Detailed information for compound 104188

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 547.537 | Formula: C26H34N3O8P
  • H donors: 2 H acceptors: 4 LogP: 3.35 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(C(=O)OCC1CCCCC1)NP(=O)(Oc1ccccc1)OCC1C=CC(O1)n1cc(C)c(=O)[nH]c1=O
  • InChi: 1S/C26H34N3O8P/c1-18-15-29(26(32)27-24(18)30)23-14-13-22(36-23)17-35-38(33,37-21-11-7-4-8-12-21)28-19(2)25(31)34-16-20-9-5-3-6-10-20/h4,7-8,11-15,19-20,22-23H,3,5-6,9-10,16-17H2,1-2H3,(H,28,33)(H,27,30,32)
  • InChiKey: VHTAYTZROSRPLR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0019 0.0011 0.002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0038 0.004 0.0151
Schistosoma mansoni P2X receptor subunit 0.0119 0.0164 0.0306
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0032 0.003 0.0056
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0012 0 0.0001
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0614 0.0918 0.1713
Schistosoma mansoni zinc binding dehydrogenase 0.0216 0.0311 0.058
Loa Loa (eye worm) ctsf protein 0.0021 0.0013 0.0015
Plasmodium vivax thioredoxin reductase, putative 0.0077 0.0099 0.0185
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0026 0.0021 0.0039
Schistosoma mansoni tyrosine kinase 0.0074 0.0095 0.0177
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.005 0.0058 0.0108
Leishmania major trypanothione reductase 0.0077 0.0099 0.0413
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0035 0.0035 0.0035
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0051 0.0057
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0095 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0038 0.004 0.0074
Onchocerca volvulus 0.0331 0.0487 0.0511
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0021 0.0013 0.0015
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0051 0.006 0.006
Brugia malayi polk-prov protein 0.0017 0.0007 0.0007
Schistosoma mansoni protein kinase 0.0016 0.0006 0.0011
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0074 0.0095 0.0095
Onchocerca volvulus 0.0044 0.0049 0.0051
Brugia malayi ecdysteroid receptor 0.0067 0.0084 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.1808 0.2738 0.3091
Brugia malayi ORL1-like opioid receptor 0.0049 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0051 0.0059 0.0111
Brugia malayi putative neuropeptide receptor 0.0049 0.0057 0.0057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0051 0.0095
Schistosoma mansoni lipoxygenase 0.0137 0.0191 0.0357
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.3678 0.5587 0.7093
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0062 0.0076 0.0096
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0057 0.007 0.013
Echinococcus multilocularis carboxylesterase 5A 0.0031 0.0029 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0039
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0035 0.0035 0.0065
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.1584 0.2397 0.4472
Onchocerca volvulus 0.0044 0.0049 0.0051
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Onchocerca volvulus 0.0095 0.0127 0.0133
Brugia malayi excitatory GABA receptor EXP-1A 0.0095 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0056 0.0068 0.0077
Schistosoma mansoni acyl carrier protein 0.0351 0.0517 0.0964
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0018 0.001 0.0018
Trichomonas vaginalis glutathione reductase, putative 0.0038 0.004 0.0074
Trypanosoma cruzi oxidoreductase, putative 0.0216 0.0311 0.1297
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0709 0.1062 0.19
Brugia malayi Egg laying defective protein 4 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0095 0.0127 0.0133
Loa Loa (eye worm) hypothetical protein 0.0014 0.0004 0.0004
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0016 0.0006 0.0006
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.3528 0.5359 0.6049
Loa Loa (eye worm) von Willebrand factor domain-containing protein 0.0044 0.0049 0.0055
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.002 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0212 0.0305 0.0344
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0092 0.0122 0.0138
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.023 0.0333 0.0375
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0049 0.0057 0.0064
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.01 0.0134 0.017
Schistosoma mansoni hypothetical protein 0.0116 0.0159 0.0298
Echinococcus granulosus hypothetical protein 0.007 0.0088 0.0165
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0067 0.0084 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Echinococcus granulosus hyperpolarization activated cyclic 0.0022 0.0016 0.0029
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0028 0.0025 0.0025
Echinococcus granulosus geminin 0.0468 0.0696 0.1299
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0032
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.002 0.0012 0.0022
Mycobacterium leprae Polyketide synthase Pks13 0.5181 0.7877 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0067 0.0084 0.0084
Onchocerca volvulus Protein ultraspiracle homolog 0.0067 0.0084 0.0088
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.023 0.0332 0.0619
Echinococcus granulosus survival motor neuron protein 1 0.0127 0.0176 0.0328
Echinococcus granulosus fmrfamide receptor 0.0049 0.0057 0.0106
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.007 0.0088 0.0164
Loa Loa (eye worm) hypothetical protein 0.0331 0.0487 0.0549
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.2783 0.4224 0.5362
Echinococcus multilocularis aldo keto reductase 0.007 0.0088 0.0165
Leishmania major d-xylulose reductase, putative 0.0216 0.0311 0.1297
Plasmodium falciparum plasmepsin VI 0.005 0.0058 0.0108
Schistosoma mansoni rab6-interacting 0.0029 0.0026 0.0048
Loa Loa (eye worm) LGC-31 protein 0.0095 0.0127 0.0143
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.0004
Brugia malayi Zona pellucida-like domain containing protein 0.0044 0.0049 0.0049
Onchocerca volvulus Cathepsin L homolog 0.0021 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0038 0.004 0.0045
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0095 0.0127 0.0236
Echinococcus multilocularis glutamate receptor 4 0.0089 0.0118 0.022
Toxoplasma gondii type I fatty acid synthase, putative 0.3678 0.5587 1
Loa Loa (eye worm) hypothetical protein 0.0533 0.0794 0.0897
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0044 0.0049 0.0055
Brugia malayi larval opioid receptor 0.0049 0.0057 0.0057
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.002 0.0013 0.0024
Mycobacterium ulcerans aldehyde dehydrogenase 0.0033 0.0032 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Trypanosoma cruzi major cysteine proteinase, putative 0.0062 0.0076 0.0316
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0057 0.0106
Echinococcus granulosus 7tm_1 domain containing protein 0.0049 0.0057 0.0106
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0095 0.0127 0.0143
Brugia malayi Heterochromatin protein 1 0.0029 0.0027 0.0027
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0066 0.0082 0.0104
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0872 0.1311 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0095 0.0127 0.0236
Trypanosoma brucei Aminopeptidase M1, putative 0.0018 0.001 0.004
Brugia malayi Dopamine receptor 0.0049 0.0057 0.0057
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0057 0.0106
Mycobacterium ulcerans Type I modular polyketide synthase 0.3462 0.5258 0.6675
Brugia malayi cathepsin L-like precursor 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Leishmania major zinc-binding dehydrogenase-like protein 0.0216 0.0311 0.1297
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0533 0.0794 0.1008
Loa Loa (eye worm) oxidoreductase 0.007 0.0088 0.01
Plasmodium vivax farnesyltransferase beta subunit, putative 0.1584 0.2397 0.4472
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0021 0.0013 0.0025
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0018 0.001 0.0018
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0049 0.0057 0.0106
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0051 0.0095
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0095 0.0127 0.0143
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0351 0.0517 0.0517
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Echinococcus granulosus nuclear factor of activated T cells 5 0.004 0.0042 0.0079
Brugia malayi von Willebrand factor type A domain containing protein 0.0044 0.0049 0.0049
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0081 0.0106 0.012
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.003 0.0056
Brugia malayi putative neuropeptide receptor NPR1 0.0049 0.0057 0.0057
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0709 0.1062 0.4431
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0013 0.0002 0.0004
Echinococcus granulosus p2X purinoceptor 4 0.0119 0.0164 0.0306
Onchocerca volvulus 0.0044 0.0049 0.0051
Echinococcus granulosus tyrosine protein kinase shark 0.0077 0.01 0.0186
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Brugia malayi hypothetical protein 0.0118 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.004
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Mycobacterium leprae conserved hypothetical protein 0.0351 0.0517 0.0656
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0092 0.0122 0.0228
Plasmodium vivax malate dehydrogenase, putative 0.0025 0.0021 0.0038
Echinococcus granulosus glycine receptor subunit alpha 1 0.0095 0.0127 0.0236
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0021 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0022 0.0016 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Echinococcus granulosus receptor type guanylyl cyclase 0.0016 0.0006 0.0011
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0032 0.0059
Brugia malayi Pepsin A precursor 0.0034 0.0034 0.0034
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0383 0.0566 0.0639
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.0004
Leishmania major cathepsin L-like protease 0.0021 0.0013 0.0055
Onchocerca volvulus 0.0044 0.0049 0.0051
Loa Loa (eye worm) glutamate receptor 0.002 0.0013 0.0015
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.2845 0.4318 0.8057
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0057 0.0106
Echinococcus granulosus aldo keto reductase family 1 member B4 0.007 0.0088 0.0165
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0095 0.0127 0.0236
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0062 0.0076 0.0096
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.002 0.0012 0.0022
Loa Loa (eye worm) hypothetical protein 0.3528 0.5359 0.6049
Leishmania major cathepsin L-like protease 0.0078 0.0101 0.0422
Mycobacterium tuberculosis Probable oxidoreductase 0.0599 0.0896 0.1137
Entamoeba histolytica hypothetical protein, conserved 0.0044 0.0049 0.0091
Echinococcus granulosus neuropeptide s receptor 0.1159 0.1749 0.3263
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0035 0.0035 0.0065
Echinococcus granulosus glycine receptor subunit beta 0.0095 0.0127 0.0236
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0018 0.001 0.0018
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.004 0.0042 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Toxoplasma gondii aldose reductase, putative 0.007 0.0088 0.0158
Onchocerca volvulus 0.007 0.0088 0.0092
Toxoplasma gondii hypothetical protein 0.0081 0.0106 0.019
Schistosoma mansoni amine GPCR 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0035 0.0036 0.0066
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0057 0.0064
Loa Loa (eye worm) oxidoreductase 0.007 0.0088 0.01
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0044 0.0049 0.0203
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0044 0.0049 0.0203
Loa Loa (eye worm) peptidase family M13 containing protein 0.0056 0.0068 0.0077
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0092 0.0122 0.0228
Echinococcus granulosus integrin alpha ps 0.0442 0.0655 0.1223
Trichomonas vaginalis chromobox protein, putative 0.0018 0.0009 0.0017
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0943 0.1419 0.5921
Brugia malayi hypothetical protein 0.0331 0.0487 0.0487
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0022 0.0016 0.0029
Echinococcus granulosus acetylcholinesterase 0.0031 0.0029 0.0053
Schistosoma mansoni potassium channel beta 0.002 0.0013 0.0024
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0018 0.001 0.0018
Trypanosoma brucei Aminopeptidase M1, putative 0.0018 0.001 0.004
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0038 0.004 0.0167
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0062 0.0076 0.0096
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0076 0.0098 0.0098
Echinococcus granulosus adam 0.0066 0.0082 0.0153
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.2845 0.4318 0.4318
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0062 0.0076 0.0096
Loa Loa (eye worm) heterochromatin protein 1 0.0029 0.0027 0.003
Brugia malayi orphan nuclear receptor NR2E1 0.0032 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Mycobacterium tuberculosis Probable reductase 0.0066 0.0082 0.0104
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0049 0.0091
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0057 0.0106
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0095 0.0127 0.0236
Schistosoma mansoni alcohol dehydrogenase 0.0216 0.0311 0.058
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0216 0.0311 0.0394
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.1584 0.2397 0.2397
Trypanosoma cruzi oxidoreductase, putative 0.0216 0.0311 0.1297
Brugia malayi AMP-binding enzyme family protein 0.1068 0.161 0.161
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0062 0.0076 0.0096
Echinococcus granulosus frizzled 0.0013 0.0002 0.0004
Schistosoma mansoni alpha-1 adrenergic receptor 0.0049 0.0057 0.0106
Plasmodium falciparum thioredoxin reductase 0.0038 0.004 0.0074
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.3528 0.5359 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0095 0.0127 0.0236
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0021 0.0013 0.0015
Mycobacterium ulcerans hypothetical protein 0.0351 0.0517 0.0656
Entamoeba histolytica acyl-CoA synthetase, putative 0.0351 0.0517 0.0964
Brugia malayi Serotonin receptor 0.0296 0.0433 0.0433
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0062 0.0076 0.0096
Echinococcus granulosus alpha 1A adrenergic receptor 0.0049 0.0057 0.0106
Brugia malayi Cathepsin L-like precursor 0.0014 0.0003 0.0003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0095 0.0127 0.0236
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0051 0.0095
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Brugia malayi acetyltransferase, GNAT family protein 0.0047 0.0054 0.0054
Onchocerca volvulus 0.0216 0.0311 0.0326
Schistosoma mansoni thyroid hormone receptor 0.0067 0.0084 0.0157
Schistosoma mansoni tyrosine kinase 0.0016 0.0006 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Schistosoma mansoni aldo-keto reductase 0.007 0.0088 0.0165
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0081 0.0106 0.0106
Brugia malayi ecdysone receptor 0.0032 0.003 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.004 0.0167
Loa Loa (eye worm) steroid hormone receptor 0.0067 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0004
Echinococcus multilocularis 0.0062 0.0076 0.0142
Mycobacterium tuberculosis Probable thioesterase TesA 0.2895 0.4395 0.5579
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0053 0.0062 0.0116
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0351 0.0517 0.0656
Echinococcus multilocularis dro:myosuppressin receptor 0.0049 0.0057 0.0106
Echinococcus granulosus smoothened 0.0294 0.0431 0.0804
Onchocerca volvulus 0.0095 0.0127 0.0133
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0331 0.0487 0.0871
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0331 0.0487 0.0549
Loa Loa (eye worm) hypothetical protein 0.0331 0.0487 0.0549
Plasmodium vivax glutathione reductase, putative 0.0077 0.0099 0.0185
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0216 0.0311 0.0311
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0351 0.0517 0.0656
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.2845 0.4318 0.8057
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0016 0.002
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0035 0.0035 0.0065
Schistosoma mansoni carbonic anhydrase-related 0.0081 0.0106 0.0198
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0018 0.001 0.0018
Onchocerca volvulus 0.0016 0.0006 0.0006
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0067 0.0084 0.0157
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0013 0.0002 0.0002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.004 0.0167
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0351 0.0517 0.0517
Brugia malayi hypothetical protein 0.0034 0.0034 0.0034
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0709 0.1062 0.1982
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0007 0.003
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0299 0.0437 0.0816
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.2585 0.3922 0.7318
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0351 0.0517 0.0656
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0087 0.0162
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0044 0.0049 0.0203
