Detailed information for compound 1061602

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 462.928 | Formula: C25H23ClN4O3
  • H donors: 2 H acceptors: 4 LogP: 4.38 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: C#CCn1cc(C(=O)NC(c2ccccc2)C(=O)NC2CCCC2)c(=O)c2c1nc(Cl)cc2
  • InChi: 1S/C25H23ClN4O3/c1-2-14-30-15-19(22(31)18-12-13-20(26)28-23(18)30)24(32)29-21(16-8-4-3-5-9-16)25(33)27-17-10-6-7-11-17/h1,3-5,8-9,12-13,15,17,21H,6-7,10-11,14H2,(H,27,33)(H,29,32)
  • InChiKey: DBQMJVRZXGFLGX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0013 0.0119
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0015 0.0026
Echinococcus granulosus mitogen activated protein kinase 0.012 0.0124 0.1025
Loa Loa (eye worm) hypothetical protein 0.004 0.0034 0.0407
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.004 0.0034 0.0407
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0016 0.0191
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0139 0.024
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0013 0.015
Brugia malayi Calcitonin receptor-like protein seb-1 0.0162 0.0171 0.2033
Brugia malayi latrophilin 2 splice variant baaae 0.0111 0.0113 0.1348
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Plasmodium falciparum cysteine proteinase falcipain 1 0.0019 0.001 0.0731
Leishmania major cathepsin L-like protease 0.0141 0.0148 1
Echinococcus multilocularis tumor protein p63 0.1084 0.1207 0.209
Schistosoma mansoni intermediate filament proteins 0.0118 0.0121 0.1181
Echinococcus granulosus microtubule associated protein 2 0.0741 0.0821 0.6802
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Brugia malayi hypothetical protein 0.0024 0.0015 0.0184
Loa Loa (eye worm) hypothetical protein 0.0759 0.0841 1
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0034 0.0027
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0019 0.001 0.0676
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.001 0.0676
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Giardia lamblia Kinase, CMGC MAPK 0.012 0.0124 0.9426
Onchocerca volvulus 0.0021 0.0013 0.073
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0031 0.0052
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.012 0.0124 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Echinococcus multilocularis neuropeptide receptor A26 0.05 0.0551 0.0953
Trypanosoma brucei protein kinase, putative 0.012 0.0124 0.8384
Mycobacterium ulcerans pantoate--beta-alanine ligase 0.8912 1 1
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0037 0.0031 0.153
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0045 0.0039 0.0465
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.012 0.0124 0.8384
Plasmodium falciparum plasmepsin X 0.0037 0.0031 0.2206
Plasmodium falciparum plasmepsin I 0.0037 0.0031 0.2206
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0012 0.086
Onchocerca volvulus Huntingtin homolog 0.0135 0.014 0.839
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0034 1
Schistosoma mansoni apoferritin-2 0.0027 0.0019 0.0183
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0034 0.0027
Brugia malayi Cathepsin L-like precursor 0.0037 0.0031 0.0364
Echinococcus multilocularis protein dispatched 1 0.0047 0.0041 0.0071
Brugia malayi Intermediate filament tail domain containing protein 0.0118 0.0121 0.1442
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0009 0.0083
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Entamoeba histolytica hypothetical protein 0.0154 0.0162 1
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0048 0.3237
Trypanosoma cruzi cysteine peptidase, putative 0.0141 0.0148 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0015 0.0008
Echinococcus granulosus histone deacetylase 6 0.0132 0.0137 0.113
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0009 0.0071
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.0019 0.0012
Trichomonas vaginalis BRCA1-associated protein, putative 0.0014 0.0005 0.0208
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0034 0.2253
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0068 0.0066 0.3311
Schistosoma mansoni cathepsin D (A01 family) 0.0037 0.0031 0.0294
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0034 0.1719
Brugia malayi CHE-14 protein 0.0041 0.0035 0.0414
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0129 0.0134 0.9065
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0024 0.0016 0.0152
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0034 0.0033
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0029 0.0022
Leishmania major histone deacetylase, putative 0.0132 0.0137 0.9249
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.012 0.0124 0.8384
Schistosoma mansoni cathepsin D (A01 family) 0.0037 0.0031 0.0294
Loa Loa (eye worm) MH2 domain-containing protein 0.0262 0.0283 0.3364
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0013 0.015
Echinococcus multilocularis histone deacetylase 6 0.0132 0.0137 0.0236
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0024 0.0016 0.1145
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0031 0.0295
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0057 0.0053 0.0434
Schistosoma mansoni hypothetical protein 0.0439 0.0482 0.4703
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0034 0.1719
Toxoplasma gondii aspartyl protease 0.0037 0.0031 0.003
Toxoplasma gondii cathepsin CPL 0.0037 0.0031 0.003
Echinococcus multilocularis lamin dm0 0.0118 0.0121 0.0209
Brugia malayi hypothetical protein 0.0053 0.0048 0.0572
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Trichomonas vaginalis histone deacetylase, putative 0.0068 0.0066 0.3311
Schistosoma mansoni thyroid hormone receptor 0.0045 0.0039 0.0378
Brugia malayi histone deacetylase 3 (HD3) 0.0068 0.0066 0.0779
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0013 0.0119
Brugia malayi Cathepsin L-like precursor 0.0037 0.0031 0.0364
Onchocerca volvulus 0.004 0.0033 0.1982
Toxoplasma gondii pantoate-beta-alanine ligase 0.8912 1 1
Trypanosoma cruzi histone deacetylase, putative 0.0132 0.0137 0.9249
Echinococcus granulosus Niemann Pick C1 protein 0.0095 0.0096 0.0791
Schistosoma mansoni cathepsin F (C01 family) 0.0037 0.0031 0.0295
Schistosoma mansoni retinoic acid receptor RXR 0.0045 0.0039 0.0378
Brugia malayi histone deacetylase 11 0.0068 0.0066 0.0779
Loa Loa (eye worm) histone deacetylase 3 0.0068 0.0066 0.0779
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0013 0.073
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0045 0.0039 0.0067
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0127 0.0132 0.128
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0465
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0012 0.0004
Echinococcus granulosus lamin 0.0118 0.0121 0.1002
Schistosoma mansoni nuclear receptor 0.0021 0.0013 0.0119
Loa Loa (eye worm) steroid hormone receptor 0.0045 0.0039 0.0465
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0045 0.0039 0.0465
