Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0292 | 0.857 | 1 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0304 | 0.8938 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0017 | 0.002 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0431 | 0.0487 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.023 | 0.0213 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0017 | 0.002 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0248 | 0.1727 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.1166 | 0.1361 |
Trypanosoma brucei | unspecified product | 0.0027 | 0.0522 | 0.0564 |
Echinococcus multilocularis | bloom syndrome protein | 0.0046 | 0.1094 | 0.1079 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0039 | 0.0888 | 0.1018 |
Schistosoma mansoni | jumonji domain containing protein | 0.0059 | 0.1506 | 0.1757 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0397 | 0.0381 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0016 | 0.0188 | 0.0219 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0248 | 0.0068 |
Echinococcus granulosus | Carboxy terminal domain RNA polymerase II | 0.0012 | 0.0088 | 0.007 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.1564 | 0.1825 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.028 | 0.0327 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0431 | 0.0462 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0075 | 0.0062 |
Wolbachia endosymbiont of Brugia malayi | parvulin-like peptidyl-prolyl isomerase, PPID | 0.001 | 0.0019 | 0.5 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0034 | 0.0729 | 0.0885 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0039 | 0.0888 | 0.0974 |
Schistosoma mansoni | DNA helicase recq1 | 0.0019 | 0.028 | 0.0327 |
Toxoplasma gondii | PPIC-type PPIASE domain-containing protein | 0.001 | 0.0019 | 0.0121 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0027 | 0.0522 | 0.0564 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.1006 | 0.1107 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0016 | 0.0188 | 0.0171 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.1006 | 0.1107 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.023 | 0.0268 |
Loa Loa (eye worm) | acetyltransferase | 0.0148 | 0.4195 | 0.5193 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0083 | 0.0082 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0046 | 0.1094 | 0.1339 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0061 | 0.1564 | 0.155 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0039 | 0.0888 | 0.0974 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0018 | 0.0246 | 0.0229 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0031 | 0.0645 | 0.5684 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0431 | 0.0446 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0017 | 0.002 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0431 | 0.0446 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0012 | 0.0088 | 0.0102 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0038 | 0.0853 | 0.0935 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0088 | 0.0087 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0431 | 0.4792 |
Plasmodium vivax | JmjC domain containing protein | 0.0016 | 0.0188 | 0.1127 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0431 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0248 | 0.0287 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.1558 | 0.1543 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0188 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.2239 | 0.2762 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.0188 | 0.0189 |
Trypanosoma brucei | unspecified product | 0.0039 | 0.0888 | 0.0974 |
Echinococcus granulosus | dna polymerase eta | 0.0064 | 0.1667 | 0.1652 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0012 | 0.0075 | 0.0062 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0188 | 0.0189 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0898 | 0.9678 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.1558 | 0.1543 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0083 | 0.2239 | 0.2762 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0019 | 0.028 | 0.2419 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0431 | 0.0514 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0045 | 0.1079 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.1006 | 0.1107 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0017 | 0.002 |
Schistosoma mansoni | rotamase | 0.0034 | 0.0729 | 0.0851 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0039 | 0.0888 | 0.1082 |
Echinococcus multilocularis | zinc finger protein | 0.0023 | 0.0415 | 0.0398 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0144 | 0.4077 | 0.4549 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.1558 | 0.1857 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.016 | 0.457 | 1 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.1368 | 0.1679 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0033 | 0.0705 | 0.077 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0705 | 0.077 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0059 | 0.1506 | 0.1491 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0024 | 0.0449 | 0.0482 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0248 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0064 | 0.1667 | 0.205 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0621 | 0.0724 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0038 | 0.0853 | 0.5476 |
Onchocerca volvulus | 0.0048 | 0.1166 | 0.1658 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Giardia lamblia | DINP protein human, muc B family | 0.0039 | 0.0888 | 0.9873 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0431 | 0.0446 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0045 | 0.1079 | 0.1064 |
Onchocerca volvulus | 0.0024 | 0.0431 | 0.0596 | |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0017 | 0.002 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0621 | 0.0724 |
