Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0042 | 0.0064 | 0.0064 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0219 | 0.0561 | 0.0561 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0095 | 0.0214 | 0.6017 |
Entamoeba histolytica | hypothetical protein | 0.0146 | 0.0355 | 1 |
Brugia malayi | hypothetical protein | 0.0228 | 0.0587 | 0.0587 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0095 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0052 | 0.0052 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0049 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | TAR-binding protein | 0.0202 | 0.0512 | 0.0512 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0299 | 0.0299 |
Onchocerca volvulus | 0.0037 | 0.0052 | 0.0147 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0052 | 0.0111 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0029 | 0.0029 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0041 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0299 | 0.0299 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0052 | 0.0052 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0312 | 0.0822 | 0.0822 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0146 | 0.0355 | 0.0355 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0165 | 0.041 | 0.041 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0046 | 0.0046 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.004 | 0.0061 | 0.0061 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.3594 | 1 | 1 |
Leishmania major | mitochondrial DNA polymerase beta | 0.029 | 0.0758 | 0.0758 |
Onchocerca volvulus | 0.0126 | 0.0299 | 0.105 | |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0169 | 0.0419 | 0.0419 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0052 | 0.0111 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0049 | 0.0085 | 0.2836 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0127 | 0.0127 |
Echinococcus multilocularis | acetylcholinesterase | 0.0744 | 0.2029 | 0.2029 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0241 | 0.0622 | 0.0622 |
Schistosoma mansoni | tar DNA-binding protein | 0.0202 | 0.0512 | 0.0512 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.004 | 0.0061 | 0.0061 |
Schistosoma mansoni | tyrosine kinase | 0.0042 | 0.0064 | 0.0064 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0536 | 0.1445 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.003 | 0.003 | 0.003 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0126 | 0.0299 | 0.0299 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0012 | 0.0012 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0019 | 0.004 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0126 | 0.0299 | 0.0299 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0048 | 0.0103 |
Loa Loa (eye worm) | glutamate receptor | 0.0042 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0202 | 0.0512 | 0.0512 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.0302 | 0.1061 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.003 | 0.003 | 0.003 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0023 | 0.0013 | 0.0367 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0355 | 0.0355 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.021 | 0.021 |
Schistosoma mansoni | tyrosine kinase | 0.0042 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | carboxylesterase | 0.0126 | 0.0299 | 0.0299 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0012 | 0.0329 |
Schistosoma mansoni | patched 1 | 0.152 | 0.42 | 0.42 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0023 | 0.0013 | 0.0433 |
Entamoeba histolytica | hypothetical protein | 0.0146 | 0.0355 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0064 | 0.0127 | 0.0127 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0046 | 0.0076 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0095 | 0.0214 | 0.0214 |
Trichomonas vaginalis | conserved hypothetical protein | 0.152 | 0.42 | 0.9007 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0126 | 0.0299 | 0.0299 |
Echinococcus multilocularis | lamin | 0.0086 | 0.0188 | 0.0188 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0012 | 0.0329 |
Echinococcus multilocularis | neuropeptide s receptor | 0.048 | 0.129 | 0.129 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.003 | 0.003 | 0.003 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0023 | 0.0013 | 0.0013 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0165 | 0.041 | 0.041 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0241 | 0.0622 | 0.0622 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0165 | 0.041 | 0.041 |
Brugia malayi | Carboxylesterase family protein | 0.0126 | 0.0299 | 0.0299 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.007 | 0.0144 | 0.0144 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.004 | 0.0061 | 0.1705 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0126 | 0.0299 | 0.2071 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0042 | 0.0064 | 0.0064 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.1616 | 0.4466 | 0.4466 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0095 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0744 | 0.2029 | 0.2029 |
Brugia malayi | Heterochromatin protein 1 | 0.0064 | 0.0127 | 0.0127 |
Onchocerca volvulus | 0.0126 | 0.0299 | 0.105 | |
