Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0035 | 0.0184 | 0.0374 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0041 | 0.0234 | 0.0514 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0019 | 0.0064 | 0.0178 |
Brugia malayi | Animal haem peroxidase family protein | 0.0025 | 0.0111 | 0.0319 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0016 | 0.0036 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Onchocerca volvulus | 0.0025 | 0.0111 | 0.0148 | |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.005 | 0.0304 | 0.0996 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0041 | 0.0234 | 0.0749 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.002 | 0.0069 | 0.0049 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0025 | 0.0109 | 0.0104 |
Loa Loa (eye worm) | DR-78 | 0.0019 | 0.0064 | 0.0159 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0027 | 0.0123 | 0.0172 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0019 | 0.0064 | 0.0159 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0041 | 0.0234 | 0.0679 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Toxoplasma gondii | Myb family DNA-binding domain-containing protein | 0.002 | 0.0068 | 0.0175 |
Brugia malayi | steroid hormone receptor | 0.0041 | 0.0234 | 0.0749 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0019 | 0.0064 | 0.0131 |
Loa Loa (eye worm) | CYP4Cod1 | 0.002 | 0.0069 | 0.0175 |
Onchocerca volvulus | 0.0049 | 0.0298 | 0.0727 | |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0069 | 0.0448 | 0.1755 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.0833 | 0.2513 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0164 | 0.0482 |
Onchocerca volvulus | Dual oxidase homolog | 0.0025 | 0.0111 | 0.0148 |
Brugia malayi | Animal haem peroxidase family protein | 0.0025 | 0.0111 | 0.0319 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0319 | 0.1347 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0019 | 0.0064 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0184 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0082 | 0.0214 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0027 | 0.0123 | 0.0172 |
Schistosoma mansoni | peroxidasin | 0.0025 | 0.0111 | 0.0238 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0016 | 0.0036 | 0.005 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.002 | 0.0069 | 0.0175 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0184 | 0.0739 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0025 | 0.0111 | 0.0148 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0041 | 0.0234 | 0.0514 |
Chlamydia trachomatis | phosphoshikimate 1-carboxyl vinyltransferase | 0.0364 | 0.2756 | 0.2741 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0052 | 0.0319 | 0.1302 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0164 | 0.0525 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0052 | 0.0319 | 0.1302 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0054 | 0.0332 | 0.098 |
Brugia malayi | nuclear hormone receptor | 0.0041 | 0.0234 | 0.0749 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0035 | 0.0726 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0432 | 0.3293 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0298 | 0.0657 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Mycobacterium ulcerans | putative regulatory protein | 0.0148 | 0.107 | 0.1052 |
Brugia malayi | glutathione reductase | 0.004 | 0.0225 | 0.0717 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0178 | 0.0388 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0019 | 0.0064 | 0.0131 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0064 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0234 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0164 | 0.0465 |
Schistosoma mansoni | single-minded | 0.02 | 0.1477 | 0.331 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.0067 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0082 | 0.0172 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0164 | 0.0504 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0025 | 0.0109 | 0.0104 |
Brugia malayi | conserved hypotetical protein | 0.0019 | 0.0064 | 0.0153 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0184 | 0.0208 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.012 | 0.0436 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0041 | 0.0234 | 0.0749 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0184 | 0.0544 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0014 | 0.002 | 0.0045 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0184 | 0.0739 |
Brugia malayi | PAS domain containing protein | 0.02 | 0.1477 | 0.5108 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0101 | 0.0705 | 0.0985 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.0054 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0069 | 0.0448 | 0.15 |
Brugia malayi | Blistered cuticle protein 3 | 0.0025 | 0.0111 | 0.0319 |
Mycobacterium ulcerans | polyketide synthase | 0.0027 | 0.0123 | 0.0103 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0091 | 0.0625 | 0.0874 |
Brugia malayi | tailless protein | 0.0019 | 0.0064 | 0.0153 |
Onchocerca volvulus | 0.024 | 0.1789 | 0.5365 | |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.0071 |
Brugia malayi | Thioredoxin reductase | 0.004 | 0.0225 | 0.0717 |
Leishmania major | trypanothione reductase | 0.004 | 0.0225 | 0.0892 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0184 | 0.0527 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.2872 | 0.8755 |
Schistosoma mansoni | nuclear hormone receptor | 0.0019 | 0.0064 | 0.0131 |
Mycobacterium ulcerans | polyketide synthase | 0.0025 | 0.0109 | 0.0089 |
Mycobacterium leprae | PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA | 0.0926 | 0.7156 | 1 |
Echinococcus multilocularis | geminin | 0.017 | 0.1242 | 0.3762 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0319 | 0.1347 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0019 | 0.0064 | 0.0153 |
