Detailed information for compound 1047538

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 218.336 | Formula: C10H20NO2S+
  • H donors: 0 H acceptors: 1 LogP: 1.15 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][S+]1C[C@@H](O[C@@H]1C)[C@@H]1CCC[N+]1(C)C
  • InChi: 1S/C10H20NO2S/c1-8-13-10(7-14(8)12)9-5-4-6-11(9,2)3/h8-10H,4-7H2,1-3H3/q+1/t8-,9-,10+,14?/m0/s1
  • InChiKey: DAXFFIHSDRDSKA-UDAJDXAQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans beta-lactamase 0.0037 0.0062 0.0415
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.012 0.0348 0.0348
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0225 0.0707 0.0707
Echinococcus granulosus lysosomal acid lipase:cholesteryl ester 0.0058 0.0135 0.0346
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.0114 0.0295
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0255 0.0842
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.0729 0.1875
Leishmania major DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0112 0.0319 0.0406
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Toxoplasma gondii ABC1 family protein 0.0037 0.0062 0.1939
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0062 0.0079
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0009 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1023 1
Brugia malayi alpha/beta hydrolase 0.0034 0.0054 0.0178
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0061 0.0667
Echinococcus granulosus regulator of G protein signaling 7 0.003 0.0041 0.0104
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus granulosus glycine receptor subunit alpha 1 0.0242 0.0764 0.1966
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0009 0.003
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0114 0.0378
Treponema pallidum cyclic nucleotide binding protein 0.0019 0.0003 0.0031
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0242 0.0764 0.0975
Onchocerca volvulus 0.0093 0.0255 0.3314
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus multilocularis neuropeptides capa receptor 0.0225 0.0707 0.0902
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0225 0.0707 0.2337
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0225 0.0707 0.0902
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0061 0.0762
Schistosoma mansoni cpg binding protein 0.0062 0.015 0.0497
Schistosoma mansoni lipoxygenase 0.0258 0.0819 0.2708
Mycobacterium ulcerans exported protease 0.0034 0.0054 0.0362
Mycobacterium tuberculosis Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) 0.0034 0.0054 0.0392
Trypanosoma cruzi cAMP response protein 1 0.0019 0.0003 0.0035
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0019 0.0003 0.0035
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Trypanosoma brucei unspecified product 0.0021 0.0009 0.0098
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0019 0.0003 0.0031
Mycobacterium tuberculosis Possible haloalkane dehalogenase 0.0034 0.0054 0.0392
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.0729 0.093
Schistosoma mansoni amine GPCR 0.0225 0.0707 0.2337
Loa Loa (eye worm) hypothetical protein 0.013 0.0383 0.0383
Onchocerca volvulus 0.0052 0.0114 0.1463
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0003 0.0031
Brugia malayi ab-hydrolase associated lipase region family protein 0.0058 0.0135 0.0445
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0046 0.0093 0.101
Echinococcus granulosus neuropeptide receptor 0.0225 0.0707 0.1819
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0112 0.0319 0.0319
Treponema pallidum catabolite gene activator (Crp) 0.0019 0.0003 0.0031
Brugia malayi hypothetical protein 0.0112 0.0319 0.1053
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Echinococcus multilocularis fmrfamide receptor 0.0225 0.0707 0.0902
Echinococcus multilocularis muscleblind protein 1 0.0302 0.0969 0.1236
Schistosoma mansoni acetylcholine receptor subunit beta 0.0112 0.0319 0.1053
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0027 0.0029 0.0037
Echinococcus granulosus axis inhibition protein axin 0.0021 0.001 0.0025
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0242 0.0764 0.1966
Brugia malayi AKH receptor 0.0225 0.0707 0.2337
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0188 0.0484
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0054 0.3639
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0062 0.0415
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0255 0.0842
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.0009
Echinococcus multilocularis expressed protein 0.0414 0.1349 0.1721
Onchocerca volvulus 0.0153 0.0459 0.5993
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0225 0.0707 0.2337
Echinococcus granulosus rhodopsin orphan GPCR 0.0225 0.0707 0.1819
Echinococcus granulosus g-protein coupled receptor 0.0225 0.0707 0.1819
Echinococcus multilocularis somatostatin receptor 0.0225 0.0707 0.0902
Loa Loa (eye worm) hypothetical protein 0.0101 0.0282 0.0282
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.004 0.0075 0.0818
Echinococcus multilocularis rhodopsin orphan GPCR 0.0225 0.0707 0.0902
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Brugia malayi beta-lactamase 0.0037 0.0062 0.0205
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.035 0.2546
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0147 0.0438 0.0438
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0062 0.4181
Mycobacterium ulcerans proline iminopeptidase PIP 0.0034 0.0054 0.0362
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0155 0.0468 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0287 0.0917 1
Echinococcus multilocularis geminin 0.0187 0.0575 0.0733
Brugia malayi hydrolase, alpha/beta fold family protein 0.0034 0.0054 0.0178
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0144 0.0969
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0061 0.0762
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0225 0.0707 0.1819
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0009 0.0023
Schistosoma mansoni loxhd1 0.0062 0.0148 0.049
Mycobacterium ulcerans homoserine O-acetyltransferase 0.0034 0.0054 0.0362
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0027 0.0029 0.0075
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0242 0.0764 0.1966
Echinococcus granulosus hyperpolarization activated cyclic 0.0027 0.0029 0.0075
Echinococcus multilocularis neuropeptide receptor 0.0225 0.0707 0.0902
Schistosoma mansoni amine GPCR 0.0225 0.0707 0.2337
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0019 0.0003 0.0035
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.001 0.0032
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0225 0.0707 0.2337
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0046 0.0093 0.0306
Echinococcus multilocularis voltage gated potassium channel 0.0038 0.0066 0.0084
Echinococcus multilocularis glycine receptor subunit beta 0.0242 0.0764 0.0975
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0225 0.0707 0.0707
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0242 0.0764 0.1966
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Brugia malayi MH2 domain containing protein 0.0239 0.0753 0.2489
Loa Loa (eye worm) hypothetical protein 0.013 0.0383 0.0383
Trypanosoma brucei DNA polymerase beta thumb, putative 0.004 0.0075 0.0818
Echinococcus granulosus neuropeptide receptor 0.0225 0.0707 0.1819
Loa Loa (eye worm) MH2 domain-containing protein 0.0239 0.0753 0.0753
Echinococcus granulosus biogenic amine 5HT receptor 0.0225 0.0707 0.1819
Schistosoma mansoni hypothetical protein 0.0225 0.0707 0.2337
Echinococcus multilocularis g-protein coupled receptor 0.0225 0.0707 0.0902
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.013 0.0383 0.1264
Echinococcus multilocularis tumor protein p63 0.0636 0.2111 0.2693
Loa Loa (eye worm) RGS-3 protein 0.0021 0.001 0.001
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0318 0.1023 1
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus granulosus cpg binding protein 0.0062 0.015 0.0387
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0061 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0225 0.0707 0.1819
Loa Loa (eye worm) hypothetical protein 0.0153 0.0459 0.0459
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0019 0.0003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0905 0.3026 0.3026
Echinococcus granulosus RUN 0.0062 0.0148 0.0381
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0009 0.0087
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0029 0.0097
Schistosoma mansoni regulator of G protein signaling 0.0021 0.001 0.0032
Echinococcus granulosus cGMP dependent protein kinase 1 0.0019 0.0003 0.0008
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.001 0.0012
Schistosoma mansoni hypothetical protein 0.0046 0.0096 0.0316
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0009 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0003 0.0023
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0242 0.0764 0.0975
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0144 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0003 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0319 0.1053
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0019 0.0003 0.0011
Chlamydia trachomatis pyruvate kinase 0.0036 0.0061 1
Echinococcus granulosus voltage gated potassium channel 0.0038 0.0066 0.0169
