Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1139 | 0.1139 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.1139 | 0.1421 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.1139 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1139 | 0.1139 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.1139 | 0.107 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0293 | 0.0288 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0899 | 0.0828 |
Onchocerca volvulus | 0.0035 | 0.1139 | 0.6627 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0339 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0293 | 0.0293 |
Schistosoma mansoni | jumonji domain containing protein | 0.0127 | 0.532 | 0.7014 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0339 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0023 | 0.0598 | 0.0598 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0127 | 0.532 | 0.532 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1139 | 0.1139 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0339 | 0.0264 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0293 | 0.0293 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.2561 | 1 |
Plasmodium vivax | JmjC domain containing protein | 0.0034 | 0.1087 | 0.9348 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0448 | 0.0496 |
Onchocerca volvulus | 0.0035 | 0.1139 | 0.6627 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0293 | 0.0217 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0034 | 0.1087 | 1 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0034 | 0.1087 | 0.1087 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Echinococcus multilocularis | geminin | 0.0176 | 0.7552 | 0.7552 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.1087 | 0.1018 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.002 | 0.0448 | 0.0448 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0293 | 0.0288 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0054 | 0.1988 | 0.1988 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0077 | 0.0077 |
Schistosoma mansoni | zinc finger protein | 0.0017 | 0.0326 | 0.0334 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0293 | 0.0288 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Brugia malayi | Doublecortin family protein | 0.0019 | 0.0419 | 0.0345 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.101 | 0.094 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0034 | 0.1087 | 0.3403 |
Echinococcus granulosus | zinc finger protein | 0.0024 | 0.0628 | 0.0628 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0069 | 0.267 | 0.267 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0034 | 0.1087 | 0.3403 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0419 | 0.0419 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.0905 | 0.0834 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0034 | 0.1087 | 0.3403 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0066 | 0.2561 | 1 |
Echinococcus granulosus | phd:f box containing protein | 0.0034 | 0.1087 | 0.1087 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.1139 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0419 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1157 | 0.1157 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.119 | 0.1489 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0019 | 0.0416 | 0.0416 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0419 | 0.0345 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 1 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0416 | 0.0453 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1087 | 0.1087 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0339 | 0.035 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.168 | 0.2144 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.1139 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0293 | 0.0293 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.1139 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0339 | 0.0339 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.1139 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.1139 | 0.3636 |
Onchocerca volvulus | 0.0032 | 0.101 | 0.5819 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0339 | 0.0339 |
Brugia malayi | Bromodomain containing protein | 0.0043 | 0.1497 | 0.1431 |
Schistosoma mansoni | bromodomain containing protein | 0.0073 | 0.2852 | 0.3713 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0105 | 0.4333 | 0.4333 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.1087 | 0.1018 |
Schistosoma mansoni | zinc finger protein | 0.0024 | 0.0628 | 0.0736 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.2561 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0105 | 0.4333 | 0.4289 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0339 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.1139 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.119 | 0.119 |
Brugia malayi | jmjC domain containing protein | 0.0131 | 0.5501 | 0.5466 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0339 | 0.0339 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0034 | 0.1087 | 0.3564 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0019 | 0.0419 | 0.1006 |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0339 | 0.0339 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.1139 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.1139 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.7552 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0131 | 0.5501 | 0.7255 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0419 | 0.0458 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0019 | 0.0419 | 0.1076 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0038 | 0.1268 | 0.1268 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.1139 | 0.1421 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.4333 | 0.5694 |
Schistosoma mansoni | lipoxygenase | 0.0019 | 0.0419 | 0.0458 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0034 | 0.1087 | 0.1087 |
Onchocerca volvulus | 0.0017 | 0.0339 | 0.1632 | |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.119 | 0.119 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0598 | 0.0697 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0027 | 0.0779 | 0.0938 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0339 | 0.0054 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0339 | 0.0054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0131 | 0.5501 | 0.5501 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0019 | 0.0419 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0077 | 0.0077 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.168 | 0.2144 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.3148 | 0.3148 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.1139 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.1377 | 0.1377 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1157 | 0.1445 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0131 | 0.5501 | 0.7255 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.1139 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0086 | 0.3449 | 0.3398 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0229 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1139 | 0.1139 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0034 | 0.1087 | 0.1087 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.1622 | 0.1622 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0127 | 0.532 | 0.532 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0131 | 0.5501 | 0.5501 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0293 | 0.0217 |
Brugia malayi | jmjC domain containing protein | 0.0127 | 0.532 | 0.5284 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0339 | 0.0339 |
Echinococcus granulosus | geminin | 0.0176 | 0.7552 | 0.7552 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0063 | 0.2438 | 1 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0034 | 0.1087 | 0.1087 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Onchocerca volvulus | 0.0019 | 0.0419 | 0.2134 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.1139 | 0.1139 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0339 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1139 | 0.1139 |
Schistosoma mansoni | phd/f-box containing protein | 0.0034 | 0.1087 | 0.1351 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0339 | 0.0054 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.1139 | 0.107 |
