Detailed information for compound 1056888

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 258.269 | Formula: C15H14O4
  • H donors: 0 H acceptors: 0 LogP: 3.41 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1)C1OOC(OO1)c1ccccc1
  • InChi: 1S/C15H14O4/c1-11-6-5-9-13(10-11)15-18-16-14(17-19-15)12-7-3-2-4-8-12/h2-10,14-15H,1H3
  • InChiKey: JRAZFYWDQVKDCX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0156 0.0809 0.0809
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0205 0.0501
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.0055 0.0152
Brugia malayi nuclear hormone receptor family member nhr-6 0.0074 0.0331 0.0331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Echinococcus multilocularis fatty acid binding protein FABP2 0.0111 0.0547 0.0547
Brugia malayi hypoxia-induced factor 1 0.0174 0.0913 0.0913
Echinococcus granulosus neutral amino acid transporter A 0.1745 1 1
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.0055 0.0125
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0009 0.0009
Echinococcus multilocularis muscleblind protein 0.0331 0.1818 0.1818
Echinococcus multilocularis Excitatory amino acid transporter 0.1745 1 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0036
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0016 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0032 0.0032
Brugia malayi MH2 domain containing protein 0.0138 0.0704 0.0704
Loa Loa (eye worm) hypothetical protein 0.005 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0016 0.0028
Loa Loa (eye worm) hypothetical protein 0.009 0.0426 0.0426
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.0723 0.6626
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.000000038329 0.000000038329
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0156 0.0809 0.0809
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0019 0.0014 0.0014
Toxoplasma gondii exonuclease III APE 0.0057 0.0234 0.1959
Echinococcus granulosus Excitatory amino acid transporter 0.144804 1 1
Echinococcus multilocularis cpg binding protein 0.0061 0.0254 0.0254
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.1039 0.2592
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0216 0.1156 0.1156
Entamoeba histolytica hypothetical protein 0.0042 0.0145 0.0823
Brugia malayi Cathepsin L-like precursor 0.0019 0.0016 0.0016
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0172 0.0897 0.6103
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0016 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0156 0.0809 0.0809
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0583 0.3277 1
Plasmodium vivax SET domain protein, putative 0.009 0.0426 0.5498
Entamoeba histolytica hypothetical protein 0.0022 0.0032 0.0104
Brugia malayi hypothetical protein 0.0032 0.009 0.009
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0149 0.0767 0.0759
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0163 0.0485
Echinococcus granulosus neuropeptide s receptor 0.0465 0.2593 0.2593
Leishmania major hypothetical protein, conserved 0.0018 0.0009 0.0013
Schistosoma mansoni hypothetical protein 0.0079 0.0361 0.0361
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0005 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0299 0.1635 0.4083
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0317 0.0317
Mycobacterium leprae Probable lipase LipE 0.0149 0.0767 0.1552
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Schistosoma mansoni hypothetical protein 0.0035 0.0105 0.0105
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.003 0.0078
Brugia malayi hypothetical protein 0.0189 0.0998 0.0998
Brugia malayi bZIP transcription factor family protein 0.0097 0.0466 0.0466
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0069
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0055 0.0152
Echinococcus multilocularis FTZ F1 alpha 0.0156 0.0809 0.0809
Echinococcus multilocularis transfer RNA-Lys 0.0042 0.0145 0.0145
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0135 0.0326
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0025 0.0025
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0172 0.0897 0.0888
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0016 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1581 0.395
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0426 0.0426
Mycobacterium ulcerans aldehyde dehydrogenase 0.0203 0.1076 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0235 0.0235
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0402 0.2232 0.2232
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0032 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Echinococcus multilocularis snurportin 1 0.0651 0.3671 0.3671
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Plasmodium vivax hypothetical protein, conserved 0.0149 0.0767 1
Schistosoma mansoni hypothetical protein 0.0216 0.1156 0.1156
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0111 0.0547 0.0547
Onchocerca volvulus Bile acid receptor homolog 0.0156 0.0809 0.0809
Schistosoma mansoni lipoxygenase 0.0064 0.0274 0.0274
Mycobacterium ulcerans esterase/lipase LipP 0.0149 0.0767 0.7048
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0052 0.0205 0.0612
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0331 0.0998
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.009 0.0426 0.0426
Trypanosoma brucei hypothetical protein, conserved 0.0149 0.0767 0.2331
Loa Loa (eye worm) DR-78 0.0074 0.0331 0.0331
Echinococcus multilocularis protein dispatched 1 0.0047 0.0177 0.0177
Brugia malayi hypothetical protein 0.0083 0.0382 0.0382
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0009 0.0009
Echinococcus granulosus flap endonuclease 1 0.003 0.0078 0.0078
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0156 0.0809 0.0809
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0135 0.0397
Echinococcus granulosus expressed protein 0.0432 0.2405 0.2405
Echinococcus granulosus Polycystic kidney disease protein 0.0023 0.0036 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1581 0.395
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.2593 0.2593
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0156 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0041 0.0143 0.0143
Schistosoma mansoni fatty acid binding protein 0.0111 0.0547 0.0547
Schistosoma mansoni hypothetical protein 0.0651 0.3671 0.3671
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0639 0.3604 0.3604
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0622 0.3501 0.3501
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0019 0.0014 0.0014
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0032 0.0032
Schistosoma mansoni polycystin 1-related 0.0023 0.0036 0.0036
Echinococcus granulosus thioredoxin glutathione reductase 0.0076 0.0345 0.0345
Mycobacterium ulcerans lipase LipD 0.0149 0.0767 0.7048
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0156 0.0809 0.0809
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0163 0.1347
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0156 0.0809 0.0809
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0331 0.0997
Giardia lamblia GTOR 0.0052 0.0205 0.0985
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0156 0.0809 0.0809
Brugia malayi orphan nuclear receptor NR2E1 0.0074 0.0331 0.0331
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.001 0.0015
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0105 0.0105
Echinococcus multilocularis neutral amino acid transporter A 0.144804 1 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0117 0.0582 0.0582
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.001 0.001
Echinococcus multilocularis Excitatory amino acid transporter 0.144804 1 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.001 0.001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0192 0.1014 0.1014
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0032 0.0032
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.001 0.001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0036 0.0036
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.144804 1 0.5
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0055 0.0152
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.0055 0.0399
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.0767 0.2331
Brugia malayi nuclear hormone receptor 0.0156 0.0809 0.0809
Brugia malayi Cathepsin L-like precursor 0.0019 0.0016 0.0016
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0051 0.0197 0.0197
