Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | importin subunit beta 1 | 0.003 | 0.0497 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.3211 | 0.3655 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0061 | 0.1157 | 0.1413 |
Toxoplasma gondii | mitochondrial import inner membrane translocase subunit TIM10, putative | 0.0051 | 0.0937 | 0.4296 |
Echinococcus granulosus | ferritin | 0.0009 | 0.0054 | 0.0057 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0092 | 0.18 | 0.8902 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.1157 | 0.1413 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0163 | 0.2193 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0106 | 0.2099 | 0.2556 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0054 | 0.0066 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0259 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0017 | 0.0219 | 0.0566 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0102 | 0.2015 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0954 | 0.1081 |
Schistosoma mansoni | tar DNA-binding protein | 0.0196 | 0.3977 | 0.4855 |
Loa Loa (eye worm) | histone methyltransferase | 0.0011 | 0.0097 | 0.0102 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0014 | 0.0163 | 0.0177 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0063 | 0.0063 |
Treponema pallidum | NADH oxidase | 0.0014 | 0.0163 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0397 | 0.819 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0102 | 0.2015 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.0085 | 0.1654 | 0.1879 |
Schistosoma mansoni | importin beta-1 | 0.003 | 0.0497 | 0.0607 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0063 | 0.0068 |
Brugia malayi | TAR-binding protein | 0.0196 | 0.3977 | 0.4529 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.1157 | 0.1312 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0487 | 0.0594 |
Loa Loa (eye worm) | RNA binding protein | 0.0196 | 0.3977 | 0.4529 |
Schistosoma mansoni | tar DNA-binding protein | 0.0196 | 0.3977 | 0.4855 |
Echinococcus granulosus | muscleblind protein | 0.0159 | 0.3211 | 0.3915 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0041 | 0.0727 | 0.0879 |
Brugia malayi | Pre-SET motif family protein | 0.0425 | 0.8772 | 1 |
Schistosoma mansoni | hypothetical protein | 0.032 | 0.657 | 0.8021 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0063 | 0.0077 |
Plasmodium falciparum | mitochondrial import inner membrane translocase subunit TIM10, putative | 0.0051 | 0.0937 | 1 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0054 | 0.0066 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0054 | 0.0066 |
Schistosoma mansoni | tar DNA-binding protein | 0.0196 | 0.3977 | 0.4855 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0106 | 0.2099 | 0.2563 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0007 | 0.0007 | 0.0009 |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.1157 | 0.1312 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0009 | 0.0061 | 0.0066 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0378 | 0.5238 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.3799 | 0.4326 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0159 | 0.3211 | 0.3915 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0014 | 0.0163 | 0.0554 |
Plasmodium vivax | mitochondrial import inner membrane translocase subunit TIM10, putative | 0.0051 | 0.0937 | 0.779 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0259 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0063 | 0.0063 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0652 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0954 | 0.1081 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0054 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0611 | 0.0689 |
Echinococcus multilocularis | tar DNA binding protein | 0.0196 | 0.3977 | 0.4851 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0213 | 0.0234 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0378 | 0.0377 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.032 | 0.657 | 0.7487 |
Echinococcus multilocularis | snurportin 1 | 0.032 | 0.657 | 0.802 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0054 | 0.0066 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0014 | 0.0163 | 0.019 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0163 | 0.2193 |
Plasmodium vivax | thioredoxin reductase, putative | 0.004 | 0.0716 | 0.556 |
Trichomonas vaginalis | ferritin, putative | 0.0009 | 0.0054 | 0.0052 |
Echinococcus granulosus | expressed protein | 0.0051 | 0.0937 | 0.1137 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | transport to inner mitochondrial membrane family member | 0.0051 | 0.0937 | 0.1061 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0652 | 0.0789 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0331 | 1 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0009 | 0.0061 | 0.0066 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0213 | 0.0251 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0196 | 0.3977 | 0.4529 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0106 | 0.2099 | 0.2563 |
Brugia malayi | Importin beta-1 subunit | 0.003 | 0.0497 | 0.0559 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0063 | 0.0063 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0331 | 0.305 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0259 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0163 | 0.2193 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0022 | 0.0331 | 0.0396 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.3211 | 0.3655 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0487 | 0.0586 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0767 |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.1157 | 1 |
Schistosoma mansoni | mitochondrial import inner membrane translocase subunit tim10 | 0.0051 | 0.0937 | 0.1145 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0652 | 0.0736 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0213 | 0.026 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0213 | 0.0251 |
Onchocerca volvulus | 0.0028 | 0.0454 | 0.0447 | |
Mycobacterium tuberculosis | Probable reductase | 0.0092 | 0.18 | 0.8902 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0014 | 0.0163 | 0.5 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0425 | 0.8772 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0213 | 0.0251 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0213 | 0.026 |
