Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0132 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.3412 | 0.3412 |
Schistosoma mansoni | tar DNA-binding protein | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0132 | 1 | 1 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.1515 | 0.0229 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.2073 | 0.0873 |
Echinococcus granulosus | tar DNA binding protein | 0.0132 | 1 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0175 | 0.0175 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.1515 | 0.1476 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.1515 | 0.5 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.1515 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.1316 | 0.1316 |
Echinococcus multilocularis | tar DNA binding protein | 0.0132 | 1 | 1 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.1515 | 0.1363 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0103 | 0.7556 | 0.7545 |
Schistosoma mansoni | tar DNA-binding protein | 0.0132 | 1 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.1316 | 0.1276 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.1515 | 0.1363 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.1316 | 0.1161 |
Echinococcus multilocularis | musashi | 0.0029 | 0.1316 | 0.1276 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0132 | 1 | 1 |
Echinococcus multilocularis | lamin | 0.0029 | 0.1316 | 0.1276 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0065 | 0.4342 | 0.4342 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0044 | 0.2555 | 0.2521 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0132 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.1316 | 0.1276 |
Echinococcus granulosus | jumonji domain containing protein | 0.0044 | 0.2555 | 0.2521 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0045 | 0.0045 |
Echinococcus granulosus | peregrin | 0.0031 | 0.1515 | 0.1476 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.1271 | 0.1271 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.1515 | 0.1515 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1515 | 0.0229 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0038 | 0.2073 | 0.2038 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0103 | 0.7556 | 0.7545 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.1316 | 0.1316 |
Brugia malayi | TAR-binding protein | 0.0132 | 1 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.1515 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.2073 | 0.2073 |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0.1515 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0082 | 0.5768 | 0.5127 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.1316 | 0.1161 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.1316 | 0.1316 |
Loa Loa (eye worm) | TAR-binding protein | 0.0132 | 1 | 1 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.1515 | 0.1476 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.1515 | 0.1515 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.1316 | 0.1276 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.1515 | 0.5 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0038 | 0.2073 | 0.2038 |
Echinococcus granulosus | lamin | 0.0029 | 0.1316 | 0.1276 |
Schistosoma mansoni | tar DNA-binding protein | 0.0132 | 1 | 1 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.1515 | 0.1476 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.2073 | 0.0873 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0.1515 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.2073 | 0.1932 |
Brugia malayi | jmjC domain containing protein | 0.0103 | 0.7556 | 0.7512 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.