TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 542.636 | Formula: C30H37F3N4O2
H donors: 1 H acceptors: 2 LogP: 5.59 Rotable bonds: 13
Rule of 5 violations (Lipinski): 2
SMILES: CCCCC(c1ccc(nc1)OC)NC(=O)CC1CCN(CC1)Cc1ccn(c1)c1ccc(cc1)C(F)(F)F
InChi: 1S/C30H37F3N4O2/c1-3-4-5-27(24-6-11-29(39-2)34-19-24)35-28(38)18-22-12-15-36(16-13-22)20-23-14-17-37(21-23)26-9-7-25(8-10-26)30(31,32)33/h6-11,14,17,19,21-22,27H,3-5,12-13,15-16,18,20H2,1-2H3,(H,35,38)
InChiKey: QHRSOSACJBYXIL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	melanin-concentrating hormone receptor 1	Starlite/ChEMBL	References
Homo sapiens	potassium voltage-gated channel, subfamily H (eag-related), member 2	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Loa Loa (eye worm)	voltage and ligand gated potassium channel	Get druggable targets OG5_128858	All targets in OG5_128858
Schistosoma mansoni	voltage-gated potassium channel	Get druggable targets OG5_128858	All targets in OG5_128858
Schistosoma japonicum	ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative	Get druggable targets OG5_128858	All targets in OG5_128858
Schistosoma mansoni	voltage-gated potassium channel	Get druggable targets OG5_128858	All targets in OG5_128858
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_128858	All targets in OG5_128858
Schistosoma japonicum	Potassium voltage-gated channel subfamily H member 2, putative	Get druggable targets OG5_128858	All targets in OG5_128858
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	Get druggable targets OG5_128858	All targets in OG5_128858
Echinococcus multilocularis	potassium voltage gated channel subfamily H	Get druggable targets OG5_128858	All targets in OG5_128858
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	Get druggable targets OG5_128858	All targets in OG5_128858
Schistosoma japonicum	ko:K04910 potassium voltage-gated channel, Eag-related subfamily H, member 7, putative	Get druggable targets OG5_128858	All targets in OG5_128858
Echinococcus granulosus	potassium voltage gated channel subfamily H	Get druggable targets OG5_128858	All targets in OG5_128858
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	Get druggable targets OG5_128858	All targets in OG5_128858

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	importin subunit beta 1	0.0032	0.0483	0.0517
Schistosoma mansoni	voltage-gated potassium channel	0.0049	0.0942	0.1009
Brugia malayi	exodeoxyribonuclease III family protein	0.0018	0.0083	0.0128
Echinococcus granulosus	carboxylesterase 5A	0.0046	0.0875	0.0937
Mycobacterium ulcerans	hypothetical protein	0.0026	0.0296	0.0386
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0045	0.0826	0.0885
Onchocerca volvulus	Huntingtin homolog	0.0138	0.3456	1
Toxoplasma gondii	3-oxo-5-alpha-steroid 4-dehydrogenase	0.0214	0.5607	1
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0046	0.0875	0.0937
Echinococcus granulosus	synaptic glycoprotein sc2	0.003	0.0417	0.0447
Trypanosoma cruzi	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0214	0.5607	1
Trichomonas vaginalis	conserved hypothetical protein	0.0026	0.0296	0.0386
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0026	0.031	0.0411
Brugia malayi	RNA, U transporter 1	0.0092	0.217	0.334
Schistosoma mansoni	gamma-secretase subunit aph-1	0.0245	0.6497	0.6959
Mycobacterium tuberculosis	Conserved protein	0.0026	0.0296	0.0749
Trypanosoma cruzi	Aph-1 protein, putative	0.0096	0.2268	0.3955
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0096	0.2272	0.2434
Schistosoma mansoni	synaptic glycoprotein sc2 related	0.003	0.0417	0.0447
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0119	0.2931	0.5156
Giardia lamblia	Synaptic glycoprotein SC2	0.003	0.0417	1
Mycobacterium ulcerans	glyoxalase GloA	0.0026	0.0296	0.0386
Loa Loa (eye worm)	hypothetical protein	0.0138	0.3456	0.3456
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0346	0.9336	0.9336
Brugia malayi	hypothetical protein	0.0138	0.3456	0.5319
Plasmodium falciparum	polyprenol reductase, putative	0.003	0.0417	0.127
