Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Peroxidase homolog | 0.1417 | 1 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | EGF-like domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | hypothetical protein | 0.0132 | 0.0752 | 0.0752 |
Onchocerca volvulus | Huntingtin homolog | 0.0132 | 0.0752 | 0.0721 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0034 | 0.0034 |
Schistosoma mansoni | notch | 0.0458 | 0.3099 | 0.3075 |
Onchocerca volvulus | 0.0458 | 0.3099 | 0.3075 | |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.0275 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0032 | 0.0034 | 0.0034 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | EGF-like domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0032 | 0.0034 | 0.0034 |
Schistosoma mansoni | peroxidasin | 0.1417 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0032 | 0.0034 | 0.0034 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0032 | 0.0034 | 0.0034 |
Brugia malayi | EGF-like domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0065 | 0.0275 | 0.5 |
Brugia malayi | Cadherin domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Schistosoma mansoni | notch | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0034 | 0.0034 |
Schistosoma mansoni | notch | 0.0458 | 0.3099 | 0.3075 |
Echinococcus granulosus | protein jagged 2 | 0.0458 | 0.3099 | 0.3075 |
Schistosoma mansoni | hypothetical protein | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | EGF-like domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | EGF-like domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Schistosoma mansoni | peroxidasin | 0.1417 | 1 | 1 |
Onchocerca volvulus | 0.0458 | 0.3099 | 0.3075 | |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Onchocerca volvulus | Slit protein homolog | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | ecdysteroid receptor | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Onchocerca volvulus | Peroxidasin homolog | 0.1417 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.0275 | 0.0241 |
Schistosoma mansoni | notch | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0032 | 0.0034 | 0.0034 |
Onchocerca volvulus | 0.1417 | 1 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Schistosoma mansoni | hypothetical protein | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | EGF-like domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | Notch2 | 0.0458 | 0.3099 | 0.3099 |
Echinococcus granulosus | neural cadherin | 0.0458 | 0.3099 | 0.3075 |
Echinococcus multilocularis | slit 2 protein | 0.0458 | 0.3099 | 0.3075 |
Onchocerca volvulus | Putative cubilin | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0032 | 0.0034 | 0.0034 |
Brugia malayi | EGF-like domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0034 | 0.0034 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | Muscle positioning protein 4 | 0.0458 | 0.3099 | 0.3099 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0458 | 0.3099 | 0.3075 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0034 | 0.0034 |
Brugia malayi | Animal haem peroxidase family protein | 0.1417 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.0275 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.1417 | 1 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0132 | 0.0752 | 0.0721 |
Brugia malayi | nuclear receptor NHR-88 | 0.0032 | 0.0034 | 0.0034 |
Echinococcus granulosus | protein jagged 1 | 0.0458 | 0.3099 | 0.3075 |
Onchocerca volvulus | 0.1417 | 1 | 1 | |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0065 | 0.0275 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.1417 | 1 | 1 |
Echinococcus multilocularis | fibropellin Ia | 0.0458 | 0.3099 | 0.3075 |
Echinococcus granulosus | delta-like protein 1 | 0.0458 | 0.3099 | 0.3075 |
Schistosoma mansoni | septate junction protein | 0.0458 | 0.3099 | 0.3075 |
Onchocerca volvulus | Peroxidase homolog | 0.1417 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.0752 | 0.0752 |
Schistosoma mansoni | hypothetical protein | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0032 | 0.0034 | 0.0034 |
Schistosoma mansoni | notch | 0.0458 | 0.3099 | 0.3075 |
Echinococcus granulosus | fibropellin Ia | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Echinococcus multilocularis | notch | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Schistosoma mansoni | cell polarity protein | 0.0458 | 0.3099 | 0.3075 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0034 | 0.0034 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.0275 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Brugia malayi | Delta serrate ligand family protein | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Schistosoma mansoni | notch | 0.0458 | 0.3099 | 0.3075 |
Echinococcus granulosus | notch | 0.0458 | 0.3099 | 0.3075 |
Schistosoma mansoni | hypothetical protein | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0032 | 0.0034 | 0.0034 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.1417 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.1417 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0 | 0.5 |
Onchocerca volvulus | 0.0458 | 0.3099 | 0.3075 | |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0032 | 0.0034 | 0.0034 |
Schistosoma mansoni | hypothetical protein | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | animal heme peroxidase | 0.1417 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.1417 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0032 | 0.0034 | 0.0034 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0032 | 0.0034 | 0.0034 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Echinococcus multilocularis | peroxidasin | 0.1417 | 1 | 1 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | notch-like transmembrane receptor | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.0752 | 0.0752 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0065 | 0.0275 | 0.0241 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0458 | 0.3099 | 0.3075 |
Onchocerca volvulus | 0.1417 | 1 | 1 | |
Brugia malayi | Animal haem peroxidase family protein | 0.1417 | 1 | 1 |
Echinococcus granulosus | protein jagged 2 | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.0275 | 0.0241 |
Echinococcus granulosus | slit 2 protein | 0.0458 | 0.3099 | 0.3075 |
Onchocerca volvulus | 0.0458 | 0.3099 | 0.3075 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.1417 | 1 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0458 | 0.3099 | 0.3075 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0065 | 0.0275 | 1 |
Echinococcus granulosus | peroxidasin | 0.1417 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.1417 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.1417 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0458 | 0.3099 | 0.3075 |
Echinococcus multilocularis | protein jagged 2 | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | Peroxidasin | 0.1417 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0458 | 0.3099 | 0.3075 |
Giardia lamblia | High cysteine protein | 0.0458 | 0.3099 | 0.5 |
Loa Loa (eye worm) | notch protein | 0.0458 | 0.3099 | 0.3099 |
Onchocerca volvulus | Dual oxidase homolog | 0.1417 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | nuclear hormone receptor | 0.0032 | 0.0034 | 0.0034 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0032 | 0.0034 | 0.0034 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0065 | 0.0275 | 0.0886 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0032 | 0.0034 | 0.0034 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0458 | 0.3099 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Schistosoma mansoni | slit | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0034 | 0.0034 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.1417 | 1 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0458 | 0.3099 | 0.3099 |
Echinococcus multilocularis | neural cadherin | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0032 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | animal heme peroxidase | 0.1417 | 1 | 1 |
Echinococcus multilocularis | protein jagged 1 | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | steroid hormone receptor | 0.0032 | 0.0034 | 0.0034 |
Onchocerca volvulus | 0.0458 | 0.3099 | 0.3075 | |
Echinococcus multilocularis | protein jagged 1 | 0.0458 | 0.3099 | 0.3075 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.3099 | 0.3099 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0032 | 0.0034 | 0.0034 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0458 | 0.3099 | 0.3075 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0032 | 0.0034 | 0.0034 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0848 | 0.5907 | 0.5893 |
Loa Loa (eye worm) | hypothetical protein | 0.1417 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.