Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | X box binding protein 1 | 0.0323 | 0.0481 | 0.0481 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqD | 0.0099 | 0.0097 | 0.5 |
Mycobacterium leprae | Possible phosphoglycerate mutase | 0.0099 | 0.0097 | 0.5 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Toxoplasma gondii | phosphoglycerate mutase PGMII | 0.0099 | 0.0097 | 1 |
Mycobacterium leprae | POSSIBLE HYDROLASE MUTT1 | 0.0099 | 0.0097 | 0.5 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0093 | 0.0086 | 0.0086 |
Mycobacterium tuberculosis | Possible hydrolase MutT1 | 0.0099 | 0.0097 | 0.5 |
Brugia malayi | UBASH3A protein homolog | 0.0099 | 0.0097 | 1 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0093 | 0.0086 | 0.0086 |
Trypanosoma cruzi | phosphoglycerate mutase protein, putative | 0.0099 | 0.0097 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0093 | 0.0086 | 0.0086 |
Giardia lamblia | Hypothetical protein | 0.3462 | 0.5872 | 0.5 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0074 | 0.0054 | 0.0054 |
Schistosoma mansoni | apoptosis regulator bax | 0.0093 | 0.0086 | 0.0086 |
Plasmodium vivax | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein | 0.2503 | 0.4225 | 0.4225 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0074 | 0.0054 | 0.0054 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative | 0.0099 | 0.0097 | 0.0097 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Leishmania major | hypothetical protein, conserved | 0.0099 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma brucei | Histidine phosphatase superfamily (branch 1), putative | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma cruzi | phosphoglycerate mutase family member 5, putative | 0.0099 | 0.0097 | 0.0097 |
Mycobacterium tuberculosis | PE-PGRS family protein PE_PGRS11 | 0.0099 | 0.0097 | 0.5 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.5866 | 1 | 1 |
Echinococcus granulosus | X box binding protein 1 | 0.0323 | 0.0481 | 0.0481 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0093 | 0.0086 | 0.8897 |
Plasmodium falciparum | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 1 |
Leishmania major | phosphoglycerate mutase protein, putative | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma brucei | phosphoglycerate mutase protein, putative | 0.0099 | 0.0097 | 0.0097 |
Plasmodium vivax | phosphoglucomutase-2, putative | 0.0099 | 0.0097 | 1 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0099 | 0.0097 | 0.0097 |
Mycobacterium tuberculosis | Conserved protein | 0.0099 | 0.0097 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.3462 | 0.5872 | 1 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 1 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.3462 | 0.5872 | 1 |
Entamoeba histolytica | phosphoglycerate mutase family protein. putative | 0.0099 | 0.0097 | 0.0165 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0074 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0093 | 0.0086 | 0.0086 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.5866 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0099 | 0.0097 | 0.0097 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0099 | 0.0097 | 1 |
Trypanosoma cruzi | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma brucei | Histidine phosphatase superfamily (branch 1), putative | 0.0099 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0023 | 0.0023 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0074 | 0.0054 | 0.0054 |
Mycobacterium tuberculosis | Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) | 0.0099 | 0.0097 | 0.5 |
Trypanosoma brucei | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 0.0097 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0099 | 0.0097 | 1 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0099 | 0.0097 | 0.0097 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0099 | 0.0097 | 1 |
Trypanosoma brucei | glycerolphosphate mutase, putative | 0.0099 | 0.0097 | 0.0097 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0099 | 0.0097 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0023 | 0.2331 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0099 | 0.0097 | 0.0097 |
Schistosoma mansoni | 6-phosphofructokinase | 0.5866 | 1 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0099 | 0.0097 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0086 | 0.0086 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) | 0.0099 | 0.0097 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative | 0.0099 | 0.0097 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0093 | 0.0086 | 0.0086 |
Trypanosoma brucei | Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative | 0.0099 | 0.0097 | 0.0097 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0074 | 0.0054 | 0.0091 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma cruzi | glycerolphosphate mutase, putative | 0.0099 | 0.0097 | 0.0097 |
Mycobacterium tuberculosis | Conserved protein | 0.0099 | 0.0097 | 0.5 |
