Detailed information for compound 1075930

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 294.371 | Formula: C17H14N2OS
  • H donors: 2 H acceptors: 1 LogP: 3.07 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1ccc2c(c1)c1CC(=O)Nc3c(c1[nH]2)cccc3
  • InChi: 1S/C17H14N2OS/c1-21-10-6-7-15-12(8-10)13-9-16(20)18-14-5-3-2-4-11(14)17(13)19-15/h2-8,19H,9H2,1H3,(H,18,20)
  • InChiKey: RIZKGLUNPDBCNN-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cyclin B3 Starlite/ChEMBL References
Homo sapiens glycogen synthase kinase 3 beta Starlite/ChEMBL References
Homo sapiens cyclin B1 References
Homo sapiens cyclin-dependent kinase 3 References
Homo sapiens cyclin B2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium hominis mitotic cyclin-CYC2 Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania braziliensis CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia G2/mitotic-specific cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Onchocerca volvulus Get druggable targets OG5_126649 All targets in OG5_126649
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania donovani cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium berghei glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans likely G2 B-type cyclin similar to S. cerevisiae CLB1 (YPR119W) which is involved in mitotic induction Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus granulosus protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium parvum cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania mexicana CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania mexicana cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Plasmodium vivax glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Brugia malayi intracellular kinase Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans likely B-type cyclin similar to S. cerevisiae CLB4 (YLR210W) and CLB3 (YDL155W) involved in G1/S transition Get druggable targets OG5_126649 All targets in OG5_126649
Onchocerca volvulus Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_126649 All targets in OG5_126649
Plasmodium falciparum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma brucei gambiense cyclin 6,mitotic cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma japonicum IPR002155,Thiolase,domain-containing Get druggable targets OG5_134175 All targets in OG5_134175
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Theileria parva glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium knowlesi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense mitotic cyclin 6 Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus multilocularis cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania braziliensis protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania donovani glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum ko:K05868 cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania mexicana protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma japonicum ko:K08822 glycogen synthase kinase 3 alpha, putative Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans Serine/threonine protein kinase required for induction of IME2 by Ime1p Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium parvum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_134175 All targets in OG5_134175
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Candida albicans likely G2 B-type cyclin similar to S. cerevisiae CLB1 (YPR119W) which is involved in mitotic induction Get druggable targets OG5_126649 All targets in OG5_126649
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus G2:mitotic specific cyclin B3 Get druggable targets OG5_134175 All targets in OG5_134175
Trypanosoma cruzi cyclin 6, putative Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) cyclin domain-containing protein Get druggable targets OG5_134175 All targets in OG5_134175
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Entamoeba histolytica cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126649 All targets in OG5_126649
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania major cyclin Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclin A, putative Get druggable targets OG5_126649 All targets in OG5_126649
Brugia malayi Cyclin, N-terminal domain containing protein Get druggable targets OG5_126649 All targets in OG5_126649