Onchocerca volvulus | 0.0037 | 0.0052 | 0.0147 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | carboxylesterase | 0.0126 | 0.0299 | 0.0299 |
Echinococcus multilocularis | geminin | 0.039 | 0.1039 | 0.1039 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.0587 | 0.0587 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0052 | 0.0359 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0126 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0299 | 0.0299 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0049 | 0.0085 | 0.0085 |
Toxoplasma gondii | NAC domain-containing protein | 0.004 | 0.0061 | 0.2013 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0041 | 0.0061 | 0.0423 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0012 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0058 | 0.0058 |
Brugia malayi | Carboxylesterase family protein | 0.0126 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | inositol-1 | 0.0082 | 0.0176 | 0.0176 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0137 | 0.033 | 0.033 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.152 | 0.42 | 0.42 |
Echinococcus multilocularis | Ribosomal protein S1, RNA binding domain | 0.0081 | 0.0174 | 0.0174 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0081 | 0.0174 | 0.0174 |
Schistosoma mansoni | thyroid hormone receptor | 0.013 | 0.0312 | 0.0312 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0126 | 0.0299 | 0.0299 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Echinococcus granulosus | geminin | 0.039 | 0.1039 | 0.1039 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.0085 | 0.0085 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0082 | 0.0176 | 0.0377 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0023 | 0.0013 | 0.0013 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0042 | 0.0064 | 0.0064 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0082 | 0.0176 | 0.0176 |
Echinococcus granulosus | chromobox protein 1 | 0.0064 | 0.0127 | 0.0127 |
Schistosoma mansoni | glutamate receptor kainate | 0.0219 | 0.0561 | 0.0561 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0042 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | metabotropic glutamate receptor 8 | 0.0042 | 0.0064 | 0.0064 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0081 | 0.0174 | 0.0174 |
Mycobacterium ulcerans | oxidoreductase | 0.0041 | 0.0061 | 0.0061 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0238 | 0.0614 | 0.4245 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0039 | 0.0057 | 0.0057 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0012 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0208 | 0.0208 |
Leishmania major | basic transcription factor 3a, putative | 0.004 | 0.0061 | 0.0061 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0052 | 0.1738 |
Echinococcus multilocularis | 0.0041 | 0.0061 | 0.0061 | |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0137 | 0.033 | 0.033 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0241 | 0.0622 | 0.0622 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.0419 | 0.0419 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0042 | 0.0064 | 0.0064 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0126 | 0.0299 | 0.0642 |
Brugia malayi | Bromodomain containing protein | 0.0088 | 0.0193 | 0.0193 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.029 | 0.0758 | 0.0758 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0012 | 0.0081 |
Echinococcus granulosus | Protein patched homolog 1 | 0.152 | 0.42 | 0.42 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0126 | 0.0301 | 0.0301 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.003 | 0.003 | 0.003 |
Brugia malayi | chromobox protein homolog 3 | 0.0036 | 0.0048 | 0.0048 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0029 | 0.4727 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0041 | 0.0061 | 0.0061 |
Echinococcus granulosus | lamin | 0.0086 | 0.0188 | 0.0188 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0041 | 0.0061 | 0.2031 |
Onchocerca volvulus | 0.0137 | 0.033 | 0.1163 | |
Echinococcus multilocularis | glutamate receptor 2 | 0.018 | 0.045 | 0.045 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0094 | 0.021 | 0.021 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0023 | 0.0013 | 0.0013 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0041 | 0.0061 | 0.3528 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0061 | 0.0061 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0052 | 0.0052 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0023 | 0.0013 | 0.0028 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0012 | 0.0012 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0573 | 0.1551 | 0.1551 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.013 | 0.0312 | 0.0312 |
Schistosoma mansoni | amine oxidase | 0.0041 | 0.0061 | 0.0061 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.048 | 0.129 | 0.129 |
Echinococcus granulosus | carboxylesterase 5A | 0.0744 | 0.2029 | 0.2029 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0081 | 0.0174 | 0.0174 |
Brugia malayi | Latrophilin receptor protein 2 | 0.003 | 0.003 | 0.003 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.003 | 0.003 | 0.003 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0081 | 0.0174 | 0.0174 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0241 | 0.0622 | 0.0622 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0042 | 0.0064 | 0.0064 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0219 | 0.0561 | 0.0561 |
