Detailed information for compound 1038177

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 236.138 | Formula: C10H15Cl2NO
  • H donors: 2 H acceptors: 1 LogP: 3.5 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: NCc1c(C)c(C)c(c(c1O)Cl)C.Cl
  • InChi: 1S/C10H14ClNO.ClH/c1-5-6(2)8(4-12)10(13)9(11)7(5)3;/h13H,4,12H2,1-3H3;1H
  • InChiKey: CTAWLUTYIGIHGY-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0029 0.0023 0.0019
Loa Loa (eye worm) agrin synaptic family protein 0.0106 0.013 0.1873
Loa Loa (eye worm) hypothetical protein 0.006 0.0066 0.0923
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.003 0.0026
Echinococcus granulosus bloom syndrome protein 0.0024 0.0015 0.0012
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0015 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0052 0.0055 0.0849
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0015 0.0228
Brugia malayi cysteinyl tRNA synthetase protein 1 0.0089 0.0106 0.1511
Loa Loa (eye worm) hypothetical protein 0.0074 0.0086 0.1216
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0036 0.1069
Mycobacterium tuberculosis Conserved protein 0.0224 0.0295 0.0332
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0045 0.0042
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.003 0.0026
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0008 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Trichomonas vaginalis esterase, putative 0.0224 0.0295 0.4566
Loa Loa (eye worm) hypothetical protein 0.0224 0.0295 0.4312
Brugia malayi Cathepsin L-like precursor 0.0052 0.0055 0.0764
Trypanosoma brucei hypothetical protein, conserved 0.0224 0.0295 1
Trichomonas vaginalis D-aminoacylase, putative 0.0224 0.0295 0.4566
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Trypanosoma cruzi cruzipain precursor, putative 0.0017 0.0006 0.0053
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.001 0.0007
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.0121 0.3994
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0026 0.077
Schistosoma mansoni intermediate filament proteins 0.0175 0.0226 0.0223
Brugia malayi cytoplasmic intermediate filament protein 0.0094 0.0113 0.1619
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0055 0.0849
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0032 0.0496
Echinococcus multilocularis beta LACTamase domain containing family member 0.0224 0.0295 0.0292
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0016 0.0005 0.0075
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0015 0.0228
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0009 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.001 0.0105
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.001 0.0007
Brugia malayi jmjC domain containing protein 0.0104 0.0128 0.1838
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0036 0.055
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0023 0.0623
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0023 0.0623
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0023 0.0009
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0049 0.0046
Toxoplasma gondii protease inhibitor PI2 0.0106 0.013 0.4329
Onchocerca volvulus 0.0099 0.0121 0.1825
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0066 0.0063
Trichomonas vaginalis abcb9, putative 0.0024 0.0015 0.0228
Brugia malayi prostaglandin transporter 0.0202 0.0264 0.3851
Echinococcus multilocularis ATP binding cassette sub family B 0.0023 0.0014 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0287
Echinococcus multilocularis cysteinyl tRNA synthetase 0.0089 0.0106 0.0102
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.0121 0.0116
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0055 0.0764
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0287
Schistosoma mansoni hypothetical protein 0.0102 0.0124 0.0121
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0036 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0184 0.0181
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.0055 0.0764
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0202 0.0264 0.0261
Mycobacterium ulcerans lipase LipD 0.0224 0.0295 0.0323
Loa Loa (eye worm) hypothetical protein 0.0224 0.0295 0.4312
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0094 0.0113 0.1619
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.003 0.0389
Brugia malayi Cathepsin L-like precursor 0.0052 0.0055 0.0764
Leishmania major cathepsin L-like protease 0.0052 0.0055 0.1734
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0048 0.0045
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0023 0.0291
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.003 0.0389
Loa Loa (eye worm) hypothetical protein 0.0089 0.0106 0.1511
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0015 0.0012
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0052 0.0055 0.0849
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0058 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0036 0.055
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0202 0.0264 0.0261
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0054 0.4676
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.001 0.0105
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0029 0.0023 0.0009
Onchocerca volvulus 0.0089 0.0106 0.1591
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0042
Trichomonas vaginalis penicillin-binding protein, putative 0.0224 0.0295 0.4566
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0045 0.0616
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0015 0.0228
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0029 0.0023 0.0009
Schistosoma mansoni microtubule-associated protein tau 0.7176 1 1
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0044 0.0041
Trypanosoma cruzi cysteine protease, putative 0.0027 0.002 0.0516
Loa Loa (eye worm) hypothetical protein 0.0202 0.0264 0.3851
Loa Loa (eye worm) hypothetical protein 0.0202 0.0264 0.3851
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0009 0.0006
Onchocerca volvulus Putative organic anion transporter 0.0202 0.0264 0.4053
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0052 0.0055 0.0052