Echinococcus multilocularis | expressed protein | 0.0051 | 0.0937 | 0.1137 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0954 | 0.1081 |
Trypanosoma brucei | trypanothione reductase | 0.004 | 0.0716 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0102 | 0.2015 | 1 |
Schistosoma mansoni | ras GTP exchange factor | 0.0007 | 0.0007 | 0.0009 |
Trichomonas vaginalis | guanine nucleotide exchange factor, putative | 0.0007 | 0.0007 | 0.0006 |
Loa Loa (eye worm) | TAR-binding protein | 0.0196 | 0.3977 | 0.4529 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0009 | 0.0061 | 0.0075 |
Schistosoma mansoni | tar DNA-binding protein | 0.0196 | 0.3977 | 0.4855 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0063 | 0.0068 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.0219 | 0.0259 |
Toxoplasma gondii | TIM10 family protein, putative | 0.0051 | 0.0937 | 0.4296 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0063 | 0.0068 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0242 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0652 | 0.0797 |
Plasmodium falciparum | thioredoxin reductase | 0.004 | 0.0716 | 0.7137 |
Loa Loa (eye worm) | glutathione reductase | 0.004 | 0.0716 | 0.0808 |
Plasmodium vivax | glutathione reductase, putative | 0.004 | 0.0716 | 0.556 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0611 | 0.0689 |
Schistosoma mansoni | camp-dependent rap1 guanine-nucleotide exchange factor | 0.0006 | 0 | 0.0001 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0014 | 0.0163 | 0.019 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0014 | 0.0163 | 0.2193 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0331 | 0.037 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.0106 | 0.2099 | 0.2556 |
Echinococcus granulosus | snurportin 1 | 0.032 | 0.657 | 0.802 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0454 | 0.0554 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0071 | 0.1356 | 0.1656 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0017 | 0.0219 | 0.2988 |
Trichomonas vaginalis | ran, putative | 0.0022 | 0.0331 | 0.033 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0219 | 0.1018 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0652 | 1 |
Schistosoma mansoni | ran | 0.0022 | 0.0331 | 0.0404 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0063 | 0.0063 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0041 | 0.0727 | 0.0879 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0022 | 0.0331 | 0.1319 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0063 | 0.0063 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0061 | 0.0066 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0092 | 0.18 | 0.8902 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0071 | 0.1356 | 0.1656 |
Brugia malayi | RNA binding protein | 0.0196 | 0.3977 | 0.4529 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0213 | 0.026 |
Brugia malayi | Mitochondrial import inner membrane translocase subunit TIM10 | 0.0051 | 0.0937 | 0.1061 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0213 | 0.0251 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0059 | 0.1097 | 0.1332 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0219 | 0.1018 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0259 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0054 | 0.0066 |
Echinococcus multilocularis | muscleblind protein | 0.0159 | 0.3211 | 0.3915 |
Loa Loa (eye worm) | thioredoxin reductase | 0.004 | 0.0716 | 0.0808 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0022 | 0.0331 | 0.0396 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0454 | 0.0509 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0063 | 0.0068 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0017 | 0.0219 | 0.0727 |
Echinococcus multilocularis | ferritin | 0.0009 | 0.0054 | 0.0057 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0063 | 0.0068 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0092 | 0.18 | 0.8902 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0267 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0014 | 0.0163 | 1 |
Trichomonas vaginalis | ras GTP exchange factor, son of sevenless, putative | 0.0007 | 0.0007 | 0.0006 |
Brugia malayi | Melibiase family protein | 0.0071 | 0.1356 | 0.1539 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0063 | 0.0063 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0106 | 0.2099 | 0.2563 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0007 | 0.0009 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0071 | 0.1356 | 0.1355 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0242 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0063 | 0.0063 |
Entamoeba histolytica | Ran family GTPase | 0.0022 | 0.0331 | 0.5022 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0009 | 0.0063 | 0.0056 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0487 | 0.0594 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0497 | 0.6047 |
Leishmania major | GTP-binding protein, putative | 0.0022 | 0.0331 | 0.305 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.1155 | 0.1411 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0106 | 0.2099 | 0.2556 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0007 | 0.0009 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0196 | 0.3977 | 0.4529 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0611 | 0.0746 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.1157 | 0.1413 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0331 | 0.4575 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0331 | 0.2177 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0061 | 0.0066 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0063 | 0.0077 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0163 | 0.2193 |
Plasmodium falciparum | importin beta, putative | 0.003 | 0.0497 | 0.4316 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0007 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0497 | 0.0559 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0163 | 0.2193 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0017 | 0.0219 | 0.0841 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0014 | 0.0163 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0097 | 0.011 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0213 | 0.026 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0014 | 0.0163 | 0.0161 |
