Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1527 | 0.2976 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.1527 | 0.3346 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.824 | 0.824 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4565 | 0.8893 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.1527 | 0.1527 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.1527 | 0.1527 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4565 | 0.8893 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.1527 | 0.3346 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.4565 | 0.4565 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.1527 | 0.3346 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 1 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.5133 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.824 | 0.824 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.4565 | 0.4565 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.4565 | 0.4565 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1527 | 0.2976 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.4565 | 0.4565 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.4565 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4565 | 0.8893 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 1 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.1527 | 0.3346 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.824 | 0.824 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4565 | 0.8893 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.824 | 0.824 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.1527 | 0.3346 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1527 | 0.2976 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0 | 0.5 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.1527 | 0.1527 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.4565 | 0.8893 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.1527 | 0.1527 |
Brugia malayi | RNA binding protein | 0.0062 | 0.4565 | 0.4565 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.5133 | 0.5133 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.4565 | 0.4565 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.1527 | 0.3346 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.1527 | 0.2976 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.5133 | 0.5133 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.4565 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.