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0035 0.0035 0.0065
Onchocerca volvulus 0.0032 0.003 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0084 0.0084
Leishmania major nuclear receptor binding factor-like protein 0.0216 0.0311 0.1297
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0067 0.0084 0.0095
Brugia malayi von Willebrand factor type A domain containing protein 0.0044 0.0049 0.0049
Trypanosoma brucei C-8 sterol isomerase, putative 0.0345 0.0508 0.2117
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0019 0.001 0.0019
Giardia lamblia NADH oxidase lateral transfer candidate 0.0038 0.004 0.0074
Loa Loa (eye worm) hypothetical protein 0.0219 0.0316 0.0357
Echinococcus multilocularis sex peptide receptor 0.0049 0.0057 0.0106
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0872 0.1311 0.547
Echinococcus multilocularis lactate dehydrogenase a 0.0025 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0192 0.0274 0.031
Schistosoma mansoni integrin alpha-ps 0.0442 0.0655 0.1223
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0872 0.1311 0.1664
Mycobacterium ulcerans acyl-CoA synthetase 0.0351 0.0517 0.0656
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0943 0.1419 0.5921
Echinococcus granulosus 7TM GPCR rhodopsin 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0067 0.0084 0.0095
Onchocerca volvulus 0.0021 0.0013 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0018 0.001 0.0018
Trichomonas vaginalis chromobox protein, putative 0.0018 0.0009 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0001 0.0002
Schistosoma mansoni microtubule-associated protein tau 0.0256 0.0372 0.0694
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0018 0.001 0.0018
Brugia malayi G-protein coupled receptor 0.0049 0.0057 0.0057
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0049 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0062 0.0076 0.0096
Echinococcus multilocularis neuropeptide receptor A26 0.1159 0.1749 0.3263
Brugia malayi photoreceptor-specific nuclear receptor 0.0067 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0013 0.0001 0.0002
Onchocerca volvulus 0.0049 0.0057 0.0059
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0044 0.0049 0.0049
Brugia malayi hypothetical protein 0.0044 0.0049 0.0049
Mycobacterium tuberculosis Conserved hypothetical protein 0.0351 0.0517 0.0656
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Echinococcus granulosus nAChR subunit 0.0051 0.006 0.0112
Schistosoma mansoni aldehyde dehydrogenase 0.0033 0.0032 0.0059
Echinococcus granulosus p2X purinoceptor 4 0.0119 0.0164 0.0306
Toxoplasma gondii hypothetical protein 0.0067 0.0085 0.0151
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0016 0.0029
Schistosoma mansoni nuclear receptor nhr-48 0.0032 0.003 0.0056
Mycobacterium ulcerans polyketide synthase MbtC 0.0872 0.1311 0.1664
Brugia malayi Cyclic-nucleotide gated cation channel 0.0022 0.0016 0.0016
Brugia malayi nuclear hormone receptor 0.0067 0.0084 0.0084
Echinococcus granulosus carbonic anhydrase 0.0081 0.0106 0.0198
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0023
Brugia malayi G protein-coupled receptor 0.0049 0.0057 0.0057
Schistosoma mansoni voltage-gated potassium channel 0.0103 0.0139 0.0259
Onchocerca volvulus Matrilysin homolog 0.0182 0.026 0.0272
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1808 0.2738 0.2738
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.2783 0.4224 0.5362
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0943 0.1419 0.1602
Plasmodium falciparum malate dehydrogenase 0.0025 0.0021 0.0038
Echinococcus granulosus cathepsin L cysteine proteinase 0.0021 0.0013 0.0025
Schistosoma mansoni zinc finger protein 0.0032 0.003 0.0056
Schistosoma mansoni carbonic anhydrase-related 0.0081 0.0106 0.0198
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0074 0.0095 0.0176
Trichomonas vaginalis aldo-keto reductase, putative 0.002 0.0013 0.0023
Treponema pallidum hypothetical protein 0.0044 0.0049 0.0178
Schistosoma mansoni endothelin-converting enzyme-related 0.0019 0.001 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0049 0.0056 0.0104
Schistosoma mansoni glutamate receptor kainate 0.0053 0.0063 0.0117
Onchocerca volvulus 0.0014 0.0003 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0164 0.0185
Brugia malayi hypothetical protein 0.0015 0.0005 0.0005
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0049 0.0057 0.0106
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0391 0.0578 0.1079
Onchocerca volvulus Fatty acid synthase homolog 0.6263 0.9528 1
Trypanosoma cruzi protein farnesyltransferase, putative 0.1584 0.2397 1
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0219 0.0316 0.059
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Echinococcus granulosus glutamate receptor ionotropic kainate 0.002 0.0012 0.0022
Brugia malayi Cathepsin L-like precursor 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0074 0.0095 0.0176
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0038 0.004 0.0075
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0023
Onchocerca volvulus 0.6048 0.9199 0.9655
Toxoplasma gondii lactate dehydrogenase LDH1 0.0025 0.0021 0.0037
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0508 0.0756 0.141
Mycobacterium ulcerans polyketide synthase Pks9 0.2285 0.3465 0.4398
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0219 0.0316 0.059
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0114 0.0155 0.0197
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.2496 0.3786 0.4806
Echinococcus granulosus serotonin transporter 0.1808 0.2738 0.5109
Schistosoma mansoni kinesin eg-5 0.0014 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0709 0.1062 0.1199
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Schistosoma mansoni hypothetical protein 0.0044 0.0049 0.0091
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0057 0.0106
Brugia malayi Integrin alpha pat-2 precursor 0.0442 0.0655 0.0655
Schistosoma mansoni cytochrome P450 0.0062 0.0076 0.0142
Echinococcus granulosus cGMP dependent protein kinase 1 0.0013 0.0001 0.0002
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.007 0.0088 0.0164
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0007
Onchocerca volvulus 0.0026 0.0021 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Brugia malayi Cytochrome P450 family protein 0.0114 0.0155 0.0155
Brugia malayi hypothetical protein 0.0044 0.0049 0.0049
Loa Loa (eye worm) acetyltransferase 0.0047 0.0054 0.0061
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0062 0.0076 0.0096
Loa Loa (eye worm) norepinephrine transporter 0.1808 0.2738 0.3091
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0032 0.003 0.003
Loa Loa (eye worm) thioredoxin reductase 0.0077 0.0099 0.0112
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Onchocerca volvulus Cathepsin L homolog 0.0021 0.0013 0.0014
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0943 0.1419 0.2648
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0216 0.0311 0.058
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0331 0.0487 0.0487
Schistosoma mansoni glutamate receptor kainate 0.0053 0.0063 0.0117
Brugia malayi Thioredoxin reductase 0.0077 0.0099 0.0099
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0062 0.0076 0.0096
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0117 0.0132
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.3528 0.5359 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0068 0.0085 0.0159
Brugia malayi hypothetical protein 0.0044 0.0049 0.0049
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0031 0.003 0.0055
Leishmania major zinc binding dehydrogenase-like protein 0.0216 0.0311 0.1297
Loa Loa (eye worm) hypothetical protein 0.0058 0.007 0.0079
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Plasmodium falciparum kinesin-5 0.0014 0.0003 0.0005
Onchocerca volvulus 0.0013 0.0002 0.0002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0095 0.0127 0.0127
Trypanosoma brucei cytochrome P450, putative 0.0114 0.0155 0.0647
Trypanosoma cruzi cytochrome P450, putative 0.0114 0.0155 0.0647
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.3678 0.5587 0.7093
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.1584 0.2397 0.4472
Schistosoma mansoni ATP-binding cassette transporter 0.0053 0.0063 0.0117
Echinococcus granulosus glycine receptor subunit beta 0.0095 0.0127 0.0236
Onchocerca volvulus 0.0943 0.1419 0.1489
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.3462 0.5258 0.6675
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0216 0.0311 0.0394
Brugia malayi GnHR receptor homolog 0.0049 0.0057 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0044 0.0049 0.0091
Mycobacterium tuberculosis Probable dehydrogenase 0.0066 0.0082 0.0104
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0216 0.0311 0.0351
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0018 0.001 0.004
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.1068 0.161 0.2044
Echinococcus multilocularis integrin alpha 3 0.0212 0.0305 0.0569
Echinococcus multilocularis frizzled 4 0.0013 0.0002 0.0004
Plasmodium falciparum eukaryotic initiation factor 4A 0.0035 0.0035 0.0065
Loa Loa (eye worm) runx1 0.0021 0.0014 0.0016
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0066 0.0082 0.0104
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0331 0.0487 0.0487
Loa Loa (eye worm) hypothetical protein 0.0533 0.0794 0.0897
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0013 0.0002 0.0004
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0094 0.0125 0.0158
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0095 0.0126 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0057 0.0106
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0331 0.0487 0.0908
Trypanosoma cruzi acyl transferase-like protein 0.0219 0.0316 0.1319
Loa Loa (eye worm) hypothetical protein 0.0025 0.0021 0.0023
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.3528 0.5359 1
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.023 0.0332 0.0619
Echinococcus granulosus lactate dehydrogenase a 0.0025 0.0021 0.0039
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0219 0.0316 0.059
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0331 0.0487 0.0908
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0062 0.0076 0.0096
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Echinococcus multilocularis conserved hypothetical protein 0.0371 0.0547 0.1021
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.0101 0.0422
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0709 0.1062 0.1981
Schistosoma mansoni hypothetical protein 0.0049 0.0057 0.0106
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0044 0.0049 0.0092
Brugia malayi Cation transporter family protein 0.0095 0.0127 0.0127
Entamoeba histolytica protein kinase, putative 0.0018 0.001 0.0018
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0351 0.0517 0.0583
Loa Loa (eye worm) hypothetical protein 0.0056 0.0068 0.0077
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0033 0.0032 0.0059
Loa Loa (eye worm) hypothetical protein 0.0087 0.0115 0.0129
Entamoeba histolytica malate dehydrogenase, putative 0.0025 0.0021 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0057 0.0106
Brugia malayi Calcitonin receptor-like protein seb-1 0.0145 0.0203 0.0203
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0013 0.0002 0.0004
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.3678 0.5587 0.7093
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0095 0.0127 0.0127
Onchocerca volvulus 0.0118 0.0162 0.017
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Toxoplasma gondii aldo-keto reductase 0.002 0.0013 0.0022
Brugia malayi latrophilin 2 splice variant baaae 0.0099 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Trypanosoma brucei protein kinase, putative 0.0044 0.0049 0.0203
Schistosoma mansoni steroid hormone receptor ad4bp 0.0067 0.0084 0.0157
Treponema pallidum 76K protein 0.0044 0.0049 0.0178
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0044 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0067 0.0084 0.0095
Echinococcus multilocularis tyrosine kinase 0.0016 0.0006 0.0011
Echinococcus granulosus potassium voltage gated channel protein 0.0046 0.0052 0.0097
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0035 0.0036 0.0067
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0062 0.0076 0.0096
Brugia malayi Cell death protein 3 precursor 0.0118 0.0162 0.0162
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0033 0.0032 0.0059
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0095 0.0127 0.0127
Trypanosoma cruzi trypanothione reductase, putative 0.0077 0.0099 0.0413
Onchocerca volvulus 0.3246 0.4929 0.5174
Onchocerca volvulus 0.0034 0.0034 0.0035
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0016 0.0029
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Onchocerca volvulus 0.0095 0.0127 0.0133
Schistosoma mansoni polycystin 1-related 0.0029 0.0026 0.0048
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0033 0.0032 0.0032
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0038 0.004 0.0075
Onchocerca volvulus 0.0391 0.0578 0.0607
Plasmodium falciparum aldehyde reductase, putative 0.002 0.0013 0.0023
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0057 0.0106
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.2254 0.3417 0.6116
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0793 0.1191 0.1512
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0943 0.1419 0.5921
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.007 0.0088 0.0112
Echinococcus granulosus sodium and chloride dependent glycine 0.0383 0.0566 0.1056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0021 0.0013 0.0025
Schistosoma mansoni nuclear hormone receptor 0.0032 0.003 0.0056
Mycobacterium leprae Conserved hypothetical protein 0.005 0.0057 0.0073
Echinococcus granulosus FTZ F1 alpha 0.0067 0.0084 0.0157
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0745 0.1118 0.1262
Leishmania major cathepsin L-like protease 0.0021 0.0013 0.0055
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Schistosoma mansoni metabotropic glutamate receptor 0.0179 0.0254 0.0474
Schistosoma mansoni cellular tumor antigen P53 0.0014 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0067 0.0085 0.0095
Schistosoma mansoni cathepsin F (C01 family) 0.0021 0.0013 0.0025
Schistosoma mansoni [ACP] S-malonyltransferase 0.0219 0.0316 0.059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Echinococcus granulosus protein farnesyltransferase subunit beta 0.1584 0.2397 0.4472
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0035 0.0035 0.0062
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0032 0.0059
Leishmania major cathepsin L-like protease 0.0078 0.0101 0.0422
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.0084 0.0084
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0067 0.0084 0.0088
Echinococcus multilocularis expressed conserved protein 0.0013 0.0001 0.0002
Onchocerca volvulus Matrix metalloproteinase homolog 0.0182 0.026 0.0272
Onchocerca volvulus 0.0051 0.006 0.0063
Loa Loa (eye worm) hypothetical protein 0.0067 0.0084 0.0095
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0067 0.0084 0.0157
Plasmodium vivax aspartyl protease, putative 0.0034 0.0034 0.0062
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Leishmania major C-8 sterol isomerase-like protein 0.0345 0.0508 0.2117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Echinococcus granulosus glutamate receptor 2 0.0137 0.0191 0.0357
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0216 0.0311 0.0394
Schistosoma mansoni glutamate receptor kainate 0.0053 0.0063 0.0117
Schistosoma mansoni neurotransmitter gated ion channel 0.0044 0.0049 0.0091
Onchocerca volvulus Huntingtin homolog 0.0087 0.0115 0.012
Brugia malayi metabotropic glutamate receptor type 2 0.0035 0.0036 0.0036
Brugia malayi Doublecortin family protein 0.0029 0.0026 0.0026
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0095 0.0127 0.0127
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0016 0.0029
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0016 0.0064
Echinococcus granulosus aldo keto reductase family 1 member B4 0.007 0.0088 0.0165
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0018 0.001 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.0021 0.0013 0.0055
Plasmodium falciparum plasmepsin IX 0.0034 0.0034 0.0062
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0068
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0068 0.0085 0.0159
Brugia malayi Phosphopantetheine attachment site family protein 0.0351 0.0517 0.0517
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0872 0.1311 0.148
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0007 0.003
Leishmania major aldo-keto reductase-like protein 0.007 0.0088 0.0367
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0246 0.0357 0.1489
Trichomonas vaginalis glucosylceramidase, putative 0.0074 0.0095 0.0176
Schistosoma mansoni hypothetical protein 0.0351 0.0517 0.0964
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0095 0.0126 0.0143
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0049 0.0057 0.0106
Plasmodium vivax aspartyl protease, putative 0.0034 0.0034 0.0062
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Onchocerca volvulus 0.0049 0.0057 0.0059
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Trypanosoma brucei trypanothione reductase 0.0077 0.0099 0.0413
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Plasmodium falciparum geranylgeranyltransferase, putative 0.0709 0.1062 0.1981