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0225 0.0707 0.1819
Loa Loa (eye worm) hypothetical protein 0.0058 0.0135 0.0135
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.01 0.0257
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Schistosoma mansoni nAChR subunit 0.0112 0.0319 0.1053
Onchocerca volvulus 0.0225 0.0707 0.9252
Schistosoma mansoni hypothetical protein 0.0841 0.2811 0.9288
Mycobacterium tuberculosis Probable carboxylesterase CaeA 0.0034 0.0054 0.0392
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0187 0.2039
Echinococcus multilocularis cpg binding protein 0.0062 0.015 0.0192
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0038 0.0069 0.0499
Echinococcus multilocularis acetylcholinesterase 0.0905 0.3026 0.3861
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0009 0.0087
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0136 0.0401 0.4372
Leishmania major pyruvate kinase 0.0036 0.0061 0.0667
Loa Loa (eye worm) hypothetical protein 0.0153 0.0459 0.0459
Leishmania major hypothetical protein, conserved 0.0019 0.0003 0.0035
Mycobacterium ulcerans haloalkane dehalogenase 0.0034 0.0054 0.0362
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.013 0.0383 0.0383
Loa Loa (eye worm) hypothetical protein 0.0153 0.0459 0.0459
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0059 0.0139 0.0177
Echinococcus granulosus pyruvate kinase 0.0036 0.0061 0.0157
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0242 0.0764 0.2525
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.01 0.0128
Echinococcus granulosus BC026374 protein S09 family 0.0153 0.0459 0.1181
Loa Loa (eye worm) hypothetical protein 0.0037 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Onchocerca volvulus Huntingtin homolog 0.013 0.038 0.4957
Echinococcus granulosus rhodopsin orphan GPCR 0.0225 0.0707 0.1819
Echinococcus multilocularis pyruvate kinase 0.0019 0.0001 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0054 0.3639
Toxoplasma gondii isocitrate dehydrogenase 0.0046 0.0093 0.29
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0019 0.0003 0.0004
Mycobacterium ulcerans 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD 0.0455 0.1491 1
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0027 0.0029 0.0075
Schistosoma mansoni rab6-interacting 0.0062 0.0148 0.049
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Schistosoma mansoni lipoxygenase 0.037 0.1199 0.3962
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0225 0.0707 0.2337
Loa Loa (eye worm) ACC-1 protein 0.0242 0.0764 0.0764
Loa Loa (eye worm) AGC/PKG protein kinase 0.0019 0.0003 0.0003
Echinococcus granulosus allatostatin A receptor 0.0225 0.0707 0.1819
Loa Loa (eye worm) hypothetical protein 0.0153 0.0459 0.0459
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0153 0.0459 0.1181
Echinococcus multilocularis g protein coupled receptor 0.0225 0.0707 0.0902
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0225 0.0707 0.2337
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0242 0.0764 0.2525
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Mycobacterium leprae POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE) 0.0034 0.0054 0.1092
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0019 0.0003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0308 0.2244
Onchocerca volvulus 0.0225 0.0707 0.9252
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.001 0.0032
Schistosoma mansoni neuropeptide receptor 0.0225 0.0707 0.2337
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.001 0.0025
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0046 0.0096 0.0316
Mycobacterium ulcerans hypothetical protein 0.0034 0.0054 0.0362
Echinococcus granulosus geminin 0.0187 0.0575 0.1478
Loa Loa (eye worm) hypothetical protein 0.0046 0.0096 0.0096
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0019 0.0003 0.0099
Mycobacterium leprae POSSIBLE SECRETED PROTEASE 0.0034 0.0054 0.1092
Schistosoma mansoni biogenic amine receptor 0.0225 0.0707 0.2337
Onchocerca volvulus 0.0225 0.0707 0.9252
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.01 0.0727
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.001 0.0012
Brugia malayi putative neuropeptide receptor NPR1 0.0225 0.0707 0.2337
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0308 0.2244
Echinococcus granulosus fmrfamide receptor 0.0225 0.0707 0.1819
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0009 0.0098
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0046 0.0093 0.101
Loa Loa (eye worm) hypothetical protein 0.0093 0.0255 0.0255
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0034 0.0054 0.0527
Loa Loa (eye worm) hypothetical protein 0.0153 0.0459 0.0459
Brugia malayi hypothetical protein 0.0153 0.0459 0.1517
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.001 0.0032
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0147 0.0438 0.1446
Brugia malayi ORL1-like opioid receptor 0.0225 0.0707 0.2337
Echinococcus granulosus 7TM GPCR rhodopsin 0.0225 0.0707 0.1819
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0062 0.0062
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0019 0.0003 0.0004
Brugia malayi putative neuropeptide receptor 0.0225 0.0707 0.2337
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.0114 0.1463
Mycobacterium ulcerans hypothetical protein 0.0151 0.0453 0.304
Plasmodium falciparum LCCL domain-containing protein 0.0062 0.0148 1
Leishmania major hypothetical protein, conserved 0.0034 0.0054 0.0588
Brugia malayi Thioredoxin reductase 0.0048 0.01 0.033
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0242 0.0764 0.1966
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Schistosoma mansoni hypothetical protein 0.0046 0.0096 0.0316
Echinococcus granulosus sex peptide receptor 0.0225 0.0707 0.1819
Entamoeba histolytica hypothetical protein 0.0146 0.0436 0.4256
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0003 0.0011
Echinococcus multilocularis G protein coupled receptor 139 0.0225 0.0707 0.0902
Mycobacterium ulcerans hypothetical protein 0.0019 0.0003 0.0021
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.037 0.1199 0.153
Loa Loa (eye worm) ab-hydrolase associated lipase region family protein 0.0092 0.0251 0.0251
Loa Loa (eye worm) hypothetical protein 0.013 0.0383 0.0383
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0308 0.2244
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Leishmania major hypothetical protein, unknown function 0.0019 0.0003 0.0035
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0187 0.0618
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0019 0.0003 0.0214
Mycobacterium tuberculosis 4,9-DHSA hydrolase 0.0421 0.1374 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0225 0.0707 0.0902
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.0114 0.0114
Echinococcus granulosus g protein coupled receptor 0.0225 0.0707 0.1819
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0034 0.0054 0.0527
Echinococcus granulosus histone acetyltransferase MYST2 0.0059 0.0139 0.0358
Echinococcus multilocularis neuroligin 0.0153 0.0459 0.0586
Loa Loa (eye worm) hypothetical protein 0.0302 0.0969 0.0969
Plasmodium vivax glutathione reductase, putative 0.0048 0.01 0.6746
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0225 0.0707 0.0902
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0061 0.0061
Mycobacterium tuberculosis Probable oxidoreductase 0.0034 0.0054 0.0392
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0058 0.0135 0.0135
Schistosoma mansoni tar DNA-binding protein 0.0127 0.037 0.1223
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0225 0.0707 0.0902
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0144 0.4522
Brugia malayi excitatory GABA receptor EXP-1A 0.0242 0.0764 0.2525
Brugia malayi N-terminal motif family protein 0.0199 0.0615 0.2033
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.001 0.001
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.014 0.014
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.001 0.0095
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0905 0.3026 1
Schistosoma mansoni hypothetical protein 0.0225 0.0707 0.2337
Schistosoma mansoni survival motor neuron protein 0.0047 0.0099 0.0326
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0027 0.0029 0.0029
Onchocerca volvulus 0.0148 0.0443 0.5781
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0436 0.0556
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0436 0.1121
Echinococcus granulosus dnaJ subfamily B 0.0841 0.2811 0.723
Echinococcus multilocularis orexin receptor type 2 0.0225 0.0707 0.0902
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.035 0.7461
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Echinococcus multilocularis nAChR subunit 0.013 0.0383 0.0488
Onchocerca volvulus Putative nachr subunit 0.0242 0.0764 1
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0061 0.0762
Echinococcus granulosus lysosomal acid lipase:cholesteryl ester 0.0092 0.0251 0.0646
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0144 0.1575
Leishmania major hypothetical protein, conserved 0.0037 0.0062 0.0676
Schistosoma mansoni polycystin 1-related 0.0062 0.0148 0.049
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.001 0.0025
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0019 0.0003 0.0008
Entamoeba histolytica hypothetical protein 0.0021 0.001 0.0095