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0005 0.0005
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0032 0.0032
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0032 0.0032
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0331 0.0331
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.001 0.001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.001 0.001
Echinococcus multilocularis nuclear receptor nhr 48 0.0074 0.0331 0.0331
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0068 0.0298 0.0298
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0163 0.1347
Brugia malayi Cytochrome P450 family protein 0.0034 0.0099 0.0099
Echinococcus multilocularis carbonic anhydrase II 0.0583 0.3277 0.3277
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0192 0.0573
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0055 0.0152
Echinococcus multilocularis thioredoxin glutathione reductase 0.0076 0.0345 0.0345
Loa Loa (eye worm) excitatory amino acid transporter 0.144804 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Brugia malayi jmjC domain containing protein 0.0068 0.0298 0.0298
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0331 0.0331
Brugia malayi nuclear receptor RXR 0.0083 0.0382 0.0382
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0317 0.0317
Trichomonas vaginalis glucosylceramidase, putative 0.0299 0.1635 0.4083
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.003 0.0078
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0009 0.0009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0156 0.0809 0.0809
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.04 0.04
Echinococcus multilocularis excitatory amino acid transporter 2 0.144804 1 1
Echinococcus multilocularis excitatory amino acid transporter 2 0.1745 1 1
Echinococcus granulosus microtubule associated protein 2 0.0799 0.4529 0.4529
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.1039 0.2592
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0085 0.0397 0.0397
Schistosoma mansoni lipoxygenase 0.0023 0.0036 0.0036
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0192 0.1597
Schistosoma mansoni nuclear receptor 0.0074 0.0331 0.0331
Schistosoma mansoni hypothetical protein 0.0023 0.0036 0.0036
Trypanosoma brucei carbonic anhydrase-like protein 0.0583 0.3277 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0016 0.0016
Brugia malayi Pre-SET motif family protein 0.0622 0.3501 0.3501
Echinococcus multilocularis expressed conserved protein 0.0091 0.0428 0.0428
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0055 0.0127
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0583 0.3277 0.3277
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.1014 0.1014
Mycobacterium ulcerans putative regulatory protein 0.0042 0.0145 0.1098
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0016 0.0016
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0288 0.0288
Echinococcus granulosus FTZ F1 alpha 0.0156 0.0809 0.0809
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.0382 0.0382
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0145 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0331 0.0817
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0066 0.0154
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0135 0.0759
Brugia malayi hypothetical protein 0.0074 0.0331 0.0331
Trypanosoma cruzi cruzipain precursor, putative 0.0074 0.0331 0.0998
Onchocerca volvulus Protein ultraspiracle homolog 0.0156 0.0809 0.0809
Echinococcus granulosus muscleblind protein 0.0331 0.1818 0.1818
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.009 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0156 0.0809 0.0809
Schistosoma mansoni ap endonuclease 0.0057 0.0234 0.0234
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.001 0.001
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0135 0.0135
Leishmania major cathepsin L-like protease 0.0019 0.0016 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1581 0.395
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0346 0.1043
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0097 0.0466 0.0466
Treponema pallidum fructose-bisphosphate aldolase 0.029 0.1581 0.3531
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0583 0.3277 0.3277
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0055 0.0152
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0052 0.0205 0.0612
Brugia malayi Nuclear hormone receptor-like 1 0.0156 0.0809 0.0809
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0009 0.0009
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0009 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.1014 0.1014
Onchocerca volvulus 0.0056 0.0227 0.0227
Loa Loa (eye worm) cysteine protease 0.0019 0.0016 0.0016
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0084 0.0084
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1581 0.395
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0032 0.0032
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0066 0.0288 0.0288
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0156 0.0809 0.0809
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0015 0.0026
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0135 0.0135
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0156 0.0809 0.0809
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0135 0.0135
Schistosoma mansoni ran 0.0045 0.0163 0.0163
Brugia malayi ecdysteroid receptor 0.0156 0.0809 0.0809
Schistosoma mansoni retinoic acid receptor RXR 0.1048 0.597 0.597
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.1745 1 1
Schistosoma mansoni carbonic anhydrase-related 0.0216 0.1156 0.1156
Echinococcus granulosus excitatory amino acid transporter 2 0.1745 1 1
Echinococcus granulosus fatty acid binding protein FABP2 0.0111 0.0547 0.0547
Brugia malayi Thioredoxin reductase 0.0075 0.0339 0.0339
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0172 0.0897 0.0888
Brugia malayi hypothetical protein 0.0042 0.0145 0.0145
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1581 0.395
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0068 0.0298 0.0298
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0066 0.0288 0.0288
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0235 0.0235
Brugia malayi intermediate filament protein 0.0031 0.0084 0.0084
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0205 0.0205
Echinococcus granulosus jun protein 0.0097 0.0466 0.0466
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0104 0.0506 0.0506
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0055 0.0152
Trichomonas vaginalis ran, putative 0.0045 0.0163 0.0398
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.000000038329 0.000000038329
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0033 0.0033
Onchocerca volvulus 0.0104 0.0506 0.0506
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0076 0.0346 0.0346
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0583 0.3277 0.3277
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0069
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0032 0.0032
Schistosoma mansoni RAR-like nuclear receptor 0.0156 0.0809 0.0809
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0105 0.0105
Brugia malayi beta-lactamase family protein 0.0149 0.0767 0.0767
Schistosoma mansoni hypothetical protein 0.0639424 0.327335 0.0916028
Brugia malayi Cathepsin L-like precursor 0.0019 0.0016 0.0016
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0097 0.0462 0.0462
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0156 0.0809 0.0809
Trypanosoma cruzi hypothetical protein, conserved 0.0149 0.0767 0.2331
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0066 0.0154
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0055 0.0127
Toxoplasma gondii hypothetical protein 0.0216 0.1156 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0084 0.0198
Loa Loa (eye worm) hypothetical protein 0.0331 0.1818 0.1818
Echinococcus granulosus survival motor neuron protein 1 0.0274 0.1489 0.1489
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0216 0.1156 0.1156
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0036 0.0036
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.001 0.001
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.001 0.001
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0074 0.0331 0.1809
Onchocerca volvulus 0.0031 0.0084 0.0084
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0135 0.0326
Schistosoma mansoni hypothetical protein 0.006 0.025 0.025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0016 0.0028
