Detailed information for compound 106093

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 311.376 | Formula: C22H17NO
  • H donors: 1 H acceptors: 2 LogP: 5.6 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#C/C(=C(/c1ccc(cc1)O)\c1ccc(cc1)C)/c1ccccc1
  • InChi: 1S/C22H17NO/c1-16-7-9-18(10-8-16)22(19-11-13-20(24)14-12-19)21(15-23)17-5-3-2-4-6-17/h2-14,24H,1H3/b22-21-
  • InChiKey: YCHUKCZZGUEKDH-DQRAZIAOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0013 0.1662
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0003 0.001
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0047 0.0035 0.0115
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Onchocerca volvulus 0.0122 0.0117 0.115
Leishmania major histone deacetylase, putative 0.1789 0.1913 0.7513
Entamoeba histolytica cysteine protease, putative 0.0017 0.0003 0.0007
Brugia malayi protein C24B5.3 0.0064 0.0054 0.0207
Brugia malayi Myosin head containing protein 0.0064 0.0054 0.0207
Echinococcus granulosus aldo keto reductase 0.0122 0.0117 0.0388
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.2377 0.2546 1
Leishmania major cathepsin L-like protease 0.0017 0.0003 0.0007
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0014 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Loa Loa (eye worm) ribosomal RNA methyltransferase 0.0016 0.0002 0.0008
Trichomonas vaginalis aldo/keto reductase, putative 0.0122 0.0117 0.0455
Echinococcus granulosus beta LACTamase domain containing family member 0.0229 0.0232 0.0773
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0003 0.001
Schistosoma mansoni cpg binding protein 0.0239 0.0243 0.0807
Entamoeba histolytica hypothetical protein 0.0027 0.0014 0.005
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0078 0.0068 0.0265
Loa Loa (eye worm) glutamate receptor 0.0045 0.0033 0.0129
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0096 0.0088 0.0142
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.002 0.0063
Brugia malayi jmjC domain containing protein 0.0015 0.0001 0.0003
Toxoplasma gondii histone deacetylase HDAC2 0.2068 0.2214 0.8693
Loa Loa (eye worm) hypothetical protein 0.0052 0.0041 0.0161
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trichomonas vaginalis D-aminoacylase, putative 0.0229 0.0232 0.0908
Leishmania major nicotinate phosphoribosyltransferase, putative 0.0066 0.0056 0.0218
Echinococcus granulosus Protein patched homolog 1 0.0452 0.0472 0.1572
Echinococcus granulosus acetylcholinesterase 0.0066 0.0056 0.0187
Echinococcus multilocularis voltage gated potassium channel subunit 0.0122 0.0117 0.0117
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0008 0.0008
Schistosoma mansoni coup transcription factor 0.0054 0.0043 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0113 0.044
Schistosoma mansoni phd finger protein 0.0019 0.0006 0.0016
Schistosoma mansoni neprilysin-2 (M13 family) 0.0048 0.0037 0.0121
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0122 0.0117 0.0452
Loa Loa (eye worm) hypothetical protein 0.1053 0.112 0.4397
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0054 0.0043 0.0167
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0025 0.0012 0.0039
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0145 0.0141 0.0553
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0078 0.0068 0.0101
Mycobacterium tuberculosis Probable lipase LipD 0.0229 0.0232 0.0379
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0022 0.007
Echinococcus granulosus histone deacetylase 6 0.1834 0.1961 0.6536
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0053 0.0042 0.016
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB1 0.0066 0.0056 0.0089
Onchocerca volvulus 0.0032 0.002 0.0187
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0003 0.0003
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0044 0.0032 0.0124
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0025 0.0011 0.0041
Echinococcus granulosus endothelin converting enzyme 1 0.0096 0.0088 0.0294
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0059 0.0048 0.0158
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.002 0.0063
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0054 0.0043 0.0167
Trichomonas vaginalis adenosylhomocysteinase, putative 0.2377 0.2546 1
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0019 0.0005 0.0005
Toxoplasma gondii hypothetical protein 0.0016 0.0002 0.0005
Echinococcus multilocularis disco interacting protein 2 0.0047 0.0035 0.0035
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0042 0.016
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0054 0.0043 0.014
Plasmodium falciparum glutathione reductase 0.0017 0.0003 0.001
Echinococcus multilocularis expressed protein 0.0017 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0032 0.0019 0.0062
Schistosoma mansoni topbp1 0.0032 0.0019 0.0063
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.0002 0.0005
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0068 0.0265
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0217 0.085
Schistosoma mansoni netrin receptor unc5 0.0069 0.0059 0.0195
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0061 0.024
Schistosoma mansoni hypothetical protein 0.0097 0.0089 0.0294
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0053 0.0042 0.016
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0076 0.0066 0.0258
Echinococcus multilocularis aldo keto reductase 0.0122 0.0117 0.0117
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0066 0.0098
Trypanosoma brucei metacaspase MCA3 0.0053 0.0042 0.016
Onchocerca volvulus 0.003 0.0017 0.0157
Trichomonas vaginalis histone deacetylase, putative 0.2068 0.2214 0.8693
Brugia malayi bHLH-PAS transcription factor 0.0044 0.0032 0.0124
Loa Loa (eye worm) histone deacetylase 11 0.1818 0.1944 0.7636
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0003
Schistosoma mansoni adenosylhomocysteinase 0.2377 0.2546 0.8487
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.004 0.0154
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.0002 0.0002
Schistosoma mansoni smad1 5 8 and 0.0016 0.0002 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0217 0.085
Echinococcus granulosus voltage gated potassium channel subunit 0.0122 0.0117 0.0388
Loa Loa (eye worm) hypothetical protein 0.0055 0.0044 0.0172
Onchocerca volvulus 0.0025 0.0012 0.0112
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0048 0.0184
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0035 0.0023 0.0089
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0012 0.0047
Leishmania major DNA damage repair protein, putative 0.003 0.0017 0.0064
Giardia lamblia Kinase, PLK 0.0439 0.0458 0.2068
Echinococcus multilocularis histone deacetylase 6 0.1789 0.1913 0.1913
Toxoplasma gondii aldose reductase, putative 0.0122 0.0117 0.0455
Brugia malayi glutathione reductase 0.0049 0.0038 0.0146
Schistosoma mansoni biogenic amine receptor 0.0032 0.002 0.0063
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0068 0.0101
Echinococcus granulosus metabotropic glutamate receptor 5 0.0055 0.0044 0.0147
Onchocerca volvulus 0.0064 0.0054 0.0524
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0058 0.0047 0.0158
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0113 0.0106 0.0415
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Echinococcus granulosus Protein kinase C brain isozyme 0.0016 0.0002 0.0006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0042 0.016
Echinococcus granulosus Niemann Pick C1 protein 0.1053 0.112 0.3732
Schistosoma mansoni hypothetical protein 0.0097 0.0089 0.0294
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0003 0.0007
Echinococcus granulosus transient receptor potential ion channel A 0.0092 0.0083 0.0278
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0068 0.0109
Echinococcus multilocularis thyroid hormone receptor alpha 0.0054 0.0043 0.0043
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0038 0.0144
Plasmodium falciparum histone deacetylase 2 0.1789 0.1913 0.7513
Loa Loa (eye worm) hypothetical protein 0.0229 0.0232 0.0911
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.002 0.002
Schistosoma mansoni myst-related protein 0.0027 0.0014 0.0043
Trypanosoma brucei metacaspase MCA2 0.0053 0.0042 0.016
Onchocerca volvulus 0.0229 0.0232 0.2296
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0005
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0053 0.0042 0.0162
Trichomonas vaginalis helicase, putative 0.0051 0.004 0.0154
Schistosoma mansoni hypothetical protein 0.0025 0.0012 0.0037
Onchocerca volvulus 0.0064 0.0054 0.0524
Onchocerca volvulus 0.0064 0.0054 0.0524
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0217 0.085
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0122 0.0117 0.0388
Echinococcus granulosus Niemann Pick C1 protein 0.1505 0.1607 0.5355
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.0113 0.044
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0216 0.0217 0.0852
Echinococcus multilocularis cpg binding protein 0.0239 0.0243 0.0243
Echinococcus granulosus aryl hydrocarbon receptor 0.0129 0.0124 0.0412
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0068 0.0101
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0045 0.0034 0.0129
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0076
Giardia lamblia Replication factor C, subunit 1 0.0032 0.002 0.0085
Echinococcus granulosus histone deacetylase 0.1789 0.1913 0.6377
Toxoplasma gondii patched family protein 0.0064 0.0054 0.0207
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0008 0.0029
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0066 0.0066
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0048 0.0075
Echinococcus granulosus dna polymerase eta 0.0116 0.011 0.0367
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0014 0.0052
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0078 0.0068 0.0101
Schistosoma mansoni transient receptor potential channel 4 0.0095 0.0087 0.0287
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0001 0.0001
Echinococcus multilocularis serotonin receptor 0.0152 0.0148 0.0148
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0078 0.0068 0.0109
Loa Loa (eye worm) adenosylhomocysteinase 0.2377 0.2546 1
Plasmodium falciparum aldo-keto reductase, putative 0.0122 0.0117 0.0455
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0097 0.0089 0.0349
Entamoeba histolytica peptidase, C54 family 0.0018 0.0004 0.0012
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0078 0.0068 0.0268
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.004 0.0154
Trypanosoma cruzi metacaspase, putative 0.0053 0.0042 0.016
Echinococcus granulosus tar DNA binding protein 0.0317 0.0326 0.1087
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0053 0.0042 0.0165
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.002 0.0063
Echinococcus granulosus cpg binding protein 0.0239 0.0243 0.0809
Echinococcus multilocularis Niemann Pick C1 protein 0.1053 0.112 0.112
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Brugia malayi polk-prov protein 0.0052 0.0041 0.0158
Onchocerca volvulus Glucosylceramidase homolog 0.0141 0.0137 0.1354
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0012 0.0044
Schistosoma mansoni inositol monophosphatase 0.0076 0.0066 0.0219
Schistosoma mansoni DNA ligase IV 0.0032 0.0019 0.0063
Leishmania major DNA polymerase eta, putative 0.0116 0.011 0.0429
Brugia malayi metabotropic glutamate receptor type 2 0.0022 0.0008 0.0029
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0022 0.0073
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.001
Echinococcus granulosus g protein coupled receptor 0.0032 0.002 0.0065
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0053 0.0042 0.0162
Loa Loa (eye worm) hypothetical protein 0.0066 0.0056 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.004 0.0154
Mycobacterium tuberculosis Conserved hypothetical protein 0.0427 0.0445 0.0731
Brugia malayi Hr1 repeat family protein 0.0015 0.0001 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0068 0.0265
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.1053 0.112 0.4395
Brugia malayi DIX domain containing protein 0.0016 0.0002 0.0005
Onchocerca volvulus Protein ultraspiracle homolog 0.0054 0.0043 0.0416
Onchocerca volvulus 0.0017 0.0003 0.0018
Plasmodium vivax vivapain-2 0.0017 0.0003 0.0007
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.001 0.0031
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.001
Mycobacterium tuberculosis Probable lipase LipE 0.0229 0.0232 0.0379
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.002 0.0065
Trypanosoma cruzi metacaspase, putative 0.0053 0.0042 0.016
Schistosoma mansoni z-protein (S1r protein) 0.0016 0.0002 0.0004
Echinococcus granulosus geminin 0.0647 0.0682 0.2273
Trypanosoma brucei histone deacetylase 3 0.1789 0.1913 0.7513
Brugia malayi neuropeptide F receptor 0.0032 0.002 0.0074
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0035 0.0023 0.0087
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0001 0.0003
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0014 0.0052
Toxoplasma gondii cathepsin CPL 0.0017 0.0003 0.0007
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0001 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0054 0.0043 0.0165
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0111 0.0105 0.0409
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Echinococcus granulosus tumor protein p63 0.2207 0.2363 0.7877
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.002 0.0077
Brugia malayi PHD-finger family protein 0.0025 0.0012 0.0043
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0008 0.0033
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.2068 0.2214 0.8693
Trypanosoma cruzi FHA domain containing protein, putative 0.0032 0.0019 0.0074
Leishmania major hypothetical protein, conserved 0.0044 0.0032 0.0124
Echinococcus multilocularis g protein coupled receptor 0.0032 0.002 0.002
Brugia malayi Cell death protein 3 precursor 0.0053 0.0042 0.016
Giardia lamblia Histone acetyltransferase GCN5 0.0133 0.0128 0.0577
Echinococcus multilocularis ferritin 0.0017 0.0003 0.0003
Echinococcus granulosus fmrfamide receptor 0.0032 0.002 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0439 0.0458 0.1797
Loa Loa (eye worm) ctsf protein 0.0017 0.0003 0.001
Loa Loa (eye worm) histone methyltransferase 0.0072 0.0062 0.0244
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.002 0.0063
Schistosoma mansoni apoferritin-2 0.0017 0.0003 0.0008
Echinococcus multilocularis ribosomal RNA large subunit methyltransferase 0.0016 0.0002 0.0002
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0019 0.0005 0.0016
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.002 0.002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.002 0.0074
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0113 0.0106 0.0172
Trypanosoma cruzi aldo-keto reductase 0.0122 0.0117 0.0455
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0078 0.0068 0.0265
Plasmodium falciparum protoporphyrinogen oxidase 0.0427 0.0445 0.1745
Plasmodium vivax acyl-CoA synthetase, putative 0.0194 0.0193 0.0757
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0306 0.0314 0.1233
Trichomonas vaginalis replication factor C large subunit, putative 0.0032 0.002 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0054 0.0043 0.0165
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Brugia malayi intermediate filament protein 0.003 0.0017 0.0062
Schistosoma mansoni nicotinate phosphoribosyltransferase 0.0066 0.0056 0.0185
Brugia malayi Carboxylesterase family protein 0.0066 0.0056 0.0217
Brugia malayi histone deacetylase 11 0.1818 0.1944 0.7635
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0113 0.044
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0053 0.0042 0.0042
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0202 0.0202 0.079
Schistosoma mansoni dep domain containing protein 0.0016 0.0002 0.0004
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.002 0.0065
Brugia malayi Probable ClpP-like protease 0.0076 0.0066 0.0257
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.0089 0.0089
Entamoeba histolytica hypothetical protein 0.0032 0.0019 0.0074
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0032 0.0019 0.0074
Schistosoma mansoni adenosylhomocysteinase 0.1471 0.157 0.5232
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0062
Echinococcus granulosus NDR protein kinase 0.0015 0.0001 0.0004
Brugia malayi hypothetical protein 0.0064 0.0054 0.0207
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Onchocerca volvulus 0.0122 0.0117 0.115
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0059 0.0048 0.0187
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0122 0.0117 0.0388
Echinococcus multilocularis serine:threonine protein kinase 38 0.0015 0.0001 0.0001
Brugia malayi T-complex protein 1, beta subunit 0.0019 0.0005 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0229 0.0232 0.0908
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.002 0.0187
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0053 0.0042 0.0042
Trypanosoma brucei RNA helicase, putative 0.0114 0.0107 0.0419
Brugia malayi RE15519p 0.0032 0.002 0.0074
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0113 0.044
Schistosoma mansoni cpg binding protein 0.0226 0.0229 0.076
Schistosoma mansoni hypothetical protein 0.0436 0.0454 0.1512
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0058 0.0047 0.0047
Leishmania major 4-coumarate:coa ligase-like protein 0.0258 0.0263 0.1031
Loa Loa (eye worm) hypothetical protein 0.0095 0.0087 0.0341
