Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0637 | 0.0916 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0245 | 0.87 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.3321 | 0.4779 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0637 | 0.0916 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.538 | 0.6184 |
Trichomonas vaginalis | set domain proteins, putative | 0.0279 | 1 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.3321 | 0.4779 |
Echinococcus granulosus | geminin | 0.02 | 0.6951 | 1 |
Schistosoma mansoni | hypothetical protein | 0.02 | 0.6951 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0105 | 0.3321 | 0.4779 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0105 | 0.3321 | 0.4779 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0159 | 0.538 | 0.5066 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0637 | 0.0916 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0637 | 0.5 |
Onchocerca volvulus | Huntingtin homolog | 0.0146 | 0.4894 | 0.4547 |
Brugia malayi | ecdysteroid receptor | 0.0159 | 0.538 | 0.6184 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.0587 | 0.0845 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.4894 | 0.5626 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0637 | 0.0916 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0637 | 0.0916 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0105 | 0.3321 | 0.4779 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0828 | 0.0952 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.1541 | 0.1772 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0637 | 0.0732 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.4894 | 0.5626 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0637 | 0.0916 |
Brugia malayi | hypothetical protein | 0.0146 | 0.4894 | 0.5626 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0105 | 0.3321 | 0.4779 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0059 | 0.1541 | 0.1772 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0637 | 0.0732 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0105 | 0.3321 | 0.3818 |
Schistosoma mansoni | hypothetical protein | 0.02 | 0.6951 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0059 | 0.1541 | 0.1772 |
Onchocerca volvulus | Huntingtin homolog | 0.0146 | 0.4894 | 0.4547 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0828 | 0.1191 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.3321 | 0.4779 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0637 | 0.0916 |
Echinococcus multilocularis | geminin | 0.02 | 0.6951 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0105 | 0.3321 | 0.3818 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0637 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0828 | 0.0952 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0059 | 0.1541 | 0.1772 |
Brugia malayi | Pre-SET motif family protein | 0.0245 | 0.87 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.