Schistosoma mansoni hypothetical protein 0.0344 0.1892 0.1892
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0009 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0099 0.0099
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0066 0.0288 0.0279
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0064 0.0274 0.0274
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0103 0.0502 0.0502
Plasmodium vivax multidomain scavenger receptor, putative 0.0023 0.0036 0.0356
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0156 0.0809 0.0809
Echinococcus multilocularis excitatory amino acid transporter 3 0.1745 1 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0052 0.0205 0.0205
Trichomonas vaginalis glucosylceramidase, putative 0.0207 0.1101 0.2745
Loa Loa (eye worm) hypothetical protein 0.0156 0.0809 0.0809
Entamoeba histolytica hypothetical protein 0.0049 0.019 0.1111
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0135 0.0397
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0639424 0.327335 0.327335
Loa Loa (eye worm) CYP4Cod1 0.0022 0.003 0.003
Echinococcus multilocularis GPCR, family 2 0.0035 0.0105 0.0105
Brugia malayi conserved hypotetical protein 0.0074 0.0331 0.0331
Mycobacterium tuberculosis Probable reductase 0.0172 0.0897 0.0888
Brugia malayi hypothetical protein 0.005 0.0192 0.0192
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.0055 0.0603
Loa Loa (eye worm) hypothetical protein 0.0149 0.0767 0.0767
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0156 0.0809 0.0809
Trichomonas vaginalis glucosylceramidase, putative 0.0207 0.1101 0.2745
Brugia malayi nuclear receptor NHR-67 0.0074 0.0331 0.0331
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0032 0.0032
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.0055 0.0152
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0105 0.0105
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0773 0.4379 0.4379
Echinococcus multilocularis sodium:dicarboxylate symporter 0.1745 1 1
Loa Loa (eye worm) hypothetical protein 0.0156 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0149 0.0767 0.0767
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0055 0.0055
Brugia malayi ecdysone receptor 0.0074 0.0331 0.0331
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0192 0.0573
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0149 0.0767 0.0767
Giardia lamblia Fructose-bisphosphate aldolase 0.029 0.1581 1
Brugia malayi Nuclear hormone receptor E75 0.0074 0.0331 0.0331
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0583 0.3277 1
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0163 0.0713
Loa Loa (eye worm) beta-lactamase 0.0149 0.0767 0.0767
Echinococcus multilocularis lamin 0.0031 0.0084 0.0084
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0055 0.0127
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.024 0.0718
Leishmania major carbonic anhydrase-like protein 0.0583 0.3277 1
Schistosoma mansoni hypothetical protein 0.004 0.0135 0.0135
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.0338 0.0338
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0234 0.0234
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0055 0.0152
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0104 0.0506 0.0506
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.1014 0.1014
Chlamydia trachomatis glutamate symporter 0.1745 1 1
Echinococcus multilocularis Excitatory amino acid transporter 0.1745 1 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0029 0.0074
Echinococcus granulosus neutral amino acid transporter A 0.144804 1 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0283801 0.031502 0.031502
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.0055 0.0399
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0032 0.0032
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0074 0.0331 0.0331
Echinococcus granulosus single minded 2 0.0042 0.0145 0.0145
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0234 0.1173
Loa Loa (eye worm) hypothetical protein 0.0075 0.0338 0.0338
Plasmodium vivax glutathione reductase, putative 0.0075 0.0339 0.4353
Brugia malayi Cytochrome P450 family protein 0.0022 0.003 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0331 0.0817
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0005 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0142 0.0725 0.0725
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0163 0.2038
Loa Loa (eye worm) glutathione reductase 0.0075 0.0339 0.0339
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1581 0.395
Loa Loa (eye worm) hypothetical protein 0.0083 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Onchocerca volvulus 0.0117 0.0582 0.0582
Schistosoma mansoni survival motor neuron protein 0.0056 0.0227 0.0227
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0076 0.0346 0.0346
Leishmania major cathepsin L-like protease 0.0019 0.0016 0.0034
Treponema pallidum glutamate/aspartate transporter 0.0557883 0.259503 0.5
Schistosoma mansoni carbonic anhydrase-related 0.0216 0.1156 0.1156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.1039 0.2592
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0016 0.0016
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0156 0.0809 0.0809
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0331 0.0331
Schistosoma mansoni cellular tumor antigen P53 0.0057 0.0235 0.0235
Echinococcus granulosus carbonic anhydrase 0.0216 0.1156 0.1156
Plasmodium falciparum importin beta, putative 0.0061 0.0257 0.2159
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor 0.0074 0.0331 0.0331
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0462 0.0462
Mycobacterium tuberculosis Probable esterase LipL 0.0149 0.0767 0.0759
Schistosoma mansoni ran 0.0045 0.0163 0.0163
Echinococcus granulosus intermediate filament protein 0.0031 0.0084 0.0084
Trypanosoma cruzi target of rapamycin kinase 3 0.0041 0.0143 0.0424
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0074 0.0331 0.0331
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0052 0.0205 0.0612
Brugia malayi Steroid receptor seven-up type 2 0.0156 0.0809 0.0809
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0104 0.0506 0.0506
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0016 0.0016
Brugia malayi Calcitonin receptor-like protein seb-1 0.011 0.0539 0.0539
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.144804 1 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0234 0.07
Brugia malayi Uncoordinated protein 44 0.0017 0.000000038329 0.000000038329
Echinococcus granulosus neutral amino acid transporter 0.1745 1 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0052 0.0205 0.0612
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0135 0.0326
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0234 0.07
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0216 0.1156 0.1156
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0036 0.0036
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0033 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0066 0.0154
Schistosoma mansoni hypothetical protein 0.0344 0.1892 0.1892
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0135 0.0326
Loa Loa (eye worm) hypothetical protein 0.0031 0.0081 0.0081
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0216 0.1156 0.1156
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.002 0.0039
Echinococcus granulosus phd:f box containing protein 0.0018 0.0009 0.0009
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0032 0.0032
Onchocerca volvulus 0.0103 0.0502 0.0502
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0163 0.0163
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0135 0.0326
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0135 0.0326
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0078 0.0605
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0205 0.0612
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0216 0.1156 0.1156
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0032 0.0032
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0117 0.0583 0.0583
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0016 0.0028
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0163 0.0163
Brugia malayi Nuclear hormone receptor E75 0.0074 0.0331 0.0331
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0149 0.0767 0.7048
Echinococcus granulosus cathepsin l1 0.0019 0.0016 0.0016
Mycobacterium ulcerans aldehyde dehydrogenase 0.0203 0.1076 1
