Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0032 | 0.0065 | 0.0417 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.003 | 0.0056 | 0.1203 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0282 | 0.1828 | 0.3009 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0781 | 0.1285 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0032 | 0.0065 | 0.0059 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0261 | 0.1678 | 0.2763 |
Brugia malayi | hypothetical protein | 0.032 | 0.2097 | 0.3453 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0317 | 0.1516 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0199 | 0.1244 | 0.1244 |
Toxoplasma gondii | thioredoxin reductase | 0.0088 | 0.0462 | 0.3301 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0032 | 0.0065 | 0.0059 |
Brugia malayi | beta-lactamase | 0.0221 | 0.1401 | 0.2306 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0636 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.2808 | 0.4623 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.000004799 | 0.0000079013 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0032 | 0.0065 | 0.0313 |
Onchocerca volvulus | 0.008 | 0.0405 | 0.0574 | |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0032 | 0.0065 | 0.0417 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0133 | 0.0781 | 0.0781 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.0781 | 0.0781 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0221 | 0.1401 | 0.1401 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0183 | 0.1132 | 0.1132 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0038 | 0.0106 | 0.0106 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0127 | 0.0736 | 0.5253 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.008 | 0.0405 | 0.1938 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0038 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1401 | 0.2306 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0067 | 0.0317 | 0.1516 |
Brugia malayi | Cytochrome P450 family protein | 0.0051 | 0.0204 | 0.0335 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0032 | 0.0065 | 0.0059 |
Mycobacterium tuberculosis | Conserved protein | 0.0221 | 0.1401 | 0.1423 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Loa Loa (eye worm) | glutathione reductase | 0.0088 | 0.0462 | 0.0761 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0031 | 0.0057 | 0.0273 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0032 | 0.0065 | 0.0059 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0133 | 0.0781 | 0.1285 |
Brugia malayi | Bromodomain containing protein | 0.0118 | 0.067 | 0.1103 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0056 | 0.008 |
Trypanosoma cruzi | ISWI complex protein | 0.0047 | 0.0173 | 0.0826 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0223 | 0.1415 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0059 | 0.026 | 0.026 |
Brugia malayi | AMP-binding enzyme family protein | 0.008 | 0.0405 | 0.0667 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Trypanosoma brucei | glucosidase, putative | 0.0038 | 0.0106 | 0.0508 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0059 | 0.026 | 0.0375 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0133 | 0.0781 | 0.1285 |
Schistosoma mansoni | tar DNA-binding protein | 0.041 | 0.2731 | 0.2731 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0317 | 0.1516 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0112 | 0.0633 | 0.3027 |
Plasmodium falciparum | glutathione reductase | 0.0088 | 0.0462 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0056 | 0.024 | 0.0237 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0127 | 0.0736 | 0.0736 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0032 | 0.0065 | 0.0059 |
Loa Loa (eye worm) | cytochrome P450 | 0.0032 | 0.0065 | 0.0108 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0031 | 0.0057 | 0.0273 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0112 | 0.0633 | 0.0638 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0112 | 0.0633 | 0.0912 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0031 | 0.0057 | 0.0082 |
Brugia malayi | hypothetical protein | 0.0113 | 0.0636 | 0.1048 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0056 | 0.008 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0223 | 0.1415 | 0.1437 |
Onchocerca volvulus | 0.0221 | 0.1401 | 0.2011 | |
Trichomonas vaginalis | mercuric reductase, putative | 0.0031 | 0.0057 | 0.0082 |
Trypanosoma brucei | trypanothione reductase | 0.0088 | 0.0462 | 0.2212 |
Loa Loa (eye worm) | hypothetical protein | 0.0288 | 0.187 | 0.3078 |
Plasmodium vivax | importin-beta 2, putative | 0.0059 | 0.0254 | 0.1815 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.041 | 0.2731 | 0.4496 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0112 | 0.0633 | 0.994 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.008 | 0.0405 | 0.6365 |
Brugia malayi | Bromodomain containing protein | 0.023 | 0.1463 | 0.2408 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0179 | 0.1104 | 0.1104 |
Mycobacterium tuberculosis | Conserved protein | 0.0221 | 0.1401 | 0.1423 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0183 | 0.1132 | 0.1132 |
Echinococcus granulosus | zinc finger protein | 0.006 | 0.0265 | 0.0265 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0112 | 0.0633 | 0.4487 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Brugia malayi | 6-phosphofructokinase | 0.0112 | 0.0633 | 0.1041 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0106 | 0.0508 |