Brugia malayi MH1 domain containing protein 0.0018 0.0009 0.0106
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0014 0.0005 0.0054
Schistosoma mansoni histone deacetylase 1 2 3 0.0068 0.0066 0.0635
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0017 0.0835
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.001 0.0676
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0024 0.0016 0.0152
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0045 0.0039 0.0465
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0037 0.0031 0.0363
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0034 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.001 0.0507
Echinococcus granulosus high affinity choline transporter 1 0.036 0.0393 0.3254
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.02
Toxoplasma gondii histone deacetylase HDAC1 0.0132 0.0137 0.0136
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0012 0.0795
Schistosoma mansoni histone deacetylase 4 5 0.0132 0.0137 0.1331
Loa Loa (eye worm) hypothetical protein 0.004 0.0034 0.0407
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0047 0.0553
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0142 0.1172
Onchocerca volvulus 0.004 0.0034 0.2026
Plasmodium vivax histone deacetylase, putative 0.0068 0.0066 0.4772
Schistosoma mansoni Smad4 0.0018 0.0009 0.0083
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0127 0.0132 0.1087
Schistosoma mansoni cathepsin F (C01 family) 0.0025 0.0017 0.016
Brugia malayi nuclear receptor RXR 0.0024 0.0015 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0139 0.1352
Schistosoma mansoni hypothetical protein 0.0575 0.0635 0.6199
Plasmodium vivax aspartyl protease, putative 0.0037 0.0031 0.2206
Onchocerca volvulus 0.004 0.0034 0.2026
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0047 0.0553
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.012 0.0124 0.8384
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0127 0.0132 0.6673
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0162 0.0171 0.2033
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0016 0.0191
Schistosoma mansoni histone deacetylase 0.0068 0.0066 0.0635
Schistosoma mansoni inositol monophosphatase 0.004 0.0034 0.0324
Schistosoma mansoni memapsin-2 (A01 family) 0.0922 0.1025 1
Entamoeba histolytica cysteine proteinase, putative 0.0025 0.0017 0.1016
Echinococcus granulosus cathepsin l1 0.0025 0.0017 0.0136
Brugia malayi nuclear receptor NHR-67 0.0021 0.0013 0.015
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0048 0.3237
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0037 0.0031 0.0364
Loa Loa (eye worm) hypothetical protein 0.0037 0.0031 0.0363
Loa Loa (eye worm) hypothetical protein 0.0118 0.0121 0.1442
Trichomonas vaginalis histone deacetylase, putative 0.0068 0.0066 0.3311
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0034 0.1691
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.001 0.0097
Brugia malayi CXXC zinc finger family protein 0.0031 0.0024 0.028
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0014 0.0005 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0124 0.1207
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0037 0.0031 0.0294
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0045 0.0039 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0025 0.0017 0.0835
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Echinococcus granulosus smad 0.0018 0.0009 0.0071
Plasmodium vivax vivapain-2 0.0037 0.0031 0.2215
Echinococcus multilocularis histone deacetylase 1 0.0068 0.0066 0.0113
Loa Loa (eye worm) hypothetical protein 0.019 0.0203 0.241
Plasmodium falciparum histone deacetylase, putative 0.0132 0.0137 1
Trypanosoma cruzi cysteine proteinase, putative 0.0019 0.001 0.0676
Loa Loa (eye worm) hypothetical protein 0.0055 0.005 0.0599
Trypanosoma brucei histone deacetylase 2 0.0068 0.0066 0.4414
Brugia malayi hypothetical protein 0.0037 0.0031 0.0363
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0024 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0015 0.0007
Plasmodium vivax unspecified product 0.0019 0.001 0.0731
Echinococcus multilocularis dnaJ subfamily B 0.0439 0.0482 0.0834
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0015 0.0174
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0465
Trypanosoma cruzi cysteine protease, putative 0.0019 0.001 0.0676
Onchocerca volvulus 0.0037 0.0031 0.1811
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0057 0.0053 0.0091
Loa Loa (eye worm) hypothetical protein 0.004 0.0034 0.0407
Toxoplasma gondii aspartyl protease ASP1 0.0037 0.0031 0.003
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0045 0.0039 0.0321
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.004 0.0033 0.0057
Schistosoma mansoni ferritin 0.0027 0.0019 0.0183
Brugia malayi Cathepsin L-like precursor 0.0025 0.0017 0.02
Loa Loa (eye worm) histone deacetylase 0.0132 0.0137 0.1626
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0045 0.0039 0.0465
Loa Loa (eye worm) hypothetical protein 0.0041 0.0035 0.0414
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0045 0.0039 0.0465
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Plasmodium falciparum histone deacetylase 1 0.0068 0.0066 0.4772
Echinococcus multilocularis ferritin 0.0027 0.0019 0.0033
Brugia malayi histone deacetylase 1 (HD1) 0.0068 0.0066 0.0779
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0034 0.0026
Echinococcus granulosus sodium:myo inositol cotransporter 0.004 0.0033 0.0274
Entamoeba histolytica hypothetical protein 0.0154 0.0162 1
Toxoplasma gondii ABC1 family protein 0.004 0.0034 0.0034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0198 0.0211 0.0365
Plasmodium vivax vivapain-1 0.0019 0.001 0.0731
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0048 0.35
Echinococcus granulosus BRCA1 associated protein 0.0014 0.0005 0.0034
Onchocerca volvulus Huntingtin homolog 0.0135 0.014 0.839
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0184
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0013 0.0101
Trypanosoma cruzi cruzipain precursor, putative 0.0141 0.0148 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0053 0.0628
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0009 0.0106
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0095 0.0096 0.5908
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0127 0.0132 0.8895
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0034 0.0027
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0012 0.0894
Trichomonas vaginalis histone deacetylase, putative 0.0068 0.0066 0.3311
Leishmania major cathepsin L-like protease 0.0037 0.0031 0.2048
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0045 0.0039 0.0067
Loa Loa (eye worm) hypothetical protein 0.0135 0.014 0.1668
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0031 0.1537
Brugia malayi cathepsin L-like precursor 0.0025 0.0017 0.02