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0074 0.0331 0.0331
Loa Loa (eye worm) doublecortin family protein 0.0023 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0066 0.0154
Brugia malayi Isocitrate dehydrogenase 0.0018 0.001 0.001
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0104 0.0506 0.0506
Echinococcus granulosus beta LACTamase domain containing family member 0.0149 0.0767 0.0767
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0032 0.0032
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.009 0.0426 0.3635
Leishmania major cathepsin L-like protease 0.0019 0.0016 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0055 0.0127
Echinococcus granulosus snurportin 1 0.0651 0.3671 0.3671
Trypanosoma brucei glucosidase, putative 0.004 0.0135 0.0397
Onchocerca volvulus 0.0023 0.0036 0.0036
Onchocerca volvulus 0.0074 0.0331 0.0331
Onchocerca volvulus 0.0117 0.0582 0.0582
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0163 0.0485
Entamoeba histolytica hypothetical protein 0.0042 0.0145 0.0823
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.000000038329 0.000000038329
Echinococcus multilocularis cysteine protease 0.0019 0.0016 0.0016
Schistosoma mansoni nuclear receptor nhr-48 0.0074 0.0331 0.0331
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0462 0.0462
Brugia malayi hypothetical protein 0.0022 0.0032 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Brugia malayi nuclear hormone receptor 0.032 0.1754 0.1754
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0234 0.07
Brugia malayi M-phase phosphoprotein, mpp8 0.0117 0.0582 0.0582
Brugia malayi Muscleblind-like protein 0.0331 0.1818 0.1818
Onchocerca volvulus Huntingtin homolog 0.0142 0.0725 0.0725
Entamoeba histolytica Flap nuclease, putative 0.003 0.0078 0.0398
Echinococcus multilocularis cysteine protease 0.0019 0.0016 0.0016
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1599 0.9158 0.9158
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0262 0.0262
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0111 0.0547 0.0547
Echinococcus granulosus expressed conserved protein 0.0091 0.0428 0.0428
Schistosoma mansoni nuclear hormone receptor 0.0156 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0274 0.1489 0.1489
Echinococcus granulosus tumor protein p63 0.0391 0.2168 0.2168
Loa Loa (eye worm) hypothetical protein 0.0083 0.0382 0.0382
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.0767 0.191
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0084 0.0084
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0143 0.0143
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1581 0.395
Schistosoma mansoni aryl hydrocarbon receptor 0.0056 0.023 0.023
Schistosoma mansoni alpha-glucosidase 0.0155 0.08 0.08
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0234 0.0573
Trichomonas vaginalis esterase, putative 0.0149 0.0767 0.191
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0016 0.0028
Echinococcus multilocularis excitatory amino acid transporter 2 0.1745 1 1
Echinococcus granulosus neutral amino acid transporter 0.144804 1 1
Echinococcus granulosus lamin 0.0031 0.0084 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0156 0.0809 0.0809
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0149 0.0767 0.0759
Echinococcus multilocularis Excitatory amino acid transporter 0.144804 1 1
Loa Loa (eye worm) ctsf protein 0.0019 0.0016 0.0016
Brugia malayi hypothetical protein 0.0142 0.0725 0.0725
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0156 0.0809 0.0809
Echinococcus granulosus RUN 0.0023 0.0036 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0299 0.1635 0.4083
Schistosoma mansoni hypothetical protein 0.004 0.0135 0.0135
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0954 0.5422 0.5417
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0074 0.0331 0.0331
Echinococcus granulosus neutral amino acid transporter A 0.144804 1 1
Schistosoma mansoni alpha glucosidase 0.004 0.0135 0.0135
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0074 0.0331 0.0331
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0135 0.0326
Echinococcus granulosus carbonic anhydrase II 0.0583 0.3277 0.3277
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0083 0.0382 0.0382
Schistosoma mansoni steroid hormone receptor ad4bp 0.0156 0.0809 0.0809
Schistosoma mansoni rab6-interacting 0.0023 0.0036 0.0036
Echinococcus multilocularis ubiquitin specific protease 41 0.0074 0.0331 0.0331
Brugia malayi Cathepsin L-like precursor 0.0019 0.0016 0.0016
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0032 0.0032
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0076 0.0346 0.0346
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Echinococcus granulosus lysosomal alpha glucosidase 0.018 0.0945 0.0945
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.001 0.0015
Echinococcus multilocularis carbonic anhydrase 0.0216 0.1156 0.1156
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.0055 0.0399
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.0055 0.0603
Brugia malayi Flap endonuclease-1 0.003 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0022 0.0033 0.0033
Leishmania major cathepsin L-like protease 0.0019 0.0016 0.0034
Schistosoma mansoni hypothetical protein 0.0035 0.0105 0.0105
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0032 0.0032
Echinococcus multilocularis musashi 0.0031 0.0084 0.0084
Brugia malayi PXA domain containing protein 0.0022 0.0032 0.0032
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.019 0.0464
Schistosoma mansoni intermediate filament proteins 0.0031 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0331 0.0817
Echinococcus granulosus fatty acid binding protein FABP2 0.0111 0.0547 0.0547
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0234 0.0573
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0016 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0032 0.0032
Onchocerca volvulus 0.0149 0.0767 0.0767
Schistosoma mansoni coup transcription factor 0.0156 0.0809 0.0809
Plasmodium vivax thioredoxin reductase, putative 0.0075 0.0339 0.4353
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0064 0.0274 0.0274
Toxoplasma gondii thioredoxin reductase 0.0075 0.0339 0.2878
Brugia malayi isocitrate dehydrogenase 0.0018 0.001 0.001
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0078 0.0225
Brugia malayi nuclear hormone receptor family member odr-7 0.0074 0.0331 0.0331
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0203 0.1076 0.1068
Plasmodium vivax vivapain-2 0.0019 0.0016 0.0094
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.1039 0.2592
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0149 0.0767 0.0759
Echinococcus granulosus carbonic anhydrase 0.0216 0.1156 0.1156
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0203 0.1076 0.3275
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0083 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.0105
Echinococcus granulosus Excitatory amino acid transporter 0.144804 1 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0036
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0172 0.0897 0.0888
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0032 0.0032
Echinococcus multilocularis flap endonuclease 1 0.003 0.0078 0.0078
Onchocerca volvulus 0.0019 0.0016 0.0016
Trypanosoma cruzi trypanothione reductase, putative 0.0075 0.0339 0.1022
Echinococcus granulosus histone lysine methyltransferase setb 0.009 0.0426 0.0426
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0156 0.0809 0.0809
Brugia malayi CXXC zinc finger family protein 0.0057 0.0235 0.0235
Echinococcus multilocularis excitatory amino acid transporter 3 0.144804 1 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.018 0.0945 0.0945
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0426 0.0426
Plasmodium falciparum LCCL domain-containing protein 0.0023 0.0036 0.0236
Toxoplasma gondii aldehyde dehydrogenase 0.0203 0.1076 0.9303
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.1745 1 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0257 0.077
Loa Loa (eye worm) thioredoxin reductase 0.0075 0.0339 0.0339
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0032 0.0032
Onchocerca volvulus 0.0057 0.0235 0.0235
Schistosoma mansoni nuclear receptor 0.0074 0.0331 0.0331
Onchocerca volvulus 0.0156 0.0809 0.0809
Brugia malayi RNA, U transporter 1 0.0173 0.0907 0.0907
Trichomonas vaginalis glucosylceramidase, putative 0.0299 0.1635 0.4083
Toxoplasma gondii cathepsin CPL 0.0019 0.0016 0.0062