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0375 0.0389 0.1524
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0043 0.014
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0003 0.001
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0076 0.0066 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.012 0.0194
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Leishmania major pantothenate kinase subunit, putative 0.0025 0.0011 0.0041
Schistosoma mansoni brca1-associated protein (brap2) 0.0044 0.0032 0.0106
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0042 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0035 0.005
Schistosoma mansoni hypothetical protein 0.0032 0.002 0.0063
Schistosoma mansoni cytochrome P450 0.0016 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0003 0.0006
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0078 0.0068 0.0068
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.002 0.0074
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0066 0.0258
Mycobacterium leprae Conserved hypothetical protein 0.0016 0.0002 0.0004
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0045 0.0034 0.0129
Schistosoma mansoni bromodomain containing protein 0.0025 0.0012 0.0037
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0229 0.0232 0.0771
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0005
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0113 0.0107 0.0416
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0746 0.0789 0.3096
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0045 0.0034 0.0129
Leishmania major cytochrome p450-like protein 0.0021 0.0007 0.0025
Mycobacterium ulcerans putative regulatory protein 0.0044 0.0032 0.0046
Brugia malayi hypothetical protein 0.0427 0.0445 0.1745
Loa Loa (eye worm) hypothetical protein 0.0194 0.0193 0.0759
Toxoplasma gondii thioredoxin reductase 0.0049 0.0038 0.0146
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0078 0.0068 0.0101
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0427 0.0445 0.1743
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0014 0.0052
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0016 0.0002 0.0007
Onchocerca volvulus 0.0048 0.0036 0.035
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0038 0.0038
Schistosoma mansoni retinoic acid receptor RXR 0.0054 0.0043 0.014
Mycobacterium ulcerans hypothetical protein 0.0122 0.0117 0.0175
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0017 0.0065
Brugia malayi hypothetical protein 0.0018 0.0004 0.0011
Chlamydia trachomatis DNA ligase 0.0032 0.0019 0.0422
Onchocerca volvulus Protein patched homolog 0.0064 0.0054 0.0524
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0012 0.0012
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0012 0.004
Onchocerca volvulus Histone deacetylase 10 homolog 0.0949 0.1008 1
Echinococcus multilocularis sentrin specific protease 7 0.017 0.0168 0.0168
Brugia malayi Patched related family protein 12 0.0064 0.0054 0.0207
Schistosoma mansoni ap endonuclease 0.0058 0.0048 0.0156
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0054 0.0043 0.0167
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.002 0.0065
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0038 0.0038
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0016 0.0002 0.0006
Loa Loa (eye worm) TAR-binding protein 0.0317 0.0326 0.128
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Echinococcus multilocularis Ankyrin 0.007 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Brugia malayi G-protein coupled receptor 0.0032 0.002 0.0074
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0003 0.001
Echinococcus granulosus death domain containing protein 0.0069 0.0059 0.0198
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0044 0.0032 0.0124
Trichomonas vaginalis beta-galactosidase, putative 0.1437 0.1534 0.6021
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0043 0.0165
Trichomonas vaginalis aldo/keto reductase, putative 0.0122 0.0117 0.0455
Onchocerca volvulus 0.0122 0.0117 0.115
Schistosoma mansoni transient receptor potential channel 0.0063 0.0053 0.0173
Echinococcus multilocularis serine:threonine protein kinase N2 0.0015 0.0001 0.0001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0194 0.0193 0.0293
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0048 0.0184
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.002 0.0065
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0137 0.0536
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0053 0.0042 0.0165
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0045 0.0034 0.011
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0068 0.0263
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0031 0.0018 0.0061
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Schistosoma mansoni autophagin-1 (C54 family) 0.0045 0.0034 0.011
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.002 0.0065
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0427 0.0445 0.1745
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0003 0.001
Plasmodium vivax JmjC domain containing protein 0.0015 0.0001 0.0003
Brugia malayi jmjC domain containing protein 0.0015 0.0001 0.0003
Brugia malayi hypothetical protein 0.0449 0.0469 0.1838
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.012 0.0194
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0439 0.0458 0.1528
Schistosoma mansoni survival motor neuron protein 0.0202 0.0202 0.0671
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0054 0.0043 0.014
Onchocerca volvulus 0.0017 0.0003 0.0018
Echinococcus granulosus Ankyrin 0.007 0.006 0.0199
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0078 0.0068 0.0265
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0137 0.0536
Onchocerca volvulus 0.0032 0.002 0.0187
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0054 0.0043 0.0142
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0047 0.0035 0.0054
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Brugia malayi F/Y-rich N-terminus family protein 0.0071 0.0061 0.0238
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0015 0.0057
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0045 0.0034 0.0129
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0003 0.0007
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0427 0.0445 0.1745
Loa Loa (eye worm) oxidoreductase 0.0122 0.0117 0.0457
Trichomonas vaginalis inositol monophosphatase, putative 0.0076 0.0066 0.0258
Schistosoma mansoni transient receptor potential channel 0.0063 0.0052 0.0172
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0043 0.0165
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.002 0.002
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0122 0.0117 0.0455
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0048 0.7048
Brugia malayi MH1 domain containing protein 0.0016 0.0002 0.0004
Schistosoma mansoni lamin 0.003 0.0017 0.0053
Loa Loa (eye worm) glutaminase 0.0934 0.0991 0.3891
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0044 0.0032 0.0124
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0038 0.0149
Leishmania major cathepsin L-like protease 0.0017 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0015 0.0001 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0014 0.0052
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0058 0.0047 0.0156
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0069 0.0059 0.0059
Schistosoma mansoni hypothetical protein 0.0647 0.0682 0.2271
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0034 0.0134
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0122 0.0117 0.0388
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.002 0.0065
Loa Loa (eye worm) hypothetical protein 0.0258 0.0263 0.1034
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0137 0.0536
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0258 0.0263 0.1029
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0181 0.0709
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0007 0.0028
Plasmodium vivax importin-beta 2, putative 0.0047 0.0035 0.0135
Echinococcus granulosus phd:f box containing protein 0.0015 0.0001 0.0005
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0008 0.0029
Brugia malayi Histone deacetylase family protein 0.1789 0.1913 0.7513
Echinococcus granulosus integrin alpha ps 0.0067 0.0057 0.019
Echinococcus granulosus caspase 8 0.0053 0.0042 0.0138
Loa Loa (eye worm) carboxylesterase 0.0066 0.0056 0.022
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0015 0.0001 0.0004
Echinococcus granulosus short transient receptor potential channel 6 0.0063 0.0053 0.0175
Brugia malayi Phospholipase A2 family protein 0.0071 0.0061 0.0237
Brugia malayi nuclear receptor RXR 0.0025 0.0012 0.0044
Onchocerca volvulus 0.0032 0.002 0.0187
Schistosoma mansoni transcription factor LCR-F1 0.0449 0.0469 0.156
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0001 0.0002
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0017 0.0003 0.0007
Toxoplasma gondii peptidase family M13 protein 0.0096 0.0088 0.0344
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0042 0.016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0054 0.0043 0.0165
Schistosoma mansoni smad1 5 8 and 0.0016 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0054 0.0043 0.0167
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0012 0.0112
Brugia malayi histone deacetylase 1 (HD1) 0.2068 0.2214 0.8693
Brugia malayi beta-lactamase 0.0229 0.0232 0.0908
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0048 0.0186
Leishmania major DNA polymerase kappa, putative 0.003 0.0017 0.0064
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0038 0.0059
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.002 0.0063
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0053 0.0042 0.0162
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0043 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.004 0.0154
Schistosoma mansoni tar DNA-binding protein 0.0317 0.0326 0.1085
Echinococcus granulosus zinc finger protein 0.0025 0.0012 0.0039
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0008 0.0031
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0047 0.0157
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0003 0.001
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0032 0.0019 0.0071
Schistosoma mansoni amine GPCR 0.0032 0.002 0.0063
Echinococcus granulosus protein kinase c epsilon type 0.0016 0.0002 0.0006
Echinococcus multilocularis caspase 8 0.0053 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0258 0.0263 0.1034
Onchocerca volvulus Bile acid receptor homolog 0.0054 0.0043 0.0416
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0884 0.0938 0.3682
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0053 0.0042 0.0162
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.1371 0.1462 0.574
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0072 0.0062 0.0062
Mycobacterium ulcerans esterase/lipase LipP 0.0229 0.0232 0.0352
Echinococcus multilocularis lamin 0.003 0.0017 0.0017
Loa Loa (eye worm) oxidoreductase 0.0078 0.0068 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Trypanosoma cruzi ISWI complex protein 0.0024 0.001 0.0038
Entamoeba histolytica aldose reductase, putative 0.0122 0.0117 0.0455
Brugia malayi Dopamine receptor protein 2 0.0032 0.002 0.0074
Echinococcus multilocularis L aminoadipate semialdehyde 0.0059 0.0048 0.0048
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0008 0.0027
Plasmodium falciparum aldehyde reductase, putative 0.0122 0.0117 0.0455
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0137 0.0536
Schistosoma mansoni cell division protein ftsj 0.0016 0.0002 0.0005
Entamoeba histolytica peptidase, C54 family 0.0018 0.0004 0.0012
Echinococcus multilocularis peregrin 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0068 0.0109
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0439 0.0458 0.18
Schistosoma mansoni ran 0.0022 0.0008 0.0024
Loa Loa (eye worm) zinc metallopeptidase 4 0.0023 0.001 0.0039
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0003 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0003 0.0007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0046 0.0067
Plasmodium falciparum importin beta, putative 0.0047 0.0035 0.0135
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0011
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Echinococcus multilocularis serotonin receptor 0.0152 0.0148 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.004 0.0154
Loa Loa (eye worm) hypothetical protein 0.0054 0.0043 0.0167
Onchocerca volvulus 0.0078 0.0068 0.067
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.002 0.0074
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.002 0.0077
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0053 0.0042 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0002 0.0005
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0306 0.0314 0.1231
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0035 0.005
Echinococcus granulosus short transient receptor potential channel 6 0.0063 0.0052 0.0174
Schistosoma mansoni lamin 0.003 0.0017 0.0053
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0044 0.0032 0.0124
Echinococcus multilocularis sterol regulatory element binding protein 0.0452 0.0472 0.0472
Echinococcus multilocularis short transient receptor potential channel 6 0.0063 0.0052 0.0052
Echinococcus granulosus Pleckstrin G protein interacting region 0.0016 0.0002 0.0007
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.002 0.0065
Echinococcus granulosus smad 0.0016 0.0002 0.0005
Schistosoma mansoni apoferritin-2 0.0017 0.0003 0.0008
Brugia malayi neuropeptide F receptor 0.0032 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0096 0.0088 0.0346
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0042 0.016
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0045 0.0034 0.0129
Onchocerca volvulus 0.003 0.0017 0.0157
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0034 0.0021 0.0078
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0044 0.0032 0.0127
Echinococcus granulosus snurportin 1 0.0499 0.0523 0.1743
Echinococcus multilocularis cysteine protease 0.0017 0.0003 0.0003
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.002 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0017 0.0064
Echinococcus multilocularis aldo keto reductase 0.0122 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.006 0.0049 0.0192
Echinococcus granulosus g-protein coupled receptor 0.0032 0.002 0.0065
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0025 0.0012 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0229 0.0232 0.0908
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0229 0.0232 0.0352
Echinococcus granulosus carboxylesterase 5A 0.0066 0.0056 0.0187
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0076
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0078 0.0068 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0452 0.0472 0.185
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0216 0.0217 0.085
Toxoplasma gondii hypothetical protein 0.0064 0.0054 0.0207
Trypanosoma brucei rac serine-threonine kinase, putative 0.0015 0.0001 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0122 0.0117 0.0388
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Trypanosoma brucei aldo-keto reductase, putative 0.0122 0.0117 0.0455
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0015 0.0001 0.0001
Schistosoma mansoni SET domain protein 0.0031 0.0018 0.0059
Schistosoma mansoni histone deacetylase 0.2068 0.2214 0.7378
Loa Loa (eye worm) hypothetical protein 0.0427 0.0445 0.1747
Loa Loa (eye worm) hypothetical protein 0.0869 0.0921 0.3617
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.002 0.002
Giardia lamblia DINP protein human, muc B family 0.0102 0.0095 0.0425
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0012 0.0038
Echinococcus multilocularis ecdysone induced protein 78C 0.0054 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0042 0.016
Schistosoma mansoni beta-mannosidase 0.0466 0.0487 0.1621
Leishmania major aldo-keto reductase-like protein 0.0122 0.0117 0.0455
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Brugia malayi ImpB/MucB/SamB family protein 0.0097 0.0089 0.0346
Onchocerca volvulus 0.0032 0.002 0.0187
Echinococcus multilocularis muscleblind protein 1 0.015 0.0146 0.0146
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.0019 0.0074
Brugia malayi Pax transcription activation domain interacting protein 0.0032 0.0019 0.0074
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0078 0.0068 0.0265
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0048 0.0184
Brugia malayi Latrophilin receptor protein 2 0.0097 0.0089 0.0346
Plasmodium falciparum zinc finger protein, putative 0.0027 0.0014 0.005
Onchocerca volvulus 0.0064 0.0054 0.0524
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.0002 0.0007
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0042 0.016
Onchocerca volvulus 0.0064 0.0054 0.0524
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0043 0.0142
Echinococcus granulosus hypothetical protein 0.0122 0.0117 0.0388
Echinococcus multilocularis beta LACTamase domain containing family member 0.0229 0.0232 0.0232
Schistosoma mansoni histone deacetylase 0.2068 0.2214 0.7378
Toxoplasma gondii hypothetical protein 0.0026 0.0013 0.0047
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0001 0.0003
Brugia malayi acetyltransferase, GNAT family protein 0.0495 0.0518 0.2031
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0053 0.0204
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0078 0.0068 0.0109