Schistosoma mansoni | hypothetical protein | 0.0625 | 0.4243 | 0.4243 |
Brugia malayi | RNA, U transporter 1 | 0.0166 | 0.1014 | 0.167 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0088 | 0.0462 | 0.0761 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0106 | 0.167 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0127 | 0.0736 | 0.0736 |
Echinococcus multilocularis | tar DNA binding protein | 0.041 | 0.2731 | 0.2731 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0151 | 0.0906 | 0.4335 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0059 | 0.026 | 0.1245 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0051 | 0.0204 | 0.0975 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0106 | 0.0508 |
Brugia malayi | Thioredoxin reductase | 0.0088 | 0.0462 | 0.0761 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0112 | 0.0633 | 0.0633 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0112 | 0.0633 | 0.0912 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0023 | 0.0007 | 0.0053 |
Trypanosoma brucei | cytochrome P450, putative | 0.0051 | 0.0204 | 0.0975 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0201 | 0.1257 | 0.1276 |
Plasmodium vivax | SET domain protein, putative | 0.0127 | 0.0736 | 0.5253 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0023 | 0.0007 | 0.0035 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0059 | 0.026 | 0.4089 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0059 | 0.026 | 0.1814 |
Brugia malayi | RNA binding protein | 0.041 | 0.2731 | 0.4497 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0221 | 0.1401 | 0.1423 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0201 | 0.1257 | 0.1276 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0065 | 0.0065 |
Schistosoma mansoni | alpha glucosidase | 0.0038 | 0.0106 | 0.0106 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0282 | 0.1828 | 0.1828 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.0636 | 0.0636 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0032 | 0.0065 | 0.0059 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0221 | 0.1401 | 0.2306 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0007 | 0.0012 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0151 | 0.0906 | 0.4335 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.1104 | 0.1818 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0031 | 0.0057 | 0.0273 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1442 | 1 | 1 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0112 | 0.0633 | 0.3027 |
Schistosoma mansoni | bromodomain containing protein | 0.0194 | 0.121 | 0.121 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0221 | 0.1401 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0023 | 0.0007 | 0.0035 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0032 | 0.0065 | 0.0417 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0221 | 0.1401 | 0.1401 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0088 | 0.0462 | 0.3301 |
Mycobacterium ulcerans | hypothetical protein | 0.0168 | 0.1026 | 0.7311 |
Mycobacterium tuberculosis | Conserved protein | 0.0221 | 0.1401 | 0.1423 |
Plasmodium falciparum | thioredoxin reductase | 0.0088 | 0.0462 | 1 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0023 | 0.0007 | 0.0053 |
Toxoplasma gondii | exonuclease III APE | 0.0059 | 0.026 | 0.1857 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0201 | 0.1257 | 0.8878 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0113 | 0.0636 | 0.0636 |
Plasmodium falciparum | glutathione reductase | 0.0031 | 0.0057 | 0.1233 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.003 | 0.0056 | 0.0397 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0051 | 0.0204 | 0.0335 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.003 | 0.0056 | 0.0874 |
Leishmania major | cytochrome p450-like protein | 0.0051 | 0.0204 | 0.0975 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0088 | 0.0462 | 0.0465 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0032 | 0.0065 | 0.0417 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0054 | 0.0224 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0263 | 0.0433 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0032 | 0.0065 | 0.0417 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.008 | 0.0405 | 0.2854 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0031 | 0.0057 | 0.0273 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0221 | 0.1401 | 0.1423 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.1414 | 0.98 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0017 | 0.0371 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0032 | 0.0065 | 0.0313 |
Toxoplasma gondii | propionate-CoA ligase | 0.0023 | 0.0007 | 0.0053 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0221 | 0.1401 | 0.1423 |
Schistosoma mansoni | tar DNA-binding protein | 0.041 | 0.2731 | 0.2731 |
Brugia malayi | Pre-SET motif family protein | 0.0885 | 0.6074 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0201 | 0.1257 | 0.1276 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0023 | 0.0007 | 0.0035 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0319 | 0.209 | 1 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.003 | 0.0056 | 0.0397 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0056 | 0.024 | 0.0237 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0059 | 0.026 | 0.5627 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.006 | 0.0263 | 0.1833 |
