Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | doublecortin family protein | 0.0024 | 0.0286 | 0.0286 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.1041 | 0.0929 |
Trypanosoma brucei | unspecified product | 0.0024 | 0.027 | 0.0534 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0036 | 0.0659 | 0.0542 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0927 | 0.0927 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.1041 | 0.2203 |
Loa Loa (eye worm) | glutaminase | 0.0333 | 1 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0262 | 0.7755 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0024 | 0.027 | 0.0192 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0818 | 0.1721 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0818 | 0.156 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0024 | 0.027 | 0.1046 |
Schistosoma mansoni | loxhd1 | 0.0024 | 0.0286 | 0.0286 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0123 | 0.0026 |
Schistosoma mansoni | DNA polymerase eta | 0.0055 | 0.1246 | 0.1246 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0063 | 0.1526 | 0.3518 |
Trypanosoma brucei | unspecified product | 0.0016 | 0.0041 | 0.0038 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0333 | 0.0333 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0153 | 0.4338 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0024 | 0.027 | 0.0622 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0063 | 0.1526 | 0.3255 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.1041 | 0.2203 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0042 | 0.0849 | 0.1958 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0024 | 0.027 | 0.0534 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0041 | 0.0818 | 0.0911 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0036 | 0.0659 | 0.1209 |
Loa Loa (eye worm) | RNA binding protein | 0.0046 | 0.099 | 0.099 |
Echinococcus granulosus | tar DNA binding protein | 0.0046 | 0.099 | 0.2282 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0256 | 0.0256 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0036 | 0.0659 | 0.1209 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0818 | 0.0818 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0659 | 0.0659 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0286 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0111 | 0.0111 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.0818 | 0.0818 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0597 | 0.0621 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0024 | 0.027 | 0.0149 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0024 | 0.027 | 0.0149 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0067 | 0.1645 | 0.3792 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.3213 | 0.3213 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0161 | 0.0371 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0195 | 0.0195 |
Schistosoma mansoni | lipoxygenase | 0.0067 | 0.1645 | 0.1645 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0041 | 0.0818 | 0.0911 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0041 | 0.0038 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0041 | 0.0818 | 0.0911 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0024 | 0.0286 | 0.0659 |
Echinococcus multilocularis | tar DNA binding protein | 0.0046 | 0.099 | 0.2282 |
Schistosoma mansoni | tar DNA-binding protein | 0.0046 | 0.099 | 0.099 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0818 | 0.0911 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0123 | 0.3397 | 0.7308 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0063 | 0.1526 | 0.142 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0063 | 0.1526 | 0.1526 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.0818 | 0.1886 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0163 | 0.4641 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1246 | 0.1246 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0818 | 0.1721 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.1452 | 0.3347 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.0818 | 0.156 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0024 | 0.0286 | 0.0385 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0818 | 0.0911 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.4338 | 0.4338 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.0818 | 0.0818 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0048 | 0.1041 | 0.6539 |
Brugia malayi | chromobox protein homolog 3 | 0.0044 | 0.0927 | 0.0927 |
Brugia malayi | Doublecortin family protein | 0.0024 | 0.0286 | 0.0286 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0818 | 0.0704 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0024 | 0.027 | 0.027 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Echinococcus granulosus | chromobox protein 1 | 0.0079 | 0.2022 | 0.466 |
Onchocerca volvulus | 0.0041 | 0.0818 | 0.7051 | |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0038 | 0.0736 | 0.1543 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0763 | 0.0763 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0123 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0818 | 0.0818 |
Mycobacterium ulcerans | lipase LipD | 0.0041 | 0.0818 | 0.0704 |
Onchocerca volvulus | 0.0035 | 0.0625 | 0.4499 | |
Mycobacterium ulcerans | DNA polymerase IV | 0.0024 | 0.027 | 0.0149 |
Schistosoma mansoni | tar DNA-binding protein | 0.0046 | 0.099 | 0.099 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0818 | 0.0818 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0123 | 0.3397 | 0.7832 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0018 | 0.0111 | 0.0191 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0048 | 0.1041 | 0.0929 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0046 | 0.099 | 0.099 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0024 | 0.027 | 0.0192 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0111 | 0.0111 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0048 | 0.1041 | 0.0929 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.008 | 0.008 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0659 | 0.0659 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0067 | 0.1645 | 0.3792 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0099 | 0.0099 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0063 | 0.1526 | 0.3518 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0818 | 0.0818 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0063 | 0.1526 | 0.142 |
Mycobacterium ulcerans | glutaminase | 0.0333 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0055 | 0.1246 | 0.2647 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0766 | 0.0766 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0927 | 0.0814 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.3397 | 0.3315 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0818 | 0.0704 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0042 | 0.0849 | 0.1958 |
