Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | polo-like kinase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0043 | 0.0497 | 0.075 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0043 | 0.0497 | 0.1031 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0043 | 0.0497 | 0.075 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.002 | 0.0029 | 0.0061 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0029 | 0.0061 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0043 | 0.0497 | 0.075 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0043 | 0.0497 | 0.1031 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.002 | 0.0029 | 0.0044 |
Schistosoma mansoni | thyroid hormone receptor | 0.0043 | 0.0497 | 0.075 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.0269 | 0.136 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1238 | 0.1867 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.008 | 0.012 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.1238 | 0.1238 |
Schistosoma mansoni | thyroid hormone receptor | 0.0043 | 0.0497 | 0.075 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.002 | 0.0029 | 0.0044 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.375 | 0.5656 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0023 | 0.008 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0953 | 0.1437 |
Brugia malayi | nuclear receptor RXR | 0.0023 | 0.008 | 0.0165 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0056 | 0.0784 | 0.2441 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0114 | 0.198 | 0.4103 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0078 | 0.1238 | 0.1238 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0023 | 0.0096 | 0.0144 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0354 | 0.0535 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.002 | 0.0029 | 0.0044 |
Schistosoma mansoni | lamin | 0.0083 | 0.1333 | 0.2011 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0032 | 0.0269 | 0.0406 |
Brugia malayi | nuclear hormone receptor | 0.0043 | 0.0497 | 0.1031 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0114 | 0.198 | 0.9496 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0497 | 0.075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0043 | 0.0497 | 0.075 |
Echinococcus granulosus | snurportin 1 | 0.0338 | 0.663 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0251 | 0.4825 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0043 | 0.0497 | 0.075 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.1238 | 0.6253 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.008 | 0.012 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0023 | 0.0096 | 0.0773 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.1238 | 0.2565 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0078 | 0.1238 | 0.1867 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0043 | 0.0497 | 0.075 |
Entamoeba histolytica | hypothetical protein | 0.0026 | 0.0145 | 0.0732 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.004 | 0.0443 | 0.0668 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0043 | 0.0497 | 0.075 |
Echinococcus granulosus | FTZ F1 alpha | 0.0043 | 0.0497 | 0.075 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.2083 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0078 | 0.1238 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0953 | 0.1437 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.1238 | 0.1867 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0044 | 0.0534 | 0.0805 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0043 | 0.0497 | 0.1031 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0411 | 0.062 |
Onchocerca volvulus | 0.0047 | 0.0585 | 0.2704 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0497 | 0.075 |
Echinococcus multilocularis | tar DNA binding protein | 0.0199 | 0.375 | 0.5656 |
Schistosoma mansoni | intermediate filament proteins | 0.0083 | 0.1333 | 0.2011 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.375 | 0.5656 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0114 | 0.198 | 0.6164 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0043 | 0.0497 | 0.075 |
Loa Loa (eye worm) | intermediate filament protein | 0.0083 | 0.1333 | 0.2011 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0497 | 0.075 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0056 | 0.0784 | 0.2441 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.327 | 0.4932 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0114 | 0.198 | 0.2985 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0953 | 0.1437 |
Echinococcus granulosus | importin subunit beta 1 | 0.0032 | 0.0269 | 0.0406 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0078 | 0.1238 | 0.6253 |
Mycobacterium ulcerans | hypothetical protein | 0.0078 | 0.1238 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0023 | 0.008 | 0.012 |
Brugia malayi | Muscleblind-like protein | 0.0164 | 0.3018 | 0.6255 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0096 | 0.0483 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0023 | 0.0096 | 0.0773 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0114 | 0.198 | 0.6164 |
Schistosoma mansoni | nuclear receptor | 0.002 | 0.0029 | 0.0044 |
Giardia lamblia | Kinase, PLK | 0.0114 | 0.198 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0043 | 0.0497 | 0.075 |
Leishmania major | GTP-binding protein, putative | 0.0023 | 0.0096 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0497 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Mycobacterium ulcerans | lipase LipD | 0.0078 | 0.1238 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0354 | 0.0535 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0078 | 0.1238 | 0.1238 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0043 | 0.0497 | 0.075 |
