.0059
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0027 0.0237
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0414 0.3851
Echinococcus granulosus FTZ F1 alpha 0.002 0.0011 0.0009
Onchocerca volvulus 0.0023 0.0023 0.0067
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0042 0.004
Schistosoma mansoni smad1 5 8 and 0.0034 0.0061 0.0059
Echinococcus multilocularis cysteine protease 0.0035 0.0064 0.0062
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0064 0.0341
Brugia malayi Immunoglobulin I-set domain containing protein 0.0027 0.0036 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0061 0.0542
Leishmania major mitochondrial DNA polymerase beta 0.0314 0.1071 1
Schistosoma mansoni twik family of potassium channels-related 0.0066 0.0176 0.0175
Echinococcus multilocularis GPCR, family 2 0.0063 0.0166 0.0164
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0043
Schistosoma mansoni glutaminase 0.0284 0.096 0.0958
Brugia malayi cathepsin L-like precursor 0.0023 0.0023 0.0112
Schistosoma mansoni biogenic amine (5HT) receptor 0.0142 0.045 0.0449
Echinococcus multilocularis potassium channel subfamily K 8 0.0066 0.0176 0.0175
Plasmodium vivax SET domain protein, putative 0.0064 0.0171 0.3415
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0909 0.5108
Giardia lamblia Sgs1 DNA helicase, putative 0.003 0.0045 0.1858
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0022 0.0108
Schistosoma mansoni metabotropic glutamate receptor 0.0036 0.0069 0.0067
Schistosoma mansoni pyruvate kinase 0.0034 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0064 0.0123
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0027 0.0036 0.0191
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.1038 0.1994
Entamoeba histolytica cysteine protease, putative 0.0035 0.0064 0.3494
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0036 0.0191
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0086 0.0084
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0011 0.0043
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0011 0.0043
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0061 0.0059
Schistosoma mansoni hypothetical protein 0.1463 0.5206 0.5205
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0011 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0064 0.0341
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0067 0.018 0.0346
Echinococcus granulosus small conductance calcium activated potassium 0.1463 0.5206 0.5205
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0064 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0027 0.0237
Echinococcus granulosus lamin 0.0139 0.0438 0.0437
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0176 0.1622
Brugia malayi beta-lactamase 0.0035 0.0064 0.0354
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0065 0.0064
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0018 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0011 0.0043
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0061 0.0117
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0171 0.0169
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0061 0.0285
Giardia lamblia GTOR 0.0018 0.0005 0.015
Mycobacterium ulcerans transmembrane cation transporter 0.0066 0.0176 0.1797
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0066 0.0176 0.0175
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.001
Loa Loa (eye worm) transcription factor SMAD2 0.0496 0.1726 0.3315
Onchocerca volvulus 0.0152 0.0486 0.2689
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0064 0.0062
Brugia malayi Calcitonin receptor-like protein seb-1 0.0199 0.0656 0.3792
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.0379 0.0377
Schistosoma mansoni amine GPCR 0.0365 0.1253 0.1251
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0027 0.0036 0.0696
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0061 0.0117
Loa Loa (eye worm) hypothetical protein 0.0035 0.0064 0.0123
Loa Loa (eye worm) hypothetical protein 0.0064 0.0171 0.0328
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.027 0.0909 0.1747
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0141 0.0139
Echinococcus granulosus potassium channel subfamily K 0.0066 0.0176 0.0175
Toxoplasma gondii LsmAD domain-containing protein 0.0155 0.0496 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0011 0.0043
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.0739 1
Echinococcus multilocularis snurportin 1 0.0305 0.1038 0.1037
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0083 0.0237 0.219
Echinococcus multilocularis small conductance calcium activated potassium 0.1463 0.5206 0.5205
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0066 0.0176 0.0976
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0027 0.1399
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0087
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Toxoplasma gondii ion channel protein 0.0066 0.0176 0.3532
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0005 0.001
Loa Loa (eye worm) glutaminase 2 0.0284 0.096 0.1843
Echinococcus granulosus snurportin 1 0.0305 0.1038 0.1037
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0066 0.0176 0.0976
Schistosoma mansoni hypothetical protein 0.0066 0.0176 0.0175
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0576 0.3227
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0086 0.0084
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0011 0.0021
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0061 0.0285
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0018 0.0017
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0066 0.0176 0.1005