Schistosoma mansoni | protein phosphatase 2C | 0.0016 | 0.0188 | 0.0219 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.003 | 0.0634 | 0.4072 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0807 | 0.0791 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0449 | 0.0453 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0176 | 0.0176 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.1166 | 0.1428 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.028 | 0.18 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0027 | 0.0522 | 0.0564 |
Leishmania major | DNA polymerase eta, putative | 0.0064 | 0.1667 | 0.1847 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0188 | 0.0212 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.1166 | 0.1361 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0045 | 0.1079 | 0.1243 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.2239 | 0.2613 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0188 | 0.0212 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0024 | 0.0449 | 0.0482 |
Plasmodium falciparum | NLI interacting factor-like phosphatase, putative | 0.0012 | 0.0088 | 0.0154 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0188 | 0.0212 |
Echinococcus multilocularis | tumor protein p63 | 0.0339 | 1 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0059 | 0.1506 | 0.1491 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.0898 | 1 |
Onchocerca volvulus | 0.003 | 0.0621 | 0.0871 | |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0039 | 0.0888 | 0.1036 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0083 | 0.2239 | 0.2762 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.1667 | 0.205 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0019 | 0.028 | 0.2499 |
Echinococcus multilocularis | dna polymerase kappa | 0.0039 | 0.0888 | 0.0872 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.1564 | 0.1825 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.0729 | 0.0885 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.1558 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0729 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0431 | 0.0514 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0048 | 0.1166 | 0.1151 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0019 | 0.028 | 0.0264 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0045 | 0.1079 | 0.6926 |
Trypanosoma brucei | Mitochondrial import inner membrane translocase subunit TIM50 | 0.0012 | 0.0088 | 0.0077 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0431 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.1142 | 0.1398 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0431 | 0.0446 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.0729 | 0.0804 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0047 | 0.1142 | 0.1127 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.1558 | 0.1818 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0048 | 0.1166 | 0.1151 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0017 | 0.002 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0033 | 0.0705 | 0.4527 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0075 | 0.0071 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0012 | 0.0075 | 0.0062 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0431 | 0.0446 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.0188 | 0.0189 |
Schistosoma mansoni | bromodomain containing protein | 0.0067 | 0.1751 | 0.2043 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.1142 | 0.1332 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0188 | 0.0212 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0088 | 0.0077 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0431 | 0.5 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0039 | 0.0888 | 0.0974 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0012 | 0.0075 | 0.0062 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0144 | 0.4077 | 0.4549 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0248 | 0.0217 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0016 | 0.0188 | 0.0171 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0017 | 0.002 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0021 | 0.0356 | 0.0422 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0431 | 0.4792 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0188 | 0.0212 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0209 | 0.6069 | 0.7522 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0621 | 0.0604 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.1558 | 0.1857 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0048 | 0.1166 | 0.1151 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0621 | 0.075 |
Leishmania major | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.1062 | 0.1298 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.0075 | 0.0062 |
Schistosoma mansoni | DNA polymerase eta | 0.0064 | 0.1667 | 0.1945 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.1558 | 0.1818 |
Trypanosoma brucei | unspecified product | 0.0027 | 0.0522 | 0.0564 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0048 | 0.1166 | 0.1428 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0144 | 0.4077 | 0.4549 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0431 | 0.0446 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0075 | 0.0062 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0431 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0176 | 0.0176 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0148 | 0.4195 | 0.4185 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0016 | 0.0188 | 0.1205 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0248 | 0.2037 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.1641 | 0.1627 |
Leishmania major | DNA polymerase eta, putative | 0.0038 | 0.0853 | 0.0935 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0397 | 0.0464 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0083 | 0.2239 | 0.2613 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0431 | 0.0514 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0012 | 0.0075 | 0.0062 |
Brugia malayi | glutaminase DH11.1 | 0.0275 | 0.8063 | 1 |
Schistosoma mansoni | glutaminase | 0.0275 | 0.8063 | 0.9408 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.028 | 0.18 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0027 | 0.0522 | 0.0564 |