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0082 0.0104
Brugia malayi Calcitonin receptor-like protein seb-1 0.0147 0.0438 0.1446
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0225 0.0707 0.2337
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0318 0.1023 1
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0019 0.0003 0.0099
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.013 0.0383 0.1264
Echinococcus granulosus dna polymerase kappa 0.0021 0.0009 0.0023
Schistosoma mansoni neurotransmitter gated ion channel 0.0112 0.0319 0.1053
Echinococcus multilocularis pyruvate kinase 0.0036 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Loa Loa (eye worm) TYRA-2 protein 0.0225 0.0707 0.0707
Mycobacterium ulcerans epoxide hydrolase EphE 0.0034 0.0054 0.0362
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0046 0.0096 0.0122
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Trichomonas vaginalis hydrolase, putative 0.0034 0.0054 0.0527
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Brugia malayi RNA binding protein 0.0127 0.037 0.1223
Brugia malayi Cation transporter family protein 0.0242 0.0764 0.2525
Schistosoma mansoni DNA polymerase eta 0.0021 0.0009 0.003
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0148 0.0381
Mycobacterium ulcerans hypothetical protein 0.0037 0.0062 0.0415
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0225 0.0707 0.2337
Mycobacterium ulcerans hypothetical protein 0.0034 0.0054 0.0362
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0113 0.0322 0.3145
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0046 0.0093 0.101
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0027 0.0029 0.0097
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.01 0.109
Entamoeba histolytica alpha/beta hydrolase domain protein, putative 0.0034 0.0054 0.0527
Echinococcus granulosus para nitrobenzyl esterase 0.0153 0.0459 0.1181
Onchocerca volvulus 0.0242 0.0764 1
Echinococcus multilocularis carboxylesterase 5A 0.0905 0.3026 0.3861
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0225 0.0707 0.2337
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0061 0.0598
Schistosoma mansoni neuroligin 3 (S09 family) 0.0153 0.0459 0.1517
Echinococcus granulosus lipoxygenase domain containing protein 0.0062 0.0148 0.0381
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0062 0.0605
Loa Loa (eye worm) hypothetical protein 0.013 0.0383 0.0383
Schistosoma mansoni hypothetical protein 0.0187 0.0575 0.1899
Leishmania major hydrolase-like protein 0.0034 0.0054 0.0588
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.001 0.0032
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0242 0.0764 0.1966
Brugia malayi hypothetical protein 0.0232 0.0729 0.2408
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0009 0.003
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0225 0.0707 0.9252
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1023 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0154 0.1682
Toxoplasma gondii thioredoxin reductase 0.0048 0.01 0.3129
Loa Loa (eye worm) hypothetical protein 0.0027 0.0029 0.0029
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Echinococcus multilocularis rhodopsin orphan GPCR 0.0225 0.0707 0.0902
Onchocerca volvulus 0.0047 0.0099 0.1255
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0188 0.0188
Onchocerca volvulus 0.0037 0.0062 0.0772
Echinococcus granulosus neuropeptides capa receptor 0.0225 0.0707 0.1819
Onchocerca volvulus 0.0225 0.0707 0.9252
Loa Loa (eye worm) hypothetical protein 0.0063 0.0152 0.0152
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0061 0.0667
Schistosoma mansoni opsin-like receptor 0.0225 0.0707 0.2337
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0062 0.0159
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.001 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.001 0.0032
Schistosoma mansoni lipase 1 0.0058 0.0135 0.0445
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0319 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0225 0.0707 0.1819
Leishmania major hypothetical protein, conserved 0.0034 0.0054 0.0588
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0153 0.0459 0.3341
Echinococcus granulosus neuropeptide FF receptor 2 0.0225 0.0707 0.1819
Schistosoma mansoni hypothetical protein 0.0047 0.0099 0.0326
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0242 0.0764 0.2525
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0255 0.0325
Echinococcus granulosus glycine receptor subunit beta 0.0242 0.0764 0.1966
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Schistosoma mansoni alpha-1 adrenergic receptor 0.0225 0.0707 0.2337
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0112 0.0319 0.0406
Schistosoma mansoni neuropeptide F-like receptor 0.0225 0.0707 0.2337
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0034 0.0054 0.0588
Plasmodium vivax alpha/beta hydrolase, putative 0.0034 0.0054 0.3639
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0019 0.0003 0.0214
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0153 0.0459 0.1517
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0225 0.0707 0.1819
Loa Loa (eye worm) hypothetical protein 0.013 0.038 0.038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0242 0.0764 0.2525
Onchocerca volvulus 0.0225 0.0707 0.9252
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0046 0.0096 0.0122
Echinococcus granulosus acetylcholinesterase 0.0905 0.3026 0.7785
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0112 0.0319 0.1053
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0037 0.0062 0.0062
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0046 0.0093 0.0238
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0066
Trypanosoma cruzi hydrolase-like protein, putative 0.0034 0.0054 0.0588
Loa Loa (eye worm) doublecortin family protein 0.0062 0.0148 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0095
Echinococcus granulosus G protein coupled receptor 139 0.0225 0.0707 0.1819
Brugia malayi G protein-coupled receptor 0.0225 0.0707 0.2337
Echinococcus granulosus tm gpcr rhodopsin 0.0225 0.0707 0.1819
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0154 0.1034
Schistosoma mansoni growth hormone secretagogue receptor 0.0225 0.0707 0.2337
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.001 0.001
Schistosoma mansoni biogenic amine (5HT) receptor 0.0225 0.0707 0.2337
Onchocerca volvulus 0.0225 0.0707 0.9252
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Brugia malayi hypothetical protein 0.0112 0.0319 0.1053
Schistosoma mansoni hypothetical protein 0.0046 0.0096 0.0316
Plasmodium falciparum thioredoxin reductase 0.0048 0.01 0.6746
Echinococcus multilocularis allatostatin A receptor 0.0225 0.0707 0.0902
Brugia malayi RNA recognition motif domain containing protein 0.0127 0.037 0.1223
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0029 0.0097
Echinococcus multilocularis abhydrolase domain containing protein 16A 0.0034 0.0054 0.0069
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0242 0.0764 0.2525
Brugia malayi Fli-1 protein 0.0223 0.0699 0.2309
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0225 0.0707 0.0707
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0059 0.0139 0.0459
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Schistosoma mansoni tar DNA-binding protein 0.0127 0.037 0.1223
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.0034 0.0054 0.0667
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0062 0.0676
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0225 0.0707 0.2337
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0019 0.0003 0.0011
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2314 0.7839 1
Schistosoma mansoni tar DNA-binding protein 0.0127 0.037 0.1223
Trypanosoma cruzi cAMP binding protein, putative 0.0019 0.0003 0.0035
Schistosoma mansoni hypothetical protein 0.01 0.0279 0.0923
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0049 0.0105 0.1146
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0155 0.0468 0.3404
Loa Loa (eye worm) hydrolase 0.0034 0.0054 0.0054
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0225 0.0707 0.0902
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0095
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0242 0.0764 0.2525
Loa Loa (eye worm) hypothetical protein 0.0037 0.0062 0.0062
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Mycobacterium tuberculosis Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (homoserine transacetylase) (HTA) 0.0034 0.0054 0.0392
Mycobacterium ulcerans exported protease 0.0034 0.0054 0.0362
Onchocerca volvulus 0.0037 0.0062 0.0772
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0187 0.0481
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0 0.5
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0154 0.1122
Schistosoma mansoni neuropeptide F-like receptor 0.0225 0.0707 0.2337
Loa Loa (eye worm) hypothetical protein 0.2947 1 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0319 0.1053
Schistosoma mansoni adenoreceptor 0.0225 0.0707 0.2337
Onchocerca volvulus 0.0225 0.0707 0.9252
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Mycobacterium ulcerans haloalkane dehalogenase 0.0034 0.0054 0.0362
Schistosoma mansoni hypothetical protein 0.0046 0.0096 0.0316
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0009 0.0098