Plasmodium vivax acyl-CoA synthetase, putative 0.0074 0.0086 0.2794
Brugia malayi nuclear receptor NHR-88 0.002 0.001 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.016 0.0205 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Brugia malayi Cathepsin L-like precursor 0.0052 0.0055 0.0764
Schistosoma mansoni lipoxygenase 0.0019 0.0009 0.0006
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0015 0.0228
Onchocerca volvulus 0.0052 0.0055 0.0804
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0065
Onchocerca volvulus 0.0202 0.0264 0.4053
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0049 0.1541
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0048 0.0045
Brugia malayi Cytochrome P450 family protein 0.0029 0.0023 0.0291
Plasmodium falciparum multidrug resistance protein 1 0.0024 0.0015 0.0589
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0099 0.0121 0.0116
Brugia malayi Pre-SET motif family protein 0.0418 0.0566 0.8309
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0055 0.1734
Echinococcus multilocularis musashi 0.0175 0.0226 0.0223
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0023 0.035
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0049 0.1541
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Echinococcus multilocularis cysteine protease 0.0052 0.0055 0.0052
Brugia malayi jmjC domain containing protein 0.0039 0.0036 0.0481
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0036 0.0033
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0015 0.0228
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.0121 0.3994
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.001 0.0007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.001 0.0007
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0099 0.0121 0.0116
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0049 0.1821
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0106 0.013 0.4329
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0066 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.001 0.0105
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0023 0.0299
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0027 0.002 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0049 0.0763
Schistosoma mansoni follistatin 0.0106 0.013 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0282
Echinococcus multilocularis tar DNA binding protein 0.0145 0.0184 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Entamoeba histolytica hypothetical protein 0.016 0.0205 1
Schistosoma mansoni hypothetical protein 0.0047 0.0048 0.0045
Leishmania major cathepsin L-like protease 0.0199 0.026 0.8792
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0032 0.0496
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Loa Loa (eye worm) hypothetical protein 0.0099 0.0121 0.1734
Echinococcus granulosus tumor protein p63 0.2484 0.3449 0.3447
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.008 0.0077
Leishmania major hypothetical protein, conserved 0.0052 0.0054 0.1708
Echinococcus multilocularis pol protein 0.0446 0.0605 0.0602
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.003 0.0026
Brugia malayi Bromodomain containing protein 0.0032 0.0026 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0005 0.007
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0023 0.0623
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0015 0.0228
Onchocerca volvulus 0.006 0.0066 0.0971
Onchocerca volvulus Putative organic anion transporter 0.0202 0.0264 0.4053
Onchocerca volvulus 0.0175 0.0226 0.3467
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0029 0.0023 0.0623
Trichomonas vaginalis cysteinyl-tRNA synthetase, putative 0.0089 0.0106 0.1632
Echinococcus multilocularis geminin 0.0182 0.0235 0.0232
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0017 0.0006 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0049 0.0763
Echinococcus granulosus geminin 0.0182 0.0235 0.0232
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.001 0.0105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0055 0.0849
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.0121 0.0116
Schistosoma mansoni hypothetical protein 0.0047 0.0048 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0015 0.0231
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.001 0.0007
Loa Loa (eye worm) oxidoreductase 0.0029 0.0023 0.0287
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0229 0.0302 0.441
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.001 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Loa Loa (eye worm) hypothetical protein 0.0099 0.0121 0.1734
Mycobacterium leprae conserved hypothetical protein 0.0224 0.0295 0.0323
Loa Loa (eye worm) hypothetical protein 0.0099 0.0121 0.1734
Loa Loa (eye worm) hypothetical protein 0.0119 0.0148 0.2142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0055 0.0849
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0165
Brugia malayi TAR-binding protein 0.0145 0.0184 0.2675
Echinococcus granulosus tar DNA binding protein 0.0145 0.0184 0.0181
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.002 0.0516
Brugia malayi secreted modular calcium-binding protein 1 0.0106 0.013 0.1873
Loa Loa (eye worm) hypothetical protein 0.0224 0.0295 0.4312
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0036 0.055
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0287
Onchocerca volvulus 0.0202 0.0264 0.4053
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0054 0.1723
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0032 0.0496
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0023 0.0623
Loa Loa (eye worm) hypothetical protein 0.0052 0.0055 0.0764
Brugia malayi Cathepsin L-like precursor 0.0052 0.0055 0.0764
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0015 0.0228
Brugia malayi sodium-independent organic anion transporter family protein 0.0202 0.0264 0.3851
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0054 0.1708
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.001 0.0105
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0224 0.0295 0.0292
Trypanosoma brucei cysteinyl-tRNA synthetase, putative 0.0089 0.0106 0.3475
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0015 0.0228