Loa Loa (eye worm) hypothetical protein 0.0064 0.0171 0.0328
Schistosoma mansoni hypothetical protein 0.0069 0.0189 0.0187
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0005 0.0004
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0061 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0011 0.0009
Leishmania major cathepsin L-like protease 0.0035 0.0064 0.0553
Onchocerca volvulus 0.0035 0.0064 0.0303
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0064 0.0341
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0064 0.1255
Schistosoma mansoni hypothetical protein 0.0176 0.0574 0.0572
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0005 0.0071
Echinococcus granulosus metabotropic glutamate receptor 2 0.0036 0.0069 0.0067
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Onchocerca volvulus 0.0035 0.0064 0.03
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0086 0.0464
Onchocerca volvulus 0.0035 0.0064 0.03
Trichomonas vaginalis ran, putative 0.0021 0.0015 0.0065
Onchocerca volvulus 0.0035 0.0064 0.03
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0036 0.0191
Trypanosoma brucei telomerase reverse transcriptase 0.0083 0.0237 0.219
Schistosoma mansoni hypothetical protein 0.0176 0.0574 0.0572
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0053 0.013 0.0128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0142
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Schistosoma mansoni polycystin 1-related 0.002 0.0011 0.001
Echinococcus multilocularis tumor protein p63 0.1038 0.3674 0.3673
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.0706 0.6581
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0027 0.1399
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0064 0.0341
Echinococcus multilocularis pyruvate kinase 0.0034 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0027 0.0053
Loa Loa (eye worm) cysteine protease 0.0035 0.0064 0.0122
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0414 0.3851
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Entamoeba histolytica recQ family helicase, putative 0.0032 0.0056 0.3029
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0056 0.0477
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0066 0.0176 0.0339
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0385 0.3987
Brugia malayi Cathepsin L-like precursor 0.0035 0.0064 0.0351
Brugia malayi Cathepsin L-like precursor 0.0023 0.0023 0.0112
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0086 0.0477
Brugia malayi beta-lactamase family protein 0.0035 0.0064 0.0354
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0576 0.3227
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0064 0.0351
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0005 0.0003
Mycobacterium leprae Probable lipase LipE 0.0035 0.0064 0.109
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0066 0.0176 0.1005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Loa Loa (eye worm) hypothetical protein 0.1463 0.5206 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0005 0.0018
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0066 0.0176 0.1622
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0036 0.0191
Brugia malayi steroid hormone receptor 0.002 0.0011 0.0043
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0005 0.007
Onchocerca volvulus 0.0027 0.0036 0.0144
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.003 0.0045 0.0245
Plasmodium vivax telomerase reverse transcriptase, putative 0.0083 0.0237 0.4758
Echinococcus granulosus ferritin 0.0118 0.0364 0.0362
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0005 0.0004
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0191 0.0626 0.1202
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0066 0.0176 0.1005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0011 0.001
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0005 0.0003
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0027 0.0036 0.0185
Loa Loa (eye worm) hypothetical protein 0.0035 0.0064 0.0123
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0061 0.0059
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0011 0.0009
Brugia malayi Telomerase reverse transcriptase 0.022 0.0732 0.4232
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0385 0.0384
Mycobacterium ulcerans hypothetical protein 0.0025 0.0027 0.0235
Mycobacterium tuberculosis Conserved protein 0.0035 0.0064 0.085
Loa Loa (eye worm) fibroinase 0.0035 0.0064 0.0122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Echinococcus granulosus intermediate filament protein 0.0139 0.0438 0.0437
Trypanosoma brucei PAB1-binding protein , putative 0.0155 0.0496 0.462
Mycobacterium ulcerans hypothetical protein 0.0025 0.0027 0.0235
Loa Loa (eye worm) ATP-dependent DNA helicase 0.003 0.0045 0.0087
Echinococcus multilocularis musashi 0.0139 0.0438 0.0437
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0011 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0011 0.001
Echinococcus granulosus twik family of potassium channels 0.0066 0.0176 0.0175
Echinococcus multilocularis expressed protein 0.0118 0.0364 0.0362
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0909 0.5108
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0909 0.5108
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Schistosoma mansoni hypothetical protein 0.0063 0.0166 0.0164
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0023 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.0056 0.0491
Echinococcus multilocularis pyruvate kinase 0.0027 0.0035 0.0034
Echinococcus granulosus biogenic amine 5HT receptor 0.0142 0.045 0.0449
Echinococcus multilocularis geminin 0.0176 0.0574 0.0572