Echinococcus multilocularis | chromobox protein 1 | 0.0064 | 0.0127 | 0.0127 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0039 | 0.0057 | 0.0057 |
Brugia malayi | Inositol-1 | 0.0082 | 0.0176 | 0.0176 |
Onchocerca volvulus | 0.0037 | 0.0052 | 0.0147 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.152 | 0.42 | 0.42 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0082 | 0.0176 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Schistosoma mansoni | inositol monophosphatase | 0.0082 | 0.0176 | 0.0176 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0012 | 0.0012 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0261 | 0.0677 | 0.0677 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0052 | 0.1473 |
Entamoeba histolytica | hypothetical protein | 0.0146 | 0.0355 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0153 | 0.0374 | 0.0374 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0219 | 0.0561 | 0.0561 |
Schistosoma mansoni | gliotactin | 0.0126 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | intermediate filament protein | 0.0086 | 0.0188 | 0.0188 |
Entamoeba histolytica | hypothetical protein | 0.0146 | 0.0355 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0094 | 0.021 | 0.021 |
Echinococcus multilocularis | transcription factor btf3 | 0.004 | 0.0061 | 0.0061 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.0622 | 0.0622 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0058 | 0.0058 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0126 | 0.0301 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0052 | 0.0092 | 0.0092 |
Onchocerca volvulus | 0.0041 | 0.0061 | 0.018 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0144 | 0.0144 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0073 | 0.0152 | 0.105 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0299 | 0.0299 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.003 | 0.003 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0049 | 0.0085 | 0.0085 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0049 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0064 | 0.0127 | 0.0127 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0052 | 0.0112 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0041 | 0.0061 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0202 | 0.0512 | 0.0512 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0041 | 0.0061 | 0.2031 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0744 | 0.2029 | 0.2029 |
Brugia malayi | MAP kinase sur-1 | 0.0049 | 0.0085 | 0.0085 |
Trypanosoma cruzi | ISWI complex protein | 0.0035 | 0.0046 | 0.0046 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0041 | 0.0061 | 0.2031 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.0085 | 0.0085 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0153 | 0.0374 | 0.259 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0052 | 0.0092 | 0.0092 |
Echinococcus granulosus | glutamate receptor 2 | 0.0261 | 0.0677 | 0.0677 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0261 | 0.0677 | 0.0677 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0299 | 0.0299 |
Echinococcus multilocularis | acetylcholinesterase | 0.0744 | 0.2029 | 0.2029 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0041 | 0.0061 | 1 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0219 | 0.0561 | 0.0561 |
Trypanosoma cruzi | extracellular receptor, putative | 0.0042 | 0.0064 | 0.0064 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0036 | 0.0048 | 0.0133 |
Mycobacterium ulcerans | dehydrogenase | 0.0041 | 0.0061 | 0.0061 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0667 | 0.1812 | 0.1812 |
Schistosoma mansoni | hypothetical protein | 0.0121 | 0.0285 | 0.0285 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.003 | 0.003 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.3594 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0126 | 0.0299 | 0.0299 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0299 | 0.0299 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0085 | 0.0183 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.152 | 0.42 | 0.42 |
Trypanosoma brucei | ISWI complex protein | 0.0035 | 0.0046 | 0.0046 |
Brugia malayi | Pre-SET motif family protein | 0.088 | 0.241 | 0.241 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0012 | 0.0012 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0052 | 0.0112 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0052 | 0.0052 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0137 | 0.0331 | 0.0331 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0082 | 0.0176 | 0.0176 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0261 | 0.0677 | 0.0677 |
Trichomonas vaginalis | chromobox protein, putative | 0.0039 | 0.0056 | 0.0119 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0041 | 0.0061 | 0.2031 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0061 | 0.0061 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0046 | 0.0076 | 0.0076 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0049 | 0.0085 | 0.0085 |
Echinococcus granulosus | Ribosomal protein S1 RNA binding domain | 0.0081 | 0.0174 | 0.0174 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.152 | 0.42 | 0.42 |