Schistosoma mansoni opsin-like receptor 0.0225 0.0707 0.2337
Loa Loa (eye worm) G-protein coupled receptor 0.0225 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.0114 0.0146
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0242 0.0764 0.0975
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0112 0.0319 0.1053
Schistosoma mansoni hypothetical protein 0.0062 0.0148 0.049
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Onchocerca volvulus 0.0153 0.0459 0.5993
Echinococcus granulosus arachidonate 5 lipoxygenase 0.037 0.1199 0.3085
Trypanosoma cruzi Flagellar Member 6 0.0019 0.0003 0.0035
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Loa Loa (eye worm) hypothetical protein 0.0582 0.1924 0.1924
Loa Loa (eye worm) hypothetical protein 0.0147 0.0438 0.0438
Entamoeba histolytica hypothetical protein 0.0146 0.0436 0.4256
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0242 0.0764 0.0975
Schistosoma mansoni cpg binding protein 0.0062 0.015 0.0497
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0242 0.0764 0.2525
Echinococcus multilocularis rhodopsin orphan GPCR 0.0225 0.0707 0.0902
Echinococcus granulosus neuroligin 0.0153 0.0459 0.1181
Echinococcus multilocularis regulator of G protein signaling 7 0.003 0.0041 0.0052
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0029 0.0286
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0242 0.0764 0.0764
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0139 0.0139
Brugia malayi Cation transporter family protein 0.0242 0.0764 0.2525
Schistosoma mansoni pyruvate kinase 0.0036 0.0061 0.0202
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0208 0.0648 0.1668
Schistosoma mansoni biogenic amine receptor 0.0225 0.0707 0.2337
Brugia malayi latrophilin 2 splice variant baaae 0.01 0.0279 0.0923
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0136 0.0401 0.4372
Brugia malayi RE15519p 0.0225 0.0707 0.2337
Schistosoma mansoni voltage-gated potassium channel 0.0131 0.0384 0.127
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0019 0.0003 0.0011
Mycobacterium ulcerans hypothetical protein 0.0034 0.0054 0.0362
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0225 0.0707 0.2337
Echinococcus granulosus neuropeptide Y receptor 0.0225 0.0707 0.1819
Schistosoma mansoni regulator of G protein signaling 0.0021 0.001 0.0032
Loa Loa (eye worm) carboxylesterase 0.0905 0.3026 0.3026
Trypanosoma brucei trypanothione reductase 0.0048 0.01 0.109
Brugia malayi Dopamine receptor protein 1 0.0225 0.0707 0.2337
Brugia malayi Melatonin receptor type 1A 0.0225 0.0707 0.2337
Mycobacterium tuberculosis Conserved protein 0.0037 0.0062 0.0451
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0242 0.0764 0.2525
Echinococcus multilocularis neuropeptide receptor A26 0.1157 0.3888 0.4959
Loa Loa (eye worm) hypothetical protein 0.0302 0.0969 0.0969
Loa Loa (eye worm) hypothetical protein 0.0232 0.0729 0.0729
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0019 0.0003 0.0023
Schistosoma mansoni hypothetical protein 0.0146 0.0436 0.1439
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0242 0.0764 0.2525
Leishmania major trypanothione reductase 0.0048 0.01 0.109
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Echinococcus granulosus abhydrolase domain containing protein 11 0.0034 0.0054 0.0139
Loa Loa (eye worm) hypothetical protein 0.0153 0.0459 0.0459
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0062 0.0676
Echinococcus granulosus carboxylesterase 5A 0.0905 0.3026 0.7785
Loa Loa (eye worm) hypothetical protein 0.0037 0.0062 0.0062
Brugia malayi G-protein coupled receptor 0.0225 0.0707 0.2337
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0242 0.0764 0.1966
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0054 0.3639
Brugia malayi Carboxylesterase family protein 0.0153 0.0459 0.1517
Echinococcus granulosus neuropeptides capa receptor 0.0225 0.0707 0.1819
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Entamoeba histolytica hypothetical protein 0.013 0.0383 0.3739
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.001 0.0032
Echinococcus granulosus pyruvate kinase 0.0019 0.0001 0.0002
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0148 0.0189
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0225 0.0707 0.0902
Echinococcus granulosus pyruvate kinase 0.0019 0.0001 0.0002
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0242 0.0764 0.2525
Onchocerca volvulus 0.0242 0.0764 1
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0019 0.0003 0.0008
Echinococcus multilocularis abhydrolase domain containing protein 3 0.0034 0.0054 0.0069
Trypanosoma brucei protein kinase A regulatory subunit 0.0019 0.0003 0.0035
Onchocerca volvulus Lipase homolog 0.0092 0.0251 0.3261
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0034 0.0054 0.0392
Loa Loa (eye worm) fli-1 protein 0.0223 0.0699 0.0699
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0046 0.0093 0.0118
Schistosoma mansoni myosin xvIII 0.0225 0.0707 0.2337
Schistosoma mansoni nAChR subunit 0.0242 0.0764 0.2525
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0092 0.0251 0.0321
Schistosoma mansoni neuropeptide receptor 0.0225 0.0707 0.2337
Brugia malayi isocitrate dehydrogenase 0.0046 0.0093 0.0306
Schistosoma mansoni nAChR subunit 0.0242 0.0764 0.2525
Echinococcus granulosus rhodopsin orphan GPCR 0.0225 0.0707 0.1819
Plasmodium falciparum pyruvate kinase 0.0036 0.0061 0.413
Mycobacterium leprae Probable exported protease 0.0034 0.0054 0.1092
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0009 0.0011
Echinococcus granulosus tachykinin peptides receptor 99D 0.0225 0.0707 0.1819
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0242 0.0764 0.2525
Mycobacterium tuberculosis Conserved protein 0.0037 0.0062 0.0451
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1023 1
Onchocerca volvulus 0.013 0.0383 0.4987
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0225 0.0707 0.1819
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0009 0.003
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus multilocularis neuropeptides capa receptor 0.0225 0.0707 0.0902
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0187 0.2039
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0001 0.0057
Leishmania major hypothetical protein, conserved 0.0019 0.0003 0.0035
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus multilocularis regulator of G protein signaling 7 0.003 0.0041 0.0052
Mycobacterium ulcerans peroxidase BpoB 0.0034 0.0054 0.0362
Trypanosoma brucei cAMP binding protein, putative 0.0019 0.0003 0.0035
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0003 0.0011
Mycobacterium tuberculosis Conserved protein 0.0019 0.0003 0.0023
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0054
Schistosoma mansoni regulator of G protein signaling 0.0021 0.001 0.0032
Mycobacterium tuberculosis Carboxylesterase LipT 0.0153 0.0459 0.3341
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0225 0.0707 0.0707
Schistosoma mansoni myelin transcription factor 1 myt1 0.0059 0.0139 0.0459
Schistosoma mansoni cpg binding protein 0.0059 0.0139 0.0459
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0308 0.657
Echinococcus multilocularis neuropeptide Y receptor 0.0225 0.0707 0.0902
Mycobacterium leprae Probable lipase LipE 0.0037 0.0062 0.1265
Schistosoma mansoni amine GPCR 0.0225 0.0707 0.2337
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0112 0.0319 0.1053
Brugia malayi Dopamine receptor protein 2 0.0225 0.0707 0.2337
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0127 0.037 0.037
Schistosoma mansoni gabp alpha 0.0073 0.0188 0.0622
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0061 0.1916
Mycobacterium tuberculosis Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) 0.0034 0.0054 0.0392
Schistosoma mansoni acetylcholine receptor-related 0.0112 0.0319 0.1053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0225 0.0707 0.2337
Mycobacterium ulcerans regulatory protein 0.0019 0.0003 0.0021
Brugia malayi Muscleblind-like protein 0.0302 0.0969 0.3202
Echinococcus granulosus hypothetical protein 0.0225 0.0707 0.1819
Echinococcus granulosus tm gpcr rhodopsin 0.0225 0.0707 0.1819
Brugia malayi Ets-domain containing protein 0.0073 0.0188 0.0622
Brugia malayi PXA domain containing protein 0.0021 0.001 0.0032
Brugia malayi Ets-domain containing protein 0.0073 0.0188 0.0622
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0019 0.0003 0.0011
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0019 0.0003 0.0099
Echinococcus granulosus biogenic amine 5HT receptor 0.0225 0.0707 0.1819
Brugia malayi regulator of G-protein signaling egl-10 0.003 0.0041 0.0134
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0225 0.0707 0.0902
Schistosoma mansoni axis inhibition protein axin 0.0021 0.001 0.0032
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0153 0.0459 0.0586
Loa Loa (eye worm) acetylcholinesterase 1 0.0905 0.3026 0.3026
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0242 0.0764 0.0975
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0187 0.0618
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0187 0.0239
Echinococcus granulosus peptide allatostatin:somatostatin 0.0225 0.0707 0.1819
Echinococcus multilocularis pyruvate kinase 0.0019 0.0001 0.0001
Brugia malayi PXA domain containing protein 0.0021 0.001 0.0032