Echinococcus granulosus serine protein kinase ATM 0.0025 0.003 0.0028
Echinococcus granulosus pyruvate kinase 0.0034 0.0061 0.0059
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0027 0.0036 0.0696
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0231 0.0229
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0066 0.0176 0.0175
Echinococcus multilocularis potassium channel subfamily K 8 0.0066 0.0176 0.0175
Loa Loa (eye worm) ctsf protein 0.0035 0.0064 0.0122
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0118 0.0364 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0064 0.0341
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.0385 0.0384
Schistosoma mansoni rab6-interacting 0.002 0.0011 0.001
Loa Loa (eye worm) MH2 domain-containing protein 0.0496 0.1726 0.3315
Schistosoma mansoni hypothetical protein 0.0063 0.0166 0.0164
Brugia malayi latrophilin 2 splice variant baaae 0.0136 0.0429 0.2474
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0199 0.0656 0.1261
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0064 0.0341
Schistosoma mansoni twik family of potassium channels-related 0.0066 0.0176 0.0175
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0027 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0064 0.0343
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0064 0.0341
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0011 0.0043
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0005 0.007
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0011 0.0043
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0064 0.0123
Leishmania major importin beta-1 subunit, putative 0.0023 0.0022 0.0165
Toxoplasma gondii FATC domain-containing protein 0.0025 0.003 0.0571
Echinococcus granulosus pyruvate kinase 0.0034 0.0061 0.0059
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0086 0.0084
Mycobacterium tuberculosis Conserved protein 0.0035 0.0064 0.085
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0011 0.0009
Schistosoma mansoni hypothetical protein 0.0122 0.0379 0.0377
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0064 0.0062
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0011 0.0043
Schistosoma mansoni hypothetical protein 0.0063 0.0166 0.0164
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0166 0.0164
Brugia malayi MH2 domain containing protein 0.0496 0.1726 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0064 0.0341
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0064 0.03
Brugia malayi ecdysteroid receptor 0.002 0.0011 0.0043
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0086 0.3561
Mycobacterium ulcerans bacterioferritin BfrA 0.0118 0.0364 0.3762
Schistosoma mansoni apoferritin-2 0.0118 0.0364 0.0362
Onchocerca volvulus 0.0027 0.0036 0.0144
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0066 0.0176 0.1005
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Echinococcus multilocularis cathepsin L 0.0018 0.0003 0.0002
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0061 0.1201
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0005 0.0018
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0005 0.001
Loa Loa (eye worm) CUTiclin family member 0.0027 0.0036 0.0069
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0098 0.0889
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0027 0.0036 0.0696
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0095 0.0534
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0064 0.1255
Brugia malayi hypothetical protein 0.01 0.0299 0.1716
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0064 0.3494
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Mycobacterium tuberculosis Conserved hypothetical protein 0.0166 0.0535 0.7238
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0121 0.0373 0.3465
Loa Loa (eye worm) hypothetical protein 0.0023 0.0023 0.0043
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0015 0.0067
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0027 0.0237
Loa Loa (eye worm) hypothetical protein 0.0035 0.0064 0.0123
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0027 0.0036 0.0069
Loa Loa (eye worm) hypothetical protein 0.0139 0.0438 0.0842
Schistosoma mansoni twik family of potassium channels-related 0.0066 0.0176 0.0175
Schistosoma mansoni calcium-activated potassium channel 0.0066 0.0176 0.0175
Leishmania major telomerase reverse transcriptase, putative 0.0083 0.0237 0.2179
Echinococcus granulosus smad 0.0034 0.0061 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0023 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0064 0.0571
Onchocerca volvulus 0.0139 0.0438 0.2422
Schistosoma mansoni calcium-activated potassium channel 0.0066 0.0176 0.0175
Leishmania major hypothetical protein, conserved 0.0155 0.0496 0.4612
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0011 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0086 0.0464
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.003 0.025
Schistosoma mansoni DNA helicase recq1 0.003 0.0045 0.0044
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0061 0.0542
Loa Loa (eye worm) Smad1 0.0034 0.0061 0.0117
Loa Loa (eye worm) hypothetical protein 0.0081 0.0231 0.0443
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0069 0.0189 0.0187
Leishmania major cathepsin L-like protease 0.0132 0.0414 0.3842
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0061 0.0285
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0005 0.0018
Loa Loa (eye worm) glutaminase 0.0284 0.096 0.1843
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0095 0.0518
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0011 0.0009
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0118 0.0364 0.4916
