Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0737 | 0.5 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0737 | 0.5 | 0.5 |
Echinococcus multilocularis | peroxidasin | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0737 | 0.5 | 0.5 |
Onchocerca volvulus | Dual oxidase homolog | 0.0737 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0737 | 0.5 | 0.5 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0737 | 0.5 | 0.5 |
Onchocerca volvulus | Peroxidase homolog | 0.0737 | 0.5 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0737 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0737 | 0.5 | 0.5 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0737 | 0.5 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0737 | 0.5 | 0.5 |
Brugia malayi | Peroxidasin | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0737 | 0.5 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Onchocerca volvulus | Peroxidase homolog | 0.0737 | 0.5 | 0.5 |
Brugia malayi | Blistered cuticle protein 3 | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0737 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0737 | 0.5 | 0.5 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0737 | 0.5 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0737 | 0.5 | 0.5 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0737 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0737 | 0.5 | 0.5 |
Echinococcus granulosus | peroxidasin | 0.0737 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 19 % | Agonist activity at human CB2 receptor expressed in CHO cells at 10 uM by [35]GTPgammaS binding assay relative to basal level | ChEMBL. | 19477133 |
Activity (binding) | = 100 % | Agonist activity at rat cerebellar membrane CB1 receptor at 10 uM by [35]GTPgammaS binding assay relative to basal level | ChEMBL. | 19477133 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.