Leishmania major hypothetical protein, conserved 0.0014 0.0005 0.0278
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0031 0.1537
Trypanosoma cruzi cruzipain precursor, putative 0.0012 0.0003 0.0154
Brugia malayi hypothetical protein 0.0154 0.0162 0.1925
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0045 0.0039 0.0378
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0047 0.008
Schistosoma mansoni cathepsin s 0.0012 0.0003 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Giardia lamblia Hypothetical protein 0.0024 0.0016 0.1191
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0034 0.028
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0037 0.0031 0.0052
Echinococcus multilocularis cysteine protease 0.0037 0.0031 0.0052
Brugia malayi ecdysteroid receptor 0.0045 0.0039 0.0465
Echinococcus granulosus cathepsin L cysteine proteinase 0.0037 0.0031 0.025
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0037 0.0031 0.0363
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0048 0.35
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0015 0.0007
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0063 0.006 0.0712
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0009 0.0015
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0024 0.0016 0.0191
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0024 0.0015 0.0125
Onchocerca volvulus Histone deacetylase 10 homolog 0.0068 0.0066 0.3902
Schistosoma mansoni inositol transporter 0.004 0.0033 0.0323
Leishmania major cathepsin L-like protease 0.0141 0.0148 1
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0012 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0045 0.0039 0.0465
Schistosoma mansoni ap endonuclease 0.0021 0.0012 0.0114
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0039 0.0378
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0015 0.0966
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0024 0.0016 0.0967
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.001 0.0617
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0045 0.0039 0.0321
Brugia malayi Histone deacetylase 1 0.0068 0.0066 0.0779
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0008 0.0567
Echinococcus granulosus histone deacetylase 6 0.0146 0.0152 0.126
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.001 0 0.0005
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0027 0.0019 0.3284
Echinococcus granulosus histone deacetylase 1 0.0068 0.0066 0.0539
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.012 0.0124 0.8384
Mycobacterium ulcerans hypothetical protein 0.004 0.0034 0.0026
Trichomonas vaginalis ferritin, putative 0.0027 0.0019 0.0956
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0139 0.1352
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0184
Entamoeba histolytica cysteine proteinase 1, putative 0.0019 0.001 0.0617
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0031 0.1537
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0013 0.0021
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.012 0.0124 0.1474
Echinococcus multilocularis geminin 0.0575 0.0635 0.11
Brugia malayi hypothetical protein 0.0024 0.0015 0.0184
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0211 0.2057
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0031 0.1869
Echinococcus multilocularis solute carrier family 5 0.004 0.0033 0.0057
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0127 0.0132 0.128
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0015 0.0184
Schistosoma mansoni inositol monophosphatase 0.004 0.0034 0.0324
Onchocerca volvulus 0.0021 0.0013 0.073
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0097
Schistosoma mansoni inositol transporter 0.004 0.0033 0.0323
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0039 0.0067
Loa Loa (eye worm) hypothetical protein 0.0077 0.0076 0.0901
Schistosoma mansoni microtubule-associated protein tau 0.0741 0.0821 0.8012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0037 0.0031 0.0294
Echinococcus granulosus geminin 0.0575 0.0635 0.5262
Schistosoma mansoni hypothetical protein 0.0154 0.0162 0.1577
Onchocerca volvulus Cathepsin F homolog 0.0037 0.0031 0.1811
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0015 0.0147
Brugia malayi Smad1 0.0018 0.0009 0.0106
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Entamoeba histolytica cysteine protease, putative 0.0037 0.0031 0.1869
Toxoplasma gondii histone deacetylase HDAC5 0.0068 0.0066 0.0065
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0012 0.0795
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0031 0.1811
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0068 0.0066 0.3311
Onchocerca volvulus 0.004 0.0034 0.2026
Brugia malayi hypothetical protein 0.0021 0.0013 0.015
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0127 0.0132 0.8895
Schistosoma mansoni histone deacetylase 4 5 0.0132 0.0137 0.1331
Trypanosoma cruzi major cysteine proteinase, putative 0.0111 0.0114 0.7692
Plasmodium falciparum plasmepsin VII 0.0037 0.0031 0.2206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0015 0.0007
Onchocerca volvulus 0.0045 0.0039 0.2322
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0045 0.0039 0.0465
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Leishmania major cathepsin L-like protease 0.0141 0.0148 1
Schistosoma mansoni histone deacetylase hda2 0.0146 0.0152 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0045 0.0039 0.0378
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0211 0.2057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0045 0.0039 0.0465
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0035 0.0414
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0031 0.1537
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0045 0.0039 0.0465
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0034 0.1719
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0039 0.0067
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0014 0.0005 0.03
Echinococcus granulosus histone deacetylase 0.0132 0.0137 0.113
Plasmodium falciparum plasmepsin II 0.0037 0.0031 0.2206
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0174
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0013 0.015
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.0019 1
Leishmania major cathepsin L-like protease 0.0037 0.0031 0.2048
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0037 0.0031 0.0294
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0045 0.0039 0.0378
Brugia malayi nuclear receptor RXR 0.0021 0.0013 0.015
Echinococcus multilocularis musashi 0.0118 0.0121 0.0209
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0198 0.0211 0.0365
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0012 0.0003 0.0032
Brugia malayi Pepsin A precursor 0.0037 0.0031 0.0363
Trypanosoma cruzi histone deacetylase 1, putative 0.0068 0.0066 0.4414
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0465