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K05868 cyclin B, putative Get druggable targets OG5_134175 All targets in OG5_134175
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma cruzi CYC2-like cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni cyclin B3 Get druggable targets OG5_134175 All targets in OG5_134175
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani CYC2-like cyclin, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei mitotic cyclin 6 Get druggable targets OG5_126649 All targets in OG5_126649
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni cyclin B Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma congolense Cyclin, N-terminal domain/Cyclin, C-terminal domain containing protein, putative Get druggable targets OG5_126649 All targets in OG5_126649
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis G2:mitotic specific cyclin B3 Get druggable targets OG5_134175 All targets in OG5_134175
Trichomonas vaginalis cyclins, putative Get druggable targets OG5_126649 All targets in OG5_126649
Trichomonas vaginalis cyclin B, putative Get druggable targets OG5_126649 All targets in OG5_126649
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 3 305 aa 303 aa 32.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi MH1 domain containing protein 0.001 0.0231 0.0221
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0253 0.0023
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0124 0.6157 1
Plasmodium falciparum cyclin 0.0064 0.3059 1
Trypanosoma brucei cdc2-related kinase 1 0.0053 0.2458 0.3568
Onchocerca volvulus 0.0124 0.6157 1
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0538 0.0232
Echinococcus granulosus cyclin 0.0016 0.0538 0.0315
Echinococcus multilocularis cyclin dependent kinase 1 0.0053 0.2458 0.2279
Brugia malayi Cyclin, N-terminal domain containing protein 0.0124 0.6157 0.6153
Echinococcus granulosus cyclin dependent kinase 0.0053 0.2458 0.2279
Trypanosoma cruzi mitotic cyclin, putative 0.0016 0.0538 0.0232
Schistosoma mansoni smad 0.001 0.0231 0.0231
Trypanosoma brucei cyclin 3 0.0016 0.0538 0.0232
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0538 0.0529
Entamoeba histolytica acetyltransferase, GNAT family 0.0046 0.2108 0.3423
Toxoplasma gondii cyclin 4, putative 0.0016 0.0538 0.1719
Schistosoma mansoni cyclin l 0.0016 0.0538 0.0538
Trypanosoma cruzi cyclin, putative 0.0124 0.6157 1
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0253 0.0023
Echinococcus multilocularis cyclins 0.0064 0.3059 0.2895
Echinococcus granulosus cyclin t1 0.0016 0.0538 0.0315
Trichomonas vaginalis cyclins, putative 0.0124 0.6157 1
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.3059 0.4614
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.3132 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.2323 0.3335
Trypanosoma cruzi mitotic cyclin, putative 0.0016 0.0538 0.0232
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0685 0.0487
Echinococcus granulosus protein kinase shaggy 0.0059 0.2764 0.2593
Schistosoma mansoni Cyclin fold protein 0.0016 0.0538 0.0538
Entamoeba histolytica cyclin family protein 0.0064 0.3059 0.4968
Leishmania major cyclin 9, putative 0.0016 0.0538 0.0232
Schistosoma mansoni hypothetical protein 0.0171 0.8568 0.8568
Echinococcus granulosus cyclins 0.0064 0.3059 0.2895
Brugia malayi hypothetical protein 0.0019 0.0725 0.0716
Giardia lamblia Hypothetical protein 0.0064 0.3059 0.4752
Trypanosoma cruzi cdc2-related kinase 1 0.0053 0.2458 0.3568
Echinococcus granulosus cyclins 0.0064 0.3059 0.2895
Trichomonas vaginalis cyclin B3, putative 0.0016 0.0538 0.0232
Entamoeba histolytica hypothetical protein 0.0016 0.0538 0.0874
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0059 0.2764 0.2593
Giardia lamblia Kinase, CMGC CDK 0.0053 0.2458 0.3734
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0538 0.0232
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.2323 0.2142
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0059 0.2764 0.8825
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0538 0.0529
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0253 0.0809
Entamoeba histolytica cell division protein kinase 2, putative 0.0053 0.2458 0.3991
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0053 0.2458 0.245
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0538 0.0529