Loa Loa (eye worm) glutathione reductase 0.0048 0.01 0.01
Schistosoma mansoni amine GPCR 0.0225 0.0707 0.2337
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0046 0.0093 0.0118
Echinococcus multilocularis isocitrate dehydrogenase 0.0046 0.0093 0.0118
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0225 0.0707 0.2337
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0255 0.0842
Giardia lamblia Pyruvate kinase 0.0019 0.0001 0.0008
Schistosoma mansoni ets-related 0.0223 0.0699 0.2309
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0061 0.041
Giardia lamblia Pyruvate kinase 0.0036 0.0061 0.0598
Schistosoma mansoni hypothetical protein 0.0225 0.0707 0.2337
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0154 0.051
Echinococcus granulosus alpha 1A adrenergic receptor 0.0225 0.0707 0.1819
Schistosoma mansoni gliotactin 0.0153 0.0459 0.1517
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0242 0.0764 0.0975
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0019 0.0003 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0024 0.0024
Echinococcus granulosus abhydrolase domain containing protein 3 0.0034 0.0054 0.0139
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.004 0.0075 0.0818
Onchocerca volvulus 0.0037 0.0062 0.0772
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Echinococcus multilocularis pyruvate kinase 0.0029 0.0035 0.0045
Echinococcus granulosus tm gpcr rhodopsin 0.0225 0.0707 0.1819
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.0114 0.0295
Schistosoma mansoni voltage-gated potassium channel 0.0131 0.0384 0.127
Onchocerca volvulus 0.0112 0.0319 0.4146
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0062 0.0451
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0187 0.2039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1023 1
Echinococcus multilocularis neuropeptide s receptor 0.1157 0.3888 0.4959
Brugia malayi hypothetical protein 0.0112 0.0319 0.1053
Loa Loa (eye worm) melatonin receptor type 1A 0.0225 0.0707 0.0707
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0021 0.0011 0.0035
Schistosoma mansoni biogenic amine receptor 0.0225 0.0707 0.2337
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0061 0.0202
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0225 0.0707 0.0902
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0019 0.0003 0.0004
Leishmania major mitochondrial DNA polymerase beta 0.0287 0.0917 1
Echinococcus multilocularis neuropeptide Y receptor 0.0225 0.0707 0.0902
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0019 0.0003 0.0023
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0154 0.1034
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0144 0.0184
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.012 0.0348 0.115
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0255 0.0656
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Echinococcus granulosus somatostatin receptor 0.0225 0.0707 0.1819
Onchocerca volvulus 0.0242 0.0764 1
Brugia malayi hypothetical protein 0.0062 0.0148 0.049
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0144 0.0372
Echinococcus granulosus cGMP dependent protein kinase 0.0019 0.0003 0.0008
Echinococcus granulosus potassium voltage gated channel subfamily H 0.012 0.0348 0.0895
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0034 0.0054 0.0588
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0225 0.0707 0.2337
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0061 0.0598
Brugia malayi Carboxylesterase family protein 0.0153 0.0459 0.1517
Brugia malayi Serotonin receptor 0.0225 0.0707 0.2337
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0602 0.1993 0.6585
Brugia malayi hypothetical protein 0.0112 0.0319 0.1053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0225 0.0707 0.0902
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0066 0.0217
Trichomonas vaginalis esterase, putative 0.0037 0.0062 0.0605
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0062 0.0605
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0003 0.0031
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Mycobacterium ulcerans epoxide hydrolase EphF 0.0034 0.0054 0.0362
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0024
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0155 0.0468 0.3137
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0061 0.0445
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Mycobacterium tuberculosis Possible peroxidase BpoB (non-haem peroxidase) 0.0034 0.0054 0.0392
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0034 0.0054 0.0527
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0242 0.0764 0.0975
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0242 0.0764 0.1966
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.001 0.0025
Leishmania major DNA polymerase eta, putative 0.0021 0.0009 0.0098
Loa Loa (eye worm) hypothetical protein 0.013 0.0383 0.0383
Entamoeba histolytica hypothetical protein 0.0021 0.001 0.0095
Schistosoma mansoni hydrolase 0.0034 0.0054 0.0178
Mycobacterium ulcerans lignin peroxidase LipJ 0.0034 0.0054 0.0362
Echinococcus multilocularis hyperpolarization activated cyclic 0.0027 0.0029 0.0037
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0029 0.0286
Echinococcus granulosus neuropeptide Y receptor 0.0225 0.0707 0.1819
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0061 0.413
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1023 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0027 0.0029 0.0037
Mycobacterium tuberculosis Conserved protein 0.0037 0.0062 0.0451
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0242 0.0764 0.2525
Schistosoma mansoni neuropeptide receptor 0.0225 0.0707 0.2337
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0062 0.0605
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1023 1
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0054 0.0588
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0019 0.0003 0.0099
Echinococcus multilocularis pyruvate kinase 0.0019 0.0001 0.0001
Plasmodium falciparum epoxide hydrolase 1 0.0034 0.0054 0.3639
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0199 0.0615 0.8042
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Entamoeba histolytica hypothetical protein 0.0021 0.001 0.0095
Brugia malayi neuropeptide F receptor 0.0225 0.0707 0.2337
Mycobacterium ulcerans acyl-CoA synthetase 0.0034 0.0054 0.0362
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.035 0.2546
Brugia malayi Carboxylesterase family protein 0.0905 0.3026 1
Brugia malayi Doublecortin family protein 0.0062 0.0148 0.049
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0003 0.0011
Loa Loa (eye worm) transcription factor SMAD2 0.0239 0.0753 0.0753
Mycobacterium tuberculosis Conserved hypothetical protein 0.0151 0.0453 0.3298
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus granulosus patatin phospholipase domain containing protein 0.0019 0.0003 0.0008
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0062 0.0451
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0061 0.0667
Loa Loa (eye worm) G-protein coupled receptor 0.0225 0.0707 0.0707
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0225 0.0707 0.2337
Onchocerca volvulus 0.0153 0.0459 0.5993
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0144 0.0477
Mycobacterium ulcerans hypothetical protein 0.0019 0.0003 0.0021
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Onchocerca volvulus 0.0112 0.0319 0.4146
Toxoplasma gondii hypothetical protein 0.0046 0.0095 0.2981
Loa Loa (eye worm) acetylcholine receptor protein 0.0112 0.0319 0.0319
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0255 0.0842
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.001 0.0025
Brugia malayi hypothetical protein 0.0146 0.0436 0.1439
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0199 0.0615 0.0615
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.001 0.0032
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0242 0.0764 0.0975
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0027 0.0029 0.0037
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0027 0.0029 0.0075
Schistosoma mansoni hypothetical protein 0.0225 0.0707 0.2337
Echinococcus granulosus cGMP dependent protein kinase 1 0.0019 0.0003 0.0008
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0287 0.0917 1
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0019 0.0003 0.0011
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0062 0.0451
Leishmania major hydrolase-like protein,esterase-like protein 0.0034 0.0054 0.0588
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0062 0.0205
Onchocerca volvulus 0.0153 0.0459 0.5993
Echinococcus multilocularis rhodopsin orphan GPCR 0.0225 0.0707 0.0902
Mycobacterium ulcerans epoxide hydrolase EphB 0.0034 0.0054 0.0362
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0009 0.006
Schistosoma mansoni amine GPCR 0.0225 0.0707 0.2337
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0046 0.0093 0.6252
Echinococcus granulosus pyruvate kinase 0.0036 0.0061 0.0157
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Loa Loa (eye worm) abhydrolase domain-containing protein 2 0.0034 0.0054 0.0054
Onchocerca volvulus 0.0225 0.0707 0.9252
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0225 0.0707 0.2337
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0136 0.0401 0.4372