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0015 0.0012
Echinococcus granulosus beta LACTamase domain containing family member 0.0224 0.0295 0.0292
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0066 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0032 0.0496
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.001 0.0105
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0202 0.0264 0.3851
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0145 0.0184 0.2675
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0005 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0055 0.0849
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0089 0.0106 0.0102
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0045 0.0616
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0049 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.001 0.0007
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0023 0.0623
Onchocerca volvulus 0.0106 0.013 0.1972
Loa Loa (eye worm) MH2 domain-containing protein 0.05 0.0681 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.008 0.0077
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0105
Schistosoma mansoni thyroid hormone receptor 0.0149 0.019 0.0187
Trypanosoma cruzi cysteine peptidase, putative 0.0199 0.026 0.8792
Brugia malayi hypothetical protein 0.016 0.0205 0.2975
Schistosoma mansoni hypothetical protein 0.0182 0.0235 0.0232
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0009 0.0006
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.001 0.0007
Loa Loa (eye worm) cysteine protease 0.0052 0.0055 0.0764
Loa Loa (eye worm) intermediate filament protein 0.0175 0.0226 0.3294
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0184 0.0181
Schistosoma mansoni rab6-interacting 0.0019 0.0009 0.0006
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.001 0.0007
Brugia malayi MH1 domain containing protein 0.0019 0.0008 0.0075
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0015 0.0174
Loa Loa (eye worm) hypothetical protein 0.0106 0.013 0.1873
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0026 0.077
Echinococcus granulosus multidrug resistance protein 1 0.0016 0.0005 0.0002
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0015 0.0228
Loa Loa (eye worm) RNA binding protein 0.0145 0.0184 0.2675
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0036 0.1069
Echinococcus granulosus FTZ F1 alpha 0.002 0.001 0.0007
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0029 0.0023 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0105
Mycobacterium ulcerans beta-lactamase 0.0224 0.0295 0.0323
Leishmania major cysteinyl-tRNA synthetase, putative 0.0089 0.0106 0.3475
Brugia malayi sodium-independent organic anion transporter family protein 0.0202 0.0264 0.3851
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0084 0.01 0.0097
Schistosoma mansoni smad1 5 8 and 0.0034 0.003 0.0026
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0084 0.01 0.0097
Entamoeba histolytica hypothetical protein 0.016 0.0205 1
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0024 0.0015 0.0171
Entamoeba histolytica acyl-CoA synthetase, putative 0.0099 0.0121 0.5575
Brugia malayi Cathepsin L-like precursor 0.0035 0.0031 0.0408
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0015 0.0012
Schistosoma mansoni cathepsin F (C01 family) 0.0052 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0105
Mycobacterium leprae Probable cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.6074 0.8462 1
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.6074 0.8462 1
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0184 0.0181
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0005 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0224 0.0295 0.4566
Brugia malayi AMP-binding enzyme family protein 0.0099 0.0121 0.1734
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0023 0.0287
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0049 0.1541
Trichomonas vaginalis D-aminoacylase, putative 0.0224 0.0295 0.4566
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0017 0.0003
Echinococcus granulosus RUN 0.0019 0.0009 0.0006
Trypanosoma cruzi cysteine proteinase, putative 0.0027 0.002 0.0516
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0015 0.0228
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0026 0.0343
Loa Loa (eye worm) hypothetical protein 0.0175 0.0226 0.3294
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0023 0.0623
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0224 0.0295 0.0292
Entamoeba histolytica hypothetical protein 0.016 0.0205 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0049 0.1541
Onchocerca volvulus Cathepsin L homolog 0.0052 0.0055 0.0804
Onchocerca volvulus 0.0029 0.0023 0.0302
Loa Loa (eye worm) ctsf protein 0.0052 0.0055 0.0764
Echinococcus granulosus cathepsin L cysteine protease 0.0027 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0202 0.0264 0.3851
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0105
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0184 0.0181
Echinococcus multilocularis follistatin 0.0106 0.013 0.0127
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0202 0.0264 0.0261
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0049 0.1541
Loa Loa (eye worm) hypothetical protein 0.0202 0.0264 0.3851
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.001 0.0007
Echinococcus granulosus lamin 0.0175 0.0226 0.0223
Brugia malayi hypothetical protein 0.0202 0.0264 0.3851
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.008 0.0077
Echinococcus multilocularis smad 0.0034 0.003 0.0026
Plasmodium falciparum phd finger protein, putative 0.0032 0.0026 0.18
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0027 0.002 0.0016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.001 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0005 0.007
Onchocerca volvulus 0.0052 0.0055 0.0804
Brugia malayi AMP-binding enzyme family protein 0.0099 0.0121 0.1734
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0023 0.0287
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0048 0.0658
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0014 0.0011