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0538 0.0232
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0685 0.1113
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.2294 0.2287
Brugia malayi Smad1 0.001 0.0231 0.0221
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0685 0.0487
Entamoeba histolytica cyclin, domain containing protein 0.0016 0.0538 0.0874
Schistosoma mansoni hypothetical protein 0.0016 0.0538 0.0538
Schistosoma mansoni DNA helicase recq5 0.001 0.0253 0.0253
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.017 0.8532 0.8532
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0059 0.2764 0.41
Giardia lamblia Histone acetyltransferase GCN5 0.0046 0.2108 0.3141
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.2294 0.2294
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.3132 1
Loa Loa (eye worm) transcription factor SMAD2 0.014 0.6987 0.6984
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0538 0.0232
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0016 0.0538 0.1719
Echinococcus granulosus cyclins 0.0016 0.0538 0.0315
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0016 0.0538 0.1017
Echinococcus granulosus cyclin B3 1 0.0064 0.3059 0.2895
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0059 0.2764 0.41
Trichomonas vaginalis cyclin D, putative 0.0064 0.3059 0.4614
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.3132 1
Schistosoma mansoni cyclin G 0.0016 0.0538 0.0538
Schistosoma mansoni hypothetical protein 0.0013 0.0423 0.0423
Echinococcus multilocularis cyclin k 0.0016 0.0538 0.0315
Brugia malayi hypothetical protein 0.003 0.1268 0.1259
Schistosoma mansoni cyclins 0.0064 0.3059 0.3059
Echinococcus granulosus cyclins 0.0064 0.3059 0.2895
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.2458 0.2458
Brugia malayi cyclin fold protein 1 variant b 0.0016 0.0538 0.0529
Trichomonas vaginalis cyclin A, putative 0.0016 0.0538 0.0232
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0988 0.1013
Trichomonas vaginalis cyclin B, putative 0.0124 0.6157 1
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.3132 0.3132
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.2294 0.2112
Trypanosoma cruzi cdc2-related kinase 3 0.0053 0.2458 0.3568
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0016 0.0538 0.1719
Echinococcus multilocularis cyclins 0.0064 0.3059 0.2895
Loa Loa (eye worm) Smad1 0.001 0.0231 0.0221
Schistosoma mansoni hypothetical protein 0.0016 0.0538 0.0538
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.1268 0.4047
Brugia malayi MH2 domain containing protein 0.014 0.6987 0.6984
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.3132 0.3132
Echinococcus granulosus Cyclin L1 0.0016 0.0538 0.0315
Loa Loa (eye worm) acetyltransferase 0.017 0.8532 0.8531
Trichomonas vaginalis cyclin B, putative 0.0124 0.6157 1
Echinococcus granulosus cyclin k 0.0016 0.0538 0.0315
Loa Loa (eye worm) hypothetical protein 0.0124 0.6157 0.6153
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0685 0.0465
Toxoplasma gondii exonuclease III APE 0.0018 0.0685 0.2188
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0988 0.0979
Trichomonas vaginalis cyclins, putative 0.0016 0.0538 0.0232
Trichomonas vaginalis cyclin B, putative 0.0016 0.0538 0.0232
Trichomonas vaginalis cyclins, putative 0.0016 0.0538 0.0232
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0059 0.2764 0.2593
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0016 0.0538 0.0315
Trichomonas vaginalis cyclin B, putative 0.0064 0.3059 0.4614
Loa Loa (eye worm) cyclin C 0.0016 0.0538 0.0529
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.2294 0.2294
Loa Loa (eye worm) hypothetical protein 0.001 0.0253 0.0243
Echinococcus granulosus cyclin dependent kinase 1 0.0053 0.2458 0.2279
Echinococcus multilocularis Cyclin L1 0.0016 0.0538 0.0315
Trichomonas vaginalis cyclin B, putative 0.0124 0.6157 1
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0538 0.0529
Plasmodium falciparum cyclin 1 0.0016 0.0538 0.1017
Trichomonas vaginalis cyclin A, putative 0.0124 0.6157 1
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.2458 0.2458
Schistosoma mansoni smad1 5 8 and 0.001 0.0231 0.0231
Entamoeba histolytica cell division protein kinase 2, putative 0.0053 0.2458 0.3991
Schistosoma mansoni cyclin d 0.0016 0.0538 0.0538