Brugia malayi | beta-lactamase family protein | 0.0221 | 0.1401 | 0.2306 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.0781 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.0764 | 0.1257 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0056 | 0.008 |
Onchocerca volvulus | 0.0098 | 0.0531 | 0.0755 | |
Schistosoma mansoni | importin beta-1 | 0.0059 | 0.0254 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0263 | 0.0433 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0017 | 0.0082 |
Brugia malayi | Cytochrome P450 family protein | 0.0051 | 0.0204 | 0.0335 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0032 | 0.0065 | 0.0065 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0052 | 0.0211 | 0.0211 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0113 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0007 | 0.0012 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0421 | 0.2808 | 0.4623 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.008 | 0.0405 | 0.6365 |
Toxoplasma gondii | hypothetical protein | 0.0051 | 0.0205 | 0.1461 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0112 | 0.0633 | 0.994 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0112 | 0.0633 | 0.1041 |
Schistosoma mansoni | hypothetical protein | 0.0913 | 0.6275 | 0.6275 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.008 | 0.0405 | 0.2854 |
Schistosoma mansoni | hypothetical protein | 0.0913 | 0.6275 | 0.6275 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0221 | 0.1401 | 0.6703 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0221 | 0.1401 | 0.6703 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0031 | 0.0057 | 0.1233 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0636 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0059 | 0.026 | 0.1245 |
Schistosoma mansoni | alpha-glucosidase | 0.0145 | 0.0867 | 0.0867 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0032 | 0.0065 | 0.0059 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0885 | 0.6074 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0106 | 0.0153 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0221 | 0.1401 | 0.2306 |
Onchocerca volvulus | 0.0221 | 0.1401 | 0.2011 | |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0032 | 0.0065 | 0.0417 |
Leishmania major | cytochrome p450-like protein | 0.0032 | 0.0065 | 0.0313 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0051 | 0.0204 | 0.0975 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0059 | 0.026 | 0.1245 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0317 | 0.1516 |
Loa Loa (eye worm) | RNA binding protein | 0.041 | 0.2731 | 0.4496 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0319 | 0.209 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.008 | 0.0405 | 0.2854 |
Schistosoma mansoni | tar DNA-binding protein | 0.041 | 0.2731 | 0.2731 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0017 | 0.0028 |
Brugia malayi | TAR-binding protein | 0.041 | 0.2731 | 0.4497 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0023 | 0.0007 | 0.0116 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0023 | 0.0007 | 0.0011 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0133 | 0.0781 | 0.0781 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0069 | 0.0329 | 0.0329 |
Mycobacterium ulcerans | beta-lactamase | 0.0221 | 0.1401 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0031 | 0.0057 | 0.0407 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0032 | 0.0065 | 0.0417 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0106 | 0.0153 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0023 | 0.0007 | 0.0053 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0032 | 0.0065 | 0.0417 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0097 | 0.0526 | 0.0866 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0288 | 0.187 | 0.3078 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1442 | 1 | 1 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0112 | 0.0633 | 0.4441 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0636 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0122 | 0.0703 | 0.0703 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0059 | 0.026 | 0.026 |
Schistosoma mansoni | ap endonuclease | 0.0059 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1401 | 0.2306 |
Mycobacterium ulcerans | hypothetical protein | 0.0221 | 0.1401 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.0671 | 0.1105 |
Schistosoma mansoni | hypothetical protein | 0.0288 | 0.187 | 0.187 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0032 | 0.0065 | 0.0417 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0221 | 0.1401 | 0.202 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0199 | 0.1244 | 0.1244 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0032 | 0.0065 | 0.0059 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0056 | 0.008 |
Echinococcus multilocularis | tumor protein p63 | 0.0351 | 0.2311 | 0.2311 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0056 | 0.024 | 0.0237 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0032 | 0.0065 | 0.0059 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0169 | 0.1033 | 0.17 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0059 | 0.026 | 0.0258 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0059 | 0.0254 | 0.1217 |
