Detailed information for compound 1041811

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 162.144 | Formula: C5H10N2O4
  • H donors: 3 H acceptors: 3 LogP: -3.65 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)NCC(C(=O)O)N
  • InChi: 1S/C5H10N2O4/c1-11-5(10)7-2-3(6)4(8)9/h3H,2,6H2,1H3,(H,7,10)(H,8,9)
  • InChiKey: ACKMHVGECBCNMN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0123 0.0544 0.2018
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0086 0.032
Schistosoma mansoni RAR-like nuclear receptor 0.0035 0.0086 0.032
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0091 0.0378 0.1404
Echinococcus granulosus acetylcholinesterase 0.0541 0.2693 1
Onchocerca volvulus 0.0091 0.0378 0.1141
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0018 0.0097
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0086 0.032
Loa Loa (eye worm) twinkle helicase 0.0126 0.0555 0.2061
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.0078 0.0291
Echinococcus multilocularis smad 0.0019 0.0003 0.0011
Schistosoma mansoni hypothetical protein 0.0193 0.0901 0.3346
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.026 0.0966
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0035 0.0086 0.032
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0086 0.032
Echinococcus granulosus smad 0.0019 0.0003 0.0011
Chlamydia trachomatis replicative DNA helicase 0.044 0.2174 0.5
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0086 0.032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0035 0.0086 0.032
Loa Loa (eye worm) carboxylesterase 0.0091 0.0378 0.1404
Echinococcus granulosus mothers against decapentaplegic 5 0.0019 0.0003 0.0011
Echinococcus multilocularis ecdysone induced protein 78C 0.0035 0.0086 0.032
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0055 0.2081
Echinococcus granulosus carboxylesterase 5A 0.0541 0.2693 1
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0091 0.0378 0.0377
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0035 0.0086 0.032
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0114 0.0425
Onchocerca volvulus Bile acid receptor homolog 0.0035 0.0086 0.0029
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0163 0.0746 0.4437
Echinococcus multilocularis thyroid hormone receptor alpha 0.0035 0.0086 0.032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0035 0.0086 0.032
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0002 0.0006
Echinococcus granulosus Smad4 0.0019 0.0003 0.0011
Entamoeba histolytica hypothetical protein 0.0123 0.0544 1
Echinococcus multilocularis neuropeptide receptor A26 0.0534 0.2659 0.9873
Loa Loa (eye worm) acetylcholinesterase 1 0.0541 0.2693 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0035 0.0086 0.032
Brugia malayi hypothetical protein 0.0091 0.0378 0.1404
Loa Loa (eye worm) hypothetical protein 0.0091 0.0378 0.1404
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0035 0.0086 0.032
Schistosoma mansoni ap endonuclease 0.0021 0.0018 0.0066
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0018 0.0097
Loa Loa (eye worm) hypothetical protein 0.0205 0.0966 0.3588
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0114 0.0425
Loa Loa (eye worm) hypothetical protein 0.0091 0.0378 0.1404
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0007
Loa Loa (eye worm) transcription factor SMAD2 0.0272 0.1308 0.4856
Echinococcus multilocularis peregrin 0.0033 0.0078 0.0291
Loa Loa (eye worm) hypothetical protein 0.0035 0.0086 0.032
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0002 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0018 0.0097
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0109 0.0467 0.1736
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0035 0.0086 0.032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0035 0.0086 0.032
Loa Loa (eye worm) hypothetical protein 0.0039 0.0107 0.0399
Echinococcus multilocularis para nitrobenzyl esterase 0.0091 0.0378 0.1404
Echinococcus multilocularis mothers against decapentaplegic 5 0.0019 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0057 0.02 0.0742
Leishmania major mitochondrial DNA polymerase beta 0.0344 0.1679 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0018 0.0002 0.0007
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0163 0.0746 0.4437
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0086 0.032
Onchocerca volvulus 0.0543 0.2706 1
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0055 0.0321
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0091 0.0378 0.1341
Echinococcus multilocularis Smad4 0.0019 0.0003 0.0011
Onchocerca volvulus 0.0091 0.0378 0.1141
Loa Loa (eye worm) hypothetical protein 0.0091 0.0378 0.1404
Schistosoma mansoni smad 0.0019 0.0003 0.0011
Schistosoma mansoni hypothetical protein 0.0193 0.0901 0.3346
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0378 0.1404
Loa Loa (eye worm) hypothetical protein 0.0091 0.0378 0.1404
Schistosoma mansoni gliotactin 0.0091 0.0378 0.1404
