Detailed information for compound 1048822

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 311.718 | Formula: C13H12ClF2N5
  • H donors: 1 H acceptors: 3 LogP: 2.96 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNc1nccc2c1nnn2Cc1c(F)cccc1F.Cl
  • InChi: 1S/C13H11F2N5.ClH/c1-16-13-12-11(5-6-17-13)20(19-18-12)7-8-9(14)3-2-4-10(8)15;/h2-6H,7H2,1H3,(H,16,17);1H
  • InChiKey: RTYSDVIWRYKDSL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0159 0.0847
Toxoplasma gondii LsmAD domain-containing protein 0.018 0.2243 1
Mycobacterium tuberculosis Probable reductase 0.0104 0.1157 0.1198
Brugia malayi Fli-1 protein 0.0238 0.3066 0.4524
Schistosoma mansoni hypothetical protein 0.0071 0.068 0.0583
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.0987 0.0894
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.014 0.0038
Brugia malayi MH1 domain containing protein 0.0033 0.014 0.0058
Echinococcus multilocularis somatostatin receptor 0.0092 0.0987 0.0894
Schistosoma mansoni myosin xvIII 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Loa Loa (eye worm) beta-lactamase 0.0109 0.1228 0.1718
Brugia malayi hypothetical protein 0.0071 0.068 0.0881
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.086 0.0766
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0319 0.1418
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.1157 0.8741
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Echinococcus multilocularis neuropeptide receptor 0.0092 0.0987 0.0894
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0092 0.0987 0.0894
Trypanosoma brucei trypanothione reductase 0.0046 0.0319 0.0793
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0159 0.0113
Trypanosoma brucei PAB1-binding protein , putative 0.018 0.2243 0.5595
Leishmania major hypothetical protein, conserved 0.0109 0.1228 0.3063
Onchocerca volvulus 0.0092 0.0987 0.7856
Brugia malayi Melatonin receptor type 1A 0.0092 0.0987 0.135
Onchocerca volvulus 0.0092 0.0987 0.7856
Loa Loa (eye worm) TAR-binding protein 0.006 0.0519 0.0636
Schistosoma mansoni microtubule-associated protein tau 0.0723 1 1
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0102 0.1128 0.5777
Echinococcus multilocularis neuropeptide s receptor 0.0092 0.0987 0.0894
Schistosoma mansoni amine GPCR 0.0092 0.0987 0.0894
Loa Loa (eye worm) neuropeptide F receptor 0.0092 0.0987 0.135
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni neuropeptide receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni biogenic amine receptor 0.0092 0.0987 0.0894
Echinococcus multilocularis fmrfamide receptor 0.0092 0.0987 0.0894
Echinococcus granulosus fmrfamide receptor 0.0092 0.0987 0.0894
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.1477 0.7565
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) MH2 domain-containing protein 0.0489 0.6654 1
Trichomonas vaginalis esterase, putative 0.0109 0.1228 0.6552
Echinococcus multilocularis sex peptide receptor 0.0092 0.0987 0.0894
Echinococcus multilocularis tumor protein p63 0.0327 0.434 0.4282
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0043 0.0286 0.4205
Echinococcus multilocularis serotonin receptor 0.0334 0.4441 0.4384
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.1228 0.6552
Echinococcus granulosus G protein coupled receptor 139 0.0092 0.0987 0.0894
Echinococcus granulosus Smad4 0.0033 0.014 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Schistosoma mansoni hypothetical protein 0.0255 0.3311 0.3242
Schistosoma mansoni smad1 5 8 and 0.0033 0.014 0.0038
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0275 0.041
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0319 0.0218
Brugia malayi beta-lactamase 0.0109 0.1228 0.1718
Loa Loa (eye worm) hypothetical protein 0.0109 0.1228 0.1718
Brugia malayi G protein-coupled receptor F59B2.13 0.0092 0.0987 0.135
Brugia malayi beta-lactamase family protein 0.0109 0.1228 0.1718
Mycobacterium ulcerans lipase LipD 0.0109 0.1228 0.6289
Loa Loa (eye worm) G-protein coupled receptor 0.0092 0.0987 0.135
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0349 0.0249
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0699 0.9656 1
Onchocerca volvulus 0.0092 0.0987 0.7856
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.014 0.0038
Brugia malayi Serotonin receptor 0.0092 0.0987 0.135
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Loa Loa (eye worm) Smad1 0.0033 0.014 0.0058
Schistosoma mansoni smad1 5 8 and 0.0033 0.014 0.0038
Mycobacterium tuberculosis Conserved protein 0.0109 0.1228 0.1271
Schistosoma mansoni tar DNA-binding protein 0.006 0.0519 0.0421
Loa Loa (eye worm) hypothetical protein 0.0067 0.0622 0.0793
Treponema pallidum hypothetical protein 0.0025 0.0023 1
Echinococcus multilocularis neuropeptide Y receptor 0.0092 0.0987 0.0894
Brugia malayi GnHR receptor homolog 0.0092 0.0987 0.135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.0987 0.0894
Mycobacterium tuberculosis Probable lipase LipE 0.0109 0.1228 0.1271
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Toxoplasma gondii hypothetical protein 0.0049 0.0365 0.1625
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0349 0.0249