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0033 0.0032 0.0059
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0351 0.0517 0.2156
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0216 0.0311 0.0394
Brugia malayi hypothetical protein 0.0044 0.0049 0.0049
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.1182 0.1783 0.2264
Schistosoma mansoni loxhd1 0.0029 0.0026 0.0048
Echinococcus multilocularis NMDA receptor 0.002 0.0012 0.0022
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0057 0.0106
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.002 0.0012 0.0023
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0057 0.0106
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0032 0.0059
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.004 0.0042 0.0042
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0216 0.0311 0.058
Brugia malayi lactate dehydrogenase. 0.0025 0.0021 0.0021
Echinococcus granulosus allatostatin A receptor 0.0049 0.0057 0.0106
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.1584 0.2397 0.4472
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0046 0.0052 0.0052
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0057 0.0106
Onchocerca volvulus 0.0049 0.0057 0.0059
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.2845 0.4318 0.4874
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Loa Loa (eye worm) AMP-binding enzyme family protein 0.3246 0.4929 0.5564
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0057 0.0106
Brugia malayi Serine carboxypeptidase S28 family protein 0.0032 0.003 0.003
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0943 0.1419 0.1419
Entamoeba histolytica hypothetical protein 0.0044 0.0049 0.0091
Schistosoma mansoni amine GPCR 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0943 0.1419 0.2648
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0216 0.0311 0.0394
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0012 0 0.0001
Echinococcus multilocularis integrin alpha ps 0.0442 0.0655 0.1223
Echinococcus multilocularis frizzled 10 0.0013 0.0002 0.0004
Schistosoma mansoni malate dehydrogenase 0.0025 0.0021 0.0039
Schistosoma mansoni hypothetical protein 0.0049 0.0057 0.0106
Brugia malayi hypothetical protein 0.0087 0.0115 0.0115
Toxoplasma gondii NADPH-glutathione reductase 0.0038 0.004 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0709 0.1062 0.4431
Plasmodium vivax geranylgeranyltransferase, putative 0.0709 0.1062 0.1981
Plasmodium vivax thrombospondin-related anonymous protein 0.0044 0.0049 0.0091
Schistosoma mansoni pol-related 0.007 0.0088 0.0165
Schistosoma mansoni hypothetical protein 0.0044 0.0049 0.0091
Schistosoma mansoni voltage-gated cation channel 0.0033 0.0032 0.0059
Loa Loa (eye worm) hypothetical protein 0.0391 0.0578 0.0653
Loa Loa (eye worm) glutathione reductase 0.0077 0.0099 0.0112
Schistosoma mansoni transcription factor LCR-F1 0.0013 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0023
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0027 0.0023 0.0043
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0018 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Plasmodium vivax dynein-related AAA-type ATPase, putative 0.0044 0.0049 0.0091
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0391 0.0578 0.1079
Loa Loa (eye worm) hypothetical protein 0.0127 0.0176 0.0198
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0216 0.0311 0.1297
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0049 0.0057 0.0106
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0051 0.0051
Schistosoma mansoni protein farnesyltransferase subunit beta 0.1584 0.2397 0.4472
Loa Loa (eye worm) glutamate receptor 0.0023 0.0017 0.002
Echinococcus granulosus kinesin family 1 0.0104 0.0141 0.0263
Echinococcus granulosus disintegrin and metalloproteinase 0.0138 0.0192 0.0359
Plasmodium vivax vivapain-2 0.0021 0.0013 0.0025
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0057 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0005
Schistosoma mansoni growth hormone secretagogue receptor 0.0049 0.0057 0.0106
Trypanosoma brucei protein farnesyltransferase beta subunit 0.1584 0.2397 1
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0074 0.0095 0.0107
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0095 0.0127 0.0127
Echinococcus granulosus peptide allatostatin:somatostatin 0.0049 0.0057 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Brugia malayi Matrixin family protein 0.0082 0.0107 0.0107
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0018 0.001 0.004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0038 0.004 0.0151
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0216 0.0311 0.1297
Echinococcus granulosus L lactate dehydrogenase 0.0015 0.0006 0.0011
Brugia malayi hypothetical protein 0.0013 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0018 0.001 0.0018
Plasmodium vivax acyl carrier protein, putative 0.0351 0.0517 0.0964
Giardia lamblia Rab geranylgeranyltransferase 0.0709 0.1062 0.1981
Trichomonas vaginalis aldo/keto reductase, putative 0.007 0.0088 0.0164
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0019 0.001 0.0019
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0219 0.0316 0.0316
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.0004
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0057 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0057 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0067 0.0084 0.0084
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) peptidase family M13 containing protein 0.0056 0.0068 0.0077
Trichomonas vaginalis mercuric reductase, putative 0.0038 0.004 0.0074
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Loa Loa (eye worm) hypothetical protein 0.0216 0.0311 0.0351
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0032 0.003 0.0056
Schistosoma mansoni neprilysin-2 (M13 family) 0.0039 0.0041 0.0076
Schistosoma mansoni hypothetical protein 0.0062 0.0076 0.0142
Loa Loa (eye worm) matrixin family protein 0.0199 0.0285 0.0321
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.2829 0.4294 0.545
Brugia malayi ADAM-TS Spacer 1 family protein 0.0028 0.0025 0.0025
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.004 0.0167
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0044 0.0049 0.0091
Echinococcus granulosus carbonic anhydrase II 0.0246 0.0357 0.0666
Brugia malayi p70 ribosomal S6 kinase beta 0.0018 0.0009 0.0009
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0019 0.001 0.0019
Echinococcus multilocularis glycine receptor subunit beta 0.0095 0.0127 0.0236
Onchocerca volvulus 0.0051 0.006 0.0063
Echinococcus granulosus aldo keto reductase family 1 member B4 0.007 0.0088 0.0165
Trypanosoma cruzi lanosterol synthase, putative 0.0793 0.1191 0.497
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0872 0.1311 0.2346
Echinococcus granulosus orexin receptor type 2 0.0049 0.0057 0.0106
Brugia malayi Angiotensin-converting enzyme family protein 0.0251 0.0364 0.0364
Schistosoma mansoni nAChR subunit 0.0095 0.0127 0.0236
Echinococcus granulosus g-protein coupled receptor 0.0049 0.0057 0.0106
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0216 0.0311 0.0394
Loa Loa (eye worm) hypothetical protein 0.0082 0.0107 0.0121
Schistosoma mansoni neuropeptide f receptor 76f 0.0049 0.0057 0.0106
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0046 0.0052 0.0097
Plasmodium falciparum circumsporozoite- and TRAP-related protein 0.0044 0.0049 0.0091
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0038 0.004 0.0074
Onchocerca volvulus 0.0067 0.0084 0.0088
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0018 0.0009 0.0016
Plasmodium falciparum plasmepsin VIII, putative 0.0034 0.0034 0.0062
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0095 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.0046 0.0052 0.0097
Echinococcus multilocularis endothelin converting enzyme 1 0.0076 0.0098 0.0184
Loa Loa (eye worm) matrix metalloproteinase 0.0082 0.0107 0.0121
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0016 0.002
Schistosoma mansoni opsin-like receptor 0.0049 0.0057 0.0106
Brugia malayi tailless protein 0.0032 0.003 0.003
Echinococcus multilocularis inhibitor of apoptosis protein 0.0391 0.0578 0.1079
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0331 0.0487 0.0908
Echinococcus granulosus frizzled 5 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Toxoplasma gondii peptidase family M13 protein 0.0076 0.0098 0.0176
Loa Loa (eye worm) glutamate receptor 1 0.0142 0.0198 0.0224
Loa Loa (eye worm) hypothetical protein 0.0067 0.0084 0.0095
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.023 0.0332 0.0619
Schistosoma mansoni nAChR subunit 0.0095 0.0127 0.0236
Brugia malayi Protein kinase domain containing protein 0.0069 0.0087 0.0087
Brugia malayi nuclear hormone receptor family member odr-7 0.0032 0.003 0.003
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0003 0.0005
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0216 0.0311 0.0394
Brugia malayi Immunoglobulin I-set domain containing protein 0.0044 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0351 0.0517 0.0964
Mycobacterium tuberculosis Conserved protein 0.1047 0.1577 0.2002
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0709 0.1062 0.19
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0062 0.0076 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Giardia lamblia Histone acetyltransferase GCN5 0.0013 0.0001 0.0002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0145 0.0203 0.038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0021 0.0013 0.0025
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0052 0.0096
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0137 0.0191 0.0357
Schistosoma mansoni amine GPCR 0.0326 0.0478 0.0892
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Trypanosoma cruzi cruzipain precursor, putative 0.0078 0.0101 0.0422
Loa Loa (eye worm) doublecortin family protein 0.0029 0.0026 0.0029
Loa Loa (eye worm) hypothetical protein 0.0053 0.0062 0.007
Trichomonas vaginalis chromobox protein, putative 0.0029 0.0027 0.005
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0095 0.0127 0.0127
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0017 0.0007 0.0007
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0038 0.0041 0.0075
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0872 0.1311 0.2446
Entamoeba histolytica protein kinase, putative 0.0018 0.001 0.0018
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0095 0.0127 0.0236
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0351 0.0517 0.0656
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0074 0.0095 0.0178
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0057 0.0106
Onchocerca volvulus Cell death protein 3 homolog 0.0118 0.0162 0.017
Mycobacterium ulcerans oxidoreductase 0.007 0.0088 0.0112
Loa Loa (eye worm) hypothetical protein 0.1808 0.2738 0.3091
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0013 0.0002 0.0002
Echinococcus granulosus nmda type glutamate receptor 0.0015 0.0005 0.0009
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0023 0.0017 0.002
Trypanosoma brucei hypothetical protein, conserved 0.0943 0.1419 0.5921
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0216 0.0311 0.058
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Brugia malayi Peptidase family M13 containing protein 0.0076 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0067 0.0084 0.0095
Loa Loa (eye worm) hypothetical protein 0.0383 0.0566 0.0639
Onchocerca volvulus 0.0049 0.0057 0.0059
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.2845 0.4318 0.8057
Schistosoma mansoni L-lactate dehydrogenase 0.0025 0.0021 0.0039
Loa Loa (eye worm) phosphatidylinositol 3 0.0066 0.0083 0.0094
Echinococcus granulosus chromobox protein 1 0.0029 0.0027 0.005
Trypanosoma brucei rac serine-threonine kinase, putative 0.0018 0.001 0.0041
Loa Loa (eye worm) hypothetical protein 0.0216 0.0311 0.0351
Trypanosoma brucei acyl transferase-like protein 0.0219 0.0316 0.1319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0038 0.004 0.0051
Schistosoma mansoni nuclear hormone receptor 0.0032 0.003 0.0056
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0044 0.0049 0.0091
Echinococcus multilocularis apoptotic protease activating factor 1 0.0118 0.0162 0.0302
Onchocerca volvulus 0.007 0.0088 0.0092
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0044 0.0049 0.0055
Trypanosoma cruzi extracellular receptor, putative 0.0015 0.0005 0.0019
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.005 0.0058 0.0103
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0018 0.001 0.0018
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0533 0.0794 0.1008
Echinococcus granulosus aminopeptidase N 0.0018 0.001 0.0018
Loa Loa (eye worm) cytochrome P450 family protein 0.0114 0.0155 0.0175
Echinococcus granulosus thyroid hormone receptor alpha 0.0032 0.003 0.0056
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Brugia malayi Cathepsin L-like precursor 0.0021 0.0013 0.0013
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0331 0.0487 0.0549
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Mycobacterium ulcerans short chain dehydrogenase 0.0599 0.0896 0.1137
Entamoeba histolytica aldose reductase, putative 0.007 0.0088 0.0164
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0021 0.0013 0.0025
Loa Loa (eye worm) cytochrome P450 family protein 0.0114 0.0155 0.0175
Trypanosoma cruzi Aminopeptidase M1, putative 0.0018 0.001 0.004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Schistosoma mansoni [ACP] S-malonyltransferase 0.0219 0.0316 0.059
Schistosoma mansoni P2X receptor subunit 0.0119 0.0164 0.0306
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0062 0.0076 0.0096
Mycobacterium ulcerans oxidoreductase 0.0216 0.0311 0.0394
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.3462 0.5258 0.6675
Mycobacterium tuberculosis Probable oxidoreductase 0.0094 0.0125 0.0158
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0051 0.0095
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0044 0.0049 0.0203
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0032 0.003 0.0056
Echinococcus granulosus GPCR family 2 0.0046 0.0052 0.0097
Brugia malayi Metabotropic glutamate receptor precursor. 0.0023 0.0017 0.0017
Echinococcus granulosus neuropeptide receptor A26 0.1159 0.1749 0.3263
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0053 0.0062 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0001 0.0002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0049 0.0057 0.0064
Mycobacterium tuberculosis Polyketide synthase Pks2 0.3368 0.5115 0.6493
Echinococcus multilocularis integrin beta 2 0.0894 0.1345 0.251
Brugia malayi nuclear hormone receptor family member nhr-6 0.0032 0.003 0.003
Echinococcus granulosus dro:myosuppressin receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0047 0.0054 0.01
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.007 0.0088 0.0088
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0053 0.0063 0.0117
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0044 0.0049 0.0091
Mycobacterium ulcerans thioesterase TesA 0.2895 0.4395 0.5579
Mycobacterium ulcerans oxidoreductase FadB5 0.0216 0.0311 0.0394
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.003 0.0031
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0049 0.0057 0.0106
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.0084 0.0157
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0049 0.0049
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0039 0.0041 0.0076
Trichomonas vaginalis aldo-keto reductase, putative 0.002 0.0013 0.0023
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0049 0.0057 0.0064
Toxoplasma gondii hypothetical protein 0.0331 0.0487 0.0871
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0039 0.0041 0.0076
Mycobacterium ulcerans acyl carrier protein 0.0351 0.0517 0.0656
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Toxoplasma gondii AGC kinase 0.0018 0.0009 0.0016
Echinococcus multilocularis glutamate receptor 2 0.0142 0.0198 0.037
Echinococcus granulosus cathepsin l cysteine peptidase 0.0021 0.0013 0.0025
Plasmodium falciparum amino acid transporter, putative 0.0331 0.0487 0.0908
Echinococcus granulosus glutamate NMDA receptor subunit 0.0053 0.0063 0.0117
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0331 0.0487 0.0908
Echinococcus granulosus glycine receptor subunit alpha 1 0.0095 0.0127 0.0236
Echinococcus multilocularis kinesin family 1 0.0104 0.0141 0.0263
Trypanosoma brucei oxidoreductase, putative 0.0216 0.0311 0.1297
Loa Loa (eye worm) hypothetical protein 0.0056 0.0068 0.0077
Brugia malayi hypothetical protein 0.0044 0.0049 0.0049
Schistosoma mansoni voltage-gated potassium channel 0.0103 0.0139 0.0259
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0019 0.001 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0049 0.0056 0.0104
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0029
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0533 0.0794 0.1008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.0084 0.0157
Brugia malayi Cytochrome P450 family protein 0.0114 0.0155 0.0155
Echinococcus multilocularis allatostatin A receptor 0.0049 0.0057 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Echinococcus multilocularis ecdysone induced protein 78C 0.0067 0.0084 0.0157
Loa Loa (eye worm) aspartyl protease 6 0.0034 0.0034 0.0038
