Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0829 | 0.4681 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0182 | 0.0956 | 0.2042 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.0085 | 0.0181 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.02 | 0.0427 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0085 | 0.0181 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0031 | 0.0085 | 0.0181 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0096 | 0.0462 | 0.0987 |
Schistosoma mansoni | gliotactin | 0.014 | 0.0714 | 0.1525 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.014 | 0.0714 | 0.1525 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0017 | 0.0036 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0025 | 0.0052 | 0.0112 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0182 | 0.0956 | 0.3362 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0539 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0714 | 0.1525 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0001 | 0.0001 |
Brugia malayi | Carboxylesterase family protein | 0.014 | 0.0714 | 0.1525 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0085 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0107 | 0.0229 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0016 | 0.0001 | 0.0003 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0189 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0055 | 0.0118 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0061 | 0.0258 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0308 | 0.1679 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.02 | 0.0427 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0189 | 0.0403 |
Wolbachia endosymbiont of Brugia malayi | replicative DNA helicase | 0.0394 | 0.2174 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0085 | 0.0181 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0016 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0001 | 0.0003 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0003 | 0.0006 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0085 | 0.0181 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0017 | 0.2122 |
Echinococcus granulosus | BC026374 protein S09 family | 0.014 | 0.0714 | 0.1525 |
Toxoplasma gondii | hypothetical protein | 0.005 | 0.0193 | 0.7474 |
Loa Loa (eye worm) | hypothetical protein | 0.0829 | 0.4681 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0308 | 0.1679 | 1 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0085 | 0.0181 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0112 | 0.024 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0031 | 0.0085 | 0.0181 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0017 | 0.0628 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0017 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.0891 | 0.1904 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0017 | 0.0036 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0085 | 0.0181 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0055 | 0.2126 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0189 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0714 | 0.1525 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0055 | 0.0327 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.019 | 0.0407 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0017 | 0.0096 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | jmjC domain containing protein | 0.0096 | 0.0462 | 0.0987 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.019 | 0.0407 |
Echinococcus granulosus | Smad4 | 0.0025 | 0.0052 | 0.0112 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.014 | 0.0714 | 0.1525 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0085 | 0.0181 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0025 | 0.0052 | 0.0112 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0736 | 0.4147 | 0.886 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0055 | 0.7189 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0516 | 0.2877 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0052 | 0.0112 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0001 | 0.0001 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0017 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0714 | 0.1525 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0714 | 0.1525 |
Onchocerca volvulus | 0.0061 | 0.0258 | 0.0694 | |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0539 | 1 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0001 | 0.0001 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.011 | 0.0539 | 0.1152 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0112 | 0.024 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.0258 | 0.0552 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0146 | 0.0746 | 0.4441 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0241 | 0.1294 | 0.2765 |
Echinococcus multilocularis | acetylcholinesterase | 0.0829 | 0.4681 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0077 | 0.0164 |
Brugia malayi | Carboxylesterase family protein | 0.014 | 0.0714 | 0.1525 |
Loa Loa (eye worm) | carboxylesterase | 0.0829 | 0.4681 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0829 | 0.4681 | 1 |
Chlamydia trachomatis | replicative DNA helicase | 0.0394 | 0.2174 | 0.5 |
Brugia malayi | hypothetical protein | 0.014 | 0.0714 | 0.1525 |
Echinococcus granulosus | acetylcholinesterase | 0.0829 | 0.4681 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.0001 | 0.0003 |
Echinococcus granulosus | acetylcholinesterase | 0.0829 | 0.4681 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0017 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.02 | 0.0427 |
Onchocerca volvulus | 0.014 | 0.0714 | 0.2438 | |
Schistosoma mansoni | microtubule-associated protein tau | 0.0736 | 0.4147 | 0.886 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0077 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.1294 | 0.2765 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0031 | 0.0085 | 0.0181 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0017 | 0.0096 |
Onchocerca volvulus | 0.014 | 0.0714 | 0.2438 | |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0001 | 0.0003 |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.0001 | 0.0003 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0077 | 0.2958 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.0891 | 0.1904 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.014 | 0.0714 | 0.0714 |
Echinococcus granulosus | neuroligin | 0.014 | 0.0714 | 0.1525 |
