Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.4478 | 0.5 |
Onchocerca volvulus | 0.0029 | 0.5782 | 0.5 | |
Echinococcus multilocularis | musashi | 0.0029 | 0.5782 | 0.5697 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.5584 | 0.9658 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.4478 | 0.5 |
Echinococcus multilocularis | lamin | 0.0029 | 0.5782 | 0.5697 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.4478 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.4478 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.4478 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.5782 | 0.543 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.5782 | 0.5697 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.5782 | 0.543 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.5782 | 1 |
Onchocerca volvulus | 0.0029 | 0.5782 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.5782 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.1115 | 0.0373 |
Echinococcus granulosus | lamin | 0.0029 | 0.5782 | 0.5697 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.5782 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.4478 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.4478 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.5782 | 0.5697 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0342 |
Brugia malayi | hypothetical protein | 0.0026 | 0.4478 | 0.4017 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.4478 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.5782 | 0.5697 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0771 | 0.1333 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.4478 | 0.7746 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.