Mycobacterium leprae Probable lipase LipE 0.0109 0.1228 0.928
Schistosoma mansoni hypothetical protein 0.0081 0.0821 0.0726
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.172 0.4122
Schistosoma mansoni opsin-like receptor 0.0092 0.0987 0.0894
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.1228 0.2858
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0109 0.1228 0.1718
Schistosoma mansoni hypothetical protein 0.0092 0.0987 0.0894
Schistosoma mansoni alpha-1 adrenergic receptor 0.0092 0.0987 0.0894
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0319 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0676
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.006 0.0519 0.0636
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.0987 0.0894
Brugia malayi ORL1-like opioid receptor 0.0092 0.0987 0.135
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.0126 0.0037
Mycobacterium leprae conserved hypothetical protein 0.0109 0.1228 0.928
Brugia malayi AKH receptor 0.0092 0.0987 0.135
Brugia malayi larval opioid receptor 0.0092 0.0987 0.135
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.1228 0.1137
Brugia malayi Ets-domain containing protein 0.0078 0.0785 0.1041
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0092 0.0987 0.0894
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0109 0.1228 0.1137
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0052 0.041 0.21
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Echinococcus granulosus expressed protein 0.0032 0.0126 0.0024
Schistosoma mansoni Smad4 0.0033 0.014 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0109 0.1228 0.2858
Schistosoma mansoni neuropeptide F-like receptor 0.0092 0.0987 0.0894
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Echinococcus granulosus hypothetical protein 0.0092 0.0987 0.0894
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0127 0.1477 0.1529
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Leishmania major trypanothione reductase 0.0046 0.0319 0.0793
Echinococcus granulosus biogenic amine 5HT receptor 0.0334 0.4441 0.4384
Brugia malayi follicle stimulating hormone receptor 0.0092 0.0987 0.135
Plasmodium vivax glutathione reductase, putative 0.0046 0.0319 0.1418
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0092 0.0987 0.0894
Schistosoma mansoni tar DNA-binding protein 0.006 0.0519 0.0421
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0109 0.1228 0.1271
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Leishmania major mitochondrial DNA polymerase beta 0.0304 0.4009 1
Plasmodium vivax hypothetical protein, conserved 0.0109 0.1228 0.5474
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0043 0.0286 0.0712
Brugia malayi MH1 domain containing protein 0.0033 0.014 0.0058
Onchocerca volvulus 0.0084 0.086 0.6732
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0043 0.0286 0.0186
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0092 0.0987 0.0894
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.1477 0.1389
Onchocerca volvulus 0.0092 0.0987 0.7856
Schistosoma mansoni neuropeptide f receptor 76f 0.0092 0.0987 0.0894
Onchocerca volvulus 0.0092 0.0987 0.7856
Schistosoma mansoni ets-related 0.0238 0.3066 0.2994
Echinococcus granulosus serotonin receptor 0.0092 0.0987 0.0894
Treponema pallidum quinoline 2-oxidoreductase 0.0025 0.0015 0.6355
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.1228 0.6552
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0092 0.0987 0.0894
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0092 0.0987 0.0894
Entamoeba histolytica hypothetical protein 0.0071 0.068 1
Echinococcus granulosus neuropeptide receptor 0.0092 0.0987 0.0894
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.0987 0.0894
Mycobacterium ulcerans esterase/lipase LipP 0.0109 0.1228 0.6289
Brugia malayi putative neuropeptide receptor 0.0092 0.0987 0.135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0195 0.1041
Schistosoma mansoni biogenic amine (5HT) receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.0126 0.0037
Mycobacterium tuberculosis Probable esterase LipL 0.0109 0.1228 0.1271
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.003 0.0086 0.0439
Loa Loa (eye worm) hypothetical protein 0.0109 0.1228 0.1718
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0092 0.0987 0.0894
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0109 0.1228 0.1718
Echinococcus multilocularis g protein coupled receptor 0.0092 0.0987 0.0894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0286 0.1526
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni gabp alpha 0.0078 0.0785 0.0689
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0092 0.0987 0.0894
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.1157 0.1198
Echinococcus multilocularis neuropeptide receptor 0.0092 0.0987 0.0894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0676
Brugia malayi Smad1 0.0033 0.014 0.0058
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.014 0.0058
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0092 0.0987 0.0894
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0092 0.0987 0.0894
