Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cysteine peptidase A (CPA) | 0.0782 | 0.3695 | 0.3462 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0782 | 0.3695 | 0.3695 |
Loa Loa (eye worm) | fibroinase | 0.0782 | 0.3695 | 0.2855 |
Brugia malayi | Cathepsin L-like precursor | 0.0782 | 0.3695 | 0.3695 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0782 | 0.3695 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0782 | 0.3695 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0782 | 0.3695 | 0.2855 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0782 | 0.3695 | 0.3695 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0782 | 0.3695 | 0.3695 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0536 | 0.1176 | 0.1176 |
Leishmania major | cathepsin L-like protease | 0.0782 | 0.3695 | 0.3462 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1397 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1397 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Echinococcus granulosus | cathepsin b | 0.1397 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0553 | 0.1353 | 0.1353 |
Plasmodium vivax | vivapain-2 | 0.0782 | 0.3695 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0782 | 0.3695 | 0.3695 |
Brugia malayi | Cathepsin L-like precursor | 0.0536 | 0.1176 | 0.1176 |
Onchocerca volvulus | Cathepsin F homolog | 0.0782 | 0.3695 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0782 | 0.3695 | 0.3695 |
Loa Loa (eye worm) | cysteine protease | 0.0782 | 0.3695 | 0.2855 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0782 | 0.3695 | 0.3695 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0553 | 0.1353 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0536 | 0.1176 | 0.3182 |
Echinococcus granulosus | cathepsin l1 | 0.0536 | 0.1176 | 0.1176 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0782 | 0.3695 | 0.3695 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0782 | 0.3695 | 0.3695 |
Loa Loa (eye worm) | cathepsin B | 0.0553 | 0.1353 | 0.0201 |
Leishmania major | cathepsin L-like protease | 0.0782 | 0.3695 | 0.3462 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0782 | 0.3695 | 0.2855 |
Brugia malayi | Cathepsin L-like precursor | 0.0782 | 0.3695 | 0.3695 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0536 | 0.1176 | 0.1176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0553 | 0.1353 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0553 | 0.1353 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0782 | 0.3695 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0782 | 0.3695 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1397 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0536 | 0.1176 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0782 | 0.3695 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Onchocerca volvulus | 0.0782 | 0.3695 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0782 | 0.3695 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1213 | 0.8117 | 0.8117 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1213 | 0.8117 | 0.8117 |
Echinococcus multilocularis | cathepsin b | 0.1397 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0782 | 0.3695 | 0.3695 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0607 | 0.1903 | 0.1903 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1397 | 1 | 1 |
Onchocerca volvulus | 0.0782 | 0.3695 | 1 | |
Leishmania major | cathepsin L-like protease | 0.1213 | 0.8117 | 1 |
Onchocerca volvulus | 0.0782 | 0.3695 | 1 | |
Onchocerca volvulus | 0.0782 | 0.3695 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0782 | 0.3695 | 0.3462 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Leishmania major | cathepsin L-like protease | 0.0782 | 0.3695 | 0.3462 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1397 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0782 | 0.3695 | 0.2855 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0553 | 0.1353 | 0.1353 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0782 | 0.3695 | 0.3695 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0782 | 0.3695 | 0.3695 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1213 | 0.8117 | 0.8117 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0782 | 0.3695 | 0.3695 |
Leishmania major | cathepsin L-like protease | 0.0782 | 0.3695 | 0.3462 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0553 | 0.1353 | 0.3662 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1213 | 0.8117 | 0.8117 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Echinococcus granulosus | cathepsin b | 0.1397 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0782 | 0.3695 | 0.3695 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Plasmodium vivax | vivapain-2 | 0.0782 | 0.3695 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0782 | 0.3695 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Onchocerca volvulus | 0.0782 | 0.3695 | 1 | |
Onchocerca volvulus | 0.0782 | 0.3695 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0536 | 0.1176 | 0.1176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0536 | 0.1176 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0967 | 0.5597 | 0.5597 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0553 | 0.1353 | 0.1667 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0536 | 0.1176 | 0.1176 |
Brugia malayi | Cathepsin L-like precursor | 0.0782 | 0.3695 | 0.3695 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1213 | 0.8117 | 1 |
Leishmania major | cathepsin L-like protease | 0.1213 | 0.8117 | 1 |
Leishmania major | cathepsin L-like protease | 0.1213 | 0.8117 | 1 |
Onchocerca volvulus | 0.0782 | 0.3695 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0782 | 0.3695 | 0.3695 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0782 | 0.3695 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0782 | 0.3695 | 0.3695 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0782 | 0.3695 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1397 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1397 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0782 | 0.3695 | 0.3695 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0782 | 0.3695 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0782 | 0.3695 | 0.2855 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.