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Schistosoma mansoni aldehyde dehydrogenase 0.0033 0.0032 0.0059
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.2845 0.4318 0.8057
Brugia malayi hypothetical protein 0.0032 0.003 0.003
Schistosoma mansoni neuropeptide receptor 0.0049 0.0057 0.0106
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0351 0.0517 0.0656
Echinococcus granulosus ecdysone induced protein 78C 0.0067 0.0084 0.0157
Loa Loa (eye worm) calcium channel 0.0033 0.0032 0.0036
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0038 0.004 0.0051
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0062 0.0076 0.0096
Schistosoma mansoni sodium/chloride dependent transporter 0.1808 0.2738 0.5109
Brugia malayi sulfakinin receptor protein 0.0049 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0082 0.0107 0.0121
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0062 0.0076 0.0316
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0057 0.0106
Mycobacterium tuberculosis Hypothetical protein 0.1047 0.1577 0.2002
Brugia malayi Glutamate receptor 2 precursor 0.0142 0.0198 0.0198
Echinococcus multilocularis receptor type guanylyl cyclase 0.0016 0.0006 0.0011
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0035 0.0036 0.0067
Loa Loa (eye worm) hypothetical protein 0.0089 0.0118 0.0133
Treponema pallidum ATP-dependent RNA helicase 0.0035 0.0035 0.0127
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.1584 0.2397 0.4472
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0044 0.0049 0.0091
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0094 0.0126 0.0235
Echinococcus multilocularis adam 0.0066 0.0082 0.0153
Echinococcus granulosus caspase 2 0.0118 0.0162 0.0302
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0044 0.0049 0.0049
Loa Loa (eye worm) integrin beta-2 0.1221 0.1844 0.2081
Loa Loa (eye worm) hypothetical protein 0.0709 0.1062 0.1199
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0111
Schistosoma mansoni neuropeptide receptor 0.0049 0.0057 0.0106
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0026 0.0021 0.0021
Leishmania major oxidoreductase-like protein 0.0216 0.0311 0.1297
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0251 0.0364 0.0411
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.3462 0.5258 0.6675
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0872 0.1311 1
Leishmania major oxidoreductase, putative 0.0216 0.0311 0.1297
Echinococcus granulosus microtubule associated protein 2 0.0256 0.0372 0.0694
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0081 0.0106 0.0106
Echinococcus multilocularis p2X purinoceptor 4 0.0119 0.0164 0.0306
Echinococcus multilocularis integrin alpha ps 0.0442 0.0655 0.1223
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.1584 0.2397 0.2705
Entamoeba histolytica acetyltransferase, GNAT family 0.0013 0.0001 0.0002
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0049 0.0057 0.0106
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.002 0.0013 0.0022
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0216 0.0311 0.0394
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0057 0.0106
Onchocerca volvulus 0.002 0.0013 0.0013
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0044 0.0049 0.0049
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.004 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0021 0.0013 0.0025
Echinococcus granulosus aldo keto reductase family 1 member B4 0.007 0.0088 0.0165
Schistosoma mansoni frizzled-like receptor 0.0013 0.0002 0.0004
Brugia malayi Cathepsin L-like precursor 0.0021 0.0013 0.0013
Echinococcus multilocularis carbonic anhydrase 0.0081 0.0106 0.0198
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0331 0.0487 0.0908
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0164 0.0185
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0216 0.0311 0.058
Trypanosoma brucei oxidoreductase, putative 0.0216 0.0311 0.1297
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0006 0.0007
Mycobacterium ulcerans dehydrogenase 0.0216 0.0311 0.0394
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0216 0.0311 0.0394
Trichomonas vaginalis CMGC family protein kinase 0.0044 0.0049 0.0091
Plasmodium falciparum plasmepsin III 0.0034 0.0034 0.0062
Leishmania major cathepsin L-like protease 0.0021 0.0013 0.0055
Onchocerca volvulus 0.0049 0.0057 0.0059
Entamoeba histolytica alcohol dehydrogenase, putative 0.002 0.0013 0.0023
Echinococcus granulosus integrin alpha ps 0.0212 0.0305 0.0569
Echinococcus multilocularis AMP dependent ligase 0.0351 0.0517 0.0964
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0044 0.0049 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0049 0.0091
Brugia malayi G-protein coupled receptor 0.0049 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0067 0.0084 0.0084
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0013 0.0002 0.0003
Loa Loa (eye worm) acyl carrier protein 0.1598 0.2417 0.2728
Echinococcus multilocularis aminopeptidase N 0.0018 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Echinococcus multilocularis aldehyde reductase 0.005 0.0057 0.0107
Plasmodium falciparum cysteine proteinase falcipain 3 0.0021 0.0013 0.0025
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0951 0.1431 0.267
Schistosoma mansoni opsin-like receptor 0.0049 0.0057 0.0106
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0035 0.0035 0.0044
Loa Loa (eye worm) carbonic anhydrase 3 0.0246 0.0357 0.0403
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.003 0.0056
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Schistosoma mansoni neprilysin 0.002 0.0012 0.0023
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Schistosoma mansoni nAChR subunit 0.0095 0.0127 0.0236
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.004 0.0167
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0876 0.1317 0.2456
Mycobacterium leprae Conserved hypothetical protein 0.0062 0.0076 0.0096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.004 0.0167
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0351 0.0517 0.0656
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0067 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Echinococcus granulosus integrin beta 2 0.0894 0.1345 0.251
Brugia malayi Cation transporter family protein 0.0095 0.0127 0.0127
Schistosoma mansoni carbonic anhydrase 0.0081 0.0106 0.0198
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0872 0.1311 0.2447
Brugia malayi neuropeptide F receptor 0.0049 0.0057 0.0057
Schistosoma mansoni sodium/chloride dependent transporter 0.0383 0.0566 0.1056
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0031 0.0029 0.0053
Echinococcus granulosus g protein coupled receptor 0.0049 0.0057 0.0106
Echinococcus multilocularis G protein coupled receptor 139 0.0049 0.0057 0.0106
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.004 0.0167
Brugia malayi Matrixin family protein 0.0082 0.0107 0.0107
Echinococcus granulosus sodium and chloride dependent glycine 0.0383 0.0566 0.1056
Echinococcus multilocularis neuropeptide FF receptor 2 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.002 0.0013 0.0023
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0331 0.0487 0.0487
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.3368 0.5115 0.6493
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0943 0.1419 0.2648
Echinococcus granulosus AMP dependent ligase 0.0351 0.0517 0.0964
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.0084 0.0084
Echinococcus multilocularis mitogen activated protein kinase 3 0.0044 0.0049 0.0091
Mycobacterium leprae Probable polyketide synthase Pks1 0.3678 0.5587 0.7093
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0216 0.0311 0.0394
Onchocerca volvulus Matrilysin homolog 0.0082 0.0107 0.0112
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.1584 0.2397 0.4472
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0039 0.0041 0.0076
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0021 0.0021
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0066 0.0082 0.0153
Echinococcus granulosus RUN 0.0029 0.0026 0.0048
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0049 0.0057 0.0106
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0022 0.0016 0.0029
Plasmodium vivax lactate dehydrogenase 0.0025 0.0021 0.0038
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0057 0.0064
Plasmodium vivax aspartyl proteinase, putative 0.005 0.0058 0.0108
Plasmodium falciparum aldo-keto reductase, putative 0.002 0.0013 0.0023
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Echinococcus multilocularis glycine receptor subunit beta 0.0095 0.0127 0.0236
Loa Loa (eye worm) hypothetical protein 0.0087 0.0115 0.0129
Leishmania major carbonic anhydrase-like protein 0.0246 0.0357 0.1489
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.3528 0.5359 0.5359
Echinococcus granulosus lipoxygenase domain containing protein 0.0029 0.0026 0.0048
Echinococcus granulosus aldo keto reductase family 1 member B4 0.007 0.0088 0.0165
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0351 0.0517 0.2156
Toxoplasma gondii aspartyl protease ASP3 0.0034 0.0034 0.006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.3678 0.5587 0.7093
Schistosoma mansoni metabotropic glutamate receptor 0.0015 0.0005 0.0009
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0062 0.0076 0.0096
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.0101 0.0422
Brugia malayi Pre-SET motif family protein 0.0367 0.0541 0.0541
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0068 0.0085 0.0159
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Schistosoma mansoni neuropeptide receptor 0.0049 0.0057 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0021 0.0013 0.0025
Mycobacterium leprae probable zinc metalloprotease 0.0076 0.0098 0.0125
Loa Loa (eye worm) hypothetical protein 0.1934 0.293 0.3307
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Loa Loa (eye worm) ACC-1 protein 0.0095 0.0127 0.0143
Onchocerca volvulus Putative alcohol dehydrogenase 0.0216 0.0311 0.0326
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0013 0.0023
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0351 0.0517 0.0656
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0013 0.0002 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0095 0.0127 0.0127
Onchocerca volvulus 0.0049 0.0057 0.0059
Echinococcus granulosus glycine receptor subunit alpha 1 0.0095 0.0127 0.0236
Plasmodium vivax aspartyl proteinase, putative 0.0034 0.0034 0.0062
Echinococcus granulosus frizzled 0.0013 0.0002 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0049 0.0057 0.0064
Schistosoma mansoni tyrosine kinase 0.007 0.0089 0.0167
Mycobacterium tuberculosis Possible dehydrogenase 0.0216 0.0311 0.0394
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0013 0.0002 0.0008
Brugia malayi hypothetical protein 0.0169 0.024 0.024
Schistosoma mansoni lozenge 0.0021 0.0014 0.0027
Onchocerca volvulus 0.0044 0.0049 0.0051
Echinococcus granulosus Polycystic kidney disease protein 0.0029 0.0026 0.0048
Echinococcus multilocularis frizzled 5 0.0013 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0058 0.007 0.0079
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0216 0.0311 0.1297
Loa Loa (eye worm) disintegrin family protein 0.01 0.0135 0.0152
Echinococcus granulosus aldo keto reductase family 1 member B4 0.007 0.0088 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0391 0.0578 0.0578
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0081 0.0106 0.0106
Schistosoma mansoni hypothetical protein 0.0026 0.0021 0.004
Plasmodium vivax kinesin-5 0.0014 0.0003 0.0005
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0943 0.1419 0.5921
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0034 0.0063
Onchocerca volvulus 0.0015 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0062 0.0076 0.0096
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0028
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.3462 0.5258 0.6675
Schistosoma mansoni hypothetical protein 0.0118 0.0162 0.0302
Echinococcus multilocularis caspase 2 0.0118 0.0162 0.0302
Leishmania major quinone oxidoreductase, putative 0.0216 0.0311 0.1297
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0745 0.1118 0.1118
Echinococcus multilocularis rac serine:threonine kinase 0.0013 0.0001 0.0002
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0351 0.0517 0.0656
Mycobacterium ulcerans oxidoreductase 0.0216 0.0311 0.0394
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0049 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.5825 0.8859 1
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.3528 0.5359 1
Loa Loa (eye worm) hypothetical protein 0.023 0.0332 0.0375
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0032 0.003 0.0056
Brugia malayi nuclear receptor RXR 0.0035 0.0036 0.0036
Brugia malayi follicle stimulating hormone receptor 0.0049 0.0057 0.0057
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0038 0.004 0.0075
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0038 0.004 0.0167
Schistosoma mansoni retinoic acid receptor RXR 0.0067 0.0084 0.0157
Echinococcus granulosus serine/threonine protein kinase 0.0013 0.0001 0.0002
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0095 0.0127 0.0236
Giardia lamblia Aldose reductase 0.007 0.0088 0.0164
Onchocerca volvulus 0.0029 0.0026 0.0027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.007 0.0088 0.0165
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Schistosoma mansoni nuclear hormone receptor 0.0067 0.0084 0.0157
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0351 0.0517 0.0656
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.004
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0027 0.0023 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.0084 0.0084
Entamoeba histolytica kinesin, putative 0.0014 0.0003 0.0004
Plasmodium vivax multidomain scavenger receptor, putative 0.0029 0.0026 0.0047
Brugia malayi Receptor family ligand binding region containing protein 0.0016 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0074 0.0095 0.0176
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0013 0.0001 0.0002
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.1584 0.2397 0.4472
Echinococcus granulosus atrial natriuretic peptide receptor 0.0015 0.0005 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0068
Brugia malayi hypothetical protein 0.0034 0.0034 0.0034
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0062 0.0076 0.0096
Brugia malayi Zona pellucida-like domain containing protein 0.0044 0.0049 0.0049
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0036 0.0067
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0351 0.0517 0.3845
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0067 0.0084 0.0157
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0062 0.0076 0.0096
Schistosoma mansoni hypothetical protein 0.0013 0.0003 0.0005
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0057 0.0106
Echinococcus granulosus mitogen activated protein kinase 0.0044 0.0049 0.0091
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0351 0.0517 0.0656
Onchocerca volvulus 0.007 0.0088 0.0092
Loa Loa (eye worm) hypothetical protein 0.0029 0.0026 0.0029
Loa Loa (eye worm) hypothetical protein 0.0288 0.0421 0.0476
Mycobacterium leprae Possible oxidoreductase 0.002 0.0013 0.0016
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.023 0.0332 0.0375
Echinococcus granulosus cGMP dependent protein kinase 0.0013 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Loa Loa (eye worm) nuclear hormone receptor 0.0032 0.003 0.0034
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0095 0.0127 0.0236
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0062 0.0076 0.0096
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0068
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0022 0.0016 0.0018
Brugia malayi Steroid receptor seven-up type 2 0.0067 0.0084 0.0084
Onchocerca volvulus 0.0057 0.007 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0067 0.0084 0.0095
Toxoplasma gondii acyl carrier protein ACP 0.0351 0.0517 0.0925
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0051 0.0095
Leishmania major cathepsin L-like protease 0.0021 0.0013 0.0055
Schistosoma mansoni hypothetical protein 0.0046 0.0052 0.0097
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0023
Plasmodium vivax von Willebrand factor A domain-related protein, putative 0.0044 0.0049 0.0091
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0137 0.0191 0.0357
Schistosoma mansoni serine/threonine-protein kinase 0.0013 0.0001 0.0002
Mycobacterium leprae putative cytochrome p450 0.0062 0.0076 0.0096
Trichomonas vaginalis glucosylceramidase, putative 0.0049 0.0056 0.0104
Entamoeba histolytica acyl-CoA synthetase, putative 0.0351 0.0517 0.0964
Echinococcus granulosus NADH dehydrogenase 0.0351 0.0517 0.0964
Schistosoma mansoni tyrosine kinase 0.0016 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.3462 0.5258 0.6675
Loa Loa (eye worm) hypothetical protein 0.0033 0.0032 0.0036
Toxoplasma gondii aspartyl protease 0.0034 0.0034 0.006
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0216 0.0311 0.0394
Toxoplasma gondii type I fatty acid synthase 0.0533 0.0794 0.1421
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0018 0.001 0.004
Onchocerca volvulus 0.0018 0.001 0.001
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0033 0.0032 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Schistosoma mansoni nuclear receptor 0.0032 0.003 0.0056
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0014 0.0003 0.0005