Mycobacterium ulcerans hypothetical protein 0.016 0.1953 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Plasmodium vivax ataxin-2 like protein, putative 0.018 0.2243 1
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0092 0.0987 0.0894
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0116 0.1693
Brugia malayi Dopamine receptor protein 1 0.0092 0.0987 0.135
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0073 0.0706 0.3616
Echinococcus granulosus biogenic amine 5HT receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni tar DNA-binding protein 0.006 0.0519 0.0421
Loa Loa (eye worm) hypothetical protein 0.0109 0.1228 0.1718
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni opsin-like receptor 0.0092 0.0987 0.0894
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0092 0.0987 0.0894
Schistosoma mansoni growth hormone secretagogue receptor 0.0092 0.0987 0.0894
Echinococcus multilocularis neuropeptide FF receptor 2 0.0092 0.0987 0.0894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0036 0.0191
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0092 0.0987 0.0894
Schistosoma mansoni amine GPCR 0.0092 0.0987 0.0894
Brugia malayi G protein-coupled receptor 0.0092 0.0987 0.135
Echinococcus granulosus neuropeptide Y receptor 0.0092 0.0987 0.0894
Giardia lamblia GTOR 0.0043 0.0286 0.5
Loa Loa (eye worm) glutathione reductase 0.0046 0.0319 0.033
Echinococcus granulosus 7TM GPCR rhodopsin 0.0092 0.0987 0.0894
Echinococcus multilocularis G protein coupled receptor 139 0.0092 0.0987 0.0894
Echinococcus multilocularis serotonin receptor 0.0334 0.4441 0.4384
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.4009 1
Loa Loa (eye worm) hypothetical protein 0.0109 0.1228 0.1718
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0092 0.0987 0.135
Echinococcus granulosus neuropeptide FF receptor 2 0.0092 0.0987 0.0894
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0349 0.0249
Brugia malayi beta-lactamase family protein 0.0109 0.1228 0.1718
Schistosoma mansoni rotamase 0.0032 0.0126 0.0024
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0092 0.0987 0.135
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0304 0.4009 1
Trichomonas vaginalis aldehyde oxidase, putative 0.0155 0.1875 1
Echinococcus granulosus tar DNA binding protein 0.006 0.0519 0.0421
Loa Loa (eye worm) hypothetical protein 0.0334 0.4441 0.6622
Loa Loa (eye worm) RNA binding protein 0.006 0.0519 0.0636
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0073 0.0706 0.0731
Brugia malayi G-protein coupled receptor 0.0092 0.0987 0.135
Toxoplasma gondii ABC1 family protein 0.0109 0.1228 0.5474
Brugia malayi Dopamine receptor protein 2 0.0092 0.0987 0.135
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0092 0.0987 0.0894
Schistosoma mansoni hypothetical protein 0.0092 0.0987 0.0894
Plasmodium falciparum thioredoxin reductase 0.0046 0.0319 0.1418
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0043 0.0286 0.0438
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Trichomonas vaginalis penicillin-binding protein, putative 0.0109 0.1228 0.6552
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0319 0.0329
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.1157 0.1198
Onchocerca volvulus 0.0092 0.0987 0.7856
Onchocerca volvulus 0.0109 0.1228 1
Echinococcus multilocularis g protein coupled receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Onchocerca volvulus 0.0092 0.0987 0.7856
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0127 0.1477 0.1389
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0046 0.0319 0.1633
Echinococcus multilocularis expressed protein 0.0032 0.0126 0.0024
Loa Loa (eye worm) hypothetical protein 0.0109 0.1228 0.1718
Schistosoma mansoni biogenic amine receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.003 0.0086 0.0439
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.014 0.0038
Echinococcus multilocularis neuropeptides capa receptor 0.0092 0.0987 0.0894
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0109 0.1228 0.1271
Echinococcus multilocularis microtubule associated protein 2 0.0723 1 1
Toxoplasma gondii thioredoxin reductase 0.0046 0.0319 0.1418
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0349 0.0249
Echinococcus multilocularis tar DNA binding protein 0.006 0.0519 0.0421
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0001 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0032 0.0171
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0286 0.1526
Mycobacterium ulcerans beta-lactamase 0.0109 0.1228 0.6289
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.4009 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0092 0.0987 0.135
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.1228 0.6552
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0081 0.0821 0.0726
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.1477 0.7565
Schistosoma mansoni neuropeptide receptor 0.0092 0.0987 0.0894
Schistosoma mansoni tar DNA-binding protein 0.006 0.0519 0.0421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0036 0.0191
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni tar DNA-binding protein 0.006 0.0519 0.0421
