Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1247 | 0.4801 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0244 | 0.0496 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0023 | 0.0814 | 0.5567 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0132 | 0.0269 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0461 | 0.1772 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0244 | 0.0496 |
Brugia malayi | beta-lactamase | 0.0036 | 0.1382 | 0.2814 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.1731 | 0.6668 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0461 | 0.0925 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0591 | 0.833 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.1731 | 0.3481 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0244 | 0.0496 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0132 | 0.051 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1924 | 0.3869 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.1382 | 1 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0026 | 0.0053 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0244 | 0.0496 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.0864 | 0.5956 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.1382 | 0.1333 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0244 | 0.0937 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.2597 | 1 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0209 | 0.0419 |
Loa Loa (eye worm) | oxidoreductase | 0.0007 | 0.01 | 0.0201 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0547 | 0.0493 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0132 | 0.0269 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0132 | 0.0509 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0864 | 0.1758 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.1247 | 0.2538 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0244 | 0.0937 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.2597 | 0.5221 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.2597 | 0.5221 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0244 | 0.0489 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0209 | 0.0802 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0023 | 0.0814 | 0.5567 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0244 | 0.0496 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.1382 | 0.1333 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0244 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0591 | 0.1187 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1924 | 0.3869 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0007 | 0.01 | 0.0726 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0244 | 0.0939 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0007 | 0.01 | 0.0044 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0026 | 0.0102 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.1382 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.1382 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0461 | 0.1772 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0461 | 0.1773 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0209 | 0.0804 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0244 | 0.0496 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0244 | 0.0496 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.2597 | 1 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.01 | 0.0044 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0244 | 0.0489 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.1382 | 0.5322 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0007 | 0.01 | 0.0204 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.01 | 0.0201 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0244 | 0.0496 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.1382 | 0.2814 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0026 | 0.0052 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.1731 | 0.6668 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0591 | 0.0537 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0244 | 0.0496 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.1382 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0864 | 0.5956 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.1382 | 0.1333 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2597 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.491 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0864 | 0.1736 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.1731 | 0.6668 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0864 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0209 | 0.0802 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.1382 | 0.1333 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0583 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.2597 | 0.5288 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0007 | 0.01 | 0.0044 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2597 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2597 | 1 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.01 | 0.0044 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0209 | 0.0424 |
Brugia malayi | RNA binding protein | 0.0064 | 0.2597 | 0.5288 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0583 | 0.3761 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1382 | 0.2779 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.1382 | 1 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0007 | 0.01 | 0.0385 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0864 | 0.5956 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0864 | 0.1758 |
Onchocerca volvulus | 0.0007 | 0.01 | 0.0724 | |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0132 | 0.051 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.0864 | 0.5956 |
Loa Loa (eye worm) | RecQ helicase | 0.0023 | 0.0814 | 0.1636 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0864 | 0.1736 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0461 | 0.1773 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.0864 | 0.5956 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0132 | 0.0266 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0244 | 0.0937 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1924 | 0.3918 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0132 | 0.0266 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0461 | 0.1772 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0132 | 0.051 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2597 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0864 | 0.1736 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.1382 | 1 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0007 | 0.01 | 0.0044 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0244 | 0.0939 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0244 | 0.0496 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0583 | 0.2243 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0591 | 0.1187 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0007 | 0.01 | 0.0044 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0334 | 0.1821 |
Echinococcus granulosus | bloom syndrome protein | 0.0023 | 0.0814 | 0.3134 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0583 | 0.3761 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0244 | 0.0937 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0583 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.2597 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0334 | 0.1821 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0007 | 0.01 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1382 | 0.2779 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0244 | 0.0939 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.01 | 0.0044 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.01 | 0.0204 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.1382 | 0.5323 |
Toxoplasma gondii | propionate-CoA ligase | 0.0007 | 0.01 | 0.0726 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0461 | 0.1773 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0244 | 0.0489 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0461 | 0.0937 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0583 | 0.8193 |
Onchocerca volvulus | 0.0007 | 0.01 | 0.0724 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0026 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0026 | 0.0052 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.1382 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0591 | 0.3824 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0244 | 0.0489 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.01 | 0.0204 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0244 | 0.0937 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0461 | 0.1772 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0583 | 0.3761 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0026 | 0.0052 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.1382 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0026 | 0.0053 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0583 | 0.6744 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0864 | 0.5956 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0132 | 0.051 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.1382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1247 | 0.2506 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0026 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0244 | 0.0489 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0007 | 0.01 | 0.0387 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.1382 | 0.2814 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0244 | 0.0489 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0026 | 0.01 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0244 | 0.0937 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0244 | 0.0937 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.491 | 0.9875 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0244 | 0.0496 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.1382 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0583 | 0.2242 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.1382 | 0.1333 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.0864 | 0.5956 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0007 | 0.01 | 0.0044 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.0864 | 0.5956 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0209 | 0.0802 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0244 | 0.0939 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0334 | 0.1821 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0244 | 0.0489 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0244 | 0.0496 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0007 | 0.01 | 0.0385 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0244 | 0.0939 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0244 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0591 | 0.1187 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0591 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0132 | 0.0266 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0244 | 0.0937 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.1731 | 0.6668 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0132 | 0.0509 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0132 | 0.0269 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0583 | 0.4214 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0472 | 0.3414 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.1382 | 0.1333 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0023 | 0.0814 | 0.1657 |