Brugia malayi | Pax transcription factor protein 2 | 0.024 | 0.1789 | 0.6201 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.0833 | 0.285 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0301 | 0.0884 |
Toxoplasma gondii | shikimate dehydrogenase substrate binding domain-containing protein | 0.0364 | 0.2756 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0019 | 0.0064 | 0.0178 |
Schistosoma mansoni | nuclear receptor | 0.0019 | 0.0064 | 0.0131 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0163 | 0.0479 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0378 | 0.2872 | 1 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0018 | 0.0053 | 0.012 |
Mycobacterium leprae | probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS | 0.0364 | 0.2756 | 0.382 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0184 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0025 | 0.0109 | 0.0312 |
Giardia lamblia | Myb 1-like protein | 0.002 | 0.0068 | 0.0217 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0041 | 0.0234 | 0.0679 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0019 | 0.0064 | 0.0178 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0052 | 0.0319 | 0.1302 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Plasmodium vivax | glutathione reductase, putative | 0.004 | 0.0225 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.0833 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0082 | 0.0217 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0023 | 0.0093 | 0.013 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0041 | 0.0234 | 0.0514 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0041 | 0.0234 | 0.0695 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0035 | 0.0065 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0035 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0091 | 0.0625 | 0.0828 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0052 | 0.0319 | 0.1302 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.025 | 0.1 |
Trypanosoma brucei | cytochrome P450, putative | 0.002 | 0.0069 | 0.0214 |
Trypanosoma cruzi | cytochrome P450, putative | 0.002 | 0.0069 | 0.0214 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.002 | 0.0067 | 0.0047 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0022 | 0.0082 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0184 | 0.0527 |
Brugia malayi | Animal haem peroxidase family protein | 0.0025 | 0.0111 | 0.0319 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0184 | 0.0527 |
Trichomonas vaginalis | pc-MYB2, putative | 0.002 | 0.0068 | 0.0214 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0184 | 0.0257 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0035 | 0.007 |
Brugia malayi | Animal haem peroxidase family protein | 0.0025 | 0.0111 | 0.0319 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0184 | 0.0257 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0041 | 0.0234 | 0.0529 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0052 | 0.0319 | 0.1347 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0023 | 0.0093 | 0.0081 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.0052 |
Brugia malayi | bHLH-PAS transcription factor | 0.0148 | 0.107 | 0.3682 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Echinococcus granulosus | geminin | 0.017 | 0.1242 | 0.3762 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.0109 | 0.0089 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0052 | 0.0319 | 0.1347 |
Trichomonas vaginalis | pc-MYB2, putative | 0.002 | 0.0068 | 0.0214 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0025 | 0.0109 | 0.0153 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0027 | 0.0123 | 0.0103 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0035 | 0.0065 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.009 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0184 | 0.0257 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.1242 | 0.2782 |
Onchocerca volvulus | 0.0035 | 0.0184 | 0.0374 | |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0297 | 0.2235 | 0.2219 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0041 | 0.0234 | 0.0695 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0019 | 0.0064 | 0.0178 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0184 | 0.0257 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0082 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0082 | 0.0214 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0052 | 0.0319 | 0.1347 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0027 | 0.0123 | 0.0172 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0026 | 0.0115 | 0.0316 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0184 | 0.0257 |
Leishmania major | cytochrome p450-like protein | 0.002 | 0.0069 | 0.0214 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.002 | 0.0068 | 0.0214 |
Mycobacterium leprae | Possible regulatory protein | 0.0052 | 0.0319 | 0.0397 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0025 | 0.0111 | 0.0304 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0164 | 0.0482 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0184 | 0.0257 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.025 | 0.1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.012 | 0.4894 |