Loa Loa (eye worm) | carboxylesterase | 0.0744 | 0.2029 | 0.2029 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0183 | 0.0183 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0023 | 0.0013 | 0.0433 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0261 | 0.0677 | 0.0677 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0241 | 0.0622 | 0.0622 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0052 | 0.1724 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0126 | 0.0299 | 0.0299 |
Trichomonas vaginalis | chromobox protein, putative | 0.0064 | 0.0127 | 0.0272 |
Schistosoma mansoni | alpha-glucosidase | 0.0145 | 0.0354 | 0.0354 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.1686 | 0.4664 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0061 | 0.2031 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0042 | 0.0064 | 0.0064 |
Echinococcus multilocularis | GPCR, family 2 | 0.003 | 0.003 | 0.003 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0261 | 0.0677 | 0.0677 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0219 | 0.0561 | 0.0561 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0081 | 0.0081 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0126 | 0.0299 | 0.0299 |
Brugia malayi | CHE-14 protein | 0.152 | 0.42 | 0.42 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0037 | 0.0052 | 0.0052 |
Onchocerca volvulus | 0.0086 | 0.0188 | 0.0642 | |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.003 | 0.003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0019 | 0.004 |
Onchocerca volvulus | 0.0042 | 0.0064 | 0.0191 | |
Brugia malayi | hypothetical protein | 0.0126 | 0.0299 | 0.0299 |
Plasmodium vivax | SET domain protein, putative | 0.0126 | 0.0301 | 1 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.3594 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0082 | 0.0178 | 0.0178 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.3594 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.013 | 0.0312 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0302 | 0.0302 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0052 | 0.0359 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0122 | 0.0288 | 0.0288 |
Echinococcus multilocularis | chromobox protein 1 | 0.0064 | 0.0127 | 0.0127 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0049 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0042 | 0.0064 | 0.0064 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0041 | 0.0062 | 0.0062 |
Schistosoma mansoni | tar DNA-binding protein | 0.0202 | 0.0512 | 0.0512 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0012 | 0.0012 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0052 | 0.0111 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0052 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.0744 | 0.2029 | 0.2029 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.0085 | 0.0085 |
Brugia malayi | PHD-finger family protein | 0.0057 | 0.0107 | 0.0107 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.007 | 0.0144 | 0.0144 |
Schistosoma mansoni | hypothetical protein | 0.039 | 0.1039 | 0.1039 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.007 | 0.0144 | 0.0994 |
Schistosoma mansoni | protein kinase | 0.0042 | 0.0064 | 0.0064 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.0622 | 0.0622 |
Trichomonas vaginalis | chromobox protein, putative | 0.0039 | 0.0056 | 0.0119 |
Onchocerca volvulus | 0.0086 | 0.0188 | 0.0642 | |
Leishmania major | UDP-galactopyranose mutase | 0.0041 | 0.0061 | 0.0061 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.3594 | 1 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0052 | 0.0111 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0052 | 0.0111 |
Trichomonas vaginalis | set domain proteins, putative | 0.1002 | 0.275 | 0.5898 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.0622 | 0.0622 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.1686 | 0.4664 | 1 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0023 | 0.0013 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0078 | 0.0078 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0052 | 0.0052 |
Echinococcus granulosus | zinc finger protein | 0.0045 | 0.0073 | 0.0073 |
Echinococcus granulosus | expressed conserved protein | 0.0089 | 0.0198 | 0.0198 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0041 | 0.0061 | 0.0061 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0049 | 0.0085 | 0.0085 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0052 | 0.0052 |
Trypanosoma brucei | glucosidase, putative | 0.0037 | 0.0052 | 0.0052 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0052 | 0.0052 |
Schistosoma mansoni | intermediate filament proteins | 0.0086 | 0.0188 | 0.0188 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0041 | 0.0061 | 0.0061 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0052 | 0.0052 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0052 | 0.1724 |
Schistosoma mansoni | zinc finger protein | 0.0035 | 0.0046 | 0.0046 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0042 | 0.0064 | 0.0064 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0354 | 0.0938 | 0.0938 |