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0098 0.0095
Schistosoma mansoni lamin 0.0175 0.0226 0.0223
Schistosoma mansoni hypothetical protein 0.0182 0.0235 0.0232
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0048 0.0658
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0011 0.0196
Loa Loa (eye worm) hypothetical protein 0.0055 0.0058 0.0813
Plasmodium falciparum cysteine--tRNA ligase 0.0089 0.0106 1
Onchocerca volvulus 0.0052 0.0055 0.0804
Echinococcus granulosus leucyl tRNA synthetase 0.0089 0.0106 0.0102
Schistosoma mansoni organic anion transporter 0.0202 0.0264 0.0261
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0015 0.0012
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0049 0.1821
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0175 0.0226 0.3294
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.001 0.0111
Schistosoma mansoni hypothetical protein 0.016 0.0205 0.0202
Brugia malayi Smad1 0.0034 0.003 0.0389
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0036 0.0033
Schistosoma mansoni coup transcription factor 0.002 0.001 0.0007
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0023 0.0623
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0015 0.0228
Loa Loa (eye worm) hypothetical protein 0.0074 0.0086 0.1216
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Schistosoma mansoni lipoxygenase 0.0054 0.0058 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.001 0.0105
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.0086 0.0075
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0089 0.0106 0.3475
Schistosoma mansoni multidrug resistance protein 0.0024 0.0015 0.0012
Loa Loa (eye worm) multidrug resistance protein 3 0.0024 0.0015 0.0171
Brugia malayi intermediate filament protein 0.0175 0.0226 0.3294
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.001 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0005 0.007
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0032 0.0963
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0015 0.0012
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0015 0.0228
Onchocerca volvulus 0.0019 0.0009 0.0091
Leishmania major cathepsin L-like protease 0.0199 0.026 0.8792
Loa Loa (eye worm) hypothetical protein 0.0224 0.0295 0.4312
Loa Loa (eye worm) hypothetical protein 0.0081 0.0095 0.1361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0032 0.0496
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.019 0.2758
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0023 0.0631
Brugia malayi MH1 domain containing protein 0.0034 0.003 0.0389
Loa Loa (eye worm) hypothetical protein 0.0074 0.0086 0.1216
Mycobacterium ulcerans esterase/lipase LipP 0.0224 0.0295 0.0323
Echinococcus multilocularis GPCR, family 2 0.0047 0.0048 0.0045
Plasmodium vivax SET domain protein, putative 0.006 0.0066 0.2111
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0023 0.0287
Onchocerca volvulus 0.0175 0.0226 0.3467
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0052 0.0055 0.0052
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0045 0.0042
Toxoplasma gondii propionate-CoA ligase 0.0029 0.0023 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0022 0.0337
Schistosoma mansoni acetyl-CoA synthetase 0.0029 0.0023 0.0019
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0029 0.0023 0.0287
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0029 0.0023 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0026 0.0397
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0015 0.0228
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0048 0.0045
Mycobacterium ulcerans hypothetical protein 0.0224 0.0295 0.0323
Mycobacterium ulcerans hypothetical protein 0.0099 0.0121 0.0116
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0015 0.0012
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.001 0.0007
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0106 0.013 0.1873
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0048 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.001 0.0105
Brugia malayi beta-lactamase family protein 0.0224 0.0295 0.4312
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0418 0.0566 0.8309
Loa Loa (eye worm) hypothetical protein 0.0224 0.0295 0.4312
Plasmodium falciparum cysteine proteinase falcipain 1 0.0027 0.002 0.1085
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0224 0.0295 0.0332
Loa Loa (eye worm) hypothetical protein 0.0032 0.0026 0.0343
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0054 0.1715
Schistosoma mansoni cathepsin F (C01 family) 0.0052 0.0055 0.0052
Onchocerca volvulus Putative organic anion transporter 0.0202 0.0264 0.4053
Treponema pallidum cysteinyl-tRNA synthetase 0.0089 0.0106 0.5
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0024 0.0015 0.0369
Brugia malayi MH2 domain containing protein 0.0034 0.003 0.0389
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0022 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.001 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0009 0.0087
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.001 0.0007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0023 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0199 0.026 0.8792
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.001 0.0007
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0106 0.013 0.1873
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0005 0.0001
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0104 0.0128 0.0125
Loa Loa (eye worm) hypothetical protein 0.0149 0.019 0.2758
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.002 0.0241
Echinococcus multilocularis tumor protein p63 0.2484 0.3449 0.3447
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.002 0.0241
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.0015 0.0369
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0036 0.055
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0105
Loa Loa (eye worm) hypothetical protein 0.0084 0.01 0.1427
Loa Loa (eye worm) hypothetical protein 0.0106 0.013 0.1873
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0106 0.013 0.1873
Brugia malayi multidrug resistance protein 3 0.0024 0.0015 0.0171