Onchocerca volvulus | 0.0302 | 0.2276 | 0.6881 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0019 | 0.0064 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0184 | 0.0164 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0221 | 0.1638 | 0.4976 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0145 | 0.1047 | 0.142 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0082 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0035 | 0.009 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.002 | 0.0068 | 0.0095 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0184 | 0.0739 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.009 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.002 | 0.0069 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0035 | 0.007 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0035 | 0.0066 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.002 | 0.0067 | 0.0047 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.004 | 0.0222 | 0.066 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.0054 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0019 | 0.0064 | 0.0159 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.002 | 0.0068 | 0.0214 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0164 | 0.0357 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0041 | 0.0234 | 0.0749 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0041 | 0.0234 | 0.0695 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0041 | 0.0234 | 0.0695 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0184 | 0.0208 |
Leishmania major | protein kinase, putative | 0.0052 | 0.0319 | 0.1302 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.012 | 0.0436 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0149 | 0.0324 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0149 | 0.042 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.004 | 0.0225 | 0.0314 |
Onchocerca volvulus | Peroxidase homolog | 0.0025 | 0.0111 | 0.0148 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0041 | 0.0234 | 0.0679 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.002 | 0.0068 | 0.0214 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0297 | 0.2235 | 1 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0148 | 0.107 | 0.324 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0091 | 0.0625 | 0.0874 |
Brugia malayi | nuclear hormone receptor | 0.0019 | 0.0064 | 0.0153 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0041 | 0.0234 | 0.0529 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0019 | 0.0064 | 0.0131 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0184 | 0.0714 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0035 | 0.0066 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0041 | 0.0234 | 0.0749 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.1242 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0035 | 0.009 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0041 | 0.0234 | 0.0679 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.009 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0184 | 0.0574 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0164 | 0.0482 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0184 | 0.0714 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0027 | 0.0123 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Schistosoma mansoni | nuclear receptor | 0.0019 | 0.0064 | 0.0131 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0184 | 0.0402 |
Brugia malayi | nuclear receptor RXR | 0.0019 | 0.0064 | 0.0153 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0041 | 0.0234 | 0.0695 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0145 | 0.1048 | 0.4484 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.002 | 0.0068 | 0.0217 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0184 | 0.0714 |
Onchocerca volvulus | 0.0041 | 0.0234 | 0.0529 | |
Mycobacterium ulcerans | thioesterase | 0.0023 | 0.0093 | 0.0073 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0052 | 0.0319 | 0.1347 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0184 | 0.0527 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0301 | 0.0983 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0301 | 0.0983 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0025 | 0.0111 | 0.0304 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0234 | 0.0679 |
Brugia malayi | nuclear receptor RXR | 0.0022 | 0.0082 | 0.0217 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0025 | 0.0111 | 0.0304 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0041 | 0.0234 | 0.0695 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0052 | 0.0319 | 0.1347 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0145 | 0.1047 | 0.1463 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0014 | 0.002 | 0.0034 |
Echinococcus multilocularis | peroxidasin | 0.0025 | 0.0111 | 0.0322 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0041 | 0.0234 | 0.0749 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.0109 | 0.0153 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0035 | 0.009 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0115 | 0.0333 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0041 | 0.0234 | 0.0695 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0149 | 0.0452 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.058 | 0.4451 | 1 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA | 0.0926 | 0.7156 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0025 | 0.0111 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0184 | 0.0527 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.0299 | 0.1019 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0041 | 0.0234 | 0.0695 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0184 | 0.0164 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0101 | 0.0705 | 0.0985 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0035 | 0.0726 |
Trypanosoma brucei | trypanothione reductase | 0.004 | 0.0225 | 0.0892 |
Onchocerca volvulus | Peroxidase homolog | 0.0025 | 0.0111 | 0.0148 |
Schistosoma mansoni | nuclear hormone receptor | 0.0041 | 0.0234 | 0.0514 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0027 | 0.0123 | 0.0123 |
Trichomonas vaginalis | MYB72, putative | 0.002 | 0.0068 | 0.0214 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.012 | 0.4894 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0.0035 | 0.0049 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.002 | 0.0068 | 0.0214 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.005 | 0.0304 | 0.0748 |