Brugia malayi Dopamine receptor 0.0225 0.0707 0.2337
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0029 0.0097
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0009 0.0009
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0062 0.0415
Mycobacterium ulcerans epoxide hydrolase EphA 0.0034 0.0054 0.0362
Mycobacterium tuberculosis Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase) 0.0034 0.0054 0.0392
Schistosoma mansoni neuropeptide f receptor 76f 0.0225 0.0707 0.2337
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.01 0.6746
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0009 0.003
Brugia malayi hypothetical protein 0.013 0.038 0.1257
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0113 0.0322 0.3145
Mycobacterium tuberculosis Probable reductase 0.0109 0.0308 0.2244
Brugia malayi hypothetical protein 0.0148 0.0443 0.1464
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0009 0.0087
Loa Loa (eye worm) carboxylesterase 0.0153 0.0459 0.0459
Onchocerca volvulus 0.0225 0.0707 0.9252
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Echinococcus granulosus GPCR family 2 0.0046 0.0096 0.0246
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0225 0.0707 0.1819
Schistosoma mansoni neurotransmitter gated ion channel 0.0112 0.0319 0.1053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0225 0.0707 0.0902
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0059 0.0139 0.0358
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0027 0.0029 0.0097
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0187 0.2039
Loa Loa (eye worm) LGC-31 protein 0.0242 0.0764 0.0764
Mycobacterium ulcerans carboxylesterase, LipT 0.0153 0.0459 0.3079
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0001 0.0027
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0242 0.0764 0.0975
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0062 0.0451
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0046 0.0096 0.0246
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0027 0.0029 0.0037
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0024 0.0231
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0365 0.1207
Loa Loa (eye worm) GABA receptor subunit 0.013 0.0383 0.0383
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0225 0.0707 0.0707
Onchocerca volvulus 0.0062 0.0148 0.1906
Schistosoma mansoni voltage-gated potassium channel 0.0027 0.0029 0.0097
Toxoplasma gondii isocitrate dehydrogenase 0.0046 0.0093 0.29
Echinococcus multilocularis abhydrolase domain containing 3 0.0034 0.0054 0.0069
Echinococcus granulosus 7tm_1 domain containing protein 0.0225 0.0707 0.1819
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0069 0.046
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.001 0.0012
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0153 0.0459 0.4486
Brugia malayi neuropeptide F receptor 0.0225 0.0707 0.2337
Schistosoma mansoni axis inhibition protein axin 0.0021 0.001 0.0032
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Schistosoma mansoni hypothetical protein 0.0319 0.1028 0.3395
Schistosoma mansoni nAChR subunit 0.0242 0.0764 0.2525
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Mycobacterium ulcerans bromoperoxidase BpoC 0.0034 0.0054 0.0362
Treponema pallidum catabolite gene activator 0.0019 0.0003 0.0031
Loa Loa (eye worm) MBCTL1 0.0059 0.0139 0.0139
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0034 0.0054 0.0527
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.001 0.0012
Plasmodium falciparum glutathione reductase 0.0048 0.01 0.6746
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.001 0.0025
Brugia malayi GnHR receptor homolog 0.0225 0.0707 0.2337
Brugia malayi G-protein coupled receptor 0.0225 0.0707 0.2337
Brugia malayi sulfakinin receptor protein 0.0225 0.0707 0.2337
Leishmania major protein kinase A regulatory subunit, putative 0.0019 0.0003 0.0035
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus multilocularis pyruvate kinase 0.0036 0.0061 0.0078
Echinococcus multilocularis glycine receptor subunit beta 0.0242 0.0764 0.0975
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0062 0.0605
Schistosoma mansoni opsin-like receptor 0.0225 0.0707 0.2337
Mycobacterium leprae Probable exported protease 0.0034 0.0054 0.1092
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.001
Onchocerca volvulus Lipase homolog 0.0092 0.0251 0.3261
Loa Loa (eye worm) hypothetical protein 0.049 0.1611 0.1611
Onchocerca volvulus 0.0242 0.0764 1
Brugia malayi hypothetical protein 0.0021 0.001 0.0032
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0066 0.0217
Leishmania major hydrolase, alpha/beta fold family-like protein 0.0034 0.0054 0.0588
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0054 0.0588
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0242 0.0764 0.1966
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0046 0.0096 0.0246
Echinococcus granulosus rhodopsin orphan GPCR 0.0225 0.0707 0.1819
Brugia malayi Egg laying defective protein 4 0.0019 0.0003 0.0011
Giardia lamblia DINP protein human, muc B family 0.0021 0.0009 0.0087
Echinococcus multilocularis lipoxygenase domain containing protein 0.0062 0.0148 0.0189
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0148
Echinococcus multilocularis rhodopsin orphan GPCR 0.0225 0.0707 0.0902
Loa Loa (eye worm) carboxylesterase 0.0153 0.0459 0.0459
Brugia malayi G protein-coupled receptor F59B2.13 0.0225 0.0707 0.2337
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0242 0.0764 0.0975
Schistosoma mansoni neurotransmitter gated ion channel 0.013 0.0383 0.1264
Trypanosoma brucei cAMP response protein 1, putative 0.0019 0.0003 0.0035
Toxoplasma gondii alpha/beta hydrolase, putative 0.0034 0.0054 0.1688
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0208 0.0648 0.0827
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0148
Echinococcus granulosus nAChR subunit 0.013 0.0383 0.0984
Leishmania major hypothetical protein, conserved 0.0019 0.0003 0.0035
Leishmania major pyruvate kinase 0.0036 0.0061 0.0667
Echinococcus granulosus pyruvate kinase 0.0019 0.0001 0.0002
Brugia malayi Carboxylesterase family protein 0.0153 0.0459 0.1517
Giardia lamblia Fructose-bisphosphate aldolase 0.0318 0.1023 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0225 0.0707 0.2337
Echinococcus multilocularis nAChR subunit 0.0242 0.0764 0.0975
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0114 0.0378
Echinococcus multilocularis dna polymerase eta 0.0021 0.0009 0.0011
Echinococcus granulosus neuropeptide receptor A26 0.1157 0.3888 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0225 0.0707 0.0902
Loa Loa (eye worm) TAR-binding protein 0.0127 0.037 0.037
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0003 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Echinococcus granulosus regulator of G protein signaling 7 0.003 0.0041 0.0104
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus multilocularis Polycystic kidney disease protein 0.0062 0.0148 0.0189
Schistosoma mansoni z-protein (S1r protein) 0.003 0.0041 0.0134
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0009 0.0098
Schistosoma mansoni tar DNA-binding protein 0.0127 0.037 0.1223
Mycobacterium ulcerans hypothetical protein 0.0019 0.0003 0.0021
Mycobacterium tuberculosis Probable haloalkane dehalogenase 0.0034 0.0054 0.0392
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0046 0.0093 0.6252
Echinococcus granulosus muscleblind protein 0.0302 0.0969 0.2493
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0009 0.0065
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0308 0.2244
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0225 0.0707 0.2337
Brugia malayi TAR-binding protein 0.0127 0.037 0.1223
Echinococcus granulosus dro:myosuppressin receptor 0.0225 0.0707 0.1819
Mycobacterium ulcerans lipase/esterase 0.0034 0.0054 0.0362
Leishmania major hydrolase-like protein,esterase-like protein 0.0034 0.0054 0.0588
Schistosoma mansoni lipase 1 0.0058 0.0135 0.0445
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0225 0.0707 0.9252
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.013 0.0383 0.1264
Entamoeba histolytica alpha/beta hydrolase fold protein, putative 0.0034 0.0054 0.0527
Loa Loa (eye worm) hypothetical protein 0.013 0.0383 0.0383
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0287 0.0917 1
Schistosoma mansoni nAChR subunit 0.0112 0.0319 0.1053
Loa Loa (eye worm) hypothetical protein 0.0036 0.0061 0.0061
Mycobacterium ulcerans lipase/esterase 0.0034 0.0054 0.0362
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0019 0.0003 0.0031
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0034 0.0054 0.0527
Brugia malayi UPF0017 protein CG3488 0.0034 0.0054 0.0178
Echinococcus multilocularis neuropeptide receptor 0.0225 0.0707 0.0902
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.035 0.2546
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0019 0.0003 0.0035
Leishmania major hydrolase, alpha/beta fold family, putative 0.0034 0.0054 0.0588
Echinococcus multilocularis G-protein coupled receptor, putative 0.0225 0.0707 0.0902
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0062 0.0605
Schistosoma mansoni biogenic amine (5HT) receptor 0.0225 0.0707 0.2337
Brugia malayi larval opioid receptor 0.0225 0.0707 0.2337
Brugia malayi Isocitrate dehydrogenase 0.0046 0.0093 0.0306