Echinococcus granulosus serine threonine protein kinase nrc 0.0012 0 0.0001
Echinococcus multilocularis voltage gated potassium channel 0.003 0.0028 0.0053
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0057 0.0106
Schistosoma mansoni hypothetical protein 0.0468 0.0696 0.1299
Schistosoma mansoni lipoxygenase 0.0086 0.0113 0.021
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0013 0.0002 0.0004
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.004 0.0042 0.0176
Brugia malayi hypothetical protein 0.0127 0.0176 0.0176
Brugia malayi Matrixin family protein 0.0082 0.0107 0.0107
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0331 0.0487 0.0908
Onchocerca volvulus 0.0095 0.0127 0.0133
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0095 0.0127 0.0236
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0216 0.0311 0.0311
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.002 0.0012 0.0022
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0216 0.0311 0.1297
Brugia malayi Methyltransferase-like protein 4 0.1047 0.1577 0.1577
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0216 0.0311 0.0394
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0049 0.0057 0.0057
Echinococcus granulosus neuropeptide receptor 0.0049 0.0057 0.0106
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0038 0.004 0.0167
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0062 0.0116
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0872 0.1311 0.547
Loa Loa (eye worm) hypothetical protein 0.0169 0.024 0.0271
Entamoeba histolytica aldose reductase, putative 0.007 0.0088 0.0164
Loa Loa (eye worm) acetylcholinesterase 1 0.0031 0.0029 0.0032
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Echinococcus multilocularis cathepsin L cysteine protease 0.0021 0.0013 0.0025
Brugia malayi hypothetical protein 0.0044 0.0049 0.0049
Echinococcus multilocularis smoothened 0.0294 0.0431 0.0804
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.002 0.0012 0.0022
Onchocerca volvulus 0.0049 0.0057 0.0059
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.004
Loa Loa (eye worm) hypothetical protein 0.0081 0.0106 0.012
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0068 0.0085 0.0159
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.003 0.0056
Echinococcus multilocularis somatostatin receptor 0.0049 0.0057 0.0106
Onchocerca volvulus 0.0021 0.0013 0.0014
Loa Loa (eye worm) latrophilin receptor protein 2 0.0046 0.0052 0.0059
Leishmania major cytochrome p450-like protein 0.0114 0.0155 0.0647
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0062 0.0076 0.0096
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Leishmania major cysteine peptidase A (CPA) 0.0021 0.0013 0.0055
Schistosoma mansoni caspase-7 (C14 family) 0.0118 0.0162 0.0302
Plasmodium falciparum thrombospondin-related anonymous protein 0.0044 0.0049 0.0091
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0022
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0067 0.0084 0.0157
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.007 0.0088 0.0367
Schistosoma mansoni rab6-interacting 0.0029 0.0026 0.0048
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus granulosus adam 17 protease 0.0038 0.0039 0.0073
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0032 0.003 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Echinococcus granulosus chromobox protein 1 0.0029 0.0027 0.005
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0044 0.0049 0.0091
Trichomonas vaginalis glucosylceramidase, putative 0.0074 0.0095 0.0176
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Brugia malayi nuclear receptor NHR-88 0.0067 0.0084 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0057 0.0106
Brugia malayi Tachykinin-like peptides receptor 99D 0.0049 0.0057 0.0057
Echinococcus granulosus aldo keto reductase 0.007 0.0088 0.0165
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.3528 0.5359 1
Echinococcus granulosus frizzled 0.0013 0.0002 0.0004
Brugia malayi ADAMTS-like protease 0.0028 0.0025 0.0025
Plasmodium vivax circumsporozoite- and TRAP-related protein, putative 0.0044 0.0049 0.0091
Mycobacterium ulcerans Type I modular polyketide synthase 0.3462 0.5258 0.6675
Schistosoma mansoni biogenic amine receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Plasmodium falciparum von Willebrand factor A domain-related protein 0.0044 0.0049 0.0091
Mycobacterium ulcerans acyl carrier protein 0.0351 0.0517 0.0656
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0068
Loa Loa (eye worm) AGC/AKT protein kinase 0.0018 0.001 0.0011
Brugia malayi Cytochrome P450 family protein 0.0088 0.0117 0.0117
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.3528 0.5359 1
Echinococcus multilocularis GPCR, family 2 0.0046 0.0052 0.0097
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0246 0.0357 0.0357
Brugia malayi AKH receptor 0.0049 0.0057 0.0057
Echinococcus granulosus lactate dehydrogenase protein 0.0025 0.0021 0.0039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0014 0.0003 0.0005
Onchocerca volvulus 0.0044 0.0049 0.0051
Onchocerca volvulus 0.0021 0.0013 0.0014
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0026 0.0021 0.0039
Schistosoma mansoni amine GPCR 0.0049 0.0057 0.0106
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0038 0.004 0.0167
Echinococcus granulosus histone acetyltransferase KAT2B 0.0014 0.0003 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0049 0.0056 0.0104
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0057 0.0106
Loa Loa (eye worm) oxidoreductase 0.007 0.0088 0.01
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0057 0.0106
Mycobacterium ulcerans fatty acid synthase Fas 0.1091 0.1645 0.2088
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0051 0.006 0.006
Loa Loa (eye worm) cysteine protease 0.0021 0.0013 0.0015
Leishmania major cathepsin L-like protease 0.0078 0.0101 0.0422
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0709 0.1062 0.1981
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.001 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.0084 0.0157
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0067 0.0084 0.0095
Echinococcus granulosus neuropeptide receptor 0.0049 0.0057 0.0106
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Echinococcus granulosus tyrosine kinase 0.0016 0.0006 0.0011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0049 0.0057 0.0106
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0082 0.0107 0.02
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0219 0.0316 0.2291
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0013 0.0003 0.0005
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0345 0.0508 0.0508
Echinococcus granulosus neuropeptide FF receptor 2 0.0049 0.0057 0.0106
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0038 0.0039 0.0073
Loa Loa (eye worm) hypothetical protein 0.0081 0.0106 0.012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0021 0.0013 0.0025
Loa Loa (eye worm) glutamate receptor 2 0.0053 0.0063 0.0071
Echinococcus multilocularis hyperpolarization activated cyclic 0.0022 0.0016 0.0029
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0067 0.0084 0.0157
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0533 0.0794 0.1008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0039 0.0044
Brugia malayi Cathepsin L-like precursor 0.0021 0.0013 0.0013
Mycobacterium ulcerans Type I modular polyketide synthase 0.3462 0.5258 0.6675
Brugia malayi neuropeptide F receptor 0.0049 0.0057 0.0057
Onchocerca volvulus 0.0021 0.0013 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0018 0.001 0.0018
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.0032
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1732 0.2621 0.4891
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0018 0.0009 0.001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0331 0.0487 0.0908
Schistosoma mansoni nAChR subunit 0.0095 0.0127 0.0236
Echinococcus multilocularis p2X purinoceptor 4 0.0119 0.0164 0.0306
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0062 0.0076 0.0096
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0062 0.0076 0.0096
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0034 0.0063
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0034 0.0063
Loa Loa (eye worm) zinc metallopeptidase 4 0.0019 0.001 0.0012
Toxoplasma gondii cathepsin CPL 0.0021 0.0013 0.0024
Schistosoma mansoni dihydroceramide desaturase 0.0138 0.0192 0.0359
Schistosoma mansoni 60S ribosomal protein L21 0.0019 0.001 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0021 0.0013 0.0025
Trypanosoma cruzi acyl transferase-like protein, putative 0.0219 0.0316 0.1319
Echinococcus granulosus carbonic anhydrase 0.0081 0.0106 0.0198
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Loa Loa (eye worm) CYP4Cod1 0.0114 0.0155 0.0175
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0013 0.0002 0.0002
Onchocerca volvulus 0.0021 0.0013 0.0014
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0032 0.0059
Onchocerca volvulus 0.0095 0.0127 0.0133
Trypanosoma cruzi hypothetical protein, conserved 0.0943 0.1419 0.5921
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0021 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0062 0.0116
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0035 0.0035 0.0065
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0035 0.0035 0.0036
Toxoplasma gondii aldehyde dehydrogenase 0.0033 0.0032 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0062 0.0116
Mycobacterium tuberculosis Probable oxidoreductase 0.007 0.0088 0.0112
Loa Loa (eye worm) hypothetical protein 0.01 0.0134 0.0152
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0872 0.1311 0.2446
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.001 0.0042
Schistosoma mansoni hypothetical protein 0.0468 0.0696 0.1299
Plasmodium falciparum carbonic anhydrase 0.0081 0.0106 0.0198
Echinococcus multilocularis NADH dehydrogenase 0.0351 0.0517 0.0964
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Trypanosoma cruzi aminopeptidase, putative 0.0018 0.001 0.004
Plasmodium vivax vivapain-2 0.0021 0.0013 0.0025
Onchocerca volvulus 0.0082 0.0107 0.0112
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0049 0.0057 0.0106
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Schistosoma mansoni hypothetical protein 0.0212 0.0305 0.0569
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0034 0.0063
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0062 0.0076 0.0096
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0872 0.1311 0.547
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0057 0.0106
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0943 0.1419 0.2648
Echinococcus multilocularis potassium voltage gated channel protein 0.0046 0.0052 0.0097
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.3528 0.5359 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Loa Loa (eye worm) carboxylesterase 0.0031 0.0029 0.0032
Brugia malayi eukaryotic initiation factor 4A 0.0035 0.0035 0.0035
Mycobacterium tuberculosis Polyketide synthase Pks12 0.3678 0.5587 0.7093
Plasmodium vivax hypothetical protein, conserved 0.0331 0.0487 0.0908
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0066 0.0082 0.0104
Echinococcus multilocularis serotonin transporter 0.1808 0.2738 0.5109
Brugia malayi AMP-binding enzyme family protein 0.3246 0.4929 0.4929
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0216 0.0311 0.0394
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0013 0.0002 0.0004
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0051 0.006 0.006
Echinococcus granulosus collagen alpha 1VII chain 0.0044 0.0049 0.0091
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0709 0.1062 0.1982
Schistosoma mansoni thyroid hormone receptor 0.0067 0.0084 0.0157
Onchocerca volvulus 0.0014 0.0004 0.0004
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0036 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.0084 0.0157
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Schistosoma mansoni neurotransmitter gated ion channel 0.0044 0.0049 0.0091
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0095 0.0127 0.0236
Echinococcus multilocularis glutamate receptor 2 0.0137 0.0191 0.0357
Echinococcus multilocularis acetylcholinesterase 0.0031 0.0029 0.0053
Brugia malayi Cathepsin L-like cysteine proteinase 0.0014 0.0003 0.0003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0057 0.0106
Mycobacterium ulcerans aldehyde dehydrogenase 0.0033 0.0032 0.004
Loa Loa (eye worm) hypothetical protein 0.0046 0.0052 0.0058
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.1975 0.2992 0.3799
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0216 0.0311 0.0394
Onchocerca volvulus Cathepsin F homolog 0.0021 0.0013 0.0014
Trypanosoma cruzi Protein kinase B 0.0013 0.0001 0.0005
Loa Loa (eye worm) CUTiclin-Like family member 0.0044 0.0049 0.0055
Plasmodium vivax RNA helicase-1, putative 0.0035 0.0035 0.0065
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0062 0.0076 0.0096
Plasmodium falciparum acyl carrier protein 0.0351 0.0517 0.0964
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0062 0.0076 0.0096
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0022 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Leishmania major hypothetical protein, conserved 0.1047 0.1577 0.6581
Brugia malayi Kelch motif family protein 0.0192 0.0274 0.0274
Brugia malayi MH2 domain containing protein 0.012 0.0164 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.0084 0.0084
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.3246 0.4929 0.6258
Onchocerca volvulus 0.0029 0.0026 0.0027
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0015 0.0005 0.0009
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0072 0.0091 0.0379
Loa Loa (eye worm) hypothetical protein 0.0056 0.0068 0.0077
Echinococcus multilocularis frizzled 0.0013 0.0002 0.0004
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0033 0.0032 0.0131
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0094 0.0125 0.0158
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.005 0.0058 0.0065
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0046 0.0052 0.0097
Loa Loa (eye worm) hypothetical protein 0.0082 0.0107 0.0121
Echinococcus multilocularis microtubule associated protein 2 0.0256 0.0372 0.0694
Loa Loa (eye worm) hypothetical protein 0.0067 0.0084 0.0095
Echinococcus multilocularis aldo keto reductase 0.007 0.0088 0.0165
Brugia malayi angiogenesis inhibito 0.0028 0.0025 0.0025
Mycobacterium ulcerans polyketide synthase 0.3462 0.5258 0.6675
Mycobacterium ulcerans polyketide synthase Pks13 0.5181 0.7877 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Onchocerca volvulus 0.0044 0.0049 0.0051
Schistosoma mansoni nAChR subunit 0.0095 0.0127 0.0236
Echinococcus granulosus acetylcholinesterase 0.0031 0.0029 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0018 0.001 0.0018
Echinococcus multilocularis cysteine protease 0.0021 0.0013 0.0025
Echinococcus multilocularis serotonin receptor 0.0049 0.0057 0.0106
Schistosoma mansoni cathepsin D (A01 family) 0.009 0.012 0.0223
Schistosoma mansoni glutamate receptor NMDA 0.0053 0.0063 0.0117
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0074 0.0095 0.0178
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0062 0.0076 0.0096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Mycobacterium ulcerans short-chain dehydrogenase 0.0226 0.0326 0.0413
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0068
Trypanosoma brucei prostaglandin f synthase 0.007 0.0088 0.0367
Brugia malayi glutamate-cysteine ligase modifier subunit 0.002 0.0013 0.0013
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0038 0.0039 0.0073
Trichomonas vaginalis aldo/keto reductase, putative 0.007 0.0088 0.0164
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0872 0.1311 0.547
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0038
Trichomonas vaginalis AGC family protein kinase 0.0018 0.001 0.0018
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0062 0.0076 0.0316
Mycobacterium leprae PROBABLE HYDROLASE 0.01 0.0134 0.017
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0057 0.0106
Entamoeba histolytica cysteine protease, putative 0.0021 0.0013 0.0024
Schistosoma mansoni hypothetical protein 0.0091 0.012 0.0225
Brugia malayi Nuclear hormone receptor E75 0.0032 0.003 0.003
Brugia malayi Carboxylesterase family protein 0.0031 0.0029 0.0029
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0034 0.0063
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0095 0.0127 0.0127
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0216 0.0311 0.0394
Brugia malayi aspartic protease BmAsp-1, identical 0.0034 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Trypanosoma brucei aldo-keto reductase, putative 0.007 0.0088 0.0367
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0943 0.1419 0.2648
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0014 0.0003 0.0005
Echinococcus multilocularis L lactate dehydrogenase 0.0015 0.0006 0.0011
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0016 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Giardia lamblia Rab geranylgeranyltransferase 0.0943 0.1419 0.2648
Loa Loa (eye worm) hypothetical protein 0.0089 0.0118 0.0133
Trichomonas vaginalis CMGC family protein kinase 0.0044 0.0049 0.0091
Echinococcus multilocularis chromobox protein 1 0.0029 0.0027 0.005
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0095 0.0127 0.0236
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0013 0.0003 0.0005