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0048 0.0037 0.0121
Trichomonas vaginalis BRCA1-associated protein, putative 0.0044 0.0032 0.0124
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0048 0.0048
Trichomonas vaginalis glycoside hydrolase, putative 0.1437 0.1534 0.6021
Loa Loa (eye worm) inositol-1 0.0076 0.0066 0.026
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0111 0.0105 0.0409
Echinococcus multilocularis geminin 0.0647 0.0682 0.0682
Entamoeba histolytica serine/threonine protein kinase, putative 0.0439 0.0458 0.1797
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.002 0.0065
Brugia malayi Uncoordinated protein 44 0.0069 0.0059 0.023
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Loa Loa (eye worm) hypothetical protein 0.003 0.0017 0.0065
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0152 0.0148 0.0581
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0037 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Loa Loa (eye worm) DIX domain-containing protein 0.0016 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0015 0.0001 0.0004
Onchocerca volvulus 0.0032 0.002 0.0187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0059 0.023
Brugia malayi ribosomal RNA methyltransferase 0.0016 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0066 0.0258
Schistosoma mansoni amine oxidase 0.0427 0.0445 0.1481
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0001 0.0002
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.002 0.0074
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0017 0.0064
Brugia malayi Pre-SET motif family protein 0.0207 0.0208 0.0813
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0113 0.0106 0.0172
Trypanosoma brucei trypanothione reductase 0.0049 0.0038 0.0146
Trypanosoma cruzi DNA polymerase eta, putative 0.0116 0.011 0.0429
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0122 0.0117 0.0455
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0038 0.0146
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0003 0.0003
Loa Loa (eye worm) patched family protein 0.0064 0.0054 0.021
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.0002 0.0007
Loa Loa (eye worm) integrin alpha pat-2 0.023 0.0233 0.0915
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.0002 0.0002
Brugia malayi ecdysteroid receptor 0.0054 0.0043 0.0165
Plasmodium vivax histone deacetylase 1, putative 0.2068 0.2214 0.8693
Giardia lamblia FtsJ cell division protein, putative 0.0016 0.0002 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0043 0.0165
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0078 0.0068 0.0265
Entamoeba histolytica alcohol dehydrogenase, putative 0.0122 0.0117 0.0455
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0002 0.0007
Loa Loa (eye worm) AGC/PKN protein kinase 0.0015 0.0001 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0439 0.0458 0.1797
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0057 0.0046 0.0073
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.001
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0269 0.0274 0.1077
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0025 0.0012 0.0012
Toxoplasma gondii patched family protein 0.0064 0.0054 0.0207
Schistosoma mansoni aldo-keto reductase 0.0122 0.0117 0.0386
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0019 0.0005 0.0016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0097 0.0089 0.0089
Echinococcus granulosus survival motor neuron protein 1 0.0988 0.105 0.3499
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0017 0.0064
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0076 0.0066 0.0258
Brugia malayi jmjC domain containing protein 0.0015 0.0001 0.0003
Leishmania major histone deacetylase, putative 0.1789 0.1913 0.7513
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.002 0.0063
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0194 0.0193 0.4338
Plasmodium vivax acetyl-CoA synthetase, putative 0.0078 0.0068 0.0265
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.002 0.0077
Plasmodium vivax aldehyde reductase, putative 0.0122 0.0117 0.0455
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.001 0.0038
Mycobacterium leprae Probable lipase LipE 0.0229 0.0232 0.0906
Brugia malayi Cytochrome P450 family protein 0.0046 0.0034 0.0132
Loa Loa (eye worm) hypothetical protein 0.0209 0.021 0.0824
Echinococcus multilocularis rrna methyltransferase 3 0.0016 0.0002 0.0002
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0054 0.0043 0.014
Brugia malayi AMP-binding enzyme family protein 0.0258 0.0263 0.1031
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0247
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0122 0.0117 0.0457
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0019 0.0005 0.0016
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0053 0.0042 0.014
Loa Loa (eye worm) hypothetical protein 0.0229 0.0232 0.0911
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0047 0.0035 0.0054
Plasmodium vivax histone deacetylase, putative 0.1789 0.1913 0.7513
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0043 0.0165
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0003 0.0018
Schistosoma mansoni biogenic amine receptor 0.0032 0.002 0.0063
Brugia malayi Cytochrome P450 family protein 0.0021 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0003 0.0007
Loa Loa (eye worm) cytochrome P450 0.0016 0.0002 0.0009
Plasmodium vivax histone deacetylase 2, putative 0.1789 0.1913 0.7513
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0017 0.0064
Trypanosoma cruzi histone deacetylase, putative 0.0949 0.1008 0.3957
Brugia malayi Peptidase family C54 containing protein 0.0045 0.0034 0.0129
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0035 0.0133
Echinococcus granulosus histone acetyltransferase KAT2B 0.0481 0.0503 0.1676
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0439 0.0458 0.1797
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.002 0.0063
Plasmodium falciparum ribosomal RNA methyltransferase, putative 0.0016 0.0002 0.0005
Brugia malayi MH2 domain containing protein 0.0016 0.0002 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0113 0.044
Brugia malayi protein C24B5.3 0.0064 0.0054 0.0207
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0066 0.0056 0.0184
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.002 0.0065
Schistosoma mansoni neuropeptide receptor 0.0032 0.002 0.0063
Trichomonas vaginalis nicotinate phosphoribosyltransferase, putative 0.0066 0.0056 0.0218
Brugia malayi Cathepsin L-like precursor 0.0017 0.0003 0.0007
Trypanosoma brucei histone deacetylase, putative 0.1789 0.1913 0.7513
Leishmania major acetyl-CoA synthetase, putative 0.0078 0.0068 0.0265
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.006
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trypanosoma brucei importin beta-1 subunit, putative 0.0047 0.0035 0.0135
Schistosoma mansoni serine/threonine protein kinase 0.0439 0.0458 0.1525
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.002 0.002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0449 0.0469 0.1562
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0122 0.0117 0.0455
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0032 0.002 0.0063
Onchocerca volvulus 0.0078 0.0068 0.067
Onchocerca volvulus 0.0032 0.002 0.0187
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0008 0.0029
Echinococcus multilocularis orexin receptor type 2 0.0032 0.002 0.002
Echinococcus multilocularis neuropeptide receptor 0.0032 0.002 0.002
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0019 0.0005 0.0014
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0012 0.004
Leishmania major S-adenosylhomocysteine hydrolase 0.2377 0.2546 1
Giardia lamblia Aldose reductase 0.0122 0.0117 0.0523
Toxoplasma gondii ATPase, AAA family protein 0.0032 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0053 0.0042 0.0162
Brugia malayi Thioredoxin reductase 0.0049 0.0038 0.0146
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0047 0.0047
Schistosoma mansoni patched 1 0.0452 0.0472 0.157
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0008
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.002 0.002
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0076
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.004 0.0154
Onchocerca volvulus 0.0128 0.0123 0.1215
Schistosoma mansoni hypothetical protein 0.0436 0.0454 0.1512
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.002 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0019 0.0074
Echinococcus multilocularis histone deacetylase 6 0.1834 0.1961 0.1961
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0003 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0088 0.0292
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0087
Schistosoma mansoni adenosylhomocysteinase 0.1471 0.157 0.5232
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0012 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0181 0.018 0.0293
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.002 0.002
Echinococcus multilocularis neuropeptide receptor A26 0.0519 0.0544 0.0544
Brugia malayi T-complex protein 1, beta subunit 0.0019 0.0005 0.0016
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0003 0.001
Plasmodium falciparum histone acetyltransferase GCN5 0.0133 0.0128 0.0502
Echinococcus granulosus sex peptide receptor 0.0032 0.002 0.0065
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0037 0.0025 0.0025
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0076 0.0066 0.0098
Brugia malayi hypothetical protein 0.0064 0.0054 0.0207
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.2377 0.2546 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0066 0.0257
Echinococcus granulosus muscleblind protein 0.015 0.0146 0.0486
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0078 0.0068 0.0265
Echinococcus multilocularis neuropeptide s receptor 0.0519 0.0544 0.0544
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0019 0.0005 0.0014
Brugia malayi Histone deacetylase family protein 0.1789 0.1913 0.7513
Echinococcus multilocularis cysteine protease atg4b 0.0045 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0449 0.0469 0.156
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0082 0.0074 0.0289
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.2377 0.2546 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0066 0.9962
Trypanosoma cruzi histone deacetylase, putative 0.1789 0.1913 0.7513
Entamoeba histolytica hypothetical protein 0.0449 0.0469 0.1838
Loa Loa (eye worm) hypothetical protein 0.0048 0.0036 0.0141
Echinococcus multilocularis transient receptor potential ion channel A 0.0092 0.0083 0.0083
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0007 0.0028
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Entamoeba histolytica acyl-coA synthetase, putative 0.0258 0.0263 0.1031
Brugia malayi Variant SH3 domain containing protein 0.0093 0.0085 0.0331
Mycobacterium ulcerans glutaminase 0.0934 0.0991 0.1516
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0002 0.0006
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Loa Loa (eye worm) hypothetical protein 0.0427 0.0445 0.1747
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0003 0.0001
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0046
Brugia malayi hypothetical protein 0.0988 0.105 0.4121
Loa Loa (eye worm) glycosyl hydrolase family 2 0.1371 0.1462 0.5741
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.004 0.0154
Brugia malayi Calcitonin receptor-like protein seb-1 0.0306 0.0314 0.1231
Loa Loa (eye worm) patched family protein 0.0064 0.0054 0.021
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB2 0.0066 0.0056 0.0089
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0229 0.0232 0.0379
Brugia malayi Protein kinase domain containing protein 0.0071 0.0061 0.0238
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0053 0.0204
Echinococcus granulosus biogenic amine 5HT receptor 0.0152 0.0148 0.0493
Plasmodium vivax FtsJ-like methyltransferase, putative 0.0016 0.0002 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.004 0.0154
Trypanosoma cruzi histone deacetylase, putative 0.1789 0.1913 0.7513
Toxoplasma gondii ribosomal RNA large subunit methyltransferase J protein 0.0016 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0004
Entamoeba histolytica acetyltransferase, GNAT family 0.0133 0.0128 0.0502
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0012 0.0044
Brugia malayi histone deacetylase 3 (HD3) 0.2068 0.2214 0.8693
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0048 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0054 0.0043 0.0165
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0002 0.0003
Echinococcus multilocularis dna polymerase kappa 0.0119 0.0113 0.0113
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0017 0.0003 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Echinococcus granulosus inositol monophosphatase 1 0.0076 0.0066 0.0221
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Echinococcus multilocularis transfer RNA-Lys 0.0044 0.0032 0.0032
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.0089 0.0089
Mycobacterium tuberculosis Conserved protein 0.0229 0.0232 0.0379
Brugia malayi nuclear receptor RXR 0.0028 0.0015 0.0057
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0015 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.0002 0.0002
Echinococcus granulosus intermediate filament protein 0.003 0.0017 0.0055
Trichomonas vaginalis bromodomain-containing protein, putative 0.0145 0.0141 0.0553
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0057 0.0046 0.0179
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Loa Loa (eye worm) hypothetical protein 0.0054 0.0043 0.0167
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Echinococcus granulosus expressed conserved protein 0.0989 0.1051 0.3503
Loa Loa (eye worm) fibroinase 0.0017 0.0003 0.001
Brugia malayi Smad1 0.0016 0.0002 0.0004
Mycobacterium ulcerans lipase LipD 0.0229 0.0232 0.0352
Loa Loa (eye worm) glutaminase 2 0.0934 0.0991 0.3891
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0003 0.0007
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0145 0.0141 0.0553
Leishmania major cathepsin L-like protease 0.0017 0.0003 0.0007
Trypanosoma cruzi metacaspase, putative 0.0053 0.0042 0.016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Echinococcus granulosus allatostatin A receptor 0.0032 0.002 0.0065
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Trichomonas vaginalis DNA polymerase eta, putative 0.0119 0.0113 0.044
Schistosoma mansoni ap endonuclease 0.0058 0.0048 0.0156
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.004 0.0154
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0017 0.0054
Echinococcus granulosus nicotinamide phosphoribosyltransferase 0.0358 0.0371 0.1236
Echinococcus granulosus nibrin 0.0032 0.0019 0.0065
Schistosoma mansoni neuropeptide receptor 0.0032 0.002 0.0063
Schistosoma mansoni hypothetical protein 0.0025 0.0012 0.0037
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0032 0.0019 0.2652
Schistosoma mansoni tar DNA-binding protein 0.0317 0.0326 0.1085
Trichomonas vaginalis histone deacetylase, putative 0.2068 0.2214 0.8693
Schistosoma mansoni metabotropic glutamate receptor 0.0037 0.0025 0.0081
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0045 0.0034 0.0129
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0053 0.0042 0.0165
Echinococcus multilocularis integrin alpha ps 0.0067 0.0057 0.0057
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0054 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Brugia malayi ORL1-like opioid receptor 0.0032 0.002 0.0074
Echinococcus granulosus nuclear factor of activated T cells 5 0.0677 0.0715 0.2382
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0053 0.0042 0.0162
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0046 0.0154
Toxoplasma gondii histone deacetylase HDAC1 0.1789 0.1913 0.7513
Echinococcus granulosus caspase 2 0.0053 0.0042 0.0138
Brugia malayi Cytochrome P450 family protein 0.0021 0.0007 0.0025
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.0089 0.0346
Schistosoma mansoni bromodomain containing protein 0.0025 0.0012 0.0037
Echinococcus multilocularis BRCA1 associated protein 0.0044 0.0032 0.0032
Plasmodium falciparum T-complex protein 1 subunit beta 0.0019 0.0005 0.0016
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0258 0.0263 0.04
Entamoeba histolytica peptidase, C54 family 0.0018 0.0004 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0113 0.044
Trichomonas vaginalis brca1-associated protein, putative 0.0044 0.0032 0.0124
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0003 0.0007
Schistosoma mansoni cpg binding protein 0.0239 0.0243 0.0807
Mycobacterium ulcerans hypothetical protein 0.003 0.0017 0.0023
Onchocerca volvulus Protein patched homolog 0.0064 0.0054 0.0524
Echinococcus multilocularis FTZ F1 alpha 0.0054 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0054 0.0043 0.0167
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0122 0.0117 0.0455
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0023 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Echinococcus multilocularis smad 0.0016 0.0002 0.0002
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0054 0.0043 0.0142
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Mycobacterium tuberculosis Conserved hypothetical protein 0.0417 0.0434 0.0713
Echinococcus granulosus histone deacetylase 7 0.1789 0.1913 0.6377
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.002 0.0077