Onchocerca volvulus | 0.0078 | 0.1238 | 0.5884 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0043 | 0.0497 | 0.1031 |
Echinococcus multilocularis | GPCR, family 2 | 0.0065 | 0.0953 | 0.1437 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.1238 | 0.1238 |
Echinococcus multilocularis | lamin | 0.0083 | 0.1333 | 0.2011 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | hypothetical protein | 0.0338 | 0.663 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.1238 | 0.3854 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0354 | 0.0735 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.2083 | 0.3142 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0164 | 0.3018 | 0.4551 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0065 | 0.0953 | 0.1975 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0114 | 0.198 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.009 | 0.1481 | 0.307 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0043 | 0.0497 | 0.075 |
Plasmodium vivax | importin-beta 2, putative | 0.0032 | 0.0269 | 0.2175 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.002 | 0.0029 | 0.0044 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.1238 | 0.1238 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.002 | 0.0029 | 0.0044 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0114 | 0.198 | 0.6164 |
Echinococcus granulosus | geminin | 0.0176 | 0.327 | 0.4932 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.002 | 0.0029 | 0.0044 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0078 | 0.1238 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0078 | 0.1238 | 0.6253 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0029 | 0.0061 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0043 | 0.0497 | 0.1031 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0043 | 0.0497 | 0.1031 |
Mycobacterium ulcerans | beta-lactamase | 0.0078 | 0.1238 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | ran | 0.0023 | 0.0096 | 0.0144 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0043 | 0.0497 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0043 | 0.0497 | 0.075 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0043 | 0.0497 | 0.1031 |
Brugia malayi | hypothetical protein | 0.002 | 0.0029 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0953 | 0.1437 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.002 | 0.0029 | 0.0044 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.002 | 0.0029 | 0.0044 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.375 | 0.5656 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0114 | 0.198 | 0.2985 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0145 | 0.0451 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0043 | 0.0497 | 0.1031 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.327 | 0.4932 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0953 | 0.1437 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0411 | 0.062 |
Schistosoma mansoni | nuclear hormone receptor | 0.0043 | 0.0497 | 0.075 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0204 | 0.385 | 0.7979 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0023 | 0.0096 | 0.0144 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0354 | 0.0535 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0953 | 0.1437 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.1238 | 0.3854 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0078 | 0.1238 | 0.1867 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0043 | 0.0497 | 0.1031 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.1238 | 0.2565 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0114 | 0.198 | 0.6164 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0114 | 0.198 | 0.2985 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0114 | 0.198 | 0.6164 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.002 | 0.0029 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0443 | 0.0668 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0043 | 0.0497 | 0.075 |
Echinococcus granulosus | tar DNA binding protein | 0.0199 | 0.375 | 0.5656 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1238 | 0.1867 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.002 | 0.0029 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1238 | 0.1867 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.014 | 0.2509 | 0.52 |
Brugia malayi | steroid hormone receptor | 0.0043 | 0.0497 | 0.1031 |
Brugia malayi | tailless protein | 0.002 | 0.0029 | 0.0061 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0096 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.008 | 0.012 |
Brugia malayi | RNA binding protein | 0.0199 | 0.375 | 0.7773 |
Onchocerca volvulus | 0.0078 | 0.1238 | 0.5884 | |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0029 | 0.0044 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.004 | 0.0443 | 0.0668 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0497 | 0.075 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.1238 | 0.6253 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0114 | 0.198 | 0.6164 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1238 | 0.1867 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0029 | 0.0044 |
Brugia malayi | nuclear receptor RXR | 0.002 | 0.0029 | 0.0061 |
Onchocerca volvulus | 0.0043 | 0.0497 | 0.2278 | |
Schistosoma mansoni | coup transcription factor | 0.0043 | 0.0497 | 0.075 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0023 | 0.008 | 0.0165 |