Brugia malayi hypothetical protein 0.0023 0.0036 0.0036
Leishmania major hypothetical protein, conserved 0.005 0.0192 0.0573
Onchocerca volvulus 0.0149 0.0767 0.0767
Brugia malayi Cathepsin L-like precursor 0.0019 0.0016 0.0016
Entamoeba histolytica hypothetical protein 0.0022 0.0032 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0156 0.0809 0.0809
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0074 0.0331 0.0331
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0067 0.0294 0.0885
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0156 0.0809 0.0809
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.1581 1
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0639 0.3604 0.3604
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Echinococcus multilocularis neutral amino acid transporter A 0.1745 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0331 0.0998
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0156 0.0809 0.0809
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0032 0.0032
Mycobacterium ulcerans hypothetical protein 0.0149 0.0767 0.7048
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0105 0.0105
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0331 0.1818 0.1818
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0097 0.0466 0.0466
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0078 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0143 0.0347
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.004 0.0135 0.0135
Schistosoma mansoni carbonic anhydrase 0.0216 0.1156 0.1156
Brugia malayi jmjC domain containing protein 0.0018 0.0009 0.0009
Plasmodium vivax vivapain-2 0.0019 0.0016 0.0094
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0026 0.0055 0.0233
Onchocerca volvulus Huntingtin homolog 0.0142 0.0725 0.0725
Echinococcus multilocularis carbonic anhydrase 0.0216 0.1156 0.1156
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0773 0.4379 0.4379
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0702 0.0702
Loa Loa (eye worm) hypothetical protein 0.0095 0.0451 0.0451
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0024 0.0024
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0078 0.0225
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0032 0.0032
Mycobacterium tuberculosis Probable lipase LipE 0.0149 0.0767 0.0759
Schistosoma mansoni jun-related protein 0.0079 0.0361 0.0361
Schistosoma mansoni fatty acid binding protein 0.0111 0.0547 0.0547
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.001 0.001
Brugia malayi PAS domain containing protein 0.0056 0.023 0.023
Mycobacterium ulcerans beta-lactamase 0.0149 0.0767 0.7048
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0471 0.0471
Brugia malayi jmjC domain containing protein 0.0018 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0084 0.0198
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Brugia malayi Cytochrome P450 family protein 0.0022 0.003 0.003
Echinococcus multilocularis neutral amino acid transporter A 0.1745 1 1
Schistosoma mansoni hypothetical protein 0.0056 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0189 0.0998 0.0998
Echinococcus multilocularis RUN 0.0023 0.0036 0.0036
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0203 0.1076 0.1076
Onchocerca volvulus 0.0019 0.0016 0.0016
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0026 0.0055 0.0233
Echinococcus granulosus cpg binding protein 0.0061 0.0254 0.0254
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0192 0.1597
Plasmodium falciparum thioredoxin reductase 0.0026 0.0055 0.0399
Echinococcus granulosus geminin 0.0344 0.1892 0.1892
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0489 0.2733 0.2733
Plasmodium falciparum thioredoxin reductase 0.0075 0.0339 0.2878
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.2593 0.2593
Loa Loa (eye worm) hypothetical protein 0.0216 0.1156 0.1156
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0032 0.0032
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0462 0.2851
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0234 0.0234
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0055 0.0152
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0074 0.0331 0.0331
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0016 0.0062
Leishmania major cathepsin L-like protease 0.0019 0.0016 0.0034
Echinococcus granulosus excitatory amino acid transporter 2 0.144804 1 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0972131 0.604105 0.411452
Brugia malayi nuclear receptor NHR-88 0.0156 0.0809 0.0809
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0076 0.0346 0.1043
Mycobacterium tuberculosis Probable oxidoreductase 0.0191 0.1008 0.0999
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0156 0.0809 0.0809
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.0945 0.0945
Brugia malayi hypothetical protein 0.0076 0.0346 0.0346
Brugia malayi steroid hormone receptor 0.0156 0.0809 0.0809
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0032 0.0032
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.0723 0.0714
Loa Loa (eye worm) nuclear receptor NHR-67 0.0074 0.0331 0.0331
Echinococcus multilocularis microtubule associated protein 2 0.0799 0.4529 0.4529
Brugia malayi jmjC domain containing protein 0.0071 0.0317 0.0317
Trichomonas vaginalis penicillin-binding protein, putative 0.0149 0.0767 0.191
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0639 0.3604 0.3604
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0061 0.0257 0.0257
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0083 0.0382 0.0382
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.1745 1 1
Echinococcus multilocularis tumor protein p63 0.0391 0.2168 0.2168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0084 0.0198
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0083 0.0382 0.0382
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.144804 1 0.5
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0163 0.0163
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0074 0.0331 0.2011
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.1039 0.2592
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0299 0.1635 0.1635
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0156 0.0809 0.0809
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.001 0.0007
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0016 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0069
Echinococcus multilocularis dnaJ subfamily B 0.0816 0.4628 0.4628
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0149 0.0767 0.0767
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0066 0.0154
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0016 0.0028
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.001 0.0015
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0773 0.4379 0.4379
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0076 0.0346 0.0346
Brugia malayi CHE-14 protein 0.0041 0.0143 0.0143
Schistosoma mansoni hypothetical protein 0.0035 0.0105 0.0105
Loa Loa (eye worm) fibroinase 0.0019 0.0016 0.0016
Echinococcus multilocularis Ankyrin 0.0017 0.0001 0.0001
Echinococcus granulosus lamin dm0 0.0031 0.0084 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0161 0.0391
Leishmania major trypanothione reductase 0.0075 0.0339 0.1022
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.003 0.003
Brugia malayi Death domain containing protein 0.0017 0.000000038329 0.000000038329
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0583 0.3277 0.3277
Mycobacterium tuberculosis Probable dehydrogenase 0.0172 0.0897 0.0888
Schistosoma mansoni aldehyde dehydrogenase 0.0203 0.1076 0.1076
Echinococcus multilocularis ecdysone induced protein 78C 0.0156 0.0809 0.0809
Echinococcus multilocularis jun protein 0.0097 0.0466 0.0466
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0032 0.0032
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0016 0.0034
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0032 0.0032
Trichomonas vaginalis importin beta-1, putative 0.0049 0.019 0.0464
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0066 0.0154
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0075 0.0339 0.033
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0105 0.0105
Schistosoma mansoni single-minded 0.0056 0.023 0.023
Trichomonas vaginalis glucosylceramidase, putative 0.0299 0.1635 0.4083
Loa Loa (eye worm) hypothetical protein 0.0156 0.0809 0.0809
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0156 0.0809 0.0809