Plasmodium vivax histone deacetylase, putative 0.1818 0.1944 0.7635
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0401 0.0417 0.0417
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.002 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0113 0.044
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0439 0.0458 0.0458
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0078 0.0068 0.0101
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0003 0.001
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Schistosoma mansoni atypical protein kinase C 0.0015 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0042 0.016
Loa Loa (eye worm) oxidoreductase 0.0122 0.0117 0.0457
Onchocerca volvulus 0.0323 0.0333 0.3298
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0002 0.0005
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0096 0.0088 0.0346
Onchocerca volvulus 0.0085 0.0077 0.0754
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0038 0.0127
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0068 0.0265
Loa Loa (eye worm) hypothetical protein 0.0306 0.0314 0.1233
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0053 0.0042 0.0162
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Echinococcus multilocularis histone deacetylase 3 0.2068 0.2214 0.2214
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0003 0.0003
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.0002 0.0002
Trypanosoma cruzi nicotinate phosphoribosyltransferase, putative 0.0066 0.0056 0.0218
Schistosoma mansoni RAR-like nuclear receptor 0.0054 0.0043 0.014
Schistosoma mansoni histone deacetylase hda2 0.0949 0.1008 0.3358
Brugia malayi G-protein coupled receptor 0.0032 0.002 0.0074
Onchocerca volvulus 0.0045 0.0033 0.0319
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0054 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0016 0.0002 0.0005
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0145 0.0141 0.0553
Entamoeba histolytica hypothetical protein 0.0449 0.0469 0.1838
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0031 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.0449 0.0469 0.1838
Trypanosoma brucei DNA polymerase eta, putative 0.0116 0.011 0.0429
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0043 0.0142
Trypanosoma cruzi histone deacetylase 1, putative 0.2068 0.2214 0.8693
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0046
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0072 0.0062 0.0208
Schistosoma mansoni biogenic amine receptor 0.0032 0.002 0.0063
Echinococcus granulosus expressed protein 0.0017 0.0003 0.001
Trichomonas vaginalis conserved hypothetical protein 0.1437 0.1534 0.6021
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0043 0.014
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0011
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0122 0.0117 0.0455
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.2068 0.2214 0.8693
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.2068 0.2214 0.8693
Brugia malayi Niemann-Pick C1 protein precursor 0.1053 0.112 0.4395
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Echinococcus granulosus protein kinase C gamma type 0.0016 0.0002 0.0006
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0003 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0062 0.0243
Brugia malayi jmjC domain containing protein 0.0058 0.0047 0.0183
Onchocerca volvulus 0.0122 0.0117 0.115
Loa Loa (eye worm) hypothetical protein 0.0554 0.0581 0.2283
Echinococcus multilocularis transient receptor potential gamma protein 0.0095 0.0087 0.0087
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0096 0.0088 0.0347
Echinococcus granulosus sentrin specific protease 8 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Echinococcus multilocularis protein kinase c iota type 0.0015 0.0001 0.0001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0062 0.0243
Echinococcus granulosus aldo keto reductase 0.0122 0.0117 0.0388
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0001 0.0005
Brugia malayi hypothetical protein 0.0025 0.0012 0.0044
Loa Loa (eye worm) hypothetical protein 0.0113 0.0107 0.0418
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.002 0.0063
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0018 0.0004 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0113 0.044
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0045 0.0034 0.011
Trichomonas vaginalis glutaminase, putative 0.0934 0.0991 0.389
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0042 0.016
Echinococcus granulosus TRP transient receptor potential channel 0.0035 0.0023 0.0076
Plasmodium vivax vivapain-2 0.0017 0.0003 0.0007
Brugia malayi sulfakinin receptor protein 0.0032 0.002 0.0074
Onchocerca volvulus 0.0064 0.0054 0.0524
Brugia malayi GnHR receptor homolog 0.0032 0.002 0.0074
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.002 0.0065
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0111 0.0105 0.0409
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0003 0.0007
Brugia malayi nuclear hormone receptor 0.0025 0.0012 0.0044
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0102 0.0095 0.0153
Onchocerca volvulus 0.0258 0.0263 0.2606
Toxoplasma gondii histone deacetylase HDAC3 0.2068 0.2214 0.8693
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.0019 0.0074
Echinococcus granulosus netrin receptor unc 5 0.0069 0.0059 0.0198
Onchocerca volvulus 0.0229 0.0232 0.2296
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.2377 0.2546 0.3903
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0122 0.0117 0.0455
Echinococcus multilocularis protoporphyrinogen oxidase 0.0427 0.0445 0.0445
Trichomonas vaginalis CAMK family protein kinase 0.0439 0.0458 0.1797
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.0089 0.0349
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0014 0.0054
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0012 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0032 0.002 0.0063
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0048 0.0184
Brugia malayi MH1 domain containing protein 0.0016 0.0002 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0054 0.0043 0.0167
Toxoplasma gondii propionate-CoA ligase 0.0078 0.0068 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.004 0.0154
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Loa Loa (eye worm) AGC/AKT protein kinase 0.0015 0.0001 0.0004
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.0002 0.0007
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0048 0.0037 0.0121
Brugia malayi hypothetical protein 0.0027 0.0014 0.0052
Schistosoma mansoni ran 0.0022 0.0008 0.0024
Schistosoma mansoni dishevelled 0.0016 0.0002 0.0004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0058 0.0047 0.0047
Schistosoma mansoni SET domain protein 0.0027 0.0014 0.0044
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0016 0.0001 0.0003
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0001 0.0003
Treponema pallidum DNA ligase (lig) 0.0032 0.0019 0.2713
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0068 0.0058 0.0092
Entamoeba histolytica deoxycytidyl transferase, putative 0.0097 0.0089 0.0346
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0066 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0032 0.002 0.0074
Loa Loa (eye worm) histone deacetylase 1 0.2068 0.2214 0.8694
Onchocerca volvulus 0.0032 0.0019 0.0186
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0047 0.0035 0.0133
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0008 0.0029
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Mycobacterium tuberculosis Probable hydrolase 0.0229 0.0232 0.0379
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0003 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0003 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0258 0.0263 0.04
Entamoeba histolytica peptidase, C54 family 0.0018 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0076
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0015 0.0015
Brugia malayi ImpB/MucB/SamB family protein 0.0116 0.011 0.0429
Mycobacterium ulcerans oxidoreductase 0.0427 0.0445 0.0679
Brugia malayi hypothetical protein 0.0032 0.0019 0.0074
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.002 0.0074
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Trichomonas vaginalis D-aminoacylase, putative 0.0229 0.0232 0.0908
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0677 0.0715 0.0715
Trichomonas vaginalis set domain proteins, putative 0.0235 0.0238 0.093
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0007 0.0007
Loa Loa (eye worm) cysteine protease 0.0017 0.0003 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0068 0.0101
Echinococcus granulosus tm gpcr rhodopsin 0.0843 0.0893 0.2976
Schistosoma mansoni hypothetical protein 0.0025 0.0012 0.0037
Schistosoma mansoni adenosylhomocysteinase 0.1471 0.157 0.5232
Leishmania major cathepsin L-like protease 0.0063 0.0053 0.0204
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0057 0.0046 0.0067
Plasmodium falciparum metacaspase-like protein 0.0053 0.0042 0.016
Brugia malayi nuclear hormone receptor 0.0054 0.0043 0.0165
Onchocerca volvulus 0.0025 0.0012 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Loa Loa (eye worm) hypothetical protein 0.0113 0.0107 0.042
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Echinococcus granulosus orexin receptor type 2 0.0032 0.002 0.0065
Brugia malayi rRNA methyltransferase 0.0016 0.0002 0.0005
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0002 0.0006
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.0002 0.0008
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0003 0.0011
Trypanosoma cruzi DNA polymerase eta, putative 0.005 0.0038 0.0147
Loa Loa (eye worm) hypothetical protein 0.0229 0.0232 0.0911
Brugia malayi Beta-glucuronidase precursor 0.1332 0.142 0.5575
Schistosoma mansoni amine oxidase 0.0427 0.0445 0.1481
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.002 0.0063
Trypanosoma cruzi histone deacetylase 1, putative 0.2068 0.2214 0.8693
Loa Loa (eye worm) hypothetical protein 0.0326 0.0336 0.1318
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0041 0.0158
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0326 0.0336 0.3325
Schistosoma mansoni histone deacetylase 1 2 3 0.0949 0.1008 0.3358
Mycobacterium tuberculosis Probable dehydrogenase 0.0113 0.0106 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Trypanosoma brucei histone deacetylase 1 0.2068 0.2214 0.8693
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0078 0.0068 0.0263
Brugia malayi Patched related family protein 4 0.0064 0.0054 0.0207
Echinococcus granulosus cathepsin l1 0.0017 0.0003 0.0009
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0003 0.0006
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0047 0.0047
Toxoplasma gondii AGC kinase 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0076
Schistosoma mansoni neuropeptide receptor 0.0032 0.002 0.0063
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0048 0.0184
Echinococcus granulosus lamin dm0 0.003 0.0017 0.0055
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0032 0.0019 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0217 0.085
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0054 0.0043 0.0167
Brugia malayi hypothetical protein 0.0064 0.0054 0.0207
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0013 0.0045
Brugia malayi Melatonin receptor type 1A 0.0032 0.002 0.0074
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0449 0.0469 0.0469
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0047 0.0155
Schistosoma mansoni ferritin 0.0017 0.0003 0.0008
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0017 0.0064
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Brugia malayi photoreceptor-specific nuclear receptor 0.0054 0.0043 0.0165
Mycobacterium tuberculosis Possible oxidoreductase 0.0427 0.0445 0.0731
Plasmodium falciparum cysteine protease ATG4, putative 0.0018 0.0004 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0007 0.0028
Echinococcus multilocularis muscleblind protein 0.015 0.0146 0.0146
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0061 0.0204
Loa Loa (eye worm) hypothetical protein 0.0128 0.0123 0.0483
Schistosoma mansoni dishevelled 0.0016 0.0002 0.0004
Echinococcus multilocularis somatostatin receptor 0.0032 0.002 0.002
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.002 0.0065
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.002 0.002
Entamoeba histolytica adenosylhomocysteinase, putative 0.2377 0.2546 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0032 0.0019 0.0074
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0078 0.0068 0.0109
Schistosoma mansoni terminal deoxycytidyl transferase 0.0097 0.0089 0.0294
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0017 0.0064
Echinococcus granulosus dna polymerase kappa 0.0119 0.0113 0.0376
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0217 0.085
Loa Loa (eye worm) glutathione reductase 0.0049 0.0038 0.0149
Onchocerca volvulus 0.0078 0.0068 0.067
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0247
Leishmania major importin beta-1 subunit, putative 0.0038 0.0026 0.0098
Echinococcus multilocularis 0.0016 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0001 0.0003
Trypanosoma brucei ISWI complex protein 0.0024 0.001 0.0038
Leishmania major 4-coumarate:coa ligase-like protein 0.0258 0.0263 0.1031
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0234
Toxoplasma gondii histone deacetylase HDAC4 0.1818 0.1944 0.7635
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0001 0.0003
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0002
Brugia malayi conserved hypotetical protein 0.0025 0.0012 0.0044
Schistosoma mansoni topbp1 0.0032 0.0019 0.0063
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0053 0.0042 0.0162
Leishmania major acetyl-CoA synthetase, putative 0.0078 0.0068 0.0265
Loa Loa (eye worm) hypothetical protein 0.0427 0.0445 0.1747
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0194 0.0193 0.0759
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.2377 0.2546 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0003 0.001
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0096 0.0088 0.0344
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.002 0.0065
Toxoplasma gondii ABC1 family protein 0.0229 0.0232 0.0908
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0078 0.0068 0.0109
Onchocerca volvulus 0.0032 0.002 0.0187
Trichomonas vaginalis histone deacetylase, putative 0.2068 0.2214 0.8693
Mycobacterium ulcerans zinc metalloprotease 0.0096 0.0088 0.0132
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0028 0.0015 0.0051
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0069 0.0059 0.0198
Trypanosoma brucei nicotinate phosphoribosyltransferase, putative 0.0066 0.0056 0.0218
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0047 0.0035 0.0133
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0792 0.0839 0.3291
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0066 0.0254
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0113 0.044
Brugia malayi Pre-SET motif family protein 0.0035 0.0022 0.0084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0003
Onchocerca volvulus 0.0032 0.002 0.0187
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0032 0.002 0.0074
Echinococcus granulosus replication factor c subunit 1 0.0032 0.002 0.0065
Toxoplasma gondii hypothetical protein 0.0128 0.0122 0.0478
Plasmodium vivax SET domain containing protein 0.0019 0.0005 0.0017
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0122 0.0117 0.0388
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0012 0.0038
Onchocerca volvulus 0.0226 0.0229 0.2264
Trichomonas vaginalis adenosylhomocysteinase, putative 0.2377 0.2546 1
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0016 0.0002 0.0006
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0007 0.0025
Brugia malayi tailless protein 0.0025 0.0012 0.0044
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0053 0.0204
Echinococcus granulosus metabotropic glutamate receptor 2 0.0037 0.0025 0.0083
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0229 0.0232 0.0911
Brugia malayi Bromodomain containing protein 0.0025 0.0012 0.0043
Brugia malayi Histone deacetylase 1 0.2068 0.2214 0.8693
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Onchocerca volvulus 0.0032 0.002 0.0187
Echinococcus multilocularis aryl hydrocarbon receptor 0.0129 0.0124 0.0124
Schistosoma mansoni acetyl-CoA synthetase 0.0078 0.0068 0.0225
Brugia malayi SET domain containing protein 0.002 0.0006 0.0021
Mycobacterium ulcerans dehydrogenase 0.0427 0.0445 0.0679
Entamoeba histolytica peptidase, C54 family 0.0045 0.0034 0.0129
Schistosoma mansoni hypothetical protein 0.0025 0.0012 0.0037
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0247
Brugia malayi Cathepsin L-like precursor 0.0017 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.006
Echinococcus granulosus caspase 3 0.0084 0.0075 0.025
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0495 0.0518 0.0518
Onchocerca volvulus Cell death protein 3 homolog 0.0053 0.0042 0.0405
Trichomonas vaginalis CAMK family protein kinase 0.0218 0.0219 0.0859
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0141 0.0472
Brugia malayi Peptidase family M13 containing protein 0.0096 0.0088 0.0344
Toxoplasma gondii t-complex protein beta subunit 0.0019 0.0005 0.0016
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0093 0.0085 0.0334
Schistosoma mansoni tar DNA-binding protein 0.0317 0.0326 0.1085