Trichomonas vaginalis | MYB3r3, putative | 0.002 | 0.0068 | 0.0214 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.009 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0164 | 0.0357 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.012 | 0.4894 |
Loa Loa (eye worm) | fatty acid synthase | 0.0027 | 0.0127 | 0.0351 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0027 | 0.0123 | 0.0123 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0041 | 0.0234 | 0.0679 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0041 | 0.0234 | 0.0529 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0041 | 0.0234 | 0.0749 |
Wolbachia endosymbiont of Brugia malayi | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1289 | 1 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0221 | 0.1638 | 0.5671 |
Plasmodium falciparum | thioredoxin reductase | 0.004 | 0.0225 | 1 |
Trichomonas vaginalis | C-MYB, putative | 0.002 | 0.0068 | 0.0214 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0025 | 0.0109 | 0.0153 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0052 | 0.0319 | 0.1302 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0082 | 0.0217 |
Loa Loa (eye worm) | pax transcription factor protein 2 | 0.024 | 0.1789 | 0.5438 |
Schistosoma mansoni | coup transcription factor | 0.0041 | 0.0234 | 0.0514 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0091 | 0.0625 | 0.0874 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0091 | 0.0625 | 0.0874 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.012 | 0.0331 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.0448 | 0.1347 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0184 | 0.0257 |
Onchocerca volvulus | 0.0025 | 0.0111 | 0.0148 | |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0184 | 0.0714 |
Echinococcus multilocularis | tumor protein p63 | 0.0337 | 0.2547 | 0.7732 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0184 | 0.0164 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0019 | 0.0064 | 0.0153 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0052 | 0.0319 | 0.1302 |
Brugia malayi | Cytochrome P450 family protein | 0.0031 | 0.0153 | 0.0466 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.0109 | 0.0089 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0035 | 0.0066 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.0448 | 0.1866 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0178 | 0.0507 |
Echinococcus granulosus | FTZ F1 alpha | 0.0041 | 0.0234 | 0.0695 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0178 | 0.0552 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0164 | 0.7027 |
Trichomonas vaginalis | MYB, putative | 0.002 | 0.0068 | 0.0217 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0041 | 0.0229 | 0.068 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.012 | 0.0436 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0019 | 0.0064 | 0.0178 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0019 | 0.0064 | 0.0178 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.0448 | 0.1866 |
Plasmodium vivax | thioredoxin reductase, putative | 0.004 | 0.0225 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0041 | 0.0234 | 0.0514 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0184 | 0.0164 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0041 | 0.0234 | 0.0695 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0052 | 0.0319 | 0.0299 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0041 | 0.0234 | 0.0514 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0041 | 0.0234 | 0.0695 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0035 | 0.0051 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0163 | 0.0479 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0145 | 0.1047 | 0.1029 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.012 | 0.0436 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0027 | 0.0123 | 0.0103 |
Onchocerca volvulus | 0.0251 | 0.1875 | 0.5634 | |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.0052 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0014 | 0.0022 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0319 | 0.0939 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0019 | 0.0064 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0035 | 0.009 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0027 | 0.0123 | 0.0172 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0163 | 0.0354 |
Toxoplasma gondii | thioredoxin reductase | 0.004 | 0.0225 | 0.0747 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0035 | 0.0066 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0041 | 0.0234 | 0.0749 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0234 | 0.0679 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0026 | 0.0115 | 0.0161 |
Brugia malayi | Cytochrome P450 family protein | 0.002 | 0.0069 | 0.0172 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0039 | 0.0217 | 0.0197 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.0109 | 0.0089 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0047 | 0.0092 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0025 | 0.0111 | 0.0304 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.3279 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0069 | 0.0448 | 0.1866 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0022 | 0.0082 | 0.0233 |
Treponema pallidum | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1289 | 1 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0035 | 0.0065 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0069 | 0.0448 | 0.1347 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0184 | 0.8014 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0064 | 0.0131 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0082 | 0.0217 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0164 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0184 | 0.0527 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0307 | 0.2312 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0251 | 0.1875 | 0.8376 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0184 | 0.0527 |