Leishmania major | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 0.0097 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 1 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 1 |
Treponema pallidum | phosphoglyceromutase | 0.0099 | 0.0097 | 0.5 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) | 0.0099 | 0.0097 | 0.5 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Leishmania major | glycerolphosphate mutase, putative | 0.0099 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.3363 | 0.5702 | 0.5702 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0099 | 0.0097 | 1 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0099 | 0.0097 | 0.0165 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0023 | 0.2331 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.5767 | 0.983 | 0.983 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0074 | 0.0054 | 0.0054 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Leishmania major | fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein | 0.0099 | 0.0097 | 0.0097 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0099 | 0.0097 | 1 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0093 | 0.0086 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0099 | 0.0097 | 1 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.5866 | 1 | 1 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0099 | 0.0097 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.3462 | 0.5872 | 1 |
Trypanosoma cruzi | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 0.0097 |
Mycobacterium tuberculosis | Glucosyl-3-phosphoglycerate phosphatase GpgP | 0.0099 | 0.0097 | 0.5 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.5767 | 0.983 | 0.983 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0074 | 0.0054 | 0.0054 |
Giardia lamblia | Hypothetical protein | 0.3462 | 0.5872 | 0.5 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0099 | 0.0097 | 0.0097 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 1 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0099 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative | 0.0099 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.5866 | 1 | 1 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0074 | 0.0054 | 0.5551 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0099 | 0.0097 | 1 |
Trypanosoma cruzi | Histidine phosphatase superfamily (branch 1), putative | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.5767 | 0.983 | 0.983 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0099 | 0.0097 | 0.0165 |
Mycobacterium leprae | probable isochorismate synthase EntC | 0.0099 | 0.0097 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0093 | 0.0086 | 0.0086 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0074 | 0.0054 | 0.0054 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2503 | 0.4225 | 0.4225 |
Mycobacterium leprae | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0099 | 0.0097 | 0.5 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2503 | 0.4225 | 0.4225 |
Mycobacterium leprae | conserved hypothetical protein | 0.0099 | 0.0097 | 0.5 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0093 | 0.0086 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0323 | 0.0481 | 0.0481 |
Toxoplasma gondii | phosphoglycerate mutase | 0.0099 | 0.0097 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0099 | 0.0097 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.0023 | 0.0023 |
Trypanosoma brucei | Histidine phosphatase superfamily (branch 1), putative | 0.0099 | 0.0097 | 0.0097 |
Leishmania major | phosphoglycerate mutase family member 5, putative | 0.0099 | 0.0097 | 0.0097 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0093 | 0.0086 | 0.0086 |
Mycobacterium leprae | conserved hypothetical protein | 0.0099 | 0.0097 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2503 | 0.4225 | 0.4225 |
Trypanosoma cruzi | phosphoglycerate mutase protein, putative | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma cruzi | phosphoglycerate mutase family member 5, putative | 0.0099 | 0.0097 | 0.0097 |
Chlamydia trachomatis | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | 0.0099 | 0.0097 | 0.5 |
Plasmodium falciparum | phosphoglucomutase-2 | 0.0099 | 0.0097 | 1 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.5767 | 0.983 | 0.983 |
Onchocerca volvulus | 0.5866 | 1 | 1 | |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.5866 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.5866 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0099 | 0.0097 | 0.0097 |
Trypanosoma cruzi | glycerolphosphate mutase, putative | 0.0099 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | phosphoglycerate mutase | 0.0099 | 0.0097 | 0.0097 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0074 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.5767 | 0.983 | 0.983 |
Leishmania major | hypothetical protein, unknown function | 0.0099 | 0.0097 | 0.0097 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0099 | 0.0097 | 1 |
Mycobacterium tuberculosis | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0099 | 0.0097 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.