Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tar DNA binding protein | 0.0073 | 0.1045 | 0.1045 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.1139 | 0.1202 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0022 | 0.0019 | 0.0021 |
Plasmodium falciparum | thioredoxin reductase | 0.0029 | 0.0175 | 0.0152 |
Onchocerca volvulus | 0.0022 | 0.0019 | 0.0045 | |
Schistosoma mansoni | kinase | 0.005 | 0.0577 | 0.0577 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.005 | 0.033 |
Mycobacterium tuberculosis | Probable reductase | 0.0194 | 0.3432 | 0.3619 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0078 | 0.1139 | 0.1202 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0019 | 0.0019 |
Onchocerca volvulus | Alhambra homolog | 0.003 | 0.019 | 0.0444 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0078 | 0.1139 | 0.1202 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0022 | 0.0019 | 0.0019 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1045 | 0.1045 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0194 | 0.3432 | 0.3619 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0019 | 0.0021 |
Brugia malayi | ecdysteroid receptor | 0.0022 | 0.0019 | 0.0021 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0022 | 0.0019 | 0.0021 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0078 | 0.1139 | 0.1139 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0019 | 0.0021 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0085 | 0.1275 | 0.8327 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0029 | 0.0175 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.2569 | 0.2569 |
Brugia malayi | nuclear hormone receptor | 0.0022 | 0.0019 | 0.0021 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0022 | 0.0019 | 0.0045 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1531 | 0.358 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0618 | 0.0679 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.005 | 0.0072 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1531 | 0.358 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0605 | 0.0605 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.0827 | 0.091 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0022 | 0.0019 | 0.0045 |
Echinococcus granulosus | expressed protein | 0.0035 | 0.0285 | 0.0285 |
Schistosoma mansoni | hypothetical protein | 0.0129 | 0.2141 | 0.2141 |
Mycobacterium ulcerans | lipase LipD | 0.0078 | 0.1139 | 0.1623 |
Echinococcus multilocularis | geminin | 0.0526 | 1 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0051 | 0.0605 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0019 | 0.0021 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0029 | 0.0175 | 0.114 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0098 | 0.1531 | 0.1684 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0099 | 0.1552 | 0.1552 |
Schistosoma mansoni | jumonji domain containing protein | 0.0079 | 0.1149 | 0.1149 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0019 | 0.0021 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0022 | 0.0019 | 0.0021 |
Brugia malayi | Thioredoxin reductase | 0.0085 | 0.1275 | 0.1402 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0022 | 0.0019 | 0.0021 |
Trypanosoma brucei | trypanothione reductase | 0.0085 | 0.1275 | 0.8327 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0175 | 0.0249 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0158 | 0.0158 |
Plasmodium falciparum | glutathione reductase | 0.0085 | 0.1275 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0098 | 0.1531 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.1139 | 0.2664 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0029 | 0.0175 | 0.0408 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1139 | 0.1253 |
Giardia lamblia | Kinase, PLK | 0.0098 | 0.1531 | 1 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0158 | 0.0173 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0022 | 0.0019 | 0.0021 |
Echinococcus granulosus | tumor protein p63 | 0.0339 | 0.6295 | 0.6295 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0022 | 0.0019 | 0.0019 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0175 | 0.114 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0182 | 0.02 |
Echinococcus multilocularis | tumor protein p63 | 0.0339 | 0.6295 | 0.6295 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0073 | 0.1045 | 0.1149 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0029 | 0.0175 | 0.0249 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0098 | 0.1531 | 0.2181 |
Giardia lamblia | PHD finger protein 15 | 0.003 | 0.019 | 0.124 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.1139 | 0.1202 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0129 | 0.2141 | 0.2141 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0029 | 0.0175 | 0.5 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0034 | 0.0269 | 0.0383 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0022 | 0.0019 | 0.0019 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0078 | 0.1139 | 0.7441 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.1139 | 0.1202 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0029 | 0.0175 | 0.0152 |
Trichomonas vaginalis | esterase, putative | 0.0078 | 0.1139 | 0.2664 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0068 | 0.0933 | 0.0933 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0019 | 0.0021 |
Echinococcus multilocularis | peregrin | 0.003 | 0.019 | 0.019 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0078 | 0.1139 | 0.1623 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0375 | 0.7022 | 0.7022 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0029 | 0.0175 | 0.0152 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0102 | 0.1604 | 0.1604 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0068 | 0.0933 | 0.0933 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0029 | 0.0175 | 0.0249 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0029 | 0.0175 | 0.0249 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0316 | 0.0316 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1139 | 0.1253 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.005 | 0.0118 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0424 | 0.0424 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0194 | 0.3432 | 0.3619 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0022 | 0.0019 | 0.0019 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.005 | 0.033 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0022 | 0.0019 | 0.0021 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0316 | 0.0316 |