Echinococcus multilocularis serotonin receptor 0.0142 0.045 0.0449
Brugia malayi intermediate filament protein 0.0139 0.0438 0.2527
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0064 0.0354
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0005 0.0004
Echinococcus multilocularis twik family of potassium channels 0.0066 0.0176 0.0175
Onchocerca volvulus 0.0139 0.0438 0.2422
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0003 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0064 0.0341
Schistosoma mansoni ap endonuclease 0.0018 0.0005 0.0003
Brugia malayi hypothetical protein 0.0066 0.0176 0.1005
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0576 0.3227
Brugia malayi Cathepsin L-like precursor 0.0035 0.0064 0.0351
Onchocerca volvulus 0.0027 0.0036 0.0144
Echinococcus granulosus muscleblind protein 0.0302 0.1024 0.1023
Schistosoma mansoni loxhd1 0.002 0.0011 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0027 0.0213
Echinococcus granulosus collagen alpha 1VII chain 0.0027 0.0036 0.0034
Schistosoma mansoni coup transcription factor 0.002 0.0011 0.0009
Onchocerca volvulus 0.0066 0.0176 0.0938
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0064 0.3494
Treponema pallidum bacterioferrin (TpF1) 0.0118 0.0364 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0066 0.0176 0.1005
Plasmodium falciparum importin beta, putative 0.0029 0.0042 0.0814
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0042 0.0814
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0011 0.0021
Trypanosoma cruzi PAB1-binding protein , putative 0.0155 0.0496 0.462
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Brugia malayi metabotropic glutamate receptor type 2 0.0021 0.0015 0.0066
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0064 0.085
Brugia malayi MH2 domain containing protein 0.0034 0.0061 0.0334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0066 0.0176 0.1005
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0061 0.0059
Loa Loa (eye worm) uncoordinated protein 58 0.0066 0.0176 0.0339
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0083 0.0237 0.219
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0086 0.475
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Brugia malayi hypothetical protein 0.0066 0.0176 0.1005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Loa Loa (eye worm) TWK-28 protein 0.0066 0.0176 0.0339
Schistosoma mansoni apoferritin-2 0.0118 0.0364 0.0362
Schistosoma mansoni thyroid hormone receptor 0.0142 0.045 0.0449
Trypanosoma brucei calcium-activated potassium channel, putative 0.0066 0.0176 0.1622
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0086 0.0757
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0066 0.0176 0.1005
Mycobacterium ulcerans bacterioferritin BfrB 0.0118 0.0364 0.3762
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0061 0.0326
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Loa Loa (eye worm) hypothetical protein 0.0034 0.0061 0.0117
Schistosoma mansoni smad 0.0034 0.0061 0.0059
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0314 0.1071 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0039 0.008 0.0443
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0385 0.3987
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0027 0.0235
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0129 0.0402 0.0772
Brugia malayi hypothetical protein 0.0027 0.0036 0.0191
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0064 0.0343
Leishmania major cathepsin L-like protease 0.0035 0.0064 0.0553
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0066 0.0176 0.1005
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0064 0.0621
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0061 0.0117
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.0385 0.5207
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0045 0.0884
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0314 0.1071 1
Schistosoma mansoni hypothetical protein 0.0027 0.0036 0.0034
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0005 0.0049
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0015 0.0108
Onchocerca volvulus 0.002 0.0011 0.0003
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0011 0.001
Loa Loa (eye worm) nuclear factor I 0.0019 0.0006 0.0012
Mycobacterium ulcerans hypothetical protein 0.0166 0.0535 0.5555
Schistosoma mansoni ferritin 0.0118 0.0364 0.0362
Trypanosoma cruzi ion transport protein, putative 0.0066 0.0176 0.1622
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0027 0.0225
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0036 0.0069 0.0067
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0027 0.0036 0.0034
Echinococcus granulosus RUN 0.002 0.0011 0.001
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0027 0.0036 0.0069
Schistosoma mansoni lamin 0.0139 0.0438 0.0437
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0005 0.0015
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0086 0.077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Brugia malayi Bromodomain containing protein 0.0037 0.0074 0.0408
Echinococcus granulosus ATP dependent DNA helicase Q5 0.003 0.0045 0.0044
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0027 0.0237
Brugia malayi nuclear hormone receptor 0.002 0.0011 0.0043
Trypanosoma cruzi PAB1-binding protein , putative 0.0155 0.0496 0.462
Plasmodium vivax importin-beta 2, putative 0.0029 0.0042 0.0814
Loa Loa (eye worm) glutamate receptor 0.0043 0.0094 0.0181
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0015 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0011 0.0043
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0036 0.0191