Mycobacterium ulcerans DNA polymerase IV 0.0119 0.0113 0.0169
Plasmodium falciparum metacaspase 1 0.0053 0.0042 0.016
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.0002 0.0005
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0047 0.0181
Schistosoma mansoni hypothetical protein 0.0025 0.0012 0.0037
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Brugia malayi Serotonin receptor 0.0032 0.002 0.0074
Brugia malayi BRCA1-associated protein 2 containing protein 0.0044 0.0032 0.0124
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0003 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0113 0.044
Plasmodium vivax ribosomal RNA large subunit methyltransferase J, putative 0.0016 0.0002 0.0005
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.002 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0001 0.0003
Plasmodium falciparum lipid/sterol:H+ symporter 0.0064 0.0054 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0117 0.0455
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.002 0.002
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.2377 0.2546 1
Echinococcus multilocularis neuropeptide receptor 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0053 0.0204
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0054 0.0043 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0113 0.044
Chlamydia trachomatis protoporphyrinogen oxidase 0.0427 0.0445 1
Brugia malayi beta-lactamase family protein 0.0229 0.0232 0.0908
Leishmania major trypanothione reductase 0.0049 0.0038 0.0146
Echinococcus multilocularis integrin alpha 3 0.0115 0.0108 0.0108
Schistosoma mansoni smad1 5 8 and 0.0016 0.0002 0.0003
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0003
Loa Loa (eye worm) patched family protein 0.0064 0.0054 0.021
Trichomonas vaginalis ribosomal RNA methyltransferase, putative 0.0016 0.0002 0.0005
Brugia malayi MH2 domain containing protein 0.0016 0.0002 0.0004
Echinococcus multilocularis 0.0427 0.0445 0.0445
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Leishmania major hypothetical protein, conserved 0.0027 0.0014 0.0052
Schistosoma mansoni neprilysin 0.0025 0.0012 0.0037
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0122 0.0117 0.0455
Leishmania major protein kinase, putative 0.0024 0.0011 0.004
Loa Loa (eye worm) hypothetical protein 0.0059 0.0048 0.0189
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Schistosoma mansoni hypothetical protein 0.0097 0.0089 0.0294
Mycobacterium leprae probable zinc metalloprotease 0.0096 0.0088 0.0341
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0048 0.0184
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.002 0.002
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0016 0.0002 0.0008
Plasmodium falciparum histone deacetylase, putative 0.1789 0.1913 0.7513
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0003 0.0007
Brugia malayi CXXC zinc finger family protein 0.0226 0.0229 0.0896
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0042 0.016
Brugia malayi AMP-binding enzyme family protein 0.0258 0.0263 0.1031
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0002
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0229 0.0232 0.0908
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0053 0.0042 0.0138
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0003 0.0009
Brugia malayi jmjC domain containing protein 0.0015 0.0001 0.0003
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0258 0.0263 0.04
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0053 0.0042 0.0162
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0038 0.0059
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0078 0.0068 0.0101
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.002 0.002
Trypanosoma brucei prostaglandin f synthase 0.0122 0.0117 0.0455
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0008 0.0029
Onchocerca volvulus 0.0032 0.002 0.0187
Leishmania major mitochondrial DNA polymerase beta 0.0792 0.0839 0.3291
Toxoplasma gondii histone lysine methyltransferase SET1 0.0443 0.0462 0.1813
Plasmodium vivax hypothetical protein, conserved 0.0427 0.0445 0.1745
Trichomonas vaginalis chaperonin, putative 0.0019 0.0005 0.0016
Echinococcus granulosus hypothetical protein 0.0032 0.002 0.0065
Loa Loa (eye worm) histone deacetylase 0.1789 0.1913 0.7513
Echinococcus granulosus neuropeptide receptor 0.0032 0.002 0.0065
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0122 0.0117 0.0455
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0137 0.0536
Plasmodium vivax hypothetical protein, conserved 0.0229 0.0232 0.0908
Onchocerca volvulus 0.0016 0.0002 0.0012
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.0089 0.0296
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0066 0.0257
Trypanosoma brucei importin beta-1 subunit, putative 0.0047 0.0035 0.0135
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Schistosoma mansoni serine/threonine kinase 0.0015 0.0001 0.0001
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0122 0.0117 0.0388
Echinococcus multilocularis endothelin converting enzyme 1 0.0096 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0202 0.0202 0.0671
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0066 0.0258
Leishmania major DNA polymerase eta, putative 0.005 0.0038 0.0147
Echinococcus multilocularis inositol monophosphatase 1 0.0076 0.0066 0.0066
Schistosoma mansoni inositol monophosphatase 0.0076 0.0066 0.0219
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0019 0.0005 0.0016
Mycobacterium ulcerans hypothetical protein 0.0229 0.0232 0.0352
Schistosoma mansoni opsin-like receptor 0.0032 0.002 0.0063
Trypanosoma brucei DNA polymerase IV, putative 0.0113 0.0107 0.0417
Trypanosoma cruzi importin beta-1 subunit, putative 0.0038 0.0026 0.0098
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Mycobacterium leprae conserved hypothetical protein 0.0229 0.0232 0.0906
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0113 0.0106 0.0412
Onchocerca volvulus 0.0032 0.002 0.0187
Schistosoma mansoni chromosome transmission fidelity factor 0.0032 0.002 0.0063
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0229 0.0232 0.0911
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0054 0.0043 0.0043
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0145 0.0141 0.0553
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0181 0.018 0.0293
Echinococcus granulosus lamin 0.003 0.0017 0.0055
Brugia malayi protein kinase C II. 0.0016 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.0163
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0136 0.0131 0.0512
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.002 0.0065
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Schistosoma mansoni myosin xvIII 0.0032 0.002 0.0063
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0000072961 0.0000072961
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) 0.0047 0.0035 0.0054
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0003 0.0006
Trichomonas vaginalis histone deacetylase, putative 0.2068 0.2214 0.8693
Echinococcus multilocularis survival motor neuron protein 1 0.0988 0.105 0.105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0003 0.0007
Brugia malayi DKFZp564C0469 protein 0.0032 0.0019 0.0074
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0017 0.0064
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0035 0.005
Echinococcus granulosus peregrin 0.0019 0.0006 0.0019
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0096 0.0088 0.0295
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0005
Giardia lamblia TCP-1 chaperonin subunit beta 0.0019 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.015 0.0146 0.0573
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.0002 0.0007
Brugia malayi Cathepsin L-like precursor 0.0017 0.0003 0.0007
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0065 0.0054 0.0086
Brugia malayi STAT protein, DNA binding domain containing protein 0.0158 0.0155 0.0605
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0071 0.0061 0.024
Schistosoma mansoni brca1-associated protein (brap2) 0.0044 0.0032 0.0106
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Brugia malayi steroid hormone receptor 0.0054 0.0043 0.0165
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0003 0.0001
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0016 0.0002 0.0004
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0048 0.0184
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0017 0.0062
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0012 0.004
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.5637 0.606 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Leishmania major T-complex protein 1, beta subunit, putative 0.0019 0.0005 0.0016
Giardia lamblia Aldose reductase 0.0122 0.0117 0.0523
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.001
Echinococcus multilocularis netrin receptor unc 5 0.0069 0.0059 0.0059
Schistosoma mansoni histone deacetylase 4 5 0.1789 0.1913 0.6376
Loa Loa (eye worm) pre-B cell enhancing factor 0.0358 0.0371 0.1456
Schistosoma mansoni amine GPCR 0.0032 0.002 0.0063
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Onchocerca volvulus Phospholipase A2 homolog 0.0071 0.0061 0.0599
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0012 0.0112
Plasmodium falciparum thioredoxin reductase 0.0049 0.0038 0.0146
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0053 0.0042 0.0138
Loa Loa (eye worm) hypothetical protein 0.0078 0.0068 0.0268
Echinococcus granulosus serotonin receptor 0.0032 0.002 0.0065
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0032 0.002 0.002
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0114 0.0107 0.0355
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0002 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0048 0.0184
Plasmodium vivax glutathione reductase, putative 0.0049 0.0038 0.0146
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0019 0.0005 0.0016
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0012 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0012 0.004
Schistosoma mansoni opsin-like receptor 0.0032 0.002 0.0063
Schistosoma mansoni neuropeptide receptor 0.0032 0.002 0.0063
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0068 0.0101
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0007 0.0025
Echinococcus multilocularis protein patched 0.0452 0.0472 0.0472
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0078 0.0068 0.0265
Loa Loa (eye worm) hypothetical protein 0.0427 0.0445 0.1747
Schistosoma mansoni myst-related protein 0.0027 0.0014 0.0043
Leishmania major histone deacetylase, putative 0.2068 0.2214 0.8693
Echinococcus granulosus sentrin specific protease 7 0.017 0.0168 0.056
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0066 0.0257
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0068 0.0101
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0002
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. 0.0047 0.0035 0.0054
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0002
Toxoplasma gondii histone lysine-specific demethylase 0.0427 0.0445 0.1745
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0019 0.0074
Loa Loa (eye worm) beta-glucuronidase 0.1332 0.142 0.5576
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.002 0.0063
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0017 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0229 0.0232 0.0911
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0012 0.0044
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0427 0.0445 0.1745
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0375 0.0389 0.1524
Loa Loa (eye worm) CXXC zinc finger family protein 0.0226 0.0229 0.0898
Onchocerca volvulus 0.0017 0.0003 0.0018
Brugia malayi manba-prov protein 0.0466 0.0487 0.191
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0017 0.0003 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Echinococcus granulosus histone deacetylase 6 0.1789 0.1913 0.6377
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.0163
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0066 0.0218
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0008 0.0029
Schistosoma mansoni hypothetical protein 0.0436 0.0454 0.1512
Loa Loa (eye worm) oxidoreductase 0.0122 0.0117 0.0457
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Trichomonas vaginalis CAMK family protein kinase 0.0439 0.0458 0.1797
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0003 0.001
Mycobacterium ulcerans hypothetical protein 0.0417 0.0434 0.0663
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0066 0.0258
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0022 0.0071
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.002 0.0074
Schistosoma mansoni adenosylhomocysteinase 0.1471 0.157 0.5232
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.001
Echinococcus multilocularis histone deacetylase 6 0.1789 0.1913 0.1913
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Plasmodium falciparum acyl-CoA synthetase 0.0194 0.0193 0.0757
Echinococcus multilocularis expressed conserved protein 0.0155 0.0152 0.0152
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0078 0.0068 0.0109
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0053 0.0042 0.016
Leishmania major GTP-binding protein, putative 0.0022 0.0008 0.0029
Onchocerca volvulus 0.0059 0.0048 0.0471
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0015 0.0001 0.0004
Onchocerca volvulus 0.0032 0.002 0.0187
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0054 0.0043 0.0416
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.017 0.0168 0.0558
Plasmodium falciparum adenosylhomocysteinase 0.2377 0.2546 1
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0035 0.0133
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0053 0.0042 0.0162
Echinococcus multilocularis protein dispatched 1 0.0516 0.0541 0.0541
Schistosoma mansoni amine GPCR 0.0032 0.002 0.0063
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0792 0.0839 0.3291
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0001 0.0003
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0015 0.006
Mycobacterium tuberculosis Conserved protein 0.0122 0.0117 0.0188
Echinococcus multilocularis Niemann Pick C1 protein 0.1505 0.1607 0.1607
Echinococcus granulosus histone deacetylase 6 0.1789 0.1913 0.6377
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.004 0.0154
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0051 0.0039 0.0129
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0439 0.0458 0.1797
Plasmodium falciparum large subunit rRNA methyltransferase, putative 0.0016 0.0002 0.0005
Echinococcus multilocularis integrin alpha ps 0.0032 0.0019 0.0019
Leishmania major cathepsin L-like protease 0.0063 0.0053 0.0204
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.006
Entamoeba histolytica alcohol dehydrogenase, putative 0.0122 0.0117 0.0455
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.002 0.002
Loa Loa (eye worm) patched family protein 0.0064 0.0054 0.021
Echinococcus multilocularis g protein coupled receptor 0.0032 0.002 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.002 0.0065
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0057 0.0046 0.0152
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Toxoplasma gondii histone deacetylase HDAC5 0.095 0.1008 0.3958
Echinococcus multilocularis serine threonine protein kinase 0.0016 0.0002 0.0002
Brugia malayi hypothetical protein 0.0016 0.0002 0.0005
Leishmania major phosphopantetheinyl transferase-like protein 0.0017 0.0003 0.0007
Loa Loa (eye worm) STAT protein 0.0158 0.0155 0.0608
Brugia malayi Steroid receptor seven-up type 2 0.0054 0.0043 0.0165
Plasmodium vivax hypothetical protein, conserved 0.0053 0.0042 0.016
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Trypanosoma cruzi metacaspase, putative 0.0053 0.0042 0.016
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0032 0.002 0.0063
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.002 0.0065
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0049 0.0038 0.0149
Mycobacterium ulcerans beta-lactamase 0.0229 0.0232 0.0352
Echinococcus granulosus somatostatin receptor 0.0032 0.002 0.0065
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0054 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0008
Schistosoma mansoni integrin alpha-ps 0.0067 0.0057 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0003 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0181 0.0602
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0053 0.0042 0.0162
Echinococcus granulosus putative ribosomal RNA methyltransferase/cell division FtsJ protein 0.0016 0.0002 0.0007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0054 0.0043 0.0142
Loa Loa (eye worm) hypothetical protein 0.0097 0.0089 0.0349
Schistosoma mansoni cellular tumor antigen P53 0.0323 0.0333 0.1107
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0054 0.0043 0.0167
Loa Loa (eye worm) hypothetical protein 0.2068 0.2214 0.8694
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0012 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0018 0.0004 0.0012
Echinococcus granulosus dnaJ subfamily B 0.2798 0.3 1
Echinococcus granulosus histone deacetylase 1 0.2068 0.2214 0.7379
Loa Loa (eye worm) hypothetical protein 0.0071 0.0061 0.024
Trichomonas vaginalis importin beta-1, putative 0.0038 0.0026 0.0098
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0017 0.0003 0.0069
Mycobacterium ulcerans putative fatty-acid--CoA ligase 0.0047 0.0035 0.005
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0016 0.0002 0.0006