Brugia malayi | Carboxylesterase family protein | 0.0744 | 0.2029 | 0.2029 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0667 | 0.1812 | 0.1812 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0052 | 0.2869 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0086 | 0.0188 | 0.0188 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.004 | 0.0061 | 0.2013 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0121 | 0.0285 | 0.0285 |
Trichomonas vaginalis | chromobox protein, putative | 0.0064 | 0.0127 | 0.0272 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.003 | 0.003 | 0.003 |
Schistosoma mansoni | chromobox protein | 0.0064 | 0.0127 | 0.0127 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0228 | 0.0587 | 0.0587 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0052 | 0.0092 | 0.0092 |
Schistosoma mansoni | acetylcholinesterase | 0.0126 | 0.0299 | 0.0299 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0082 | 0.0176 | 0.0176 |
Echinococcus granulosus | neuroligin | 0.0126 | 0.0299 | 0.0299 |
Brugia malayi | Carboxylesterase family protein | 0.0126 | 0.0299 | 0.0299 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0023 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0012 | 0.0012 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0144 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0048 | 0.0048 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0041 | 0.0061 | 0.0423 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0052 | 0.0359 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0052 | 0.0052 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0037 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0214 | 0.0214 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0041 | 0.0061 | 0.0061 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0000080642 | 0.0000080642 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0744 | 0.2029 | 0.2029 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0012 | 0.0012 |
Echinococcus multilocularis | musashi | 0.0086 | 0.0188 | 0.0188 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0082 | 0.0176 | 0.0176 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0037 | 0.0052 | 0.0112 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0603 | 0.1635 | 0.1635 |
Trichomonas vaginalis | chaperonin, putative | 0.0023 | 0.0013 | 0.0028 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0052 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0087 | 0.0087 |
Echinococcus granulosus | tyrosine kinase | 0.0042 | 0.0064 | 0.0064 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0228 | 0.0587 | 0.0587 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0061 | 0.2031 |
Toxoplasma gondii | hypothetical protein | 0.0047 | 0.0078 | 0.2603 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0576 | 0.1559 | 0.1559 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0042 | 0.0064 | 0.0064 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0042 | 0.0064 | 0.0064 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0052 | 0.0359 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0394 | 0.1049 | 0.1049 |
Schistosoma mansoni | tar DNA-binding protein | 0.0202 | 0.0512 | 0.0512 |
Brugia malayi | Carboxylesterase family protein | 0.0126 | 0.0299 | 0.0299 |
Echinococcus granulosus | intermediate filament protein | 0.0086 | 0.0188 | 0.0188 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Echinococcus multilocularis | protein patched | 0.152 | 0.42 | 0.42 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0012 | 0.0012 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0085 | 0.0183 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0165 | 0.041 | 0.041 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0029 | 0.0029 |
Schistosoma mansoni | inositol monophosphatase | 0.0082 | 0.0176 | 0.0176 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.0144 | 0.0144 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0078 | 0.0078 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0029 | 0.0029 |
Trypanosoma cruzi | ISWI complex protein | 0.0035 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0219 | 0.0561 | 0.0561 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0046 | 0.0046 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0061 | 0.0061 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0041 | 0.0061 | 0.0061 |
Echinococcus multilocularis | NMDA receptor | 0.0081 | 0.0174 | 0.0174 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0085 | 0.0183 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0085 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.0062 | 0.0062 |
Schistosoma mansoni | glutamate receptor kainate | 0.0219 | 0.0561 | 0.0561 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0042 | 0.0064 | 0.0064 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0126 | 0.0299 | 0.0299 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0193 | 0.0193 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0023 | 0.0013 | 0.2133 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0064 | 0.0127 | 0.0127 |
Brugia malayi | Pre-SET motif family protein | 0.0126 | 0.0301 | 0.0301 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0049 | 0.0085 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0042 | 0.0064 | 0.0064 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0126 | 0.0299 | 0.0299 |
Onchocerca volvulus | 0.0042 | 0.0064 | 0.0191 | |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0052 | 0.0052 |
Schistosoma mansoni | hypothetical protein | 0.039 | 0.1039 | 0.1039 |
