Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.6443 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0814 | 0.1264 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0814 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0814 | 0.5 |
Onchocerca volvulus | 0.0038 | 0.0814 | 0.5 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0814 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0814 | 0.1769 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0814 | 0.1769 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4602 | 0.7142 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0814 | 0.1769 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0814 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0814 | 0.1264 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0814 | 1 |
Brugia malayi | RNA binding protein | 0.0123 | 0.4602 | 1 |
Echinococcus multilocularis | geminin | 0.0164 | 0.6443 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0814 | 0.0814 |
Loa Loa (eye worm) | TAR-binding protein | 0.0123 | 0.4602 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4602 | 0.7142 |
Onchocerca volvulus | 0.0038 | 0.0814 | 0.5 | |
Echinococcus granulosus | tar DNA binding protein | 0.0123 | 0.4602 | 0.7142 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0814 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0814 | 0.0814 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0814 | 0.1264 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0814 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0123 | 0.4602 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0814 | 0.0814 |
Onchocerca volvulus | 0.0038 | 0.0814 | 0.5 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0814 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0814 | 0.0814 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0814 | 1 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0814 | 0.0814 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0814 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0814 | 0.1769 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0814 | 0.1769 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0814 | 0.0814 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0814 | 0.1264 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0814 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4602 | 0.7142 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0814 | 0.1769 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0814 | 0.0814 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0814 | 1 |
Echinococcus granulosus | geminin | 0.0164 | 0.6443 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0123 | 0.4602 | 0.7142 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4602 | 0.7142 |
Brugia malayi | TAR-binding protein | 0.0123 | 0.4602 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0123 | 0.4602 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0814 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0814 | 0.1769 |
Loa Loa (eye worm) | RNA binding protein | 0.0123 | 0.4602 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0814 | 0.0814 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0814 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0814 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0814 | 0.1769 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0814 | 0.1769 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0814 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0814 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0814 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.6443 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0814 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.4602 | 0.7142 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0814 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0814 | 0.1769 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0814 | 0.1769 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0814 | 0.0814 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0814 | 0.1769 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.