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0038 0.0127
Schistosoma mansoni regulator of G protein signaling 0.0016 0.0002 0.0004
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0022 0.0084
Trypanosoma brucei hypothetical protein, conserved 0.0229 0.0232 0.0908
Toxoplasma gondii exonuclease III APE 0.0058 0.0048 0.0184
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0066 0.0098
Schistosoma mansoni opsin-like receptor 0.0032 0.002 0.0063
Echinococcus multilocularis adenosylhomocysteinase 0.2377 0.2546 0.2546
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0441 0.046 0.1804
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0181 0.018 0.0293
Echinococcus granulosus neuropeptide receptor 0.0032 0.002 0.0065
Brugia malayi Death domain containing protein 0.0069 0.0059 0.023
Schistosoma mansoni adenoreceptor 0.0032 0.002 0.0063
Loa Loa (eye worm) acetylcholinesterase 1 0.0066 0.0056 0.022
Echinococcus granulosus aldo keto reductase 0.0122 0.0117 0.0388
Onchocerca volvulus Serine\/threonine kinase homolog 0.0439 0.0458 0.4543
Echinococcus granulosus GPCR family 2 0.0097 0.0089 0.0296
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0042 0.016
Onchocerca volvulus 0.0122 0.0117 0.115
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0003 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0053 0.0042 0.0162
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0068 0.0101
Schistosoma mansoni ferritin 0.0017 0.0003 0.0008
Brugia malayi Disco-interacting protein 2 homolog 0.0047 0.0035 0.0135
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0048 0.0212
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0078 0.0068 0.0109
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0045 0.0034 0.0129
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0358 0.0371 0.1234
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0041 0.0158
Brugia malayi jmjC domain containing protein 0.0071 0.0061 0.0237
Onchocerca volvulus 0.0032 0.002 0.0187
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0078 0.0068 0.0101
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.001 0.0038
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0038 0.0147
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.0002
Schistosoma mansoni single-minded 0.006 0.0049 0.0161
Echinococcus multilocularis allatostatin A receptor 0.0032 0.002 0.002
Echinococcus granulosus integrin alpha 3 0.0115 0.0108 0.0361
Plasmodium vivax hypothetical protein, conserved 0.0427 0.0445 0.1745
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Echinococcus multilocularis caspase 0.0137 0.0132 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Schistosoma mansoni glutaminase 0.0934 0.0991 0.3301
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0038 0.0146
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0097 0.0089 0.0296
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0258 0.0263 0.0431
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.002 0.0063
Mycobacterium tuberculosis Conserved protein 0.0229 0.0232 0.0379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0053 0.0042 0.0162
Brugia malayi MH2 domain containing protein 0.023 0.0233 0.0912
Entamoeba histolytica Ran family GTPase 0.0022 0.0008 0.0029
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0061 0.024
Onchocerca volvulus 0.0032 0.002 0.0187
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0066 0.0258
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Schistosoma mansoni amine GPCR 0.0032 0.002 0.0063
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0247
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0427 0.0445 0.1481
Loa Loa (eye worm) AGC/NDR protein kinase 0.0015 0.0001 0.0004
Entamoeba histolytica hypothetical protein 0.0038 0.0026 0.0098
Leishmania major 4-coumarate:coa ligase-like protein 0.0258 0.0263 0.1031
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0003
Schistosoma mansoni endothelin-converting enzyme-related 0.0023 0.001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0229 0.0232 0.0911
Leishmania major metacaspase, putative 0.0053 0.0042 0.016
Giardia lamblia Hypothetical protein 0.0053 0.0042 0.0187
Echinococcus multilocularis histone deacetylase 1 0.2068 0.2214 0.2214
Toxoplasma gondii cytochrome p450 superfamily protein 0.0016 0.0002 0.0006
Echinococcus granulosus acetylcholinesterase 0.0066 0.0056 0.0187
Onchocerca volvulus 0.0032 0.002 0.0187
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.002 0.0077
Brugia malayi Patched protein homolog 1 0.0064 0.0054 0.0207
Leishmania major cytochrome p450-like protein 0.0016 0.0002 0.0006
Toxoplasma gondii patched family protein 0.0064 0.0054 0.0207
Brugia malayi peptidase family M13 containing protein 0.0023 0.001 0.0036
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0055 0.0044 0.0044
Schistosoma mansoni microtubule-associated protein tau 0.1451 0.1548 0.516
Brugia malayi PAS domain containing protein 0.006 0.0049 0.019
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0181 0.0181
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Trypanosoma brucei unspecified product 0.0067 0.0057 0.0219
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0014 0.0052
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0053 0.0042 0.016
Mycobacterium tuberculosis Probable reductase 0.0113 0.0106 0.0172
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.2377 0.2546 0.4199
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0016 0.0001 0.0003
Leishmania major hypothetical protein, conserved 0.0044 0.0032 0.0124
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0012 0.0047
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0452 0.0472 0.1852
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0043 0.0165
Echinococcus granulosus rrna methyltransferase 3 0.0016 0.0002 0.0007
Leishmania major UDP-galactopyranose mutase 0.0427 0.0445 0.1745
Entamoeba histolytica histone deacetylase, putative 0.2068 0.2214 0.8693
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0066 0.1472
Loa Loa (eye worm) Smad1 0.0016 0.0002 0.0006
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0053 0.0042 0.0042
Plasmodium vivax replication factor C subunit 1, putative 0.0032 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0071 0.0061 0.0239
Onchocerca volvulus Phospholipase A2 homolog 0.0336 0.0347 0.344
Leishmania major cathepsin L-like protease 0.0063 0.0053 0.0204
Echinococcus multilocularis Peptidase C54 0.0045 0.0034 0.0034
Giardia lamblia Histone deacetylase 0.2068 0.2214 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0012 0.0044
Brugia malayi CHE-14 protein 0.0452 0.0472 0.185
Schistosoma mansoni hypothetical protein 0.0499 0.0523 0.1741
Brugia malayi putative neuropeptide receptor 0.0032 0.002 0.0074
Toxoplasma gondii patched family protein 0.0064 0.0054 0.0207
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0076
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0083 0.0074 0.0287
Schistosoma mansoni ferritin 0.0017 0.0003 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.023 0.0233 0.0915
Schistosoma mansoni histone deacetylase 4 5 0.1789 0.1913 0.6376
Treponema pallidum NADH oxidase 0.0017 0.0003 0.0165
Loa Loa (eye worm) hypothetical protein 0.0988 0.105 0.4123
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0047 0.0035 0.0054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0258 0.0263 0.0431
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0012 0.0012
Trichomonas vaginalis antibiotic synthetase, putative 0.0078 0.0068 0.0265
Mycobacterium ulcerans hypothetical protein 0.0258 0.0263 0.04
Echinococcus multilocularis histone deacetylase 7 0.1789 0.1913 0.1913
Schistosoma mansoni niemann-pick C1 (NPC1) 0.1069 0.1137 0.3789
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0792 0.0839 0.3291
Echinococcus multilocularis carboxylesterase 5A 0.0066 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0066 0.0056 0.022
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0078 0.0068 0.0109
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Plasmodium falciparum histone deacetylase 1 0.2068 0.2214 0.8693
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0043 0.014
Brugia malayi Serotonin receptor 0.0032 0.002 0.0074
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0113 0.044
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0018 0.0004 0.0012
Echinococcus multilocularis sentrin specific protease 1 0.0015 0.0001 0.0001
Plasmodium falciparum replication factor C subunit 1, putative 0.0032 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0069 0.0059 0.0233
Trypanosoma cruzi polo-like protein kinase, putative 0.0439 0.0458 0.1797
Loa Loa (eye worm) hypothetical protein 0.0076 0.0066 0.0259
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0149 0.0145 0.0568
Echinococcus multilocularis histone deacetylase 8 0.0949 0.1008 0.1008
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0014 0.0054
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0003 0.001
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0017 0.0064
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.002 0.002
Mycobacterium ulcerans monoamine oxidase 0.0427 0.0445 0.0679
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0119 0.0113 0.044
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Mycobacterium tuberculosis Conserved hypothetical protein 0.0097 0.0089 0.0143
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0449 0.0469 0.1838
Schistosoma mansoni steroid hormone receptor ad4bp 0.0054 0.0043 0.014
Brugia malayi Muscleblind-like protein 0.015 0.0146 0.057
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0194 0.0193 0.0315
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0035 0.005
Echinococcus multilocularis integrin alpha ps 0.0067 0.0057 0.0057
Echinococcus granulosus protein kinase c iota type 0.0015 0.0001 0.0004
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0427 0.0445 0.0679
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0045 0.0034 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.004 0.0154
Plasmodium vivax SET domain protein, putative 0.0035 0.0022 0.0084
Loa Loa (eye worm) acetyltransferase 0.0495 0.0518 0.2033
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0054 0.0043 0.014
Trypanosoma cruzi aldo/keto reductase, putative 0.0122 0.0117 0.0455
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0122 0.0117 0.0388
Onchocerca volvulus 0.0035 0.0022 0.0212
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0078 0.0068 0.0265
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0097 0.0089 0.0294
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0022 0.0022
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.002 0.0063
Trichomonas vaginalis antibiotic synthetase, putative 0.0078 0.0068 0.0265
Schistosoma mansoni hypothetical protein 0.0032 0.002 0.0063
Onchocerca volvulus 0.0017 0.0003 0.0018
Schistosoma mansoni importin beta-1 0.0047 0.0035 0.0115
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.012 0.0194
Brugia malayi latrophilin 2 splice variant baaae 0.0209 0.021 0.0821
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0022 0.0071
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0066 0.0056 0.0185
Schistosoma mansoni potassium channel beta 0.0122 0.0117 0.0386
Loa Loa (eye worm) patched family protein 0.0064 0.0054 0.021
Loa Loa (eye worm) hypothetical protein 0.0336 0.0347 0.1363
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0017 0.0003 0.0007
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.002 0.0074
Echinococcus granulosus serine:threonine protein kinase N2 0.0015 0.0001 0.0004
Schistosoma mansoni smad 0.0016 0.0002 0.0003
Echinococcus granulosus lysine specific histone demethylase 1A 0.0427 0.0445 0.1483
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0066 0.1472
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0048 0.0159
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0086
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0035 0.005
Onchocerca volvulus 0.0122 0.0117 0.115
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Loa Loa (eye worm) hypothetical protein 0.0047 0.0035 0.0138
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.002 0.002
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.002 0.0063
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0003 0.0001
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0043 0.0043
Loa Loa (eye worm) histone deacetylase 3 0.2068 0.2214 0.8694
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0053 0.0042 0.0162
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Schistosoma mansoni ankyrin 23/unc44 0.0069 0.0059 0.0195
Brugia malayi hypothetical protein 0.0064 0.0054 0.0207
Loa Loa (eye worm) hypothetical protein 0.0047 0.0035 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0001 0.0003
Onchocerca volvulus 0.0017 0.0003 0.0018
Onchocerca volvulus 0.0054 0.0043 0.0416
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0122 0.0117 0.0455
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Loa Loa (eye worm) hypothetical protein 0.0194 0.0193 0.0759
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0181 0.018 0.0293
Loa Loa (eye worm) hypothetical protein 0.0071 0.0061 0.024
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0017 0.0003 0.0041
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0843 0.0893 0.0893
Onchocerca volvulus 0.0229 0.0232 0.2296
Leishmania major DNA polymerase kappa, putative 0.0102 0.0095 0.037
Loa Loa (eye worm) Ulp1 protease 0.0015 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Trichomonas vaginalis histone deacetylase, putative 0.2068 0.2214 0.8693
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0003 0.001
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0053 0.0042 0.0165
Brugia malayi Carboxylesterase family protein 0.0066 0.0056 0.0217
Schistosoma mansoni aldo-keto reductase 0.0122 0.0117 0.0386
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0048 0.0184
Trypanosoma brucei metacaspase 0.0053 0.0042 0.016
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.002 0.0063
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.001 0.0031
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0003 0.001
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0019 0.0005 0.0016
Schistosoma mansoni transient receptor potential channel 0.0095 0.0087 0.0287
Echinococcus granulosus BRCA1 associated protein 0.0044 0.0032 0.0108
Trichomonas vaginalis ferritin, putative 0.0017 0.0003 0.0009
Echinococcus granulosus cysteine protease atg4b 0.0045 0.0034 0.0112
Schistosoma mansoni hypothetical protein 0.2798 0.3 1
Brugia malayi larval opioid receptor 0.0032 0.002 0.0074
Schistosoma mansoni hypothetical protein 0.0209 0.021 0.0697
Echinococcus multilocularis dna polymerase eta 0.0116 0.011 0.011
Treponema pallidum nicotinate phosphoribosyltransferase 0.0066 0.0056 0.8469
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0181 0.0602
Trypanosoma cruzi aldo/keto reductase, putative 0.0122 0.0117 0.0455
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0048 0.0069
Brugia malayi hypothetical protein 0.0032 0.0019 0.0074
Echinococcus granulosus adenosylhomocysteinase 0.2377 0.2546 0.8487
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0022 0.0022
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.017 0.0168 0.0658
Brugia malayi Cathepsin L-like precursor 0.0017 0.0003 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.004 0.0154
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0068 0.0109
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Loa Loa (eye worm) hypothetical protein 0.084 0.089 0.3495
Loa Loa (eye worm) DR-78 0.0025 0.0012 0.0047
Loa Loa (eye worm) hypothetical protein 0.0096 0.0088 0.0346
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0032 0.0019 0.0074
Echinococcus granulosus biogenic amine 5HT receptor 0.0401 0.0417 0.1389
Echinococcus multilocularis musashi 0.003 0.0017 0.0017
Loa Loa (eye worm) steroid hormone receptor 0.0054 0.0043 0.0167
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0057 0.0046 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.002 0.002
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.002 0.0063
Brugia malayi AMP-binding enzyme family protein 0.0258 0.0263 0.1031
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0068 0.0265
Brugia malayi beta-lactamase family protein 0.0229 0.0232 0.0908
Loa Loa (eye worm) hypothetical protein 0.0427 0.0445 0.1747
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0019 0.0074
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0061 0.0201
Echinococcus multilocularis expressed conserved protein 0.0989 0.1051 0.1051
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0059 0.0233
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0068 0.0101
Trypanosoma cruzi metacaspase 5, putative 0.0053 0.0042 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.002 0.0063
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0002
Trypanosoma brucei aldo/keto reductase, putative 0.0122 0.0117 0.0455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Trypanosoma cruzi UDP-galactopyranose mutase 0.0427 0.0445 0.1745
Brugia malayi cytochrome P450 0.0016 0.0002 0.0006
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0137 0.0132 0.0439
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0068 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0054 0.0043 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0042 0.016
Brugia malayi hypothetical protein 0.0028 0.0015 0.0057
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0062 0.0243
Trypanosoma brucei DNA polymerase kappa, putative 0.0102 0.0095 0.037