Schistosoma mansoni cellular tumor antigen P53 0.0093 0.0255 0.0844
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.001 0.0032
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0038 0.0066 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0003 0.0011
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0255 0.0325
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.013 0.0383 0.1264
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0112 0.0319 0.0406
Leishmania major serine peptidase, putative,serine peptidase, Clan SC, Family S9D 0.0034 0.0054 0.0588
Brugia malayi hypothetical protein 0.0225 0.0707 0.2337
Mycobacterium tuberculosis Conserved protein 0.0034 0.0054 0.0392
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0019 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Treponema pallidum cyclic nucleotide binding protein 0.0019 0.0003 0.0031
Echinococcus multilocularis dro:myosuppressin receptor 0.0225 0.0707 0.0902
Echinococcus multilocularis fmrfamide receptor 0.0225 0.0707 0.0902
Echinococcus multilocularis expressed conserved protein 0.0019 0.0003 0.0004
Treponema pallidum fructose-bisphosphate aldolase 0.0318 0.1023 1
Brugia malayi mbt repeat family protein 0.0052 0.0114 0.0378
Echinococcus multilocularis sex peptide receptor 0.0225 0.0707 0.0902
Brugia malayi Cyclic-nucleotide gated cation channel 0.0027 0.0029 0.0097
Onchocerca volvulus 0.0059 0.0139 0.1785
Echinococcus multilocularis serotonin receptor 0.0225 0.0707 0.0902
Onchocerca volvulus 0.0153 0.0459 0.5993
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0009 0.0098
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0242 0.0764 0.2525
Loa Loa (eye worm) hypothetical protein 0.013 0.038 0.038
Echinococcus multilocularis serotonin receptor 0.0225 0.0707 0.0902
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0225 0.0707 0.2337
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0046 0.0093 0.0118
Echinococcus multilocularis BC026374 protein (S09 family) 0.0153 0.0459 0.0586
Trypanosoma cruzi hydrolase-like protein, putative 0.0034 0.0054 0.0588
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0019 0.0003 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0242 0.0764 0.2525
Onchocerca volvulus 0.013 0.0383 0.4987
Brugia malayi Serotonin receptor 0.0225 0.0707 0.2337
Onchocerca volvulus 0.0242 0.0764 1
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0242 0.0764 0.0764
Plasmodium falciparum cGMP-dependent protein kinase 0.0019 0.0003 0.0214
Echinococcus multilocularis abhydrolase domain containing protein 11 0.0034 0.0054 0.0069
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0154 0.051
Echinococcus granulosus acetylcholinesterase 0.0905 0.3026 0.7785
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.012 0.0348 0.0444
Loa Loa (eye worm) neuropeptide F receptor 0.0225 0.0707 0.0707
Echinococcus granulosus hyperpolarization activated cyclic 0.0027 0.0029 0.0075
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0027 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.01 0.0279 0.0279
Schistosoma mansoni family S33 non-peptidase homologue (S33 family) 0.0034 0.0054 0.0178
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0092 0.0251 0.0321
Brugia malayi hydrolase, alpha/beta fold family protein 0.0034 0.0054 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0225 0.0707 0.2337
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.001 0.0012
Brugia malayi Cation transporter family protein 0.0242 0.0764 0.2525
Loa Loa (eye worm) hypothetical protein 0.0112 0.0319 0.0319
Brugia malayi Alpha/beta hydrolase 0.0034 0.0054 0.0178
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0034 0.0054 0.0527
Loa Loa (eye worm) hypothetical protein 0.0905 0.3026 0.3026
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0099 0.0326
Loa Loa (eye worm) hypothetical protein 0.0059 0.0139 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0242 0.0764 0.2525
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Loa Loa (eye worm) neuropeptide F receptor 0.0225 0.0707 0.0707
Onchocerca volvulus 0.0062 0.0148 0.1906
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0225 0.0707 0.0902
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0112 0.0319 0.082
Schistosoma mansoni tar DNA-binding protein 0.0127 0.037 0.1223
Echinococcus granulosus g protein coupled receptor 0.0225 0.0707 0.1819
Toxoplasma gondii homoserine O-acetyltransferase, putative 0.0034 0.0054 0.1688
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0242 0.0764 0.0764
Echinococcus multilocularis histone acetyltransferase MYST2 0.0059 0.0139 0.0177
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0144 0.1051
Loa Loa (eye worm) hypothetical protein 0.0242 0.0764 0.0764
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0019 0.0003 0.0008
Brugia malayi hypothetical protein 0.0021 0.001 0.0032
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.003 0.0041 0.0041
Schistosoma mansoni regulator of G protein signaling 0.0021 0.001 0.0032
Echinococcus multilocularis muscleblind protein 0.0302 0.0969 0.1236
Brugia malayi hypothetical protein 0.0062 0.0148 0.049
Onchocerca volvulus Huntingtin homolog 0.013 0.038 0.4957
Mycobacterium ulcerans non-heme haloperoxidase Hpx 0.0034 0.0054 0.0362
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0038 0.0069 0.1406
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0095
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0003 0.0023
Schistosoma mansoni regulator of G protein signaling 0.003 0.0041 0.0134
Trypanosoma cruzi protein kinase A regulatory subunit 0.0019 0.0003 0.0035
Mycobacterium ulcerans hydrolase 0.0034 0.0054 0.0362
Echinococcus multilocularis g protein coupled receptor 0.0225 0.0707 0.0902
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0242 0.0764 0.2525
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0019 0.0003 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0225 0.0707 0.0902
Schistosoma mansoni BC026374 protein (S09 family) 0.0153 0.0459 0.1517
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.0114 0.0146
Brugia malayi Hypothetical 54.7 kDa protein F37A4.1 in chromosome III 0.0034 0.0054 0.0178
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0061 0.0202
Trypanosoma brucei Flagellar Member 6 0.0019 0.0003 0.0035
Brugia malayi glutathione reductase 0.0048 0.01 0.033
Loa Loa (eye worm) hypothetical protein 0.0153 0.0459 0.0459
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0062 0.0205
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0062 0.0451
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0019 0.0003 0.0011
Onchocerca volvulus 0.0225 0.0707 0.9252
Echinococcus multilocularis RUN 0.0062 0.0148 0.0189
Brugia malayi mbt repeat family protein 0.0052 0.0114 0.0378
Echinococcus granulosus tar DNA binding protein 0.0127 0.037 0.0952
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0308 0.2244
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0062 0.1265
Loa Loa (eye worm) hypothetical protein 0.0037 0.0062 0.0062
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0061 0.0667
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0046 0.0093 0.0674
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0061 0.0061
Onchocerca volvulus 0.0225 0.0707 0.9252
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0112 0.0319 0.082
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0009 0.0098
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0144 0.0477
Echinococcus multilocularis dnaJ subfamily B 0.0841 0.2811 0.3586
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.001 0.0012
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0066 0.0084
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0003 0.0031
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.001 0.0032
Mycobacterium leprae Probable homoserine o-acetyltransferase MetA 0.0034 0.0054 0.1092
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0436 0.1439
Schistosoma mansoni neuropeptide receptor 0.0225 0.0707 0.2337
Schistosoma mansoni nAChR subunit 0.0242 0.0764 0.2525
Mycobacterium ulcerans hypothetical protein 0.0019 0.0003 0.0021
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0225 0.0707 0.0902
Echinococcus multilocularis para nitrobenzyl esterase 0.0153 0.0459 0.0586
Leishmania major cyclic nucleotide-binding protein-like protein 0.0019 0.0003 0.0035
Echinococcus multilocularis tar DNA binding protein 0.0127 0.037 0.0472
Onchocerca volvulus 0.0225 0.0707 0.9252
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0153 0.0459 0.3341
Echinococcus granulosus axis inhibition protein axin 0.0021 0.001 0.0025
Mycobacterium ulcerans lipase LipD 0.0037 0.0062 0.0415
Echinococcus multilocularis acetylcholinesterase 0.0905 0.3026 0.3861
Plasmodium vivax multidomain scavenger receptor, putative 0.0062 0.0148 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0225 0.0707 0.0902
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0242 0.0764 0.2525
Echinococcus multilocularis g protein coupled receptor 0.0225 0.0707 0.0902
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1023 1
Trypanosoma cruzi cAMP response protein 1, putative 0.0019 0.0003 0.0035
Loa Loa (eye worm) beta-lactamase 0.0037 0.0062 0.0062
Schistosoma mansoni rab6-interacting 0.0062 0.0148 0.049
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0187 0.1827
Brugia malayi beta-lactamase family protein 0.0037 0.0062 0.0205