Schistosoma mansoni | chromobox protein | 0.0079 | 0.2022 | 0.2022 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.1041 | 0.1041 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0024 | 0.027 | 0.0622 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0818 | 0.0704 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0041 | 0.0818 | 0.0911 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0048 | 0.1041 | 0.0929 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0024 | 0.0286 | 0.0659 |
Brugia malayi | RNA binding protein | 0.0046 | 0.099 | 0.099 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0041 | 0.0038 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0818 | 0.0911 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0625 | 0.0625 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0256 | 0.0591 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0286 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0818 | 0.0818 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0063 | 0.1526 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0048 | 0.1041 | 0.1202 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.1041 | 0.6539 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0024 | 0.0286 | 0.0385 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.4338 | 0.4338 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.0849 | 0.0849 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0024 | 0.027 | 0.0622 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0123 | 0.0284 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0048 | 0.1041 | 0.1202 |
Brugia malayi | Heterochromatin protein 1 | 0.0079 | 0.2022 | 0.2022 |
Leishmania major | hypothetical protein, conserved | 0.0018 | 0.0111 | 0.0191 |
Brugia malayi | Bromodomain containing protein | 0.0077 | 0.1944 | 0.1944 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0063 | 0.1526 | 0.142 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0659 | 0.0659 |
Echinococcus multilocularis | muscleblind protein | 0.0153 | 0.4338 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.1041 | 0.0929 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0286 | 0.0286 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0123 | 0.0217 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0597 | 0.0621 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0038 | 0.0736 | 0.1378 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.0163 | 0.4641 | 1 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0063 | 0.1526 | 0.142 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0042 | 0.0849 | 0.1958 |
Schistosoma mansoni | tar DNA-binding protein | 0.0046 | 0.099 | 0.099 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0927 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1041 | 0.1041 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0687 | 0.1584 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0079 | 0.2022 | 0.2022 |
Leishmania major | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.0818 | 0.0818 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0123 | 0.3397 | 0.7832 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0024 | 0.027 | 0.027 |
Onchocerca volvulus | 0.0041 | 0.0818 | 0.7051 | |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0286 | 0.0286 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0024 | 0.027 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.008 | 0.008 |
Echinococcus granulosus | muscleblind protein | 0.0153 | 0.4338 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0041 | 0.0818 | 0.0911 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.008 | 0.008 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.1041 | 0.2203 |
Echinococcus multilocularis | dna polymerase eta | 0.0055 | 0.1246 | 0.2871 |
Schistosoma mansoni | polycystin 1-related | 0.0024 | 0.0286 | 0.0286 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0818 | 0.1721 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.0849 | 0.0849 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.0163 | 0.4641 | 1 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.0163 | 0.4641 | 0.4641 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.0163 | 0.4641 | 0.4574 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0659 | 0.0659 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0687 | 0.1584 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0024 | 0.0286 | 0.0659 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.1041 | 0.0929 |
Loa Loa (eye worm) | inward rectifying k channel family protein 1 | 0.005 | 0.1097 | 0.1097 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0024 | 0.027 | 0.0534 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0055 | 0.1246 | 0.2647 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.1041 | 0.1041 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0041 | 0.0818 | 0.0704 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0018 | 0.0111 | 0.0191 |
Onchocerca volvulus | 0.0041 | 0.0818 | 0.7051 | |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0024 | 0.0286 | 0.0659 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.0163 | 0.4641 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0024 | 0.0286 | 0.0286 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0024 | 0.0286 | 0.0659 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.3213 | 0.3213 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.0163 | 0.4641 | 1 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0063 | 0.1526 | 0.142 |
Echinococcus multilocularis | RUN | 0.0024 | 0.0286 | 0.0659 |
Mycobacterium ulcerans | beta-lactamase | 0.0041 | 0.0818 | 0.0704 |
Brugia malayi | Muscleblind-like protein | 0.0153 | 0.4338 | 0.4338 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.0849 | 0.0849 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0123 | 0.3397 | 0.3397 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0036 | 0.0659 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1097 | 0.1097 |
Trichomonas vaginalis | esterase, putative | 0.0041 | 0.0818 | 0.0704 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.1041 | 0.0582 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0286 | 0.0286 |
Loa Loa (eye worm) | glutaminase 2 | 0.0333 | 1 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0079 | 0.2022 | 0.466 |
Brugia malayi | TAR-binding protein | 0.0046 | 0.099 | 0.099 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.1807 | 0.1807 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0163 | 0.4641 | 1 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0063 | 0.1526 | 0.3518 |
Loa Loa (eye worm) | TAR-binding protein | 0.0046 | 0.099 | 0.099 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0123 | 0.0026 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.0163 | 0.4641 | 1 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0163 | 0.4641 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0123 | 0.0123 |
Trichomonas vaginalis | glutaminase, putative | 0.0333 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1041 | 0.1041 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.3397 | 0.3315 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0163 | 0.4641 | 0.4641 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1041 | 0.1041 |
