Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.4393 | 0.5396 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.0453 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.4678 | 0.6015 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.3781 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4678 | 0.4619 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.7357 | 1 |
Brugia malayi | hypothetical protein | 0.0017 | 0.2226 | 0.2029 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.7357 | 0.7328 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4678 | 0.4619 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.0453 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.7357 | 0.7328 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3781 | 0.4428 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.7357 | 0.7328 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.7357 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.7357 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.7357 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.7357 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.7357 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.1361 | 0.108 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.1361 | 0.108 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.4678 | 0.6015 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0525 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.3781 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 1 |
Brugia malayi | hypothetical protein | 0.0026 | 0.3781 | 0.4445 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.1361 | 0.1265 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.3781 | 0.5 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.4393 | 0.5381 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.3781 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.3781 | 0.5 |
Onchocerca volvulus | 0.0029 | 0.4393 | 0.5 | |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.4393 | 0.4331 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.8867 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.3781 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.3781 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0531 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.