Trypanosoma cruzi histone deacetylase, putative 0.1789 0.1913 0.7513
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0028 0.0015 0.0015
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0122 0.0117 0.0455
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0229 0.0232 0.0379
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0003 0.0001
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0053 0.0042 0.0162
Trypanosoma cruzi polo-like protein kinase, putative 0.0439 0.0458 0.1797
Schistosoma mansoni zinc finger protein 0.0025 0.0012 0.0037
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0048 0.0037 0.0121
Brugia malayi follicle stimulating hormone receptor 0.0269 0.0274 0.1075
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0032 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0083 0.0074 0.0287
Echinococcus multilocularis serine:threonine protein kinase N2 0.0015 0.0001 0.0001
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0017 0.0064
Echinococcus granulosus importin subunit beta 1 0.0047 0.0035 0.0117
Brugia malayi SWIRM domain containing protein 0.0427 0.0445 0.1745
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0003 0.0007
Onchocerca volvulus Putative ribosomal RNA methyltransferase 0.0016 0.0002 0.0014
Schistosoma mansoni integrin alpha-ps 0.0035 0.0022 0.0072
Brugia malayi ecdysone receptor 0.0025 0.0012 0.0044
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0117 0.0188
Trypanosoma brucei metacaspase 5, putative 0.0053 0.0042 0.016
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0122 0.0117 0.0388
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0003 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0181 0.0604
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0001 0.0003
Schistosoma mansoni ribosomal RNA methyltransferase 0.0016 0.0002 0.0005
Echinococcus multilocularis caspase 3 0.0084 0.0075 0.0075
Echinococcus granulosus integrin alpha ps 0.0032 0.0019 0.0064
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.6065 0.6521 1
Schistosoma mansoni tar DNA-binding protein 0.0317 0.0326 0.1085
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0122 0.0117 0.0455
Echinococcus granulosus expressed conserved protein 0.0155 0.0152 0.0507
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0003 0.0007
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.004 0.0028 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0054 0.0043 0.0167
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0008 0.0029
Brugia malayi nuclear receptor NHR-67 0.0025 0.0012 0.0044
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.002 0.002
Echinococcus multilocularis fmrfamide receptor 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0047 0.0035 0.0138
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.002 0.0063
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Echinococcus multilocularis microtubule associated protein 2 0.1451 0.1548 0.1548
Schistosoma mansoni hypothetical protein 0.0436 0.0454 0.1512
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0003 0.0096
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.002 0.0065
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0323 0.0333 0.1307
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0044 0.0032 0.0124
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0003 0.0055
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0113 0.0106 0.0172
Loa Loa (eye worm) hypothetical protein 0.0027 0.0014 0.0055
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0317 0.0326 0.128
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0054 0.0043 0.0165
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0015 0.0051
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0102 0.0095 0.037
Brugia malayi RNA recognition motif domain containing protein 0.0317 0.0326 0.1278
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0247
Loa Loa (eye worm) hypothetical protein 0.0078 0.0068 0.0268
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.002 0.0065
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0078 0.0068 0.0101
Echinococcus multilocularis zinc finger protein 0.0025 0.0012 0.0012
Onchocerca volvulus 0.0202 0.0202 0.1998
Entamoeba histolytica ribosomal RNA methyltransferase, putative 0.0016 0.0002 0.0005
Schistosoma mansoni histamine h1 receptor 0.0032 0.002 0.0063
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0001 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0317 0.0326 0.1085
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0016 0.0002 0.0002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.012 0.0465
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0019 0.0005 0.0014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0482 0.0505 0.168
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0495 0.0518 0.1724
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0194 0.0193 0.0759
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0122 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.001
Trypanosoma cruzi histone deacetylase, putative 0.0949 0.1008 0.3957
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0019 0.0074
Loa Loa (eye worm) hypothetical protein 0.0071 0.0061 0.024
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0016 0.0002 0.0006
Schistosoma mansoni intermediate filament proteins 0.003 0.0017 0.0053
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.002 0.0063
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0015 0.0049
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.0003 0.001
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.002 0.0063
Brugia malayi Cathepsin L-like precursor 0.0017 0.0003 0.0007
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.002 0.0187
Echinococcus multilocularis lamin dm0 0.003 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Echinococcus multilocularis sex peptide receptor 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0043 0.0167
Echinococcus granulosus neuropeptide s receptor 0.0519 0.0544 0.1812
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Trichomonas vaginalis histone deacetylase, putative 0.2068 0.2214 0.8693
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0003 0.0007
Echinococcus granulosus sentrin specific protease 1 0.0015 0.0001 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.2798 0.3 0.3
Trichomonas vaginalis ran, putative 0.0022 0.0008 0.0029
Echinococcus multilocularis tar DNA binding protein 0.0317 0.0326 0.0326
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0012 0.0038
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0208 0.0815
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0032 0.002 0.0065
Echinococcus granulosus lysine specific histone demethylase 1A 0.0427 0.0445 0.1483
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0001 0.0001
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.6065 0.6521 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0439 0.0458 0.1797
Echinococcus granulosus ferritin 0.0017 0.0003 0.001
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0078 0.0068 0.0228
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0258 0.0263 0.04
Echinococcus granulosus L aminoadipate semialdehyde 0.0059 0.0048 0.0161
Loa Loa (eye worm) hypothetical protein 0.0122 0.0117 0.0457
Onchocerca volvulus 0.002 0.0006 0.0052
Loa Loa (eye worm) hypothetical protein 0.0117 0.0111 0.0436
Loa Loa (eye worm) hypothetical protein 0.0116 0.011 0.0432
Trichomonas vaginalis adenylate cyclase, putative 0.0016 0.0001 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0002 0.0004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0015 0.0049
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0001 0.0003
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0016 0.0002 0.0012
Onchocerca volvulus 0.0064 0.0054 0.0524
Brugia malayi glutaminase DH11.1 0.0934 0.0991 0.389
Trypanosoma brucei unspecified product 0.0113 0.0107 0.0417
Trichomonas vaginalis CAMK family protein kinase 0.0218 0.0219 0.0859
Schistosoma mansoni Smad4 0.0016 0.0002 0.0003
Echinococcus granulosus Peptidase C54 0.0045 0.0034 0.0112
Trypanosoma brucei Metacaspase-4 0.0053 0.0042 0.016
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0017 0.0064
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0137 0.0132 0.0132
Echinococcus multilocularis tumor protein p63 0.2207 0.2363 0.2363
Echinococcus granulosus sterol regulatory element binding protein 0.0452 0.0472 0.1572
Entamoeba histolytica aldose reductase, putative 0.0122 0.0117 0.0455
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0111 0.0105 0.0409
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0137 0.0536
Toxoplasma gondii ribosomal RNA methyltransferase (FtsJ) family protein 0.0016 0.0002 0.0005
Loa Loa (eye worm) peptidase family M13 containing protein 0.0071 0.0061 0.024
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.002 0.0065
Trichomonas vaginalis aldo-keto reductase, putative 0.0122 0.0117 0.0455
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0132
Echinococcus multilocularis sentrin specific protease 8 0.0015 0.0001 0.0001
Trypanosoma brucei unspecified product 0.0067 0.0057 0.0219
Echinococcus multilocularis g protein coupled receptor 0.0032 0.002 0.002
Leishmania major protein kinase, putative 0.0017 0.0003 0.001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.004 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0439 0.0458 0.1797
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.002 0.002
Schistosoma mansoni kinase 0.0223 0.0226 0.075
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0122 0.0117 0.0388
Entamoeba histolytica aldose reductase, putative 0.0122 0.0117 0.0455
Loa Loa (eye worm) hypothetical protein 0.0452 0.0472 0.1852
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0001 0.0005
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.002 0.002
Echinococcus multilocularis GPCR, family 2 0.0097 0.0089 0.0089
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0043 0.0043
Plasmodium vivax metacaspase 1, putative 0.0053 0.0042 0.016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0022 0.0071
Echinococcus granulosus g protein coupled receptor 0.0032 0.002 0.0065
Mycobacterium ulcerans DNA polymerase IV 0.0119 0.0113 0.0169
Schistosoma mansoni DNA polymerase eta 0.0116 0.011 0.0364
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0046 0.0179
Toxoplasma gondii adenosylhomocysteinase, putative 0.2377 0.2546 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.006
Brugia malayi hypothetical protein 0.0016 0.0001 0.0003
Brugia malayi hypothetical protein 0.0032 0.002 0.0074
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0003 0.0007
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0012 0.0012
Brugia malayi N-terminal motif family protein 0.0326 0.0336 0.1315
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0014 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0113 0.044
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0003 0.001
Schistosoma mansoni caspase-7 (C14 family) 0.0053 0.0042 0.0136
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0003 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0439 0.0458 0.1797
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0021 0.0031
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.002 0.0063
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.002 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0113 0.044
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0001 0.0003
Giardia lamblia DNA damage repair protein 0.003 0.0017 0.0074
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.002 0.0077
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0047
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.001
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0053 0.0042 0.0187
Mycobacterium tuberculosis Probable esterase LipL 0.0229 0.0232 0.0379
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.002 0.002
Brugia malayi RNA binding protein 0.0317 0.0326 0.1278
Leishmania major prostaglandin f synthase, putative 0.0122 0.0117 0.0455
Entamoeba histolytica hypothetical protein 0.0017 0.0003 0.0007
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0048 0.7096
Loa Loa (eye worm) beta-lactamase 0.0229 0.0232 0.0911
Echinococcus multilocularis Smad4 0.0016 0.0002 0.0002
Brugia malayi Metabotropic glutamate receptor precursor. 0.0045 0.0033 0.0126
Mycobacterium ulcerans acyl-CoA synthetase 0.0258 0.0263 0.04
Onchocerca volvulus 0.0427 0.0445 0.4411
Mycobacterium ulcerans oxidoreductase 0.0122 0.0117 0.0175
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0001 0.0003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0061 0.0201
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0068 0.0265
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0012 0.0012
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0001 0.0003
Echinococcus granulosus histone deacetylase 3 0.2068 0.2214 0.7379
Brugia malayi Inositol-1 0.0076 0.0066 0.0258
Echinococcus granulosus single minded 2 0.0044 0.0032 0.0108
Loa Loa (eye worm) hypothetical protein 0.0194 0.0193 0.0759
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0003 0.001
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0427 0.0445 0.1481
Brugia malayi Dopamine receptor protein 1 0.0032 0.002 0.0074
Loa Loa (eye worm) histone deacetylase 7A 0.1789 0.1913 0.7513
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0258 0.0263 0.1029
Schistosoma mansoni zinc finger protein 0.0025 0.0012 0.0038
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0015 0.0001 0.0004
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0042 0.016
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0032 0.0124
Toxoplasma gondii HEAT repeat-containing protein 0.0047 0.0035 0.0135
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0122 0.0117 0.0455
Trypanosoma brucei polo-like protein kinase 0.0439 0.0458 0.1797
Echinococcus granulosus neuropeptide receptor A26 0.0519 0.0544 0.1812
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0016 0.0002 0.0007
Plasmodium falciparum nicotinate phosphoribosyltransferase, putative 0.0066 0.0056 0.0218
Brugia malayi Cytochrome P450 family protein 0.0016 0.0002 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0053 0.0042 0.0162
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Schistosoma mansoni ferritin light chain 0.0017 0.0003 0.0008
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0375 0.0389 0.1524
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.002 0.0077
Echinococcus multilocularis snurportin 1 0.0499 0.0523 0.0523
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0044 0.0032 0.0314
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.004 0.0154
Brugia malayi Patched related family protein 10 0.0064 0.0054 0.0207
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Onchocerca volvulus 0.0122 0.0117 0.115
Mycobacterium leprae putative cytochrome p450 0.0016 0.0002 0.0004
Brugia malayi nuclear receptor NHR-88 0.0054 0.0043 0.0165
Echinococcus multilocularis short transient receptor potential channel 6 0.0063 0.0053 0.0053
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0229 0.0232 0.0771
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0021 0.0031
Schistosoma mansoni hypothetical protein 0.0025 0.0012 0.0037
Plasmodium falciparum glutathione reductase 0.0049 0.0038 0.0146
Entamoeba histolytica beta-galactosidase, putative 0.0971 0.1031 0.4048
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0066 0.022
Echinococcus granulosus FTZ F1 alpha 0.0054 0.0043 0.0142
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0038 0.0026 0.0098
Mycobacterium ulcerans acyl-CoA synthetase 0.0258 0.0263 0.04
Entamoeba histolytica protein kinase, putative 0.0015 0.0001 0.0002
Echinococcus multilocularis aldo keto reductase 0.0122 0.0117 0.0117
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0007 0.0025
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0002 0.0002
Trichomonas vaginalis penicillin-binding protein, putative 0.0229 0.0232 0.0908
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0427 0.0445 0.1745
Mycobacterium tuberculosis Conserved protein 0.0229 0.0232 0.0379
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0258 0.0263 0.04
Leishmania major cathepsin L-like protease 0.0017 0.0003 0.0007
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0068 0.0058 0.0222
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0013 0.0047
Brugia malayi AKH receptor 0.0032 0.002 0.0074
Entamoeba histolytica acyl-CoA synthetase, putative 0.0258 0.0263 0.1031
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0012 0.0047
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Echinococcus granulosus transient receptor potential gamma protein 0.0095 0.0087 0.0289
Echinococcus granulosus mixed lineage leukemia protein mll 0.0058 0.0047 0.0158
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1466 0.1564 0.2578
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0229 0.0232 0.0379
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0005
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.007 0.006 0.0196
Loa Loa (eye worm) hypothetical protein 0.015 0.0146 0.0573
Loa Loa (eye worm) RNA binding protein 0.0317 0.0326 0.128
Brugia malayi Cathepsin L-like precursor 0.0017 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0076
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0043 0.0165
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0003 0.001
Brugia malayi Adenosylhomocysteinase 0.2377 0.2546 1
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0042 0.016
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0054 0.0043 0.0142