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.007 0.0088 0.0164
Loa Loa (eye worm) TYRA-2 protein 0.0049 0.0057 0.0064
Echinococcus multilocularis L lactate dehydrogenase B chain 0.0025 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0111
Toxoplasma gondii hypothetical protein 0.0331 0.0487 0.0871
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0012 0 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0062 0.0076 0.0096
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0216 0.0311 0.0311
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0095 0.0126 0.0126
Trypanosoma cruzi aldo-keto reductase 0.007 0.0088 0.0367
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0062 0.0076 0.0096
Brugia malayi hypothetical protein 0.0029 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0067 0.0085 0.0095
Entamoeba histolytica hypothetical protein 0.0031 0.003 0.0055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0033 0.0032 0.004
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0068
Schistosoma mansoni adenoreceptor 0.0049 0.0057 0.0106
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0013 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Trypanosoma cruzi cytochrome P450, putative 0.0114 0.0155 0.0647
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0049 0.0049
Leishmania major eukaryotic initiation factor 4a, putative 0.0035 0.0035 0.0145
Loa Loa (eye worm) kinesin-like protein KLP2 0.0014 0.0003 0.0003
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0049 0.0057 0.0057
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0057 0.0106
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0035 0.0035 0.0065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0095 0.0127 0.0236
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0013 0.0002 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0044 0.0049 0.0087
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0351 0.0517 0.0656
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0216 0.0311 0.058
Brugia malayi MAP kinase sur-1 0.0044 0.0049 0.0049
Brugia malayi Matrixin family protein 0.0199 0.0285 0.0285
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0943 0.1419 0.2648
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0157 0.0221 0.0413
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0192 0.0274 0.031
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.004 0.0167
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0049 0.0057 0.0106
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.2845 0.4318 0.8057
Echinococcus granulosus sex peptide receptor 0.0049 0.0057 0.0106
Trypanosoma brucei carbonic anhydrase-like protein 0.0246 0.0357 0.1489
Entamoeba histolytica hypothetical protein, conserved 0.0044 0.0049 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Echinococcus granulosus thioredoxin glutathione reductase 0.0077 0.0099 0.0185
Trichomonas vaginalis conserved hypothetical protein 0.1047 0.1577 0.2943
Leishmania major geranylgeranyltransferase, putative 0.0709 0.1062 0.4431
Brugia malayi von Willebrand factor type A domain containing protein 0.0044 0.0049 0.0049
Onchocerca volvulus 0.0049 0.0057 0.0059
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0943 0.1419 0.5921
Giardia lamblia Kinase, CMGC MAPK 0.0044 0.0049 0.0091
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0038 0.004 0.0167
Brugia malayi Glutamate receptor 1 precursor 0.0142 0.0198 0.0198
Onchocerca volvulus 0.0034 0.0034 0.0035
Echinococcus granulosus glutamate receptor 4 0.0089 0.0118 0.022
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0014 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0446 0.0662 0.0747
Loa Loa (eye worm) reprolysin 0.0038 0.0039 0.0044
Trichomonas vaginalis alcohol dehydrogenase, putative 0.002 0.0013 0.0023
Toxoplasma gondii aspartyl protease ASP1 0.005 0.0058 0.0103
Toxoplasma gondii hypothetical protein 0.2585 0.3922 0.7019
Onchocerca volvulus 0.0116 0.0159 0.0167
Schistosoma mansoni biogenic amine receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) acetylcholine receptor protein 0.0044 0.0049 0.0055
Loa Loa (eye worm) GABA receptor subunit 0.0051 0.006 0.0068
Echinococcus granulosus voltage dependent calcium channel 0.0033 0.0032 0.0059
Toxoplasma gondii quinone oxidoreductase, putative 0.0216 0.0311 0.0556
Brugia malayi Dopamine receptor protein 2 0.0049 0.0057 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.0051 0.006 0.0111
Echinococcus granulosus cathepsin l1 0.0021 0.0013 0.0025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.003 0.0056
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0062 0.0076 0.0316
Schistosoma mansoni tyrosine kinase 0.0077 0.01 0.0186
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Schistosoma mansoni opsin-like receptor 0.0049 0.0057 0.0106
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0331 0.0487 0.0908
Echinococcus granulosus aldehyde reductase 0.005 0.0057 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0021 0.0013 0.0025
Trichomonas vaginalis aldo/keto reductase, putative 0.007 0.0088 0.0164
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0022 0.0016 0.0029
Brugia malayi Kinesin motor domain containing protein 0.0014 0.0003 0.0003
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0216 0.0311 0.0394
Schistosoma mansoni amine GPCR 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0038 0.004 0.0074
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0849 0.1276 0.1619
Schistosoma mansoni inhibitor of apoptosis protein 0.0391 0.0578 0.1079
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0014 0.0003 0.0005
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.002 0.0013 0.0014
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.002 0.0013 0.0052
Onchocerca volvulus 0.0331 0.0487 0.0511
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Loa Loa (eye worm) hypothetical protein 0.0089 0.0118 0.0133
Echinococcus granulosus endothelin converting enzyme 1 0.0076 0.0098 0.0184
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0351 0.0517 0.0656
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Echinococcus granulosus aldo keto reductase family 1, member B4 0.002 0.0013 0.0024
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0038 0.004 0.0074
Loa Loa (eye worm) nuclear receptor NHR-67 0.0032 0.003 0.0034
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0067 0.0084 0.0084
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0062 0.0076 0.0096
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0057 0.0106
Toxoplasma gondii acyl transferase domain-containing protein 0.0219 0.0316 0.0566
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.1405 0.2123 0.2695
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0057 0.0106
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0076 0.0098 0.0184
Toxoplasma gondii malate dehydrogenase MDH 0.0025 0.0021 0.0037
Schistosoma mansoni cathepsin F (C01 family) 0.0014 0.0003 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0067 0.0084 0.0095
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0246 0.0357 0.0666
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Entamoeba histolytica hypothetical protein 0.0015 0.0005 0.0008
Echinococcus multilocularis g-protein coupled receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Entamoeba histolytica PH domain containing protein kinase, putative 0.0013 0.0001 0.0002
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0018 0.001 0.0018
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0032 0.0059
Onchocerca volvulus 0.0049 0.0057 0.0059
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.1091 0.1645 0.2088
Toxoplasma gondii type I fatty acid synthase, putative 0.2473 0.3751 0.6714
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0872 0.1311 0.2447
Onchocerca volvulus 0.0044 0.0049 0.0051
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0299 0.0437 0.0816
Echinococcus granulosus voltage gated potassium channel subunit 0.002 0.0013 0.0024
Plasmodium falciparum plasmepsin VII 0.0034 0.0034 0.0062
Echinococcus multilocularis voltage gated potassium channel subunit 0.002 0.0013 0.0024
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.1584 0.2397 0.4472
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0062 0.0076 0.0096
Echinococcus multilocularis aldo keto reductase 0.007 0.0088 0.0165
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0022 0.0016 0.0029
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0216 0.0311 0.2249
Toxoplasma gondii lactate dehydrogenase LDH2 0.0025 0.0021 0.0037
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0062 0.0076 0.0096
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0023 0.0017 0.002
Echinococcus granulosus nAChR subunit 0.0095 0.0127 0.0236
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0049 0.0057 0.0106
Echinococcus multilocularis lipoxygenase domain containing protein 0.0029 0.0026 0.0048
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0331 0.0487 0.0908
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0038 0.004 0.0051
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.023 0.0332 0.0619
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0057 0.0106
Mycobacterium ulcerans zinc metalloprotease 0.0076 0.0098 0.0125
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0015 0.0005 0.0005
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0068 0.0085 0.0159
Echinococcus multilocularis nmda type glutamate receptor 0.002 0.0012 0.0022
Schistosoma mansoni cathepsin D (A01 family) 0.009 0.012 0.0223
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0076 0.0098 0.0125
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0013 0.0001 0.0005
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0049 0.0057 0.0064
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0033 0.0032 0.004
Entamoeba histolytica aldose reductase, putative 0.007 0.0088 0.0164
Onchocerca volvulus 0.0021 0.0013 0.0014
Echinococcus granulosus aldo keto reductase 0.007 0.0088 0.0165
Echinococcus multilocularis carbonic anhydrase 0.0081 0.0106 0.0198
Loa Loa (eye worm) oxidoreductase 0.007 0.0088 0.01
Echinococcus granulosus glutamate receptor 2 0.0157 0.0221 0.0413
Brugia malayi hypothetical protein 0.0035 0.0036 0.0036
Loa Loa (eye worm) acyl carrier protein 0.0351 0.0517 0.0583
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0062 0.0076 0.0096
Loa Loa (eye worm) DR-78 0.0032 0.003 0.0034
Echinococcus multilocularis Protein lozenge 0.0021 0.0014 0.0027
Echinococcus granulosus dna polymerase kappa 0.0022 0.0016 0.0029
Echinococcus multilocularis serotonin receptor 0.0049 0.0057 0.0106
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0331 0.0487 0.0871
Leishmania major eukaryotic initiation factor 4a, putative 0.0035 0.0035 0.0145
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0067 0.0084 0.0095
Onchocerca volvulus 0.0049 0.0057 0.0059
Loa Loa (eye worm) aminopeptidase N 0.0018 0.001 0.0011
Leishmania major extracellular receptor, putative 0.0015 0.0005 0.0019
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0533 0.0794 0.1008
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0331 0.0487 0.0908
Schistosoma mansoni sodium-dependent amino acid transporter 0.0331 0.0487 0.0908
Trypanosoma cruzi aldo/keto reductase, putative 0.007 0.0088 0.0367
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0046 0.0052 0.0052
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0095 0.0127 0.0127
Brugia malayi conserved hypotetical protein 0.0032 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0021 0.0024
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0095 0.0127 0.0127
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.007 0.0088 0.0088
Trichomonas vaginalis CMGC family protein kinase 0.0044 0.0049 0.0091
Echinococcus multilocularis integrin alpha ps 0.0212 0.0305 0.0569
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0049 0.0057 0.0106
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0016 0.0029
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0345 0.0508 0.2117
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0216 0.0311 0.0394
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0062 0.0116
Plasmodium falciparum protein farnesyltransferase subunit beta 0.1584 0.2397 0.4472
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0036 0.0036
Toxoplasma gondii cytochrome p450 superfamily protein 0.1767 0.2675 0.4788
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Echinococcus multilocularis orexin receptor type 2 0.0049 0.0057 0.0106
Echinococcus multilocularis chromobox protein 1 0.0029 0.0027 0.005
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0943 0.1419 0.2648
Mycobacterium ulcerans hydrolase 0.01 0.0134 0.017
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0033 0.0032 0.0059
Brugia malayi Cathepsin L-like precursor 0.0021 0.0013 0.0013
Echinococcus multilocularis glutamate receptor 2 0.0157 0.0221 0.0413
Echinococcus multilocularis nuclear receptor nhr 48 0.0032 0.003 0.0056
Loa Loa (eye worm) hypothetical protein 0.0331 0.0487 0.0549
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0021 0.0013 0.0025
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0709 0.1062 0.1062
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0074 0.0095 0.0178
Schistosoma mansoni frizzled 0.0013 0.0002 0.0004
Echinococcus granulosus acyl carrier protein mitochondrial 0.0351 0.0517 0.0964
Schistosoma mansoni aldo-keto reductase 0.007 0.0088 0.0165
Plasmodium falciparum plasmepsin V 0.0034 0.0034 0.0062
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0067 0.0084 0.0095
Brugia malayi von Willebrand factor type A domain containing protein 0.0044 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.0049 0.0057 0.0106
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.5181 0.7877 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.004
Schistosoma mansoni frizzled-like receptor 0.0013 0.0002 0.0004
Loa Loa (eye worm) matrixin family protein 0.0182 0.026 0.0293
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0033 0.0032 0.0059
Echinococcus multilocularis Polycystic kidney disease protein 0.0029 0.0026 0.0048
Echinococcus multilocularis lipoxygenase domain containing protein 0.0029 0.0026 0.0048
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0046 0.0052 0.0097
Onchocerca volvulus Deterin homolog 0.0391 0.0578 0.0607
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0709 0.1062 0.1981
Plasmodium falciparum L-lactate dehydrogenase 0.0025 0.0021 0.0038
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0018 0.001 0.0018
Schistosoma mansoni chromobox protein 0.0029 0.0027 0.005
Brugia malayi Eukaryotic aspartyl protease family protein 0.0034 0.0034 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0709 0.1062 0.4431
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0709 0.1062 0.1981
Toxoplasma gondii kinesin motor domain-containing protein 0.0014 0.0003 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.0067 0.0084 0.0157
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0032 0.0059
Echinococcus granulosus metabotropic glutamate receptor 5 0.0035 0.0036 0.0066
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0028 0.0025 0.0025
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0331 0.0487 0.0871
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0028 0.0053
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0022 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0068
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0219 0.0316 0.0401
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0062 0.0076 0.0096
Onchocerca volvulus 0.007 0.0088 0.0092
Brugia malayi NADH-dependent xylose reductase 0.002 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0067 0.0084 0.0157
Brugia malayi Disintegrin family protein 0.0138 0.0192 0.0192
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0052 0.0097
Mycobacterium tuberculosis Possible dehydrogenase 0.0216 0.0311 0.0394
Entamoeba histolytica protein kinase, putative 0.0018 0.0009 0.0016
Brugia malayi hypothetical protein 0.0066 0.0082 0.0082
Schistosoma mansoni P2X receptor subunit 0.0119 0.0164 0.0306
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0038 0.004 0.0071
Echinococcus granulosus glutamate receptor subunit protein glur 0.0109 0.0148 0.0276
Plasmodium falciparum thioredoxin reductase 0.0077 0.0099 0.0185
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.01 0.0134 0.0134
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0019 0.001 0.0019
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.3462 0.5258 0.5258
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0085 0.0111 0.0206
Loa Loa (eye worm) fatty acid synthase 0.3428 0.5207 0.5878
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0047 0.0054 0.01
Loa Loa (eye worm) hypothetical protein 0.0383 0.0566 0.0639
Echinococcus multilocularis disintegrin and metalloproteinase 0.0138 0.0192 0.0359
Echinococcus granulosus nuclear receptor nhr 48 0.0032 0.003 0.0056
Leishmania major cytochrome p450-like protein 0.0062 0.0076 0.0316
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0331 0.0487 0.0908
Mycobacterium tuberculosis Conserved protein 0.002 0.0013 0.0016
Onchocerca volvulus 0.0038 0.004 0.0041
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0216 0.0311 0.0351
Brugia malayi RE15519p 0.0049 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0018
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0081 0.0106 0.0106
Brugia malayi Cytochrome P450 family protein 0.0062 0.0076 0.0076
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.004 0.0042 0.0079