Brugia malayi Pre-SET motif family protein 0.0064 0.0171 0.0972
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0042 0.0362
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0098 0.0889
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0098 0.0889
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0061 0.0542
Brugia malayi nuclear receptor NHR-88 0.002 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0909 0.5108
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0064 0.085
Leishmania major potassium channel subunit-like protein 0.0066 0.0176 0.1609
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0086 0.0084
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0098 0.0889
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0027 0.0225
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0011 0.0009
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0066 0.0176 0.1005
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Loa Loa (eye worm) TWK-7 protein 0.0066 0.0176 0.0339
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.061 0.342
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Echinococcus granulosus cathepsin L 0.0018 0.0003 0.0002
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0015 0.0108
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0139 0.0438 0.0842
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Onchocerca volvulus 0.0066 0.0176 0.0938
Loa Loa (eye worm) hypothetical protein 0.0142 0.045 0.0865
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0303 0.103 0.5773
Brugia malayi Smad1 0.0034 0.0061 0.0334
Loa Loa (eye worm) hypothetical protein 0.0155 0.0496 0.0954
Schistosoma mansoni hypothetical protein 0.0027 0.0036 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0626 0.0624
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0036 0.1897
Schistosoma mansoni hypothetical protein 0.0305 0.1038 0.1037
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0909 0.5108
Echinococcus granulosus lamin dm0 0.0139 0.0438 0.0437
Brugia malayi Metabotropic glutamate receptor precursor. 0.0043 0.0094 0.0527
Plasmodium vivax thrombospondin-related anonymous protein 0.0027 0.0036 0.0696
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0022 0.018
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0005 0.0015
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0066 0.0176 0.0976
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0064 0.0343
Schistosoma mansoni ferritin light chain 0.0118 0.0364 0.0362
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0005 0.0018
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0064 0.085
Trypanosoma cruzi major cysteine proteinase, putative 0.0104 0.0313 0.2898
Leishmania major cathepsin L-like protease 0.0132 0.0414 0.3842
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0066 0.0176 0.0175
Echinococcus granulosus cathepsin l1 0.0023 0.0023 0.0021
Schistosoma mansoni twik family of potassium channels-related 0.0066 0.0176 0.0175
Echinococcus multilocularis cysteine protease 0.0035 0.0064 0.0062
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0064 0.0341
Loa Loa (eye worm) hypothetical protein 0.0042 0.0089 0.0171
Mycobacterium ulcerans hypothetical protein 0.0035 0.0064 0.0621
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0066 0.0176 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0064 0.0062
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0061 0.0336
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0086 0.0164
Onchocerca volvulus 0.0066 0.0176 0.0938
Schistosoma mansoni smad1 5 8 and 0.0034 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.001
Onchocerca volvulus 0.002 0.0011 0.0003
Brugia malayi von Willebrand factor type A domain containing protein 0.0027 0.0036 0.0191
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0166 0.0945
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0005 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0011 0.0021
Echinococcus multilocularis RUN 0.002 0.0011 0.001
Brugia malayi PHD-finger family protein 0.0024 0.0027 0.0135
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0064 0.0341
Echinococcus multilocularis zinc finger protein 0.0019 0.0008 0.0006
Brugia malayi hypothetical protein 0.002 0.0011 0.0046
Onchocerca volvulus 0.0035 0.0064 0.0303
Loa Loa (eye worm) hypothetical protein 0.0199 0.0656 0.1261
Loa Loa (eye worm) hypothetical protein 0.0035 0.0064 0.0123
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0061 0.0117
Echinococcus multilocularis lamin dm0 0.0139 0.0438 0.0437
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0011 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0027 0.0141
Loa Loa (eye worm) hypothetical protein 0.0024 0.0024 0.0046
Entamoeba histolytica hypothetical protein 0.0023 0.0022 0.111
Schistosoma mansoni serine-rich repeat protein 0.0341 0.1167 0.1166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Plasmodium vivax potassium channel, putative 0.0066 0.0176 0.3532
Loa Loa (eye worm) hypothetical protein 0.0035 0.0064 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.0023 0.0112
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0027 0.0237
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.0041 0.0039
Schistosoma mansoni tar DNA-binding protein 0.0191 0.0626 0.0624
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0011 0.0009
Giardia lamblia Pyruvate kinase 0.0034 0.0061 0.2525
Leishmania major cathepsin L-like protease 0.0132 0.0414 0.3842
Mycobacterium ulcerans beta-lactamase 0.0035 0.0064 0.0621
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0011 0.0009
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0042 0.0362