Onchocerca volvulus | 0.0011 | 0.0038 | 0.003 | |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0621 | 0.3985 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0397 | 0.0381 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0059 | 0.1506 | 0.1491 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.112 | 0.1371 |
Mycobacterium ulcerans | hypothetical protein | 0.016 | 0.457 | 0.5628 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.0705 | 0.077 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0012 | 0.0075 | 0.0062 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.1368 | 0.1353 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0019 | 0.028 | 0.0264 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.1142 | 0.1332 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0248 | 0.0287 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0016 | 0.0188 | 0.1205 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.0705 | 0.0774 |
Loa Loa (eye worm) | glutaminase | 0.0275 | 0.8063 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1166 | 0.1428 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0248 | 0.0287 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.1368 | 0.1679 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0019 | 0.028 | 0.0264 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0012 | 0.0075 | 0.0062 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0012 | 0.0075 | 0.0478 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0148 | 0.4195 | 0.5193 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0083 | 0.2239 | 0.2226 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.023 | 0.0213 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0415 | 0.0484 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0017 | 0.002 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0431 | 0.4792 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.1368 | 0.1353 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0039 | 0.0888 | 0.1036 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0248 | 0.0287 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0046 | 0.1094 | 0.1262 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.1564 | 0.1923 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0431 | 0.0487 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0039 | 0.0888 | 0.1538 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0148 | 0.4195 | 0.4895 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0039 | 0.0888 | 0.1004 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.2239 | 0.2613 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0431 | 0.0446 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0012 | 0.0075 | 0.0478 |
Giardia lamblia | Nuclear LIM interactor-interacting factor 1 | 0.0012 | 0.0088 | 0.0159 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0304 | 0.8938 | 1 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0083 | 0.2239 | 0.2226 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0064 | 0.1667 | 0.1847 |
Toxoplasma gondii | Dullard family phosphatase domain-containing protein | 0.0012 | 0.0088 | 0.0563 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0045 | 0.1079 | 0.6926 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0141 | 0.3999 | 0.3989 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.1215 | 0.1417 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0304 | 0.8938 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0275 | 0.8063 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0339 | 0.0396 |
Onchocerca volvulus | 0.005 | 0.1215 | 0.1728 | |
Brugia malayi | Pre-SET motif family protein | 0.0209 | 0.6069 | 0.7522 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.1564 | 0.1923 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.0987 | 0.1205 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0188 | 0.0212 |
Onchocerca volvulus | 0.0238 | 0.6948 | 1 | |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0016 | 0.0188 | 0.0171 |
Loa Loa (eye worm) | glutaminase 2 | 0.0275 | 0.8063 | 1 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0176 | 0.0176 |
Leishmania major | hypothetical protein, conserved | 0.0012 | 0.0088 | 0.0077 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.1558 | 0.1725 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0188 | 0.0212 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0578 | 0.0697 |
Entamoeba histolytica | NLI interacting factor-like phosphatase domain-containing protein | 0.0012 | 0.0088 | 0.0975 |
Schistosoma mansoni | apoptosis regulator bax | 0.0083 | 0.2239 | 0.2613 |
Echinococcus granulosus | zinc finger protein | 0.0023 | 0.0415 | 0.0398 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0045 | 0.1079 | 0.1243 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3921 | 0.4853 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.1506 | 0.185 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1215 | 0.1488 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.1641 | 0.1627 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0339 | 0.04 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0176 | 0.0176 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0012 | 0.0075 | 0.0062 |
Leishmania major | DNA damage repair protein, putative | 0.0012 | 0.0075 | 0.0062 |
Schistosoma mansoni | jumonji domain containing protein | 0.0016 | 0.0188 | 0.0219 |
Entamoeba histolytica | recQ family helicase, putative | 0.0024 | 0.0449 | 0.4995 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0039 | 0.0888 | 0.0872 |
Brugia malayi | Bromodomain containing protein | 0.0079 | 0.2109 | 0.2599 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0039 | 0.0888 | 0.1082 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.1368 | 0.1353 |
Trichomonas vaginalis | set domain proteins, putative | 0.0238 | 0.6948 | 0.8602 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0024 | 0.0449 | 0.0482 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0431 | 0.0446 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0019 | 0.028 | 0.0264 |
Mycobacterium ulcerans | glutaminase | 0.0275 | 0.8063 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0039 | 0.0888 | 0.9883 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.1558 | 0.1857 |
