Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | voltage gated potassium channel | 0.0011 | 0.1028 | 0.1145 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0019 | 0.3338 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.2734 | 0.2734 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0017 | 0.2734 | 0.3047 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0014 | 0.1934 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.7495 | 0.8354 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.2734 | 0.2734 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | g-protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | orexin receptor type 2 | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.3338 | 0.372 |
Echinococcus granulosus | sex peptide receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.5217 | 0.5814 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.5217 | 0.5814 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | allatostatin A receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.1934 | 0.2156 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0014 | 0.1934 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | Melatonin receptor type 1A | 0.0017 | 0.2734 | 0.3047 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0019 | 0.3338 | 0.5 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0017 | 0.2734 | 0.2734 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0039 | 0.8972 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.2734 | 0.2734 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | voltage gated potassium channel | 0.0011 | 0.1028 | 0.1145 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0017 | 0.2734 | 0.2734 |
Brugia malayi | AMP-binding enzyme family protein | 0.0019 | 0.3338 | 0.372 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0019 | 0.3338 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1028 | 0.1145 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0019 | 0.3338 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.1934 | 0.2156 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0017 | 0.2734 | 0.2734 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.5217 | 0.5814 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.5217 | 0.5814 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.8236 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | allatostatin A receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1372 | 0.153 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.5217 | 0.5217 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0019 | 0.3338 | 0.5 |
Onchocerca volvulus | 0.0026 | 0.5217 | 1 | |
Schistosoma mansoni | adenoreceptor | 0.0017 | 0.2734 | 0.2734 |
Echinococcus granulosus | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.2734 | 0.2734 |
Onchocerca volvulus | 0.0026 | 0.5217 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | AMP-binding enzyme family protein | 0.0019 | 0.3338 | 0.372 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | larval opioid receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0019 | 0.3338 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0039 | 0.8972 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.2734 | 0.2734 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | lamin | 0.0026 | 0.5217 | 0.5217 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.5217 | 0.5814 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0014 | 0.1934 | 0.139 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.5217 | 0.5814 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0019 | 0.3338 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0039 | 0.8972 | 1 |
Echinococcus multilocularis | musashi | 0.0026 | 0.5217 | 0.5814 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.3338 | 0.372 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0019 | 0.3338 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0019 | 0.3338 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.1028 | 0.1028 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0011 | 0.1028 | 0.1145 |
Brugia malayi | RE15519p | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.1934 | 0.2156 |
Echinococcus granulosus | lamin | 0.0026 | 0.5217 | 0.5814 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | G protein-coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.2734 | 0.2734 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0019 | 0.3338 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.1767 | 0.1969 |
Brugia malayi | sulfakinin receptor protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0011 | 0.1028 | 0.1145 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.2734 | 0.2734 |
Brugia malayi | ORL1-like opioid receptor | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.2734 | 0.2734 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0014 | 0.1934 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.2734 | 0.2734 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | Dopamine receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.1934 | 0.2156 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | AMP-binding enzyme family protein | 0.0019 | 0.3338 | 0.372 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0012 | 0.1372 | 0.153 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0012 | 0.1372 | 0.153 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0011 | 0.1028 | 0.1028 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.2734 | 0.2734 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | somatostatin receptor | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.3338 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Onchocerca volvulus | 0.0019 | 0.3338 | 0.243 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0043 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | GnHR receptor homolog | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | Dopamine receptor protein 2 | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.2734 | 0.2734 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0017 | 0.2734 | 0.2734 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0017 | 0.2734 | 0.2734 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0017 | 0.2734 | 0.3047 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0019 | 0.3338 | 0.5 |
Echinococcus granulosus | neuropeptide s receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.3338 | 0.372 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.1767 | 0.1969 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.5081 | 0.5662 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | follicle stimulating hormone receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.2734 | 0.2734 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.5217 | 0.5814 |
Schistosoma mansoni | myosin xvIII | 0.0017 | 0.2734 | 0.2734 |
Echinococcus granulosus | serotonin receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0019 | 0.3338 | 1 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | somatostatin receptor | 0.0017 | 0.2734 | 0.3047 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0019 | 0.3338 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.2734 | 0.2734 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0011 | 0.1028 | 0.1145 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.5217 | 0.5814 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1236 | 0.1378 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | putative neuropeptide receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | histamine h1 receptor | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.2734 | 0.3047 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.8236 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0039 | 0.8972 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | AKH receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | fmrfamide receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.1934 | 0.2156 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.2734 | 0.2734 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0017 | 0.2734 | 0.2734 |
Echinococcus multilocularis | lamin | 0.0026 | 0.5217 | 0.5814 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.2734 | 0.2734 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | sex peptide receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1236 | 0.1378 |
Brugia malayi | Dopamine receptor protein 1 | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0017 | 0.2734 | 0.2734 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0019 | 0.3338 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.2734 | 0.2734 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0017 | 0.2734 | 0.3047 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0019 | 0.3338 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.2734 | 0.2734 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | lamin | 0.0026 | 0.5217 | 0.5217 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0017 | 0.2734 | 0.3047 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0019 | 0.3338 | 1 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2734 | 0.3047 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.2734 | 0.3047 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0017 | 0.2734 | 0.3047 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0019 | 0.3338 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.2734 | 0.2734 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.2734 | 0.2734 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.2734 | 0.3047 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.2734 | 0.3047 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 16 % | DNDI: Inhibition of Human African Trypanosomiasis, SBRI 427, in vitro at 2 ug.mL-1 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.