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0331 0.0997
Loa Loa (eye worm) steroid hormone receptor 0.0156 0.0809 0.0809
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0016 0.0016
Echinococcus multilocularis survival motor neuron protein 1 0.0274 0.1489 0.1489
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.0055 0.0399
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0055 0.0055
Echinococcus granulosus ecdysone induced protein 78C 0.0156 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0032 0.0032
Echinococcus granulosus ubiquitin specific protease 41 0.0074 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Echinococcus multilocularis lysine specific demethylase 5A 0.0068 0.0298 0.0298
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0009 0.0009
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0551 0.4726
Echinococcus multilocularis Polycystic kidney disease protein 0.0023 0.0036 0.0036
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0143 0.0347
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0016 0.0028
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0135 0.0326
Loa Loa (eye worm) hypoxia-induced factor 1 0.0174 0.0913 0.0913
Echinococcus granulosus dnaJ subfamily B 0.0816 0.4628 0.4628
Brugia malayi hypothetical protein 0.0083 0.0382 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0205 0.0501
Echinococcus granulosus Ankyrin 0.0017 0.0001 0.0001
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0046 0.0127
Echinococcus multilocularis muscleblind protein 1 0.0331 0.1818 0.1818
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0128 0.0308
Loa Loa (eye worm) hypothetical protein 0.0216 0.1156 0.1156
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0639424 0.327335 0.0916028
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0036 0.0036
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0172 0.0897 0.0888
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.0767 0.191
Schistosoma mansoni cpg binding protein 0.0061 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0156 0.0809 0.0809
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.003 0.003
Entamoeba histolytica hypothetical protein 0.0042 0.0145 0.0823
Loa Loa (eye worm) hypothetical protein 0.0149 0.0767 0.0767
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0234 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0069
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0016 0.0016
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0005 0.0005
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.1581 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0128 0.0308
Schistosoma mansoni alpha-glucosidase 0.0155 0.08 0.08
Echinococcus granulosus Nuclear hormone receptor HR96 0.0074 0.0331 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0069
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0192 0.0573
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0253
Plasmodium falciparum glutathione reductase 0.0026 0.0055 0.0399
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0156 0.0809 0.0809
Mycobacterium tuberculosis Conserved protein 0.0149 0.0767 0.0759
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0128 0.0308
Onchocerca volvulus 0.0031 0.0084 0.0084
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0009 0.0009
Echinococcus granulosus carbonic anhydrase 0.0216 0.1156 0.1156
Leishmania major hypothetical protein, conserved 0.0149 0.0767 0.2331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0128 0.0308
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0005 0.0005
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0156 0.0809 0.0809
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Loa Loa (eye worm) carbonic anhydrase 3 0.0583 0.3277 0.3277
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.144804 1 1
Schistosoma mansoni rab6-interacting 0.0023 0.0036 0.0036
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0317 0.0317
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0032 0.0032
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0076 0.0346 0.0346
Schistosoma mansoni carbonic anhydrase-related 0.0216 0.1156 0.1156
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0016 0.0028
Brugia malayi nuclear receptor NHR-88 0.0074 0.0331 0.0331
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.0055 0.0045
Brugia malayi PXA domain containing protein 0.0022 0.0032 0.0032
Brugia malayi follicle stimulating hormone receptor 0.0489 0.2733 0.2733
Schistosoma mansoni flap endonuclease-1 0.0027 0.0061 0.0061
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0055 0.0152
Entamoeba histolytica Ran family GTPase 0.0045 0.0163 0.0942
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0143 0.0347
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.0055 0.0152
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0025 0.0025
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0032 0.0032
Echinococcus multilocularis fatty acid binding protein FABP2 0.0111 0.0547 0.0547
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0702 0.0702
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0009
Brugia malayi Pre-SET motif family protein 0.009 0.0426 0.0426
Brugia malayi hypothetical protein 0.0274 0.1489 0.1489
Trichomonas vaginalis glucosylceramidase, putative 0.0299 0.1635 0.4083
Brugia malayi hypothetical protein 0.0074 0.0331 0.0331
Echinococcus multilocularis excitatory amino acid transporter 2 0.144804 1 1
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0032 0.0032
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0234 0.07
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0317 0.0317
Treponema pallidum glutamate/aspartate transporter 0.0773 0.4379 1
Onchocerca volvulus 0.0019 0.0016 0.0016
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0016 0.0016
Mycobacterium tuberculosis Conserved protein 0.0149 0.0767 0.0759
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Plasmodium falciparum glutathione reductase 0.0075 0.0339 0.2878
Brugia malayi hypothetical protein 0.0023 0.0036 0.0036
Schistosoma mansoni loxhd1 0.0023 0.0036 0.0036
Brugia malayi indoleamine 2,3-dioxygenase 0.0639424 0.327335 0.305455
Brugia malayi hypothetical protein 0.0022 0.0032 0.0032
Loa Loa (eye worm) nuclear hormone receptor 0.0074 0.0331 0.0331
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0009 0.0009
Onchocerca volvulus 0.0042 0.0145 0.0145
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0156 0.0809 0.0809
Trypanosoma brucei trypanothione reductase 0.0075 0.0339 0.1022
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.019 0.0464
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0052 0.0205 0.0612
Echinococcus granulosus excitatory amino acid transporter 3 0.144804 1 1
Chlamydia trachomatis neutral amino acid transporter 0.0773 0.4379 0.4348
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0083 0.0382 0.0382
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.001 0.0015
Echinococcus multilocularis geminin 0.0344 0.1892 0.1892
Onchocerca volvulus 0.0019 0.0016 0.0016
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0028 0.0028
Echinococcus granulosus Excitatory amino acid transporter 0.1745 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0156 0.0809 0.0809
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0105 0.0105
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0009 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.0203 0.1076 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0105 0.0105
Onchocerca volvulus 0.0707 0.3998 0.3998
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0163 0.0485
Echinococcus granulosus Excitatory amino acid transporter 0.1745 1 1
Schistosoma mansoni retinoic acid receptor RXR 0.0972131 0.604105 0.465365
Echinococcus granulosus transcription factor Dp 1 0.0044 0.016 0.016
Onchocerca volvulus 0.0019 0.0016 0.0016
Onchocerca volvulus 0.0074 0.0331 0.0331
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0234 0.1945
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0143 0.0143
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0016 0.0062
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0234 0.0234
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0234 0.0224
Chlamydia trachomatis glutamate symporter 0.144804 1 1
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0773 0.4379 0.4379
Onchocerca volvulus 0.0057 0.0235 0.0235
Brugia malayi Cathepsin L-like precursor 0.0019 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0032 0.0069
Leishmania major importin beta-1 subunit, putative 0.0049 0.019 0.0566
