Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0126 | 0.1494 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0025 | 0.0125 | 0.0148 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0025 | 0.0125 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0344 | 0.4475 | 0.7601 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0111 | 0.0093 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0449 | 0.0644 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0025 | 0.0125 | 0.0107 |
Onchocerca volvulus | 0.0344 | 0.4475 | 0.6649 | |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0936 | 0.3976 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0085 | 0.0936 | 0.1726 |
Schistosoma mansoni | SET domain protein | 0.0019 | 0.0043 | 0.0025 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0023 | 0.0089 | 0.0106 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0097 | 0.1101 | 0.2321 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.0936 | 0.092 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0126 | 0.1494 | 0.6391 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0049 | 0.0449 | 0.0644 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0068 | 0.0708 | 0.0691 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0413 | 0.5423 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0449 | 0.0644 |
Trypanosoma cruzi | ISWI complex protein | 0.0023 | 0.0089 | 0.011 |
Echinococcus granulosus | dna polymerase kappa | 0.0156 | 0.1908 | 0.1893 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0038 | 0.0223 |
Trypanosoma brucei | phosphatidylinositol (3,5) kinase, putative | 0.0028 | 0.0154 | 0.0253 |
Trypanosoma brucei | ISWI complex protein | 0.0023 | 0.0089 | 0.011 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0186 | 0.2327 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0029 | 0.0177 | 0.1863 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0049 | 0.0449 | 0.0644 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0126 | 0.1494 | 0.2493 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0038 | 0.0089 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0168 | 0.2068 | 0.4433 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0154 | 0.0253 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0026 | 0.0138 | 0.0179 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0056 | 0.0545 | 0.0528 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0056 | 0.0537 | 0.2247 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0038 | 0.0031 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0936 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0425 | 0.0408 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0056 | 0.0537 | 0.052 |
Plasmodium falciparum | zinc finger protein, putative | 0.0026 | 0.0127 | 0.0987 |
Echinococcus multilocularis | Smad4 | 0.0025 | 0.0125 | 0.0107 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0449 | 0.0644 |
Toxoplasma gondii | hypothetical protein | 0.0057 | 0.0558 | 0.1029 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0217 | 0.274 | 0.4629 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0724 | 0.1175 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0449 | 0.0644 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0068 | 0.0708 | 0.0691 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0038 | 0.0383 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0056 | 0.0545 | 0.0528 |
Echinococcus multilocularis | cpg binding protein | 0.0229 | 0.2909 | 0.2896 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0033 | 0.0234 | 0.0217 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0425 | 0.0663 |
Giardia lamblia | DNA damage repair protein | 0.0039 | 0.031 | 0.1744 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0748 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.031 | 0.0593 |
Trypanosoma brucei | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0154 | 0.0253 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0183 | 0.2285 | 0.4905 |
Brugia malayi | Pre-SET motif family protein | 0.0068 | 0.0708 | 0.1146 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0126 | 0.1494 | 0.1478 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0038 | 0.0031 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0936 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0936 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.2285 | 0.3849 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0111 | 0.0138 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0133 | 0.1596 | 0.3402 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0046 | 0.0413 | 0.0761 |
Giardia lamblia | DINP protein human, muc B family | 0.0133 | 0.1596 | 1 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0025 | 0.0125 | 0.0107 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0111 | 0.0124 |
Echinococcus multilocularis | dna polymerase eta | 0.0183 | 0.2285 | 0.2271 |
Brugia malayi | Pip kinase protein 2 | 0.0344 | 0.4475 | 0.7601 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0154 | 0.0253 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0133 | 0.1596 | 0.3402 |
Trypanosoma brucei | phosphatidylinositol phosphate kinase alpha | 0.0028 | 0.0154 | 0.0253 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0936 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0125 | 0.0148 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0049 | 0.0449 | 0.0644 |