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0024 0.0015 0.0026
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0035 0.0285
Schistosoma mansoni hypothetical protein 0.0575 0.0635 0.6199
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0024 0.0016 0.0027
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0031 0.0052
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Entamoeba histolytica cysteine proteinase 2 0.0019 0.001 0.0617
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0154 0.0162 0.028
Mycobacterium ulcerans lipase LipD 0.004 0.0034 0.0026
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.019 0.0203 0.241
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0037 0.0031 0.1869
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0142 0.0245
Schistosoma mansoni histone deacetylase hda2 0.0068 0.0066 0.0635
Mycobacterium tuberculosis Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.8912 1 1
Loa Loa (eye worm) DR-78 0.0021 0.0013 0.015
Mycobacterium tuberculosis Conserved protein 0.004 0.0034 0.0027
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0034 0.2291
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.0019 0.0011
Brugia malayi beta-lactamase 0.004 0.0034 0.0407
Plasmodium falciparum plasmepsin IX 0.0037 0.0031 0.2206
Onchocerca volvulus 0.0037 0.0031 0.1803
Leishmania major cathepsin L-like protease 0.0037 0.0031 0.2048
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0035 0.0285
Brugia malayi Sodium:solute symporter family protein 0.004 0.0033 0.0398
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0045 0.0039 0.0465
Echinococcus multilocularis histone deacetylase 6 0.0146 0.0152 0.0263
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.001 0.0097
Plasmodium vivax vivapain-3 0.0019 0.001 0.0731
Echinococcus multilocularis Niemann Pick C1 protein 0.0095 0.0096 0.0165
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0031 0.1537
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0184
Brugia malayi Histone deacetylase family protein 0.0132 0.0137 0.1626
Echinococcus granulosus neuropeptide s receptor 0.05 0.0551 0.456
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0016 0.0795
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Echinococcus granulosus cysteine protease 0.0019 0.001 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0045 0.0039 0.0465
Schistosoma mansoni cpg binding protein 0.0033 0.0026 0.0245
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0016 0.1059
Mycobacterium tuberculosis Conserved protein 0.004 0.0034 0.0027
Plasmodium falciparum plasmepsin VIII, putative 0.0037 0.0031 0.2206
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0174
Trypanosoma brucei histone deacetylase 1 0.0068 0.0066 0.4414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.001 0.0507
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0034 0.0058
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.001 0.0124
Plasmodium vivax plasmepsin V, putative 0.0037 0.0031 0.2206
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0034 0.0059
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0008 0.5
Loa Loa (eye worm) cysteine protease 0.0037 0.0031 0.0364
Brugia malayi hypothetical protein 0.0021 0.0013 0.015
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0009 0.0071
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0045 0.0039 0.2322
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Brugia malayi aspartic protease BmAsp-1, identical 0.0037 0.0031 0.0363
Schistosoma mansoni ap endonuclease 0.0021 0.0012 0.0114
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0047 0.008
Echinococcus multilocularis lamin 0.0118 0.0121 0.0209
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0013 0.073
Schistosoma mansoni smad 0.0018 0.0009 0.0083
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0045 0.0039 0.0465
Schistosoma mansoni sodium/solute symporter 0.004 0.0033 0.0323
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0013 0.0021
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0016 0.0191
Brugia malayi beta-lactamase family protein 0.004 0.0034 0.0407
Echinococcus granulosus expressed conserved protein 0.0089 0.0089 0.0737
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0016 0.0191
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0037 0.0031 0.0294
Brugia malayi hypothetical protein 0.0759 0.0841 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0012 0.0005
Echinococcus granulosus solute carrier family 5 0.004 0.0033 0.0274
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0034 0.1691
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0019 0.001 0.0097
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0013 0.015
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Schistosoma mansoni patched 1 0.0041 0.0035 0.0336
Entamoeba histolytica hypothetical protein 0.0154 0.0162 1
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Brugia malayi Eukaryotic aspartyl protease family protein 0.0037 0.0031 0.0363
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0124 0.629
Loa Loa (eye worm) hypothetical protein 0.0159 0.0167 0.1987
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0024 0.0016 0.0016
Brugia malayi conserved hypotetical protein 0.0021 0.0013 0.015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0034 0.033
Loa Loa (eye worm) hypothetical protein 0.005 0.0045 0.0537
Trypanosoma cruzi cysteine peptidase, putative 0.0141 0.0148 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0031 0.1537
Plasmodium vivax aspartyl protease, putative 0.0037 0.0031 0.2206
Echinococcus multilocularis histone deacetylase 7 0.0132 0.0137 0.0236
Toxoplasma gondii exonuclease III APE 0.0021 0.0012 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0016 0.1059
Schistosoma mansoni hypothetical protein 0.0051 0.0047 0.045
Mycobacterium tuberculosis Conserved protein 0.004 0.0034 0.0027
Trypanosoma cruzi histone deacetylase, putative 0.0132 0.0137 0.9249
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0015 0.0174
Trypanosoma cruzi cysteine peptidase, putative 0.0012 0.0003 0.0154
Entamoeba histolytica histone deacetylase, putative 0.0068 0.0066 0.4028
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Echinococcus granulosus cathepsin l cysteine peptidase 0.0037 0.0031 0.025
Brugia malayi Cathepsin L-like precursor 0.0037 0.0031 0.0364
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0139 0.0132
Plasmodium vivax histone deacetylase 1, putative 0.0068 0.0066 0.4772
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.0019 0.0005
Plasmodium falciparum histone deacetylase 2 0.0132 0.0137 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0012 0.0795
Brugia malayi tailless protein 0.0021 0.0013 0.015
Loa Loa (eye worm) hypothetical protein 0.0055 0.005 0.0599
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0127 0.0132 0.8118
Loa Loa (eye worm) hypothetical protein 0.004 0.0034 0.0407