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0086 0.032
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0035 0.0086 0.032
Trichomonas vaginalis set domain proteins, putative 0.0543 0.2706 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0035 0.0086 0.032
Onchocerca volvulus 0.0055 0.019 0.0426
Echinococcus granulosus FTZ F1 alpha 0.0035 0.0086 0.032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0035 0.0086 0.032
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0018 0.0002 0.0007
Brugia malayi nuclear hormone receptor 0.0035 0.0086 0.032
Loa Loa (eye worm) hypothetical protein 0.0035 0.0086 0.032
Schistosoma mansoni smad1 5 8 and 0.0019 0.0003 0.0011
Schistosoma mansoni hypothetical protein 0.0055 0.019 0.0707
Onchocerca volvulus 0.0091 0.0378 0.1141
Brugia malayi MH2 domain containing protein 0.0019 0.0003 0.0011
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0109 0.0467 0.1736
Onchocerca volvulus 0.0091 0.0378 0.1141
Brugia malayi hypothetical protein 0.0018 0.0002 0.0007
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0344 0.1679 1
Toxoplasma gondii hypothetical protein 0.0055 0.0193 0.741
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.02 0.0742
Echinococcus granulosus survival motor neuron protein 1 0.0269 0.1294 0.4806
Brugia malayi MH2 domain containing protein 0.0272 0.1308 0.4856
Loa Loa (eye worm) hypothetical protein 0.0057 0.0201 0.0745
Loa Loa (eye worm) hypothetical protein 0.0068 0.026 0.0966
Schistosoma mansoni hypothetical protein 0.0033 0.0078 0.0291
Leishmania major hypothetical protein, conserved 0.0029 0.0055 0.0321
Echinococcus multilocularis neuroligin 0.0091 0.0378 0.1404
Schistosoma mansoni Smad4 0.0019 0.0003 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0035 0.0086 0.032
Loa Loa (eye worm) hypothetical protein 0.0035 0.0086 0.032
Loa Loa (eye worm) Smad1 0.0019 0.0003 0.0011
Onchocerca volvulus 0.0091 0.0378 0.1141
Loa Loa (eye worm) hypothetical protein 0.0091 0.0378 0.1404
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0068 0.026 1
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0002 0.0007
Echinococcus multilocularis acetylcholinesterase 0.0541 0.2693 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0035 0.0086 0.032
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0378 0.1404
Loa Loa (eye worm) carboxylesterase 0.0541 0.2693 1
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0078 0.2976
Brugia malayi jmjC domain containing protein 0.004 0.0114 0.0425
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0035 0.0086 0.032
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0163 0.0746 0.4437
Onchocerca volvulus Protein ultraspiracle homolog 0.0035 0.0086 0.0029
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0477 0.2366 0.8786
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0035 0.0086 0.032
Loa Loa (eye worm) PHD-finger family protein 0.0033 0.0078 0.0291
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0035 0.0086 0.032
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0035 0.0086 0.032
Echinococcus granulosus BC026374 protein S09 family 0.0091 0.0378 0.1404
Schistosoma mansoni Replicative DNA helicase 0.044 0.2174 0.8071
Brugia malayi Carboxylesterase family protein 0.0541 0.2693 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0055 0.0205
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0018 0.0066
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1519 0.7734 0.7733
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0068 0.026 0.0966
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0035 0.0086 0.032
Echinococcus multilocularis neuropeptide s receptor 0.0534 0.2659 0.9873
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0018 0.0066
Plasmodium vivax SET domain protein, putative 0.0068 0.026 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0035 0.0086 0.032
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0002 0.0006
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0157 0.0924
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0114 0.0425
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0007
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0018 0.0016
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0055 0.2081
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0035 0.0086 0.032
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0002 0.0007
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0066 0.0247 0.0918
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.026 0.0966
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0157 0.0924
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0344 0.1679 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0018 0.0002 0.0007
Schistosoma mansoni coup transcription factor 0.0035 0.0086 0.032
Echinococcus granulosus neuropeptide s receptor 0.0534 0.2659 0.9873
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0048 0.0157 0.0924
