Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.171 | 0.3769 |
Brugia malayi | TAR-binding protein | 0.0074 | 0.2676 | 0.724 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0508 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0785 | 0.0869 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0785 | 0.0869 |
Loa Loa (eye worm) | TAR-binding protein | 0.0074 | 0.2676 | 0.6801 |
Onchocerca volvulus | 0.0035 | 0.0785 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.7123 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0508 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0074 | 0.2676 | 0.2984 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0785 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0785 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.2676 | 0.2984 |
Echinococcus multilocularis | tar DNA binding protein | 0.0074 | 0.2676 | 0.2984 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0785 | 0.0869 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.3696 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0785 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0785 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0876 | 0.0144 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0785 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.3696 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.3696 | 0.4594 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.3696 | 0.4594 |
Echinococcus multilocularis | geminin | 0.0165 | 0.7123 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.3696 | 0.4594 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0074 | 0.2676 | 0.6801 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0785 | 0.0869 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0785 | 0.0869 |
Brugia malayi | RNA binding protein | 0.0074 | 0.2676 | 0.724 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0876 | 0.1154 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.3696 | 0.4594 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0785 | 0.5 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0785 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0785 | 0.0869 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0785 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.171 | 0.4625 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0785 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.2676 | 0.2984 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0785 | 0.2123 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0785 | 0.0869 |
Loa Loa (eye worm) | RNA binding protein | 0.0074 | 0.2676 | 0.6801 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0508 | 0.1374 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.171 | 0.3769 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0785 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.2676 | 0.2984 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0785 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0785 | 1 |
Onchocerca volvulus | 0.0035 | 0.0785 | 0.5 | |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0785 | 0.5 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0785 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0785 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0876 | 0.237 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.3696 | 0.4594 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.171 | 0.4625 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.7123 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.3696 | 0.4594 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0074 | 0.2676 | 0.724 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.2676 | 0.2984 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0785 | 0.2123 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.2676 | 0.2984 |
Echinococcus granulosus | geminin | 0.0165 | 0.7123 | 1 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0785 | 0.2123 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0785 | 0.5 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0785 | 0.5 |
Onchocerca volvulus | 0.0035 | 0.0785 | 0.5 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0785 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0785 | 0.2123 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0785 | 0.0869 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.3696 | 0.4594 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0785 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.