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0331 0.0487 0.3711
Echinococcus granulosus aldo keto reductase family 1 member B4 0.007 0.0088 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0067 0.0084 0.0084
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.003 0.0028 0.0053
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0157 0.0221 0.0413
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Echinococcus multilocularis sodium and chloride dependent glycine 0.0383 0.0566 0.1056
Mycobacterium ulcerans thioesterase 0.2895 0.4395 0.5579
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0018 0.001 0.0018
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0066 0.0082 0.0104
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0044 0.0049 0.0049
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0709 0.1062 0.1981
Echinococcus granulosus voltage dependent calcium channel subunit 0.0044 0.0049 0.0091
Loa Loa (eye worm) hypothetical protein 0.007 0.0088 0.01
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.004
Loa Loa (eye worm) hypothetical protein 0.0099 0.0133 0.015
Schistosoma mansoni chromobox protein 0.0029 0.0027 0.005
Schistosoma mansoni biogenic amine receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0051 0.006 0.0112
Brugia malayi Dopamine receptor protein 1 0.0049 0.0057 0.0057
Mycobacterium ulcerans quinone oxidoreductase 0.0216 0.0311 0.0394
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0145 0.0203 0.0203
Schistosoma mansoni voltage-gated potassium channel 0.0046 0.0052 0.0097
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0057 0.0106
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Onchocerca volvulus 0.0049 0.0057 0.0059
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.005 0.0058 0.0108
Plasmodium vivax aspartyl protease, putative 0.0034 0.0034 0.0062
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0095 0.0127 0.0236
Toxoplasma gondii hypothetical protein 0.0943 0.1419 0.254
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0872 0.1311 0.2447
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0216 0.0311 0.058
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0062 0.0076 0.0096
Trypanosoma cruzi protein farnesyltransferase, putative 0.1584 0.2397 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0066 0.0082 0.0104
Plasmodium falciparum transporter, putative 0.0331 0.0487 0.0908
Brugia malayi Carboxylesterase family protein 0.0031 0.0029 0.0029
Schistosoma mansoni coup transcription factor 0.0067 0.0084 0.0157
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Entamoeba histolytica cysteine proteinase, putative 0.0021 0.0013 0.0024
Onchocerca volvulus 0.0044 0.0049 0.0051
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.004 0.0042 0.0176
Leishmania major prostaglandin f synthase, putative 0.007 0.0088 0.0367
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0095 0.0127 0.0236
Entamoeba histolytica cysteine proteinase, putative 0.0021 0.0013 0.0024
Schistosoma mansoni hypothetical protein 0.0046 0.0052 0.0097
Toxoplasma gondii microneme protein MIC2 0.0044 0.0049 0.0087
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0034 0.0034 0.0038
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0351 0.0517 0.0656
Onchocerca volvulus 0.0049 0.0057 0.0059
Plasmodium falciparum plasmepsin II 0.005 0.0058 0.0108
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.004 0.0167
Chlamydia trachomatis acyl carrier protein 0.0351 0.0517 0.3941
Loa Loa (eye worm) fibroinase 0.0021 0.0013 0.0015
Schistosoma mansoni nuclear receptor 0.0032 0.003 0.0056
Schistosoma mansoni integrin alpha-ps 0.023 0.0333 0.0621
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.003 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0023
Brugia malayi Alcohol dehydrogenase class III 0.0216 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0111
Echinococcus multilocularis lactate dehydrogenase protein 0.0025 0.0021 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0018 0.001 0.0018
Echinococcus multilocularis sodium and chloride dependent glycine 0.0383 0.0566 0.1056
Schistosoma mansoni methyltransferase-related 0.1047 0.1577 0.2943
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.2783 0.4224 0.5362
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0035 0.0035 0.0065
Mycobacterium leprae Probable oxidireductase 0.0216 0.0311 0.0394
Schistosoma mansoni survival motor neuron protein 0.0026 0.0021 0.004
Schistosoma mansoni glutamate receptor AMPA 0.0053 0.0063 0.0117
Echinococcus multilocularis thioredoxin glutathione reductase 0.0077 0.0099 0.0185
Plasmodium falciparum histone acetyltransferase GCN5 0.0013 0.0001 0.0002
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0022 0.0016 0.0029
Onchocerca volvulus 0.0049 0.0057 0.0059
Trypanosoma cruzi oxidoreductase, putative 0.0216 0.0311 0.1297
Brugia malayi hypothetical protein 0.0029 0.0026 0.0026
Plasmodium falciparum plasmepsin I 0.005 0.0058 0.0108
Echinococcus granulosus serotonin receptor 0.0049 0.0057 0.0106
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.003 0.0056
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0367 0.0541 0.0611
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0034 0.0063
Brugia malayi Nuclear hormone receptor E75 0.0032 0.003 0.003
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Brugia malayi von Willebrand Factor 0.0044 0.0049 0.0049
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Echinococcus granulosus g protein coupled receptor 0.0049 0.0057 0.0106
Onchocerca volvulus 0.0044 0.0049 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0067 0.0084 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Echinococcus granulosus cathepsin l1 0.0014 0.0003 0.0006
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.1584 0.2397 0.4289
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Onchocerca volvulus 0.0216 0.0311 0.0326
Entamoeba histolytica elongation factor-2 kinase, putative 0.0044 0.0049 0.0091
Echinococcus granulosus aldo keto reductase family 1 member B4 0.007 0.0088 0.0165
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0038 0.004 0.0167
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0351 0.0517 0.0656
Brugia malayi von Willebrand factor type A domain containing protein 0.0044 0.0049 0.0049
Schistosoma mansoni nAChR subunit 0.0095 0.0127 0.0236
Schistosoma mansoni acetylcholine receptor-related 0.0044 0.0049 0.0091
Echinococcus multilocularis nAChR subunit 0.0051 0.006 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0001 0.0002
Brugia malayi Serotonin receptor 0.0049 0.0057 0.0057
Echinococcus granulosus nmda type glutamate receptor 0.002 0.0012 0.0022
Brugia malayi hypothetical protein 0.0018 0.001 0.001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Brugia malayi Peptidase family M1 containing protein 0.0018 0.001 0.001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.0084 0.0157
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0062 0.0076 0.0316
Echinococcus multilocularis carbonic anhydrase II 0.0246 0.0357 0.0666
Schistosoma mansoni hypothetical protein 0.0046 0.0052 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0176 0.0251 0.0283
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0051 0.006 0.006
Echinococcus granulosus carbonic anhydrase 0.0081 0.0106 0.0198
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0062 0.0076 0.0096
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0067 0.0084 0.0157
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0044 0.0049 0.0091
Entamoeba histolytica alcohol dehydrogenase, putative 0.002 0.0013 0.0023
Echinococcus multilocularis collagen alpha 1(VII) chain 0.0044 0.0049 0.0091
Echinococcus granulosus apoptotic protease activating factor 1 0.0118 0.0162 0.0302
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.004
Schistosoma mansoni hypothetical protein 0.0029 0.0026 0.0048
Echinococcus multilocularis tumor protein p63 0.0097 0.013 0.0242
Echinococcus granulosus glutamate receptor 1 0.0089 0.0118 0.022
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0034 0.0034 0.006
Schistosoma mansoni hypothetical protein 0.0099 0.0133 0.0248
Mycobacterium ulcerans aminopeptidase N PepN 0.0018 0.001 0.0012
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0022 0.0016 0.0029
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0028 0.0053
Mycobacterium ulcerans hypothetical protein 0.002 0.0013 0.0016
Mycobacterium ulcerans quinone oxidoreductase 0.0216 0.0311 0.0394
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0028
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0072 0.0091 0.017
Plasmodium vivax plasmepsin IV, putative 0.005 0.0058 0.0108
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0029 0.0027 0.005
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.005 0.0058 0.0108
Echinococcus multilocularis aldo keto reductase 0.007 0.0088 0.0165
Schistosoma mansoni cathepsin F (C01 family) 0.0021 0.0013 0.0025
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0943 0.1419 0.5921
Trichomonas vaginalis glucosylceramidase, putative 0.0074 0.0095 0.0176
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0068 0.0085 0.0159
Mycobacterium ulcerans polyketide synthase MbtD 0.1068 0.161 0.2044
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0081 0.0106 0.0106
Schistosoma mansoni integrin beta subunit 0.0703 0.1053 0.1964
Loa Loa (eye worm) ACC-1 protein 0.0095 0.0127 0.0143
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Schistosoma mansoni [ACP] S-malonyltransferase 0.0219 0.0316 0.059
Trichomonas vaginalis AGC family protein kinase 0.0018 0.001 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Echinococcus granulosus frizzled 4 0.0013 0.0002 0.0004
Echinococcus multilocularis lactate dehydrogenase a 0.0025 0.0021 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0005
Brugia malayi Melatonin receptor type 1A 0.0049 0.0057 0.0057
Mycobacterium ulcerans quinone reductase Qor 0.0216 0.0311 0.0394
Loa Loa (eye worm) hypothetical protein 0.0058 0.007 0.0079
Schistosoma mansoni hypothetical protein 0.0049 0.0057 0.0106
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0016 0.0064
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.0219 0.0316 0.2411
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0049 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.1808 0.2738 0.3091
Brugia malayi peptidase family M13 containing protein 0.0019 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.023 0.0333 0.0375
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0062 0.0076 0.0096
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0216 0.0311 0.0394
Loa Loa (eye worm) hypothetical protein 0.0058 0.007 0.0079
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0022 0.0016 0.0029
Leishmania major cytochrome p450-like protein 0.0062 0.0076 0.0316
Brugia malayi Matrixin family protein 0.0082 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Echinococcus multilocularis geminin 0.0468 0.0696 0.1299
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0331 0.0487 0.0908
Loa Loa (eye worm) hypothetical protein 0.0118 0.0162 0.0183
Loa Loa (eye worm) melatonin receptor type 1A 0.0049 0.0057 0.0064
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0038 0.004 0.004
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0095 0.0127 0.0127
Schistosoma mansoni histamine h1 receptor 0.0049 0.0057 0.0106
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.3678 0.5587 0.7093
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0095 0.0127 0.0127
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0022 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0872 0.1311 0.1664
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0013 0.0002 0.0008
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0044 0.0049 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0049 0.0056 0.0104
Brugia malayi chromobox protein homolog 3 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0331 0.0487 0.0549
Schistosoma mansoni hypothetical protein 0.0391 0.0578 0.1079
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0067 0.0084 0.0095
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0049 0.0057 0.0059
Brugia malayi Papain family cysteine protease containing protein 0.0021 0.0013 0.0013
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0709 0.1062 0.4431
Mycobacterium tuberculosis Probable oxidoreductase 0.0216 0.0311 0.0394
Brugia malayi nuclear hormone receptor 0.0032 0.003 0.003
Treponema pallidum sodium- and chloride- dependent transporter 0.1808 0.2738 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0067 0.0084 0.0157
Echinococcus multilocularis neuropeptide s receptor 0.1159 0.1749 0.3263
Onchocerca volvulus Bile acid receptor homolog 0.0067 0.0084 0.0088
Trypanosoma cruzi lanosterol synthase, putative 0.0793 0.1191 0.497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0057 0.0106
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.3678 0.5587 0.7093
Echinococcus granulosus eukaryotic initiation factor 4A 0.0035 0.0035 0.0065
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Loa Loa (eye worm) serotonin transporter b 0.1808 0.2738 0.3091
Echinococcus granulosus cGMP dependent protein kinase 1 0.0013 0.0001 0.0002
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.005 0.0058 0.0108
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0145 0.0203 0.038
Onchocerca volvulus 0.0018 0.001 0.001
Schistosoma mansoni glutamate receptor NMDA 0.0068 0.0085 0.0159
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0044 0.0049 0.0091
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0095 0.0126 0.0236
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.007 0.0088 0.0088
Echinococcus multilocularis FTZ F1 alpha 0.0067 0.0084 0.0157
Trypanosoma cruzi cysteine peptidase, putative 0.0078 0.0101 0.0422
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0095 0.0127 0.0127
Echinococcus granulosus g protein coupled receptor 0.0049 0.0057 0.0106
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0035 0.0035 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0035 0.0035 0.0065
Brugia malayi glutathione reductase 0.0077 0.0099 0.0099
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0049 0.0057 0.0106
Schistosoma mansoni sodium/chloride dependent transporter 0.0384 0.0567 0.1058
Loa Loa (eye worm) hypothetical protein 0.0058 0.007 0.0079
Loa Loa (eye worm) hypothetical protein 0.0095 0.0127 0.0143
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.007 0.0088 0.0088
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0044 0.0049 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0007 0.0013
Onchocerca volvulus Huntingtin homolog 0.0087 0.0115 0.012
Plasmodium falciparum cGMP-dependent protein kinase 0.0013 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Trypanosoma brucei lanosterol synthase 0.0793 0.1191 0.497
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0038 0.0039 0.0073
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0943 0.1419 0.5921
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0216 0.0311 0.058
Brugia malayi nuclear receptor NHR-67 0.0032 0.003 0.003
Echinococcus multilocularis nAChR subunit 0.0095 0.0127 0.0236
Echinococcus multilocularis nuclear factor of activated T cells 5 0.004 0.0042 0.0079
Loa Loa (eye worm) hypothetical protein 0.0145 0.0203 0.0229
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.0084 0.0084
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0051 0.0095
Leishmania major protein kinase, putative 0.0013 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0052 0.0061 0.0069
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0046 0.0052 0.0097
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0062 0.0076 0.0316
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0057 0.0106
Plasmodium vivax amine transporter, putative 0.0331 0.0487 0.0908
Schistosoma mansoni glutamate receptor AMPA 0.0053 0.0063 0.0117
Loa Loa (eye worm) CUTiclin family member 0.0044 0.0049 0.0055
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.3528 0.5359 1
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0216 0.0311 0.0556
Plasmodium falciparum plasmepsin IV 0.005 0.0058 0.0108
Plasmodium vivax prenyltransferase alpha subunit, putative 0.3528 0.5359 1
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.2845 0.4318 0.8057
Entamoeba histolytica hypothetical protein 0.0013 0.0003 0.0004
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0035 0.0035 0.0145
Loa Loa (eye worm) hypothetical protein 0.0046 0.0052 0.0059
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0018 0.001 0.0018
Brugia malayi von Willebrand factor type A domain containing protein 0.0044 0.0049 0.0049
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0046 0.0052 0.0097
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0216 0.0311 0.0394
Echinococcus granulosus somatostatin receptor 0.0049 0.0057 0.0106
Echinococcus multilocularis frizzled 0.0013 0.0002 0.0004
Echinococcus multilocularis carbonic anhydrase 0.0081 0.0106 0.0198
Brugia malayi Protein kinase domain containing protein 0.0018 0.001 0.001
Brugia malayi Cation transporter family protein 0.0095 0.0127 0.0127
Entamoeba histolytica aminopeptidase, putative 0.0018 0.001 0.0018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0051 0.0095
Brugia malayi von Willebrand factor type A domain containing protein 0.0044 0.0049 0.0049
Loa Loa (eye worm) oxidoreductase 0.007 0.0088 0.01
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.004 0.0042 0.0079
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.2285 0.3465 0.4398