Treponema pallidum | replicative DNA helicase (dnaB) | 0.0394 | 0.2174 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0258 | 0.0552 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0017 | 0.0036 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0016 | 0.0001 | 0.0003 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0001 | 0.0001 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0055 | 0.0327 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0031 | 0.0085 | 0.0181 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0031 | 0.0085 | 0.0031 |
Echinococcus granulosus | carboxylesterase 5A | 0.0829 | 0.4681 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.014 | 0.0714 | 0.1525 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0241 | 0.1294 | 0.2765 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.0085 | 0.0181 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0085 | 0.0181 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0055 | 0.0327 |
Brugia malayi | Carboxylesterase family protein | 0.0829 | 0.4681 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0829 | 0.4681 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.019 | 0.0407 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0085 | 0.0181 |
Onchocerca volvulus | 0.0483 | 0.2691 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0258 | 0.0552 |
Brugia malayi | Carboxylesterase family protein | 0.014 | 0.0714 | 0.1525 |
Echinococcus multilocularis | peregrin | 0.0029 | 0.0077 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0829 | 0.4681 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0085 | 0.0181 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0025 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0001 | 0.0003 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0112 | 0.024 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0539 | 0.1152 |
Echinococcus multilocularis | smad | 0.0025 | 0.0052 | 0.0112 |
Brugia malayi | Carboxylesterase family protein | 0.014 | 0.0714 | 0.1525 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0714 | 0.1525 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0025 | 0.0052 | 0.0112 |
Onchocerca volvulus | 0.014 | 0.0714 | 0.2438 | |
Echinococcus granulosus | smad | 0.0025 | 0.0052 | 0.0112 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0473 | 0.263 | 0.5618 |
Brugia malayi | hypothetical protein | 0.0241 | 0.1294 | 0.2765 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0055 | 0.0118 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0077 | 0.0164 |
Schistosoma mansoni | jumonji domain containing protein | 0.0076 | 0.0348 | 0.0743 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0025 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0112 | 0.024 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0085 | 0.0181 |
Onchocerca volvulus | 0.014 | 0.0714 | 0.2438 | |
Schistosoma mansoni | Replicative DNA helicase | 0.0394 | 0.2174 | 0.4644 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.0085 | 0.0181 |
Echinococcus granulosus | neuropeptide s receptor | 0.0473 | 0.263 | 0.5618 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0189 | 0.0403 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | acetylcholinesterase | 0.014 | 0.0714 | 0.1525 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.011 | 0.0539 | 0.1152 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.014 | 0.0714 | 0.1525 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0096 | 0.0462 | 0.0987 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0085 | 0.0181 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0077 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0025 | 0.0052 | 0.0112 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0001 | 0.0001 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0539 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.0956 | 0.2042 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0025 | 0.0052 | 0.0112 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0017 | 0.0628 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0425 | 0.2353 | 0.5027 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0189 | 0.0403 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0085 | 0.0181 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0189 | 0.0403 |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.0258 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0189 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0714 | 0.1525 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.014 | 0.0714 | 0.2607 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0085 | 0.0181 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0736 | 0.4147 | 0.886 |
Echinococcus granulosus | peregrin | 0.0029 | 0.0077 | 0.0164 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0031 | 0.0085 | 0.0181 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0017 | 0.0036 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0077 | 0.0164 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0539 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0425 | 0.2353 | 0.5027 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0031 | 0.0085 | 0.0181 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.014 | 0.0714 | 0.2607 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0162 | 0.084 | 0.084 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0157 | 0.093 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0016 | 0.0001 | 0.0003 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0001 | 0.0003 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0473 | 0.263 | 0.5618 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0085 | 0.0181 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | MH2 domain containing protein | 0.0369 | 0.2034 | 0.4346 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.0157 | 0.093 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0077 | 0.0164 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0085 | 0.0181 |
Echinococcus multilocularis | Smad4 | 0.0025 | 0.0052 | 0.0112 |
Mycobacterium ulcerans | hypothetical protein | 0.0162 | 0.084 | 0.3819 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0258 | 0.0552 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0085 | 0.0181 |
Echinococcus granulosus | FTZ F1 alpha | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0017 | 0.0036 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0001 | 0.0003 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0146 | 0.0746 | 0.4441 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0055 | 0.0327 |