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.003 0.0086 0.0089
Entamoeba histolytica hypothetical protein 0.0071 0.068 1
Brugia malayi neuropeptide F receptor 0.0092 0.0987 0.135
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0409 0.0753
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0109 0.1228 0.1718
Echinococcus multilocularis G-protein coupled receptor, putative 0.0092 0.0987 0.0894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0032 0.0171
Loa Loa (eye worm) melatonin receptor type 1A 0.0092 0.0987 0.135
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0255 0.3311 0.3242
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0043 0.0286 0.0712
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.0987 0.0894
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0116 0.0287
Echinococcus granulosus beta LACTamase domain containing family member 0.0109 0.1228 0.1137
Brugia malayi Dopamine receptor 0.0092 0.0987 0.135
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0001 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0126 0.0674
Schistosoma mansoni amine GPCR 0.0092 0.0987 0.0894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0676
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.0987 0.0894
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0043 0.0286 0.0438
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0286 0.1526
Schistosoma mansoni adenoreceptor 0.0092 0.0987 0.0894
Echinococcus multilocularis neuropeptide Y receptor 0.0092 0.0987 0.0894
Echinococcus multilocularis thyroid hormone receptor alpha 0.0286 0.375 0.3685
Echinococcus multilocularis allatostatin A receptor 0.0092 0.0987 0.0894
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0052 0.041 0.0424
Entamoeba histolytica hypothetical protein 0.0071 0.068 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0159 0.0847
Loa Loa (eye worm) phosphatidylinositol 3 0.0043 0.0286 0.028
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Brugia malayi MH2 domain containing protein 0.0033 0.014 0.0058
Schistosoma mansoni thyroid hormone receptor 0.0286 0.375 0.3685
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.086 0.0766
Onchocerca volvulus 0.0092 0.0987 0.7856
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0275 0.041
Echinococcus multilocularis smad 0.0033 0.014 0.0038
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0043 0.0286 0.0186
Onchocerca volvulus 0.0109 0.1228 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.0987 0.0894
Entamoeba histolytica hypothetical protein 0.0071 0.068 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0092 0.0987 0.0894
Plasmodium falciparum ataxin-2 like protein, putative 0.018 0.2243 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0092 0.0987 0.0894
Brugia malayi TAR-binding protein 0.006 0.0519 0.0636
Loa Loa (eye worm) hypothetical protein 0.0048 0.0349 0.0376
Onchocerca volvulus 0.0092 0.0987 0.7856
Schistosoma mansoni histamine h1 receptor 0.0092 0.0987 0.0894
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Brugia malayi glutathione reductase 0.0046 0.0319 0.033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.0987 0.0894
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0043 0.0286 0.0712
Schistosoma mansoni opsin-like receptor 0.0092 0.0987 0.0894
Mycobacterium tuberculosis Conserved protein 0.0109 0.1228 0.1271
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.1157 0.1198
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni biogenic amine receptor 0.0092 0.0987 0.0894
Trypanosoma cruzi PAB1-binding protein , putative 0.018 0.2243 0.5465
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.0987 0.0894
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0092 0.0987 0.0894
Echinococcus granulosus neuropeptide receptor 0.0092 0.0987 0.0894
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0092 0.0987 0.135
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0109 0.1228 0.6289
Echinococcus granulosus orexin receptor type 2 0.0092 0.0987 0.0894
Echinococcus multilocularis fmrfamide receptor 0.0092 0.0987 0.0894
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.1157 0.1198
Trypanosoma cruzi PAB1-binding protein , putative 0.018 0.2243 0.5465
Onchocerca volvulus 0.0092 0.0987 0.7856
Plasmodium falciparum ataxin-2 like protein, putative 0.018 0.2243 1
Onchocerca volvulus 0.0092 0.0987 0.7856
Loa Loa (eye worm) hypothetical protein 0.0084 0.086 0.1157
Echinococcus granulosus allatostatin A receptor 0.0092 0.0987 0.0894
Mycobacterium ulcerans hypothetical protein 0.0109 0.1228 0.6289
Plasmodium falciparum glutathione reductase 0.0046 0.0319 0.1418
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0275 0.0685
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0081 0.0821 0.0726
Mycobacterium ulcerans hypothetical protein 0.0025 0.0023 0.0117
Brugia malayi MH2 domain containing protein 0.0489 0.6654 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0676
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0068 0.0362
Schistosoma mansoni aldehyde dehydrogenase 0.0127 0.1477 0.1389