Plasmodium falciparum | glutathione reductase | 0.0029 | 0.0175 | 0.0152 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0022 | 0.0019 | 0.0021 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.2569 | 0.2569 |
Loa Loa (eye worm) | RNA binding protein | 0.0073 | 0.1045 | 0.1149 |
Brugia malayi | RNA binding protein | 0.0073 | 0.1045 | 0.1149 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1531 | 0.358 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0375 | 0.7022 | 0.7022 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.019 | 0.019 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0316 | 0.0347 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0035 | 0.0285 | 0.0314 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0029 | 0.0175 | 0.0249 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0099 | 0.1558 | 0.1713 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0424 | 0.0424 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0029 | 0.0175 | 0.114 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0022 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0162 | 0.2796 | 0.3075 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0019 | 0.0019 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.019 | 0.027 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.1139 | 0.2664 |
Brugia malayi | Pre-SET motif family protein | 0.0208 | 0.3708 | 0.4078 |
Trypanosoma brucei | polo-like protein kinase | 0.0098 | 0.1531 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.1558 | 0.1558 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0111 | 0.1782 | 0.196 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0182 | 0.0182 |
Schistosoma mansoni | hypothetical protein | 0.0526 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0098 | 0.1531 | 0.1531 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0216 | 0.3861 | 0.4071 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0375 | 0.7022 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1531 | 0.358 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.019 | 0.0209 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0375 | 0.7022 | 1 |
Brugia malayi | beta-lactamase | 0.0078 | 0.1139 | 0.1253 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.1558 | 0.1558 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0375 | 0.7022 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0029 | 0.0175 | 0.0152 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0158 | 0.103 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0375 | 0.7022 | 0.7022 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.019 | 0.0209 |
Schistosoma mansoni | nuclear hormone receptor | 0.0022 | 0.0019 | 0.0019 |
Brugia malayi | follicle stimulating hormone receptor | 0.048 | 0.9093 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0022 | 0.0019 | 0.0021 |
Schistosoma mansoni | coup transcription factor | 0.0022 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.2796 | 0.3075 |
Onchocerca volvulus | 0.0078 | 0.1139 | 0.2664 | |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0102 | 0.1604 | 0.1604 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0022 | 0.0019 | 0.0019 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.0386 | 0.0386 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0098 | 0.1531 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1139 | 0.1253 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.1139 | 0.2664 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0158 | 0.0173 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.1558 | 0.1558 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.0269 | 0.1757 |
Brugia malayi | TAR-binding protein | 0.0073 | 0.1045 | 0.1149 |
Onchocerca volvulus | 0.0237 | 0.4277 | 1 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0078 | 0.1139 | 0.1202 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0208 | 0.3708 | 0.4078 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.019 | 0.019 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0022 | 0.0019 | 0.0019 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0022 | 0.0019 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0019 | 0.0021 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0029 | 0.0175 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0306 | 0.5639 | 0.5639 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0162 | 0.2796 | 0.3075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0022 | 0.0019 | 0.0021 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.019 | 0.027 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0022 | 0.0019 | 0.0021 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0022 | 0.0019 | 0.0021 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0098 | 0.1531 | 0.1531 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0085 | 0.1275 | 0.1402 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0605 | 0.0605 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0175 | 0.114 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.1139 | 0.1253 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0175 | 0.0249 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0375 | 0.7022 | 0.7405 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0029 | 0.0175 | 0.114 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0086 | 0.1285 | 0.1285 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0098 | 0.1531 | 0.358 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0375 | 0.7022 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0019 | 0.0021 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0182 | 0.0182 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0375 | 0.7022 | 0.7022 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0022 | 0.0019 | 0.0019 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0386 | 0.2521 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.0551 | 0.1289 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.1139 | 0.2664 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1531 | 0.358 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0182 | 0.0215 |
Onchocerca volvulus | 0.0078 | 0.1139 | 0.2664 | |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0605 | 0.0605 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0022 | 0.0019 | 0.0021 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0306 | 0.5639 | 0.6201 |
Echinococcus granulosus | FTZ F1 alpha | 0.0022 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0022 | 0.0019 | 0.0021 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0034 | 0.0269 | 0.1757 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.005 | 0.0118 |