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0002 0.0006
Brugia malayi jmjC domain containing protein 0.0109 0.0467 0.1736
Schistosoma mansoni acetylcholinesterase 0.0091 0.0378 0.1404
Echinococcus granulosus histone lysine methyltransferase setb 0.0068 0.026 0.0966
Schistosoma mansoni ap endonuclease 0.0021 0.0018 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0035 0.0086 0.032
Brugia malayi nuclear receptor RXR 0.0018 0.0002 0.0007
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0068 0.026 0.0966
Loa Loa (eye worm) MH2 domain-containing protein 0.0272 0.1308 0.4856
Loa Loa (eye worm) steroid hormone receptor 0.0035 0.0086 0.032
Plasmodium falciparum phd finger protein, putative 0.0033 0.0078 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0003 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0035 0.0086 0.032
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0019 0.0003 0.0011
Echinococcus granulosus ecdysone induced protein 78C 0.0035 0.0086 0.032
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.044 0.2174 1
Echinococcus multilocularis survival motor neuron protein 1 0.0269 0.1294 0.4806
Echinococcus granulosus neuroligin 0.0091 0.0378 0.1404
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0007
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0002 0.0006
Brugia malayi Pre-SET motif family protein 0.0477 0.2366 0.8786
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0007
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0059 0.0211 0.1249
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0261 0.0967
Brugia malayi Carboxylesterase family protein 0.0541 0.2693 1
Schistosoma mansoni retinoic acid receptor RXR 0.0035 0.0086 0.032
Echinococcus granulosus jumonji domain containing protein 0.0046 0.0145 0.054
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0018 0.0097
Schistosoma mansoni smad1 5 8 and 0.0019 0.0003 0.0011
Brugia malayi ecdysteroid receptor 0.0035 0.0086 0.032
Brugia malayi PHD-finger family protein 0.0033 0.0078 0.0291
Loa Loa (eye worm) hypothetical protein 0.0035 0.0086 0.032
Giardia lamblia PHD finger protein 15 0.0033 0.0078 1
Mycobacterium ulcerans replicative DNA helicase DnaB 0.044 0.2174 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0055 0.6992
Echinococcus granulosus acetylcholinesterase 0.0541 0.2693 1
Brugia malayi isocitrate dehydrogenase 0.0018 0.0002 0.0006
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0091 0.0378 0.1404
Mycobacterium tuberculosis Conserved hypothetical protein 0.0181 0.084 0.0839
Schistosoma mansoni BC026374 protein (S09 family) 0.0091 0.0378 0.1404
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0035 0.0086 0.032
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0114 0.0425
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0035 0.0086 0.032
Mycobacterium leprae Conserved hypothetical protein 0.0576 0.2877 1
Entamoeba histolytica hypothetical protein 0.0123 0.0544 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.0078 0.0291
Trichomonas vaginalis spcc417.12 protein, putative 0.0091 0.0378 0.1341
Schistosoma mansoni nuclear hormone receptor 0.0035 0.0086 0.032
Entamoeba histolytica hypothetical protein 0.0123 0.0544 1
Schistosoma mansoni transcription factor LCR-F1 0.0123 0.0544 0.2018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0035 0.0086 0.032
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.019 0.0707
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0002 0.0006
Mycobacterium tuberculosis Carboxylesterase LipT 0.0091 0.0378 0.0377
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.026 0.0966
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0018 0.063
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0003 0.0011
Loa Loa (eye worm) carboxylesterase 0.0091 0.0378 0.1404
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.02 0.0742
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0035 0.0086 0.032
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0091 0.0378 0.0377
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0114 0.0425
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0078 0.2976
Brugia malayi Carboxylesterase family protein 0.0091 0.0378 0.1404
Brugia malayi Steroid receptor seven-up type 2 0.0035 0.0086 0.032
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0002 0.0007
Schistosoma mansoni hypothetical protein 0.0039 0.0107 0.0399
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0002 0.0006
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0035 0.0086 0.032
Loa Loa (eye worm) hypothetical protein 0.0091 0.0378 0.1404
Loa Loa (eye worm) hypothetical protein 0.0541 0.2693 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0086 0.032
Loa Loa (eye worm) hypothetical protein 0.0035 0.0086 0.032
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0086 0.032
Echinococcus granulosus TGF beta signal transducer SmadC 0.0019 0.0003 0.0011
Brugia malayi Smad1 0.0019 0.0003 0.0011
Echinococcus multilocularis acetylcholinesterase 0.0541 0.2693 1