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0034 0.0063
Echinococcus granulosus L lactate dehydrogenase B chain 0.0025 0.0021 0.0039
Treponema pallidum NADH oxidase 0.0038 0.004 0.0146
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0032 0.003 0.0056
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0383 0.0566 0.0566
Schistosoma mansoni memapsin-2 (A01 family) 0.0549 0.0819 0.1527
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0032
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0017 0.0017
Loa Loa (eye worm) von Willebrand factor type A domain-containing protein 0.0044 0.0049 0.0055
Echinococcus granulosus G protein coupled receptor 139 0.0049 0.0057 0.0106
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0072 0.0091 0.017
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0216 0.0311 0.0394
Loa Loa (eye worm) hypothetical protein 0.0391 0.0578 0.0653
Loa Loa (eye worm) hypothetical protein 0.0051 0.006 0.0068
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.023 0.0332 0.0332
Leishmania major malate dehydrogenase, putative 0.0025 0.0021 0.0085
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0016 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0062 0.0116
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.004 0.0042 0.0079
Echinococcus granulosus hyperpolarization activated cyclic 0.0022 0.0016 0.0029
Brugia malayi hypothetical protein 0.0032 0.003 0.003
Echinococcus multilocularis mitogen activated protein kinase 0.0044 0.0049 0.0091
Onchocerca volvulus 0.0361 0.0532 0.0558
Loa Loa (eye worm) cytochrome P450 0.0062 0.0076 0.0086
Brugia malayi steroid hormone receptor 0.0067 0.0084 0.0084
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.1584 0.2397 0.4472
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Schistosoma mansoni nAChR subunit 0.0044 0.0049 0.0091
Brugia malayi G protein-coupled receptor F59B2.13 0.0049 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0067 0.0084 0.0095
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.007 0.0088 0.0165
Brugia malayi hypothetical protein 0.0035 0.0036 0.0036
Plasmodium falciparum LCCL domain-containing protein 0.0029 0.0026 0.0047
Brugia malayi hypothetical protein 0.0192 0.0274 0.0274
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0077 0.0099 0.0126
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0391 0.0578 0.0578
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0018 0.001 0.0018
Loa Loa (eye worm) integrin alpha pat-2 0.0975 0.1469 0.1658
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Echinococcus granulosus metabotropic glutamate receptor 2 0.0015 0.0005 0.0009
Plasmodium vivax SET domain protein, putative 0.0053 0.0062 0.0116
Schistosoma mansoni acetylcholine receptor subunit beta 0.0044 0.0049 0.0091
Leishmania major lanosterol synthase, putative 0.0085 0.0111 0.0463
Giardia lamblia Rab geranylgeranyltransferase 0.3528 0.5359 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0057 0.0106
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0062 0.0076 0.0096
Brugia malayi cytochrome P450 0.0062 0.0076 0.0076
Trichomonas vaginalis aldo-keto reductase, putative 0.007 0.0088 0.0164
Leishmania major cathepsin L-like protease 0.0021 0.0013 0.0055
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0067 0.0085 0.0095
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0246 0.0357 0.0666
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0067 0.0084 0.0157
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0018 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.0219 0.0316 0.1319
Brugia malayi Peptidase family M1 containing protein 0.0018 0.001 0.001
Brugia malayi Cathepsin L-like precursor 0.0014 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0943 0.1419 0.5921
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0067 0.0084 0.0157
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0022 0.0016 0.0029
Trichomonas vaginalis aldo-keto reductase, putative 0.002 0.0013 0.0023
Trichomonas vaginalis set domain proteins, putative 0.0418 0.0618 0.1153
Loa Loa (eye worm) hypothetical protein 0.0067 0.0084 0.0095
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0216 0.0311 0.1297
Schistosoma mansoni neurotransmitter gated ion channel 0.0051 0.006 0.0112
Echinococcus granulosus aldo keto reductase 0.007 0.0088 0.0165
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0038 0.004 0.0167
Plasmodium vivax aldehyde reductase, putative 0.002 0.0013 0.0023
Echinococcus granulosus voltage gated potassium channel 0.003 0.0028 0.0053
Leishmania major protein kinase, putative 0.0013 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0345 0.0508 0.0573
Echinococcus granulosus inhibitor of apoptosis protein 0.0391 0.0578 0.1079
Loa Loa (eye worm) hypothetical protein 0.0083 0.0108 0.0122
Schistosoma mansoni hypothetical protein 0.0081 0.0106 0.0198
Echinococcus granulosus hypothetical protein 0.042 0.0622 0.116
Plasmodium vivax hypothetical protein, conserved 0.0508 0.0756 0.141
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0038 0.004 0.0305
Schistosoma mansoni serine/threonine-protein kinase 0.0013 0.0001 0.0002
Entamoeba histolytica PH domain containing protein kinase, putative 0.0013 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0038 0.004 0.0167
Giardia lamblia Aldose reductase 0.007 0.0088 0.0164
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0095 0.0127 0.0143
Schistosoma mansoni integrin alpha 0.0442 0.0655 0.1223
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.2895 0.4395 0.5579
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0049 0.0057 0.0106
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0085 0.0111 0.0206
Entamoeba histolytica hypothetical protein 0.0051 0.006 0.0111
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0246 0.0357 0.0403
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0095 0.0127 0.0236
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.002 0.0012 0.0022
Brugia malayi nuclear receptor RXR 0.0032 0.003 0.003
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0034 0.0063
Echinococcus granulosus cytochrome P450 2K1 0.0062 0.0076 0.0142
Giardia lamblia Methyltransferase like 2 0.1047 0.1577 0.2943
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0067 0.0084 0.0157
Plasmodium falciparum glutathione reductase 0.0077 0.0099 0.0185
Onchocerca volvulus 0.0021 0.0013 0.0014
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.007 0.0088 0.0367
Onchocerca volvulus 0.1808 0.2738 0.2874
Loa Loa (eye worm) hypothetical protein 0.0118 0.0162 0.0183
Brugia malayi nuclear receptor NHR-88 0.0032 0.003 0.003
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0033 0.0032 0.0059
Echinococcus granulosus p2X purinoceptor 4 0.0119 0.0164 0.0306
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0032 0.003 0.0056
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0391 0.0578 0.1079
Onchocerca volvulus Glucosylceramidase homolog 0.0049 0.0056 0.0059
Echinococcus granulosus tumor protein p63 0.0097 0.013 0.0242
Loa Loa (eye worm) solute carrier family 6 member 4 0.1808 0.2738 0.3091
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.003 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0021 0.0013 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0016 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Treponema pallidum acyl carrier protein 0.0351 0.0517 0.1887
Echinococcus multilocularis survival motor neuron protein 1 0.0127 0.0176 0.0328
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.0084 0.0084
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0246 0.0357 0.1489
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0067 0.0084 0.0157
Onchocerca volvulus Putative nachr subunit 0.023 0.0332 0.0348
Toxoplasma gondii von Willebrand factor type A domain-containing protein 0.0044 0.0049 0.0087
Onchocerca volvulus 0.007 0.0088 0.0092
Echinococcus multilocularis cysteine protease 0.0021 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Brugia malayi Integrin beta pat-3 precursor 0.1221 0.1844 0.1844
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0216 0.0311 0.0394
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0049 0.0057 0.0106
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.2285 0.3465 0.4398
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0943 0.1419 0.2648
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.023 0.0332 0.0619
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0069 0.0087 0.0098
Toxoplasma gondii thioredoxin reductase 0.0077 0.0099 0.0177
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.3462 0.5258 0.6675
Loa Loa (eye worm) RGC/RGC protein kinase 0.0016 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Onchocerca volvulus Neuropeptide F receptor homolog 0.0049 0.0057 0.0059
Echinococcus multilocularis acetylcholinesterase 0.0031 0.0029 0.0053
Plasmodium vivax plasmepsin V, putative 0.0034 0.0034 0.0062
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0057 0.0106
Brugia malayi von Willebrand factor type A domain containing protein 0.0044 0.0049 0.0049
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0067 0.0084 0.0157
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0021 0.0013 0.0025
Giardia lamblia Kinesin-5 0.0014 0.0003 0.0005
Onchocerca volvulus 0.0331 0.0487 0.0511
Schistosoma mansoni myosin xvIII 0.0049 0.0057 0.0106
Onchocerca volvulus 0.0032 0.003 0.0031
Echinococcus granulosus potassium voltage gated channel subfamily H 0.003 0.0028 0.0053
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0219 0.0316 0.059
Echinococcus granulosus carboxylesterase 5A 0.0031 0.0029 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0007 0.0013
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0023
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0095 0.0127 0.0143
Brugia malayi Hemopexin family protein 0.0116 0.0159 0.0159
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0216 0.0311 0.0394
Echinococcus granulosus integrin alpha 3 0.0212 0.0305 0.0569
Mycobacterium tuberculosis Polyketide synthase Pks13 0.5181 0.7877 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0038
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0216 0.0311 0.1297
Loa Loa (eye worm) aspartic protease BmAsp-2 0.005 0.0058 0.0065
Echinococcus multilocularis cathepsin L cysteine protease 0.0021 0.0013 0.0025
Schistosoma mansoni neuropeptide receptor 0.0049 0.0057 0.0106
Schistosoma mansoni nAChR subunit 0.0044 0.0049 0.0091
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0038 0.0039 0.0073
Loa Loa (eye worm) hypothetical protein 0.0216 0.0311 0.0351
Echinococcus granulosus mitogen activated protein kinase 3 0.0044 0.0049 0.0091
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0015 0.0005 0.0009
Echinococcus granulosus lipoxygenase domain containing protein 0.0029 0.0026 0.0048
Schistosoma mansoni carbonic anhydrase-related 0.0081 0.0106 0.0198
Trichomonas vaginalis glucosylceramidase, putative 0.0049 0.0056 0.0104
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0062 0.0076 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Onchocerca volvulus 0.0049 0.0057 0.0059
Onchocerca volvulus 0.0049 0.0057 0.0059
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0035 0.0036 0.0067
Echinococcus multilocularis thyroid hormone receptor alpha 0.0067 0.0084 0.0157
Onchocerca volvulus 0.0169 0.024 0.0252
Brugia malayi Cathepsin L-like precursor 0.0021 0.0013 0.0013
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0246 0.0357 0.0357
Leishmania major farnesyltransferase beta subunit 0.1584 0.2397 1
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0032 0.003 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.0051 0.006 0.0111
Loa Loa (eye worm) hypothetical protein 0.0028 0.0025 0.0028
Onchocerca volvulus 0.0418 0.0618 0.0649
Onchocerca volvulus 0.0049 0.0057 0.0059
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0057 0.0106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Plasmodium falciparum glutathione reductase 0.0038 0.004 0.0074
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0331 0.0487 0.0908
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0216 0.0311 0.058
Echinococcus granulosus lactate dehydrogenase a 0.0025 0.0021 0.0039
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0872 0.1311 0.1311
Trichomonas vaginalis glucosylceramidase, putative 0.0049 0.0056 0.0104
Brugia malayi aspartic protease BmAsp-2, identical 0.0034 0.0034 0.0034
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0057 0.0106
Brugia malayi Guanylyl cyclase protein 23 0.0016 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0078 0.0101 0.0422
Brugia malayi hypothetical protein 0.0049 0.0057 0.0057
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0145 0.0203 0.0229
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0038 0.004 0.0051
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Brugia malayi Pre-SET motif family protein 0.0053 0.0062 0.0062
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.1756 0.2658 0.4757
Echinococcus multilocularis tyrosine protein kinase shark 0.0077 0.01 0.0186
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0351 0.0517 0.0542
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0057 0.0106
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0032 0.003 0.0056
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0094 0.0125 0.0158
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.003 0.0056
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0351 0.0517 0.0656
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0062 0.0076 0.0096
Brugia malayi Latrophilin receptor protein 2 0.0046 0.0052 0.0052
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0095 0.0127 0.0236
Loa Loa (eye worm) hypothetical protein 0.0067 0.0085 0.0095
Trypanosoma brucei aldo/keto reductase, putative 0.002 0.0013 0.0052
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0055
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0044 0.0049 0.0203
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0021 0.0013 0.0025
Echinococcus multilocularis hyperpolarization activated cyclic 0.0022 0.0016 0.0029
Mycobacterium ulcerans polyketide synthase 0.3678 0.5587 0.7093
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Echinococcus multilocularis nmda type glutamate receptor 0.0015 0.0005 0.0009
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0216 0.0311 0.1297
Onchocerca volvulus 0.007 0.0088 0.0092
Schistosoma mansoni nAChR subunit 0.0095 0.0127 0.0236
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.023 0.0332 0.0619
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0062 0.0076 0.0096
Giardia lamblia Prenyltransferase 0.1584 0.2397 0.4472
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0351 0.0517 0.0656
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0015 0.0005 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0018 0.001 0.0018
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1808 0.2738 0.5109
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0035 0.0036 0.004
Loa Loa (eye worm) AGC/PKG protein kinase 0.0013 0.0001 0.0001
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0051 0.006 0.0112
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0039 0.0041 0.0076
Schistosoma mansoni P2X receptor subunit 0.0119 0.0164 0.0306
Trypanosoma brucei unspecified product 0.0019 0.001 0.0042
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0216 0.0311 0.1297
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0095 0.0127 0.0236
Trypanosoma cruzi aldo/keto reductase, putative 0.002 0.0013 0.0052
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0109 0.0148 0.0276
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0331 0.0487 0.0908
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0095 0.0127 0.0143
Leishmania major acyl carrier protein, putative 0.0351 0.0517 0.2156
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0035 0.0035 0.0065
Loa Loa (eye worm) hypothetical protein 0.0058 0.007 0.0079
Loa Loa (eye worm) hypothetical protein 0.0049 0.0057 0.0064
Plasmodium falciparum plasmepsin X 0.0034 0.0034 0.0062
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0035 0.0035 0.0145
Loa Loa (eye worm) hypothetical protein 0.0169 0.024 0.0271
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0044 0.0049 0.0203
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0035 0.0035 0.0065
Echinococcus multilocularis RUN 0.0029 0.0026 0.0048
Echinococcus multilocularis lactate dehydrogenase a 0.0025 0.0021 0.0039
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.1091 0.1645 0.2088
Onchocerca volvulus 0.0049 0.0057 0.0059
Echinococcus multilocularis p2X purinoceptor 4 0.0119 0.0164 0.0306

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) = 12.1 uM Cytotoxic concentration of the compound required to inhibit CEM cell proliferation by 50% ChEMBL. 10999474
CC50 (functional) = 12.1 uM Cytotoxic concentration of the compound required to inhibit CEM cell proliferation by 50% ChEMBL. 10999474
Log 1/EC50 (functional) 0 uM Effective concentration of the compound required to inhibit 50% of HIV-2 induced giant cell formation in CEM cell cultures; No data ChEMBL. 10999474
Log 1/EC50 (functional) = 1.4 uM Effective concentration of the compound required to inhibit 50% of HIV-1 induced giant cell formation in CEM cell cultures ChEMBL. 10999474
Log 1/EC50 (functional) = 1.4 uM Effective concentration of the compound required to inhibit 50% of HIV-1 induced giant cell formation in CEM cell cultures ChEMBL. 10999474

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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