Schistosoma mansoni | ap endonuclease | 0.0059 | 0.026 | 0.026 |
Schistosoma mansoni | zinc finger protein | 0.006 | 0.0265 | 0.0265 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0007 | 0.0012 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0032 | 0.0065 | 0.0313 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0112 | 0.0633 | 0.994 |
Brugia malayi | Importin beta-1 subunit | 0.0059 | 0.0254 | 0.0419 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0032 | 0.0065 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0263 | 0.0433 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0288 | 0.0288 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0127 | 0.0736 | 0.0736 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0007 | 0.0012 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.1033 | 0.1033 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0169 | 0.1033 | 0.1033 |
Trichomonas vaginalis | esterase, putative | 0.0221 | 0.1401 | 0.202 |
Onchocerca volvulus | 0.0127 | 0.0736 | 0.1052 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.008 | 0.0405 | 0.2854 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0168 | 0.1026 | 0.104 |
Brugia malayi | glutathione reductase | 0.0088 | 0.0462 | 0.0761 |
Schistosoma mansoni | cytochrome P450 | 0.0032 | 0.0065 | 0.0065 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0221 | 0.1401 | 0.1423 |
Treponema pallidum | NADH oxidase | 0.0031 | 0.0057 | 0.0024 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0031 | 0.0057 | 0.0407 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0421 | 0.2808 | 0.4623 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0405 | 0.0667 |
Leishmania major | hypothetical protein, conserved | 0.0047 | 0.0173 | 0.0826 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1401 | 0.2306 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0063 | 0.0288 | 0.0474 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0221 | 0.1401 | 0.1423 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0023 | 0.0007 | 0.0007 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0106 | 0.0759 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0221 | 0.1401 | 0.202 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0059 | 0.026 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0031 | 0.0057 | 0.0273 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0317 | 0.1516 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0031 | 0.0057 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0254 | 0.0419 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0031 | 0.0057 | 0.1233 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0038 | 0.0106 | 0.0175 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0263 | 0.0433 |
Mycobacterium tuberculosis | Probable reductase | 0.0201 | 0.1257 | 0.1276 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0106 | 0.0153 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0151 | 0.0906 | 0.4335 |
Echinococcus multilocularis | 0.0032 | 0.0065 | 0.0065 | |
Brugia malayi | AMP-binding enzyme family protein | 0.008 | 0.0405 | 0.0667 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0023 | 0.0007 | 0.0035 |
Echinococcus granulosus | tar DNA binding protein | 0.041 | 0.2731 | 0.2731 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0223 | 0.1415 | 0.1437 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.0781 | 0.0781 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0636 | 1 |
Mycobacterium leprae | putative cytochrome p450 | 0.0032 | 0.0065 | 0.0413 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0261 | 0.1678 | 0.2763 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1401 | 0.2306 |
Loa Loa (eye worm) | TAR-binding protein | 0.041 | 0.2731 | 0.4496 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0032 | 0.0065 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0722 | 0.1189 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0047 | 0.0176 | 0.0254 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0088 | 0.0462 | 0.2212 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0023 | 0.0007 | 0.0035 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0023 | 0.0007 | 0.0012 |
Schistosoma mansoni | alpha-glucosidase | 0.0145 | 0.0867 | 0.0867 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0031 | 0.0057 | 0.0356 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0282 | 0.1828 | 0.1828 |
Brugia malayi | phosphofructokinase | 0.0112 | 0.0633 | 0.1041 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0017 | 0.0082 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0112 | 0.0633 | 0.3027 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0199 | 0.1244 | 0.8875 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0047 | 0.0176 | 0.0254 |
Onchocerca volvulus | 0.1007 | 0.6935 | 1 | |
Echinococcus multilocularis | geminin | 0.0913 | 0.6275 | 0.6275 |
Onchocerca volvulus | 0.0051 | 0.0204 | 0.0283 | |
Brugia malayi | Cytochrome P450 family protein | 0.0097 | 0.0526 | 0.0866 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.003 | 0.0056 | 0.0397 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.008 | 0.0405 | 0.1938 |
Mycobacterium leprae | Probable lipase LipE | 0.0221 | 0.1401 | 0.9899 |