Leishmania major cathepsin L-like protease 0.0074 0.0331 0.0998
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.1014 0.1014
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0156 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.011 0.0539 0.0539
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.0767 0.191
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0331 0.0997
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0929721 0.568825 0.417722
Schistosoma mansoni cpg binding protein 0.0057 0.0235 0.0235
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0016 0.0062
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.0767 0.0767
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0192 0.2415
Brugia malayi Excitatory amino acid transporter 0.144804 1 1
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.1745 1 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0191 0.1008 1
Leishmania major GTP-binding protein, putative 0.0045 0.0163 0.0485
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0135 0.0397
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0078 0.0184
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0083 0.0382 0.0382
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.1014 0.1014
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.0055 0.0125
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0135 0.1097
Schistosoma mansoni hypothetical protein 0.0075 0.0338 0.0338
Leishmania major cathepsin L-like protease 0.0074 0.0331 0.0998
Schistosoma mansoni microtubule-associated protein tau 0.0799 0.4529 0.4529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0191 0.1008 0.0999
Schistosoma mansoni thyroid hormone receptor 0.0156 0.0809 0.0809
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0205 0.0501
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0099 0.0237
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0156 0.0809 0.0809
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0288 0.0288
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0149 0.0767 0.0767
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.001 0.0007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0234 0.1959
Loa Loa (eye worm) hypothetical protein 0.0083 0.0382 0.0382
Loa Loa (eye worm) MH2 domain-containing protein 0.0138 0.0704 0.0704
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.2593 0.2593
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0016 0.0016
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0005 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0016 0.0016
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0009 0.0009
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0135 0.0759
Echinococcus multilocularis thyroid hormone receptor alpha 0.0156 0.0809 0.0809
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0028 0.0028
Brugia malayi hypothetical protein 0.0117 0.0583 0.0583
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0082 0.0193
Brugia malayi Glycosyl hydrolases family 31 protein 0.018 0.0945 0.0945
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0016 0.0028
Echinococcus granulosus excitatory amino acid transporter 2 0.1745 1 1
Schistosoma mansoni jumonji domain containing protein 0.0068 0.0298 0.0298
Schistosoma mansoni hypothetical protein 0.0639 0.3604 0.3604
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0066 0.0154
Mycobacterium tuberculosis Probable hydrolase 0.0149 0.0767 0.0759
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0032 0.0032
Echinococcus granulosus neutral amino acid transporter A 0.1745 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Loa Loa (eye worm) hypothetical protein 0.0156 0.0809 0.0809
Echinococcus granulosus excitatory amino acid transporter 2 0.144804 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0128 0.0308
Loa Loa (eye worm) hypothetical protein 0.0149 0.0767 0.0767
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0041 0.0143 0.0424
Leishmania major cytochrome p450-like protein 0.0022 0.003 0.0078
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0074 0.0331 0.0331
Trichomonas vaginalis D-aminoacylase, putative 0.0149 0.0767 0.191
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0032 0.0032
Trypanosoma brucei cytochrome P450, putative 0.0022 0.003 0.0078
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0055 0.0127
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0149 0.0767 0.0767
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0143 0.0143
Brugia malayi bHLH-PAS transcription factor 0.0042 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0055 0.0152
Schistosoma mansoni thyroid hormone receptor 0.0156 0.0809 0.0809
Echinococcus granulosus excitatory amino acid transporter 3 0.1745 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0128 0.0308
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0426 0.0426
Echinococcus granulosus importin subunit beta 1 0.0061 0.0257 0.0257
Loa Loa (eye worm) excitatory amino acid transporter 0.1745 1 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.032 0.1754 0.1754
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0009 0.0009
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0163 0.0163
Mycobacterium leprae conserved hypothetical protein 0.0149 0.0767 0.1552
Echinococcus granulosus nuclear receptor nhr 48 0.0074 0.0331 0.0331
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0066 0.0288 0.0866
Brugia malayi Importin beta-1 subunit 0.0061 0.0257 0.0257
Trichomonas vaginalis set domain proteins, putative 0.0707 0.3997 1
Loa Loa (eye worm) hypothetical protein 0.0142 0.0725 0.0725
Echinococcus multilocularis beta LACTamase domain containing family member 0.0149 0.0767 0.0767
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0055 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0143 0.0347
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0331 0.0998
Schistosoma mansoni hypothetical protein 0.0639 0.3604 0.3604
Brugia malayi nuclear receptor RXR 0.0074 0.0331 0.0331
Echinococcus multilocularis neutral amino acid transporter A 0.144804 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.1039 0.2592
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0032 0.0032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0156 0.0809 0.0809
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.1014 0.1014
Plasmodium vivax importin-beta 2, putative 0.0061 0.0257 0.3266
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0346 0.1043
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.1014 0.1014
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0032 0.0032
Onchocerca volvulus Glucosylceramidase homolog 0.0196 0.1039 0.1039
Echinococcus multilocularis transcription factor Dp 1 0.0044 0.016 0.016
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0005 0.0005
Leishmania major cathepsin L-like protease 0.0074 0.0331 0.0998
Treponema pallidum glutamate transporter 0.0557883 0.259503 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Echinococcus multilocularis neutral amino acid transporter A 0.1745 1 1
Schistosoma mansoni cpg binding protein 0.0061 0.0254 0.0254
Echinococcus multilocularis importin subunit beta 1 0.0061 0.0257 0.0257
Echinococcus granulosus Nuclear hormone receptor HR96 0.0074 0.0331 0.0331
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0078 0.0155
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0288 0.2467
Echinococcus granulosus sodium:dicarboxylate symporter 0.1745 1 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.0331 0.0997
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0032 0.0069
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0041 0.0143 0.0424
Loa Loa (eye worm) hypothetical protein 0.0156 0.0809 0.0809
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0143 0.0143
Brugia malayi tailless protein 0.0074 0.0331 0.0331
Onchocerca volvulus Excitatory amino acid transporter homolog 0.1745 1 1
Schistosoma mansoni hypothetical protein 0.0639424 0.327335 0.0916028
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0205 0.0205
Schistosoma mansoni lamin 0.0031 0.0084 0.0084
Onchocerca volvulus 0.0149 0.0767 0.0767
Onchocerca volvulus Excitatory amino acid transporter homolog 0.144804 1 1
Schistosoma mansoni hypothetical protein 0.0816 0.4628 0.4628
Trichomonas vaginalis conserved hypothetical protein 0.002 0.002 0.0039
Schistosoma mansoni ap endonuclease 0.0057 0.0234 0.0234
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0234 0.018
Schistosoma mansoni aldehyde dehydrogenase 0.0203 0.1076 0.1076