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0047 0.0553
Schistosoma mansoni hypothetical protein 0.0039 0.0033 0.032
Schistosoma mansoni ferritin 0.0027 0.0019 0.0183
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0045 0.0039 0.0465
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.0013 0.0119
Loa Loa (eye worm) hypothetical protein 0.0135 0.014 0.1668
Echinococcus multilocularis histone deacetylase 6 0.0132 0.0137 0.0236
Loa Loa (eye worm) hypothetical protein 0.0095 0.0096 0.114
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0012 0.086
Loa Loa (eye worm) hypothetical protein 0.0127 0.0132 0.1564
Trypanosoma cruzi histone deacetylase, putative 0.0068 0.0066 0.4414
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0034 0.1719
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0045 0.0039 0.0465
Echinococcus multilocularis BRCA1 associated protein 0.0014 0.0005 0.0007
Echinococcus granulosus cpg binding protein 0.0033 0.0026 0.0208
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0039 0.0321
Schistosoma mansoni cpg binding protein 0.0033 0.0026 0.0245
Schistosoma mansoni ferritin 0.0027 0.0019 0.0183
Loa Loa (eye worm) hypothetical protein 0.036 0.0393 0.4672
Schistosoma mansoni hypothetical protein 0.0111 0.0113 0.1103
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0013 0.0021
Echinococcus multilocularis sodium:glucose cotransporter 2 0.004 0.0033 0.0057
Loa Loa (eye worm) hypothetical protein 0.004 0.0034 0.0407
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0012 0.0145
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0 0.0005
Giardia lamblia Histone deacetylase 0.0068 0.0066 0.4962
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0 0.0005
Trypanosoma brucei histone deacetylase 4 0.0132 0.0137 0.9249
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0035 0.006
Echinococcus granulosus lamin dm0 0.0118 0.0121 0.1002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0154 0.0162 0.1339
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0034 0.0407
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0015 0.0966
Schistosoma mansoni hypothetical protein 0.0039 0.0033 0.032
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0118 0.0121 0.1442
Echinococcus granulosus mitogen activated protein kinase 3 0.012 0.0124 0.1025
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.001 0 0.0005
Onchocerca volvulus 0.0118 0.0121 0.7252
Brugia malayi hypothetical protein 0.0037 0.0031 0.0363
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0024 0.0016 0.1145
Plasmodium vivax histone deacetylase 2, putative 0.0132 0.0137 1
Echinococcus granulosus histone deacetylase 7 0.0132 0.0137 0.113
Schistosoma mansoni high-affinity choline transporter 0.036 0.0393 0.3834
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0013 0.0101
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0465
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0465
Echinococcus granulosus GPCR family 2 0.0051 0.0047 0.0382
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0045 0.0039 0.0465
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0047 0.0382
Trypanosoma cruzi cysteine peptidase, putative 0.0141 0.0148 1
Brugia malayi nuclear receptor NHR-88 0.0045 0.0039 0.0465
Schistosoma mansoni histone deacetylase 0.0068 0.0066 0.0635
Trypanosoma brucei histone deacetylase 3 0.0132 0.0137 0.9249
Echinococcus multilocularis histone deacetylase 0.0132 0.0137 0.0236
Brugia malayi MH2 domain containing protein 0.0262 0.0283 0.3364
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0258 0.0278 0.0271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0016 0.0795
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0013 0.0101
Entamoeba histolytica hypothetical protein 0.0154 0.0162 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0045 0.0039 0.0465
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0037 0.0031 0.0294
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0015 0.0881
Leishmania major cysteine peptidase A (CPA) 0.0037 0.0031 0.2048
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0097
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0465
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Echinococcus multilocularis mitogen activated protein kinase 0.012 0.0124 0.0214
Echinococcus granulosus cathepsin L 0.0019 0.001 0.0083
Loa Loa (eye worm) inositol-1 0.004 0.0034 0.04
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0019 0.001 0.0676
Echinococcus multilocularis sodium:myo inositol cotransporter 0.004 0.0033 0.0057
Loa Loa (eye worm) hypothetical protein 0.0063 0.006 0.0715
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0012 0.0597
Schistosoma mansoni nuclear receptor 0.0021 0.0013 0.0119
Echinococcus granulosus intermediate filament protein 0.0118 0.0121 0.1002
Schistosoma mansoni hypothetical protein 0.0039 0.0033 0.032
Schistosoma mansoni thyroid hormone receptor 0.0045 0.0039 0.0378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Brugia malayi Cathepsin L-like cysteine proteinase 0.0025 0.0017 0.02
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0015 0.0174
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0536 0.0591 0.702
Leishmania major hypothetical protein, conserved 0.004 0.0034 0.2291
Echinococcus multilocularis histone deacetylase 8 0.0068 0.0066 0.0113
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0013 0.015
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0013 0.015
Onchocerca volvulus 0.0037 0.0031 0.1811
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0009 0.0106
Plasmodium vivax hypothetical protein, conserved 0.004 0.0034 0.2477
Leishmania major cathepsin L-like protease 0.0037 0.0031 0.2048
Echinococcus multilocularis smad 0.0018 0.0009 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Trypanosoma cruzi histone deacetylase, putative 0.0132 0.0137 0.9249
Trypanosoma brucei histone deacetylase, putative 0.0132 0.0137 0.9249
Brugia malayi nuclear receptor NHR-88 0.0021 0.0013 0.015
Schistosoma mansoni hypothetical protein 0.0051 0.0047 0.045
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0013 0.0101
Toxoplasma gondii histone deacetylase HDAC3 0.0068 0.0066 0.0065
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0005 0.0278
Brugia malayi follicle stimulating hormone receptor 0.0536 0.0591 0.702
Loa Loa (eye worm) hypothetical protein 0.0111 0.0113 0.1348
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.02
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0024 0.0016 0.1191
Schistosoma mansoni cpg binding protein 0.0031 0.0024 0.0226
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0037 0.0031 0.2215
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0034 0.2057
Mycobacterium leprae Probable lipase LipE 0.004 0.0034 0.002
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0034 0.0027
Echinococcus granulosus histone deacetylase 6 0.0132 0.0137 0.113
Onchocerca volvulus 0.0037 0.0031 0.1811