Trichomonas vaginalis | ras GTP exchange factor, putative | 0.0007 | 0.0007 | 0.0006 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0063 | 0.0068 |
Leishmania major | trypanothione reductase | 0.004 | 0.0716 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0014 | 0.0163 | 0.2193 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0652 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0487 | 0.0586 |
Schistosoma mansoni | hypothetical protein | 0.0397 | 0.819 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0397 | 0.819 | 1 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0063 | 0.0068 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0213 | 0.0234 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0767 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.1023 | 0.4717 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0054 | 0.0066 |
Echinococcus granulosus | expressed protein | 0.0009 | 0.0054 | 0.0057 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.1157 | 0.1405 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0014 | 0.0163 | 0.049 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0063 | 0.0077 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0092 | 0.18 | 0.8902 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0061 | 0.1157 | 0.1405 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.004 | 0.0716 | 0.3374 |
Brugia malayi | N-terminal motif family protein | 0.0187 | 0.3799 | 0.4326 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0014 | 0.0163 | 0.0198 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0063 | 0.0063 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0054 | 0.0066 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0014 | 0.0163 | 0.049 |
Schistosoma mansoni | tar DNA-binding protein | 0.0196 | 0.3977 | 0.4855 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0014 | 0.0163 | 0.2193 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0061 | 0.1157 | 0.1405 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0014 | 0.0163 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.004 | 0.0716 | 0.3206 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0378 | 0.39 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0378 | 0.5751 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0497 | 0.6047 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0092 | 0.18 | 0.8902 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0063 | 0.0063 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0219 | 0.2988 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0063 | 0.0077 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0331 | 0.037 |
Toxoplasma gondii | melibiase subfamily protein | 0.0106 | 0.2099 | 1 |
Echinococcus multilocularis | expressed protein | 0.0009 | 0.0054 | 0.0057 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.001 | 0.0085 | 0.0088 |
Echinococcus granulosus | tar DNA binding protein | 0.0196 | 0.3977 | 0.4851 |
Schistosoma mansoni | ran | 0.0022 | 0.0331 | 0.0404 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0213 | 0.0251 |
Trichomonas vaginalis | ras GTP exchange factor, putative | 0.0007 | 0.0007 | 0.0006 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0014 | 0.0163 | 0.2193 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0213 | 0.0234 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0063 | 0.0068 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0652 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.1157 | 0.1413 |
Brugia malayi | Thioredoxin reductase | 0.004 | 0.0716 | 0.0808 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0063 | 0.0068 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0378 | 0.0377 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0187 | 0.3799 | 0.3794 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0063 | 0.0068 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0102 | 0.2015 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0652 | 0.0797 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0061 | 0.1157 | 0.5375 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0213 | 0.0234 |
Onchocerca volvulus | 0.0061 | 0.1157 | 0.1151 | |
Trichomonas vaginalis | set domain proteins, putative | 0.0483 | 1 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0454 | 0.0509 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0014 | 0.0163 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0954 | 0.1081 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0331 | 0.4575 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0106 | 0.2099 | 0.2563 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0092 | 0.18 | 0.8902 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0063 | 0.0077 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.0378 | 0.0377 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0095 | 0.01 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0022 | 0.0331 | 0.1696 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0652 | 0.0789 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0213 | 0.0251 |
Onchocerca volvulus | 0.0009 | 0.0063 | 0.0056 | |
Brugia malayi | glutathione reductase | 0.004 | 0.0716 | 0.0808 |
Echinococcus multilocularis | importin subunit beta 1 | 0.003 | 0.0497 | 0.0599 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0063 | 0.0063 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0015 | 0.0185 | 0.0226 |
Toxoplasma gondii | Alpha-galactosidase | 0.0015 | 0.0185 | 0.06 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0017 | 0.0219 | 0.1018 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0014 | 0.0163 | 0.0161 |
Plasmodium vivax | importin-beta 2, putative | 0.003 | 0.0497 | 0.3362 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0219 | 0.0259 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.001 | 0.0085 | 0.0088 |
Plasmodium falciparum | glutathione reductase | 0.004 | 0.0716 | 0.7137 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.003 | 0.0497 | 0.2133 |
Brugia malayi | Muscleblind-like protein | 0.0159 | 0.3211 | 0.3655 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0097 | 0.011 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.004 | 0.0716 | 1 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0063 | 0.0077 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0014 | 0.0163 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1356 | 0.1539 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -7 % | DNDI: Inhibition of Human African Trypanosomiasis, SBRI 427, in vitro at 2 ug.mL-1 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.