Trypanosoma brucei | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0154 | 0.0253 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Schistosoma mansoni | cpg binding protein | 0.0229 | 0.2909 | 0.2896 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0061 | 0.0607 | 0.1242 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0449 | 0.0644 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0232 | 0.2955 | 0.2942 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0125 | 0.0148 |
Brugia malayi | Pre-SET motif family protein | 0.0446 | 0.5875 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0373 | 0.4874 | 0.8284 |
Toxoplasma gondii | hypothetical protein | 0.0029 | 0.0177 | 0.0326 |
Plasmodium vivax | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0154 | 0.1627 |
Brugia malayi | Probable ClpP-like protease | 0.0085 | 0.0936 | 0.1538 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1592 | 0.2662 |
Trichomonas vaginalis | phosphatidylinositol-4-phosphate 5-kinase type II, putative | 0.0028 | 0.0154 | 0.0204 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0068 | 0.0708 | 0.0691 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0039 | 0.031 | 0.0593 |
Echinococcus granulosus | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0344 | 0.4475 | 0.4465 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0936 | 0.1538 |
Onchocerca volvulus | Huntingtin homolog | 0.0133 | 0.1592 | 0.2324 |
Echinococcus multilocularis | smad | 0.0025 | 0.0125 | 0.0107 |
Brugia malayi | MH2 domain containing protein | 0.0373 | 0.4874 | 0.8284 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0039 | 0.031 | 0.3294 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.005 | 0.0458 | 0.0916 |
Schistosoma mansoni | Smad4 | 0.0025 | 0.0125 | 0.0107 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0025 | 0.0125 | 0.0107 |
Leishmania major | DNA polymerase eta, putative | 0.0097 | 0.1101 | 0.2321 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0133 | 0.1596 | 0.6836 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.004 | 0.0023 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0029 | 0.0177 | 0.154 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate-5-kinaseputativ e | 0.0028 | 0.0154 | 0.0137 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0183 | 0.2285 | 0.4905 |
Schistosoma mansoni | cpg binding protein | 0.0229 | 0.2909 | 0.2896 |
Loa Loa (eye worm) | histone methyltransferase | 0.0069 | 0.0726 | 0.1178 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0168 | 0.2068 | 0.4433 |
Leishmania major | phosphatidylinositol (3,5) kinase, putative | 0.0028 | 0.0154 | 0.0253 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0126 | 0.1494 | 0.1478 |
Trypanosoma brucei | unspecified product | 0.0148 | 0.1805 | 0.3858 |
Toxoplasma gondii | phosphatidylinositol-4-phosphate 5-Kinase | 0.0028 | 0.0154 | 0.0285 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0038 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1592 | 0.2662 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0183 | 0.2285 | 0.3849 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0449 | 0.0644 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0049 | 0.0449 | 0.0644 |
Echinococcus granulosus | smad | 0.0025 | 0.0125 | 0.0107 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.0154 | 0.1627 |
Leishmania major | phosphatidylinositol-4-phosphate-5-kinase-likep ro tein | 0.0028 | 0.0154 | 0.0253 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0354 | 0.4618 | 1 |
Trypanosoma cruzi | phosphatidylinositol 4-phosphate 5-kinase alpha, putative | 0.0028 | 0.0154 | 0.0253 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0462 | 0.6094 | 0.6087 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0069 | 0.0724 | 0.1498 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Leishmania major | DNA polymerase eta, putative | 0.0183 | 0.2285 | 0.4905 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0373 | 0.4874 | 0.8284 |
Trichomonas vaginalis | set domain proteins, putative | 0.0507 | 0.6709 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0229 | 0.2909 | 0.2896 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0126 | 0.1494 | 0.1478 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0126 | 0.1494 | 0.2493 |
Trichomonas vaginalis | hypothetical protein | 0.0026 | 0.0138 | 0.0179 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0068 | 0.0708 | 0.0691 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0156 | 0.1908 | 0.8184 |
Echinococcus multilocularis | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0344 | 0.4475 | 0.4465 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0038 | 0.002 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0354 | 0.4618 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0354 | 0.4618 | 1 |
Brugia malayi | SET domain containing protein | 0.0019 | 0.0043 | 0.0008 |
Brugia malayi | hypothetical protein | 0.0133 | 0.1592 | 0.2662 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0068 | 0.0708 | 0.1305 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0039 | 0.031 | 0.0593 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0748 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0708 | 0.1146 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0168 | 0.2068 | 0.4433 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.0138 | 0.0179 |