Schistosoma mansoni | tar DNA-binding protein | 0.0202 | 0.0512 | 0.0512 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0146 | 0.0355 | 0.0355 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0023 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.0047 | 0.0078 | 0.0242 | |
Brugia malayi | SWIRM domain containing protein | 0.0041 | 0.0061 | 0.0061 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0126 | 0.0299 | 0.2071 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Echinococcus multilocularis | tar DNA binding protein | 0.0202 | 0.0512 | 0.0512 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0202 | 0.0512 | 0.0512 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0023 | 0.0013 | 0.0013 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0082 | 0.0176 | 0.0176 |
Onchocerca volvulus | 0.0028 | 0.0026 | 0.0054 | |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0029 | 0.096 |
Echinococcus multilocularis | zinc finger protein | 0.0045 | 0.0073 | 0.0073 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0121 | 0.0285 | 0.0285 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0052 | 0.0052 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.029 | 0.0758 | 0.0758 |
Echinococcus granulosus | lamin dm0 | 0.0086 | 0.0188 | 0.0188 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0126 | 0.0301 | 0.0301 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.0419 | 0.0419 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0082 | 0.0176 | 0.4946 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.3594 | 1 | 1 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.3594 | 1 | 1 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0023 | 0.0013 | 0.0013 |
Echinococcus multilocularis | expressed conserved protein | 0.0089 | 0.0198 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0052 | 0.0052 |
Schistosoma mansoni | bromodomain containing protein | 0.0145 | 0.0353 | 0.0353 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0039 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0026 | 0.0026 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0603 | 0.1635 | 0.1635 |
Onchocerca volvulus | 0.0126 | 0.0299 | 0.105 | |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0052 | 0.0052 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0082 | 0.0176 | 0.5838 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0052 | 0.0359 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0126 | 0.0299 | 0.0299 |
Brugia malayi | beta-NAC-like protein | 0.004 | 0.0061 | 0.0061 |
Echinococcus granulosus | neuropeptide s receptor | 0.048 | 0.129 | 0.129 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0261 | 0.0677 | 0.0677 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0029 | 0.0029 |
Onchocerca volvulus | 0.1002 | 0.275 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0063 | 0.0063 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0126 | 0.0299 | 0.0642 |
Echinococcus multilocularis | tyrosine kinase | 0.0042 | 0.0064 | 0.0064 |
Echinococcus granulosus | tar DNA binding protein | 0.0202 | 0.0512 | 0.0512 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0029 | 0.4727 |
Echinococcus granulosus | atrial natriuretic peptide receptor | 0.0042 | 0.0064 | 0.0064 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0146 | 0.0355 | 0.0355 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0041 | 0.0061 | 0.5 |
Schistosoma mansoni | lamin | 0.0086 | 0.0188 | 0.0188 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0037 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0012 | 0.0012 |
Echinococcus granulosus | acetylcholinesterase | 0.0744 | 0.2029 | 0.2029 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0394 | 0.1049 | 0.1049 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0012 | 0.0012 |
Schistosoma mansoni | alpha-glucosidase | 0.0145 | 0.0354 | 0.0354 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0081 | 0.0174 | 0.0174 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0061 | 0.013 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.004 | 0.0061 | 0.991 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0052 | 0.0359 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0049 | 0.0085 | 0.0085 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0012 | 0.0012 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0042 | 0.0064 | 0.0064 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0012 | 0.0081 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0082 | 0.0176 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.0144 | 0.0144 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0052 | 0.0052 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0137 | 0.0331 | 0.0331 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0241 | 0.0622 | 0.0622 |
Schistosoma mansoni | tar DNA-binding protein | 0.0202 | 0.0512 | 0.0512 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0012 | 0.0012 |
Schistosoma mansoni | chromobox protein | 0.0064 | 0.0127 | 0.0127 |
Schistosoma mansoni | glutamate receptor kainate | 0.0219 | 0.0561 | 0.0561 |
Echinococcus multilocularis | protein dispatched 1 | 0.1526 | 0.4216 | 0.4216 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.0302 | 0.1061 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.008 | 0.008 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0081 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0061 | 0.0061 |