Trypanosoma cruzi	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0214	0.5607	1
Trichomonas vaginalis	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0214	0.5607	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0033	0.0501	0.0772
Leishmania major	importin beta-1 subunit, putative	0.0026	0.031	0.0411
Onchocerca volvulus		0.003	0.0417	0.0383
Trichomonas vaginalis	synaptic glycoprotein sc2, putative	0.003	0.0417	0.0605
Brugia malayi	3-oxo-5-alpha-steroid 4-dehydrogenase 1	0.0214	0.5607	0.863
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0119	0.2931	0.5156
Schistosoma mansoni	aldehyde dehydrogenase	0.0119	0.2931	0.314
Loa Loa (eye worm)	carboxylesterase	0.0046	0.0875	0.0875
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0119	0.2931	1
Brugia malayi	GTP-binding nuclear protein RAN/TC4	0.0024	0.0241	0.0372
Leishmania major	3-oxo-5-alpha-steroid 4-dehydrogenase-like protein	0.0214	0.5607	1
Trypanosoma brucei	importin beta-1 subunit, putative	0.0032	0.0483	0.0724
Entamoeba histolytica	hypothetical protein	0.0026	0.031	0.0411
Schistosoma mansoni	tar DNA-binding protein	0.0133	0.3339	0.3576
Loa Loa (eye worm)	hypothetical protein	0.0039	0.066	0.066
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0096	0.2272	0.2434
Toxoplasma gondii	3-oxo-5-alpha-steroid 4-dehydrogenase	0.003	0.0417	0.0605
Plasmodium falciparum	glyoxalase I	0.0111	0.2716	1
Brugia malayi	TAR-binding protein	0.0133	0.3339	0.5139
Mycobacterium ulcerans	hypothetical protein	0.0026	0.0296	0.0386
Mycobacterium ulcerans	hypothetical protein	0.0026	0.0296	0.0386
Trypanosoma brucei	3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative	0.0214	0.5607	1
Loa Loa (eye worm)	hypothetical protein	0.0369	1	1
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0024	0.0241	0.0287
Echinococcus multilocularis	GTP binding nuclear protein Ran	0.0024	0.0241	0.0259
Echinococcus multilocularis	3 oxo 5 alpha steroid 4 dehydrogenase, C terminal	0.003	0.0417	0.0447
Schistosoma mansoni	4-hydroxyphenylpyruvate dioxygenase	0.0026	0.0296	0.0317
Toxoplasma gondii	glyoxalase I, putative	0.0111	0.2716	0.4766
Echinococcus multilocularis	gamma secretase subunit aph 1	0.0245	0.6497	0.6959
Schistosoma mansoni	hypothetical protein	0.0033	0.0501	0.0537
Brugia malayi	Carboxylesterase family protein	0.0046	0.0875	0.1347
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0096	0.2272	0.2272
Trichomonas vaginalis	importin beta-1, putative	0.0026	0.031	0.0411
Leishmania major	GTP-binding protein, putative	0.0024	0.0241	0.0287
Trypanosoma cruzi	lactoylglutathione lyase-like protein, putative	0.0111	0.2716	0.4766
Toxoplasma gondii	3-oxo-5-alpha-steroid 4-dehydrogenase	0.003	0.0417	0.0605
Mycobacterium ulcerans	biphenyl-2,3-diol 1,2-dioxygenase	0.0026	0.0296	0.0386
Onchocerca volvulus	Lactoylglutathione lyase homolog	0.0111	0.2716	0.7658
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0026	0.031	0.0411
Schistosoma mansoni	ran	0.0024	0.0241	0.0259
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0501	0.0501
Entamoeba histolytica	steroid 5-alpha reductase, putative	0.0214	0.5607	1
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0119	0.2931	0.314
Echinococcus granulosus	snurportin 1	0.0346	0.9336	1
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0133	0.3339	0.3339
Onchocerca volvulus	Huntingtin homolog	0.0138	0.3456	1
Trypanosoma brucei	Aph-1 protein, putative	0.0096	0.2268	0.3955
Trichomonas vaginalis	ran, putative	0.0024	0.0241	0.0287
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0096	0.2272	0.2434
Echinococcus multilocularis	snurportin 1	0.0346	0.9336	1
Schistosoma mansoni	tar DNA-binding protein	0.0133	0.3339	0.3576
Plasmodium vivax	glyoxalase I, putative	0.0026	0.0296	0.081
Plasmodium falciparum	glyoxalase I	0.0026	0.0296	0.081
Loa Loa (eye worm)	4-hydroxyphenylpyruvate dioxygenase	0.0026	0.0296	0.0296
Entamoeba histolytica	hypothetical protein	0.003	0.0417	0.0605
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0119	0.2931	0.5156
Echinococcus multilocularis	acetylcholinesterase	0.0046	0.0875	0.0937