Trichomonas vaginalis | set domain proteins, putative | 0.0237 | 0.4277 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1139 | 0.1253 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0029 | 0.0175 | 0.0175 |
Brugia malayi | steroid hormone receptor | 0.0022 | 0.0019 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0111 | 0.1782 | 0.1782 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0175 | 0.114 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0022 | 0.002 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0933 | 0.1026 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0194 | 0.3432 | 0.889 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.019 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1139 | 0.1253 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.0269 | 0.1757 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.019 | 0.0209 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0029 | 0.0175 | 0.114 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0316 | 0.0316 |
Brugia malayi | nuclear receptor NHR-88 | 0.0022 | 0.0019 | 0.0021 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0572 | 0.0572 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0375 | 0.7022 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.1558 | 0.1558 |
Loa Loa (eye worm) | beta-lactamase | 0.0078 | 0.1139 | 0.1253 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0078 | 0.1139 | 0.1202 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.0551 | 0.1289 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0098 | 0.1531 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0078 | 0.1139 | 0.1623 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0019 | 0.0021 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.0102 | 0.1604 | 0.1604 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0102 | 0.1604 | 0.1604 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0022 | 0.0019 | 0.0021 |
Plasmodium falciparum | thioredoxin reductase | 0.0085 | 0.1275 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0216 | 0.3861 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0386 | 0.2521 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0182 | 0.0182 |
Brugia malayi | glutathione reductase | 0.0085 | 0.1275 | 0.1402 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.015 | 0.2569 | 0.2569 |
Treponema pallidum | NADH oxidase | 0.0029 | 0.0175 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0022 | 0.0019 | 0.0019 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0034 | 0.0269 | 0.0383 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0216 | 0.3861 | 0.4071 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0022 | 0.0019 | 0.0019 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0078 | 0.1139 | 0.1202 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0158 | 0.0158 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0175 | 0.114 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.019 | 0.019 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0605 | 0.0605 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.1558 | 0.1558 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.1202 | 0.1322 |
Plasmodium vivax | glutathione reductase, putative | 0.0085 | 0.1275 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0022 | 0.0019 | 0.0019 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0022 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0022 | 0.0019 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0605 | 0.0605 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0316 | 0.0347 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0175 | 0.114 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0605 | 0.0605 |
Toxoplasma gondii | thioredoxin reductase | 0.0085 | 0.1275 | 0.1816 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0034 | 0.0269 | 0.1757 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0022 | 0.0019 | 0.0019 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.019 | 0.0288 |
Plasmodium vivax | hypothetical protein, conserved | 0.0078 | 0.1139 | 0.8786 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0085 | 0.1275 | 0.1344 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0078 | 0.1139 | 0.1253 |
Echinococcus multilocularis | expressed protein | 0.0035 | 0.0285 | 0.0285 |
Schistosoma mansoni | hypothetical protein | 0.0526 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1531 | 0.358 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.1139 | 0.1253 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0572 | 0.0629 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0194 | 0.3432 | 0.3619 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1139 | 0.1253 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0078 | 0.1139 | 0.1202 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0129 | 0.2141 | 0.2141 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0182 | 0.0182 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.1558 | 0.1558 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0051 | 0.0605 | 0.0666 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.1558 | 0.1558 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.005 | 0.0118 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0085 | 0.1275 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0386 | 0.2521 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.019 | 0.0288 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0022 | 0.0019 | 0.0021 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0102 | 0.1604 | 0.1604 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0029 | 0.0175 | 0.114 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0194 | 0.3432 | 0.3619 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0158 | 0.0225 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0086 | 0.1285 | 0.1285 |
Toxoplasma gondii | ABC1 family protein | 0.0078 | 0.1139 | 0.1623 |
Schistosoma mansoni | rotamase | 0.0035 | 0.0285 | 0.0285 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0029 | 0.0175 | 0.0152 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0022 | 0.0019 | 0.0019 |
Trichomonas vaginalis | rotamase, putative | 0.0035 | 0.0285 | 0.0667 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.1139 | 0.1139 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1045 | 0.1045 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0022 | 0.0019 | 0.0019 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0605 | 0.0605 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0029 | 0.0175 | 0.114 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0068 | 0.0933 | 0.2182 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0051 | 0.0605 | 0.0666 |