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.001 0.0007
Brugia malayi MH2 domain containing protein 0.05 0.0681 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0042
Echinococcus granulosus Smad4 0.0034 0.003 0.0026
Brugia malayi Cathepsin L-like precursor 0.0017 0.0006 0.0042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.001 0.0007
Plasmodium vivax vivapain-1 0.0027 0.002 0.0525
Onchocerca volvulus 0.0029 0.0023 0.0302
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0049 0.0681
Schistosoma mansoni cellular tumor antigen P53 0.0364 0.0489 0.0486
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0015 0.0228
Echinococcus multilocularis cathepsin L 0.0027 0.002 0.0016
Echinococcus granulosus smad 0.0034 0.003 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0015 0.0012
Loa Loa (eye worm) nuclear factor I 0.0019 0.0008 0.0075
Brugia malayi RNA recognition motif domain containing protein 0.0145 0.0184 0.2675
Mycobacterium tuberculosis Conserved protein 0.0224 0.0295 0.0332
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0055 0.0849
Schistosoma mansoni smad1 5 8 and 0.0034 0.003 0.0026
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0224 0.0295 0.0332
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0015 0.0012
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0015 0.0228
Onchocerca volvulus 0.0052 0.0055 0.0804
Brugia malayi hypothetical protein 0.0019 0.0009 0.0087
Echinococcus multilocularis cathepsin L cysteine protease 0.0052 0.0055 0.0052
Schistosoma mansoni thyroid hormone receptor 0.0149 0.019 0.0187
Onchocerca volvulus 0.0202 0.0264 0.4053
Mycobacterium tuberculosis Probable hydrolase 0.0224 0.0295 0.0332
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.001 0.0105
Brugia malayi nuclear hormone receptor 0.002 0.001 0.0105
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0026 0.0023
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0074 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0287
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0074 0.1043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0283
Schistosoma mansoni hypothetical protein 0.0023 0.0014 0.0011
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0005 0.0001
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.6074 0.8462 1
Echinococcus granulosus cathepsin l1 0.0035 0.0031 0.0028
Leishmania major hypothetical protein, conserved 0.0224 0.0295 1
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0054 0.1708
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.016 0.0205 0.0202
Echinococcus multilocularis multidrug resistance protein 1 0.0016 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0202 0.0264 0.3851
Onchocerca volvulus 0.0476 0.0647 1
Leishmania major cytochrome p450-like protein 0.0029 0.0023 0.0631
Loa Loa (eye worm) hypothetical protein 0.0364 0.0489 0.7178
Brugia malayi cathepsin L-like precursor 0.0035 0.0031 0.0408
Trichomonas vaginalis abcb9, putative 0.0024 0.0015 0.0228
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0054 0.4676
Brugia malayi hypothetical protein 0.0033 0.0029 0.0375
Onchocerca volvulus Cathepsin F homolog 0.0052 0.0055 0.0804
Brugia malayi ecdysteroid receptor 0.002 0.001 0.0105
Loa Loa (eye worm) hypothetical protein 0.0029 0.0023 0.0287
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0023 0.0623
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0052 0.0055 0.4754
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.0295 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.001 0.0105
Onchocerca volvulus 0.0035 0.0031 0.0429
Brugia malayi MH2 domain containing protein 0.0034 0.003 0.0389
Schistosoma mansoni nuclear hormone receptor 0.002 0.001 0.0007
Brugia malayi SPARC precursor 0.0106 0.013 0.1873
Schistosoma mansoni lamin 0.0175 0.0226 0.0223
Schistosoma mansoni hypothetical protein 0.0047 0.0048 0.0045
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.002 0.0252
Echinococcus multilocularis pol protein 0.0446 0.0605 0.0602
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Loa Loa (eye worm) TAR-binding protein 0.0145 0.0184 0.2675
Brugia malayi MH1 domain containing protein 0.0034 0.003 0.0389
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0024 0.0015 0.0351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0036 0.055
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1434 0.1984 0.2331
Plasmodium vivax cysteine--tRNA ligase, putative 0.0089 0.0106 0.3481
Loa Loa (eye worm) RecQ helicase 0.0024 0.0015 0.0174
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0029 0.0023 0.0019
Echinococcus multilocularis cathepsin L cysteine protease 0.0052 0.0055 0.0052
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0023 0.0631
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.001 0.0105
Loa Loa (eye worm) hypothetical protein 0.0172 0.0222 0.3228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0039 0.061
Leishmania major cathepsin L-like protease 0.0052 0.0055 0.1734
Trichomonas vaginalis abcb9, putative 0.0024 0.0015 0.0228
Onchocerca volvulus Cathepsin L homolog 0.0052 0.0055 0.0804
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0049 0.0681
Leishmania major cathepsin L-like protease 0.0052 0.0055 0.1734
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Trypanosoma cruzi MFS transporter, putative 0.0202 0.0264 0.8925
Trypanosoma brucei cytochrome P450, putative 0.0029 0.0023 0.0631
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0023 0.0287
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0015 0.0228
Brugia malayi Cytochrome P450 family protein 0.003 0.0023 0.0299
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0052 0.0055 0.0764
Echinococcus granulosus cysteine protease 0.0027 0.002 0.0016
Loa Loa (eye worm) CYP4Cod1 0.0029 0.0023 0.0291
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0066 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0184 0.0181
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.002 0.0252
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0026 0.0023
Brugia malayi Cathepsin L-like cysteine proteinase 0.0035 0.0031 0.0408
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.003 0.0026
Echinococcus multilocularis FTZ F1 alpha 0.002 0.001 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0045 0.0042