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0043 0.0286 0.0712
Schistosoma mansoni amine GPCR 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.018 0.2243 0.3267
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.068 0.0583
Onchocerca volvulus 0.0092 0.0987 0.7856
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0275 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0159 0.0847
Schistosoma mansoni hypothetical protein 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Brugia malayi Ets-domain containing protein 0.0078 0.0785 0.1041
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0159 0.0396
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0127 0.0563
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.014 0.0038
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0319 0.0521
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0116 0.0287
Mycobacterium tuberculosis Conserved protein 0.0109 0.1228 0.1271
Brugia malayi Serotonin receptor 0.0092 0.0987 0.135
Onchocerca volvulus 0.0048 0.0349 0.2187
Brugia malayi hypothetical protein 0.018 0.2243 0.3267
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.086 0.1157
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0092 0.0987 0.135
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0092 0.0987 0.135
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0155 0.1875 1
Brugia malayi putative neuropeptide receptor NPR1 0.0092 0.0987 0.135
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.068 0.0583
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.014 0.0038
Schistosoma mansoni thyroid hormone receptor 0.0286 0.375 0.3685
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0676
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0159 0.0396
Schistosoma mansoni smad 0.0033 0.014 0.0038
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0127 0.1477 0.3684
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0676
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.068 0.0583
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.0987 0.0894
Onchocerca volvulus 0.0092 0.0987 0.7856
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.086 0.0766
Echinococcus granulosus neuropeptide receptor A26 0.0092 0.0987 0.0894
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0127 0.1477 0.1389
Echinococcus granulosus neuropeptide s receptor 0.0092 0.0987 0.0894
Echinococcus granulosus sex peptide receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0092 0.0987 0.135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0036 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0081 0.0434
Schistosoma mansoni biogenic amine (5HT) receptor 0.0334 0.4441 0.4384
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0349 0.0249
Brugia malayi hypothetical protein 0.0116 0.1329 0.1872
Echinococcus multilocularis Smad4 0.0033 0.014 0.0038
Brugia malayi RNA binding protein 0.006 0.0519 0.0636
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Echinococcus granulosus peptide allatostatin:somatostatin 0.0092 0.0987 0.0894
Brugia malayi Tachykinin-like peptides receptor 99D 0.0092 0.0987 0.135
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Mycobacterium tuberculosis Probable lipase LipD 0.0109 0.1228 0.1271
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0319 0.033
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Echinococcus multilocularis GA binding protein alpha chain 0.0078 0.0785 0.0689
Brugia malayi RE15519p 0.0092 0.0987 0.135
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0092 0.0987 0.0894
Echinococcus granulosus neuropeptides capa receptor 0.0092 0.0987 0.0894
Echinococcus granulosus somatostatin receptor 0.0092 0.0987 0.0894
Echinococcus granulosus g protein coupled receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Onchocerca volvulus 0.0092 0.0987 0.7856
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.1157 0.1198
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0052 0.041 0.21
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Mycobacterium ulcerans aldehyde dehydrogenase 0.0127 0.1477 0.7565
Toxoplasma gondii aldehyde dehydrogenase 0.0127 0.1477 0.6585
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Echinococcus granulosus 7tm_1 domain containing protein 0.0092 0.0987 0.0894
Onchocerca volvulus Neuropeptide F receptor homolog 0.0092 0.0987 0.7856
Echinococcus granulosus g protein coupled receptor 0.0092 0.0987 0.0894
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0109 0.1228 0.1271
Brugia malayi Thioredoxin reductase 0.0046 0.0319 0.033
Echinococcus multilocularis neuropeptides capa receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) fli-1 protein 0.0238 0.3066 0.4524
Leishmania major hypothetical protein, conserved 0.018 0.2243 0.5595
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0092 0.0987 0.0894
Echinococcus multilocularis orexin receptor type 2 0.0092 0.0987 0.0894
Schistosoma mansoni amine GPCR 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0043 0.0286 0.028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Brugia malayi MH2 domain containing protein 0.0033 0.014 0.0058
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.1323 0.137