Mycobacterium leprae | conserved hypothetical protein | 0.0221 | 0.1401 | 0.9899 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0201 | 0.1257 | 0.1276 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0169 | 0.1033 | 0.17 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0051 | 0.0204 | 0.0335 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0112 | 0.0633 | 0.1041 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0032 | 0.0065 | 0.0417 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0023 | 0.0007 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0173 | 0.0173 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0199 | 0.1244 | 0.1263 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0199 | 0.1244 | 0.1244 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.008 | 0.0405 | 0.2854 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0059 | 0.026 | 0.3546 |
Brugia malayi | 6-phosphofructokinase | 0.0112 | 0.0633 | 0.1041 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0056 | 0.024 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0017 | 0.0028 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0158 | 0.0757 |
Loa Loa (eye worm) | phosphofructokinase | 0.0112 | 0.0633 | 0.1041 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0158 | 0.0757 |
Loa Loa (eye worm) | oxidoreductase | 0.0023 | 0.0007 | 0.0012 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0317 | 0.1516 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0055 | 0.0227 | 0.1087 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0059 | 0.026 | 0.0428 |
Leishmania major | importin beta-1 subunit, putative | 0.0047 | 0.0176 | 0.0844 |
Loa Loa (eye worm) | beta-lactamase | 0.0221 | 0.1401 | 0.2306 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0032 | 0.0065 | 0.0417 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0032 | 0.0065 | 0.0417 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.008 | 0.0405 | 0.1938 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0113 | 0.0636 | 0.0636 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.003 | 0.0056 | 0.1203 |
Schistosoma mansoni | tar DNA-binding protein | 0.041 | 0.2731 | 0.2731 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0059 | 0.026 | 0.1245 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0179 | 0.1104 | 0.1104 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.006 | 0.0263 | 0.1876 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0204 | 0.0335 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0221 | 0.1401 | 0.1423 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0032 | 0.0065 | 0.0059 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0032 | 0.0065 | 0.0059 |
Leishmania major | cytochrome p450-like protein | 0.0032 | 0.0065 | 0.0313 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0221 | 0.1401 | 0.202 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0051 | 0.0204 | 0.0335 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0282 | 0.1828 | 0.1828 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0106 | 0.0153 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0223 | 0.1415 | 0.1437 |
Toxoplasma gondii | 6-phosphofructokinase | 0.003 | 0.0056 | 0.0397 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0038 | 0.0106 | 0.0153 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0201 | 0.1257 | 0.1276 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0112 | 0.0633 | 0.0633 |
Brugia malayi | AMP-binding enzyme family protein | 0.008 | 0.0405 | 0.0667 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0047 | 0.0176 | 0.0844 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0017 | 0.0371 |
Echinococcus granulosus | tumor protein p63 | 0.0351 | 0.2311 | 0.2311 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.008 | 0.0405 | 0.6365 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0007 | 0.0012 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0069 | 0.0329 | 0.0329 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0282 | 0.1828 | 0.1828 |
Plasmodium falciparum | importin beta, putative | 0.0059 | 0.0254 | 0.55 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.003 | 0.0056 | 0.0397 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0038 | 0.0106 | 0.0175 |
Brugia malayi | Pre-SET motif family protein | 0.0127 | 0.0736 | 0.1212 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0112 | 0.0633 | 0.0912 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0263 | 0.0433 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0023 | 0.0007 | 0.0035 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0032 | 0.0065 | 0.0313 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0017 | 0.0082 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0023 | 0.0007 | 0.0035 |
Plasmodium vivax | glutathione reductase, putative | 0.0088 | 0.0462 | 0.3301 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0032 | 0.0065 | 0.0417 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0089 | 0.0466 | 0.0466 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0059 | 0.026 | 0.1857 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0059 | 0.026 | 0.0375 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0221 | 0.1401 | 0.202 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0059 | 0.026 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0112 | 0.0633 | 0.0633 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.008 | 0.0405 | 0.2854 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0106 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1401 | 0.2306 |