Onchocerca volvulus | 0.0048 | 0.0081 | 0.0254 | |
Brugia malayi | T-complex protein 1, beta subunit | 0.0023 | 0.0013 | 0.0013 |
Schistosoma mansoni | lamin | 0.0086 | 0.0188 | 0.0188 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0061 | 0.013 |
Schistosoma mansoni | zinc finger protein | 0.0045 | 0.0073 | 0.0073 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0062 | 0.0062 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.007 | 0.0144 | 0.4778 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0144 | 0.0144 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0667 | 0.1812 | 0.1812 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0052 | 0.0052 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0137 | 0.033 | 0.033 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0061 | 0.1705 |
Echinococcus granulosus | acetylcholinesterase | 0.0744 | 0.2029 | 0.2029 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0059 | 0.0059 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0073 | 0.0152 | 1 |
Echinococcus multilocularis | neuroligin | 0.0126 | 0.0299 | 0.0299 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.048 | 0.129 | 0.129 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0058 | 0.0058 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0169 | 0.0419 | 0.0419 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.3594 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0126 | 0.0299 | 0.2071 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0041 | 0.0061 | 0.0061 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0783 | 0.2139 | 0.2139 |
Brugia malayi | hypothetical protein | 0.0146 | 0.0355 | 0.0355 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0052 | 0.0052 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0049 | 0.0085 | 0.0085 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0023 | 0.0013 | 0.0013 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0052 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0081 | 0.0081 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0041 | 0.0063 | 0.0063 |
Brugia malayi | hypothetical protein | 0.0127 | 0.0302 | 0.0302 |
Brugia malayi | Bromodomain containing protein | 0.0172 | 0.0428 | 0.0428 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0042 | 0.0064 | 0.0064 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.003 | 0.003 | 0.003 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0047 | 0.008 | 0.008 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0052 | 0.0112 |
Echinococcus multilocularis | atrial natriuretic peptide receptor | 0.0042 | 0.0064 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0059 | 0.0059 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0012 | 0.0012 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0137 | 0.0331 | 0.0331 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.003 | 0.003 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0082 | 0.0176 | 0.0176 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0037 | 0.0052 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Trypanosoma brucei | protein kinase, putative | 0.0049 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0061 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.0174 | 0.0174 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0052 | 0.2869 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0058 | 0.0058 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0061 | 0.013 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0219 | 0.0561 | 0.0561 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0064 | 0.18 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0042 | 0.0064 | 0.0064 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.007 | 0.0144 | 0.0144 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0354 | 0.0938 | 0.0938 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0261 | 0.0677 | 0.0677 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0023 | 0.0013 | 0.0028 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0169 | 0.0419 | 0.0419 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0041 | 0.0061 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0056 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0302 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.04 | 0.04 |
Leishmania major | extracellular receptor, putative | 0.0042 | 0.0064 | 0.0064 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0012 | 0.0012 |
Echinococcus multilocularis | tumor protein p63 | 0.0326 | 0.0861 | 0.0861 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0041 | 0.0063 | 0.0063 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0094 | 0.021 | 0.021 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0052 | 0.0359 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0219 | 0.0561 | 0.0561 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0029 | 0.096 |
Onchocerca volvulus | 0.0126 | 0.0299 | 0.105 | |
Schistosoma mansoni | transcription factor btf3 | 0.004 | 0.0061 | 0.0061 |
Schistosoma mansoni | amine oxidase | 0.0041 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0042 | 0.0064 | 0.0064 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0012 | 0.0012 |
Brugia malayi | intermediate filament protein | 0.0086 | 0.0188 | 0.0188 |
Onchocerca volvulus | Atrial natriuretic peptide receptor 3 homolog | 0.0042 | 0.0064 | 0.0191 |