Trichomonas vaginalis	synaptic glycoprotein sc2, putative	0.003	0.0417	0.0605
Schistosoma mansoni	ap endonuclease	0.0018	0.0083	0.0089
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0096	0.2272	0.2434
Toxoplasma gondii	aldehyde dehydrogenase	0.0119	0.2931	0.5156
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0042	0.0743	0.1196
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0096	0.2272	0.2434
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0096	0.2272	0.2434
Mycobacterium ulcerans	hypothetical protein	0.0026	0.0296	0.0386
Trichomonas vaginalis	conserved hypothetical protein	0.003	0.0417	0.0605
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0026	0.0296	0.0749
Schistosoma mansoni	tar DNA-binding protein	0.0133	0.3339	0.3576
Plasmodium vivax	GTP-binding nuclear protein RAN/TC4, putative	0.0024	0.0241	0.0601
Trypanosoma brucei	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.003	0.0417	0.0605
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0875	0.0875
Schistosoma mansoni	importin beta-1	0.0032	0.0483	0.0517
Echinococcus multilocularis	importin subunit beta 1	0.0032	0.0483	0.0517
Plasmodium vivax	glyoxalase I, putative	0.0111	0.2716	1
Brugia malayi	gamma-secretase subunit aph-1	0.0245	0.6497	1
Trichomonas vaginalis	conserved hypothetical protein	0.0026	0.0296	0.0386
Giardia lamblia	GTP-binding nuclear protein RAN/TC4	0.0024	0.0241	0.4736
Schistosoma mansoni	ap endonuclease	0.0018	0.0083	0.0089
Loa Loa (eye worm)	GTP-binding nuclear protein RAN/TC4	0.0024	0.0241	0.0241
Trichomonas vaginalis	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0214	0.5607	1
Trichomonas vaginalis	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0214	0.5607	1
Trichomonas vaginalis	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.003	0.0417	0.0605
Brugia malayi	Importin beta-1 subunit	0.0032	0.0483	0.0743
Mycobacterium ulcerans	hypothetical protein	0.0026	0.0296	0.0386
Loa Loa (eye worm)	TAR-binding protein	0.0133	0.3339	0.3339
Toxoplasma gondii	HEAT repeat-containing protein	0.0032	0.0483	0.0724
Brugia malayi	lactoylglutathione lyase	0.0111	0.2716	0.418
Mycobacterium ulcerans	hypothetical protein	0.0026	0.0296	0.0386
Trypanosoma brucei	GTP-binding nuclear protein rtb2, putative	0.0024	0.0241	0.0287
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0045	0.0826	0.1272
Leishmania major	glyoxalase I,trypanothione-dependent glyoxalase I	0.0111	0.2716	0.4766
Echinococcus multilocularis	synaptic glycoprotein sc2	0.003	0.0417	0.0447
Echinococcus granulosus	tar DNA binding protein	0.0133	0.3339	0.3576
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0045	0.0826	0.0826
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0018	0.0083	0.5
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0119	0.2931	0.314
Schistosoma mansoni	voltage-gated potassium channel	0.0049	0.0942	0.1009
Toxoplasma gondii	glyoxalase family protein	0.0026	0.0296	0.0386
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0018	0.0083	0.0089
Plasmodium vivax	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.003	0.0417	0.127
Mycobacterium tuberculosis	Conserved protein TB27.3	0.0026	0.0296	0.0749
Loa Loa (eye worm)	gamma-secretase subunit aph-1	0.0245	0.6497	0.6497
Mycobacterium tuberculosis	Conserved protein	0.0026	0.0296	0.0749
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0096	0.2272	0.3497
Schistosoma mansoni	synaptic glycoprotein sc2 related	0.003	0.0417	0.0447
Schistosoma mansoni	aldehyde dehydrogenase	0.0119	0.2931	0.314
Brugia malayi	4-hydroxyphenylpyruvate dioxygenase family protein	0.0026	0.0296	0.0456
Entamoeba histolytica	Ran family GTPase	0.0024	0.0241	0.0287
Brugia malayi	RNA binding protein	0.0133	0.3339	0.5139
Schistosoma mansoni	tar DNA-binding protein	0.0133	0.3339	0.3576
Loa Loa (eye worm)	hypothetical protein	0.003	0.0417	0.0417
Entamoeba histolytica	3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein	0.003	0.0417	0.0605
Mycobacterium tuberculosis	Cadmium inducible protein CadI	0.0026	0.0296	0.0749