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.0987 0.0894
Onchocerca volvulus 0.0092 0.0987 0.7856
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0073 0.0706 0.3616
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0092 0.0987 0.0894
Trichomonas vaginalis rotamase, putative 0.0032 0.0116 0.0616
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0155 0.1875 1
Echinococcus multilocularis g protein coupled receptor 0.0092 0.0987 0.0894
Echinococcus granulosus alpha 1A adrenergic receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) transcription factor SMAD2 0.0489 0.6654 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.0987 0.0894
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.1323 1
Brugia malayi G-protein coupled receptor 0.0092 0.0987 0.135
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Echinococcus granulosus g-protein coupled receptor 0.0092 0.0987 0.0894
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.172 0.4291
Brugia malayi sulfakinin receptor protein 0.0092 0.0987 0.135
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0092 0.0987 0.0894
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0092 0.0987 0.7856
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0092 0.0987 0.135
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.172 0.4291
Onchocerca volvulus 0.0092 0.0987 0.7856
Trichomonas vaginalis D-aminoacylase, putative 0.0109 0.1228 0.6552
Echinococcus multilocularis beta LACTamase domain containing family member 0.0109 0.1228 0.1137
Echinococcus granulosus g protein coupled receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0349 0.0377
Schistosoma mansoni hypothetical protein 0.0092 0.0987 0.0894
Echinococcus multilocularis g-protein coupled receptor 0.0092 0.0987 0.0894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0159 0.0847
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.0987 0.0894
Trichomonas vaginalis rotamase, putative 0.0032 0.0126 0.0674
Echinococcus granulosus neuropeptide Y receptor 0.0092 0.0987 0.0894
Echinococcus granulosus neuropeptides capa receptor 0.0092 0.0987 0.0894
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0092 0.0987 0.0894
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0092 0.0987 0.135
Loa Loa (eye worm) hypothetical protein 0.0334 0.4441 0.6622
Trypanosoma brucei hypothetical protein, conserved 0.0109 0.1228 0.3063
Schistosoma mansoni neuropeptide receptor 0.0092 0.0987 0.0894
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0349 0.0377
Loa Loa (eye worm) G-protein coupled receptor 0.0092 0.0987 0.135
Mycobacterium tuberculosis Probable hydrolase 0.0109 0.1228 0.1271
Schistosoma mansoni neuropeptide F-like receptor 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0078 0.0785 0.1041
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0349 0.0249
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.1323 0.137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0127 0.0676
Schistosoma mansoni smad1 5 8 and 0.0033 0.014 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0349 0.0249
Loa Loa (eye worm) TYRA-2 protein 0.0092 0.0987 0.135
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.1323 0.137
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.0987 0.0894
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0159 0.0847
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Echinococcus multilocularis neuropeptide receptor A26 0.0092 0.0987 0.0894
Loa Loa (eye worm) hypothetical protein 0.0092 0.0987 0.135
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.0987 0.0894
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.014 0.0058
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0092 0.0987 0.0894
Brugia malayi RNA recognition motif domain containing protein 0.006 0.0519 0.0636
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0092 0.0987 0.0894
Echinococcus granulosus dro:myosuppressin receptor 0.0092 0.0987 0.0894
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.0987 0.0894
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0092 0.0987 0.135
Brugia malayi neuropeptide F receptor 0.0092 0.0987 0.135
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0116 0.0513
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0255 0.3311 0.3242
Loa Loa (eye worm) neuropeptide F receptor 0.0092 0.0987 0.135
Echinococcus granulosus GA binding protein alpha chain 0.0078 0.0785 0.0689
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.0987 0.0894
Brugia malayi hypothetical protein 0.0092 0.0987 0.135
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0043 0.0286 0.0186
Mycobacterium tuberculosis Conserved hypothetical protein 0.016 0.1953 0.2022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0349 0.0249
Onchocerca volvulus 0.0092 0.0987 0.7856
Echinococcus granulosus tumor protein p63 0.0327 0.434 0.4282
Onchocerca volvulus 0.0109 0.1228 1
Schistosoma mansoni neuropeptide receptor 0.0092 0.0987 0.0894
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0043 0.0286 0.4205
Echinococcus granulosus smad 0.0033 0.014 0.0038

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.