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0124 0.1786
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0015 0.0228
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.001 0.0105
Loa Loa (eye worm) hypothetical protein 0.0102 0.0124 0.1786
Echinococcus multilocularis pol protein 0.0446 0.0605 0.0602
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0006 0.0053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0055 0.0849
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0224 0.0295 0.4312
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0074 0.0086 0.7799
Brugia malayi follicle stimulating hormone receptor 0.0229 0.0302 0.441
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.001 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0224 0.0295 0.4566
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0015 0.0228
Echinococcus granulosus lamin dm0 0.0175 0.0226 0.0223
Echinococcus granulosus cysteinyl tRNA synthetase 0.0089 0.0106 0.0102
Brugia malayi MH1 domain containing protein 0.0019 0.0008 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.0015 0.0228
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0089 0.0106 0.3475
Schistosoma mansoni smad1 5 8 and 0.0034 0.003 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.0121 0.0116
Trichomonas vaginalis taga, putative 0.0024 0.0015 0.0228
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0224 0.0295 0.4312
Loa Loa (eye worm) Smad1 0.0034 0.003 0.0389
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0029 0.0023 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0199 0.026 0.8792
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0015 0.0228
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0055 0.0849
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0009 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0045 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Trypanosoma cruzi cysteine proteinase, putative 0.0027 0.002 0.0516
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.002 0.0252
Onchocerca volvulus 0.0052 0.0055 0.0804
Schistosoma mansoni hypothetical protein 0.0032 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0202 0.0264 0.3851
Echinococcus granulosus agrin 0.0106 0.013 0.0127
Onchocerca volvulus 0.0029 0.0023 0.0302
Trichomonas vaginalis set domain proteins, putative 0.0476 0.0647 1
Toxoplasma gondii cathepsin CPL 0.0052 0.0055 0.1749
Entamoeba histolytica cysteine protease, putative 0.0052 0.0055 0.2116
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0099 0.0121 0.0125
Schistosoma mansoni multidrug resistance protein 0.0024 0.0015 0.0012
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0009 0.0165
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.001 0.0105
Brugia malayi Cathepsin L-like precursor 0.0035 0.0031 0.0408
Brugia malayi Pre-SET motif family protein 0.006 0.0066 0.0923
Loa Loa (eye worm) hypothetical protein 0.0202 0.0264 0.3851
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.001 0.0007
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.002 0.0516
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.002 0.0516
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.0015 0.0228
Onchocerca volvulus 0.0224 0.0295 0.4539
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.001 0.0007
Loa Loa (eye worm) transcription factor SMAD2 0.05 0.0681 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.0015 0.0228
Brugia malayi sodium-independent organic anion transporter family protein 0.0202 0.0264 0.3851
Schistosoma mansoni hypothetical protein 0.0019 0.0009 0.0006
Echinococcus multilocularis agrin 0.0106 0.013 0.0127
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0015 0.0012
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0074 0.0086 0.1216
Onchocerca volvulus 0.0364 0.0489 0.7555
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.002 0.0302
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0224 0.0295 0.0332
Brugia malayi beta-lactamase 0.0224 0.0295 0.4312
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0049 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0283
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0029 0.0023 0.0009
Plasmodium vivax vivapain-3 0.0027 0.002 0.0525
Onchocerca volvulus 0.0019 0.0009 0.0091
Trypanosoma cruzi cruzipain precursor, putative 0.0199 0.026 0.8792
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0105
Schistosoma mansoni multidrug resistance protein 0.0024 0.0015 0.0012
Onchocerca volvulus 0.0029 0.0023 0.0302
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0015 0.0012
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.0121 0.3994
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0055 0.0849
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0026 0.0762
Plasmodium vivax vivapain-2 0.0052 0.0055 0.1742
Chlamydia trachomatis cysteine--tRNA ligase 0.0089 0.0106 1
Brugia malayi Steroid receptor seven-up type 2 0.002 0.001 0.0105
Schistosoma mansoni Smad4 0.0034 0.003 0.0026
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0104 0.0128 0.0125
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0171
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.001 0.0105
Onchocerca volvulus 0.0202 0.0264 0.4053
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0066 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0005 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0026 0.0023
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Plasmodium vivax hypothetical protein, conserved 0.0224 0.0295 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0106 0.013 0.4329
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0408
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0099 0.0121 0.0116
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0029 0.0023 0.0416
Loa Loa (eye worm) hypothetical protein 0.0047 0.0048 0.0658
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0031 0.0476
Loa Loa (eye worm) hypothetical protein 0.0081 0.0095 0.1361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0005 0.007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0042
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.001 0.0007