Mycobacterium ulcerans | hypothetical protein | 0.0186 | 0.2327 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0056 | 0.0545 | 0.0528 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.031 | 0.0593 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0039 | 0.031 | 0.0593 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0085 | 0.0936 | 0.1726 |
Schistosoma mansoni | myst-related protein | 0.0026 | 0.0127 | 0.0109 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0094 | 0.1064 | 0.2239 |
Echinococcus granulosus | Phosphatidylinositol 4 phosphate 5 kinase type 1 | 0.0028 | 0.0154 | 0.0137 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0085 | 0.0936 | 0.092 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0056 | 0.0537 | 0.5652 |
Echinococcus multilocularis | phosphatidylinositol phosphate 5 kinase type III | 0.0028 | 0.0154 | 0.0137 |
Brugia malayi | FYVE finger-containing phosphoinositide kinase, putative | 0.0028 | 0.0154 | 0.0199 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0069 | 0.0726 | 0.0709 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0449 | 0.0644 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0038 | 0.0223 |
Leishmania major | DNA damage repair protein, putative | 0.0039 | 0.031 | 0.0593 |
Trypanosoma cruzi | phosphatidylinositol (3,5) kinase, putative | 0.0028 | 0.0154 | 0.0253 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0425 | 0.0408 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0039 | 0.031 | 0.0293 |
Brugia malayi | Smad1 | 0.0025 | 0.0125 | 0.0148 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type I | 0.0028 | 0.0154 | 0.0137 |
Trypanosoma brucei | unspecified product | 0.0087 | 0.0961 | 0.2015 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0156 | 0.1908 | 0.4082 |
Brugia malayi | CXXC zinc finger family protein | 0.0217 | 0.274 | 0.4629 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1454 | 0.2425 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0936 | 1 |
Toxoplasma gondii | phosphatidylinositol-4-phosphate 5-kinase | 0.0028 | 0.0154 | 0.0285 |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.031 | 0.1265 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0354 | 0.4618 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0127 | 0.0609 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase-like, putative | 0.0028 | 0.0154 | 0.0253 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0038 | 0.002 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0061 | 0.0611 | 0.0594 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0069 | 0.0714 | 0.1158 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0029 | 0.0177 | 0.1728 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0126 | 0.1494 | 0.1478 |
Plasmodium vivax | SET domain protein, putative | 0.0068 | 0.0708 | 0.7553 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Echinococcus multilocularis | dna polymerase kappa | 0.0156 | 0.1908 | 0.1893 |
Entamoeba histolytica | phosphoinositide kinase, putative | 0.0028 | 0.0154 | 0.0798 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase type II beta, putative | 0.0028 | 0.0154 | 0.0253 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0094 | 0.1064 | 0.2239 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0232 | 0.2955 | 0.2942 |
Loa Loa (eye worm) | pip kinase 1 | 0.0028 | 0.0154 | 0.0199 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0056 | 0.0545 | 0.0528 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0344 | 0.4475 | 0.4465 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0049 | 0.0449 | 0.0644 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0025 | 0.0125 | 0.0107 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase-like, putative | 0.0028 | 0.0154 | 0.0253 |
Schistosoma mansoni | cpg binding protein | 0.0217 | 0.274 | 0.2727 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0028 | 0.0154 | 0.0137 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0056 | 0.0537 | 0.2247 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.031 | 0.0593 |
Entamoeba histolytica | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0154 | 0.0798 |
Trypanosoma brucei | unspecified product | 0.0087 | 0.0961 | 0.2015 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0085 | 0.0936 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.031 | 0.0593 |
Leishmania major | phosphatidylinositol-4-phosphate 5-kinase-like protein | 0.0028 | 0.0154 | 0.0253 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0111 | 0.0124 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0038 | 0.002 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0936 | 0.3976 |
Schistosoma mansoni | DNA polymerase eta | 0.0183 | 0.2285 | 0.2271 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0028 | 0.0154 | 0.0137 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0038 | 0.0089 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0125 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.2955 | 0.4996 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0068 | 0.0708 | 0.0691 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0125 | 0.0107 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0069 | 0.0724 | 0.1498 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0069 | 0.0726 | 0.0709 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0089 | 0.0106 |