Brugia malayi | hypothetical protein | 0.0027 | 0.012 | 0.0351 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.0109 | 0.0089 |
Brugia malayi | Cytochrome P450 family protein | 0.002 | 0.0069 | 0.0172 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0022 | 0.0082 | 0.0233 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0082 | 0.0214 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0019 | 0.0064 | 0.0178 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.0448 | 0.0996 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0184 | 0.0257 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0234 | 0.0679 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0016 | 0.0036 | 0.0015 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0035 | 0.009 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.2276 | 0.6931 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0035 | 0.009 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0432 | 0.3293 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0184 | 0.0574 |
Onchocerca volvulus | 0.043 | 0.3279 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0041 | 0.0234 | 0.0749 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0041 | 0.0234 | 0.0695 |
Brugia malayi | Peroxidasin | 0.0025 | 0.0111 | 0.0319 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0184 | 0.0739 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0307 | 0.2312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0014 | 0.0005 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0041 | 0.0234 | 0.0749 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0052 | 0.0319 | 0.1347 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0091 | 0.0625 | 0.0874 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.2886 | 0.8796 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.002 | 0.0067 | 0.0044 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0041 | 0.0234 | 0.0749 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.015 | 0.0439 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0041 | 0.0234 | 0.0695 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0019 | 0.0064 | 0.0159 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0371 | 0.1281 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0069 | 0.0448 | 0.1866 |
Mycobacterium ulcerans | thioesterase TesA | 0.0023 | 0.0093 | 0.0073 |
Mycobacterium ulcerans | 3-phosphoshikimate 1-carboxyvinyltransferase | 0.0364 | 0.2756 | 0.2741 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0041 | 0.0234 | 0.0695 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0064 | 0.0153 |
Onchocerca volvulus | 0.0032 | 0.0164 | 0.0311 | |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0041 | 0.0234 | 0.0749 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0069 | 0.0448 | 0.1335 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0257 | 0.0751 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.025 | 0.1 |
Echinococcus granulosus | single minded 2 | 0.0148 | 0.107 | 0.324 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0184 | 0.0574 |
Brugia malayi | hypothetical protein | 0.0302 | 0.2276 | 0.7911 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0234 | 0.0679 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.004 | 0.0225 | 0.0892 |
Schistosoma mansoni | peroxidasin | 0.0025 | 0.0111 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Onchocerca volvulus | 0.003 | 0.0149 | 0.0266 | |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0234 | 0.0679 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0307 | 0.2312 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0041 | 0.0234 | 0.0514 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0025 | 0.0111 | 0.0304 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0039 | 0.0217 | 0.0303 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0041 | 0.0234 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0052 | 0.0319 | 0.1347 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.1048 | 0.4484 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0019 | 0.0064 | 0.0153 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0041 | 0.0234 | 0.0695 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0019 | 0.0064 | 0.0153 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0041 | 0.0234 | 0.0695 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0164 | 0.0357 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0222 | 0.1651 | 0.2307 |
Plasmodium falciparum | glutathione reductase | 0.004 | 0.0225 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0035 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0298 | 0.0874 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0041 | 0.0234 | 0.0749 |
Mycobacterium tuberculosis | Probable reductase | 0.0091 | 0.0625 | 0.0874 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0019 | 0.0064 | 0.0153 |
Mycobacterium ulcerans | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1289 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.025 | 0.1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0041 | 0.0229 | 0.068 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0101 | 0.0705 | 0.094 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0035 | 0.0065 |
Trichomonas vaginalis | C-MYB, putative | 0.002 | 0.0068 | 0.0214 |
Brugia malayi | ecdysteroid receptor | 0.0041 | 0.0234 | 0.0749 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0234 | 0.0679 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0035 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Leishmania major | protein kinase, putative | 0.0052 | 0.0319 | 0.1302 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0027 | 0.0123 | 0.0123 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0014 | 0.002 | 0.0028 |