Echinococcus granulosus | smad | 0.0008 | 0.0132 | 0.0509 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.01 | 0.0044 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0209 | 0.0802 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.1382 | 0.1333 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0244 | 0.0937 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0244 | 0.0496 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.1382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0026 | 0.0052 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0461 | 0.0937 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0244 | 0.1761 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.491 | 0.9875 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.2597 | 0.5221 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0244 | 0.0939 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0864 | 0.1758 |
Brugia malayi | Smad1 | 0.0008 | 0.0132 | 0.0269 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0132 | 0.051 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0583 | 0.3761 |
Echinococcus multilocularis | bloom syndrome protein | 0.0023 | 0.0814 | 0.3134 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0244 | 0.0489 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0132 | 0.0269 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0244 | 0.0939 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0244 | 0.0489 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0334 | 0.1821 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.1382 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0583 | 0.1171 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0547 | 0.0493 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.0864 | 0.5956 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0461 | 0.1772 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0244 | 0.0939 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0244 | 0.0496 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0461 | 0.1773 |
Onchocerca volvulus | 0.001 | 0.0244 | 0.1761 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.1731 | 0.3526 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1382 | 0.2779 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.1382 | 0.1333 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1924 | 0.3918 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0244 | 0.0489 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.1382 | 0.5323 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0244 | 0.0489 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.048 | 0.2963 |
Onchocerca volvulus | 0.0036 | 0.1382 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1382 | 0.2779 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0244 | 0.0496 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0547 | 0.0493 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.001 | 0.0209 | 0.184 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0583 | 0.3761 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0583 | 0.2242 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0132 | 0.0509 |
Onchocerca volvulus | 0.0036 | 0.1382 | 1 | |
Onchocerca volvulus | 0.0007 | 0.01 | 0.0724 | |
Onchocerca volvulus | 0.0036 | 0.1382 | 1 | |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0132 | 0.0509 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0026 | 0.01 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.1382 | 0.1333 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0461 | 0.1772 |
Schistosoma mansoni | smad | 0.0008 | 0.0132 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0244 | 0.0489 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0026 | 0.0053 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0597 | 0.23 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0244 | 0.0496 |
Onchocerca volvulus | 0.0025 | 0.0864 | 0.6248 | |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0244 | 0.0496 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0864 | 0.0812 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0244 | 0.0939 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0583 | 0.3761 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0583 | 0.3761 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.1382 | 0.5322 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0244 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.4973 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0583 | 0.0529 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.1382 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0244 | 0.0937 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.1382 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0547 | 0.0493 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.1382 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1382 | 0.2779 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0244 | 0.1761 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0244 | 0.0939 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0244 | 0.0937 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0007 | 0.01 | 0.0204 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0864 | 0.5956 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.01 | 0.0204 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.1382 | 0.1333 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.1382 | 0.2779 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.01 | 0.0201 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0864 | 1 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0689 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.01 | 0.0204 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0026 | 0.0052 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0209 | 0.0804 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0209 | 0.151 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0461 | 0.0925 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0591 | 0.1187 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0007 | 0.01 | 0.0044 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0244 | 0.0937 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0244 | 0.0939 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0244 | 0.0489 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0209 | 0.0419 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0209 | 0.151 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0583 | 0.1186 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.01 | 0.0201 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.1731 | 0.6668 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0007 | 0.01 | 0.0726 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0334 | 0.3865 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0132 | 0.0509 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.1382 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0209 | 0.0424 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.1382 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0591 | 0.3824 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0244 | 0.0937 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0244 | 0.0937 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.2597 | 0.5288 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.01 | 0.0201 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0244 | 0.0939 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0244 | 0.0937 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0583 | 0.2243 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0591 | 0.1187 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.0864 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0244 | 0.0489 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0583 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.1382 | 0.2779 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1382 | 0.2779 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.1382 | 0.2814 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0244 | 0.0939 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.1731 | 0.6668 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.0864 | 0.0812 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0244 | 0.0489 |
Onchocerca volvulus | 0.0007 | 0.01 | 0.0724 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0864 | 0.5956 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.1382 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0244 | 0.0496 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.01 | 0.0044 |
Echinococcus multilocularis | smad | 0.0008 | 0.0132 | 0.0509 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.1731 | 0.6668 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0583 | 0.3761 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0026 | 0.0053 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0244 | 0.0496 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0244 | 0.1761 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.0864 | 0.5956 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.1382 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0864 | 0.5956 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0026 | 0.0052 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0244 | 0.0489 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0244 | 0.0496 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0132 | 0.0509 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.