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.3132 1
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0053 0.2458 0.2279
Giardia lamblia Cyclin fold protein 1, putative 0.0016 0.0538 0.0483
Schistosoma mansoni smad1 5 8 and 0.001 0.0231 0.0231
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0253 0.0023
Schistosoma mansoni cyclin k 0.0016 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.0122 0.6034 0.603
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0685 0.0732
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.1268 0.3276
Loa Loa (eye worm) CYL-1 protein 0.0016 0.0538 0.0529
Entamoeba histolytica cyclin family protein 0.0064 0.3059 0.4968
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0016 0.0538 0.0315
Plasmodium vivax protein kinase Crk2 0.0053 0.2458 0.8624
Loa Loa (eye worm) hypothetical protein 0.0052 0.24 0.2392
Leishmania major mitotic cyclin, putative 0.0016 0.0538 0.0232
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.2294 0.2112
Echinococcus multilocularis cyclin dependent kinase 1 0.0053 0.2458 0.2279
Schistosoma mansoni smad1 5 8 and 0.001 0.0231 0.0231
Echinococcus multilocularis cyclin y 0.0016 0.0538 0.0315
Brugia malayi MH1 domain containing protein 0.001 0.0231 0.0221
Echinococcus multilocularis cyclin G2 0.0016 0.0538 0.0315
Entamoeba histolytica protein kinase, putative 0.0059 0.2764 0.4489
Entamoeba histolytica cyclin, domain containing protein 0.0016 0.0538 0.0874
Plasmodium falciparum glycogen synthase kinase 3 0.0059 0.2764 0.8948
Schistosoma mansoni Smad4 0.001 0.0231 0.0231
Echinococcus multilocularis cyclins 0.0064 0.3059 0.2895
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0685 0.0676
Echinococcus granulosus histone acetyltransferase KAT2B 0.0165 0.8285 0.8245
Echinococcus multilocularis cyclins 0.0064 0.3059 0.2895
Echinococcus multilocularis cyclins 0.0064 0.3059 0.2895
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0016 0.0538 0.0529
Plasmodium falciparum histone acetyltransferase GCN5 0.0046 0.2108 0.661
Onchocerca volvulus 0.0059 0.2764 0.3961
Trypanosoma brucei cyclin 9 0.0016 0.0538 0.0232
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.3132 0.474
Plasmodium falciparum protein kinase 5 0.0053 0.2458 0.7857
Brugia malayi hypothetical protein 0.0016 0.0538 0.0529
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0538 0.0529
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0538 0.0529
Echinococcus granulosus cyclins 0.0064 0.3059 0.2895
Trichomonas vaginalis cyclins, putative 0.0124 0.6157 1
Brugia malayi hypothetical protein 0.0016 0.0538 0.0529
Loa Loa (eye worm) hypothetical protein 0.003 0.1268 0.1259
Schistosoma mansoni cyclin G2 0.0016 0.0538 0.0538
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.2764 0.4489
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0988 0.1013
Echinococcus granulosus cyclin G2 0.0016 0.0538 0.0315
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0059 0.2764 0.2756
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0685 0.0487
Leishmania major cyclin 0.0124 0.6157 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.2323 0.7419
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.2294 0.2112
Echinococcus multilocularis cyclin G2 0.0016 0.0538 0.0315
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.2294 0.2287
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.3132 0.2969
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0538 0.0232
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.1268 0.1499
Schistosoma mansoni g1/s-specific cyclin C 0.0016 0.0538 0.0538
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.017 0.8532 0.8497
Trypanosoma cruzi cyclin 6, putative 0.0124 0.6157 1
Giardia lamblia Cyclin B-like protein 0.0016 0.0538 0.0483
Trichomonas vaginalis cyclin B3, putative 0.0064 0.3059 0.4614
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0573 0.1829
Echinococcus granulosus cyclin y 0.0016 0.0538 0.0315
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.2294 0.2112
Echinococcus multilocularis protein kinase shaggy 0.0059 0.2764 0.2593
Giardia lamblia Kinase, CMGC GSK 0.0059 0.2764 0.4252
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0423 0.0197
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.2764 0.41
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0016 0.0538 0.1017