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0015 0.0007
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0012 0.0597
Plasmodium falciparum plasmepsin VI 0.0037 0.0031 0.2206
Onchocerca volvulus Cathepsin L homolog 0.0037 0.0031 0.1811
Plasmodium falciparum plasmepsin III 0.0037 0.0031 0.2206
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.012 0.0124 0.8384
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0034 0.0026
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0037 0.0031 0.0364
Schistosoma mansoni ferritin light chain 0.0027 0.0019 0.0183
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.001 0.0676
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0016 0.0191
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0016 0.1059
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.0019 0.0011
Brugia malayi intermediate filament protein 0.0118 0.0121 0.1442
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0012 0.0726
Trichomonas vaginalis esterase, putative 0.004 0.0034 0.1719
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Echinococcus granulosus histone deacetylase 8 0.0068 0.0066 0.0539
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0132 0.6673
Brugia malayi Cathepsin L-like precursor 0.0012 0.0003 0.0032
Schistosoma mansoni brca1-associated protein (brap2) 0.0014 0.0005 0.004
Brugia malayi nuclear hormone receptor 0.0045 0.0039 0.0465
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0034 0.1691
Plasmodium falciparum plasmepsin V 0.0037 0.0031 0.2206
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0037 0.0031 0.003
Brugia malayi BRCA1-associated protein 2 containing protein 0.0014 0.0005 0.0054
Echinococcus multilocularis neuropeptide s receptor 0.05 0.0551 0.0953
Plasmodium vivax aspartyl protease, putative 0.0037 0.0031 0.2206
Echinococcus multilocularis cysteine protease 0.0037 0.0031 0.0052
Loa Loa (eye worm) aspartyl protease 6 0.0037 0.0031 0.0363
Schistosoma mansoni cellular tumor antigen P53 0.0159 0.0167 0.1628
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0037 0.0031 0.1537
Echinococcus granulosus survival motor neuron protein 1 0.0759 0.0841 0.697
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0015 0.0007
Plasmodium vivax unspecified product 0.0012 0.0003 0.0167
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0034 0.2253
Schistosoma mansoni transcription factor LCR-F1 0.0154 0.0162 0.1577
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0034 0.0027
Loa Loa (eye worm) hypothetical protein 0.0068 0.0066 0.0779
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0015 0.0881
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0015 0.0881
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0005 0.0278
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0005 0.03
Loa Loa (eye worm) hypothetical protein 0.0037 0.0031 0.0364
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0465
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Echinococcus multilocularis cpg binding protein 0.0033 0.0026 0.0043
Onchocerca volvulus Protein ultraspiracle homolog 0.0045 0.0039 0.2322
Loa Loa (eye worm) hypothetical protein 0.0162 0.0171 0.2033
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0016 0.1059
Onchocerca volvulus Bile acid receptor homolog 0.0045 0.0039 0.2322
Echinococcus multilocularis GPCR, family 2 0.0051 0.0047 0.008
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0124 0.629
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0031 0.1537
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0031 0.1537
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0031 0.1537
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0032
Brugia malayi Cathepsin L-like precursor 0.0025 0.0017 0.02
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0024 0.0016 0.0027
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0162 0.0171 0.2033
Onchocerca volvulus 0.0037 0.0031 0.1811
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0015 0.0007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0013 0.0021
Schistosoma mansoni hypothetical protein 0.0051 0.0047 0.045
Brugia malayi GH02984p 0.036 0.0393 0.4672
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0034 0.2253
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0034 0.2291
Echinococcus multilocularis cathepsin L cysteine protease 0.0037 0.0031 0.0052
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.515 0.5774 1
Onchocerca volvulus 0.0023 0.0015 0.0854
Echinococcus granulosus ferritin 0.0027 0.0019 0.0156
Onchocerca volvulus 0.0031 0.0024 0.1386
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0031 0.2048
Schistosoma mansoni zinc finger protein 0.0021 0.0013 0.0119
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0062 0.0605
Echinococcus granulosus Smad4 0.0018 0.0009 0.0071
Echinococcus granulosus sodium:glucose cotransporter 0.004 0.0033 0.0274
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0024 0.0016 0.0129
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0139 0.1147
Plasmodium vivax aspartyl proteinase, putative 0.0037 0.0031 0.2206
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0045 0.0039 0.0321
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.001 0 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0034 0.2291
Loa Loa (eye worm) transcription factor SMAD2 0.0262 0.0283 0.3364
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0034 0.2253
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0198 0.0211 0.251
Loa Loa (eye worm) hypothetical protein 0.0068 0.0066 0.0779
Echinococcus granulosus ubiquitin specific protease 41 0.0127 0.0132 0.1087
Brugia malayi MAP kinase sur-1 0.012 0.0124 0.1474
Schistosoma mansoni hypothetical protein 0.0039 0.0033 0.032
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0013 0.0021
Plasmodium falciparum cysteine proteinase falcipain 3 0.0037 0.0031 0.2215
Brugia malayi cytoplasmic intermediate filament protein 0.0063 0.006 0.0712
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.001 0.0617
Echinococcus multilocularis mitogen activated protein kinase 3 0.012 0.0124 0.0214
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0016 0.0967
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0037 0.0031 0.0294
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0034 0.1719
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0015 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Schistosoma mansoni peptidase 0.0011 0.0002 0.0012
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0024 0.0015 0.0184
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0127 0.0132 0.8895
Schistosoma mansoni lamin 0.0118 0.0121 0.1181
Echinococcus multilocularis high affinity choline transporter 1 0.036 0.0393 0.068
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Schistosoma mansoni smad1 5 8 and 0.0018 0.0009 0.0083
Schistosoma mansoni ferritin 0.0027 0.0019 0.0183
Onchocerca volvulus 0.0118 0.0121 0.7252