Schistosoma mansoni ferritin light chain 0.0017 0.0003 0.0008
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0047 0.0035 0.0054
Onchocerca volvulus 0.0032 0.002 0.0187
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0003 0.0076
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0015 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.0019 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0001 0.0001
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.002 0.0065
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.0647 0.0682 0.2271
Echinococcus multilocularis nicotinamide phosphoribosyltransferase 0.0358 0.0371 0.0371
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0003 0.0007
Trichomonas vaginalis aldo/keto reductase, putative 0.0122 0.0117 0.0455
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.001
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0053 0.0042 0.0138
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.0866 0.0918 0.3603
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.004 0.0154
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0001 0.0001
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0053 0.0042 0.014
Schistosoma mansoni hypothetical protein 0.0069 0.0059 0.0195
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.002 0.0065
Brugia malayi hypothetical protein 0.0028 0.0015 0.0057
Leishmania major hypothetical protein, conserved 0.0015 0.0001 0.0003
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0001 0.0001
Brugia malayi Transient-receptor-potential like protein 0.0035 0.0023 0.0086
Loa Loa (eye worm) hypothetical protein 0.0054 0.0043 0.0167
Brugia malayi hypothetical protein 0.0025 0.0012 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0053 0.0042 0.0162
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0181 0.0604
Brugia malayi Importin beta-1 subunit 0.0047 0.0035 0.0135
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0008
Echinococcus granulosus caspase 0.0137 0.0132 0.0439
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0122 0.0117 0.0388
Trypanosoma brucei 2'-O-ribose RNA methyltransferase SPB1 homolog 0.0016 0.0002 0.0005
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0181 0.0711
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Mycobacterium ulcerans acetyl-CoA synthetase 0.0078 0.0068 0.0101
Toxoplasma gondii ImpB/MucB/SamB family protein 0.005 0.0038 0.0147
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0023 0.001 0.0031
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0066 0.0257
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.002 0.002
Loa Loa (eye worm) intermediate filament protein 0.003 0.0017 0.0065
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0016 0.0001 0.0016
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0023 0.001 0.0031
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0013 0.0047
Echinococcus multilocularis histone deacetylase 0.1789 0.1913 0.1913
Trypanosoma cruzi hypothetical protein, conserved 0.0229 0.0232 0.0908
Echinococcus multilocularis importin subunit beta 1 0.0047 0.0035 0.0035
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0015 0.0057
Brugia malayi NADH-dependent xylose reductase 0.0122 0.0117 0.0455
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0044 0.0032 0.0124
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0078 0.0068 0.0265
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.002 0.0065
Echinococcus multilocularis nibrin 0.0032 0.0019 0.0019
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0066 0.0258
Plasmodium falciparum thioredoxin reductase 0.0017 0.0003 0.001
Trichomonas vaginalis esterase, putative 0.0229 0.0232 0.0908
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0053 0.0204
Brugia malayi amine oxidase, flavin-containing family protein 0.0427 0.0445 0.1745
Loa Loa (eye worm) hypothetical protein 0.0427 0.0445 0.1747
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0016 0.0002 0.0002
Brugia malayi Pre-B cell enhancing factor precursor 0.0358 0.0371 0.1454
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0001 0.0003
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0054 0.0043 0.0167
Schistosoma mansoni biogenic amine (5HT) receptor 0.0152 0.0148 0.0491
Trichomonas vaginalis glucosylceramidase, putative 0.0149 0.0145 0.0568
Echinococcus granulosus histone deacetylase 8 0.0949 0.1008 0.336
Trypanosoma brucei histone deacetylase 4 0.1789 0.1913 0.7513
Trichomonas vaginalis beta-mannosidase, putative 0.0466 0.0487 0.191
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0042 0.016
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.002 0.0077
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0002 0.0006
Trypanosoma brucei histone deacetylase 2 0.0949 0.1008 0.3957
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0035 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Loa Loa (eye worm) oxidoreductase 0.0122 0.0117 0.0457
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.004 0.0154
Leishmania major hypothetical protein, conserved 0.0229 0.0232 0.0908
Echinococcus multilocularis caspase 2 0.0053 0.0042 0.0042
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0016 0.0002 0.0008
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0044 0.0032 0.0124
Schistosoma mansoni aryl hydrocarbon receptor 0.0173 0.0171 0.0569
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.0113 0.044
Brugia malayi Patched family protein 0.0064 0.0054 0.0207
Schistosoma mansoni integrin alpha 0.0149 0.0146 0.0483
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0019 0.0074
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0068 0.0265
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0001 0.0002
Echinococcus granulosus Smad4 0.0016 0.0002 0.0005
Brugia malayi regulator of G-protein signaling egl-10 0.0016 0.0002 0.0005
Schistosoma mansoni biogenic amine (5HT) receptor 0.0401 0.0417 0.1386
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0038 0.0059
Giardia lamblia Kinase, AGC AKT 0.0083 0.0074 0.033
Schistosoma mansoni nuclear receptor 0.0025 0.0012 0.0038
Trypanosoma cruzi metacaspase 5, putative 0.0053 0.0042 0.016
Trypanosoma cruzi UDP-galactopyranose mutase 0.0427 0.0445 0.1745
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0181 0.0602
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0078 0.0068 0.0268
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0217 0.085
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0035 0.005
Loa Loa (eye worm) hypothetical protein 0.0258 0.0263 0.1034
Echinococcus multilocularis aldo keto reductase 0.0122 0.0117 0.0117
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0068 0.0265
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.0003 0.001
Brugia malayi topoisomerase 0.0032 0.0019 0.0074
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0078 0.0068 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0054 0.0043 0.0165
Loa Loa (eye worm) hypothetical protein 0.0949 0.1008 0.3958
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0054 0.0043 0.014
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0096 0.0088 0.0088
Onchocerca volvulus 0.0017 0.0003 0.0018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.2377 0.2546 1
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0032 0.0019 0.0074
Echinococcus multilocularis fmrfamide receptor 0.0032 0.002 0.002
Brugia malayi Dopamine receptor 0.0032 0.002 0.0074
Brugia malayi TAR-binding protein 0.0317 0.0326 0.1278
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0001 0.0005
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0002 0.0002
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.002 0.0065
Brugia malayi G protein-coupled receptor 0.0032 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0152 0.0148 0.0581
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0068 0.0265
Echinococcus multilocularis protein kinase c epsilon type 0.0016 0.0002 0.0002
Loa Loa (eye worm) Ulp1 protease 0.0015 0.0001 0.0003
Toxoplasma gondii aldo-keto reductase 0.0122 0.0117 0.0455
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0012 0.0044
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0096 0.0088 0.0292
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0122 0.0117 0.0455
Entamoeba histolytica acyl-CoA synthetase, putative 0.0258 0.0263 0.1031
Loa Loa (eye worm) hypothetical protein 0.0064 0.0054 0.021
Schistosoma mansoni amine GPCR 0.0032 0.002 0.0063
Brugia malayi Integrin alpha pat-2 precursor 0.0149 0.0146 0.057
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0019 0.0074
Echinococcus granulosus ecdysone induced protein 78C 0.0054 0.0043 0.0142
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.002 0.0063
Trichomonas vaginalis hypothetical protein 0.0028 0.0014 0.0054
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0054 0.0043 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0019 0.0074
Loa Loa (eye worm) T-complex protein 1 0.0019 0.0005 0.0019
Brugia malayi nuclear receptor NHR-88 0.0025 0.0012 0.0044
Schistosoma mansoni histone deacetylase hda2 0.1834 0.1961 0.6535
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0018 0.0004 0.0012
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0043 0.014
Mycobacterium leprae conserved hypothetical protein 0.0017 0.0003 0.0004
Schistosoma mansoni pol-related 0.0122 0.0117 0.0386
Echinococcus multilocularis cysteine protease 0.0017 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.002 0.0065
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.0089 0.0296
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0022 0.0071
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0038 0.0026 0.0098
Trichomonas vaginalis D-aminoacylase, putative 0.0229 0.0232 0.0908
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0003 0.001
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0003 0.0009
Loa Loa (eye worm) oxidoreductase 0.0122 0.0117 0.0457
Onchocerca volvulus 0.0032 0.002 0.0187
Onchocerca volvulus Netrin receptor homolog 0.0069 0.0059 0.0582
Schistosoma mansoni ferritin 0.0017 0.0003 0.0008
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0097 0.0089 0.0294
Loa Loa (eye worm) hypothetical protein 0.0113 0.0106 0.0418
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0499 0.0523 0.2054
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0122 0.0117 0.0455
Brugia malayi p70 ribosomal S6 kinase beta 0.0015 0.0001 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0003 0.0096
Schistosoma mansoni nuclear receptor 0.0025 0.0012 0.0038
Mycobacterium leprae Possible oxidoreductase 0.0122 0.0117 0.0452
Schistosoma mansoni caspase-7 (C14 family) 0.0137 0.0132 0.0437
Brugia malayi hypothetical protein 0.0016 0.0002 0.0005
Brugia malayi RNA, U transporter 1 0.0133 0.0128 0.05
Echinococcus granulosus g protein coupled receptor 0.0032 0.002 0.0065
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.002 0.0063
Loa Loa (eye worm) MH2 domain-containing protein 0.023 0.0233 0.0915
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0003 0.001
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0053 0.0042 0.0136
Loa Loa (eye worm) glutamate receptor 0.0018 0.0004 0.0014
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.002 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0053 0.0042 0.0162
Onchocerca volvulus 0.0235 0.0238 0.2354
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.002 0.0063
Echinococcus granulosus microtubule associated protein 2 0.1451 0.1548 0.5162
Echinococcus granulosus disco interacting protein 2 0.0047 0.0035 0.0117
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0003 0.001
Leishmania major cathepsin L-like protease 0.0017 0.0003 0.0007
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0068 0.0109
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0113 0.0106 0.0172
Entamoeba histolytica nicotinate phosphoribosyltransferase, putative 0.0066 0.0056 0.0218
Schistosoma mansoni metabotropic glutamate receptor 0.0022 0.0008 0.0025
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0427 0.0445 0.0445
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0018 0.0004 0.0012
Schistosoma mansoni caspase-3 (C14 family) 0.0137 0.0132 0.0437
Schistosoma mansoni hypothetical protein 0.0505 0.0529 0.1761
Trichomonas vaginalis glucosylceramidase, putative 0.0141 0.0137 0.0536
Leishmania major histone deacetylase, putative 0.2068 0.2214 0.8693
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0053 0.0042 0.0162
Trichomonas vaginalis AGC family protein kinase 0.0015 0.0001 0.0002
Plasmodium vivax patched family protein, putative 0.0064 0.0054 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.001 0.0038
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0047 0.0035 0.0054
Onchocerca volvulus 0.0017 0.0003 0.0018
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0122 0.0117 0.0455
Leishmania major cytochrome p450-like protein 0.0016 0.0002 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.002 0.0065
Loa Loa (eye worm) hypothetical protein 0.0032 0.002 0.0077
Echinococcus multilocularis replication factor c subunit 1 0.0032 0.002 0.002
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0017 0.0064

Activities

Activity type Activity value Assay description Source Reference
Agonism (functional) = 53 % Percent of effective dose for [3H]-estradiol against proliferation of MCF-7 cells. ChEMBL. 2769681
Agonism (functional) = 53 % Agonistic activity in MCF-7 cell proliferation. ChEMBL. 1738150
Agonism (functional) = 53 % Percent of effective dose for [3H]-estradiol against proliferation of MCF-7 cells. ChEMBL. 2769681
Agonism (functional) = 53 % Agonistic activity in MCF-7 cell proliferation. ChEMBL. 1738150
EC50 (functional) = 0.42 nM Effective dose for [3H]- estradiol against proliferation of MCF-7 cells ChEMBL. 2769681
EC50 (functional) = 0.42 nM Effective dose for [3H]- estradiol against proliferation of MCF-7 cells ChEMBL. 2769681
IC30 (functional) = 3.4 uM Inhibitory activity against proliferation of BT-20 cells in presence of TPE at 10e-5 M concentration. ChEMBL. 2769681
IC30 (functional) = 3.4 uM Inhibitory activity against proliferation of BT-20 cells in presence of TPE at 10e-5 M concentration. ChEMBL. 2769681
IC30 (functional) = 5.8 uM Inhibitory activity against proliferation of MCF-7 cells in presence of 10e-6 M concentration of [3H]- estradiol (E2) ChEMBL. 2769681
IC30 (functional) = 5.8 uM Inhibitory activity against proliferation of MCF-7 cells in presence of 10e-6 M concentration of [3H]- estradiol (E2) ChEMBL. 2769681
IC50 (functional) = 52 nM In vitro inhibition of MCF-7 cell proliferation compared to 0.1 nM [3H]-estradiol. ChEMBL. 2769681
IC50 (functional) = 52 nM In vitro inhibition of MCF-7 cell proliferation compared to 0.1 nM [3H]-estradiol. ChEMBL. 2769681
Inhibition (functional) = 51 % Percent of inhibitory activity versus 0.1 nm [3H]-estradiol against proliferation of MCF-7 cells. ChEMBL. 2769681
Inhibition (functional) = 51 % Percent of inhibitory activity against proliferation of BT-20 cells in presence of TPE at 10e-5 M concentration. ChEMBL. 2769681
Inhibition (functional) = 51 % Percent of inhibitory activity versus 0.1 nm [3H]-estradiol against proliferation of MCF-7 cells. ChEMBL. 2769681
Inhibition (functional) = 51 % Percent of inhibitory activity against proliferation of BT-20 cells in presence of TPE at 10e-5 M concentration. ChEMBL. 2769681
Inhibition (functional) = 60 % Percent of inhibitory activity against proliferation of MCF-7 cells in presence of 10e-6 M concentration of [3H]-estradiol (E2). ChEMBL. 2769681
Inhibition (functional) = 60 % Cytostastic activity against MCF-7 cell proliferation. ChEMBL. 1738150
Inhibition (functional) = 60 % Percent of inhibitory activity against proliferation of MCF-7 cells in presence of 10e-6 M concentration of [3H]-estradiol (E2). ChEMBL. 2769681
Inhibition (functional) = 60 % Cytostastic activity against MCF-7 cell proliferation. ChEMBL. 1738150
Inhibition (binding) = 87 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine and diolein(PS+DO) ChEMBL. 1738150
Inhibition (binding) = 87 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine and diolein(PS+DO) ChEMBL. 1738150
Inhibition (binding) = 111 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine and diolein(PS+DO) ChEMBL. 1738150
Inhibition (binding) = 111 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine and diolein(PS+DO) ChEMBL. 1738150
Inhibition (binding) = 119 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine (PS) ChEMBL. 1738150
Inhibition (binding) = 119 % Percent stimulation or inhibition of protein kinase C with [Ca2+] for phosphatidylserine (PS) ChEMBL. 1738150
RBA (binding) = 2.5 % Relative binding affinity was measured on calf uterus estrogen receptor after 5 hr at 25C. ChEMBL. 1738150
RBA (binding) = 2.5 % Relative binding affinity was measured on calf uterus estrogen receptor after 5 hr at 25C. ChEMBL. 1738150
RBA1 (binding) = 8.1 Relative binding affinity against estrogen receptor in calf uterus cytosol using [3H]-E2 as radioligand, incubated at 2 hours at 0 degree centigrade. ChEMBL. 2769681
RBA2 (binding) = 2.5 Relative binding affinity against estrogen receptor in calf uterus cytosol using [3H]-E2 as radioligand, incubated at 5 hours at 25 degree centigrade. ChEMBL. 2769681
Selectivity (binding) = 0.3 Selectivity for relative binding affinity against estrogen receptor at 2 hrs and 5 hr in calf uterus cytosol ChEMBL. 2769681

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 2769681

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

2 literature references were collected for this gene.

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