Schistosoma mansoni | lipoxygenase | 0.0024 | 0.0286 | 0.0286 |
Schistosoma mansoni | tar DNA-binding protein | 0.0046 | 0.099 | 0.099 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0123 | 0.3397 | 0.3315 |
Toxoplasma gondii | hypothetical protein | 0.005 | 0.1097 | 0.2177 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.1452 | 0.3347 |
Trichomonas vaginalis | chromobox protein, putative | 0.0079 | 0.2022 | 0.1922 |
Schistosoma mansoni | rab6-interacting | 0.0024 | 0.0286 | 0.0286 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0017 | 0.008 | 0.0184 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0123 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0659 | 0.0659 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0063 | 0.1526 | 0.3518 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0017 | 0.008 | 0.0184 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.3213 | 0.3213 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0024 | 0.027 | 0.027 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0818 | 0.0704 |
Schistosoma mansoni | chromobox protein | 0.0079 | 0.2022 | 0.2022 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0818 | 0.0818 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0055 | 0.1246 | 0.1246 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.0163 | 0.4641 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0597 | 0.0621 |
Echinococcus multilocularis | dna polymerase kappa | 0.0024 | 0.027 | 0.0622 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.008 | 0.0184 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0519 | 0.0401 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0041 | 0.0038 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0123 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0161 | 0.0161 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.0597 | 0.0621 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0123 | 0.0123 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0818 | 0.0704 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0036 | 0.0659 | 0.0702 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.008 | 0.0184 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0123 | 0.3397 | 0.3397 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0927 | 0.8496 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0163 | 0.4641 | 0.4641 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0161 | 0.0371 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.1567 | 0.1567 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0818 | 0.0818 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0042 | 0.0849 | 0.0849 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0123 | 0.0123 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0042 | 0.0849 | 0.1958 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0818 | 0.0704 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.1041 | 0.0582 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0024 | 0.027 | 0.0534 |
Trichomonas vaginalis | chromobox protein, putative | 0.0048 | 0.1033 | 0.0921 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0024 | 0.027 | 0.0534 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0818 | 0.1721 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0123 | 0.0217 |
Trichomonas vaginalis | chromobox protein, putative | 0.0079 | 0.2022 | 0.1922 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0024 | 0.0286 | 0.0659 |
Leishmania major | dihydroorotate dehydrogenase | 0.0163 | 0.4641 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0256 | 0.0591 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.0163 | 0.4641 | 0.5919 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0818 | 0.0818 |
Giardia lamblia | DINP protein human, muc B family | 0.0024 | 0.027 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1097 | 0.1097 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0024 | 0.027 | 0.027 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0041 | 0.0818 | 0.0911 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.1041 | 0.1041 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.1041 | 0.6539 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0018 | 0.0111 | 0.0191 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0195 | 0.0195 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0048 | 0.1033 | 0.9901 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0048 | 0.1041 | 0.0929 |
Mycobacterium ulcerans | hypothetical protein | 0.0048 | 0.1041 | 0.0929 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0123 | 0.0026 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0123 | 0.0217 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0063 | 0.1526 | 0.142 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1097 | 0.1097 |
Onchocerca volvulus | 0.0048 | 0.1041 | 1 | |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.0818 | 0.1886 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0818 | 0.0818 |
Echinococcus granulosus | chromobox protein 1 | 0.0079 | 0.2022 | 0.466 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0519 | 0.0401 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0903 | 0.0903 |
Brugia malayi | beta-lactamase | 0.0041 | 0.0818 | 0.0818 |
Schistosoma mansoni | glutaminase | 0.0333 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0055 | 0.1246 | 0.2647 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0023 | 0.0023 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0818 | 0.0818 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.008 | 0.008 |
Echinococcus granulosus | dna polymerase eta | 0.0055 | 0.1246 | 0.2871 |
Trichomonas vaginalis | chromobox protein, putative | 0.0048 | 0.1033 | 0.0921 |
Echinococcus granulosus | RUN | 0.0024 | 0.0286 | 0.0659 |
Echinococcus multilocularis | chromobox protein 1 | 0.0079 | 0.2022 | 0.466 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0123 | 0.3397 | 0.429 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0046 | 0.099 | 0.099 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0024 | 0.027 | 0.0534 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0842 | 0.0842 |
Trypanosoma brucei | unspecified product | 0.0016 | 0.0041 | 0.0038 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0041 | 0.0818 | 0.0911 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.0023 | 0.0023 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0123 | 0.0123 |
Leishmania major | DNA polymerase eta, putative | 0.0038 | 0.0736 | 0.1543 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.008 | 0.008 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0123 | 0.3397 | 0.7255 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0042 | 0.0849 | 0.0849 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0041 | 0.0818 | 0.0704 |
Schistosoma mansoni | tar DNA-binding protein | 0.0046 | 0.099 | 0.099 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 68.6 % | Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level at 50 uM after 4 hrs by G-LISA relative to control | ChEMBL. | 19527032 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.