Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | DNA polymerase eta, putative | 0.0035 | 0.5597 | 0.4775 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.1847 | 0.1904 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.005 | 0.9701 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 1 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.005 | 0.9701 | 0.9633 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 1 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.005 | 0.9701 | 0.9633 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.1847 | 0.1904 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.1847 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 1 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 0.1847 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0022 | 0.1847 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.005 | 0.9701 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0022 | 0.1847 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0035 | 0.5597 | 0.5 |
Echinococcus granulosus | dna polymerase eta | 0.005 | 0.9701 | 0.9633 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0022 | 0.1847 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.005 | 0.9701 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.9701 | 0.9633 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0022 | 0.1847 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Echinococcus multilocularis | dna polymerase eta | 0.005 | 0.9701 | 0.9633 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0035 | 0.5597 | 0.4775 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.1847 | 0.1904 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.1847 | 0.1904 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.1847 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0022 | 0.1847 | 0.5 |
Trypanosoma brucei | unspecified product | 0.0022 | 0.1847 | 0.1904 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.