Schistosoma mansoni | coup transcription factor | 0.0031 | 0.0085 | 0.0181 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.011 | 0.0539 | 0.1152 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0001 | 0.0003 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.0001 | 0.0003 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0031 | 0.0085 | 0.0031 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0369 | 0.2034 | 0.4346 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.014 | 0.0714 | 0.3233 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0061 | 0.0258 | 0.0552 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0189 | 0.0403 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0077 | 0.2958 |
Echinococcus multilocularis | geminin | 0.0171 | 0.0891 | 0.1904 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0308 | 0.1679 | 1 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.0157 | 0.093 |
Echinococcus multilocularis | neuroligin | 0.014 | 0.0714 | 0.1525 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0198 | 0.0422 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0085 | 0.0181 |
Mycobacterium tuberculosis | RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. | 0.1359 | 0.7734 | 0.7734 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.014 | 0.0714 | 0.1525 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.014 | 0.0714 | 0.1525 |
Brugia malayi | Bromodomain containing protein | 0.0029 | 0.0077 | 0.0164 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0061 | 0.0258 | 0.0552 |
Loa Loa (eye worm) | twinkle helicase | 0.0112 | 0.0555 | 0.1186 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | hypothetical protein | 0.011 | 0.0539 | 0.1152 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0031 | 0.0085 | 0.0031 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0157 | 0.093 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0146 | 0.0746 | 0.4441 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0052 | 0.0112 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0017 | 0.0096 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0308 | 0.1679 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0025 | 0.0052 | 0.0112 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.014 | 0.0714 | 0.0714 |
Schistosoma mansoni | smad | 0.0025 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0369 | 0.2034 | 0.4346 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.014 | 0.0714 | 0.1525 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0112 | 0.024 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0053 | 0.0211 | 0.1254 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0258 | 0.0552 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0085 | 0.0181 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0143 | 0.0306 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0077 | 0.2958 |
Mycobacterium ulcerans | replicative DNA helicase DnaB | 0.0394 | 0.2174 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0077 | 0.0164 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0107 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0085 | 0.0181 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.014 | 0.0714 | 0.0714 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0085 | 0.0181 |
Trichomonas vaginalis | set domain proteins, putative | 0.0483 | 0.2691 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.014 | 0.0714 | 0.1525 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.014 | 0.0714 | 0.1525 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0085 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0085 | 0.0181 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0085 | 0.0181 |
Echinococcus granulosus | geminin | 0.0171 | 0.0891 | 0.1904 |
Brugia malayi | Smad1 | 0.0025 | 0.0052 | 0.0112 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0077 | 0.0164 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0107 | 0.0229 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0031 | 0.0085 | 0.0181 |
Onchocerca volvulus | 0.0049 | 0.019 | 0.0435 | |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0143 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0714 | 0.1525 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0085 | 0.0181 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0829 | 0.4681 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0829 | 0.4681 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.02 | 0.0427 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.0258 | 0.0552 |
Onchocerca volvulus | 0.0031 | 0.0085 | 0.0031 | |
Onchocerca volvulus | 0.014 | 0.0714 | 0.2438 | |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0052 | 0.0112 |
Schistosoma mansoni | Smad4 | 0.0025 | 0.0052 | 0.0112 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0031 | 0.0085 | 0.0181 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0055 | 0.7189 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.014 | 0.0714 | 0.1525 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0001 | 0.0001 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | carboxylesterase | 0.014 | 0.0714 | 0.1525 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0001 | 0.0003 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0077 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0085 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0061 | 0.0258 | 0.0552 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0052 | 0.0112 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0059 | 0.0245 | 0.0524 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0031 | 0.0085 | 0.0181 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0055 | 0.2126 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0052 | 0.0112 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0189 | 0.0403 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0112 | 0.024 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.014 | 0.0714 | 0.1525 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0257 | 0.0549 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0473 | 0.263 | 0.5618 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.0085 | 0.0181 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.0085 | 0.0181 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0085 | 0.0181 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0001 | 0.0001 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0085 | 0.0181 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.0085 | 0.0181 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0085 | 0.0181 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 158.4893 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.