Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0051 | 0.0641 | 0.1004 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0099 | 0.2735 | 0.4285 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0162 | 0.5444 | 0.8531 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.6027 | 0.6027 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0412 | 0.0645 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.5444 | 0.8531 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0412 | 0.0645 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2181 | 0.2181 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0412 | 0.0645 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.6027 | 0.6027 |
Brugia malayi | PHD-finger family protein | 0.0056 | 0.0871 | 0.0871 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.3575 | 0.3575 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0081 | 0.1943 | 0.3045 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0038 | 0.0107 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.5329 | 0.5329 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0051 | 0.0641 | 0.1004 |
Brugia malayi | Bromodomain containing protein | 0.0086 | 0.2174 | 0.2174 |
Brugia malayi | Bromodomain containing protein | 0.0169 | 0.5745 | 0.5745 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.6382 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0134 | 0.4256 | 0.6669 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.447 | 0.7004 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0081 | 0.1943 | 0.3045 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0099 | 0.2735 | 0.4285 |
Loa Loa (eye worm) | bromodomain containing protein | 0.004 | 0.0166 | 0.0166 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0066 | 0.1306 | 0.2047 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0046 | 0.0455 | 0.0455 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0099 | 0.2735 | 0.4285 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0267 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0066 | 0.1306 | 0.2047 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0099 | 0.2735 | 0.4285 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.0099 | 0.2735 | 0.4285 |
Brugia malayi | Melibiase family protein | 0.0066 | 0.1306 | 0.1306 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0412 | 0.0412 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0038 | 0.0107 | 0.0167 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 1 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0051 | 0.0641 | 0.1004 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0099 | 0.2735 | 0.4285 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0134 | 0.4256 | 0.6669 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0 | 0.5 |
Toxoplasma gondii | melibiase subfamily protein | 0.0099 | 0.2735 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0162 | 0.5444 | 0.8531 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0185 | 0.6436 | 0.6436 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0038 | 0.0107 | 0.0167 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.6382 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0162 | 0.5444 | 0.5444 |
Echinococcus multilocularis | geminin | 0.0183 | 0.6382 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.6027 | 0.6027 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0412 | 0.0645 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0038 | 0.0107 | 0.0167 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.3575 | 0.3575 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.6027 | 0.6027 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0099 | 0.2735 | 0.4285 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2597 | 0.2597 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0044 | 0.0352 | 0.0552 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0038 | 0.0107 | 0.0167 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0175 | 0.6027 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0412 | 0.0645 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0412 | 0.0412 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.6027 | 0.6027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.6027 | 0.6027 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0412 | 0.0645 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0038 | 0.0107 | 0.0167 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0162 | 0.5444 | 0.5444 |
Schistosoma mansoni | bromodomain containing protein | 0.0142 | 0.4604 | 0.7215 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0412 | 0.0645 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0066 | 0.1306 | 0.1306 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0185 | 0.6436 | 0.6436 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 1 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.8313 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.6027 | 0.6027 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.3575 | 0.3575 |
Echinococcus multilocularis | zinc finger protein | 0.0044 | 0.0352 | 0.0552 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0455 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1306 | 0.1306 |
Echinococcus granulosus | geminin | 0.0183 | 0.6382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.2411 | 0.2411 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0038 | 0.0107 | 0.0167 |
Echinococcus granulosus | zinc finger protein | 0.0044 | 0.0352 | 0.0552 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0038 | 0.0107 | 0.0167 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.447 | 0.7004 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.