Loa Loa (eye worm) | glutathione reductase | 0.004 | 0.0225 | 0.0651 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0053 | 0.0323 | 0.1322 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0041 | 0.0234 | 0.0695 |
Loa Loa (eye worm) | thioredoxin reductase | 0.004 | 0.0225 | 0.0651 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0052 | 0.0319 | 0.1302 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0082 | 0.0214 |
Schistosoma mansoni | thyroid hormone receptor | 0.0041 | 0.0234 | 0.0514 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0319 | 0.1046 |
Onchocerca volvulus | Peroxidasin homolog | 0.0025 | 0.0111 | 0.0148 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0041 | 0.0234 | 0.0749 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0041 | 0.0234 | 0.0749 |
Mycobacterium ulcerans | hypothetical protein | 0.0162 | 0.1176 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Schistosoma mansoni | nuclear hormone receptor | 0.0019 | 0.0064 | 0.0131 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0066 | 0.0425 | 0.0943 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0052 | 0.0319 | 0.1347 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0031 | 0.0153 | 0.0432 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.012 | 0.0366 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0014 | 0.002 | 0.0045 |
Brugia malayi | nuclear receptor NHR-88 | 0.0041 | 0.0234 | 0.0749 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.002 | 0.0067 | 0.017 |
Onchocerca volvulus | 0.0035 | 0.0184 | 0.0374 | |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0019 | 0.0064 | 0.0178 |
Echinococcus granulosus | tumor protein p63 | 0.0337 | 0.2547 | 0.7732 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0041 | 0.0234 | 0.0679 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0101 | 0.0705 | 0.0985 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0184 | 0.0574 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0041 | 0.0234 | 0.0514 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0304 |
Onchocerca volvulus | 0.0048 | 0.0291 | 0.0706 | |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0054 | 0.0332 | 0.0994 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0041 | 0.0234 | 0.0514 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0184 | 0.0257 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0297 | 0.2235 | 1 |
Onchocerca volvulus | 0.015 | 0.1084 | 0.3172 | |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.002 | 0.0068 | 0.0217 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0041 | 0.0234 | 0.0695 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0162 | 0.1176 | 0.1644 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0019 | 0.0064 | 0.0178 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0022 | 0.0082 | 0.0172 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.002 | 0.0068 | 0.0214 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0039 | 0.0217 | 0.0303 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0301 | 0.0884 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0184 | 0.0739 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0184 | 0.0164 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0307 | 0.2312 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0041 | 0.0234 | 0.0679 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0184 | 0.0402 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0041 | 0.0234 | 0.0749 |
Brugia malayi | nuclear receptor NHR-67 | 0.0019 | 0.0064 | 0.0153 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0019 | 0.0064 | 0.0153 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.002 | 0.0068 | 0.0214 |
Schistosoma mansoni | thyroid hormone receptor | 0.0041 | 0.0234 | 0.0514 |
Onchocerca volvulus | 0.0026 | 0.0115 | 0.016 | |
Echinococcus granulosus | transcription factor Dp 1 | 0.004 | 0.0222 | 0.066 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0234 | 0.0679 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.002 | 0.007 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0064 | 0.0159 |
Brugia malayi | ecdysone receptor | 0.0019 | 0.0064 | 0.0153 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0039 | 0.0217 | 0.0255 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0019 | 0.0064 | 0.0178 |
Trypanosoma cruzi | cytochrome P450, putative | 0.002 | 0.0069 | 0.0214 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0054 | 0.0332 | 0.0994 |
Brugia malayi | Animal haem peroxidase family protein | 0.0025 | 0.0111 | 0.0319 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0184 | 0.0257 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0319 | 0.1347 |
Echinococcus granulosus | peroxidasin | 0.0025 | 0.0111 | 0.0322 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0163 | 0.0354 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0111 | 0.0319 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0184 | 0.0739 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0184 | 0.0527 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0027 | 0.0123 | 0.0172 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.1048 | 0.4484 |
Onchocerca volvulus | 0.0025 | 0.0111 | 0.0148 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0035 | 0.0051 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0041 | 0.0234 | 0.0514 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0041 | 0.0234 | 0.0749 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
K ass (binding) | = 12000000 l M-1 | Binding affinity for human Coagulation factor X | ChEMBL. | 10841787 |
K ass (binding) | = 12000000 l M-1 | Binding affinity for human Coagulation factor X | ChEMBL. | 10841787 |
PT (functional) | = 2.4 uM | Prothrombin time activity, concentration required to double the time of clot formation in the prothrombin time assay | ChEMBL. | 10841787 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.