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0029 0.0023 0.1408
Loa Loa (eye worm) hypothetical protein 0.0074 0.0086 0.1216
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0408
Echinococcus granulosus GPCR family 2 0.0047 0.0048 0.0045
Echinococcus multilocularis microtubule associated protein 2 0.7176 1 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0027 0.002 0.0016
Brugia malayi hypothetical protein 0.0019 0.0009 0.0087
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0106 0.013 0.1873
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0045 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0032 0.0496
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0048 0.0658
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0066 0.0063
Onchocerca volvulus 0.0224 0.0295 0.4539
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.0121 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0022 0.0343
Entamoeba histolytica cysteinyl-tRNA synthetase, putative 0.0089 0.0106 0.4781
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.002 0.0252
Echinococcus multilocularis thyroid hormone receptor alpha 0.0149 0.019 0.0187
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0055 0.0849
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.0121 0.0116
Brugia malayi cathepsin F-like cysteine proteinase 0.0017 0.0006 0.0042
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0063 0.0059
Loa Loa (eye worm) cysteinyl tRNA synthetase 1 0.0089 0.0106 0.1511
Schistosoma mansoni smad 0.0034 0.003 0.0026
Echinococcus granulosus peregrin 0.0032 0.0026 0.0023
Entamoeba histolytica cysteine proteinase 2 0.0027 0.002 0.0252
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0105
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Onchocerca volvulus 0.0024 0.0015 0.0179
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0029 0.0023 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.008 0.0077
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.001 0.0105
Leishmania major cathepsin L-like protease 0.0199 0.026 0.8792
Plasmodium vivax unspecified product 0.0027 0.002 0.0525
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0054 0.1708
Leishmania major cysteine peptidase A (CPA) 0.0052 0.0055 0.1734
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0029 0.0023 0.064
Brugia malayi ABC transporter family protein 0.0024 0.0015 0.0171
Trichomonas vaginalis ABC transporter, putative 0.0024 0.0015 0.0228
Echinococcus multilocularis lamin dm0 0.0175 0.0226 0.0223
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0066 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0031 0.0476
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0023 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.001 0.0105
Schistosoma mansoni cathepsin s 0.0017 0.0006 0.0003
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.0015 0.0012
Schistosoma mansoni hypothetical protein 0.0129 0.0162 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0032 0.0496
Entamoeba histolytica acyl-CoA synthetase, putative 0.0099 0.0121 0.5575
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.003 0.0026
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0005 0.0001
Onchocerca volvulus Bile acid receptor homolog 0.002 0.001 0.0111
Onchocerca volvulus 0.0052 0.0055 0.0804
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0006 0.0042
Schistosoma mansoni polycystin 1-related 0.0019 0.0009 0.0006
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.0015 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0027 0.042
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.001 0.0186
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0087
Brugia malayi PHD-finger family protein 0.0032 0.0026 0.0343
Onchocerca volvulus 0.0224 0.0295 0.4539
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0105
Mycobacterium leprae Probable lipase LipE 0.0224 0.0295 0.0323
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0031 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0022 0.0337
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0045 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0283
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Leishmania major cathepsin L-like protease 0.0052 0.0055 0.1734
Wolbachia endosymbiont of Brugia malayi cysteinyl-tRNA synthetase 0.0089 0.0106 0.5
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0031 0.0845
Onchocerca volvulus 0.0052 0.0055 0.0804
Loa Loa (eye worm) hypothetical protein 0.0052 0.0054 0.0753
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0283
Brugia malayi Cytochrome P450 family protein 0.0029 0.0023 0.0291
Brugia malayi Doublecortin family protein 0.0019 0.0009 0.0087
Entamoeba histolytica acyl-coA synthetase, putative 0.0099 0.0121 0.5575
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.001 0.0105
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0106 0.013 0.4329
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.001 0.0007
Brugia malayi beta-lactamase family protein 0.0224 0.0295 0.4312
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0036 0.0033
Brugia malayi Cathepsin L-like precursor 0.0052 0.0055 0.0764
Brugia malayi RNA binding protein 0.0145 0.0184 0.2675
Loa Loa (eye worm) hypothetical protein 0.0106 0.013 0.1873
Echinococcus multilocularis Smad4 0.0034 0.003 0.0026
Schistosoma mansoni agrin 0.0106 0.013 0.0127
Plasmodium vivax multidrug resistance protein 1, putative 0.0024 0.0015 0.036
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0015 0.0228
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0009 0.0006
Schistosoma mansoni organic anion transporter 0.0202 0.0264 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0282
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0058 0.0055
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.0015 0.0012
Brugia malayi steroid hormone receptor 0.002 0.001 0.0105
Entamoeba histolytica hypothetical protein 0.016 0.0205 1
Echinococcus multilocularis RUN 0.0019 0.0009 0.0006
Leishmania major p-glycoprotein 0.0024 0.0015 0.0351
Plasmodium falciparum cysteine proteinase falcipain 3 0.0052 0.0055 0.4754
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0044 0.0041