Brugia malayi | Guanylyl cyclase protein 23 | 0.0042 | 0.0064 | 0.0064 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0082 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.003 | 0.003 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0041 | 0.0061 | 0.0061 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0082 | 0.0176 | 0.0377 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0082 | 0.0176 | 0.0377 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0042 | 0.0064 | 0.0064 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0041 | 0.0061 | 0.0061 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0041 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0052 | 0.0052 |
Mycobacterium ulcerans | monoamine oxidase | 0.0041 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.041 | 0.041 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0062 | 0.0062 |
Brugia malayi | TAR-binding protein | 0.0202 | 0.0512 | 0.0512 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.029 | 0.0758 | 0.0758 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0052 | 0.0052 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0078 | 0.0078 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0052 | 0.1473 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.1686 | 0.4664 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0188 | 0.0188 |
Onchocerca volvulus | 0.0098 | 0.022 | 0.0762 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0126 | 0.0299 | 0.0299 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0052 | 0.0052 |
Brugia malayi | Carboxylesterase family protein | 0.0744 | 0.2029 | 0.2029 |
Loa Loa (eye worm) | bromodomain containing protein | 0.004 | 0.0061 | 0.0061 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0261 | 0.0677 | 0.0677 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.005 | 0.0086 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0261 | 0.0677 | 0.0677 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0312 | 0.0822 | 0.0822 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0052 | 0.0052 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0603 | 0.1635 | 0.1635 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0086 | 0.0188 | 0.0188 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.088 | 0.241 | 0.241 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0052 | 0.0111 |
Echinococcus multilocularis | lamin dm0 | 0.0086 | 0.0188 | 0.0188 |
Onchocerca volvulus | 0.0126 | 0.0299 | 0.105 | |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0049 | 0.0085 | 0.0085 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.1616 | 0.4466 | 0.4466 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0052 | 0.0052 |
Echinococcus granulosus | transcription factor btf3 | 0.004 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0127 | 0.0127 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.1686 | 0.4664 | 1 |
Loa Loa (eye worm) | ICD-1 protein | 0.004 | 0.0061 | 0.0061 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.1576 | 0.4356 | 0.4356 |
Echinococcus granulosus | glutamate receptor 2 | 0.018 | 0.045 | 0.045 |
Echinococcus granulosus | tumor protein p63 | 0.0326 | 0.0861 | 0.0861 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0023 | 0.0013 | 0.0013 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0744 | 0.2029 | 0.2029 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.004 | 0.0061 | 0.0061 |
Brugia malayi | RNA binding protein | 0.0202 | 0.0512 | 0.0512 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0048 | 0.0103 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0576 | 0.1559 | 0.1559 |
Loa Loa (eye worm) | hypothetical protein | 0.3594 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0064 | 0.0064 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0039 | 0.0057 | 0.0057 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 0.021 ug ml-1 | Cytotoxic activity against murine P388 leukemia cells | ChEMBL. | 15056007 |
Solubility | = 19.8 mg ml-1 | Solubility of the compound was determined at pH 7.2 | ChEMBL. | 15056007 |
T/C (functional) | = 125 % | Ratio of median survival time of treated mice (T) to that of median survival time of controls (C) in mice infected with p388 cells (in vivo) at a dose of 0.78 mg/kg | ChEMBL. | 15056007 |
T/C (functional) | = 125 % | Ratio of median survival time of treated mice (T) to that of median survival time of controls (C) in mice infected with p388 cells (in vivo) at a dose of 1.56 mg/kg | ChEMBL. | 15056007 |
T/C (functional) | = 163 % | Ratio of median survival time of treated mice (T) to that of median survival time of controls (C) in mice infected with p388 cells (in vivo) at a dose of 3.13 mg/kg | ChEMBL. | 15056007 |
T/C (functional) | = 188 % | Ratio of median survival time of treated mice (T) to that of median survival time of controls (C) in mice infected with p388 cells (in vivo) at a dose of 6.25 mg/kg | ChEMBL. | 15056007 |
T/C (functional) | = 238 % | Ratio of median survival time of treated mice (T) to that of median survival time of controls (C) in mice infected with p388 cells (in vivo) at a dose of 12.5 mg/kg | ChEMBL. | 15056007 |
T/C (functional) | = 300 % | Ratio of median survival time of treated mice (T) to that of median survival time of controls (C) in mice infected with p388 cells (in vivo) at a dose of 25 mg/kg | ChEMBL. | 15056007 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.