Schistosoma mansoni | polycystin 1-related | 0.0019 | 0.0419 | 0.0458 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1087 | 0.1087 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.119 | 0.1489 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0229 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0034 | 0.1087 | 0.1087 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0034 | 0.1087 | 0.3564 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.2561 | 1 |
Onchocerca volvulus | 0.0047 | 0.168 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1501 | 0.1501 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0419 | 0.0419 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0339 | 0.1632 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.1139 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0054 | 0.1988 | 0.2556 |
Brugia malayi | beta-lactamase | 0.0035 | 0.1139 | 0.107 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.1139 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0069 | 0.267 | 0.267 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0339 | 0.0054 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0448 | 0.0496 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.1139 | 0.3813 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0339 | 0.0264 |
Echinococcus granulosus | cathepsin l1 | 0.0012 | 0.0077 | 0.0077 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0416 | 0.0453 |
Onchocerca volvulus | 0.0017 | 0.0339 | 0.1632 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0419 | 0.0419 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0019 | 0.0419 | 0.0419 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0339 | 0.0264 |
Schistosoma mansoni | jumonji domain containing protein | 0.0034 | 0.1087 | 0.1351 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0105 | 0.4333 | 0.4333 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0448 | 0.0448 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.2561 | 1 |
Onchocerca volvulus | 0.0017 | 0.0339 | 0.1632 | |
Onchocerca volvulus | Cathepsin F homolog | 0.0017 | 0.0339 | 0.1632 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0034 | 0.1087 | 0.1351 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.2561 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0127 | 0.532 | 0.532 |
Echinococcus granulosus | RUN | 0.0019 | 0.0419 | 0.0419 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0077 | 0.0077 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0339 | 0.1632 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.1087 | 0.1087 |
Schistosoma mansoni | loxhd1 | 0.0019 | 0.0419 | 0.0458 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.1139 | 0.1139 |
Onchocerca volvulus | 0.0035 | 0.1139 | 0.6627 | |
Echinococcus multilocularis | phd:f box containing protein | 0.0034 | 0.1087 | 0.1087 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.1903 | 0.184 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0052 | 0.1916 | 0.7114 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Onchocerca volvulus | 0.0017 | 0.0339 | 0.1632 | |
Leishmania major | cysteine peptidase A (CPA) | 0.0017 | 0.0339 | 0.0054 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.4333 | 0.5694 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.1139 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.1139 | 0.3636 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0339 | 0.0264 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0012 | 0.0091 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0339 | 0.0339 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.1087 | 0.1087 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0105 | 0.4333 | 0.4333 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0339 | 0.0264 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0419 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1139 | 0.1139 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.1139 | 0.107 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1903 | 0.1903 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0419 | 0.0458 |
Onchocerca volvulus | 0.0017 | 0.0339 | 0.1632 | |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0293 | 0.0288 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0419 | 0.0419 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0339 | 0.0054 |
Loa Loa (eye worm) | bromodomain containing protein | 0.002 | 0.0447 | 0.0447 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0339 | 0.0339 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0326 | 0.0334 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0339 | 0.0339 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.1087 | 0.1018 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0293 | 0.0293 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.1087 | 0.1018 |
Onchocerca volvulus | 0.0017 | 0.0339 | 0.1632 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0339 | 0.0339 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0105 | 0.4333 | 0.4333 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.101 | 0.1248 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0034 | 0.1087 | 0.1351 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0339 | 0.0339 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.1139 | 0.5 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.168 | 0.1615 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0038 | 0.1268 | 0.1268 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0339 | 0.0339 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1802 | 0.1802 |
Onchocerca volvulus | 0.0019 | 0.0419 | 0.2134 | |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0027 | 0.0779 | 0.0779 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.7552 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0223 | 0.9715 | 1 |
Onchocerca volvulus | 0.0017 | 0.0339 | 0.1632 | |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0339 | 0.0339 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.1139 | 0.1139 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0293 | 0.0293 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.1139 | 0.3636 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1087 | 0.1087 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0419 | 0.0458 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0339 | 0.0339 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0339 | 0.0264 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.002 | 0.0448 | 0.0448 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0019 | 0.0416 | 0.0416 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.2561 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.1087 | 0.1087 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.1139 | 0.1139 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0034 | 0.1087 | 0.1087 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0027 | 0.0779 | 0.0779 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0339 | 0.0264 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.0905 | 0.0905 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0339 | 0.035 |
Echinococcus multilocularis | RUN | 0.0019 | 0.0419 | 0.0419 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0105 | 0.4333 | 0.5694 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.1903 | 0.184 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0105 | 0.4333 | 0.4333 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.1139 | 0.3636 |
Loa Loa (eye worm) | doublecortin family protein | 0.0019 | 0.0419 | 0.0419 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.1377 | 0.1377 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0419 | 0.0345 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.101 | 0.101 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.1903 | 0.1903 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0068 | 0.2649 | 0.344 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0339 | 0.0339 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0339 | 0.0339 |
Schistosoma mansoni | protein phosphatase 2C | 0.0034 | 0.1087 | 0.1351 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.1087 | 0.3403 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.1157 | 0.1089 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0293 | 0.0293 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.2561 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0293 | 0.0293 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0054 | 0.1988 | 0.1988 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0339 | 0.2462 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.006 | 0.23 | 0.883 |
Echinococcus multilocularis | zinc finger protein | 0.0024 | 0.0628 | 0.0628 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0293 | 0.0293 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = -7 % | DNDI: Inhibition of Human African Trypanosomiasis, SBRI 427, in vitro at 2 ug.mL-1 | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.