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0005 0.0018
Onchocerca volvulus 0.0066 0.0176 0.0938
Brugia malayi cytoplasmic intermediate filament protein 0.0074 0.0207 0.118
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0199 0.0656 0.3792
Loa Loa (eye worm) hypothetical protein 0.0063 0.0166 0.0319
Onchocerca volvulus 0.0027 0.0036 0.0144
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0027 0.0141
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0003 0.0002
Onchocerca volvulus 0.0066 0.0176 0.0938
Schistosoma mansoni ap endonuclease 0.0018 0.0005 0.0003
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0095 0.0518
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0005 0.0064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Onchocerca volvulus 0.0035 0.0064 0.03
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0011 0.0192
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0136 0.0429 0.0825
Toxoplasma gondii cathepsin CPL 0.0035 0.0064 0.1255
Onchocerca volvulus 0.0035 0.0064 0.03
Loa Loa (eye worm) hypothetical protein 0.0293 0.0992 0.1905
Echinococcus multilocularis potassium channel subfamily K 0.0066 0.0176 0.0175
Plasmodium vivax vivapain-1 0.0018 0.0003 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0909 0.5108
Schistosoma mansoni ran 0.0021 0.0015 0.0013
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0066 0.0176 0.0976
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0021
Onchocerca volvulus 0.0035 0.0064 0.03
Mycobacterium tuberculosis Conserved protein 0.0025 0.0027 0.035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Schistosoma mansoni importin beta-1 0.0029 0.0042 0.004
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0015 0.0265
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0005 0.0018
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0005 0.0011
Echinococcus multilocularis smad 0.0034 0.0061 0.0059
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0005 0.0003
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0067 0.018 0.0178
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0171 0.0169
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0066 0.0176 0.1622
Schistosoma mansoni bromodomain containing protein 0.0062 0.0161 0.016
Brugia malayi Zona pellucida-like domain containing protein 0.0027 0.0036 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0015 0.0556
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0061 0.0542
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0064 0.0571
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0064 0.0062
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0086 0.0084
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0011 0.0021
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0064 0.0343
Schistosoma mansoni calcium-activated potassium channel 0.1287 0.4572 0.4571
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0027 0.0237
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0061 0.0336
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Loa Loa (eye worm) intermediate filament protein 0.0139 0.0438 0.0842
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0066 0.0176 0.1622
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0064 0.0621
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0011 0.0009
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0011 0.0009
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0011 0.0009
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0066 0.0176 0.1005
Echinococcus multilocularis muscleblind protein 0.0302 0.1024 0.1023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Brugia malayi MH1 domain containing protein 0.0034 0.0061 0.0334
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0066 0.0176 0.1005
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0066 0.0176 0.0339
Trypanosoma cruzi ion transport protein, putative 0.0066 0.0176 0.1622
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0027 0.0135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0414 0.3851
Schistosoma mansoni ferritin 0.0118 0.0364 0.0362
Toxoplasma gondii hypothetical protein 0.0051 0.0122 0.2423
Echinococcus granulosus potassium channel subfamily K 8 0.0066 0.0176 0.0175
Loa Loa (eye worm) hypothetical protein 0.0027 0.0036 0.0069
Toxoplasma gondii exonuclease III APE 0.0018 0.0005 0.0064
Plasmodium falciparum ataxin-2 like protein, putative 0.0155 0.0496 1
Plasmodium falciparum telomerase reverse transcriptase 0.0083 0.0237 0.4758
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.0056 0.0296
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0065 0.0064
Loa Loa (eye worm) doublecortin family protein 0.002 0.0011 0.0021
Brugia malayi MH1 domain containing protein 0.0034 0.0061 0.0334
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0011 0.0043
Loa Loa (eye worm) hypothetical protein 0.0136 0.0429 0.0825
Schistosoma mansoni Smad4 0.0034 0.0061 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0011 0.0043
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0064 0.085
Giardia lamblia Telomerase catalytic subunit 0.0083 0.0237 1
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0027 0.0036 0.0696
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0005 0.0003
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0066 0.0176 0.0339
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0061 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0005 0.0011
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0005 0.0003
Trichomonas vaginalis set domain proteins, putative 0.0511 0.1777 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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