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.0945 0.0945
Loa Loa (eye worm) pigment dispersing factor receptor c 0.011 0.0539 0.0539
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.1581 0.395
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0082 0.0193
Schistosoma mansoni hypothetical protein 0.0042 0.0145 0.0145
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0032 0.0032
Echinococcus multilocularis carbonic anhydrase 0.0216 0.1156 0.1156
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0156 0.0809 0.0809
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0055 0.0152
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0203 0.1076 0.1076
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0288 0.2467
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0192 0.1597
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0191 0.1008 0.0999
Mycobacterium tuberculosis Conserved protein 0.0149 0.0767 0.0759
Plasmodium falciparum flap endonuclease 1 0.003 0.0078 0.0605
Onchocerca volvulus 0.0019 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0216 0.1156 0.1156
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0145 0.0145
Brugia malayi beta-lactamase family protein 0.0149 0.0767 0.0767
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0216 0.1156 0.1156
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0299 0.1635 0.1635
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0055 0.0055
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0257 0.077
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0035 0.0105 0.0105
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0156 0.0809 0.0809
Brugia malayi Doublecortin family protein 0.0023 0.0036 0.0036
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0052 0.0205 0.1207
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.011 0.0539 0.0539
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0966 0.5492 0.5492
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0052 0.0205 0.1207
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.001 0.0007
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0009 0.0009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0055 0.0152
Echinococcus granulosus GPCR family 2 0.0035 0.0105 0.0105
Entamoeba histolytica hypothetical protein 0.0042 0.0145 0.0823
Toxoplasma gondii ABC1 family protein 0.0149 0.0767 0.6611
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0156 0.0809 0.0809
Echinococcus multilocularis neutral amino acid transporter A 0.144804 1 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0651 0.3671 0.3671
Echinococcus granulosus retinoic acid receptor rxr beta a 0.1048 0.597 0.597
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0462 0.0462
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0128 0.0308
Echinococcus granulosus thyroid hormone receptor alpha 0.0074 0.0331 0.0331
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0074 0.0331 0.0331
Brugia malayi photoreceptor-specific nuclear receptor 0.0156 0.0809 0.0809
Brugia malayi indoleamine 2,3-dioxygenase 0.0639 0.3604 0.3604
Plasmodium falciparum carbonic anhydrase 0.0216 0.1156 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.001 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0143 0.0347
Echinococcus multilocularis sodium:dicarboxylate symporter 0.144804 1 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0192 0.1014 0.1014
Onchocerca volvulus 0.0023 0.0036 0.0036
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0076 0.0346 0.2109
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.1039 0.2592
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0076 0.0346 0.1043
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0234 0.1391
Schistosoma mansoni hypothetical protein 0.004 0.0135 0.0135
Brugia malayi Protein kinase domain containing protein 0.0017 0.000000038329 0.000000038329
Loa Loa (eye worm) transcription factor SMAD2 0.0138 0.0704 0.0704
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.019 0.0566
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0331 0.0331
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0016
Brugia malayi glutathione reductase 0.0075 0.0339 0.0339
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0026 0.0055 0.0233
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0156 0.0809 0.0809
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0055 0.0127
Echinococcus granulosus sodium:dicarboxylate symporter 0.144804 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0135 0.0326
Schistosoma mansoni nuclear hormone receptor 0.0074 0.0331 0.0331
Echinococcus multilocularis protein patched 0.0041 0.0143 0.0143
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0074 0.0331 0.0331
Mycobacterium tuberculosis Probable lipase LipD 0.0149 0.0767 0.0759
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0078 0.0225
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0626 0.0626
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0234 0.0414
Treponema pallidum glutamate transporter 0.0773 0.4379 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0074 0.0331 0.0331
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.0382 0.0382
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0583 0.3277 0.3277
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0055 0.0127
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0052 0.0205 0.0205
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0052 0.0205 0.0205
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.0128 0.1036
Onchocerca volvulus 0.0019 0.0016 0.0016
Echinococcus multilocularis lamin dm0 0.0031 0.0084 0.0084
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0074 0.0331 0.0331
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0135 0.0135
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0055 0.0152
Brugia malayi SET domain containing protein 0.0018 0.0006 0.0006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0156 0.0809 0.0809
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0009 0.0013
Brugia malayi jmjC domain containing protein 0.0018 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0022 0.0032 0.0104
Loa Loa (eye worm) hypothetical protein 0.0074 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0246 0.1327 0.1327
Loa Loa (eye worm) hypothetical protein 0.0149 0.0767 0.0767
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0009 0.0009
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0074 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0156 0.0809 0.0809
Onchocerca volvulus 0.0076 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0083 0.0382 0.0382
Schistosoma mansoni lamin 0.0031 0.0084 0.0084
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0156 0.0809 0.0809
Echinococcus granulosus nuclear factor of activated T cells 5 0.0085 0.0397 0.0397
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0234 0.2963
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0143 0.0347
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0032 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0055 0.0152
Schistosoma mansoni importin beta-1 0.0061 0.0257 0.0257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0016 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0331 0.0998
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0156 0.0809 0.0809
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.0055 0.0152
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0078 0.0915
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0227 0.0227
Schistosoma mansoni zinc finger protein 0.0074 0.0331 0.0331
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0009 0.0013
Brugia malayi beta-lactamase 0.0149 0.0767 0.0767
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0016 0.0028
Schistosoma mansoni patched 1 0.0041 0.0143 0.0143
Echinococcus multilocularis expressed protein 0.0432 0.2405 0.2405
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.0257 0.2159
Brugia malayi jmjC domain containing protein 0.0018 0.0009 0.0009

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.46 uM Antimalarial activity after 72 hrs against chloroquine-resistant Plasmodium falciparum W2 by Malstat LDH activity ChEMBL. 19574054
IC50 (functional) = 0.5 uM Antimalarial activity after 72 hrs against chloroquine-sensitive Plasmodium falciparum D6 by Malstat LDH activity ChEMBL. 19574054

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23 19574054

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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