Brugia malayi Cyclin, N-terminal domain containing protein 0.0124 0.6157 0.6153
Trichomonas vaginalis cyclins, putative 0.0075 0.3637 0.5618
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.2323 0.8021
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0016 0.0538 0.0538
Entamoeba histolytica cyclin, putative 0.0064 0.3059 0.4968
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0253 0.0023
Echinococcus granulosus bloom syndrome protein 0.0024 0.0988 0.0775
Loa Loa (eye worm) hypothetical protein 0.0016 0.0538 0.0529
Leishmania major hypothetical protein, conserved 0.003 0.1268 0.1499
Echinococcus granulosus cyclin G2 0.0016 0.0538 0.0315
Toxoplasma gondii hypothetical protein 0.0049 0.2257 0.7207
Echinococcus multilocularis cyclin b3 0.0064 0.3059 0.2895
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0685 0.0487
Toxoplasma gondii hypothetical protein 0.0016 0.0538 0.1719
Loa Loa (eye worm) hypothetical protein 0.0016 0.0538 0.0529
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.3132 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.0231 0.0231
Trypanosoma brucei mitotic cyclin 6 0.0124 0.6157 1
Brugia malayi cell division control protein 2 homolog 0.0053 0.2458 0.245
Schistosoma mansoni hypothetical protein 0.0171 0.8568 0.8568
Echinococcus granulosus cyclin y 0.0016 0.0538 0.0315
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.0231 0.0221
Trypanosoma brucei protein kinase, putative 0.0059 0.2764 0.41
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0016 0.0538 0.0232
Trichomonas vaginalis cyclin D, putative 0.0016 0.0538 0.0232
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0059 0.2764 0.2756
Echinococcus granulosus cyclins 0.0064 0.3059 0.2895
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.3132 0.2969
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.2764 0.4489
Toxoplasma gondii cyclin dependent kinase binding protein 0.0016 0.0538 0.1719
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0988 0.0775
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0685 0.0676
Echinococcus multilocularis cyclin B3 1 0.0064 0.3059 0.2895
Trypanosoma cruzi cdc2-related kinase 1 0.0053 0.2458 0.3568
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0836 0.2077
Echinococcus granulosus geminin 0.0171 0.8568 0.8534
Brugia malayi intracellular kinase 0.0059 0.2764 0.2756
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0685 0.154
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.1268 0.1499
Giardia lamblia Hypothetical protein 0.0016 0.0538 0.0483
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0685 0.0465
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0685 0.5
Echinococcus granulosus cyclin B 0.0124 0.6157 0.6066
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0253 0.0809
Echinococcus multilocularis cyclin dependent kinase 5 0.0053 0.2458 0.2279
Trypanosoma cruzi cdc2-related kinase 3 0.0053 0.2458 0.3568
Brugia malayi Protein kinase domain containing protein 0.0053 0.2458 0.245
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0538 0.0529
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0059 0.2764 0.2764
Plasmodium vivax glycogen synthase kinase 3, putative 0.0059 0.2764 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0538 0.0529
Echinococcus multilocularis cyclins 0.0064 0.3059 0.2895
Loa Loa (eye worm) hypothetical protein 0.006 0.2835 0.2828
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0538 0.0529
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0053 0.2458 0.7847
Giardia lamblia G2/mitotic-specific cyclin B 0.0124 0.6157 1
Trichomonas vaginalis cyclins, putative 0.0124 0.6157 1
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0016 0.0538 0.0315
Echinococcus granulosus G1:S specific cyclin D1 0.0016 0.0538 0.0315
Echinococcus multilocularis cyclin dependent kinase 0.0053 0.2458 0.2279
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0538 0.0529
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.2294 0.2294
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.1268 0.3615
Brugia malayi Cyclin C 0.0016 0.0538 0.0529
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.2764 0.41
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.2458 0.3568
Giardia lamblia Kinase, CMGC GSK 0.0059 0.2764 0.4252
Schistosoma mansoni DNA helicase recq1 0.001 0.0253 0.0253
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.2323 0.7419