Echinococcus granulosus intermediate filament protein 0.0175 0.0226 0.0223
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.001 0.0007
Onchocerca volvulus Alhambra homolog 0.0032 0.0026 0.0361
Plasmodium falciparum acyl-CoA synthetase 0.0074 0.0086 0.7929
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0023 0.0291
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.001 0.0007
Leishmania major cathepsin L-like protease 0.0052 0.0055 0.1734
Mycobacterium tuberculosis Probable lipase LipE 0.0224 0.0295 0.0332
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0055 0.2116
Giardia lamblia GTOR 0.0048 0.0049 0.2895
Mycobacterium tuberculosis Conserved protein 0.0224 0.0295 0.0332
Plasmodium falciparum cysteine--tRNA ligase 0.0089 0.0106 1
Loa Loa (eye worm) hypothetical protein 0.0224 0.0295 0.4312
Echinococcus granulosus Solute carrier organic anion transporter family 0.0202 0.0264 0.0261
Echinococcus multilocularis pol protein 0.0446 0.0605 0.0602
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0023 0.0014 0.0011
Echinococcus granulosus cathepsin L cysteine proteinase 0.0052 0.0055 0.0052
Schistosoma mansoni rab6-interacting 0.0019 0.0009 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.0295 1
Toxoplasma gondii cysteine-tRNA synthetase (CysRS) 0.0089 0.0106 0.3487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Onchocerca volvulus 0.002 0.001 0.0111
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0036 0.1069
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.001 0.0007
Echinococcus granulosus follistatin 0.0106 0.013 0.0127
Toxoplasma gondii transporter, major facilitator family protein 0.0202 0.0264 0.8927
Loa Loa (eye worm) hypothetical protein 0.0106 0.013 0.1873
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0023 0.035
Loa Loa (eye worm) steroid hormone receptor 0.002 0.001 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.001 0.0105
Loa Loa (eye worm) beta-lactamase 0.0224 0.0295 0.4312
Mycobacterium tuberculosis Probable esterase LipL 0.0224 0.0295 0.0332
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0029 0.0023 0.0009
Brugia malayi hypothetical protein 0.0202 0.0264 0.3851
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.019 0.2758
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0099 0.0121 0.0116
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0224 0.0295 0.0323
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0018 0.0282
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0023 0.0009
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0036 0.0481
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0089 0.0106 0.0098
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0045 0.0042
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0014 0.0011
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0052 0.0055 0.4754
Echinococcus granulosus cathepsin l1 0.0052 0.0055 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0087
Echinococcus granulosus multidrug resistance protein 1 0.0016 0.0005 0.0002
Schistosoma mansoni transcription factor LCR-F1 0.016 0.0205 0.0202
Plasmodium vivax vivapain-2 0.0052 0.0055 0.1742
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0106 0.013 0.4329
Brugia malayi AMP-binding enzyme family protein 0.0099 0.0121 0.1734
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0027 0.002 0.0516
Entamoeba histolytica cysteine proteinase 1, putative 0.0027 0.002 0.0252
Plasmodium vivax acetyl-CoA synthetase, putative 0.0029 0.0023 0.0632
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0106 0.013 0.1873
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.0015 0.0228
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.001 0.0105
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0089 0.0106 0.0102
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Echinococcus multilocularis expressed protein 0.0106 0.013 0.0127
Onchocerca volvulus 0.0202 0.0264 0.4053
Schistosoma mansoni hypothetical protein 0.0047 0.0048 0.0045
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0129 0.0162 0.0159
Echinococcus granulosus cathepsin l cysteine peptidase 0.0052 0.0055 0.0052
Brugia malayi Intermediate filament tail domain containing protein 0.0175 0.0226 0.3294
Entamoeba histolytica cysteine protease, putative 0.0027 0.002 0.0252
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.019 0.2758
Schistosoma mansoni loxhd1 0.0019 0.0009 0.0006
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0129 0.0162 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.001 0.0105
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0055 0.2116
Echinococcus multilocularis peregrin 0.0032 0.0026 0.0023
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0049 0.1541
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0099 0.0121 0.0125
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0014 0.0319
Brugia malayi Cathepsin L-like precursor 0.0052 0.0055 0.0764
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0022 0.0343
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0015 0.0231
Trypanosoma cruzi cysteine peptidase, putative 0.0199 0.026 0.8792
Loa Loa (eye worm) fibroinase 0.0052 0.0055 0.0764
Toxoplasma gondii ABC1 family protein 0.0224 0.0295 1
Schistosoma mansoni smdr2 0.0024 0.0015 0.0012
Echinococcus multilocularis cysteine protease 0.0052 0.0055 0.0052
Giardia lamblia Cysteinyl-tRNA synthetase 0.0089 0.0106 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0157 0.0201 0.6744
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0049 0.0763
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0066 0.2118
Echinococcus granulosus cathepsin L 0.0027 0.002 0.0016
Mycobacterium tuberculosis Probable lipase LipD 0.0224 0.0295 0.0332
Plasmodium vivax unspecified product 0.0017 0.0006 0.0062
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.001 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.002 0.0302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0055 0.0849
Brugia malayi hypothetical protein 0.0052 0.0054 0.0753
Echinococcus multilocularis lamin 0.0175 0.0226 0.0223
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0182 0.0236 0.7962

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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