Echinococcus multilocularis | phd:f box containing protein | 0.0016 | 0.0188 | 0.0171 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0036 | 0.0803 | 0.0937 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0016 | 0.0188 | 0.0171 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0431 | 0.0462 |
Echinococcus granulosus | phd:f box containing protein | 0.0016 | 0.0188 | 0.0171 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0176 | 0.0205 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0587 | 0.0571 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0083 | 0.2239 | 0.2226 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.1197 | 0.7684 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0039 | 0.0888 | 0.0872 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.028 | 0.0327 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0431 | 0.0514 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0064 | 0.1667 | 0.1847 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0016 | 0.0188 | 0.133 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0039 | 0.0888 | 0.0974 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0012 | 0.0088 | 0.0102 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0807 | 0.0791 |
Echinococcus granulosus | bloom syndrome protein | 0.0046 | 0.1094 | 0.1079 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0039 | 0.0888 | 0.1538 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0016 | 0.0188 | 0.0171 |
Brugia malayi | Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 | 0.0012 | 0.0088 | 0.0087 |
Schistosoma mansoni | DNA helicase recq5 | 0.0019 | 0.028 | 0.0327 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.1368 | 0.1353 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0017 | 0.002 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0018 | 0.0246 | 0.0229 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0188 | 0.0212 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0189 | 0.5453 | 0.5445 |
Plasmodium vivax | NLI interacting factor-like phosphatase, putative | 0.0012 | 0.0088 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.028 | 0.0327 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0189 | 0.5453 | 0.5445 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0248 | 0.0287 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0881 | 0.1074 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0047 | 0.1142 | 0.1127 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0048 | 0.1166 | 0.1151 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0016 | 0.0188 | 0.0171 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.1166 | 0.1428 |
Loa Loa (eye worm) | RecQ helicase | 0.0046 | 0.1094 | 0.1339 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0048 | 0.1166 | 0.1658 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0188 | 0.0212 |
Schistosoma mansoni | phd/f-box containing protein | 0.0016 | 0.0188 | 0.0219 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0033 | 0.0705 | 0.077 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0012 | 0.0075 | 0.0062 |
Echinococcus granulosus | expressed protein | 0.0034 | 0.0729 | 0.0713 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.0898 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0064 | 0.1667 | 0.1652 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0431 | 0.0462 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0304 | 0.8938 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.0705 | 0.7848 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0016 | 0.0188 | 0.0189 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0017 | 0.002 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0052 | 0.129 | 0.1425 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.1558 | 0.3078 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0046 | 0.1094 | 0.1262 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0048 | 0.1166 | 0.1361 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.187 | 0.2303 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.023 | 0.0268 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0017 | 0.002 |
Echinococcus multilocularis | expressed protein | 0.0034 | 0.0729 | 0.0713 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.1368 | 0.1596 |
Echinococcus multilocularis | 0.0012 | 0.0088 | 0.007 | |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1368 | 0.1679 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0176 | 0.0205 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0019 | 0.028 | 0.0327 |
Echinococcus granulosus | dna polymerase kappa | 0.0039 | 0.0888 | 0.0872 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0012 | 0.0075 | 0.0087 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0039 | 0.0888 | 0.1004 |
Brugia malayi | polk-prov protein | 0.0012 | 0.0075 | 0.0071 |
Echinococcus multilocularis | Carboxy terminal domain RNA polymerase II | 0.0012 | 0.0088 | 0.007 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0083 | 0.2239 | 0.2226 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0017 | 0.002 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.1006 | 0.1107 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0017 | 0.002 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.004 | 0.0926 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0039 | 0.0888 | 0.1018 |
Plasmodium vivax | NLI interacting factor-like phosphatase, putative | 0.0012 | 0.0088 | 0.013 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0016 | 0.0188 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0083 | 0.0097 |
Leishmania major | DNA polymerase kappa, putative | 0.0012 | 0.0075 | 0.0062 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0621 | 0.5438 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0039 | 0.0888 | 0.0974 |
Echinococcus granulosus | CTD small phosphatase protein like | 0.0012 | 0.0088 | 0.007 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.2239 | 0.2613 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 100 uM | Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Visible Spectrophotometer method | ChEMBL. | 21788136 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.