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Brugia malayi ecdysone receptor 0.0021 0.0013 0.015
Loa Loa (eye worm) hypothetical protein 0.0116 0.0119 0.1414
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.02
Leishmania major hypothetical protein, conserved 0.0053 0.0048 0.3237
Toxoplasma gondii aspartyl protease ASP3 0.0037 0.0031 0.003
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.012 0.0124 0.8384
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0045 0.0039 0.0465
Onchocerca volvulus 0.0159 0.0167 1
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0024 0.0016 0.0129
Loa Loa (eye worm) hypothetical protein 0.0037 0.0031 0.0363
Brugia malayi Cathepsin L-like precursor 0.0037 0.0031 0.0364
Loa Loa (eye worm) histone deacetylase 1 0.0068 0.0066 0.0779
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0045 0.0039 0.0378
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0024 0.0015 0.0147
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0127 0.0132 0.1087
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0037 0.0031 0.0294
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0039 0.0321
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0139 0.0131
Brugia malayi Inositol-1 0.004 0.0034 0.04
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0098 0.0948
Echinococcus granulosus dnaJ subfamily B 0.0439 0.0482 0.3993
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0097
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0013 0.015
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0024 0.0016 0.0027
Echinococcus granulosus ecdysone induced protein 78C 0.0045 0.0039 0.0321
Brugia malayi Steroid receptor seven-up type 2 0.0045 0.0039 0.0465
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0155 0.0163 0.1935
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0013 0.015
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0015 0.0966
Echinococcus multilocularis expressed protein 0.0027 0.0019 0.0033
Schistosoma mansoni hypothetical protein 0.0051 0.0047 0.045
Echinococcus granulosus cathepsin l1 0.0037 0.0031 0.025
Brugia malayi Papain family cysteine protease containing protein 0.0037 0.0031 0.0364
Loa Loa (eye worm) hypothetical protein 0.0051 0.0047 0.0553
Brugia malayi aspartic protease BmAsp-2, identical 0.0037 0.0031 0.0363
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0016 0.0795
Loa Loa (eye worm) hypothetical protein 0.0037 0.0031 0.0363
Plasmodium vivax histone deacetylase, putative 0.0132 0.0137 1
Echinococcus granulosus cathepsin L cysteine protease 0.0019 0.001 0.0083
Brugia malayi cathepsin F-like cysteine proteinase 0.0012 0.0003 0.0032
Plasmodium vivax vivapain-2 0.0037 0.0031 0.2215
Brugia malayi hypothetical protein 0.0034 0.0027 0.0323
Leishmania major hypothetical protein, conserved 0.0014 0.0005 0.0278
Mycobacterium ulcerans hypothetical protein 0.0023 0.0015 0.0007
Onchocerca volvulus 0.0155 0.0163 0.9736
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0048 0.0048
Toxoplasma gondii histone deacetylase HDAC4 0.0068 0.0066 0.0065
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.004 0.0033 0.0274
Loa Loa (eye worm) Smad1 0.0018 0.0009 0.0106
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0037 0.0031 0.0249
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0039 0.0378
Leishmania major cathepsin L-like protease 0.0037 0.0031 0.2048
Onchocerca volvulus 0.0025 0.0017 0.0984
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0198 0.0211 0.251
Brugia malayi Niemann-Pick C1 protein precursor 0.0095 0.0096 0.114
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.012 0.0124 0.8384
Echinococcus granulosus tumor protein p63 0.1084 0.1207 1
Brugia malayi hypothetical protein 0.001 0 0.0005
Schistosoma mansoni apoferritin-2 0.0027 0.0019 0.0183
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.004 0.0033 0.0033
Loa Loa (eye worm) histone deacetylase 7A 0.0132 0.0137 0.1626
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0127 0.0132 0.1564
Trichomonas vaginalis brca1-associated protein, putative 0.0014 0.0005 0.0208
Schistosoma mansoni hypothetical protein 0.0024 0.0015 0.0147
Trichomonas vaginalis histone deacetylase, putative 0.0068 0.0066 0.3311
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0034 0.0027
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0465
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Onchocerca volvulus 0.0037 0.0031 0.1811
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0045 0.0039 0.0465
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0097
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0005 0.0278
Echinococcus granulosus FTZ F1 alpha 0.0045 0.0039 0.0321
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0184
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0015 0.0007
Brugia malayi steroid hormone receptor 0.0045 0.0039 0.0465
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0097
Leishmania major histone deacetylase, putative 0.0068 0.0066 0.4414
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0139 0.939
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0039 0.0465
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.015
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0012 0.0795
Schistosoma mansoni smad1 5 8 and 0.0018 0.0009 0.0083
Trichomonas vaginalis histone deacetylase, putative 0.0068 0.0066 0.3311
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Leishmania major histone deacetylase, putative 0.0132 0.0137 0.9249
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Brugia malayi Histone deacetylase family protein 0.0132 0.0137 0.1626
Echinococcus granulosus sodium:glucose cotransporter 2 0.004 0.0033 0.0274
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.0019 0.0012
Trichomonas vaginalis histone deacetylase, putative 0.0068 0.0066 0.3311
Trichomonas vaginalis conserved hypothetical protein 0.0185 0.0197 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0037 0.0031 0.0052
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0048 0.35
Brugia malayi MH2 domain containing protein 0.0018 0.0009 0.0106
Brugia malayi Cathepsin L-like precursor 0.0037 0.0031 0.0364
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0037 0.0031 0.2215
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0013 0.0119
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0013 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0015 0.0174
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0124 0.629
Echinococcus granulosus expressed protein 0.0027 0.0019 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0045 0.0039 0.0465
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0045 0.0039 0.0378
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0013 0.0101
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0008 0.0001
Echinococcus multilocularis histone deacetylase 3 0.0068 0.0066 0.0113
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0012 0.0097