Onchocerca volvulus | 0.032 | 0.2097 | 0.3017 | |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0282 | 0.1828 | 0.1828 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.008 | 0.0405 | 0.2854 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0032 | 0.0065 | 0.0467 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0017 | 0.0123 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.003 | 0.0056 | 0.2137 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0031 | 0.0057 | 0.0094 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0032 | 0.0065 | 0.0059 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0023 | 0.0007 | 0.0012 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.008 | 0.0405 | 0.2854 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0032 | 0.0065 | 0.0413 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0023 | 0.0007 | 0.0011 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0319 | 0.209 | 1 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0031 | 0.0057 | 0.0356 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0199 | 0.1244 | 0.5953 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0023 | 0.0007 | 0.0007 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0282 | 0.1828 | 0.301 |
Trichomonas vaginalis | set domain proteins, putative | 0.1007 | 0.6935 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0038 | 0.0106 | 0.0508 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0031 | 0.0057 | 0.0057 |
Echinococcus multilocularis | snurportin 1 | 0.0625 | 0.4243 | 0.4243 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0056 | 0.008 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0031 | 0.0057 | 0.0407 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0841 | 0.5768 | 0.5768 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0059 | 0.0254 | 0.0254 |
Brugia malayi | cytochrome P450 | 0.0032 | 0.0065 | 0.0108 |
Echinococcus granulosus | snurportin 1 | 0.0625 | 0.4243 | 0.4243 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0199 | 0.1244 | 0.8881 |
Mycobacterium ulcerans | lipase LipD | 0.0221 | 0.1401 | 1 |
Onchocerca volvulus | 0.0221 | 0.1401 | 0.2011 | |
Onchocerca volvulus | 0.0028 | 0.004 | 0.0047 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0221 | 0.1401 | 0.1401 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.008 | 0.0405 | 0.2825 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0282 | 0.1828 | 0.1828 |
Schistosoma mansoni | tar DNA-binding protein | 0.041 | 0.2731 | 0.2731 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0023 | 0.0007 | 0.0035 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.008 | 0.0405 | 0.0406 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0112 | 0.0633 | 0.0912 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0059 | 0.026 | 0.0428 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0625 | 0.4243 | 0.6985 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0405 | 0.0667 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.011 | 0.0619 | 0.0619 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0089 | 0.0466 | 0.0466 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0017 | 0.0123 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0319 | 0.209 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0031 | 0.0057 | 0.0057 |
Toxoplasma gondii | ABC1 family protein | 0.0221 | 0.1401 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0059 | 0.0254 | 0.1217 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0045 | 0.0158 | 0.0757 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0032 | 0.0065 | 0.0417 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0023 | 0.0007 | 0.0035 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0032 | 0.0065 | 0.0059 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0032 | 0.0065 | 0.0059 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0179 | 0.1104 | 0.1104 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1401 | 0.2306 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0221 | 0.1401 | 0.6703 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0023 | 0.0007 | 0.0007 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0052 | 0.0211 | 0.0211 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0017 | 0.0082 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0069 | 0.0329 | 0.0329 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0032 | 0.0065 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Brugia malayi | PHD-finger family protein | 0.0076 | 0.038 | 0.0626 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0106 | 0.0153 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0032 | 0.0065 | 0.0417 |
Entamoeba histolytica | hypothetical protein | 0.0047 | 0.0176 | 0.2771 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.008 | 0.0405 | 0.0406 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0045 | 0.0158 | 0.0757 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0106 | 0.167 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0133 | 0.0781 | 0.0781 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0179 | 0.1104 | 0.1104 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0106 | 0.0153 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0032 | 0.0065 | 0.0417 |