Echinococcus granulosus | intermediate filament protein | 0.0083 | 0.1333 | 0.2011 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0043 | 0.0497 | 0.075 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.1238 | 0.3854 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0026 | 0.0145 | 0.0732 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0585 | 0.0882 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0043 | 0.0497 | 0.1031 |
Trypanosoma brucei | polo-like protein kinase | 0.0114 | 0.198 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.3313 | 0.4996 |
Brugia malayi | TAR-binding protein | 0.0199 | 0.375 | 0.7773 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0043 | 0.0497 | 0.075 |
Echinococcus granulosus | GPCR family 2 | 0.0065 | 0.0953 | 0.1437 |
Brugia malayi | Importin beta-1 subunit | 0.0032 | 0.0269 | 0.0558 |
Trichomonas vaginalis | ran, putative | 0.0023 | 0.0096 | 0.0298 |
Echinococcus multilocularis | muscleblind protein | 0.0164 | 0.3018 | 0.4551 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.375 | 0.5656 |
Loa Loa (eye worm) | DR-78 | 0.002 | 0.0029 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0354 | 0.1791 |
Loa Loa (eye worm) | beta-lactamase | 0.0078 | 0.1238 | 0.1867 |
Echinococcus granulosus | lamin | 0.0083 | 0.1333 | 0.2011 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0026 | 0.0145 | 0.0451 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.023 | 0.4382 | 0.6608 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | kinase | 0.0058 | 0.0815 | 0.1229 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.002 | 0.0029 | 0.0061 |
Entamoeba histolytica | Ran family GTPase | 0.0023 | 0.0096 | 0.0483 |
Leishmania major | importin beta-1 subunit, putative | 0.0026 | 0.0145 | 0.0732 |
Trichomonas vaginalis | esterase, putative | 0.0078 | 0.1238 | 0.3854 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0083 | 0.1333 | 0.2011 |
Plasmodium falciparum | importin beta, putative | 0.0032 | 0.0269 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0251 | 0.4825 | 0.7277 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.023 | 0.4382 | 0.6608 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.002 | 0.0029 | 0.0061 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0043 | 0.0497 | 0.075 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0043 | 0.0497 | 0.075 |
Mycobacterium leprae | Probable lipase LipE | 0.0078 | 0.1238 | 0.5 |
Onchocerca volvulus | 0.0083 | 0.1333 | 0.6349 | |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0354 | 0.1791 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0078 | 0.1238 | 0.2565 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0043 | 0.0497 | 0.2278 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0029 | 0.0044 |
Loa Loa (eye worm) | RNA binding protein | 0.0199 | 0.375 | 0.5656 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Brugia malayi | ecdysteroid receptor | 0.0043 | 0.0497 | 0.1031 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0096 | 0.3553 |
Schistosoma mansoni | nuclear receptor | 0.002 | 0.0029 | 0.0044 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0083 | 0.1333 | 0.2763 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0497 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.2509 | 0.3784 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0043 | 0.0497 | 0.075 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0032 | 0.0269 | 0.136 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0043 | 0.0497 | 0.1031 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0043 | 0.0497 | 0.1031 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0204 | 0.385 | 0.7979 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.008 | 0.012 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0043 | 0.0497 | 0.075 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0114 | 0.198 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0029 | 0.0044 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0354 | 0.1791 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.3018 | 0.4551 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.0029 | 0.0061 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0178 | 0.3313 | 0.6866 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.1238 | 0.3854 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0354 | 0.0535 |
Brugia malayi | hypothetical protein | 0.0119 | 0.2083 | 0.4317 |
Onchocerca volvulus | 0.0083 | 0.1333 | 0.6349 | |
Echinococcus granulosus | lamin dm0 | 0.0083 | 0.1333 | 0.2011 |
Brugia malayi | hypothetical protein | 0.023 | 0.4382 | 0.9082 |
Echinococcus multilocularis | snurportin 1 | 0.0338 | 0.663 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0199 | 0.375 | 0.5656 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1302 | 0.1963 |
Echinococcus multilocularis | lamin dm0 | 0.0083 | 0.1333 | 0.2011 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0354 | 0.1791 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0114 | 0.198 | 0.2985 |
Plasmodium vivax | hypothetical protein, conserved | 0.0078 | 0.1238 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.375 | 0.5656 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.385 | 0.5806 |
Brugia malayi | nuclear receptor NHR-67 | 0.002 | 0.0029 | 0.0061 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0023 | 0.008 | 0.012 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0204 | 0.385 | 0.5806 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.002 | 0.0029 | 0.0044 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0043 | 0.0497 | 0.1031 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0251 | 0.4825 | 0.7277 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.002 | 0.0029 | 0.0061 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0078 | 0.1238 | 0.1238 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0114 | 0.198 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0029 | 0.0044 |