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0008 0.0567
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.001 0.0617
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0127 0.0132 0.0227
Echinococcus multilocularis expressed conserved protein 0.0089 0.0089 0.0154
Plasmodium vivax plasmepsin IV, putative 0.0037 0.0031 0.2206
Loa Loa (eye worm) intermediate filament protein 0.0118 0.0121 0.1442
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0016 0.0795
Onchocerca volvulus 0.0037 0.0031 0.1811
Loa Loa (eye worm) beta-lactamase 0.004 0.0034 0.0407
Loa Loa (eye worm) fibroinase 0.0037 0.0031 0.0364
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0032
Brugia malayi MH2 domain containing protein 0.0018 0.0009 0.0106
Schistosoma mansoni survival motor neuron protein 0.0155 0.0163 0.1585
Trypanosoma cruzi histone deacetylase 1, putative 0.0068 0.0066 0.4414
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0035 0.175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Echinococcus multilocularis thyroid hormone receptor alpha 0.0045 0.0039 0.0067
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0029 0.0014
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0013 0.0101
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0005 0.0278
Schistosoma mansoni coup transcription factor 0.0045 0.0039 0.0378
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0184
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0015 0.0125
Onchocerca volvulus 0.0037 0.0031 0.1803
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0198 0.0211 0.2057
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0016 0.0191
Mycobacterium ulcerans beta-lactamase 0.004 0.0034 0.0026
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0127 0.0132 0.8895
Echinococcus multilocularis microtubule associated protein 2 0.0741 0.0821 0.1421
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0139 0.0138
Schistosoma mansoni ferritin light chain 0.0027 0.0019 0.0183
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0045 0.0039 0.0321
Plasmodium falciparum plasmepsin IV 0.0037 0.0031 0.2206
Loa Loa (eye worm) ctsf protein 0.0037 0.0031 0.0364
Mycobacterium leprae conserved hypothetical protein 0.004 0.0034 0.002
Echinococcus multilocularis Smad4 0.0018 0.0009 0.0015
Echinococcus multilocularis cathepsin L 0.0019 0.001 0.0017
Toxoplasma gondii histone deacetylase HDAC2 0.0068 0.0066 0.0065
Brugia malayi photoreceptor-specific nuclear receptor 0.0045 0.0039 0.0465
Loa Loa (eye worm) hypothetical protein 0.0053 0.0048 0.0572
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0127 0.0132 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0055 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0037 0.0031 0.1537
Echinococcus granulosus neuropeptide receptor A26 0.05 0.0551 0.456
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0068 0.0066 0.3311
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0034 0.0027
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0045 0.0039 0.0465
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0127 0.0132 0.6673
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.001 0.0124
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0013 0.0119
Loa Loa (eye worm) hypothetical protein 0.004 0.0033 0.0398
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0045 0.0039 0.0321
Schistosoma mansoni lamin 0.0118 0.0121 0.1181
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0037 0.0031 0.0294
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0013 0.015
Echinococcus multilocularis FTZ F1 alpha 0.0045 0.0039 0.0067
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0037 0.0031 0.003
Schistosoma mansoni RAR-like nuclear receptor 0.0045 0.0039 0.0378
Trichomonas vaginalis CMGC family protein kinase 0.012 0.0124 0.629
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0127 0.0132 0.0227
Onchocerca volvulus 0.0037 0.0031 0.1811
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0045 0.0039 0.0067
Echinococcus multilocularis survival motor neuron protein 1 0.0759 0.0841 0.1457
Brugia malayi hypothetical protein 0.0135 0.014 0.1668
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0024 0.0016 0.1145
Brugia malayi MH1 domain containing protein 0.0018 0.0009 0.0106
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0198 0.0211 0.1747
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0024 0.0016 0.0152
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0047 0.0382
Schistosoma mansoni smad1 5 8 and 0.0018 0.0009 0.0083
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0048 0.3237
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0014 0.0005 0.0253
Leishmania major histone deacetylase, putative 0.0068 0.0066 0.4414
Loa Loa (eye worm) histone deacetylase 11 0.0068 0.0066 0.0779
Loa Loa (eye worm) hypothetical protein 0.001 0 0.0005
Echinococcus multilocularis protein patched 0.0041 0.0035 0.006
Trypanosoma cruzi histone deacetylase, putative 0.0068 0.0066 0.4414
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.001 0.0617
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0198 0.0211 0.1747
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0141 0.0148 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0139 0.0131
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.001 0 0.0005
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0034 0.0026
Schistosoma mansoni hypothetical protein 0.0155 0.0163 0.1585
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0037 0.0031 0.1537
Plasmodium vivax aspartyl proteinase, putative 0.0037 0.0031 0.2206
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0037 0.0031 0.0294
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0016 0.0795
Schistosoma mansoni brca1-associated protein (brap2) 0.0014 0.0005 0.004
Brugia malayi ubiquitin specific protease 14 0.001 0 0.0005
Brugia malayi beta-lactamase family protein 0.004 0.0034 0.0407
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0024 0.028
Schistosoma mansoni steroid hormone receptor ad4bp 0.0045 0.0039 0.0378
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0014 0.0005 0.0245
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0005 0.0278
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0034 0.0407
Echinococcus granulosus histone deacetylase 3 0.0068 0.0066 0.0539
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0139 0.0131
Echinococcus multilocularis ecdysone induced protein 78C 0.0045 0.0039 0.0067
Entamoeba histolytica cysteine protease, putative 0.0019 0.001 0.0617
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0024 0.0016 0.1145
Echinococcus multilocularis ubiquitin specific protease 41 0.0127 0.0132 0.0227
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0034 0.0275
Brugia malayi nuclear hormone receptor 0.0021 0.0013 0.015
Brugia malayi Cathepsin L-like precursor 0.0037 0.0031 0.0364

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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