Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Serotonin receptor | 0.0017 | 0.0157 | 0.0107 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0314 | 0.0276 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0558 | 0.0558 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.2085 | 0.2085 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0314 | 0.0314 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0157 | 0.0157 |
Trichomonas vaginalis | hypothetical protein | 0.018 | 0.6678 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0.0314 | 0.0314 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.011 | 0.3871 | 0.3871 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0017 | 0.0157 | 0.0157 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.018 | 0.6678 | 0.5 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.018 | 0.6678 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.0314 | 0.3924 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0314 | 0.0276 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.018 | 0.6678 | 0.5 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | RNA binding protein | 0.0065 | 0.2085 | 0.218 |
Brugia malayi | Dopamine receptor protein 1 | 0.0017 | 0.0157 | 0.0107 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0558 | 0.0408 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0314 | 0.0314 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.0314 | 0.0314 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.2085 | 0.1959 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0314 | 0.0276 |
Echinococcus multilocularis | somatostatin receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0057 | 0.0057 |
Echinococcus granulosus | g-protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.018 | 0.6678 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | lamin | 0.0027 | 0.0558 | 0.0408 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | follicle stimulating hormone receptor | 0.0247 | 0.936 | 1 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.018 | 0.6678 | 0.5 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0017 | 0.0157 | 0.0107 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.011 | 0.3871 | 0.3871 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0314 | 0.0276 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0314 | 0.0314 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.018 | 0.6678 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Dopamine receptor | 0.0017 | 0.0157 | 0.0107 |
Brugia malayi | Melatonin receptor type 1A | 0.0017 | 0.0157 | 0.0107 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0314 | 0.0276 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0314 | 0.0314 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.3871 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.2085 | 0.1959 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0314 | 0.0276 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.0314 | 0.0314 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.2085 | 0.1959 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.011 | 0.3871 | 0.3774 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.0314 | 0.0314 |
Echinococcus multilocularis | serotonin receptor | 0.0263 | 1 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | larval opioid receptor | 0.0017 | 0.0157 | 0.0107 |
Schistosoma mansoni | lamin | 0.0027 | 0.0558 | 0.0408 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0314 | 0.016 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.0314 | 0.016 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0558 | 0.0558 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0314 | 0.0276 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0314 | 0.0314 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.0314 | 0.3924 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0314 | 0.0276 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.2085 | 0.218 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0314 | 0.016 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.2085 | 0.2085 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0558 | 0.0558 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0314 | 0.016 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.018 | 0.6678 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.2085 | 0.2085 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | GnHR receptor homolog | 0.0017 | 0.0157 | 0.0107 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | G protein-coupled receptor | 0.0017 | 0.0157 | 0.0107 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0157 | 0.0107 |
Echinococcus granulosus | lamin | 0.0027 | 0.0558 | 0.0558 |
Brugia malayi | Dopamine receptor protein 2 | 0.0017 | 0.0157 | 0.0107 |
Echinococcus granulosus | allatostatin A receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | sex peptide receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0314 | 0.0314 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0314 | 0.0276 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0314 | 0.0314 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.4256 | 0.4256 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.4256 | 0.4256 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | AKH receptor | 0.0017 | 0.0157 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0314 | 0.0314 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0314 | 0.0276 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0314 | 0.0314 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0314 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0314 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0017 | 0.0157 | 0.0107 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0558 | 0.0539 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.2085 | 0.1959 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0558 | 0.0558 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.2085 | 0.2085 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.0314 | 0.3924 |
Brugia malayi | sulfakinin receptor protein | 0.0017 | 0.0157 | 0.0107 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0314 | 0.0276 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0314 | 0.016 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0017 | 0.0157 | 0.0157 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.3871 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0314 | 0.0314 |
Brugia malayi | ORL1-like opioid receptor | 0.0017 | 0.0157 | 0.0107 |
Onchocerca volvulus | 0.0027 | 0.0558 | 1 | |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.4256 | 0.4513 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0157 | 0.0107 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0314 | 0.0314 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0558 | 0.0558 |
Echinococcus granulosus | fmrfamide receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.0157 | 0.0107 |
Echinococcus multilocularis | allatostatin A receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.0157 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0314 | 0.0314 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0017 | 0.0157 | 0.0107 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0263 | 1 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0247 | 0.936 | 0.936 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0314 | 0.016 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0314 | 0.0276 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0314 | 0.0314 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0017 | 0.0157 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Echinococcus granulosus | orexin receptor type 2 | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0017 | 0.0157 | 0.0107 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0314 | 0.016 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0314 | 0.0276 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0157 | 0.0107 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Onchocerca volvulus | 0.0021 | 0.0314 | 0.3924 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0314 | 0.016 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.3871 | 0.3774 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0314 | 0.0276 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0314 | 0.0314 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0314 | 0.016 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0157 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0314 | 0.016 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0558 | 0.0558 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.3871 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | somatostatin receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0314 | 0.0276 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | putative neuropeptide receptor | 0.0017 | 0.0157 | 0.0107 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.0314 | 0.0314 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0314 | 0.0314 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0017 | 0.0157 | 0.0157 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.018 | 0.6678 | 0.5 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0314 | 0.0314 |
Brugia malayi | hypothetical protein | 0.011 | 0.3871 | 0.41 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0539 | 0.0539 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0558 | 0.0558 |
Brugia malayi | RE15519p | 0.0017 | 0.0157 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.3871 | 0.5 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.2085 | 0.218 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | sex peptide receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | serotonin receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0558 | 0.0558 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0314 | 0.016 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0017 | 0.0157 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Onchocerca volvulus | 0.0027 | 0.0558 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0314 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.2085 | 0.2085 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0314 | 0.0276 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0314 | 0.0314 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0157 | 0.0107 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0558 | 0.0539 |
Echinococcus granulosus | neuropeptide s receptor | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.2085 | 0.1959 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0314 | 0.016 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0314 | 0.0314 |
Echinococcus multilocularis | serotonin receptor | 0.0263 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0314 | 0.0314 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0157 | 0.0157 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0.0314 | 0.0314 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0157 | 0.0157 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0314 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0314 | 0.0314 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0157 | 0.0157 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0314 | 0.0276 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0157 | 0.0157 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0017 | 0.0157 | 0.0107 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -13 % | DNDI: Inhibition of Human African Trypanosomiasis, SBRI 427, in vitro at 2 ug.mL-1 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.