Brugia malayi | hypothetical protein | 0.004 | 0.0386 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0182 | 0.02 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0029 | 0.0175 | 0.0175 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0022 | 0.0019 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.1782 | 0.196 |
Onchocerca volvulus | 0.005 | 0.0572 | 0.1338 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1045 | 0.1045 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0078 | 0.1139 | 0.1623 |
Loa Loa (eye worm) | glutathione reductase | 0.0085 | 0.1275 | 0.1402 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0078 | 0.1139 | 0.1202 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0182 | 0.0182 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1045 | 0.1045 |
Brugia malayi | Melibiase family protein | 0.0068 | 0.0933 | 0.1026 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0022 | 0.0019 | 0.0019 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0182 | 0.0182 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0073 | 0.1045 | 0.1149 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0216 | 0.3861 | 0.4071 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1531 | 0.358 |
Echinococcus granulosus | GPCR family 2 | 0.0051 | 0.0605 | 0.0605 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0102 | 0.1604 | 0.1604 |
Echinococcus granulosus | snurportin 1 | 0.0306 | 0.5639 | 0.5639 |
Echinococcus multilocularis | GPCR, family 2 | 0.0051 | 0.0605 | 0.0605 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0098 | 0.1531 | 0.1531 |
Mycobacterium leprae | conserved hypothetical protein | 0.0078 | 0.1139 | 0.2951 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0194 | 0.3432 | 0.3619 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0099 | 0.1552 | 0.1552 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0078 | 0.1139 | 0.1253 |
Onchocerca volvulus | 0.003 | 0.0182 | 0.0425 | |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.0269 | 0.0629 |
Mycobacterium ulcerans | hypothetical protein | 0.0078 | 0.1139 | 0.1623 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.1139 | 0.2664 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0022 | 0.0019 | 0.0021 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0029 | 0.0175 | 0.0184 |
Toxoplasma gondii | melibiase subfamily protein | 0.0102 | 0.1604 | 0.2284 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0029 | 0.0175 | 0.0408 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0175 | 0.114 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0162 | 0.2796 | 0.3075 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0102 | 0.1604 | 0.1604 |
Echinococcus granulosus | tar DNA binding protein | 0.0073 | 0.1045 | 0.1045 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0019 | 0.0019 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0029 | 0.0175 | 0.0249 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0605 | 0.0605 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0022 | 0.0019 | 0.0021 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0316 | 0.0316 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0022 | 0.002 | 0.0022 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.0386 | 0.0386 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0022 | 0.0019 | 0.0019 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.1045 | 0.1045 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0019 | 0.0019 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.0386 | 0.0386 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0035 | 0.0285 | 0.0314 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0029 | 0.0175 | 0.0249 |
Echinococcus granulosus | peregrin | 0.003 | 0.019 | 0.019 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0386 | 0.2521 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0022 | 0.0019 | 0.0021 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.1139 | 0.7441 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.1139 | 0.7441 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.016 | 0.016 |
Schistosoma mansoni | hypothetical protein | 0.0306 | 0.5639 | 0.5639 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0029 | 0.0175 | 0.0249 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0022 | 0.0019 | 0.0021 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0099 | 0.1558 | 0.1713 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.1139 | 0.1139 |
Onchocerca volvulus | 0.0078 | 0.1139 | 0.2664 | |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0029 | 0.0175 | 0.0192 |
Mycobacterium leprae | Probable lipase LipE | 0.0078 | 0.1139 | 0.2951 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0029 | 0.0175 | 0.0175 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0022 | 0.0019 | 0.0021 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0098 | 0.1531 | 0.1684 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0182 | 0.0259 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0158 | 0.103 |
Brugia malayi | jmjC domain containing protein | 0.0099 | 0.1552 | 0.1707 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0022 | 0.0019 | 0.0019 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0285 | 0.0667 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0182 | 0.0182 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0022 | 0.0019 | 0.0019 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | TAR-binding protein | 0.0073 | 0.1045 | 0.1149 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0605 | 0.0666 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.05 | 0.9482 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.048 | 0.9093 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0022 | 0.0019 | 0.0021 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.019 | 0.0209 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0022 | 0.0019 | 0.0019 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0029 | 0.0175 | 0.114 |
Leishmania major | trypanothione reductase | 0.0085 | 0.1275 | 0.1816 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0029 | 0.0175 | 0.114 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0386 | 0.0386 |
Mycobacterium ulcerans | beta-lactamase | 0.0078 | 0.1139 | 0.1623 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0019 | 0.0021 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0078 | 0.1139 | 0.1139 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 12 % | DNDI: Inhibition of Human African Trypanosomiasis, SBRI 427, in vitro at 2 ug.mL-1 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.