Echinococcus granulosus | muscleblind protein | 0.0164 | 0.3018 | 0.4551 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0078 | 0.1238 | 0.1238 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.0029 | 0.0061 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0078 | 0.1238 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.002 | 0.0029 | 0.0044 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0096 | 0.0483 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0078 | 0.1238 | 0.1867 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1238 | 0.1867 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.1238 | 0.3854 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0585 | 0.0882 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.1333 | 0.2011 |
Brugia malayi | hypothetical protein | 0.0023 | 0.008 | 0.0165 |
Schistosoma mansoni | importin beta-1 | 0.0032 | 0.0269 | 0.0406 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0199 | 0.375 | 0.7773 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0096 | 0.0483 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0043 | 0.0497 | 0.075 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0023 | 0.008 | 0.0165 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0199 | 0.375 | 0.5656 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0078 | 0.1238 | 0.1238 |
Schistosoma mansoni | ran | 0.0023 | 0.0096 | 0.0144 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.2083 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0043 | 0.0497 | 0.1031 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0269 | 0.0406 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0065 | 0.0953 | 0.1975 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0953 | 0.1437 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0096 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0497 | 0.075 |
Brugia malayi | beta-lactamase | 0.0078 | 0.1238 | 0.2565 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0065 | 0.0953 | 0.1437 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0032 | 0.0269 | 0.2175 |
Brugia malayi | conserved hypotetical protein | 0.002 | 0.0029 | 0.0061 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0078 | 0.1238 | 0.1238 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.4382 | 0.6608 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0043 | 0.0497 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.008 | 0.012 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0114 | 0.198 | 0.6164 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0096 | 0.0483 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0043 | 0.0497 | 0.1031 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0023 | 0.008 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.3018 | 0.4551 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0043 | 0.0497 | 0.1031 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0585 | 0.1212 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0043 | 0.0497 | 0.075 |
Toxoplasma gondii | ABC1 family protein | 0.0078 | 0.1238 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.002 | 0.0029 | 0.0044 |
Brugia malayi | ecdysone receptor | 0.002 | 0.0029 | 0.0061 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.002 | 0.0029 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0953 | 0.1437 |
Echinococcus multilocularis | geminin | 0.0176 | 0.327 | 0.4932 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0043 | 0.0497 | 0.1031 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Trichomonas vaginalis | importin beta-1, putative | 0.0026 | 0.0145 | 0.0451 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0044 | 0.0534 | 0.1107 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0953 | 0.1437 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0173 | 0.3211 | 1 |
Brugia malayi | hypothetical protein | 0.002 | 0.0029 | 0.0061 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.002 | 0.0029 | 0.0044 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0078 | 0.1238 | 0.1238 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.1238 | 0.1867 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0023 | 0.008 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.2509 | 0.3784 |
Schistosoma mansoni | lamin | 0.0083 | 0.1333 | 0.2011 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.002 | 0.0029 | 0.0044 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0043 | 0.0497 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Echinococcus multilocularis | musashi | 0.0083 | 0.1333 | 0.2011 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0043 | 0.0497 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0029 | 0.0044 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0043 | 0.0497 | 0.075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0043 | 0.0497 | 0.075 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0338 | 0.663 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.2083 | 0.3142 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0043 | 0.0497 | 0.075 |
Onchocerca volvulus | 0.0078 | 0.1238 | 0.5884 | |
Brugia malayi | intermediate filament protein | 0.0083 | 0.1333 | 0.2763 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0114 | 0.198 | 1 |
Brugia malayi | hypothetical protein | 0.0023 | 0.008 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1238 | 0.1867 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.