Schistosoma mansoni ap endonuclease 0.0018 0.0685 0.0685
Echinococcus multilocularis G1:S specific cyclin D1 0.0016 0.0538 0.0315
Echinococcus granulosus cyclin b3 0.0064 0.3059 0.2895
Brugia malayi acetyltransferase, GNAT family protein 0.017 0.8532 0.8531
Echinococcus granulosus cyclin A3 4 0.0016 0.0538 0.0315
Trichomonas vaginalis cyclins, putative 0.0064 0.3059 0.4614
Trichomonas vaginalis cyclins, putative 0.0124 0.6157 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0253 0.0243
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0253 0.0243
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0685 0.0659
Trichomonas vaginalis cyclin D, putative 0.0064 0.3059 0.4614
Trypanosoma cruzi cyclin 9, putative 0.0016 0.0538 0.0232
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.1268 0.3615
Loa Loa (eye worm) MH2 domain-containing protein 0.014 0.6987 0.6984
Schistosoma mansoni cyclin B 0.0124 0.6157 0.6157
Echinococcus multilocularis cyclin y 0.0016 0.0538 0.0315
Trypanosoma cruzi CYC2-like cyclin, putative 0.0124 0.6157 1
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.1268 0.1499
Loa Loa (eye worm) hypothetical protein 0.0124 0.6157 0.6153
Echinococcus multilocularis cyclin A3 4 0.0016 0.0538 0.0315
Brugia malayi MH2 domain containing protein 0.001 0.0231 0.0221
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0583 0.0199
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.2458 0.3568
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0016 0.0538 0.0315
Echinococcus multilocularis geminin 0.0171 0.8568 0.8534
Leishmania major mitotic cyclin, putative 0.0016 0.0538 0.0232
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.2323 0.3335
Echinococcus multilocularis cyclin 0.0016 0.0538 0.0315
Trichomonas vaginalis cyclin B3, putative 0.0016 0.0538 0.0232
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0685 0.5
Brugia malayi MH2 domain containing protein 0.001 0.0231 0.0221
Echinococcus granulosus cyclin dependent kinase 5 0.0053 0.2458 0.2279
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0053 0.2458 0.3568
Entamoeba histolytica cyclin C, putative 0.0016 0.0538 0.0874
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0538 0.0529
Loa Loa (eye worm) cyclin domain-containing protein 0.0016 0.0538 0.0529
Echinococcus multilocularis cyclin t1 0.0016 0.0538 0.0315
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0405 0.0658
Schistosoma mansoni ap endonuclease 0.0018 0.0685 0.0685
Trypanosoma cruzi cyclin, putative 0.0124 0.6157 1
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0053 0.2458 0.245
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.2458 0.3568
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0053 0.2458 0.3568
Entamoeba histolytica cyclin, putative 0.0124 0.6157 1
Giardia lamblia Cyclin A 0.0064 0.3059 0.4752
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0423 0.0197
Echinococcus multilocularis cyclins 0.0064 0.3059 0.2895
Trypanosoma brucei cdc2-related kinase 3 0.0053 0.2458 0.3568
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.0231 0.0221
Loa Loa (eye worm) RecQ helicase 0.0024 0.0988 0.0979
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0053 0.2458 0.245
Trichomonas vaginalis cyclin B, putative 0.0016 0.0538 0.0232
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0725 0.0725
Trichomonas vaginalis cyclin B, putative 0.0124 0.6157 1
Giardia lamblia Kinase, CMGC CDK 0.0053 0.2458 0.3734
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0685 0.0487
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0685 0.0487
Brugia malayi Cyclin, N-terminal domain containing protein 0.0016 0.0538 0.0529
Echinococcus multilocularis cyclin B 0.0124 0.6157 0.6066
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0253 0.0243
Giardia lamblia Hypothetical protein 0.0016 0.0538 0.0483
Trypanosoma brucei mitotic cyclin 0.0016 0.0538 0.0232

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 76.6 % Inhibition of mitochondrial malate dehydrogenase assessed as residual enzyme activity at 10 uM by spectrophotometry ChEMBL. 19906467
IC50 (binding) = 0.4 microM Inhibition of CDK1/cyclin B ChEMBL. 19906467
IC50 (binding) = 1.2 microM Inhibition of GSK3-beta ChEMBL. 19906467

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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