Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.219 | 0.5 | 0.5 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.219 | 0.5 | 0.5 |
Toxoplasma gondii | fructose-bisphospatase II | 0.219 | 0.5 | 0.5 |
Leishmania major | 0.219 | 0.5 | 0.5 | |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.219 | 0.5 | 0.5 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.219 | 0.5 | 0.5 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.219 | 0.5 | 0.5 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.219 | 0.5 | 0.5 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.219 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | < 50 % | Inhibition against HIV-1 integrase at 1 mM | ChEMBL. | 10841789 |
Inhibition (binding) | < 50 % | Inhibition against HIV-1 integrase at 200 microM | ChEMBL. | 10841789 |
Inhibition (binding) | < 50 % | Inhibition against HIV-1 integrase at 1 mM | ChEMBL. | 10841789 |
Inhibition (binding) | < 50 % | Inhibition against HIV-1 integrase at 200 microM | ChEMBL. | 10841789 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.