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0048	0.0933	0.1437
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0042	0.0743	0.1196
Echinococcus multilocularis	acetylcholinesterase	0.0046	0.0875	0.0937
Loa Loa (eye worm)	hypothetical protein	0.0111	0.2716	0.2716
Plasmodium falciparum	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.003	0.0417	0.127
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0096	0.2272	0.2434
Entamoeba histolytica	trans-2,3-enoyl-CoA reductase, putative	0.003	0.0417	0.0605
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0048	0.0933	0.1437
Plasmodium vivax	importin-beta 2, putative	0.0032	0.0483	0.1519
Trichomonas vaginalis	conserved hypothetical protein	0.003	0.0417	0.0605
Trypanosoma cruzi	lactoylglutathione lyase-like protein, putative	0.0111	0.2716	0.4766
Loa Loa (eye worm)	acetylcholinesterase 1	0.0046	0.0875	0.0875
Mycobacterium ulcerans	hypothetical protein	0.0214	0.5607	1
Trypanosoma cruzi	Aph-1 protein, putative	0.0096	0.2268	0.3955
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0119	0.2931	0.5156
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0018	0.0083	0.0089
Echinococcus granulosus	3 oxo 5 alpha steroid 4 dehydrogenase C terminal	0.003	0.0417	0.0447
Brugia malayi	Synaptic glycoprotein SC2	0.003	0.0417	0.0642
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0483	0.0483
Toxoplasma gondii	GTP-binding nuclear protein ran/tc4	0.0024	0.0241	0.0287
Schistosoma mansoni	gynecophoral canal protein	0.0026	0.0296	0.0317
Loa Loa (eye worm)	RNA binding protein	0.0133	0.3339	0.3339
Schistosoma mansoni	tar DNA-binding protein	0.0133	0.3339	0.3576
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0933	0.0933
Loa Loa (eye worm)	hypothetical protein	0.0214	0.5607	0.5607
Schistosoma mansoni	hypothetical protein	0.0346	0.9336	1
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0026	0.031	0.0411
Loa Loa (eye worm)	hypothetical protein	0.003	0.0417	0.0417
Echinococcus granulosus	acetylcholinesterase	0.0046	0.0875	0.0937
Trypanosoma brucei	importin beta-1 subunit, putative	0.0032	0.0483	0.0724
Plasmodium falciparum	importin beta, putative	0.0032	0.0483	0.1519
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0045	0.0826	0.0885
Brugia malayi	RNA recognition motif domain containing protein	0.0133	0.3339	0.5139
Trichomonas vaginalis	synaptic glycoprotein sc2, putative	0.003	0.0417	0.0605
Brugia malayi	Carboxylesterase family protein	0.0046	0.0875	0.1347
Echinococcus granulosus	acetylcholinesterase	0.0046	0.0875	0.0937
Loa Loa (eye worm)	hypothetical protein	0.0138	0.3456	0.3456
Echinococcus granulosus	gamma secretase subunit aph 1	0.0245	0.6497	0.6959
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0048	0.0933	0.0933
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0018	0.0083	0.5
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0024	0.0241	0.0287
Plasmodium falciparum	GTP-binding nuclear protein RAN/TC4	0.0024	0.0241	0.0601
Schistosoma mansoni	ran	0.0024	0.0241	0.0259
Mycobacterium leprae	conserved hypothetical protein	0.0026	0.0296	0.5
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0018	0.0083	0.0083
Echinococcus granulosus	GTP binding nuclear protein Ran	0.0024	0.0241	0.0259
Echinococcus multilocularis	tar DNA binding protein	0.0133	0.3339	0.3576
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0875	0.0875
Trypanosoma cruzi	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.003	0.0417	0.0605
Mycobacterium ulcerans	glyoxalase GloA	0.0026	0.0296	0.0386
Echinococcus multilocularis	carboxylesterase 5A	0.0046	0.0875	0.0937
Plasmodium vivax	polyprenol reductase, putative	0.003	0.0417	0.127

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 0.005 uM	Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cells	ChEMBL.	19500979
IC50 (binding)	= 1 uM	Inhibition of human ERG expressed in CHO cells by patch clamp assay	ChEMBL.	19500979

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL549984

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1039465