Echinococcus granulosus geminin 0.0193 0.0901 0.3346
Brugia malayi Carboxylesterase family protein 0.0091 0.0378 0.1404
Mycobacterium ulcerans carboxylesterase, LipT 0.0091 0.0378 0.1672
Echinococcus multilocularis geminin 0.0193 0.0901 0.3346
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0078 0.2976
Schistosoma mansoni neuroligin 3 (S09 family) 0.0091 0.0378 0.1404
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0018 0.0066
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.0078 0.0291
Brugia malayi Carboxylesterase family protein 0.0091 0.0378 0.1404
Schistosoma mansoni hypothetical protein 0.0123 0.0544 0.2018
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0035 0.0086 0.032
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0018 0.0002 0.0007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0018 0.2116
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0091 0.0378 0.1404
Brugia malayi N-terminal motif family protein 0.0205 0.0966 0.3588
Brugia malayi hypothetical protein 0.0019 0.0003 0.0011
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0541 0.2693 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0035 0.0086 0.032
Schistosoma mansoni smad1 5 8 and 0.0019 0.0003 0.0011
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0019 0.0003 0.0011
Brugia malayi hypothetical protein 0.0123 0.0544 0.2018
Schistosoma mansoni survival motor neuron protein 0.0055 0.019 0.0707
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0107 0.0399
Echinococcus granulosus neuropeptide receptor A26 0.0534 0.2659 0.9873
Loa Loa (eye worm) hypothetical protein 0.0541 0.2693 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0035 0.0086 0.032
Echinococcus multilocularis carboxylesterase 5A 0.0541 0.2693 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0035 0.0086 0.032
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0205 0.0966 0.3379
Brugia malayi steroid hormone receptor 0.0035 0.0086 0.032
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0002 0.0006
Schistosoma mansoni steroid hormone receptor ad4bp 0.0035 0.0086 0.032
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0035 0.0086 0.0029
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0086 0.032
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0344 0.1679 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0018 0.0066
Brugia malayi nuclear receptor NHR-88 0.0035 0.0086 0.032
Brugia malayi MH1 domain containing protein 0.0019 0.0003 0.0011
Brugia malayi MH1 domain containing protein 0.0019 0.0003 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0035 0.0086 0.032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0091 0.0378 0.1404
Toxoplasma gondii exonuclease III APE 0.0021 0.0018 0.063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0035 0.0086 0.032
Entamoeba histolytica hypothetical protein 0.0123 0.0544 1
Schistosoma mansoni thyroid hormone receptor 0.0035 0.0086 0.032
Treponema pallidum replicative DNA helicase (dnaB) 0.044 0.2174 1
Schistosoma mansoni jumonji domain containing protein 0.0086 0.0352 0.1308
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0055 0.6992
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.02 0.0742
Brugia malayi Bromodomain containing protein 0.0033 0.0078 0.0291
Loa Loa (eye worm) hypothetical protein 0.0269 0.1294 0.4806
Mycobacterium ulcerans hypothetical protein 0.0181 0.084 0.3816
Loa Loa (eye worm) hypothetical protein 0.0033 0.0078 0.0291
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0068 0.026 0.0966
Onchocerca volvulus 0.0068 0.026 0.0692
Brugia malayi MH2 domain containing protein 0.0019 0.0003 0.0011
Echinococcus granulosus peregrin 0.0033 0.0078 0.0291
Loa Loa (eye worm) hypothetical protein 0.0035 0.0086 0.032
Brugia malayi photoreceptor-specific nuclear receptor 0.0035 0.0086 0.032
Brugia malayi hypothetical protein 0.0269 0.1294 0.4806
Echinococcus multilocularis jumonji domain containing protein 0.0046 0.0145 0.054
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0055 0.0321
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0157 0.0924
Echinococcus multilocularis FTZ F1 alpha 0.0035 0.0086 0.032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0123 0.0544 0.2018
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0055 0.0321
Onchocerca volvulus 0.0035 0.0086 0.0029
Brugia malayi Pre-SET motif family protein 0.0068 0.026 0.0966
Loa Loa (eye worm) hypothetical protein 0.0035 0.0086 0.032
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0002 0.0006
Echinococcus multilocularis BC026374 protein (S09 family) 0.0091 0.0378 0.1404
Echinococcus granulosus para nitrobenzyl esterase 0.0091 0.0378 0.1404
Brugia malayi Carboxylesterase family protein 0.0091 0.0378 0.1404
Brugia malayi hypothetical protein 0.0029 0.0055 0.0205
Brugia malayi hypothetical protein 0.0018 0.0002 0.0007

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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