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0225 0.0707 0.2337
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0046 0.0093 0.0118
Loa Loa (eye worm) hypothetical protein 0.0148 0.0443 0.0443
Brugia malayi beta-lactamase family protein 0.0037 0.0062 0.0205
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0153 0.0459 0.1517
Echinococcus granulosus expressed protein 0.0414 0.1349 0.3471
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0019 0.0003 0.0004
Loa Loa (eye worm) ACC-1 protein 0.0242 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Brugia malayi Tachykinin-like peptides receptor 99D 0.0225 0.0707 0.2337
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0046 0.0093 0.101
Mycobacterium ulcerans transmembrane transport protein 0.0019 0.0003 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0225 0.0707 0.1819
Schistosoma mansoni histamine h1 receptor 0.0225 0.0707 0.2337
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0242 0.0764 0.0764
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0046 0.0093 0.101
Brugia malayi follicle stimulating hormone receptor 0.0225 0.0707 0.2337
Leishmania major protein kinase, putative 0.0019 0.0003 0.0035
Echinococcus granulosus serotonin receptor 0.0225 0.0707 0.1819
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0225 0.0707 0.2337
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0054 0.0588
Echinococcus granulosus rhodopsin orphan GPCR 0.0225 0.0707 0.1819
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0225 0.0707 0.0902
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0019 0.0003 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0225 0.0707 0.0902
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0242 0.0764 0.0764
Onchocerca volvulus 0.0112 0.0319 0.4146
Schistosoma mansoni pyruvate kinase 0.0036 0.0061 0.0202
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0034 0.0054 0.0527
Echinococcus granulosus abhydrolase domain containing protein 0.0034 0.0054 0.0139
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0242 0.0764 0.2525
Echinococcus granulosus orexin receptor type 2 0.0225 0.0707 0.1819
Schistosoma mansoni nAChR subunit 0.0242 0.0764 0.2525
Loa Loa (eye worm) hypothetical protein 0.0037 0.0062 0.0062
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0112 0.0319 0.1053
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0061 0.1249
Onchocerca volvulus 0.0225 0.0707 0.9252
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0255 0.0255
Echinococcus granulosus glycine receptor subunit beta 0.0242 0.0764 0.1966
Mycobacterium ulcerans hydrolase 0.0034 0.0054 0.0362
Entamoeba histolytica hypothetical protein 0.0146 0.0436 0.4256
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0082 0.021
Echinococcus granulosus neuropeptide s receptor 0.1157 0.3888 1
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Loa Loa (eye worm) RNA binding protein 0.0127 0.037 0.037
Onchocerca volvulus 0.0225 0.0707 0.9252
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0041
Loa Loa (eye worm) latrophilin receptor protein 2 0.0046 0.0096 0.0096
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0003 0.0004
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0019 0.0003 0.0099
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.004 0.0075 0.0818
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.013 0.0383 0.1264
Echinococcus granulosus tumor protein p63 0.0636 0.2111 0.543
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0144 0.0969
Trichomonas vaginalis spcc417.12 protein, putative 0.0153 0.0459 0.4486
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0154 0.0397
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.001 0.0032
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.01 0.01
Loa Loa (eye worm) isocitrate dehydrogenase 0.0046 0.0093 0.0093
Echinococcus multilocularis GPCR, family 2 0.0046 0.0096 0.0122
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0009 0.0098
Schistosoma mansoni pyruvate kinase 0.0019 0.0001 0.0003
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0188 0.024
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.0114 0.0378
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0054
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0242 0.0764 0.2525
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.001 0.0032
Mycobacterium tuberculosis Probable exported protease 0.0034 0.0054 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0095
Brugia malayi hypothetical protein 0.0112 0.0319 0.1053
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0027 0.0029 0.0075
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0034 0.0054 0.0588
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0019 0.0003 0.0004
Schistosoma mansoni nAChR subunit 0.0242 0.0764 0.2525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0225 0.0707 0.2337
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.013 0.0383 0.1264
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus granulosus glycine receptor subunit alpha 1 0.0242 0.0764 0.1966
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0225 0.0707 0.2337
Onchocerca volvulus Neuropeptide F receptor homolog 0.0225 0.0707 0.9252
Brugia malayi Latrophilin receptor protein 2 0.0046 0.0096 0.0316
Loa Loa (eye worm) hypothetical protein 0.013 0.0383 0.0383
Schistosoma mansoni hypothetical protein 0.0187 0.0575 0.1899
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.001 0.0012
Giardia lamblia ENC6 protein 0.0034 0.0054 0.0527
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.0001 0.0057
Brugia malayi CXXC zinc finger family protein 0.0059 0.0139 0.0459
Echinococcus granulosus glycine receptor subunit alpha 1 0.0242 0.0764 0.1966
Plasmodium falciparum acid cluster protein 33 homologue, putative 0.0034 0.0054 0.3639
Leishmania major protein kinase, putative 0.0019 0.0003 0.0035
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0225 0.0707 0.0902
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0019 0.0003 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0095
Schistosoma mansoni acetylcholinesterase 0.0153 0.0459 0.1517
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0019 0.0003 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0062 0.0676
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0019 0.0003 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0255 0.0656
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0242 0.0764 0.0764
Onchocerca volvulus 0.0225 0.0707 0.9252
Entamoeba histolytica hypothetical protein 0.0034 0.0054 0.0527
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0225 0.0707 0.2337
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0112 0.0319 0.0319
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0062 0.0451
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1023 1
Echinococcus granulosus g protein coupled receptor 0.0225 0.0707 0.1819
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0225 0.0707 0.2337
Mycobacterium ulcerans oxidoreductase 0.0034 0.0054 0.0362
Loa Loa (eye worm) hypothetical protein 0.0602 0.1993 0.1993
Trypanosoma cruzi hydrolase-like protein 0.0034 0.0054 0.0588
Echinococcus granulosus Polycystic kidney disease protein 0.0062 0.0148 0.0381
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0062 0.0205
Echinococcus granulosus dna polymerase eta 0.0021 0.0009 0.0023
Mycobacterium ulcerans transcriptional regulatory protein 0.0019 0.0003 0.0021
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0242 0.0764 0.2525
Schistosoma mansoni nAChR subunit 0.0242 0.0764 0.2525
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0019 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0225 0.0707 0.0707
Echinococcus multilocularis abhydrolase domain containing protein 0.0034 0.0054 0.0069
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.0734 0.5341
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0154 0.0197
Onchocerca volvulus 0.0242 0.0764 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0225 0.0707 0.2337
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0019 0.0003 0.0099
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0019 0.0003 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0066 0.0169
Brugia malayi Carboxylesterase family protein 0.0905 0.3026 1
Brugia malayi Carboxylesterase family protein 0.0153 0.0459 0.1517
Leishmania major regulatory subunit of protein kinase a-like protein 0.0019 0.0003 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0009 0.0098
Mycobacterium ulcerans hypothetical protein 0.0034 0.0054 0.0362
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0062 0.0451
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0225 0.0707 0.2337
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0153 0.0459 0.1517
Onchocerca volvulus 0.0225 0.0707 0.9252
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0242 0.0764 0.2525
Plasmodium falciparum alpha/beta hydrolase, putative 0.0034 0.0054 0.3639
Entamoeba histolytica hypothetical protein 0.0146 0.0436 0.4256
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0019 0.0003 0.0214
Echinococcus granulosus nAChR subunit 0.0242 0.0764 0.1966

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = -4.11 Binding affinity to human cloned muscarinic M2 receptor expressed in CHO cells ChEMBL. 18182302

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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