Brugia malayi | beta-lactamase family protein | 0.0221 | 0.1401 | 0.2306 |
Leishmania major | trypanothione reductase | 0.0088 | 0.0462 | 0.2212 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0031 | 0.0057 | 0.0356 |
Leishmania major | hypothetical protein, conserved | 0.0221 | 0.1401 | 0.6703 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0032 | 0.0065 | 0.0059 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0032 | 0.0065 | 0.0417 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0112 | 0.0633 | 1 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0031 | 0.0057 | 0.0057 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0221 | 0.1401 | 0.1401 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0038 | 0.0106 | 0.0153 |
Trichomonas vaginalis | importin beta-1, putative | 0.0047 | 0.0176 | 0.0254 |
Plasmodium falciparum | acyl-CoA synthetase | 0.006 | 0.0263 | 0.5682 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0221 | 0.1401 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0221 | 0.1401 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0199 | 0.1244 | 0.1244 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0032 | 0.0065 | 0.0059 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0023 | 0.0007 | 0.0159 |
Trypanosoma cruzi | ISWI complex protein | 0.0047 | 0.0173 | 0.0826 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0059 | 0.0254 | 0.1815 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0032 | 0.0065 | 0.0417 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0317 | 0.1516 |
Plasmodium falciparum | thioredoxin reductase | 0.0031 | 0.0057 | 0.1233 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0031 | 0.0057 | 0.0273 |
Trypanosoma brucei | ISWI complex protein | 0.0047 | 0.0173 | 0.0826 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0052 | 0.0211 | 0.0211 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0007 | 0.0012 |
Schistosoma mansoni | zinc finger protein | 0.0047 | 0.0173 | 0.0173 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0031 | 0.0057 | 0.0068 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0133 | 0.0781 | 0.1285 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0405 | 0.0667 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0112 | 0.0633 | 0.0633 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0032 | 0.0065 | 0.0059 |
Brugia malayi | RNA recognition motif domain containing protein | 0.041 | 0.2731 | 0.4497 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.1033 | 0.1033 |
Echinococcus granulosus | importin subunit beta 1 | 0.0059 | 0.0254 | 0.0254 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.003 | 0.0056 | 0.008 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0031 | 0.0057 | 0.2191 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0053 | 0.0215 | 0.103 |
Echinococcus multilocularis | GPCR, family 2 | 0.0133 | 0.0781 | 0.0781 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0032 | 0.0065 | 0.0417 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0199 | 0.1244 | 0.8875 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.0781 | 0.0781 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0031 | 0.0057 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.2097 | 0.3453 |
Brugia malayi | Cytochrome P450 family protein | 0.0032 | 0.0065 | 0.0108 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0062 | 0.0276 | 0.1319 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.011 | 0.0619 | 0.0619 |
Brugia malayi | MH2 domain containing protein | 0.0261 | 0.1678 | 0.2763 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0031 | 0.0057 | 0.0273 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0199 | 0.1244 | 0.8875 |
Echinococcus granulosus | geminin | 0.0913 | 0.6275 | 0.6275 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0052 | 0.0211 | 0.0211 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.008 | 0.0405 | 0.2825 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0031 | 0.0057 | 0.0407 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0204 | 0.0203 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0032 | 0.0065 | 0.0417 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.006 | 0.0263 | 0.0261 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.006 | 0.0263 | 1 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0023 | 0.0007 | 0.0012 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0282 | 0.1828 | 0.1828 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0421 | 0.2808 | 0.4623 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0133 | 0.0781 | 0.0781 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0051 | 0.0204 | 0.1409 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0317 | 0.1516 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0032 | 0.0065 | 0.0313 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.003 | 0.0056 | 0.008 |
Echinococcus granulosus | GPCR family 2 | 0.0133 | 0.0781 | 0.0781 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0221 | 0.1401 | 0.1423 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.137 | 0.2256 |
Echinococcus multilocularis | zinc finger protein | 0.006 | 0.0265 | 0.0265 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0221 | 0.1401 | 0.202 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 48 % | DNDI: Inhibition of Human African Trypanosomiasis, SBRI 427, in vitro at 2 ug.mL-1 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.