Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1623 | 0.1623 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0238 | 0.1623 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1408 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1623 | 0.1623 |
Onchocerca volvulus | 0.0238 | 0.1623 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.1408 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0011 | 0.000000026186 | 0.000000026186 |
Onchocerca volvulus | 0.0238 | 0.1623 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.1408 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1408 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.1408 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0238 | 0.1623 | 0.1623 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0238 | 0.1623 | 0.5 |
Schistosoma mansoni | acetylcholinesterase | 0.0238 | 0.1623 | 0.1623 |
Echinococcus multilocularis | acetylcholinesterase | 0.1408 | 1 | 1 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0011 | 0.000000026186 | 0.000000026186 |
Echinococcus granulosus | neuroligin | 0.0238 | 0.1623 | 0.1623 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0349 | 0.2417 | 0.2417 |
Brugia malayi | Carboxylesterase family protein | 0.0238 | 0.1623 | 0.1623 |
Loa Loa (eye worm) | carboxylesterase | 0.0238 | 0.1623 | 0.1623 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0238 | 0.1623 | 0.1623 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1408 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0238 | 0.1623 | 0.1623 |
Loa Loa (eye worm) | hypothetical protein | 0.1408 | 1 | 1 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0349 | 0.2417 | 0.2417 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0238 | 0.1623 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0238 | 0.1623 | 0.1623 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0238 | 0.1623 | 0.1623 |
Brugia malayi | Carboxylesterase family protein | 0.0238 | 0.1623 | 0.1623 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0238 | 0.1623 | 0.1623 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.036 | 0.2497 | 0.2497 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0238 | 0.1623 | 0.1623 |
Echinococcus granulosus | acetylcholinesterase | 0.1408 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0238 | 0.1623 | 0.1623 |
Onchocerca volvulus | 0.0238 | 0.1623 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1623 | 0.1623 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1623 | 0.1623 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0238 | 0.1623 | 0.1623 |
Echinococcus granulosus | ankyrin repeat protein | 0.0349 | 0.2417 | 0.2417 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1408 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0238 | 0.1623 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0238 | 0.1623 | 0.1623 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0238 | 0.1623 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0238 | 0.1623 | 0.1623 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1623 | 0.1623 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0238 | 0.1623 | 0.1623 |
Brugia malayi | Carboxylesterase family protein | 0.0238 | 0.1623 | 0.1623 |
Onchocerca volvulus | 0.0238 | 0.1623 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1623 | 0.1623 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0359 | 0.2493 | 0.2493 |
Echinococcus granulosus | carboxylesterase 5A | 0.1408 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0238 | 0.1623 | 0.5 |
Onchocerca volvulus | 0.0238 | 0.1623 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.1623 | 0.1623 |
Brugia malayi | Carboxylesterase family protein | 0.0238 | 0.1623 | 0.1623 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0238 | 0.1623 | 0.1623 |
Brugia malayi | hypothetical protein | 0.0238 | 0.1623 | 0.1623 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0238 | 0.1623 | 0.1623 |
Brugia malayi | Carboxylesterase family protein | 0.1408 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.