Leishmania major | phosphatidylinositol-4-phosphate 5-kinase-like, putative | 0.0028 | 0.0154 | 0.0253 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0344 | 0.4475 | 0.4465 |
Schistosoma mansoni | smad | 0.0025 | 0.0125 | 0.0107 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0125 | 0.0107 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0056 | 0.0545 | 0.0528 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.005 | 0.0458 | 0.0916 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0156 | 0.1908 | 0.2824 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0085 | 0.0936 | 1 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0039 | 0.031 | 0.3027 |
Loa Loa (eye worm) | FYVE finger-containing phosphoinositide kinase | 0.0028 | 0.0154 | 0.0199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0449 | 0.0644 |
Brugia malayi | Pip kinase protein 1 | 0.0028 | 0.0154 | 0.0199 |
Toxoplasma gondii | phosphatidylinositol-4-phosphate 5-Kinase | 0.0028 | 0.0154 | 0.0285 |
Plasmodium falciparum | phosphatidylinositol-4-phosphate 5-kinase | 0.0028 | 0.0154 | 0.1293 |
Onchocerca volvulus | 0.0507 | 0.6709 | 1 | |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0446 | 0.5875 | 1 |
Trichomonas vaginalis | phosphatidylinositol-4-phosphate 5-kinase type II, putative | 0.0028 | 0.0154 | 0.0204 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0094 | 0.1064 | 0.2239 |
Loa Loa (eye worm) | Smad1 | 0.0025 | 0.0125 | 0.0148 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0111 | 0.0138 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0068 | 0.0708 | 0.0691 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.0936 | 0.092 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0029 | 0.0177 | 0.1728 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0025 | 0.0125 | 0.0148 |
Loa Loa (eye worm) | FYVE zinc finger family protein | 0.0028 | 0.0154 | 0.0199 |
Onchocerca volvulus | Huntingtin homolog | 0.0133 | 0.1592 | 0.2324 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0038 | 0.002 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0125 | 0.0148 |
Echinococcus multilocularis | Phosphatidylinositol 4 phosphate 5 kinase type 1 | 0.0028 | 0.0154 | 0.0137 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0156 | 0.1908 | 0.2824 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0049 | 0.0449 | 0.0644 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0039 | 0.031 | 0.0572 |
Echinococcus granulosus | phosphatidylinositol phosphate 5 kinase type III | 0.0028 | 0.0154 | 0.0137 |
Trichomonas vaginalis | helicase, putative | 0.0049 | 0.0449 | 0.0644 |
Onchocerca volvulus | 0.0047 | 0.0425 | 0.0574 | |
Brugia malayi | hypothetical protein | 0.0232 | 0.2955 | 0.4996 |
Leishmania major | DNA polymerase kappa, putative | 0.0133 | 0.1596 | 0.3402 |
Loa Loa (eye worm) | pip kinase 2 | 0.0344 | 0.4475 | 0.7601 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0039 | 0.031 | 0.0593 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0148 | 0.1805 | 0.3858 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0039 | 0.031 | 0.0593 |
Echinococcus granulosus | Smad4 | 0.0025 | 0.0125 | 0.0107 |
Giardia lamblia | Hypothetical protein | 0.0028 | 0.0154 | 0.0745 |
Leishmania major | DNA polymerase kappa, putative | 0.0039 | 0.031 | 0.0593 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0049 | 0.0449 | 0.0644 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Onchocerca volvulus | 0.0068 | 0.0708 | 0.0997 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.005 | 0.0458 | 0.0916 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0097 | 0.1101 | 0.2031 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0049 | 0.0449 | 0.0644 |
Giardia lamblia | Phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0154 | 0.0745 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0089 | 0.0106 |
Echinococcus granulosus | dna polymerase eta | 0.0183 | 0.2285 | 0.2271 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.007 | 0.0353 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0125 | 0.0148 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0156 | 0.1908 | 0.4082 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0449 | 0.0644 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0156 | 0.1908 | 0.4082 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0111 | 0.0093 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.005 | 0.0458 | 0.0916 |
Onchocerca volvulus | 0.0217 | 0.274 | 0.4047 | |
Mycobacterium ulcerans | DNA polymerase IV | 0.0156 | 0.1908 | 0.8184 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0154 | 0.0253 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0056 | 0.0537 | 0.052 |
Schistosoma mansoni | myst-related protein | 0.0026 | 0.0127 | 0.0109 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0068 | 0.0708 | 0.0691 |
Brugia malayi | polk-prov protein | 0.0069 | 0.0724 | 0.1175 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -9 % | DNDI: Inhibition of Human African Trypanosomiasis, SBRI 427, in vitro at 2 ug.mL-1 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.